Bengt Bertil Samuelsson

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#1436

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#2415

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Biochemistry

#102

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#131

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Bengt Bertil Samuelsson

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#1533

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#2767

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Logic

#235

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#495

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Bengt Bertil Samuelsson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. (1975) (2982)
Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. (1983) (2691)
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. (1987) (2118)
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. (1974) (1246)
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. (1999) (1004)
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. (1981) (981)
Leukotrienes are potent constrictors of human bronchi (1980) (953)
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. (1974) (890)
Leukotriene C: a slow-reacting substance from murine mastocytoma cells. (1979) (874)
Advances in prostaglandin and thromboxane research (1976) (860)
Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187. (1979) (702)
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. (1984) (653)
On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase. (1967) (582)
Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. (1979) (559)
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. (1976) (556)
Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. (1973) (543)
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis. (1975) (535)
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target (2007) (525)
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides (1976) (517)
Ribonuclease activity and RNA binding of recombinant human Dicer (2002) (493)
Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. (1979) (474)
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. (1974) (471)
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis (2003) (470)
5-Lipoxygenase: regulation of expression and enzyme activity. (2007) (439)
THE ENZYMATIC FORMATION OF PROSTAGLANDIN E2 FROM ARACHIDONIC ACID PROSTAGLANDINS AND RELATED FACTORS 32. (1964) (429)
Prostaglandin F 2 identified as a luteolytic hormone in sheep. (1972) (424)
PROSTAGLANDINS AND RELATED FACTORS: XIX. THIN-LAYER CHROMATOGRAPHY OF PROSTAGLANDINS. (1964) (405)
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence. (1981) (400)
Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. (1979) (379)
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease. (2015) (361)
On the Metabolism of Prostaglandins E1 and E2 in Man (1971) (345)
On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha. (1967) (344)
Stereospecific total synthesis of a "slow reacting substance" of anaphylaxis, leukotriene C-1 (1980) (326)
Phospholipid precursors of prostaglandins. (1968) (301)
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. (1975) (298)
Prostaglandins and Thromboxanes (1977) (282)
Prostaglandins in human seminal plasma. Prostaglandins and related factors 46. (1966) (272)
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. (1986) (272)
Structure of leukotriene C. Identification of the amino acid part. (1979) (263)
Identification and biological activity of novel ω‐oxidized metabolites of leukotriene B4 from human leukocytes (1981) (259)
The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandin-delta 13-reductase in tissues of the swine. (1971) (258)
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells. (1980) (250)
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. (1984) (250)
PROSTAGLANDINS AND RELATED FACTORS. 28. METABOLISM OF PROSTAGLANDIN E1 IN GUINEA PIG LUNG: THE STRUCTURES OF TWO METABOLITES. (1964) (249)
