Brian Arthur Hemmings
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Brian Arthur Hemmingsbiology Degrees
Biology
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Biochemistry
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Chemistry Biology
Brian Arthur Hemmings's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry Stanford University
Why Is Brian Arthur Hemmings Influential?
(Suggest an Edit or Addition)Brian Arthur Hemmings's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B (1995) (5216)
- Mechanism of activation of protein kinase B by insulin and IGF‐1. (1996) (3060)
- The lipid phosphatase activity of PTEN is critical for its tumor supressor function. (1998) (1208)
- Ten years of protein kinase B signalling: a hard Akt to follow. (2001) (1185)
- Role of Translocation in the Activation and Function of Protein Kinase B* (1997) (1094)
- Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. (2000) (895)
- Protein Kinase SGK Mediates Survival Signals by Phosphorylating the Forkhead Transcription Factor FKHRL1 (FOXO3a) (2001) (889)
- Phosphorylation and activation of p70s6k by PDK1. (1998) (887)
- Advances in protein kinase B signalling: AKTion on multiple fronts. (2004) (871)
- Regulation of protein kinase cascades by protein phosphatase 2A. (1999) (831)
- Glycogen synthase kinase-3 from rabbit skeletal muscle. (1981) (811)
- PI3K-PKB/Akt pathway. (2012) (781)
- Structure, regulation and function of PKB/AKT--a major therapeutic target. (2004) (747)
- Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase‐1 and p70 S6 kinase (1996) (650)
- Serine/threonine protein phosphatases. (1995) (636)
- Serum and glucocorticoid‐inducible kinase (SGK) is a target of the PI 3‐kinase‐stimulated signaling pathway (1999) (575)
- PKB Binding Proteins Getting in on the Akt (2002) (557)
- Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. (1991) (548)
- Akt Signaling--Linking Membrane Events to Life and Death Decisions (1997) (527)
- Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. (1996) (513)
- Identification of a PKB/Akt Hydrophobic Motif Ser-473 Kinase as DNA-dependent Protein Kinase*♦ (2004) (507)
- Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNP (2002) (458)
- Pleckstrin domain homology (1993) (454)
- The Structure of the Protein Phosphatase 2A PR65/A Subunit Reveals the Conformation of Its 15 Tandemly Repeated HEAT Motifs (1999) (449)
- The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis (2000) (447)
- Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation. (2002) (426)
- High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity* (1997) (425)
- PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. (2008) (410)
- Mitogenic Activation, Phosphorylation, and Nuclear Translocation of Protein Kinase Bβ* (1997) (402)
- Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle. (1988) (363)
- Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. (1998) (343)
- Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction. (2008) (341)
- Protein kinase B/Akt at a glance (2005) (337)
- Protein Kinase Bα/Akt1 Regulates Placental Development and Fetal Growth* (2003) (332)
- NDR kinases regulate essential cell processes from yeast to humans (2006) (327)
- Differential Inhibition and Posttranslational Modification of Protein Phosphatase 1 and 2A in MCF7 Cells Treated with Calyculin-A, Okadaic Acid, and Tautomycin* (1997) (310)
- Physiological functions of protein kinase B/Akt. (2004) (305)
- Stabilization of Mdm2 via Decreased Ubiquitination Is Mediated by Protein Kinase B/Akt-dependent Phosphorylation* (2004) (302)
- Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation In Vivo (2007) (299)
- PI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis (2012) (292)
- Physiological roles of PKB/Akt isoforms in development and disease. (2007) (292)
- Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase (1999) (269)
- Life with a Single Isoform of Akt: Mice Lacking Akt2 and Akt3 Are Viable but Display Impaired Glucose Homeostasis and Growth Deficiencies (2006) (268)
- Carboxyl-Terminal Modulator Protein (CTMP), a Negative Regulator of PKB/Akt and v-Akt at the Plasma Membrane (2001) (260)
- 90-kDa Ribosomal S6 Kinase Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Protein Kinase-1* (1999) (256)
- Inhibition of protein kinase B/Akt. implications for cancer therapy. (2002) (246)
- p21-activated Kinase (PAK1) Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Kinase-1 (PDK1)* (2000) (242)
- Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. (1998) (238)
- PKB/Akt-dependent regulation of cell motility. (2013) (235)
- alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. (1990) (234)
- PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. (2005) (232)
- Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors (1992) (230)
- Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway. (2010) (229)
- PKB and the mitochondria: AKTing on apoptosis. (2008) (225)
- Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation* (2000) (225)
- Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. (2001) (220)
- AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer (2011) (220)
- A Human Protein Kinase Bγ with Regulatory Phosphorylation Sites in the Activation Loop and in the C-terminal Hydrophobic Domain* (1999) (216)
