B. Brett Finlay
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Why Is B. Brett Finlay Influential?
(Suggest an Edit or Addition)B. Brett Finlay's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gut microbiota in health and disease. (2010) (1760)
- Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. (2008) (1581)
- Common themes in microbial pathogenicity revisited (1997) (1528)
- Enteropathogenic E. coli (EPEC) Transfers Its Receptor for Intimate Adherence into Mammalian Cells (1997) (1218)
- Recent Advances in Understanding Enteric Pathogenic Escherichia coli (2013) (1049)
- Molecular mechanisms of Escherichia coli pathogenicity (2010) (982)
- Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. (2007) (964)
- Common themes in microbial pathogenicity. (1989) (816)
- Exploitation of mammalian host cell functions by bacterial pathogens. (1997) (789)
- Anti-Immunology: Evasion of the Host Immune System by Bacterial and Viral Pathogens (2006) (781)
- Soluble CD14 participates in the response of cells to lipopolysaccharide (1992) (746)
- The Intestinal Microbiome in Early Life: Health and Disease (2014) (674)
- Dissecting virulence: systematic and functional analyses of a pathogenicity island. (2004) (619)
- Shifting the balance: antibiotic effects on host–microbiota mutualism (2011) (595)
- Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications. (2012) (584)
- NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion (2014) (539)
- Murine Salmonellosis Studied by Confocal Microscopy: Salmonella typhimurium Resides Intracellularly Inside Macrophages and Exerts a Cytotoxic Effect on Phagocytes In Vivo (1997) (534)
- Type III Secretion Systems and Disease (2007) (521)
- Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa (2010) (511)
- Manipulation of host-cell pathways by bacterial pathogens (2007) (491)
- Quorum sensing in bacterial virulence. (2010) (464)
- Antibiotic-Induced Perturbations of the Intestinal Microbiota Alter Host Susceptibility to Enteric Infection (2008) (461)
- Salmonella pathogenicity islands: big virulence in small packages. (2000) (445)
- Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells (2001) (375)
- Assembly, structure, function and regulation of type III secretion systems (2017) (375)
- An anti-infective peptide that selectively modulates the innate immune response (2007) (374)
- Cytoskeletal rearrangements accompanying salmonella entry into epithelial cells. (1991) (374)
- The Human Microbiome and Child Growth - First 1000 Days and Beyond. (2019) (369)
- Citrobacter rodentium: infection, inflammation and the microbiota (2014) (364)
- Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake. (1992) (358)
- The gut microbiome in human neurological disease: A review (2017) (355)
- Tight junctions as targets of infectious agents. (2009) (343)
- Biogenesis of Salmonella typhimurium‐containing vacuoles in epithelial cells involves interactions with the early endocytic pathway (1999) (343)
- Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening (2003) (342)
- Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein. (1997) (339)
- Salmonella interactions with polarized human intestinal Caco-2 epithelial cells. (1990) (338)
- Pathogenicity islands: a molecular toolbox for bacterial virulence (2006) (330)
- Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to Exacerbated Citrobacter rodentium-Induced Colitis (2011) (329)
- Decreased shedding of Escherichia coli O157:H7 by cattle following vaccination with type III secreted proteins. (2004) (325)
- Crystal structure of enteropathogenic Escherichia coli intimin–receptor complex (2000) (318)
- Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens (2003) (313)
- Microbial pathogenesis and cytoskeletal function (2003) (306)
- Can innate immunity be enhanced to treat microbial infections? (2004) (301)
- Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells. (1993) (299)
- Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells (1996) (288)
- A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation. (1996) (288)
- Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. (2007) (287)