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. (1967) (240)
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. (2006) (240)
The structure of prostaglandin E F1 and F2. (1962) (240)
The leukotrienes: a new group of biologically active compounds (1981) (237)
Prostaglandins and thromboxanes. (1978) (235)
Introduction of a nomenclature: leukotrienes. (1979) (234)
Biological profile of leukotrienes C4 and D4. (1980) (228)
Thromboxane generation by human peripheral blood polymorphonuclear leukocytes (1978) (228)
Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. (1984) (225)
Prostaglandins and Related Factors 15. THE STRUCTURES OF PROSTAGLANDIN E1, F1α, AND F1β (1963) (220)
Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. (1982) (219)
Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid. (1986) (219)
On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. (1985) (219)
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. (1984) (213)
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases. (2000) (212)
Leukotrienes and Slow Reacting Substance of Anaphylaxis (SRS‐A) (1980) (210)
Stimulation of Renin Release from Rabbit Renal Cortex by Arachidonic Acid and Prostaglandin Endoperoxides (1976) (203)
Chapter 4 Coexistence of neuronal messengers — an overview (1986) (202)
ON THE INCORPORATION OF OXYGEN IN THE CONVERSION OF 8, 11, 14-EICOSATRIENOIC ACID TO PROSTAGLANDIN E1. (1965) (201)
Advances in inflammation research (1979) (198)
Prostaglandin endoperoxides. VII. Novel transformations of arachidonic acid in guinea pig lung. (1974) (195)
Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey (1982) (193)
Co-oxygenation of organic substrates by the prostaglandin synthetase of sheep vesicular gland. (1975) (186)
Radioimmunoassay for Thromboxane B2 (1976) (181)
Prostaglandin endoperoxides IV. Effects on smooth muscle. (1975) (180)
ISOLATION AND IDENTIFICATION OF PROSTAGLANDINS FROM HUMAN SEMINAL PLASMA. 18. PROSTAGLANDINS AND RELATED FACTORS. (1963) (180)
Molecular cloning and amino acid sequence of human 5-lipoxygenase. (1988) (174)
Human Microsomal Prostaglandin E Synthase-1 (2003) (174)
ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma (2008) (173)
Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets. (1975) (173)
Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes. (2002) (166)
Enzymes involved in the biosynthesis of leukotriene B4. (1989) (166)
Stimulation of human leukocyte degranulation by leukotriene B4 and its ω‐oxidized metabolites (1981) (163)
On the Metabolism of Prostaglandin F2α in Female Subjects (1971) (162)
Biosynthesis of prostaglandins from arachidonic acid in guinea pig lung. Prostaglandins and related factors. 38. (1965) (161)
Characterization of the human 5-lipoxygenase gene. (1989) (158)
Leukotrienes in the rat central nervous system. (1984) (158)
Arachidonic acid metabolism: role in inflammation. (1991) (152)
On the formation and effects of thromboxane A2 in human platelets. (1976) (151)
Dicer is required for chromosome segregation and gene silencing in fission yeast cells (2002) (151)
Arachidonic acid epoxides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acids. (1983) (150)
Lipoxin A. Stereochemistry and biosynthesis. (1986) (149)
Extracellular signal‐regulated kinases phosphorylate 5lipoxygenase and stimulate 5‐lipoxygenase product formation in leukocytes (2002) (148)
The relation between fertility and prostaglandin content of seminal fluid in man. (1970) (145)
Formation of novel hydroxylated eicosatetraenoic acids in preparations of human polymorphonuclear leukocytes (1981) (144)
Leukotrienes and other lipoxygenase products. (1986) (144)
Quantitative gas chromatography of prostaglandin E1 at the Nanogram level: use of deuterated carrier and multiple-ion analyzer. (1970) (143)
A novel leukotriene produced by stimulation of leukocytes with formylmethionylleucylphenylalanine. (1982) (141)
Characterization of the human 5-lipoxygenase gene promoter. (1990) (140)
