Benoît De Crombrugghe

Benoît De Crombrugghe's AcademicInfluence.com Rankings

Biology

#7701

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#10660

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Developmental Biology

#90

World Rank

#96

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Molecular Biology

#911

World Rank

#934

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Biology

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Benoît De Crombrugghe's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. (2002) (1635)
Some recent advances in the chemistry and biology of transforming growth factor-beta (1987) (1233)
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene (1997) (1098)
Evidence for two functional gal promoters in intact Escherichia coli cells. (1981) (932)
A new long form of Sox5 (L‐Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene (1998) (809)
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. (2001) (592)
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization (2001) (558)
Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis (1997) (537)
Cyclic AMP receptor protein: role in transcription activation. (1984) (521)
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. (2005) (511)
Transcriptional mechanisms of chondrocyte differentiation. (2000) (480)
The family of collagen genes. (1990) (471)
Regulatory mechanisms in the pathways of cartilage and bone formation. (2001) (461)
Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice (2014) (425)
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. (2004) (424)
Transcriptional mechanisms in osteoblast differentiation and bone formation. (2003) (405)
Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest (2003) (405)
Role of the CCAAT-binding protein CBF/NF-Y in transcription. (1998) (365)
L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. (2001) (360)
Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. (2000) (359)
Genetic regulation of bone mass and susceptibility to osteoporosis. (2006) (327)
A Gene for a Novel Zinc-finger Protein Expressed in Differentiated Epithelial Cells and Transiently in Certain Mesenchymal Cells* (1996) (326)
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. (2006) (324)
Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. (1995) (290)
Chondrocyte-specific Enhancer Elements in the Col11a2Gene Resemble the Col2a1 Tissue-specific Enhancer* (1998) (282)
Transforming growth factor beta: biochemistry and roles in embryogenesis, tissue repair and remodeling, and carcinogenesis. (1988) (276)
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice (2010) (276)
Potent Inhibition of the Master Chondrogenic FactorSox9 Gene by Interleukin-1 and Tumor Necrosis Factor-α* (2000) (271)
Phosphorylation of SOX9 by Cyclic AMP-Dependent Protein Kinase A Enhances SOX9's Ability To Transactivate aCol2a1 Chondrocyte-Specific Enhancer (2000) (264)
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. (2004) (264)
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. (2004) (256)
SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification (2010) (254)
The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. (2001) (243)
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling (2006) (241)
Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice (1995) (226)
Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. (2010) (199)
Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts. (1977) (199)
Lac DNA, RNA polymerase and cyclic AMP receptor protein, cyclic AMP, lac repressor and inducer are the essential elements for controlled lac transcription. (1971) (195)
Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis. (2002) (191)
Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma. (2007) (188)
β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis (2012) (184)
Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors. (2003) (183)
Toward understanding SOX9 function in chondrocyte differentiation. (1998) (181)
Positive Regulation of Adult Bone Formation by Osteoblast‐Specific Transcription Factor Osterix (2009) (179)
Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts. (1985) (178)
Selective activation of transcription by a novel CCAAT binding factor. (1988) (177)
Three High Mobility Group-like Sequences within a 48-Base Pair Enhancer of the Col2a1 Gene Are Required for Cartilage-specific Expression in Vivo * (1998) (172)
Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs. (1991) (168)
Three classes of mutations in the A subunit of the CCAAT-binding factor CBF delineate functional domains involved in the three-step assembly of the CBF-DNA complex (1996) (164)
Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix (2008) (162)
Sox9‐expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons (2010) (161)
Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. (1994) (159)
Regulation of bone formation and remodeling by G-protein-coupled receptor 48 (2009) (157)
Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family. (2001) (154)
