Billie Kenneth Koe
#161,048
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Billie Kenneth Koemedical Degrees
Medical
#3239
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#3697
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Pharmacology
#393
World Rank
#445
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Medical
Billie Kenneth Koe's Degrees
- Bachelors Pharmacy University of California, San Francisco
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(Suggest an Edit or Addition)Billie Kenneth Koe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- p-Chlorophenylalanine: a specific depletor of brain serotonin. (1966) (1767)
- Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. (1976) (505)
- Antiamphetamine effects following inhibition of tyrosine hydroxylase. (1966) (455)
- 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. (1990) (335)
- Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin. (1983) (229)
- Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins. (1984) (159)
- Separation of alpha 1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds. (1991) (135)
- Behavioral effects of L-α-methyltyrosine, an inhibitor of tyrosine hydroxylase (1965) (134)
- The pharmacology of para-chlorophenylalanine, a selective depletor of serotonin stores. (1968) (106)
- Clinical‐pharmacological evaluation of p‐chlorophenylalanine: A new serotonin‐depleting agent (1966) (72)
- Preclinical pharmacology of sertraline: a potent and specific inhibitor of serotonin reuptake. (1990) (65)
- Structure-activity relationship of quinazolinedione inhibitors of calcium-independent phosphodiesterase. (1991) (63)
- Pharmacology of sertraline: a review. (1988) (62)
- Treatment with sertraline, a new serotonin uptake inhibitor, reduces voluntary ethanol consumption in rats. (1988) (58)
- A novel class of "GABAergic" agents: 1-aryl-3-(aminoalkylidene)oxindoles. (1989) (56)
- 3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one: A Potent and Selective Serotonin (5-HT1B) Agonist and Rotationally Restricted Phenolic Analogue of 5-Methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole. (1991) (56)
- Neuroleptic activity in 5-aryltetrahydro-gamma-carbolines. (1980) (45)
- Enhancement of brain [3H]flunitrazepam binding and analgesic activity of synthetic cannabimimetics. (1985) (42)
- Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2-imidazolidinones. (1991) (41)
- Sertraline, a selective inhibitor of serotonin uptake, induces subsensitivity of beta-adrenoceptor system of rat brain. (1987) (36)
- m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism. (1967) (34)
- An instance of the occurrence of carcinogenic substances in certain barnacles. (1951) (27)
- 5-[(3-nitropyrid-2-yl)amino]indoles: novel serotonin agonists with selectivity for the 5-HT1D receptor. Variation of the C3 substituent on the indole template leads to increased 5-HT1D receptor selectivity. (1994) (27)
- Stepwise Dehydrogenation of the Colorless Polyenes Phytoene and Phytofluene with N-Bromosuccinimide to Carotenoid Pigments (1954) (26)
- Differential effects of the enantiomers of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) at dopamine receptor sites. (1983) (26)
- Sertraline potently displaces (+)-[3H]3-PPP binding to sigma sites in rat brain. (1989) (25)
- 1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano[3,2-e]indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors. (1992) (24)
- The isolation of carcinogenic and other polycyclic aromatic hydrocarbons from barnacles. (1952) (24)
- 4‐Amino(1,2,4)triazolo(4,3‐a)quinoxalines. A Novel Class of Potent Adenosine Receptor Antagonists and Potential Rapid‐Onset Antidepressants. (1991) (24)
- [3H]Ro 15-1788 binding to benzodiazepine receptors in mouse brain in vivo: marked enhancement by GABA agonists and other CNS drugs. (1987) (23)
- Stereospecific and potent analgetic activity for nantradol--a structurally novel, cannabinoid-related analgetic. (1979) (23)
- Inhibiting action of n-butyraldoxime on ethanol metabolism and on natural ethanol preference of C57BL mice. (1970) (21)
- Preparation and spectral characteristics of all trans- and a cis-phytofluene. (1953) (21)
- Blockade of heart 3H-norepinephrine up-take by 4-phenyl-1-aminotetralines: implications for the active conformation of imipramine-like drugs. (1974) (20)
- (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine binding to σ receptors in mouse brain in vivo (1989) (20)
- Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin. (1992) (19)
- GABA‐like Actions of Levonantradol (1981) (18)
- In vitro conversion of phytofluene and phytoene into carotenoid pigments. (1952) (18)
- Neuroleptic activity of the 5-aryltetrahydro-gamma-carboline series. Conformational requirements for interaction with central dopamine receptors. (1980) (17)
- Contrasting effects of ethyl beta-carboline-3-carboxylate (beta CCE) and diazepam on cerebellar cyclic GMP content and antagonism of both effects by Ro 15-1788, a specific benzodiazepine receptor blocker. (1983) (17)
- PA 132, a new antibiotic. I. Isolation and chemical properties. (1956) (16)
- Dependence of m-fluorophenylalanine toxicity on phenylalanine hydroxylase activity. (1967) (14)
- Facilitation of Benzodiazepine Binding by Levonantradol (1981) (13)
- Calcium-Independent Phosphodiesterase Inhibitors as Putative Antidepressants: (3-(Bicycloalkoxy)-4-methoxyphenyl)-2- imidazolidinones. (1991) (13)
- Neuroleptics from the 4a,9b-cis- and 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 2. (1986) (13)
- The isolation of carcinogenic and other polycyclic aromatic hydrocarbons from barnacles. II. The goose barnacle (Mitella polymerus). (1952) (13)
- ONE WAY CROSS TOLERANCE FROM MORPHINE TO NANTRADOL - A POTENT, NON-OPIOID ANALGETIC (1980) (13)
- Enhancement of benzodiazepine binding by methaqualone and related quinazolinones (1986) (13)
- Neuroleptic activity of chiral trans-hexahydro-gamma-carbolines. (1986) (12)
- Convulsions and elevation of tissue citric acid levels induced by 5-fluorotryptophan. (1966) (12)
- Chapter 5. Adaptive Changes in Central Nervous System Receptor Systems (1984) (11)
- Blockade of hepatic aldehyde dehydrogenase in mice on chronic ingestion of 4-bromopyrazole and 4-iodopyrazole. (1975) (11)
- Enhancement of benzodiazepine binding by progabide (SL 76002) and SL 75102 (1983) (10)
- Nicotinamide ethers: novel inhibitors of calcium-independent phosphodiesterase and [3H]rolipram binding. (1991) (10)
- Stereoisomerization of the polycis compounds, pro-γ-carotene and prolycopene in chickens and hens. (1951) (9)
- [3H] sertraline binding to rat brain membranes (2005) (8)
- Synthesis and dopamine autoreceptor activity of a 5-(methylmercapto)methyl-substituted derivative of (+/-)-3-PPP (3-(3-hydroxyphenyl)-1-n-propylpiperidine). (1985) (8)
- Behavioral effects of L-alpha-methyltyrosine, an inhibitor of tyrosine hydroxylase. (1965) (8)
- ISOLATION AND CHARACTERIZATION OF URINARY METABOLITES OF BENZQUINAMIDE AND BENZQUINAMIDE ALCOHOL. (1964) (8)
- CP-93,129: A Potent and Selective Agonist for the Serotonin (5-HT1B) Receptor and Rotationally Restricted Analog of RU-24,969 (1991) (7)
- A common mechanism of action for antidepressant drugs (1983) (7)
- BIOCHEMICAL ASSESSMENT OF THE NEUROLEPTIC ACTIVITY OF MOLINDONE (1979) (7)
- Chapter 22. Drugs and Deterrence of Alcohol Consumption (1969) (6)
- Inhibition of rat brain tryptophan hydroxylation with p-chloroamphetamine. (1976) (6)
- Structure‐Activity Relationship of Quinazolinedione Inhibitors of Calcium‐Independent Phosphodiesterase. (1991) (6)
- Inhibiting Action of p-Chlorophenylalanine and α-Methyl-p-chlorophenylalanine on Liver Phenylalanine and Tryptophan Hydroxylase (1967) (6)
- Levonantradol, a potent cannabinoid-related analgesic, antagonizes haloperidol-induced activation of striatal dopamine synthesis. (1981) (6)
- 4a,9b-trans-8-Fluoro-5-(4-fluorophenyl)-2-[4-(4-fluorophenyl)-4-hydroxybutyl]-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole hydrochloride, a new potent neuroleptic. (1980) (6)
- Synthesis of 5‐(2,3‐ditritiopropoxy)‐3‐(1,2,5,6‐tetrahydropyrid‐4‐yl)indole ([3H]CP‐96,501): A selective ligand for the serotonin (5‐HT1B) receptor (1991) (5)
- PREPARATION AND ANTIBIOTIC PROPERTIES OF SOME PHOSPHINYLAMINOPENICILLANIC ACIDS AND PHOSPHINOTHIOYLAMINOPENICILLANIC ACIDS. (1963) (5)
- Pa 150, PA 153, and PA 166: new polyene antifungal antibiotics. (1957) (5)
- Tryptophan hydroxylase inhibitors. (1971) (5)
- LOWER 2'-ALKYLTHIO ANALOGS AND DERIVATIVES OF GRISEOFULVIN VIA A MERCAPTANOLYSIS REACTION. (1964) (4)
- 5-cyano-1-[3-(N-methylpyrrolidin-2R-ylmethyl)indol-5-yl] benzimidazole (CP-161,242): A potent, centrally active 5-HT1D receptor agonist and benzodiazepine partial agonist (1995) (4)
- NONTRICYCLIC ANTIDEPRESSANT AGENTS DERIVED FROM CIS- AND TRANS-1-AMINO-4-ARYLTETRALINS (1985) (3)