Leukotriene B4: a highly potent and stereospecific factor stimulating migration of polymorphonuclear leukocytes. (1980) (137)
Nomenclature for leukotrienes. (1980) (137)
Cyclic AMP inhibits synthesis of prostaglandin endoperoxide (PGG2) in human platelets. (1976) (137)
Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. (2010) (136)
15-Hydroxy-prostanoate dehydrogenase. Prostaglandins as substrates and inhibitors. (1969) (134)
Metabolism of leukotriene A4 by human erythrocytes. A novel cellular source of leukotriene B4. (1984) (132)
Leukotriene A: stereochemistry and enzymatic conversion to leukotriene B. (1980) (132)
Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3. (1995) (130)
Role of Basic Science in the Development of New Medicines: Examples from the Eicosanoid Field (2012) (127)
Increased nerve stimulation induced release of noradrenaline from the rabbit heart after inhibition of prostaglandin synthesis. (1971) (125)
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase. (1986) (125)
IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression (2001) (120)
Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. (1998) (120)
Leukotriene A4 hydrolase: an epoxide hydrolase with peptidase activity. (1990) (119)
The importance of hydroperoxide activation for the detection and assay of mammalian 5‐lipoxygenase (1986) (117)
Interaction of 5-lipoxygenase with cellular proteins. (1999) (114)
Leukotriene B4 — a stereospecific stimulator for release of lysosomal enzymes from neutrophils (1981) (114)
Molecular cloning of a 12-lipoxygenase cDNA from rat brain. (1993) (113)
The discovery of the leukotrienes. (2000) (113)
On the expression and regulation of 5-lipoxygenase in human lymphocytes. (1992) (112)
From studies of biochemical mechanism to novel biological mediators: Prostaglandin endoperoxides, thromboxanes, and leukotriences (1983) (112)
Leukotriene A. Isolation from human polymorphonuclear leukocytes. (1980) (111)
Raven Press, New York (1995) (1996) (110)
Prevention of simian immunodeficiency virus, SIVsm, or HIV‐2 infection in cynomolgus monkeys by pre‐ and postexposure administration of BEA‐005 (1997) (109)
Analyses of prostaglandins in human semen. Prostaglandins and related factors 44. (1966) (108)
Molecular cloning and amino acid sequence of leukotriene A4 hydrolase. (1987) (107)
Leukotriene A4 hydrolase: a zinc metalloenzyme. (1990) (107)
Prostaglandins, thromboxanes, and leukotrienes: formation and biological roles. (1979) (102)
Methods for quantitative analysis of PGF2 , PGE2, 9 , 11 -dihydroxy-15-keto-prost-5-enoic acid and 9 , 11 , 15-trihydroxy-prost-5-enoic acid from body fluids using deuterated carriers and gas chromatography--mass spectrometry. (1973) (102)
Mass spectrometric determination of picomole amounts of prostaglandins E 2 and F 2 using synthetic deuterium labeled carriers. (1971) (101)
Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells (2009) (101)
THE ENZYMATIC CONVERSION OF ESSENTIAL FATTY ACIDS INTO PROSTAGLANDINS. (1964) (98)
Metabolism of 8,11,14-eicosatrienoic acid in human platelets. (1976) (98)
Reversible, calcium-dependent membrane association of human leukocyte 5-lipoxygenase. (1987) (97)
SMOOTH MUSCLE STIMULATING LIPIDS IN SHEEP IRIS. THE IDENTIFICATION OF PROSTAGLANDIN F 2A. PROSTAGLANDINS AND RELATED FACTORS 21. (1964) (96)
PROSTAGLANDINS AND RELATED FACTORS. 27. SYNTHESIS OF TRITIUM-LABELED PROSTAGLANDIN E1 AND STUDIES ON ITS DISTRIBUTION AND EXCRETION IN THE RAT. (1964) (96)
5-Lipoxygenase Interacts with Coactosin-like Protein* (2001) (96)
Synthesis and biological properties of a 9,11-azo-prostanoid: highly active biochemical mimic of prostaglandin endoperoxides. (1975) (96)
Leukotriene C4 as a mediator of luteinizing hormone release from rat anterior pituitary cells. (1985) (96)
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis. (1991) (94)
Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production (2006) (93)
Prostaglandin F2α Receptor in Ovine corpora lutea (1974) (93)