- The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen (2000) (287)
- Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replication. (1988) (281)
- Elimination of host cell PtdIns(4,5)P2 by bacterial SigD promotes membrane fission during invasion by Salmonella (2002) (278)
- EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells (1996) (271)
- Exploitation of host cells by enteropathogenic Escherichia coli. (2000) (270)
- Intracellular replication is essential for the virulence of Salmonella typhimurium. (1991) (270)
- Enterohemorrhagic Escherichia coliO157:H7 Produces Tir, Which Is Translocated to the Host Cell Membrane but Is Not Tyrosine Phosphorylated (1999) (264)
- Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells. (1995) (261)
- Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors (1995) (258)
- Typhoid fever and other salmonellosis: a continuing challenge. (1995) (255)
- Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract (1997) (245)
- Controlling the maturation of pathogen-containing vacuoles: a matter of life and death (1999) (244)
- Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents (2020) (243)
- Interactions between enteropathogenic Escherichia coli and host epithelial cells. (1997) (238)
- Effect of Antibiotic Treatment on the Intestinal Metabolome (2011) (237)
- Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. (2004) (235)
- In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits. (1991) (232)
- Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7 (2004) (232)
- The Salmonella Effector Protein SopB Protects Epithelial Cells from Apoptosis by Sustained Activation of Akt* (2005) (232)
- The caspase-1 inflammasome: a pilot of innate immune responses. (2008) (230)
- The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak (2012) (226)
- Locus of Enterocyte Effacement from Citrobacter rodentium: Sequence Analysis and Evidence for Horizontal Transfer among Attaching and Effacing Pathogens (2001) (225)
- Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayer (1988) (221)
- Salmonella enterica Serovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis (2005) (221)
- The invasion‐associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells (2002) (219)
- Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells (1992) (219)
- Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals (1999) (214)
- Perinatal antibiotic treatment affects murine microbiota, immune responses and allergic asthma (2013) (212)
- Host Susceptibility to the Attaching and Effacing Bacterial Pathogen Citrobacter rodentium (2003) (209)
- Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice (2003) (209)
- Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes. (1986) (208)
- Clearance of Citrobacter rodentium Requires B Cells but Not Secretory Immunoglobulin A (IgA) or IgM Antibodies (2004) (207)
- Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. (1989) (207)
- SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34 (2008) (202)
- Molecular Analysis as an Aid To Assess the Public Health Risk of Non-O157 Shiga Toxin-Producing Escherichia coli Strains (2008) (198)
- Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells (1992) (197)
- Attaching and effacing pathogen‐induced tight junction disruption in vivo (2006) (194)
- Salmonella typhimurium Infection and Lipopolysaccharide Stimulation Induce Similar Changes in Macrophage Gene Expression1 (2000) (194)
- The role of the intestinal microbiota in enteric infection (2009) (191)
- Structural characterization of the molecular platform for type III secretion system assembly (2005) (191)
- A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system (2009) (188)
- Activation of Akt/Protein Kinase B in Epithelial Cells by theSalmonella typhimurium Effector SigD* (2000) (184)
- M cells and the pathogenesis of mucosal and systemic infections. (1996) (184)
- Regulation of Type III Secretion Hierarchy of Translocators and Effectors in Attaching and Effacing Bacterial Pathogens (2005) (183)
- Characterization of the micro‐environment of Salmonella typhimurium–containing vacuoles within MDCK epithelial cells (1992) (181)