Determination of functional domains in the C subunit of the CCAAT-binding factor (CBF) necessary for formation of a CBF-DNA complex: CBF-B interacts simultaneously with both the CBF-A and CBF-C subunits to form a heterotrimeric CBF molecule (1996) (153)
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase (2009) (151)
Generation of aggrecan‐CreERT2 knockin mice for inducible Cre activity in adult cartilage (2009) (148)
Use of a New Rat Chondrosarcoma Cell line to Delineate a 119-Base Pair Chondrocyte-specific Enhancer Element and to Define Active Promoter Segments in the Mouse Pro-α1(II) Collagen Gene (*) (1995) (146)
The postnatal role of Sox9 in cartilage (2012) (144)
A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. (1995) (140)
Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor. (1992) (137)
Transcriptional activation encoded by the v-fos gene. (1986) (137)
A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding. (1988) (135)
The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferation. (2003) (135)
Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate. (1969) (132)
An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes (1996) (130)
Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. (1991) (129)
Effect of Rho on transcription of bacterial operons. (1973) (125)
Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice* (2003) (125)
Sp1 and Sp3 Transcription Factors Mediate Interleukin-1β Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes* (2003) (125)
Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain (1992) (123)
TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation (1993) (120)
Interferon alfa down‐regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice (2003) (116)
DNA Binding Specificity of the CCAAT-binding Factor CBF/NF-Y* (1997) (110)
Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene. (1987) (110)
Two different negative and one positive regulatory factors interact with a short promoter segment of the alpha 1 (I) collagen gene. (1990) (103)
Genetic evidence for the vital function of osterix in cementogenesis (2012) (102)
Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma. (2005) (102)
Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation. (2006) (101)
Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts. (1996) (101)
The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. (1990) (99)
Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters. (1979) (96)
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. (2014) (95)
Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes. (1993) (94)
Identification of SOX9 Interaction Sites in the Genome of Chondrocytes (2010) (94)
Chondrocytes Directly Transform into Bone Cells in Mandibular Condyle Growth (2015) (92)
Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure. (2010) (89)
Regulation of lac mRNA synthesis in a soluble cell-free system. (1971) (87)
SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters (2014) (86)
Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation (2008) (86)
Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth. (2004) (86)
Attenuation of fibrosis in vitro and in vivo with SPARC siRNA (2010) (82)
Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5 (2008) (81)
SOX9 exerts a bifunctional effect on type II collagen gene (COL2A1) expression in chondrocytes depending on the differentiation state. (2003) (80)
Effects of transformation on fibronectin gene expression using cloned fibronectin cDNA. (1981) (80)
rDlx, a novel distal-less-like homeoprotein is expressed in developing cartilages and discrete neuronal tissues. (1994) (79)
Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro (2013) (79)
Cloning and Characterization of a Transcription Factor That Binds to the Proximal Promoters of the Two Mouse Type I Collagen Genes* (1997) (79)
Transcriptional control of the mouse alpha 2(I) collagen gene: functional deletion analysis of the promoter and evidence for cell-specific expression (1986) (78)
Type I Collagen (2002) (78)
Studies on Transcription Activation by the Multimeric CCAAT-binding Factor CBF (*) (1995) (77)
Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene. (2000) (75)
Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts* (2011) (75)
Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance. (2010) (74)
Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor. (1990) (74)
The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern. (1993) (73)
A New Long Form of c-Maf Cooperates with Sox9 to Activate the Type II Collagen Gene* (2002) (72)
Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements. (2003) (71)
Interactions between PIAS Proteins and SOX9 Result in an Increase in the Cellular Concentrations of SOX9* (2006) (71)
Point mutations and small substitution mutations in three different upstream elements inhibit the activity of the mouse alpha 2(I) collagen promoter. (1988) (70)
Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice. (1993) (70)
Biochemical analysis of the B subunit of the heteromeric CCAAT-binding factor. A DNA-binding domain and a subunit interaction domain are specified by two separate segments. (1992) (69)
Use of recombinant plasmids to characterize collagen RNAs in normal and transformed chick embryo fibroblasts. (1979) (69)