Formation of lipoxin A by granulocytes from eosinophilic donors (1987) (92)
Increased levels of cyclooxygenase‐2 mRNA in the rat spinal cord after peripheral inflammation: an in situ hybridization study (1997) (92)
Extraction and chromatographic procedures for purification of prostaglandins, thromboxanes, prostacyclin, and their metabolites. (1978) (92)
Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis. (1987) (92)
SYNTHESIS OF TRITIUM-LABELED PROSTAGLANDIN E-2 AND STUDIES ON ITS METABOLISM IN GUINEA PIG LUNG. 37. PROSTAGLANDINS AND RELATED FACTORS. (1965) (91)
Action of novel eicosanoids lipoxin A and B on human natural killer cell cytotoxicity: effects on intracellular cAMP and target cell binding. (1985) (91)
Leukotrienes: a new class of mediators of immediate hypersensitivity reactions and inflammation. (1983) (90)
5-lipoxygenase: regulation and possible involvement in atherosclerosis. (2007) (89)
Novel leukotrienes: products formed by initial oxygenation of arachidonic acid at C-15. (1981) (89)
Formation and action of prostaglandin endoperoxides in the isolated human umbilical artery. (1976) (88)
The leukotrienes: an introduction. (1982) (88)
On the stereochemistry and biosynthesis of lipoxin B. (1986) (88)
Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action. (1987) (88)
Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. (1987) (87)
Characterization of human 12-lipoxygenase genes. (1992) (87)
Microsomal prostaglandin E synthase‐1 and 5‐lipoxygenase: potential drug targets in cancer (2010) (86)
On the nature of the 5-lipoxygenase reaction in human leukocytes: characterization of a membrane-associated stimulatory factor. (1985) (86)
Identification of leukotriene C-1 as a major component of slow-reacting substance from rat mononuclear cells. (1980) (85)
From studies of biochemical mechanism to novel biological mediators: prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel Lecture, 8 December 1982. (1983) (84)
On the organization and mechanism of prostaglandin synthetase. (1973) (83)
Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. (1984) (83)
Biosynthesis of 19-hydroxy-prostaglandin A1. (1969) (81)
Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes. (2001) (79)
The structure of the major urinary metabolite of prostaglandin E2 in man. (1969) (79)
Biosynthesis of prostaglandins. (1972) (78)
Transforming growth factor beta upregulates 5-lipoxygenase activity during myeloid cell maturation. (1993) (78)
On the specificity of the lipoxidase catalyzed oxygenation of unsaturated fatty acids. (1965) (78)
Identification of a component of rat mononuclear cell SRS as leukotriene D. (1980) (76)
Measurement of prostaglandins, thromboxanes, prostacyclin and their metabolites by gas liquid chromatography--mass spectrometry. (1978) (75)
Endogenous levels of 15-keto-dihydro-prostaglandins in human plasma. Parameters for monitoring prostaglandin synthesis. (1974) (75)
On the metabolism of prostaglandin F 2 in female subjects. II. Structures of six metabolites. (1971) (74)
PROSTAGLANDIN-F2α RECEPTOR IN HUMAN CORPORA LUTEA (1974) (74)
On the metabolism of prostaglandins E 1 and E 2 in man. (1971) (74)
Autoradiographic distribution studies of 3H-labeled prostaglandin E1 in mice. Prostaglandins and related factors 31. (1965) (72)
Occurrence and properties of a prostaglandin F2alpha receptor in bovine corpora lutea. (1975) (71)
Thromboxane Synthesis and the Platelet Release Reaction in Bernard‐Soulier Syndrome, Thrombasthenia Glanzmann and Hermansky‐Pudlak Syndrome (1977) (71)
Leukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296. (1992) (70)
The role of prostaglandin endoperoxides and thromboxanes in platelet aggregation. (1976) (70)
The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes (1980) (70)
Quantitative measurement of prostaglandins and thromboxanes: general considerations. (1978) (70)
Omega-hydroxylation of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid in human polymorphonuclear leukocytes. (1984) (68)