- Living with Lethal PIP3 Levels: Viability of Flies Lacking PTEN Restored by a PH Domain Mutation in Akt/PKB (2002) (213)
- PIKKing on PKB: regulation of PKB activity by phosphorylation. (2009) (213)
- Essential role of protein kinase Bγ (PKBγ/Akt3) in postnatal brain development but not in glucose homeostasis (2005) (213)
- The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase (1993) (212)
- Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. (1998) (211)
- Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes. (2012) (205)
- Protein kinase B alpha/Akt1 regulates placental development and fetal growth. (2003) (202)
- Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform. (1991) (201)
- Purification of glycogen synthase kinase 3 from rabbit skeletal muscle. Copurification with the activating factor (FA) of the (Mg-ATP) dependent protein phosphatase. (1981) (197)
- Dosage-Dependent Effects of Akt1/Protein Kinase Bα (PKBα) and Akt3/PKBγ on Thymus, Skin, and Cardiovascular and Nervous System Development in Mice (2005) (189)
- cAMP stimulates protein kinase B in a Wortmannin‐insensitive manner (1997) (189)
- Identification of a Plasma Membrane Raft-Associated PKB Ser473 Kinase Activity that Is Distinct from ILK and PDK1 (2002) (188)
- Molecular cloning of a second form of rac protein kinase. (1991) (179)
- Only Akt1 Is Required for Proliferation, while Akt2 Promotes Cell Cycle Exit through p21 Binding (2006) (178)
- Protein Kinase B Localization and Activation Differentially Affect S6 Kinase 1 Activity and Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 Phosphorylation (1999) (176)
- Apoptosis Suppression by Raf-1 and MEK1 Requires MEK- and Phosphatidylinositol 3-Kinase-Dependent Signals (2001) (175)
- The catalytic subunit of protein phosphatase 2A is carboxyl-methylated in vivo. (1994) (171)
- The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. (2006) (167)
- GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma (2009) (162)
- NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis (2008) (162)
- Hyperosmotic Stress Stimulates Promoter Activity and Regulates Cellular Utilization of the Serum- and Glucocorticoid-inducible Protein Kinase (Sgk) by a p38 MAPK-dependent Pathway* (2000) (160)
- Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae. (1981) (159)
- Calcium regulation of Ndr protein kinase mediated by S100 calcium‐binding proteins (1998) (156)
- G-Protein-coupled Receptors and Fcγ-receptors Mediate Activation of Akt/Protein Kinase B in Human Phagocytes* (1997) (156)
- Regulation of NDR Protein Kinase by Hydrophobic Motif Phosphorylation Mediated by the Mammalian Ste20-Like Kinase MST3 (2005) (155)
- Reconstitution of a Mg‐ATP‐dependent protein phosphatase and its activation through a phosphorylation mechanism (1982) (153)
- The ARE‐dependent mRNA‐destabilizing activity of BRF1 is regulated by protein kinase B (2004) (151)
- Insulin-stimulated Protein Kinase B Phosphorylation on Ser-473 Is Independent of Its Activity and Occurs through a Staurosporine-insensitive Kinase* (2001) (150)
- cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue. (1991) (148)
- Differential methylation and altered conformation of cytoplasmic and nuclear forms of protein phosphatase 2A during cell cycle progression (1995) (147)
- The MgATP-dependent protein phosphatase and protein phosphatase 1 have identical substrate specificities. (2005) (145)
- Constitutive activation of protein kinase B and phosphorylation of p47 phox by a membrane-targeted phosphoinositide 3-kinase (1996) (142)
- Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A. (1987) (142)
- Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation (2000) (141)
- A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways. (1992) (140)
- Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing. (1993) (140)
- Ligation of the T cell co‐stimulatory receptor CD28 activates the serine‐threonine protein kinase protein kinase B (1997) (139)
- Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle (1982) (137)
- Mechanism of Activation of NDR (Nuclear Dbf2-related) Protein Kinase by the hMOB1 Protein* (2004) (135)
- Phosphorylation of the type-II regulatory subunit of cyclic-AMP-dependent protein kinase by glycogen synthase kinase 3 and glycogen synthase kinase 5. (2005) (134)
- Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice. (2005) (133)
- Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle. (1982) (132)
- Differential Regulation by Calcium Reveals Distinct Signaling Requirements for the Activation of Akt and p70S6k * (1998) (126)
- MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-β signaling pathway in human glioblastoma. (2011) (125)
- PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage (2010) (124)
- Protein Kinase B β/Akt2 Plays a Specific Role in Muscle Differentiation* (2001) (121)
- Mechanism of protein kinase B activation by insulin/insulin-like growth factor-1 revealed by specific inhibitors of phosphoinositide 3-kinase--significance for diabetes and cancer. (1999) (121)
- Inactivation and dephosphorylation of protein kinase Bα (PKBα) promoted by hyperosmotic stress (1998) (119)
- NDR family of AGC kinases – essential regulators of the cell cycle and morphogenesis (2003) (118)