- Recruitment of Cytoskeletal and Signaling Proteins to Enteropathogenic and Enterohemorrhagic Escherichia coli Pedestals (2001) (177)
- Analysis of the Contribution of Salmonella Pathogenicity Islands 1 and 2 to Enteric Disease Progression Using a Novel Bovine Ileal Loop Model and a Murine Model of Infectious Enterocolitis (2005) (176)
- Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids (2017) (175)
- Salmonella type III effectors PipB and PipB2 are targeted to detergent‐resistant microdomains on internal host cell membranes (2003) (174)
- Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins (1996) (173)
- Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-gamma1 (1997) (173)
- Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function (2009) (173)
- Secretin of the Enteropathogenic Escherichia coli Type III Secretion System Requires Components of the Type III Apparatus for Assembly and Localization (2003) (173)
- Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems (2002) (171)
- Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer (1988) (171)
- Toll-Like Receptor 4 Contributes to Colitis Development but Not to Host Defense during Citrobacter rodentium Infection in Mice (2006) (170)
- Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. (2008) (170)
- SifA, a Type III Secreted Effector of Salmonella typhimurium, Directs Salmonella‐Induced Filament (Sif) Formation Along Microtubules (2002) (163)
- Altering Host Resistance to Infections through Microbial Transplantation (2011) (162)
- Human Response to Escherichia coliO157:H7 Infection: Antibodies to Secreted Virulence Factors (2000) (161)
- Expression and Secretion of Salmonella Pathogenicity Island-2 Virulence Genes in Response to Acidification Exhibit Differential Requirements of a Functional Type III Secretion Apparatus and SsaL* (2004) (160)
- Disruption of the Salmonella-Containing Vacuole Leads to Increased Replication of Salmonella enterica Serovar Typhimurium in the Cytosol of Epithelial Cells (2002) (160)
- Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion (1999) (160)
- Microbial pathogenesis: Lipid rafts as pathogen portals (2000) (158)
- Salmonella: from Pathogenesis to Therapeutics (2006) (158)
- Pathogenic trickery: deception of host cell processes (2001) (157)
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. (2006) (156)
- Structural and biochemical characterization of the type III secretion chaperones CesT and SigE (2001) (155)
- A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlA (2005) (155)
- Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. (2004) (154)
- Mice Lacking T and B Lymphocytes Develop Transient Colitis and Crypt Hyperplasia yet Suffer Impaired Bacterial Clearance during Citrobacter rodentium Infection (2002) (153)
- The Intestinal Microbiota Plays a Role in Salmonella-Induced Colitis Independent of Pathogen Colonization (2011) (153)
- Enteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3‐kinase‐dependent pathways (2001) (152)
- High‐frequency intracellular invasion of epithelial cells by serotype M1 group A streptococci: M1 protein‐mediated invasion and cytoskeletal rearrangements (1999) (151)
- Typhoid fever--important issues still remain. (1998) (151)
- The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells (1994) (149)
- Bacterial pathogenesis: exploiting cellular adherence. (2003) (148)
- Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers (1993) (148)
- Translocated Intimin Receptor and Its Chaperone Interact with ATPase of the Type III Secretion Apparatus of Enteropathogenic Escherichia coli (2003) (148)
- Type III Secretion-Dependent Hemolytic Activity of Enteropathogenic Escherichia coli (1999) (148)
- The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. (2010) (147)
- Listeria monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-Activated Protein Kinase Pathway (1998) (147)
- Pathogenesis of enteric Salmonella infections (2008) (146)
- Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting (2017) (146)
- The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments. (1995) (145)
- Structural analysis of a prototypical ATPase from the type III secretion system (2007) (142)
- Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells (1996) (141)
- Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map) (2006) (141)
- Gut feelings: enteropathogenic E. coli (EPEC) interactions with the host. (2000) (140)
- Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell (1994) (139)
- Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection* (2012) (137)
- Salmonella typhimurium Virulence Genes Are Induced upon Bacterial Invasion into Phagocytic and Nonphagocytic Cells (1999) (135)
- Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS (2008) (133)
- The hygiene hypothesis: current perspectives and future therapies (2015) (129)
- Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. (2002) (128)
- Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson's Disease (2020) (128)
- Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis. (2008) (128)
- Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens (2007) (128)
- Phage display: applications, innovations, and issues in phage and host biology. (1998) (128)
- A synaptojanin‐homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activation (2001) (127)
- Toll-Like Receptor 4 Dependence of Innate and Adaptive Immunity to Salmonella: Importance of the Kupffer Cell Network 1 (2004) (127)
- Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection. (2006) (126)
- CesT is a multi‐effector chaperone and recruitment factor required for the efficient type III secretion of both LEE‐ and non‐LEE‐encoded effectors of enteropathogenic Escherichia coli (2005) (125)
- Characterization of Salmonella‐Induced Filaments (Sifs) Reveals a Delayed Interaction Between Salmonella‐Containing Vacuoles and Late Endocytic Compartments (2001) (125)
- Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells (1993) (124)
- Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine (2005) (124)
- A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells (1994) (123)
- Comparative studies of the amino acid and nucleotide sequences of pilin derived from Pseudomonas aeruginosa PAK and PAO (1985) (123)
- Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir‐based mechanism for pedestal formation (2001) (122)
- Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review (2019) (122)
- Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with α-actinin (2000) (121)
- Structural characterization of a type III secretion system filament protein in complex with its chaperone (2005) (121)
- Invasion and replication of Salmonella typhimurium in animal cells (1990) (120)
- Effect of cell polarization and differentiation on entry of Listeria monocytogenes into the enterocyte-like Caco-2 cell line (1996) (120)
- The Salmonella enterica Serovar Typhimurium Divalent Cation Transport Systems MntH and SitABCD Are Essential for Virulence in an Nramp1G169 Murine Typhoid Model (2004) (119)
- Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body (2016) (119)
- Role of acid tolerance response genes in Salmonella typhimurium virulence (1993) (118)
- Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. (2005) (117)
- Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside (2000) (116)
- Phytonutrient diet supplementation promotes beneficial Clostridia species and intestinal mucus secretion resulting in protection against enteric infection (2015) (115)
- Modulation of Inducible Nitric Oxide Synthase Expression by the Attaching and Effacing Bacterial Pathogen Citrobacter rodentium in Infected Mice (2002) (115)
- The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. (2007) (114)
- An α-Helical Cationic Antimicrobial Peptide Selectively Modulates Macrophage Responses to Lipopolysaccharide and Directly Alters Macrophage Gene Expression1 (2000) (113)
- Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria (1993) (112)
- Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases. (2015) (112)
- Role of EspB in Experimental Human EnteropathogenicEscherichia coli Infection (2000) (111)
- Molecular mechanisms of Salmonella virulence and host resistance. (2009) (109)
- The future of mucosal immunology: studying an integrated system-wide organ (2010) (109)