Leukotriene A4: enzymatic conversion to leukotriene C4. (1980) (67)
Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight‐binding inhibitors (2002) (67)
Expression of 5-lipoxygenase in differentiating human skin keratinocytes. (1995) (66)
5-lipoxygenase expression in dendritic cells generated from CD34(+) hematopoietic progenitors and in lymphoid organs. (2000) (66)
The Structure of the Main Urinary Metaboilite of Prostaglandin F2α in the Guinea Pig (1969) (66)
Absolute Configuration of the Prostaglandins (1966) (66)
Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75. (2001) (66)
Development of selective tight-binding inhibitors of leukotriene A4 hydrolase. (1993) (66)
Bile Acids and Steroids 96. ON THE MECHANISM OF THE BIOLOGICAL FORMATION OF DEOXYCHOLIC ACID FROM CHOLIC ACID (1960) (65)
15-Lipoxygenase in human platelets. (1985) (65)
Biosynthesis of 9α,15-Dihydroxy-11-ketoprost-13-enoic Acid (1968) (64)
Metabolism of prostaglandin E2 in guinea pig liver. II. Pathways in the formation of the major metabolites. (1971) (63)
Regulation of 5-lipoxygenase enzyme activity. (2005) (63)
Oxidative Processes and Antioxidants (1995) (63)
Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm (2010) (62)
Leukotrienes: mediators of allergic reactions and inflammation. (1981) (62)
Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males (2017) (61)
Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. (1980) (61)
Transformation of 15‐hydroperoxy‐5,9,11,13‐eicosatetraenoic acid into novel leukotrienes (1981) (61)
5-Lipoxygenase expression in Langerhans cells of normal human epidermis. (1998) (60)
Mutations at the C-terminal isoleucine and other potential iron ligands of 5-lipoxygenase. (1995) (60)
Regional distribution of leukotriene and mono‐hydroxyeicosatetraenoic acid production in the rat brain Highest leukotriene C4 formation in the hypothalamus (1987) (60)
The structure of a urinary metabolite of prostaglandin F2a in man. (1969) (58)
Isolation of prostaglandin E1 from human seminal plasma. Prostaglandins and related factors. 11. (1962) (58)
Impaired platelet response to thromboxane-A2 and defective calcium mobilization in a patient with a bleeding disorder. (1981) (57)
Involvement of endoperoxides and thromboxanes in anaphylactic reactions. (1976) (57)
On the mechanism of biosynthesis of leukotrienes and related compounds (1982) (57)
QUANTITATIVE DETERMINATION OF PROSTAGLANDINS IN HUMAN SEMEN. (1964) (56)
Thromboxane a2: biosynthesis and effects on platelets. (1982) (55)
Light emission during the action of prostaglandin synthetase. (1974) (55)
Iron content of human 5-lipoxygenase, effects of mutations regarding conserved histidine residues. (1993) (54)
Prostaglandins and Related Factors. 17.1 The Structure of Prostaglandin E32 (1963) (54)
p38 MAP kinase mediates stress‐induced leukotriene synthesis in a human B‐lymphocyte cell line (2001) (53)
Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378. (1996) (53)
Cyclooxygenase-1 and cyclooxygenase-2 expression in rat kidney and adrenal gland after stimulation with systemic lipopolysaccharide (2001) (52)
Metabolism of leukotriene A4 by an enzyme in blood plasma: a possible leukotactic mechanism. (1983) (52)
Detection of leukotriene A4 as an intermediate in the biosynthesis of leukotrienes C4 and D4 (1980) (52)
Regulation of the human leukocyte 5-lipoxygenase: stimulation by micromolar Ca2+ levels and phosphatidylcholine vesicles. (1988) (51)
Preparation of Ursodeoxycholic Acid and 3alpha,7beta,12alpha-Trihydroxycholanic Acid. Bile Acids and Steroids 94. (1960) (51)
A comparison of the vasodepressor effects of the cyclic endoperoxides PGG2 and PGH2 with those of PGD2 and PGE2 in hypertensive and normotensive rats (1976) (50)
The action of lipoxin-A on glomerular microcirculatory dynamics in the rat. (1987) (50)
Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation. (1995) (50)
Identification of prostaglandins in the gorgonian, Plexaura homomalla. (1972) (49)
An elucidation of the arachidonic acid cascade. Discovery of prostaglandins, thromboxane and leukotrienes. (1987) (49)