- Identification of Tyrosine Phosphorylation Sites on 3-Phosphoinositide-dependent Protein Kinase-1 and Their Role in Regulating Kinase Activity* (2001) (118)
- Domain Swapping Used To Investigate the Mechanism of Protein Kinase B Regulation by 3-Phosphoinositide-Dependent Protein Kinase 1 and Ser473 Kinase (1999) (118)
- Functional Characterization of Human RSK4, a New 90-kDa Ribosomal S6 Kinase, Reveals Constitutive Activation in Most Cell Types* (2005) (115)
- Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex (1999) (114)
- Human NDR Kinases Are Rapidly Activated by MOB Proteins through Recruitment to the Plasma Membrane and Phosphorylation (2005) (113)
- Osmotic Shock Inhibits Insulin Signaling by Maintaining Akt/Protein Kinase B in an Inactive Dephosphorylated State (1999) (112)
- The catalytic subunits of protein phosphatase-1 and protein phosphatase 2A are distinct gene products. (1984) (112)
- Characterisation of a reconstituted Mg-ATP-dependent protein phosphatase. (1983) (111)
- Ndr Protein Kinase Is Regulated by Phosphorylation on Two Conserved Sequence Motifs* (1999) (110)
- The MST1 and hMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation (2009) (110)
- Direct Identification of Tyrosine 474 as a Regulatory Phosphorylation Site for the Akt Protein Kinase* 210 (2002) (109)
- Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. (1994) (109)
- Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55. (1999) (106)
- Sphingosine Is a Novel Activator of 3-Phosphoinositide-dependent Kinase 1* (2000) (106)
- Centrosome-associated NDR kinase regulates centrosome duplication. (2007) (106)
- 12-O-Tetradecanoylphorbol-13-acetate-induced Dephosphorylation of Protein Kinase Cα Correlates with the Presence of a Membrane-associated Protein Phosphatase 2A Heterotrimer* (1996) (104)
- Translation regulation as a therapeutic target in cancer. (2012) (102)
- Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes. (1991) (101)
- Serum and Glucocorticoid-Responsive Kinase-1 Regulates Cardiomyocyte Survival and Hypertrophic Response (2005) (101)
- Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET (2012) (101)
- NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium (2015) (100)
- Human NDR Kinases Control G1/S Cell Cycle Transition by Directly Regulating p21 Stability (2011) (99)
- The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death (2009) (99)
- Structure of the Ca2+/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase. (2003) (96)
- Mechanism of Ca2+-mediated Regulation of NDR Protein Kinase through Autophosphorylation and Phosphorylation by an Upstream Kinase* (2003) (91)
- Regulation of protein kinase B. (1999) (90)
- Pyk2- and Src-Dependent Tyrosine Phosphorylation of PDK1 Regulates Focal Adhesions (2003) (89)
- Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development. (2010) (89)
- Neurofilament-associated protein phosphatase 2A: its possible role in preserving neurofilaments in filamentous states. (1995) (88)
- Promiscuous affairs of PKB/AKT isoforms in metabolism (2011) (88)
- Tissue‐specific expression of mRNAs encoding α‐ and β‐catalytic subunits of protein phosphatase 2A (1988) (87)
- PKBα is required for adipose differentiation of mouse embryonic fibroblasts (2006) (85)
- The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits. (1996) (84)
- Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling (2009) (84)
- Regulation of NDR2 Protein Kinase by Multi-site Phosphorylation and the S100B Calcium-binding Protein* (2004) (82)
- Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase. (1995) (80)
- Analysis of subunit isoforms in protein phosphatase 2A holoenzymes from rabbit and Xenopus. (1993) (79)
- Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage (2005) (78)
- The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C. (2001) (77)
- Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A (1995) (77)
- Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats. (1988) (77)
- The catalytic subunit of protein phosphatase 2A associates with the translation termination factor eRF1. (1996) (76)
- Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae. (1990) (76)
- Mammalian NDR protein kinases: from regulation to a role in centrosome duplication. (2008) (73)
- Modulation of the enzymatic properties of protein phosphatase 2A catalytic subunit by the recombinant 65-kDa regulatory subunit PR65alpha. (1997) (73)
- In Vivo Analysis of Protein Kinase B (PKB)/Akt Regulation in DNA-PKcs-null Mice Reveals a Role for PKB/Akt in DNA Damage Response and Tumorigenesis* (2008) (73)
- Ablation of the Kinase NDR1 Predisposes Mice to the Development of T Cell Lymphoma (2010) (71)
- Pleckstrin homology (PH) domains in signal transducton (1994) (70)
- MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas. (2014) (70)
- Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme (2013) (69)
- Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways. (2012) (69)
- Functional Expression of Human PP2Ac in Yeast Permits the Identification of Novel C-terminal and Dominant-negative Mutant Forms* (1999) (69)
- Regulation of 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) by Src Involves Tyrosine Phosphorylation of PDK1 and Src Homology 2 Domain Binding* (2008) (68)
- Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death. (2009) (68)
- UPDATE: PH Domains--A Universal Membrane Adapter (1997) (68)
- cAMP synthesis and degradation by phagosomes regulate actin assembly and fusion events: consequences for mycobacteria (2006) (68)
- Alternative Splicing Controls Myotonic Dystrophy Protein Kinase Structure, Enzymatic Activity, and Subcellular Localization (2003) (68)
- Differential NDR/LATS Interactions with the Human MOB Family Reveal a Negative Role for Human MOB2 in the Regulation of Human NDR Kinases (2010) (67)
- Integrated Akt/PKB signaling in immunomodulation and its potential role in cancer immunotherapy. (2015) (65)
- Differential Effects of Protein Kinase B/Akt Isoforms on Glucose Homeostasis and Islet Mass (2009) (63)
- AKT-ions with a TWIST between EMT and MET (2016) (62)
- PKB/Akt-dependent regulation of inflammation in cancer. (2017) (62)
- Identification of the residues on cyclic GMP-dependent protein kinase that are autophosphorylated in the presence of cyclic AMP and cyclic GMP. (1984) (61)
- cAMP mediated proteolysis of the catalytic subunit of cAMP‐dependent protein kinase (1986) (61)
- Update: PtdIns(3,4,5)P3 Gets Its Message Across (1997) (61)
- PH domains and phospholipases--a meaningful relationship? (1994) (61)
- Downstream of human NDR kinases: Impacting on c-myc and p21 protein stability to control cell cycle progression (2011) (60)
- Involvement of the Pleckstrin Homology Domain in the Insulin-stimulated Activation of Protein Kinase B* (1998) (60)
- Developmental Regulation of Expression and Activity of Multiple Forms of the Drosophila RAC Protein Kinase (*) (1995) (60)
- Control of Glycogen Synthesis in Cultured Human Muscle Cells* (1999) (60)
- The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility (2015) (59)
- Epithelium-Mesenchyme Interactions Control the Activity of Peroxisome Proliferator-Activated Receptor β/δ during Hair Follicle Development (2005) (59)
- The Akt/PKB pathway is constitutively activated in Theileria‐transformed leucocytes, but does not directly control constitutive NF‐κB activation (2001) (58)
- Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons (1999) (58)
- Isolation, characterization, and chromosomal localization of the porcine calcitonin receptor gene. Identification of two variants of the receptor generated by alternative splicing. (1994) (57)
- DNA-dependent Protein Kinase-mediated Phosphorylation of Protein Kinase B Requires a Specific Recognition Sequence in the C-terminal Hydrophobic Motif* (2009) (57)
- Deregulation of Translational Control of the 65-kDa Regulatory Subunit (PR65α) of Protein Phosphatase 2A Leads to Multinucleated Cells (*) (1995) (57)
- Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes (2008) (56)
- Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A (2002) (56)
- S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt. (2012) (55)
- Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells. (1998) (55)
- The PI3K-PKB/Akt pathway. (2015) (52)
- Human cytomegalovirus carries serine/threonine protein phosphatases PP1 and a host-cell derived PP2A (1996) (52)
- Acquired Resistance to Clinical Cancer Therapy: A Twist in Physiological Signaling. (2016) (52)
- Isolation of a cDNA and characterization of the 5' flanking region of the gene encoding the type I regulatory subunit of the cAMP-dependent protein kinase. (1987) (52)
- Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation. (2010) (51)
- PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts. (2006) (50)
- Two Splice Variants of Protein Kinase Bγ Have Different Regulatory Capacity Depending on the Presence or Absence of the Regulatory Phosphorylation Site Serine 472 in the Carboxyl-terminal Hydrophobic Domain* (2001) (50)
- RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1. (2003) (49)
- Gonadotropin-Releasing Hormone and Pituitary Adenylate Cyclase-Activating Polypeptide Affect Levels of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase A (PKA) Subunits in the Clonal Gonadotrope αT3-1 Cells: Evidence for Cross-Talk between PKA and Protein Kinase C Pathways. (1997) (49)
- Ultrastructural localization of the regulatory (RII) subunit of cyclic AMP-dependent protein kinase to subcellular compartments active in endocytosis and recycling of membrane receptors. (1990) (47)
- Protein kinase B/Akt is activated by polyomavirus middle-T antigen via a phosphatidylinositol 3-kinase-dependent mechanism (1998) (47)
- Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila. (1992) (47)
- Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae (2000) (47)
- PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage (2009) (46)
- Acyl Coenzyme A Thioesterase Them5/Acot15 Is Involved in Cardiolipin Remodeling and Fatty Liver Development (2012) (46)
- Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy. (2016) (45)
- Negative Regulation of ERK and Elk by Protein Kinase B Modulates c-fos Transcription* (2003) (44)
- The interconversion of protein phosphatase 2A between PP2A1 and PP2A0 during retinoic acid-induced granulocytic differentiation and a modification on the catalytic subunit in S phase of HL-60 cells. (1997) (44)
- Activation of Protein Kinase B Induced by H2O2 and Heat Shock through Distinct Mechanisms Dependent and Independent of Phosphatidylinositol 3-Kinase. (1999) (44)
