Bill Robert Brinkley
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Cell Biology
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Molecular Biology
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Biology
Bill Robert Brinkley's Degrees
- PhD Cell Biology Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Bill Robert Brinkley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation (1997) (1872)
- Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation (1998) (1322)
- Microtubule organizing centers. (1985) (476)
- Control of microtubule assembly-disassembly by calcium-dependent regulator protein. (1978) (449)
- Managing the centrosome numbers game: from chaos to stability in cancer cell division. (2001) (417)
- CENP‐E, a novel human centromere‐associated protein required for progression from metaphase to anaphase. (1991) (388)
- Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. (1998) (322)
- Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells (1995) (320)
- Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. (2001) (317)
- Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients (1981) (304)
- PROCEDURE FOR EMBEDDING IN SITU SELECTED CELLS CULTURED IN VITRO (1967) (294)
- The centromere-kinetochore complex: a repeat subunit model (1991) (285)
- Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence. (1975) (277)
- Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence. (1984) (275)
- COLD‐LABILE AND COLD‐STABLE MICROTUBULES IN THE MITOTIC SPINDLE OF MAMMALIAN CELLS * (1975) (233)
- Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. (1978) (232)
- Immunofluorescence of mitotic spindles by using monospecific antibody against bovine brain tubulin. (1975) (225)
- The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro. (1967) (207)
- Ultrastructure and Interaction of the Kinetochore and Centriole in Mitosis and Meiosis (1970) (182)
- Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus (1979) (181)
- ULTRASTRUCTURAL ANALYSIS OF MITOTIC SPINDLE ELONGATION IN MAMMALIAN CELLS IN VITRO (1971) (179)
- Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. (1993) (177)
- Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. (1980) (168)
- Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin (1975) (167)
- Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected. (1998) (164)
- Tubulin assembly sites and the organization of cytoplasmic microtubules in cultured mammalian cells (1981) (158)
- The fine structure of the kinetochore of a mammalian cell in vitro (2004) (156)
- An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. (2007) (156)
- The cenpB gene is not essential in mice (1998) (145)
- Regulation of intracellular levels of calmodulin and tubulin in normal and transformed cells. (1981) (142)
- Movement and segregation of kinetochores experimentally detached from mammalian chromosomes (1988) (141)
- CILIA FORMATION IN CHINESE HAMSTER FIBROBLASTS IN VITRO AS A RESPONSE TO COLCEMID TREATMENT (1966) (139)
- Regulation of microfilaments and microtubules by calcium and cyclic AMP. (1979) (134)
- THE NUCLEOLI IN MITOTIC DIVISIONS OF MAMMALIAN CELLS IN VITRO (1965) (128)
- Microtubules in cultured cells; indirect immunofluorescent staining with tubulin antibody. (1980) (127)
- New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. (1999) (127)
- Arrangement of centromeres in mouse cells (2004) (126)
- Rotenone inhibition of spindle microtubule assembly in mammalian cells. (1974) (120)
- Chromosome condensation factor Brn1p is required for chromatid separation in mitosis. (2000) (115)
- Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells. (1994) (104)
- ARCHITECTURE AND FUNCTION OF THE MAMMALIAN CENTRIOLE (1967) (103)
- Centrophilin: a novel mitotic spindle protein involved in microtubule nucleation (1991) (100)
- Taxol-requiring mutant of Chinese hamster ovary cells with impaired mitotic spindle assembly (1983) (97)
- Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. (2003) (96)
- Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis (1998) (93)
- Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes [published erratum appears in J Cell Biol 1990 Dec;111(6 Pt 1):following 2800] (1990) (92)
- NudC Is Required for Plk1 Targeting to the Kinetochore and Chromosome Congression (2006) (90)
- Cytoplasmic microtubules in polymorphonuclear leukocytes: Effects of chemotactic stimulation and colchicine (1982) (88)
- Fractionation and initial characterization of the kinetochore from mammalian metaphase chromosomes (1985) (87)
- Ran-binding Protein-1 Is an Essential Component of the Ran/RCC1 Molecular Switch System in Budding Yeast (*) (1995) (86)
- THE FINE STRUCTURE OF THE NUCLEOLUS IN MITOTIC DIVISIONS OF CHINESE HAMSTER CELLS IN VITRO (1965) (83)
- Anti-kinetochore antibodies: use as probes for inactive centromeres. (1985) (82)
- Structure and control of assembly of cytoplasmic microtubules in normal and transformed cells. (1976) (82)
- Nuclear-mitotic apparatus protein: a structural protein interface between the nucleoskeleton and RNA splicing. (1994) (80)
- Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia. (1989) (78)
- Protein Phosphatase 4 Is Involved in Tumor Necrosis Factor-α-induced Activation of c-Jun N-terminal Kinase* (2002) (78)
- Aurora-C kinase supports mitotic progression in the absence of Aurora-B (2009) (78)
- Organization of centromeres in the decondensed nuclei of mature human sperm (1993) (76)
- Microtubules and beta cell function: effect of colchicine on microtubules and insulin secretion in vitro by mouse beta cells (1982) (76)
- Calmodulin-microtubule association in cultured mammalian cells (1984) (75)
- Microtubule initiation at kinetochores and centrosomes in lysed mitotic cells. Inhibition of site-specific nucleation by tubulin antibody (1979) (74)
- Chemical probes and possible targets for the induction of aneuploidy. (1985) (72)
- The kinetochore of mammalian chromosomes: structure and function in normal mitosis and aneuploidy. (1985) (72)
- Electron microscopy of spermatocytes previously studied in life: methods and some observations on micromanipulated chromosomes. (1979) (71)
- Nuclear matrix proteins as structural and functional components of the mitotic apparatus. (1995) (69)
- Tubulin interaction with kinetochore proteins: analysis by in vitro assembly and chemical cross-linking (1987) (68)
- The centrosome-associated Aurora/Ipl-like kinase family. (2000) (66)
- Ultrastructure of mammalian spermiogenesis. 3. The organization and morphogenesis of the manchette during rodent spermiogenesis. (1972) (65)
- Structure and molecular organization of the centromere-kinetochore complex. (1992) (64)
- Summary: Organization of the Cytoplasm (1982) (62)
- Tubulin nucleation and assembly in mitotic cells: evidence for nucleic acids in kinetochores and centrosomes. (1980) (60)
- Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells (2008) (59)
- Recurrent infection in glycogenosis type Ib: abnormal neutrophil motility related to impaired redistribution of adhesion sites. (1981) (59)
- Role of polyamines in cytokinesis of mammalian cells. (1979) (58)
- Impaired Motility of Neonatal PMN Leukocytes: Relationship to Abnormalities of Cell Orientation and Assembly of Microtubules in Chemotactic Gradients (1984) (57)
- Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells. (1996) (57)
- Mitosis : molecules and mechanisms (1989) (57)
- NITROUS OXIDE: EFFECTS ON THE MITOTIC APPARATUS AND CHROMOSOME MOVEMENT IN HELA CELLS (1973) (56)
- CENP-G: a new centromeric protein that is associated with the α-1 satellite DNA subfamily (1998) (55)
- Mitosis in cells with unreplicated genomes (MUGs): spindle assembly and behavior of centromere fragments. (1997) (53)
- Compound kinetochores of the Indian muntjac (1984) (52)