Novel Biological Transformations of 8,11,14-Eicosatrienoic Acid (1966) (49)
Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system. (1989) (48)
On the induction of 5-lipoxygenase expression and activity in HL-60 cells: effects of vitamin D3, retinoic acid, DMSO and TGF beta. (1994) (48)
Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities). (1988) (47)
The effects of lipoxin A and lipoxin B on functional responses of human granulocytes. (1987) (47)
Cloning of the cDNA for human 12-lipoxygenase. (1990) (46)
A method for measuring the unstable thromboxane A2: radioimmunoassay of the derived mono-O-methyl-thromboxane B2. (1976) (46)
Prostaglandins and related factors. XLII. Metabolism of prostaglandin E3 in guinea pig lung. (1965) (46)
Mutagenesis of some conserved residues in human 5-lipoxygenase: Effects on enzyme activity (1992) (46)
Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor (2014) (46)
Inhibition of basal and hormone-stimulated adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide prostaglandin H2. (1975) (45)
Leukotriene A4 hydrolase: Selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375 (2002) (45)
THE ORIGIN OF OXYGEN INCORPORATED DURING THE BIOSYNTHESIS OF PROSTAGLANDIN E-1. (1965) (45)
Prostaglandin levels in normal and transformed baby-hamster-kidney fibroblasts. (1973) (45)
Calcitriol and transforming growth factor-beta upregulate 5-lipoxygenase mRNA expression by increasing gene transcription and mRNA maturation. (1998) (44)
Circulating hydroxy fatty acids in familial Mediterranean fever. (1985) (44)
Leukotrienes: a novel group of biologically active compounds. (1982) (44)
GM‐CSF– and M‐CSF–primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures (2017) (42)
Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase. (1980) (42)
Leukotriene C4 binding sites in the rat central nervous system. (1986) (42)
Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102. (2009) (42)
Introduction: new trends in prostaglandin research. (1976) (41)
Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase. (1995) (41)
Preparation, isolation, and characterization of a derivative of malonaldehyde. (1968) (41)
On the metabolism of prostaglandins E 1 and E 2 in the guinea pig. (1972) (40)
Novel transformations of prostaglandin endoperoxides: formation of thromboxanes. (1976) (40)
Oculoparalytic Illusion : Visual-Field Dependent Spatial Mislocalizations by Humans Partially Paralyzed with Curare (2006) (40)
Additions and Corrections - Stereospecific Total Synthesis of a "Slow Reacting Substance" of Anaphylaxis Leukotriene C-1 (1980) (40)
The structure of a urinary metabolite of prostaglandin E2 in the guinea pig. (1969) (39)
Mutation of a Critical Arginine in Microsomal Prostaglandin E Synthase-1 Shifts the Isomerase Activity to a Reductase Activity That Converts Prostaglandin H2 into Prostaglandin F2α* (2009) (39)
Prostaglandins of human seminal plasma. (1963) (39)
Human Dicer C-terminus functions as a 5-lipoxygenase binding domain. (2009) (39)
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis (2014) (39)
The physiological role of prostaglandin F2alpha in corpus luteum regression. (1973) (39)
Prostaglandins and thromboxanes: biochemical and physiological considerations. (1978) (39)
Maintenance of the tone of the human umbilical artery by prostaglandin and thromboxane formation. (1976) (39)
Development and mass spectrometric evaluation of a radioimmunoassay for 9α, 11α‐Dihydroxy‐15‐ketoprost‐5‐enoic acid (1972) (38)
Prostagland Endoperoxides. NovelTransformations ofArachidonic (1974) (38)
Leukotriene A 4 Hydrolase in Human Leukocytes (2001) (38)
Isolation and identification of lipoxygenase products from the rat central nervous system. (1987) (37)
11-Trans leukotriene C: a naturally occurring slow reacting substance. (1980) (37)
Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4[S] (2016) (36)
Recombinant mouse leukotriene A4 hydrolase: a zinc metalloenzyme with dual enzymatic activities. (1991) (35)