- Deregulated signalling networks in human brain tumours. (2010) (44)
- Active-site mutations impairing the catalytic function of the catalytic subunit of human protein phosphatase 2A permit baculovirus-mediated overexpression in insect cells. (2001) (43)
- Phosphatidylinositol 3-Kinase Signaling in Thymocytes: The Need for Stringent Control (2010) (42)
- PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis (2014) (41)
- The PR55 and PR65 subunits of protein phosphatase 2A from Xenopus laevis. molecular cloning and developmental regulation of expression. (1995) (41)
- Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry (2012) (40)
- Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations (2013) (40)
- Protein kinases, from B to C. (2007) (40)
- Role of protein phosphatase 2A in the regulation of mitogen-activated protein kinase activity in ventricular cardiomyocytes. (1996) (39)
- Deltex-1 Activates Mitotic Signaling and Proliferation and Increases the Clonogenic and Invasive Potential of U373 and LN18 Glioblastoma Cells and Correlates with Patient Survival (2013) (39)
- Constitutively Active Protein Kinase B Enhances Lck and Erk Activities and Influences Thymocyte Selection and Activation1 (2003) (39)
- All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear (2015) (38)
- Regulation of Saccharomyces cerevisiae nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase by proteolysis during carbon starvation (1979) (38)
- Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. (2006) (38)
- Transcriptional regulation of a plasminogen activator gene by cyclic AMP in a homologous cell-free system. Involvement of cyclic AMP-dependent protein kinase in transcriptional control. (1988) (37)
- The 55 kDa regulatory subunit of protein phosphatase 2A plays a role in the activation of the HPV16 long control region in human cells with a deletion in the short arm of chromosome 11. (1992) (36)
- Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes. (2004) (36)
- Pleckstrin Homology (PH) Domains In Signal Transduction (1999) (36)
- Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis. (2009) (35)
- The Akt1 isoform is an essential mediator of ischaemic preconditioning (2012) (35)
- Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that sensitizes cells to apoptosis. (2009) (34)
- Okadaic acid-dependent induction of the urokinase-type plasminogen activator gene associated with stabilization and autoregulation of c-Jun. (1994) (34)
- Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development. (2005) (34)
- The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2Aα catalytic subunit (1988) (34)
- Deletion of PKBα/Akt1 Affects Thymic Development (2007) (34)
- Expression of the catalytic and regulatory subunits of protein phosphatase type 2A may be differentially modulated during retinoic acid-induced granulocytic differentiation of HL-60 cells. (1994) (33)
- PH domains--a universal membrane adapter. (1997) (33)
- Phosphorylation and proteolysis regulate the NAD‐dependent glutamate dehydrogenase from Saccharomyces cerevisiae (1980) (33)
- Multiple mRNA species code for the catalytic subunit of the cAMP-dependent protein kinase from LLC-PK1 cells. Evidence for two forms of the catalytic subunit. (1987) (32)
- Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development (2015) (32)
- Phosphorylation of NAD-dependent glutamate dehydrogenase from yeast. (1978) (32)
- SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment (2018) (29)
- Evidence for the Degradation of Nicotinamide Adenine Dinucleotide Phosphate-Dependent Glutamate Dehydrogenase of Candida utilis During Rapid Enzyme Inactivation (1978) (29)
- Modulation of regulatory and catalytic subunit levels of cAMP-dependent protein kinase A in anterior pituitary cells in response to direct activation of protein kinases A and C or after GnRH stimulation. (1995) (28)
- Tissue-specific expression of mRNAs encoding alpha- and beta-catalytic subunits of protein phosphatase 2A. (1988) (28)
- Purification and properties of the phospho and dephospho forms of yeast NAD-dependent glutamate dehydrogenase. (1980) (27)
- PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage. (2013) (27)
- TAZ-mediated crosstalk between Wnt and Hippo signaling. (2010) (27)
- cAMP-dependent protein kinase regulates renal epithelial cell properties. (1991) (26)
- Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide (2002) (26)
- Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively. (1993) (26)
- Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo (2012) (26)
- In Vitro and In Vivo Studies of a Naturally Occurring Variant of the Human p85α Regulatory Subunit of the Phosphoinositide 3-Kinase Inhibition of Protein Kinase B and Relationships With Type 2 Diabetes, Insulin Secretion, Glucose Disappearance Constant, and Insulin Sensitivity (2001) (26)
- Isolation of a mutant LLC-PK1 cell line defective in hormonal responsiveness. A pleiotropic lesion in receptor function. (1986) (26)
- NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development (2015) (25)
- The PR55 and PR65 Subunits of Protein Phosphatase 2A from Xenopus laevis (1995) (25)