Regulation of a collagen gene promoter by the product of viral mos oncogene (1985) (69)
Mutations in the Escherichia coli operon that define two promoters and the binding site of the cyclic AMP receptor protein. (1982) (67)
Isolation of genomic DNA clones spanning the entire fibronectin gene. (1983) (67)
Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen (1995) (66)
Transcriptional suppression of cellular gene expression by c-Myc (1991) (65)
The properties of thyroglobulin. XI. The reduction of the disulfide bonds. (1966) (63)
Minimal DNA sequences that control the cell lineage-specific expression of the pro alpha 2(I) collagen promoter in transgenic mice (1992) (63)
The transcription factor Sox9 is degraded by the ubiquitin-proteasome system and stabilized by a mutation in a ubiquitin-target site. (2005) (62)
Nucleotide sequence of the operator-promoter region of the galactose operon of Escherichia coli. (1977) (62)
Separate binding sites for nuclear factor 1 and a CCAAT DNA binding factor in the mouse alpha 2(I) collagen promoter. (1987) (61)
A uniquely conserved regulatory signal is found around the translation initiation site in three different collagen genes. (1983) (61)
A sequence conserved in both the chicken and mouse alpha 2(I) collagen promoter contains sites sensitive to S1 nuclease. (1984) (59)
Stimulation by cyclic AMP and ppGpp of chloramphenicol acetyl transferase synthesis. (1973) (58)
Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts. (1978) (58)
Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification. (2012) (58)
ATPase activity required for termination of transcription by the Escherichia coli protein factor rho. (1976) (57)
Sclerostin is a direct target of osteoblast-specific transcription factor osterix. (2010) (56)
FGF signaling antagonizes cytokine-mediated repression of Sox9 in SW1353 chondrosarcoma cells. (2003) (56)
Regulation or procollagen messenger ribonucleic acid levels in Rous sarcoma virus transformed chick embryo fibroblasts. (1981) (56)
Osterix Regulates Tooth Root Formation in a Site-specific Manner (2015) (55)
Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. (2007) (54)
Coordinate patterns of expression of type I and III collagens during mouse development. (1995) (54)
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice. (2003) (52)
Identification and Characterization of MicroRNAs Controlled by the Osteoblast-Specific Transcription Factor Osterix (2013) (51)
Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter. (2008) (51)
A conserved nucleotide sequence, coding for a segment of the C-propeptide, is found at the same location in different collagen genes. (1983) (49)
Activation of a fibroblast-specific enhancer of the proalpha2(I) collagen gene in tight-skin mice. (2001) (47)
Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human α2(I) Collagen (COL1A2) Gene* (2001) (47)
Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice. (1986) (45)
DNA sequence comparison of the regulatory signals at the 5' end of the mouse and chick alpha 2 type I collagen genes. (1984) (44)
Regulation of the expression of genes encoding types I, II, and III collagen during chick embryonic development. (1983) (44)
Structure of the promoter for chicken alpha 2 type I collagen gene. (1981) (43)
Thyroglobulin from human goiters. Effects of iodination on sedimentation and iodoamino acid synthesis. (1967) (42)
Enhanced type III collagen gene expression during bleomycin induced lung fibrosis. (1993) (40)
Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli. (1970) (39)
Isolation and characterization of overlapping genomic clones covering the chicken alpha 2 (type I) collagen gene. (1980) (38)
CBF/NF-Y functions both in nucleosomal disruption and transcription activation of the chromatin-assembled topoisomerase IIalpha promoter. Transcription activation by CBF/NF-Y in chromatin is dependent on the promoter structure. (2001) (38)
Construction of a recombinant bacterial plasmid containing pro-alpha 1(I) collagen DNA sequences. (1980) (38)
E6-AP/UBE3A Protein Acts as a Ubiquitin Ligase toward SOX9 Protein* (2013) (37)
Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1). (1995) (37)
Activation of Proalpha2(I) collagen promoter during hepatic fibrogenesis in transgenic mice. (1998) (36)
Differential binding of a CCAAT DNA binding factor to the promoters of the mouse alpha 2(I) and alpha 1(III) collagen genes. (1986) (35)
Construction of a recombinant bacterial plasmid containing a chick pro-alpha2 collagen gene sequence. (1978) (35)
Twisted Gastrulation Modulates Bone Morphogenetic Protein-induced Collagen II and X Expression in Chondrocytes in Vitro and in Vivo* (2006) (34)
The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template (2010) (34)
A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo. (2004) (34)
Downregulation of rheumatoid arthritis‐related antigen RA‐A47 (HSP47/colligin‐2) in chondrocytic cell lines induces apoptosis and cell‐surface expression of RA‐A47 in association with CD9 (2005) (33)
Molecular cloning and characterization of a novel rat activin receptor. (1992) (32)