- A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. (2013) (109)
- Transcriptional Inhibitor of Virulence Factors in Enteropathogenic Escherichia coli (2005) (109)
- Phosphatases and kinases delivered to the host cell by bacterial pathogens. (2000) (107)
- Intracellular Delivery and Antibacterial Activity of Gentamicin Encapsulated in pH-Sensitive Liposomes (1998) (107)
- Crossing the Line: Selection and Evolution of Virulence Traits (2006) (106)
- Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells (1993) (105)
- Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. (2005) (105)
- Breastmilk Feeding Practices Are Associated with the Co-Occurrence of Bacteria in Mothers' Milk and the Infant Gut: the CHILD Cohort Study. (2020) (105)
- Salmonella enterica serovar Typhimurium effector SigD/SopB is membrane‐associated and ubiquitinated inside host cells (2002) (103)
- Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells. (1994) (103)
- Functional Expression of Nramp1 In Vitro in the Murine Macrophage Line RAW264.7 (1999) (103)
- Cloning and sequencing of the Pseudomonas aeruginosa PAK pilin gene (1985) (103)
- Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever. (2009) (102)
- Methods to study bacterial invasion (1993) (102)
- Macrophages Inhibit Salmonella Typhimurium Replication through MEK/ERK Kinase and Phagocyte NADPH Oxidase Activities* (2002) (101)
- Factors essential for the penetration of mammalian cells by Yersinia. (1988) (100)
- Identification of the intimin‐binding domain of Tir of enteropathogenic Escherichia coli (1999) (100)
- Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes (2002) (100)
- Salmonella interactions with host cells: in vitro to in vivo. (2000) (99)
- Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation (1994) (98)
- Symmetric infection of rotavirus on polarized human intestinal epithelial (Caco-2) cells (1991) (97)
- Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell (1997) (96)
- Cytopathic effects of Treponema denticola chymotrypsin-like proteinase on migrating and stratified epithelial cells (1995) (96)
- Enteropathogenic Escherichia coli: a pathogen that inserts its own receptor into host cells (1999) (96)
- Methicillin-resistant Staphylococcus aureus (MRSA) Pyruvate Kinase as a Target for Bis-indole Alkaloids with Antibacterial Activities* (2011) (95)
- Salmonella typhimurium induces an inositol phosphate flux in infected epithelial cells. (1992) (95)
- Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and p38 Mitogen-Activated Protein Kinase Activation (2011) (95)
- Evidence that Tight Junctions Are Disrupted Due to Intimate Bacterial Contact and Not Inflammation during Attaching and Effacing Pathogen Infection In Vivo (2006) (94)
- Nramp1 Modifies the Fusion of Salmonella typhimurium-containing Vacuoles with Cellular Endomembranes in Macrophages* (2002) (94)
- The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice (2004) (93)
- Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria (2012) (92)
- Segmented filamentous bacteria prevent colonization of enteropathogenic Escherichia coli O103 in rabbits. (2000) (92)
- Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. (2008) (91)
- Molecular and cellular mechanisms of Salmonella pathogenesis. (1994) (90)
- Listeriolysin O activates mitogen-activated protein kinase in eucaryotic cells (1996) (90)
- Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens. (2015) (90)
- Proteomic Analysis of the Intestinal Epithelial Cell Response to Enteropathogenic Escherichia coli* (2004) (89)
- Thinking bigger: How early‐life environmental exposures shape the gut microbiome and influence the development of asthma and allergic disease (2019) (89)
- Salmonella typhimurium induces selective aggregation and internalization of host cell surface proteins during invasion of epithelial cells. (1994) (88)
- Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway. (1998) (88)
- Invasive and Adherent Bacterial Pathogens Co-Opt Host Clathrin for Infection (2007) (87)
- Salmonella and apoptosis: to live or let die? (2001) (86)
- Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation. (1999) (86)