- Activation of protein kinase B induced by H(2)O(2) and heat shock through distinct mechanisms dependent and independent of phosphatidylinositol 3-kinase. (1999) (25)
- Phosphorylation of basic helix-loop-helix transcription factor Twist in development and disease. (2012) (25)
- Correspondence analysis of microarray time-course data in case-control design (2004) (25)
- Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3). (2010) (24)
- The regulation of glutamate metabolism in Candida utilis. Evidence for two interconvertible forms of NAD-dependent glutamate dehydrogenase. (1977) (24)
- The phospho-opsin phosphatase from bovine rod outer segments. An insight into the mechanism of stimulation of type-2A protein phosphatase activity by protamine. (1994) (24)
- Expression cloning of a cDNA encoding the type II regulatory subunit of the cAMP‐dependent protein kinase (1986) (23)
- PKB/Akt interacts with inosine‐5′ monophosphate dehydrogenase through its pleckstrin homology domain (2000) (22)
- Proteolytic inactivation of the NADP-dependent glutamate dehydrogenase in proteinase-deficient mutants of Saccharomyces cerevisiae. (1980) (22)
- The Hemodynamic Basis for Positional- and Inter-Fetal Dependent Effects in Dual Arterial Supply of Mouse Pregnancies (2012) (22)
- Effect of hypothyroidism and thyroid hormone replacement on the level of protein kinase C and protein kinase A in rat liver (1991) (21)
- Signal transduction: What goes up must come down (1998) (21)
- Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation (2006) (21)
- Survival and Size Are Differentially Regulated by Placental and Fetal PKBalpha/AKT1 in Mice1 (2011) (21)
- Regulation of cAMP-dependent protein kinase in cultured cells. (1985) (20)
- Phosphatidylinositol 3-Kinase Confers Resistance to Encephalomyocarditis and Herpes Simplex Virus-Induced Cell Death Through the Activation of Distinct Downstream Effectors1 (2001) (20)
- Chronic Akt1 Deficiency Attenuates Adverse Remodeling and Enhances Angiogenesis After Myocardial Infarction (2013) (19)
- Eukaryotic translation termination factor 1 associates with protein phosphatase 2A and targets it to ribosomes. (1999) (19)
- Important role for phylogenetically invariant PP2Acalpha active site and C-terminal residues revealed by mutational analysis in Saccharomyces cerevisiae. (2000) (18)
- Blocking Akt-ivity (2009) (18)
- Characterization of two mutants of the LLC-PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP-dependent protein kinase. (1987) (18)
- hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme. (2014) (18)
- Phosphorylation of the Twist1-Family Basic Helix-Loop-Helix Transcription Factors Is Involved in Pathological Cardiac Remodeling (2011) (17)
- From man to mouse and back again: advances in defining tumor AKTivities in vivo (2010) (17)
- LLC‐PK1 cell mutants in cAMP metabolism respond normally to phorbol esters (1986) (17)
- Interaction of nucleoredoxin with protein phosphatase 2A (2006) (16)
- Analysis of protein kinase B/Akt. (2002) (16)
- PI 3 K rescues the detrimental effects of chronic Akt activation in the heart during ischemia / reperfusion injury (2018) (16)
- Biochemical characterization of recombinant subunits of type 2A protein phosphatase overexpressed in Pichia pastoris. (2000) (16)
- Residues 36‐42 of liver RNase PL3 contribute to its uridine‐preferring substrate specificity. Cloning of the cDNA and site‐directed mutagenesis studies (1994) (16)
- Cell polarity: Scaffold proteins par excellence (2000) (16)
- The Carboxy-Terminal Modulator Protein (CTMP) Regulates Mitochondrial Dynamics (2009) (16)
- Mechanisms of cAMP-mediated gene induction: examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase. (1991) (15)
- Reactivation of the phospho form of the NAD-dependent glutamate dehydrogenase by a yeast protein phosphatase. (1981) (15)
- Melatonin Synthesis in the Bovine Pineal Gland Is Regulated by Type II Cyclic AMP‐Dependent Protein Kinase (1997) (15)
- Activation of cAMP-dependent protein kinase alters the chromatin structure of the urokinase-type plasminogen activator gene promoter. (1994) (15)
- Role of protein phosphatase 2A in Drosophila development. (1995) (15)
- Bone vascularization and trabecular bone formation are mediated by PKBalpha/Akt1 in a gene‐dosage‐dependent manner: In vivo and ex vivo MRI (2010) (14)
- Overcoming resistance to rapalogs in gliomas by combinatory therapies. (2013) (14)
- Meeting Report: Targeting the Kinome—20 Years of Tyrosine Kinase Inhibitor Research in Basel (2007) (14)
- Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein (2009) (13)
- Role of PKB/Akt in Liver Diseases (2010) (13)
- The 10q25.3-26.1 G protein-coupled receptor gene GPR26 is epigenetically silenced in human gliomas. (2009) (13)
- Developmental expression of the RI subunit of cyclic AMP-dependent protein kinase in retina. (1989) (13)
- cAMP‐dependent protein kinase activation affects vasopressin V2‐receptor number and internalization in LLC‐PK1 renal epithelial cells (1991) (12)
- Overexpression of the alpha-type protein kinase (PK) C in LLC-PK1 cells does not lead to a proportional increase in the induction of two 12-O-tetradecanoylphorbol-13-acetate-inducible genes. (1991) (12)
- Pathway of urokinase-type plasminogen activator induction in the T47D and LLC-PK1 cell lines. (1987) (11)