- Some fluorescent substances contained in the marine "blood worm" (Thoracophelia mucronata). (1952) (3)
- NEUROLEPTIC ACTIVITY IN 5-ARYLTETRAHYDRO-Γ-CARBOLINES (1980) (3)
- Monoamine oxidase inhibitors antagonize the acceleration of brain dopamine synthesis induced by neuroleptic drugs in vivo: Implications for the treatment of tardive dyskinesia (1975) (3)
- Blockade of ethanol metabolism and reduced alcohol selection in c57bl mice by butyraldoxime. Abstr. (1969) (2)
- Oxindole N-Methyl-D-Aspartate (NMDA) antagonists (1993) (2)
- The nature of some fluorescing substances contained in a deep-sea mud. (1950) (2)
- Effects of serotoninergic agents on downregulation of beta-adrenoceptors by the selective serotonin reuptake inhibitor sertraline. (1995) (2)
- Blocking H 3 -Norepinephrine uptake and some guanethidine-induced effects with tricyclic psychotherapeutic drugs. (1972) (2)
- Dopamine receptor blockade by imidoline and its proposed active conformation. (1980) (1)
- D 1 and d 2 dopamine receptor antagonist character of selected neuroleptics (1985) (1)
- Clinical and biochemical effects of fenclonine: a serotonin depletor. (1968) (1)
- Contrasting locomotor effects of catecholamine releasers and tyrosine hydroxylase inhibitors in MAO-inhibited mice (1967) (1)
- Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 3. Carboxamidoalkyl derivatives. (1986) (1)
- Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives as therapeutic agent of psychosis (1994) (0)
- 5‐Cyano‐1‐(3‐(N‐methylpyrrolidin‐2R‐ylmethyl)indol‐5‐yl)benzimidazole ( CP‐161,242): A Potent, Centrally Active 5‐HT1D Receptor Agonist and Benzodiazepine Partial Agonist. (1996) (0)
- The Isolation and Study of Some Naturally Occurring Fluorescent Organic Compounds and Stereoisomerization of Prolycopene, Pro-γ-Carotene, and Lycopene in Chickens and Hens (1952) (0)
- Stereoisomerization of the polycis compounds, pro-gamma-carotene and prolycopene in chickens and hens. (1951) (0)
- Analogifremgangsmaade for the preparation of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalene-amine derivatives in racemic form or as optically active (1S) -enantiomers or pharmaceutically acceptable acid addition salts thereof (1980) (0)
- Neuroleptics from the 4a,9b-cis- and 4a,9b-trans-2,3,4,4a,5,9b-Hexahydro-1H-pyrido(4,3-b)indole Series. Part 2. (1987) (0)
- (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine binding to sigma receptors in mouse brain in vivo. (1989) (0)
- Nicotinamide Ethers: Novel Inhibitors of Calcium-Independent Phosphodiesterase and (3H)Rolipram Binding. (1991) (0)
- Analogifremgangsmaate for preparing therapeutically active 4-phenyl-1,2,3,4-tetrahydro-1-naftalenaminderivater (1980) (0)
- Neuroleptic Activity of Chiral trans‐Hexahydro‐γ‐carbolines. (2002) (0)
- Process for the preparation of trans-4-phenyl-1,2,-3,4-tetrahydro-1-naphthalen amine derivatives (1980) (0)
- Saccharin preference of butyraldoxime-treated C57BL mice (1972) (0)
- A process for preparing trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives or pharmaceutically acceptable acid addition salts thereof (1980) (0)
- Antagonism of 5-hydroxytryptamine by benzquinamide (1966) (0)
- SYNTHESIS AND DOPAMINE AUTORECEPTOR ACTIVITY OF A 5-(METHYLMERCAPTO)METHYL-SUBSTITUTED DERIVATIVE OF(.+-.)-3-PPP (3-(3-HYDROXYPHENYL)-1-PROPYLPIPERIDINE) (1985) (0)
- A process for preparing cis-4-phenyl1,2,3,4-tetrahydro-1-naphthalenamine derivatives or acid addition salts thereof (1980) (0)
- 4A,9B-TRANS-8-FLUORO-5-(4-FLUOROPHENYL)-2-(4-(4-FLUOROPHENYL)-4-HYDROXYBUTYL)-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO(4,3-B)INDOLE HYDROCHLORIDE, A NEW POTENT NEUROLEPTIC (1981) (0)
- Antidepressiva of the derivative of trans-4-phenyl-1,2,3,4-tetrahydro-1-Naphthalenamine (1980) (0)
- BIOCHEMICAL AND BEHAVIORAL EFFECTS OF DESMETHYLSERTRALINE (1992) (0)
- 6-Aminopenicillanamide and Methyl 6-Aminopenicillanate (1962) (0)
- The progress analogy for the preparation of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives thereof or pharmaceutically acceptablesyreadditionssalte (1980) (0)
- Additions and Corrections - Neuroleptic Activity of Chiral trans-Hexahrdro-γ-carbolines. (1986) (0)
- A Novel Class of “GABAergic” Agents: 1-Aryl-3-(aminoalkylidene)oxindoles. (1989) (0)
- Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-Hexahydro-1H-pyrido-(4,3-b)indole Series. Part 3. Carboxamidoalkyl Derivatives. (1987) (0)
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