Molecuar model of the DNA interaction site for the cyclic AMP receptor protein. (1981) (32)
Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors. (2010) (32)
The properties of thyroglobulin. 13. The structure of reduced alkylated thyroglobulin. (1966) (31)
Transcriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: A negative role for NF‐κB (2000) (30)
A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6* (2016) (29)
Identification of the promoter and first exon of the mouse alpha 1 (III) collagen gene. (1985) (29)
A fibroblast-specific factor binds to an upstream negative control element in the promoter of the mouse alpha 1(I) collagen gene. (1991) (29)
On the mechanism of action of lac repressor. (1971) (28)
Evidence for three major transcription activation elements in the proximal mouse proalpha2(I) collagen promoter. (1996) (28)
Transcription in vitro of bacteriophage lambda 4S RNA: studies on termination and rho protein. (1977) (27)
Osteoblast‐Specific Expression of the α2(I) Collagen Promoter in Transgenic Mice: Correlation with the Distribution of TGF‐β1 (1993) (27)
BAC constructs in transgenic reporter mouse lines control efficient and specific LacZ expression in hypertrophic chondrocytes under the complete Col10a1 promoter (2006) (27)
Specificity Protein 7 Is Required for Proliferation and Differentiation of Ameloblasts and Odontoblasts (2018) (27)
Release of polarity in Escherichia coli by gene N of phage lambda: termination and antitermination of transcription. (1974) (26)
The exon/intron structure of the 3'-region of the pro alpha 2(I) collagen gene. (1981) (26)
Structure and function of the promoter-enhancer region of polyoma and SV40. (1983) (25)
Decrease in the levels of nuclear RNA precursors for alpha 2 collagen in Rous sarcoma virus transformed fibroblasts. (1981) (24)
Transforming growth factor‐β isoforms differently stimulate proα2 (I) collagen gene expression during wound healing process in transgenic mice (2002) (24)
Transcriptional control mechanisms for the expression of type I collagen genes. (1991) (23)
DNase I sensitivity of the alpha 2(I) collagen gene: correlation with its expression but not with its methylation pattern. (1984) (23)
Sp7 and Runx2 molecular complex synergistically regulate expression of target genes (2014) (22)
The 5'-terminal nucleotide sequence of galactose messenger ribonucleic acid of Escherichia coli. (1974) (21)
Characterization of two distinct positive cis-acting elements in the mouse alpha 1 (III) collagen promoter. (1989) (21)
Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation. (2007) (21)
Isolation and characterization of a genomic clone encoding chick alpha 1 type III collagen. (1983) (20)
Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation (2015) (20)
SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc (2015) (20)
The Osterix Transcription Factor Down-Regulates Interleukin-1α Expression in Mouse Osteosarcoma Cells (2008) (19)
Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene. (1993) (19)
Purification, characterization, and role of CCAAT-binding factor in transcription. (1996) (18)
Determination of the nucleotide sequence of part of the regulatory region for the galactose operon from Escherichia coli. (1977) (18)
Unusual methylation pattern of the alpha 2 (l) collagen gene. (1982) (18)
Interactions of RNA polymerase and the cyclic AMP receptor protein on DNA of the E. coli galactose operon. (1983) (18)
Attenuation of Expression of Extracellular Matrix Genes with siRNAs to SPARC and CTGF in Skin Fibroblasts of CTGF Transgenic Mice (2011) (18)
cDNA library screening using the SOS recruitment system. (2001) (17)
The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene. (1994) (17)
Tissue-specific expression of the mouse alpha 2(I) collagen promoter. Studies in transgenic mice and in tissue culture cells. (1992) (17)
Purification and functional characterization of a DNA-binding protein that interacts with a negative element in the mouse alpha 1(I) collagen promoter. (1991) (17)
Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx. (2012) (17)
The mouse type-III procollagen-encoding gene: genomic cloning and complete DNA sequence. (1994) (17)
Conservation of binding sites for regulatory factors in the coordinately expressed alpha 1 (I) and alpha 2 (I) collagen promoters. (1991) (16)
Structural Insights into Histone Demethylase NO66 in Interaction with Osteoblast-specific Transcription Factor Osterix and Gene Repression* (2013) (15)
Deletion analysis of the mouse alpha 1(III) collagen promoter. (1988) (15)
Control of type I collagen genes in scleroderma and normal fibroblasts. (1990) (15)
Purification of BBF, a DNA-binding protein recognizing a positive cis-acting element in the mouse alpha 1(III) collagen promoter. (1992) (14)
Promoter sequences of murine alpha A crystallin, murine alpha 2(I) collagen or of avian sarcoma virus genes linked to the bacterial chloramphenicol acetyl transferase gene direct tissue-specific patterns of chloramphenicol acetyl transferase expression in transgenic mice. (1985) (14)