- In vitro and in vivo studies of a naturally occurring variant of the human p85alpha regulatory subunit of the phosphoinositide 3-kinase: inhibition of protein kinase B and relationships with type 2 diabetes, insulin secretion, glucose disappearance constant, and insulin sensitivity. (2001) (11)
- Dependence of urokinase-type-plasminogen-activator induction on cyclic AMP-dependent protein kinase activation in LLC-PK1 cells. (1987) (11)
- Cobalamins and cobalamin-dependent enzymes in Candida utilis (1979) (11)
- Protein phosphatases on the piste (1996) (11)
- Long-term stimulation of cAMP production in LLC-PK1 pig kidney epithelial cells by salmon calcitonin or a photoactivatable analogue of vasopressin. (1987) (11)
- Multimodal imaging reveals a role for Akt1 in fetal cardiac development (2013) (11)
- Classification of Protein Phosphatases Involved in Cellular Regulation (1981) (10)
- In search of signaling pathways critical for ovarian graft reception: Akt1 is essential for long-term survival of ovarian grafts. (2014) (10)
- Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. (2008) (10)
- by Cyclic AMP-Dependent Protein Kinase Mechanism of Protein Kinase B Activation (1999) (9)
- mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition. (2017) (9)
- Complementation between LLC-PK1 mutants affected in polypeptide hormone-receptor function. (1987) (9)
- Staurosporine stimulates expression of the urokinase‐type (u‐PA) plasminogen activator in LLC‐PK1 cells (1989) (9)
- The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A alpha catalytic subunit. (1988) (9)
- Targeting the Kinome II. (2009) (8)
- The mechanism, role and control of the inactivation of glutamate dehydrogenases in yeast. (1982) (8)
- mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition (2017) (8)
- AGC kinases in cancer metastasis, immune checkpoint regulation and drug resistance. (2018) (7)
- K inhibition renders cardiac protection against myocardial infarction through PDK 1 phosphorylation of Akt (2011) (7)
- Phosphorylation of K-casein by glycogen synthase kinase-3 from rabbit skeletal muscle. (1983) (7)
- Expression and organization of protein phosphatase 2A catalytic subunit genes. (1990) (7)
- Large-scale expression and purification of a soluble form of the pleckstrin homology domain of the human protooncogenic serine/threonine protein kinase PKB (c-akt) in Escherichia coli. (1999) (6)
- A novel expression system for Gs-coupled receptors. (1993) (6)
- PromoterPlot: a graphical display of promoter similarities by pattern recognition (2005) (6)
- Abnormal expression of the RI subunit of cyclic AMP-dependent protein kinase in Y-79 retinoblastoma cells. (1989) (6)
- Characterization of fragmented 3-phosphoinsitide-dependent protein kinase-1 (PDK1) by phosphosite-specific antibodies. (2013) (6)
- Pleckstrin homology domains. (1995) (6)
- cAMP metabolism in the porcine kidney epithelial cell line LLC-PK1: the central role of the cAMP-dependent protein kinase in cAMP-mediated gene induction. (1988) (6)
- Gonadotropin-releasing hormone and pituitary adenylate cyclase-activating polypeptide affect levels of cyclic adenosine 3',5'-monophosphate-dependent protein kinase A (PKA) subunits in the clonal gonadotrope alphaT3-1 cells: evidence for cross-talk between PKA and protein kinase C pathways. (1997) (5)
- Expression and purification of the human thrombin receptor. (1998) (5)
- Tethering, targeting and triggering of protein phosphatases. (1994) (5)
- Mechanism of protein kinase B activation by insulin IGF1 revealed by specific inhibitors of the phosphoinositide 3-kinase. Significance for diabetes and cancer (1998) (5)
- Reduced hepatic lipid content in Pten‐haplodeficient mice because of enhanced AKT2/PKBβ activation in skeletal muscle (2015) (3)
- Erratum: PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury (Journal of Clinical Investigation (2005) 115 (2128-2138) DOI: 10.1172/JCI23073) (2006) (3)
- A novel LLC-PK1 renal epithelial cell mutant impaired in in vivo down-regulation of cAMP-mediated hormonal response. (1991) (3)
- The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit. (1988) (3)
- Reduced PP 2 A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice (2001) (2)
- PROTEIN PHOSPHORYLATION AND THE NEURAL AND HORMONAL CONTROL OF ENZYME ACTIVITY1 (1983) (2)
- Structure, Regulation and Targeting of Protein Phosphatase 2A (1997) (2)
- Codominant expression of a mutation affecting the cAMP-dependent protein kinase catalytic subunit in somatic cell hybrids of LLC-PK1 cells. (1988) (2)
- PH domain of serine-threonine protein kinase B (RAC-PKB). Expression and binding assay for phosphoinositides and inositol phosphates. (1998) (2)
- RAC: RAC PK (vertebrates and D. melanogaster) (akt, PKB) (1995) (2)
- an Inhibitor of Protein Kinase C Target for the Anticancer and Radiosensitizing Agent PKC 412 ,-Kinase / Akt Survival Pathway Is a ′ The Phosphatidylinositide 3 Updated (2001) (2)
- Tumor and Stem Cell Biology MAP Kinase-Interacting Kinase 1 Regulates SMAD 2-Dependent TGF-b Signaling Pathway in HumanGlioblastoma (2011) (2)
- A BamHI RFLP at the locus encoding the 65-kDa regulatory subunit of porcine protein phosphatase 2A (PPP2ARB). (2009) (1)
- Protein kinases in high grade glioma: Towards therapeutic concoctions (2012) (1)