Selective inhibition of prostaglandin synthetase by a bicyclo[2.2.1]heptene derivative. (1971) (35)
A method for determination of prostaglandins in human seminal fluid. (1969) (35)
Simple, stereocontrolled total synthesis fof a biologically active analog of the prostaglandin endoperoxides (PGH2, PGG2) (1976) (34)
Potato arachidonate 5-lipoxygenase: purification, characterization, and preparation of 5(S)-hydroperoxyeicosatetraenoic acid. (1990) (34)
Leukotriene A4 Hydrolase, Mutation of Tyrosine 378 Allows Conversion of Leukotriene A4 into an Isomer of Leukotriene B4* (1996) (34)
Quantitative studies on the synthesis in vivo of prostaglandins in the rat. Cold stress induced stimulation of synthesis. (1971) (34)
THE STRUCTURE OF A URINARY METABOLITE OF PROSTAGLANDIN F1-ALPHA IN THE RAT. PROSTAGLANDINS AND RELATED FACTORS 29. (1965) (33)
Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences. (2000) (33)
Isolation and structure of a new prostaglandin from human seminal plasma. Prostaglandins and related factors 43. (1965) (33)
The Leukotrienes, Highly Biologically Active Substance Involved in Allergy and Inflammation (1982) (32)
Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development (2011) (32)
Evidence for a 5(6)‐epoxytetraene intermediate in the biosynthesis of lipoxins in human leukocytes (1986) (32)
Serum factors regulate 5-lipoxygenase activity in maturating HL60 cells. (1993) (32)
Stabilization of purified human 5-lipoxygenase with glutathione peroxidase and superoxide dismutase. (1994) (31)
Nomenclature of lipoxins and related compounds derived from arachidonic acid and eicosapentaenoic acid. (1987) (31)
Interactions between prostaglandin analogues and a receptor in bovine Corpora lutea. Correlation of dissociation constants with luteolytic potencies in hamsters. (1975) (31)
Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells. (2005) (30)
Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z,10E,12E- icosatetraenoic acid. (1984) (30)
Isolation of Prostaglandin E1 from Calf Thymus. Prostaglandins and Related Factors. 20. (1963) (30)
Localization of a prostaglandin F2alpha receptor in bovine Corpus luteum plasma membranes. (1976) (30)
Letter: Mechanism of the anti-aggregating effect of aspirin on human platelets. (1974) (30)
Cyclooxygenase-2 involved in stimulation of renal mechanosensitive neurons. (2000) (29)
2 – OXYGENASES IN FATTY ACID AND STEROID METABOLISM (1974) (29)
Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1. (2019) (29)
TRANSFORMATION OF CHOLIC ACID IN VITRO BY CORYNEBACTERIUM SIMPLEX. BILE ACIDS AND STEROIDS. 132. (1964) (28)
Leukotrienes: a novel group of compounds including SRS-A. (1981) (27)
Mutagenesis of some conserved residues in human 5-lipoxygenase: effects on enzyme activity. (1992) (27)
Metabolism of prostaglandin E 2 in guinea pig liver. (1971) (27)
An Elucidation of the Arachidonic Acid Cascade (2012) (26)
Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4. (1989) (26)
Chapter IV – Structures, Biosynthesis, and Metabolism of Prostaglandins (1970) (26)
Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors (2011) (26)
GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site. (2005) (25)
Chemical modification of leukotriene A4 hydrolase. Indications for essential tyrosyl and arginyl residues at the active site. (1995) (25)
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes. (1995) (25)
Bile acids and steroids. LXXXIII. On the inter-conversion of cholic and deoxycholic acid in the rat. (1959) (25)
Expression of 5-lipoxygenase and biosynthesis of leukotriene B4 in human monomorphonuclear leukocytes. (1993) (25)
Leukotriene A4 hydrolase: structural and functional properties of the active center. (1993) (24)
Molecular cloning and functional characterization of mouse coactosin-like protein. (2002) (24)
Recent Advances in Prostaglandin, Thromboxane, and Leukotriene Research (1997) (24)
THE BIOSYNTHESIS OF PROSTAGLANDIN E1 STUDIED WITH SPECIFICALLY 3H-LABELLED 8,11,14-EICOSATRIENOIC ACIDS. (1965) (23)