Transforming growth factor-beta isoforms differently stimulate proalpha2 (I) collagen gene expression during wound healing process in transgenic mice. (2002) (14)
Restriction enzyme digestions identify discrete domains in the chromatin around the promoter of the mouse alpha 2(I) collagen gene. (1986) (12)
Partial purification and characterization of the messenger RNA for cell fibronectin. (1979) (12)
Accurate in vitro transcriptional initiation of the chick alpha 2 (Type I) collagen gene. (1981) (12)
A repetitive structure in the chick alpha 2-collagen gene. (1981) (11)
Osterix is required for cranial neural crest-derived craniofacial bone formation. (2013) (11)
Bacteriophage lambda hin function. II. Enhanced stability of lambda messenger RNA. (1980) (11)
Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. (1996) (11)
Primary structure of the carbohydrate‐containing regions of the carboxyl propeptides of type I procollagen (1981) (10)
The properties of thyroglobulin. XIV. The structure of reoxidized thyroglobulin. (1966) (10)
Formation of a type I collagen RNA dimer by intermolecular base-pairing of a conserved sequence around the translation initiation site. (1987) (9)
Transcription of the chicken alpha 2 (Type I) collagen gene by homologous cell-free extracts. (1982) (9)
Studies on the structure of the mouse CBF-A gene and properties of a truncated CBF-A isoform generated from an alternatively spliced RNA. (1994) (8)
Expression Pattern and Gene Characterization ofAsporin (2001) (8)
Persistent Low Level of Osterix Accelerates Interleukin-6 Production and Impairs Regeneration after Tissue Injury (2013) (8)
Characterization of Mesenchymal-Fibroblast Cells Using the Col1a2 Promoter/Enhancer. (2017) (7)
Osteoblast-specific expression of the alpha 2(I) collagen promoter in transgenic mice: correlation with the distribution of TGF-beta 1. (1993) (6)
Nucleotide sequence of a cDNA coding for the amino-terminal region of human prepro alpha 1(III) collagen. (1988) (6)
Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells (2021) (6)
Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes (2012) (5)
Control of expression of genetic information in E. coli by cyclic AMP. (1972) (5)
Termination and antitermination in transcription: control of gene expression. (1974) (5)
Aging and cancer: cyclic 3', 5'-adenosine monophosphate and altered gene activity. (1982) (4)
Transgenic mice with deficiencies in cartilage collagens: possible models for gene therapy. (1995) (4)
Joint formation requires muscle formation and contraction. (2009) (4)
CBF/NF-Y Functions Both in Nucleosomal Disruption and Transcription Activation of the Chromatin-assembled Topoisomerase IIα Promoter (2001) (4)
Chicken embryo extracts contain a factor that preferentially blocks the accumulation of RNA polymerase II transcripts in a cell-free system. (1982) (4)
Parathyroid hormone and prostaglandin E2 preferentially increase luciferase levels in bone of mice harboring a luciferase transgene controlled by elements of the pro-alpha1(I) collagen promoter. (2000) (3)
Purification of a novel factor which binds to the mouse α2 (I) collagen promoter (1993) (3)
Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters (2015) (3)
Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs. (1992) (2)
Cell-specific in vivo DNA-protein interactions at the proximal promoters of the pro alpha 1(I) and the pro alpha2(I) collagen genes. (1997) (2)
Structure and expression of collagen genes. (1987) (2)
Structural and functional studies on the interstitial collagen genes. (1985) (1)
Structural and functional analysis of the genes for alpha 2(I) and alpha 1(III) collagens. (1985) (1)
Purification of a novel factor which binds to the mouse alpha 2 (I) collagen promoter. (1993) (1)
Systems for generating and detecting mutations in the galactose operon promoter region. (1982) (1)
V-fos stimulates expression of the alpha 1(III) collagen gene in NIH 3T3 cells. (1986) (1)
Isolation and characterization of genomic DNA coding for alpha 2 type I collagen. (1980) (0)
Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice (2023) (0)
Structural differences in normally and poorly iodinated thyroglobulin. (1969) (0)
[Quantitative aspects of the iodine cycle in normal subjects living in Belgium]. (1963) (0)
Osteoblasts clock in for their day job. (2005) (0)
Regulation of gene expression by cyclic AMP in Escherichia coli. (1973) (0)
Human thyroglobulin: iodination and sedimentation rate. (1967) (0)
Expression of porcine transforming growth factor-beta. (1995) (0)
List of Contributors (2020) (0)
[Modification of thyroglobulin structure by iodation in vitro]. (1969) (0)
[Blood volume and adaptation of the heart in anemia in the rabbit]. (1963) (0)
Phosphorylation of SOX9 by Cyclic AMP-Dependent Protein Kinase A Enhances SOX9's Ability To Transactivate aCol2a1 Chondrocyte-Specific Enhancer (2000) (0)
[Investigations on the goitertogenesis mechanism during adolescence]. (1966) (0)
[Measurement of cardiac output in the rabbit by radiocardiography]. (1960) (0)
[Iodine deficiency and metabolism of thyroxine in rats]. (1965) (0)

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Published Works

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