- Chronic Akt 1 Deficiency Attenuates Adverse Remodeling and Enhances Angiogenesis After Myocardial Infarction (1)
- Molecular Complexity of Protein Phosphatase 2A Holoenzymes and Delineation of their Function (1993) (1)
- Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes [Erratum to document cited in CA114(3):18572v] (1991) (1)
- Faculty Opinions recommendation of Intracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine models. (2011) (1)
- Novel individual metabolic profile characterizes the protein kinase B-alpha (pkbα−/−) in vivo model (2014) (1)
- RFLPs at the porcine locus encoding the type I-alpha regulatory subunit of the cAMP-dependent protein kinase (PRKAR1A). (2009) (1)
- Primary structure of protein phosphatase 2A as determined by molecular cloning: implications for a protein phosphatase gene family. (1988) (1)
- Downstream Effectors Through the Activation of Distinct Herpes Simplex Virus-Induced Cell Death Resistance to Encephalomyocarditis and Phosphatidylinositol 3-Kinase Confers (2001) (0)
- Protein Kinase B (cid:1) /Akt1 Regulates Placental Development and Fetal Growth* □ S (2003) (0)
- Structure of PKB kinase domain (2003) (0)
- Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP (2002) (0)
- Method for activating a kinase. (1996) (0)
- Multimodal imaging reveals a role for Akt1 in fetal cardiovascular development (2014) (0)
- Detection of heterologous Gs-coupled receptor activity in LLC-PK1 cells based on expression of urokinase-type plasminogen activator. (1997) (0)
- Molecular and Cellular Pathobiology hMOB 3 Modulates MST 1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme (2014) (0)
- Results Reduced Cardiac Function and Altered Morphology in Adult Akt 1-Deficient Mice (0)
- Correction: Single electrons in silicon drops (1998) (0)
- Faculty Opinions recommendation of Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1. (2010) (0)
- Identification of substrates of protein phosphatase 2A in synchronously cycling fibroblasts (1997) (0)
- OE-070 Serum and Glucocorticoid-responsive Kinase Regulates Cardiomyocyte Survival and Hypertrophy(Cell death, apoptosis/necrosis (M) OE12,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (0)
- Mutantdefective inprocessing ofanenzymelocated inthe lysosome-like vacuole ofSaccharomyces cerevisiae (1981) (0)
- Abstract LB-169: Dissecting signaling pathways regulating translation in human glioblastoma (2011) (0)
- Use of protein kinase inhibitors to dissect the regulation of protein kinase B [PKB-Akt] by upstream kinases (2001) (0)
- Thymocyte Selection and Activation Lck and Erk Activities and Influences Constitutively Active Protein Kinase B Enhances (2016) (0)
- Tissue Origin and Microbial Stimulus T Cells Depend on + -Producing CD4 g IFN-Chemotactic Responses of IL-4-, IL-10-, and (2006) (0)
- Method for screening compounds that interact with protein kinase rac. (1996) (0)
- Faculty Opinions recommendation of Vimentin is a novel AKT1 target mediating motility and invasion. (2010) (0)
- Faculty Opinions recommendation of TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. (2011) (0)
- Traitement du cancer par modulation d’un mnk (2009) (0)
- Editorial overviewCell regulation (2005) (0)
- Crystal structure of human THEM5 (2012) (0)
- REGULATION OF PROTEIN KINASE B—IMPLICATIONS FOR INSULIN SIGNALING (2002) (0)
- DEV119016 732..742 (2015) (0)
- CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA (1999) (0)
- Mutant defective in processing of a lysosome-like vacuole of Saccharom (proenzyme/posttranslational modification/proteinases/multiple hyd (2016) (0)
- Regulation of protein kinase B by DNA-dependant protein kinase (2005) (0)
- Solution structure of calcium loaded S100B complexed to a peptide from N-Terminal regulatory domain of NDR kinase. (2003) (0)
- Modulation of PI3K/PTEN Pathway Does Not Affect Catalytic Activity of PDK1 in Jurkat Cells. (2017) (0)
- Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging (2013) (0)
- Crystal structure of human THEM4 (2012) (0)
- protein serine / Tronina nuclear kinases. (1995) (0)
- Structure of protein kinase B unphosphorylated (2003) (0)
- PROTEIN KINASE B ( PKB / AKT ) – A COMMON ELEMENT IN MULTIPLE SIGNALING PATHWAYS INVOLVED IN INSULIN SIGNALING , CELL SURVIVALAND CANCER (2001) (0)
- Identification of a new member of the protein kinase family (1990) (0)
- Akt1 deficient mice show resistance to DSS-colitis induced leak of albumin-based contrast media from the colon vasculature (2010) (0)
- Vascular function and growth is differentially regulated by fetal and placental PKBalpha/Akt1 in a gene dosage dependent manner: Non-invasive dynamic contrast enhanced MRI (2009) (0)
- A process for the activation of a kinase (1996) (0)
- compartmentalization of tau in transgenic mice (2001) (0)
- The Protein Kinase B Family — Structure, Regulation and Function (1997) (0)
- Recombinant type I regulatory subunit of the cAMP‐dependent protein kinase is biologically active (1987) (0)
- Faculty Opinions recommendation of The effect Akt2 deletion on tumor development in Pten(+/-) mice. (2011) (0)
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What Schools Are Affiliated With Brian Arthur Hemmings?
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