- Cell cycle-dependent expression and nucleolar localization of hCAP-H. (2001) (50)
- Tubulin assembly sites and the organization of microtubule arrays in mammalian cells. (1982) (50)
- Arrangements of kinetochores in mouse cells during meiosis and spermiogenesis (2004) (48)
- Microtubules and actin-containing filaments of normal, preneoplastic, and neoplastic mouse mammary epithelial cells. (1979) (48)
- The golgi apparatus during mitosis in human melanoma cells in vitro. (1970) (47)
- Dynamics of human replication protein A subunit distribution and partitioning in the cell cycle. (1996) (46)
- The identification of calmodulin-binding sites on mitochondria in cultured 3T3 cells (1981) (45)
- Aurora-C and Aurora-B share phosphorylation and regulation of cenp-A and borealin during mitosis (2008) (43)
- Cell cycle regulation of c-Jun N-terminal kinase activity at the centrosomes. (2001) (41)
- The structure and behavior of the nucleolus organizers in mammalian cells (2004) (41)
- Autoantibodies from a patient with scleroderma CREST recognized kinetochores of the higher plant Haemanthus. (1990) (40)
- Morphological and biochemical responses of cultured thyroid cells to thyrotropin. (1985) (40)
- Cytoplasmic microtubules in transformed mouse × nontransformed human cell hybrids: Correlation with in vitro growth (1977) (39)
- Intracellular protein binding to asbestos induces aneuploidy in human lung fibroblasts. (2006) (38)
- Centromeres and kinetochores: integrated domains on eukaryotic chromosomes. (1990) (38)
- Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant (2013) (38)
- Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle (1996) (36)
- Structure of the mitotic apparatus and chromosomes after hypotonic treatment of mammalian cells in vitro. (1980) (35)
- Ultrastructure of mammalian chromosome aberrations. (1975) (35)
- Effects of nucleic acid specific dyes on centrioles of mammalian cells. (1976) (33)
- CENP-G: a new centromeric protein that is associated with the alpha-1 satellite DNA subfamily. (1998) (33)
- ELECTRON-DENSE STRUCTURES IN MITOCHONDRIA INDUCED BY SHORT-TERM ETHIDIUM BROMIDE TREATMENT (1973) (33)
- Microtubule Complexes Correlated with Growth Relaxation Times in Human Breast Cancer Cells (1982) (32)
- Evidence of Lysogeny in Derivatives of Escherichia coli (1965) (31)
- Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid. (1987) (30)
- Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFβRII (2000) (29)
- Mitotic inhibition and chromosome displacement induced by estradiol in Chinese hamster cells. (1987) (29)
- Neurons from chick embryo cerebrum: Ultrastructural and biochemical development in vitro (1983) (29)
- Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model (1983) (27)
- Cell motility and the cytoskeleton in transition. (2009) (27)
- ULTRASTRUCTURAL STUDIES OF RADIATION-INDUCED CHROMOSOME DAMAGE (1969) (27)
- Asbestos body phagocytosis by human free alveolar macrophages. (1980) (24)
- Cellular and molecular aspects of fiber carcinogenesis (1991) (23)
- Sequence of events in the transformation process in cells infected with a temperature-sensitive transformation mutant of Moloney murine sarcoma virus. (1981) (21)
- Neuronal cytoskeletal alterations evoked by a platelet-activating factor (PAF) analogue. (1999) (21)
- EVIDENCE FOR SUBCHROMATID ORGANIZATION IN MARSUPIAL CHROMOSOMES : I. Light and Electron Microscopy of X-Ray-Induced Side-Arm Bridges (1969) (20)
- Identification of cytokeratin antigens in Novikoff ascites hepatoma. (1982) (20)
- The cytoskeleton: a perspective. (1982) (20)
- Centromeric DNA cloned from functional kinetochore fragments in mitotic cells with unreplicated genomes. (1993) (18)
- The centromere and aneuploidy: I. Caffeine-induced detachment and fragmentation of kinetochores of mammalian chromosomes. (1989) (17)
- MICROTUBULE DISTRIBUTION IN THE ANAPHASE SPINDLE OF PRIMARY SPERMATOCYTES OF A CRANE FLY (NEPHROTOMA SUTURALIS) (1977) (17)