- Salmonella enterica Serovar Senftenberg Human Clinical Isolates Lacking SPI-1 (2008) (86)
- Comparison of Salmonella typhi and Salmonella typhimurium invasion, intracellular growth and localization in cultured human epithelial cells. (1994) (85)
- The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity (2013) (85)
- Aggregation via the Red, Dry, and Rough Morphotype Is Not a Virulence Adaptation in Salmonella enterica Serovar Typhimurium (2008) (85)
- Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies. (2020) (84)
- Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens (2012) (82)
- Quantitative Proteomic Analysis of Type III Secretome of Enteropathogenic Escherichia coli Reveals an Expanded Effector Repertoire for Attaching/Effacing Bacterial Pathogens* (2012) (82)
- SseK1 and SseK2 Are Novel Translocated Proteins of Salmonella enterica Serovar Typhimurium (2004) (82)
- Autophagy Facilitates Salmonella Replication in HeLa Cells (2014) (82)
- Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. (2002) (81)
- The rpoS-dependent starvation-stress response locus stiA encodes a nitrate reductase (narZYWV) required for carbon-starvation-inducible thermotolerance and acid tolerance in Salmonella typhimurium. (1999) (81)
- Bacterial avoidance of phagocytosis. (2002) (80)
- SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion (2007) (79)
- Enteric pathogen exploitation of the microbiota-generated nutrient environment of the gut. (2011) (78)
- The impact of gut microbes in allergic diseases (2012) (78)
- Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory (2013) (77)
- Immunosuppressive Treatment Alters Secretion of Ileal Antimicrobial Peptides and Gut Microbiota, and Favors Subsequent Colonization by Uropathogenic Escherichia coli (2017) (76)
- Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma. (2016) (75)
- The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling (2010) (75)
- Should the Human Microbiome Be Considered When Developing Vaccines? (2010) (75)
- Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment (2014) (75)
- Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin. (2000) (75)
- Bringing down the host: enteropathogenic and enterohaemorrhagic Escherichia coli effector‐mediated subversion of host innate immune pathways (2015) (74)
- Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage. (2005) (74)
- Enteropathogenic and enterohemorrhagic Escherichia coli infections: emerging themes in pathogenesis and prevention. (2002) (73)
- Bacterial invasion: Force feeding by Salmonella (1999) (73)
- A Comprehensive Proteomic Analysis of the Type III Secretome of Citrobacter rodentium* (2009) (73)
- Isolation and characterization of Salmonella typhimurium and Yersinia pseudotuberculosis-containing phagosomes from infected mouse macrophages: Y. pseudotuberculosis traffics to terminal lysosomes where they are degraded. (1998) (72)
- Modulation of Host Cytoskeleton Function by the Enteropathogenic Escherichia coli and Citrobacter rodentium Effector Protein EspG (2005) (71)
- Enteropathogenic Escherichia coli Infection Induces Expression of the Early Growth Response Factor by Activating Mitogen-Activated Protein Kinase Cascades in Epithelial Cells (2001) (70)
- Genomic O Island 122, Locus for Enterocyte Effacement, and the Evolution of Virulent Verocytotoxin-Producing Escherichia coli (2008) (70)
- Type III effector-mediated processes in Salmonella infection. (2012) (70)
- SseL Is a Salmonella-Specific Translocated Effector Integrated into the SsrB-Controlled Salmonella Pathogenicity Island 2 Type III Secretion System (2006) (69)
- Enteropathogenic Escherichia coli inhibits phagocytosis. (1999) (69)
- Impact of Salmonella Infection on Host Hormone Metabolism Revealed by Metabolomics (2011) (69)
- The medium-/long-chain fatty acyl-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase 1 starvation-stress response (SSR) locus. (1999) (69)
- Haemophilus influenzae lipopolysaccharide disrupts confluent monolayers of bovine brain endothelial cells via a serum-dependent cytotoxic pathway. (1992) (68)
- Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: Implications for a subunit vaccine (2006) (68)