- Scanning electron microscopic examination of human asbestos bodies. (1980) (17)
- Localization of human SMC1 protein at kinetochores (2004) (17)
- Embedding in Situ (1973) (16)
- Localization of tubulin in the mitotic apparatus of mammalian cells by immunofluorescence and immunoelectron microscopy (1977) (16)
- Effects of actinomycin D on spermatogenesis in the Chinese hamster. (1973) (16)
- Differential binding of tritiated actinomycin to the nuclei of mammalian spermatogenic cells in vivo. (1974) (15)
- Ultrastructure of mammalian spermiogenesis. I. A tubular complex in developing sperm of the cottontop marmoset Sequinus oedipus. (1970) (14)
- Ultrastructure of mammalian spermiogenesis. II. Elimination of the nuclear membrane. (1971) (14)
- Toward a structural and molecular definition of the kinetochore. (1990) (13)
- Mitosis in human leukemic leukocytes during colcemid inhibition and recovery. (1972) (13)
- Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide. (1992) (13)
- Ultrastructure of Deoxyribonucleic Acid-Membrane Associations in Escherichia coli (1970) (12)
- Differential immunofluorescent labeling of chromosomes with antisera specific for single strand DNA. (1972) (11)
- Relevance of histone acetylation and replication timing for deposition of centromeric histone CENP-A. (2003) (11)
- Chromosomes, kinetochores and the microtubule connection. (1991) (11)
- Organization of the cytoplasm. (1982) (11)
- Action of rotenone and related respiratory inhibitors on mammalian cell division. 2 Ultrastructural studies. (1976) (10)
- Microinjected Kinetochore Antibodies Interfere with Chromosome Movement in Meiotic and Mitotic Mouse Oocytes (2002) (10)
- Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties. (1980) (9)
- Electron microscopic cytochemical study of phosphatases during spermiogenesis in Chinese hamster. (1974) (9)
- Human antibodies and their use for the study of chromosome organization. (1986) (9)
- REGULATION OF SPINDLE MICROTUBULE ASSEMBLY-DISASSEMBLY: LOCALIZATION AND POSSIBLE FUNCTIONAL ROLE OF CALCIUM DEPENDENT REGULATOR PROTEIN (1978) (9)
- A framework for image-based classification of mitotic cells in asynchronous populations. (2012) (9)
- Effect of Miracil D on Marker Frequency Ratio and Cytotoxicity in Bacillus subtilis (1970) (8)
- Localization of the centriole and keratin intermediate filaments in PtK1 cells by double immunofluorescence. (1984) (8)
- Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro (1982) (8)
- Double fluorescent staining for the separate demonstration of chromosomes and microtubules in mitotic cells in vitro. (1978) (7)
- Microtubule complexes correlated with growth rate and water proton relaxation times in human breast cancer cells. (1982) (7)
- The Cytoskeleton: An Intermediate in the Expression of the Transformed Phenotype in Malignant Cells (1982) (7)
- Mammalian Chromosome Structure: Ultrastructural Aspects of Specialized Regions and Chromosome Aberrations1 (1975) (7)
- A quantitative ultrastructural study of microtubules in transformed and nontransformed cells in vitro. (1981) (7)
- A Silver-Aldehyde Reaction for Studies of Chromosome Ultrastructure (1964) (7)
- Cytoplasmic microtubule assembly-disassembly in enucleated cells and regenerating karyoplasts. (1980) (6)
- Synthesis of azidotubulin: a photoaffinity label for tubulin-binding proteins. (1989) (6)
- Chapter 14 – Localization of Calmodulin in Tissue Culture Cells (1982) (5)
- Effects of cystic fibrosis serum ciliary inhibitor on oyster gill ultrastructure: analysis by scanning and transmission electron microscopy. (1976) (5)
- Identification of microtubules in normal and diabetic rabbit islets grown in monolayer culture. (1982) (5)
- Deoxyribonucleic Acid of Anaplasma marginale (1972) (5)
- Action of rotenone and related respiratory inhibitors on mammalian cell division. 1 Cell kinetics and biochemical aspects. (1976) (4)