- Delivery of dangerous goods: type III secretion in enteric pathogens. (2002) (67)
- Bacterial Stimulation of the TLR-MyD88 Pathway Modulates the Homeostatic Expression of Ileal Paneth Cell α-Defensins (2012) (67)
- Sequestosome-1/p62 Is the Key Intracellular Target of Innate Defense Regulator Peptide* (2009) (66)
- Characterization of two virulence proteins secreted by rabbit enteropathogenic Escherichia coli, EspA and EspB, whose maximal expression is sensitive to host body temperature (1997) (66)
- Salmonella Phage ST64B Encodes a Member of the SseK/NleB Effector Family (2011) (65)
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- Age-Matching in Pediatric Fecal Matter Transplants (2021) (0)
- Abstract 1778: Bacterial regulation of innate and adaptive tumor immunity in metastatic breast cancer (2021) (0)
- Let Them Eat Dirt : Raising Children With Their Microbes (2016) (0)
- Characterization of rOrf8/EscI of the enteropathogenic Escherichia coli as an inner rod protein (2012) (0)
- Results Salmonella Association with Polarized MDCK Cell Monolayers Requires Bacterial Protein Synthesis and Causes Loss of Host MicroviUi (2002) (0)
- 348 BACTERIAL EFFECTORS AND THE EVASION OF HOST DEFENSES IN SALMONELLA INFECTION. (2004) (0)
- BACTERIAL EFFECTORS AND THE EVASION OF HOST DEFENSES IN SALMONELLA INFECTION.: 348 (2004) (0)
- Crystal structure of EscU C-terminal domain with N262D mutation, Space group P 21 21 21 (2008) (0)
- Therapeutics : from Pathogenesis to Salmonella (2014) (0)
- Pathogenicity Islands Clusters of Virulence Factors (2000) (0)
- Host factor reveals the intrinsic enzymatic activity of a bacterial effector. (2008) (0)
- Crystal structure of the CesA-EspA complex (2004) (0)
- UNDERSTANDING MICROBIAL PATHOGENESIS AS A BASIS FOR VACCINE DESIGN (2003) (0)
- Immunomodulatory activity of synthetic innate defence regulators (IDRs) (134.45) (2009) (0)
- Role of the microbiota in asthma (2015) (0)
- Table of Contents (1996) (0)
- Development of Helicobacter pylori-infected human antral primary cell cultures (1998) (0)
- Bacterial Pathogen Translocation Across the Gastrointestinal Barrier (1997) (0)
- Immunity to bacterial infection (excluding mycobacteria) (WS-060) Chairpersons: Masao Mitsuyama, Seppo Meri (2010) (0)
- Comparison of the relative levels a of metabolites of the linoleic acid pathway in sera from BT and LL patients before and after antibiotic treatment. (2013) (0)
- Tubulobulbar Complexes Formed In Sertoli Cells In Primary Cultures Associate With Intercellular Junction Elements (2012) (0)
- LSC 2013 abstract - Perinatal antibiotic treatment affects murine microbiota, immune responses, and pathology in models of allergic asthma and hypersensitivity pneumonitis (2013) (0)
- The Role of the Microbiome in Early Childhood (2017) (0)
- Crystal structural of the mutated N262A EscU C-terminal domain (2008) (0)
- LIPOPOLYSACCHARIDE INDUCES APOPTOSIS IN BOVINE PULMONARY ENDOTHELIAL CELLS A ROLE FOR THE CERAMIDE PATHWAY (1996) (0)
- Vaccine enterohemorrhagic Escherichia coli (2002) (0)
- Type III secretion chaperone CesT (2001) (0)
- High-resolution cryo-EM structure of the EspA filament from EPEC: revealing the mechanism of effector translocation in the type 3 secretion system (2020) (0)
- Confronting the microbe menace (2000) (0)
- Intestinal microbiota balance modulates host susceptibility to infection with enteric pathogenss (2007) (0)
- Crystal structural of the mutated G247T EscU/SpaS C-terminal domain (2008) (0)
- Location of epitopes on f like pili (1986) (0)
- Pachymoside A — A Novel Glycolipid Isolated from the Marine Sponge Pachymatisma johnstonia. (2004) (0)
- disease generation of diarrhoea during infectious enteric Gap junction hemichannels contribute to the (0)
- Special Edition of Gut Microbes (2012) (0)
- Introduction to microbiota: agents for health and disease (2011) (0)
- Salmonella typhimurium interactions with the endocytic pathway in mammalian cells (1996) (0)
- Bacterial diarrheas caused by Escherichia coli and Salmonella species (1995) (0)
- 17 Flow cytometric analysis of Salmonella-containing vacuoles (2002) (0)
- Crystal structural of native EscU C-terminal domain (2008) (0)
- Infections: Feeding the microbial multitudes: co-infection in a malnourished host (2017) (0)
- Helicobacter pylori infection upregulates IQGAP-1 expression in primary cultures of human antral epithelial cells (2000) (0)
- ZirS C-terminal Domain (2012) (0)
- Type III Secretion Chaperone SigE (2001) (0)
- 448 CHARACTERIZATION OF SECRETED PROTEINS OF NON-O157:H7 ENTEROHEMORRHAGIC ESCHERICHIA COLI SEROTYPES AND THEIR USE IN BOVINE VACCINE STUDIES. (2006) (0)
- Early life gut microbial alterations in children diagnosed with asthma by three years of age (2015) (0)
- CRYSTAL STRUCTURE OF C-TERMINAL 282-RESIDUE FRAGMENT OF INTIMIN IN COMPLEX WITH TRANSLOCATED INTIMIN RECEPTOR (TIR) INTIMIN-BINDING DOMAIN (2000) (0)
- Crystal structure of the EscU C-terminal domain with P263A mutation,space group P 1 21 1 (2008) (0)
- The molecular basis of bacterial pathogenicity: an overview (2009) (0)
- A Diarrheal Pathogen , Enteropathogenic Escherichia coil ( EPEC ) , Triggers a Flux of Inositol Phosphates in Infected Epithelial Cells By Vida Foubister (2003) (0)
- Author response: Bacterial–fungal interactions in the neonatal gut influence asthma outcomes later in life (2021) (0)
- Regulator Peptide Intracellular Target of Innate Defense Sequestosome-1 / p 62 Is the Key Accelerated Publication : (2009) (0)
- The Canadian Bacterial Diseases Network: a collaboration of universities, industry and government. (1995) (0)
- the art of bacterialwarfare (2010) (0)
- the Murine Macrophage Line RAW 264 . 7 Functional Expression of Nramp 1 In Vitro in (1999) (0)
- Vaccine comprising the EspA-associated protein Escherichia coli pathogenic (1997) (0)
- Man versus pathogen: can we talk? Molecular cross-talk between epithelial cells and pathogenic microorganisms sponsored by the American Society for Cell Biology and the European Molecular Biology Organization, Arolla, Switzerland, August 18-23, 1991. (1991) (0)
- Built Environment, Microbiota and Asthma at Age 3: Longitudinal Follow-Up in a Canadian Birth Cohort (2018) (0)
- Erratum (2003) (0)
- Quorum Sensing Modulates Bacterial Virulence and Colonization Dynamics During an Enteric Infection (2023) (0)
- Repression of Salmonella phoP expression by small molecules from physiological bile 1 2 (2012) (0)
- Salmonella typhimurium interations with host cells (1998) (0)
- Studying microbial pathogenesis and bacterial diseases. Interview by Hannah Branch. (2013) (0)
- S30 Th17 cells mediate intestinal fibrosis in mice (2010) (0)
- GrlR, a negative regulator in enteropathogenic E. coli, also represses the expression of LEE virulence genes independently of its interaction with its cognate partner GrlA (2023) (0)
- CONCISE COMMUNICATION Penetration of Clinical Isolates of Pseudomonas aeruginosa through MDCK Epithelial Cell Monolayers (0)
- Table 2 Canadian association of Gastroenterology (CaG)-Canadian Institutes of Health Research (CIHR) Partner-Funded grants 2011 (2011) (0)
- CRYSTAL STRUCTURE OF C-TERMINAL 282-RESIDUE FRAGMENT OF ENTEROPATHOGENIC E. COLI INTIMIN (2000) (0)
- Metronidazole-induced perturbations of the intestinal microbiota increase host susceptibility to Citrobacter rodentium-induced colitis (2009) (0)
- Achtman a Preclinical Model of Severe Malaria Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in (2012) (0)
- CD8 T Cells Magnitude but Compromises the Function of Pathogen Proliferation Governs the (0)
- La menace microbienne des maladies infectieuses (2011) (0)
- Salmonella's deceiving signals. (1993) (0)
- Transfection of Sertoli cells ex vivo; Opening the door to the in vitro study of junction turnover in the seminiferous epithelium (2006) (0)
- S1721 T Cells Contribute to the Intestinal Fibrosis Induced By Chronic Salmonella Infection in Mice (2008) (0)
- Dynamic proteomic profiling of the Salmonella-host interplay reveals new modes of action for known and novel virulence factors (2019) (0)
- Intracellular Trafficking of Salmonella Typhimurium within HeLa Epithelial Cells (1993) (0)
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What Schools Are Affiliated With B. Brett Finlay?
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