- Identification of a 40 × 10(3) Mr centromere-associated protein in cultured mammalian cells (1990) (4)
- Which cytoskeletal determinants preserve ontogenetic history? (1981) (4)
- INDUCTION OF MICROTUBULE ASSEMBLY IN SITU FROM UNPOLYMERIZED TUBULIN POOLS IN SV40 TRANSFORMED 3T3 CELLS (1982) (4)
- X ray imaging microscope for cancer research (1991) (3)
- Potassium inhibition of transforming protein P85gag‐mos and reversal of the transformed phenotype in 6m2 cells (1988) (3)
- The microtubule cytoskeleton in normal and transformed cells in vitro. (1980) (3)
- The occurrence of lysosome-like structures in sickling erythrocytes. (1970) (2)
- Microtubules are not altered in the dystrophic chicken. (1986) (2)
- Isolation of a kinetochore-centromere fraction from HeLa metaphase chromosomes. (1986) (2)
- Monoclonal antibody with specificity to a conserved epitope in the C-terminal domain of histone H1 variants. (1991) (2)
- Elusive nucleoskeleton visualized in live cells. (2004) (1)
- The centromere and aneuploidy: II. Drug induced detachment and fragmentation of kinetochores of mammalian chromosomes. (1990) (1)
- Design and analysis of a water window imaging x-ray microscope (1991) (1)
- Variationsin Cell FormandCytoskeletonin HumanBreastCarcinomaCells in Vitro (1980) (1)
- Electron Microscopic Cytochemical Study of Phosphatases (1974) (1)
- An imprint-spreading procedure for electron microscopy of selected cells in situ. (1970) (1)
- Aurora‐C phosphorylates and regulates Borealin and CENP‐A during mitosis (2008) (0)
- Tubulin and actin immunofluorescence as an aid in detecting cell transformation in vitro. (1978) (0)
- Fractionation and from Mammalian Initial Characterization of the Metaphase Chromosomes Kinetochore (2002) (0)
- Cytoplasmic microtubules innormalandtransformed cells in culture: Analysis bytubulin antibody immunofluorescence (1975) (0)
- Analysis of Centrosome Replication Events in Mammalian Cells (1994) (0)
- Subject Index Vol. 26, 1980 (1980) (0)
- Control of microtubule Aassembly-disassembly by calcium-dependentregulator protein ( immunofluorescence / calcium-binding proteins / mitosis ) (0)
- CHAPTER 3 – Embedding in Situ1 (1973) (0)
- Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant (2013) (0)
- Discussion: Perspectives and Future Directions Regarding the Mechanisms of Aneuploidy (1985) (0)
- Ninth aspen cancer conference: Mechanisms of toxicity and carcinogenesis (1995) (0)
- Variationsin Cell Formand Cytoskeletonin HumanBreastCarcinomaCells in Vitro ' (2006) (0)
- NORMAL MICROTUBULE (MT) ASSEMBLY BY CHEDIAK-HIGASHI (CH) PMNs (1984) (0)
- Conference Summary (1986) (0)
- Micro tubules in dystrophic chicken cells in vitro (1981) (0)
- The condensin complex interacts with a human homologue of the S cerevisiae lifespan limiting protein Sir2 (2000) (0)
- Identification of a 40 x 10(3) Mr centromere-associated protein in cultured mammalian cells. (1990) (0)
- Micro tubules and transformation a quantitative electron microscope study (1980) (0)
- Cultures of pancreatic cells from dbdb mice. Abstr. (1979) (0)
- EVIDENCE FOR SUBCHROMATID ORGANIZATION IN MARSUPIAL CHROMOSOMES (1969) (0)
- Genomic stability and the mechanisms of chromatid separation in mammalian cells. (1998) (0)
- The development and application of a silver-aldehyde reaction for the study of chromosome ultrastructure (1964) (0)
- Cell cycle-dependent expression and subcellular localization of human barren-1 (HCAP-H). (1999) (0)
- Mitotic checkpoints, MUGs and kinetochores (2013) (0)
- Effects of griseofulvin on mitosis and microtubules in mammalian cells in vitro (1978) (0)
- Aneuploidy (2019) (0)
- Tao-Chiuh Hsu (1980) (0)
- International cell biology, 1976-1977 : papers presented at the first International Congress on Cell Biology, Boston, Massachusetts, 1976 (1977) (0)
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