A dynamic Asp–Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase (2016) (23)
Hemoprotein catalysis of leukotriene formation. (1984) (22)
Leukotrienes and related compounds. (1985) (22)
FROM STUDIES OF BIOCHEMICAL MECHANISMS TO NEW BIOLOGICAL MEDIATORS: PROSTAGLANDIN ENDOPEROXIDES, THROMBOXANES, AND LEUKOTRIENES (1984) (22)
Stimulation of human leukocyte degranulation by leukotriene B4 and its omega-oxidized metabolites. (1981) (22)
Leukotriene C4-induced cyclic nucleotide changes and contractile response in guinea pig trachea. (1982) (22)
Decreased Rate of Metabolism Induced by a Shift of the Double Bond in Prostaglandin F2α from the 5 to the 4 Position (1976) (21)
The content of different prostaglandins in human seminal fluid and their threshold doses on the human myometrium. (1966) (21)
Structure and Synthesis of a Derivative of Prostaglandin E1. Prostaglandins and Related Factors 16. (1963) (21)
Bile acids and steroids. LXXXII. On the mechanism of deoxycholic acid formation in the rabbit. (1959) (21)
A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes. (1987) (21)
Disparate pathways of prostaglandin biosynthesis in coral and mammalian systems (1975) (21)
Prostaglandins, thromboxanes, and polymorphonuclear leukocytes (1977) (20)
Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis (2017) (20)
On the biosynthesis of cerebrosides containing 2-hydroxy acids. Mass spectrometric evidence for biosynthesis via the ceramide pathway. (1972) (19)
Structure of a deoxyprostaglandin in man. (1972) (19)
On the Metabolism of Chenodeoxycholic Acid in the Rat. Bile Acids and Steroids. 85. (1959) (19)
Effect of Leucotrienes C4, D4, Prostacyclin and Thromboxane A2 on isolated human cerebral arteries (2005) (18)
Investigation of the inhibition of leukotriene A4 hydrolase. (1995) (18)
Quantitative analysis of prostaglandins and thromboxanes by mass spectrometric methods. (1976) (18)
A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity. (2014) (17)
Prostaglandin endoperoxides and thromboxanes: role in platelets and in vascular and respiratory smooth muscle. (1976) (17)
Transformation of Arachidonic Acid by Rabbit Polymorphonwclear Leukocytes (2001) (17)
THE ROLE OF PROSTAGLANDIN ENDOPEROXIDES AND THROMBOXANES AS BIOREGULATORS (1977) (17)
Appearance of an arachidonic acid 15‐lipoxygenase pathway upon differentiation of the human promyelocytic cell‐line HL‐60 (1985) (17)
Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. (1991) (16)
MECHANISMS OF BILE ACID BIOSYNTHESIS STUDIED WITH 3-ALPHA-H3-AND 4-BETA-H3-CHOLESTEROL. BILE ACIDS AND STEROIDS. 144. (1964) (16)
Thromboxane A2 and prostaglandin H2 form covalently linked derivatives with human serum albumin. (1980) (16)
Human leukocyte 5-lipoxygenase: an enzyme possessing dual enzymatic activities and a multicomponent regulatory system. (1987) (16)
[39] A prostaglandin dehydrogenase from pig lung (1969) (15)
Novel Inhibitors of Leukotrienes (1999) (15)
Endogenously generated 5‐hydroperoxyeicosatetraenoic acid is the preferred substrate for human leukocyte leukotriene A4 synthase activity (1987) (15)
IDENTIFICATION OF A SMOOTH MUSCLE-STIMULATING FACTOR IN BOVINE BRAIN. PROSTAGLANDINS AND RELATED FACTORS 25. (1964) (15)
On the biosynthesis of cerebrosides from 2-hydroxy acid ceramides: use of deuterium labeled substrate and multiple ion detector. (1970) (14)
New groups of naturally occurring prostaglandins. (1967) (14)
Leukotriene C4 stimulates LH secretion from rat pituitary cells in vitro. (1984) (14)
Novel Tight‐Binding Inhibitors of Leukotriene A4 Hydrolase. (1992) (13)
Synthesis and Metabolism of 3alpha, 12alpha-Dihydroxy-delta6-cholenic Acid-24-14C. Bile Acids and Steroids 117. (1962) (13)
PROBING THE ACTIVITIES AND MECHANISMS OF LEUKOTRIENE A4 HYDROLASE WITH SYNTHETIC INHIBITORS (1998) (13)
Prostaglandins in human seminal plasma and their effects on human myometrium. (1967) (13)
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm (2018) (13)
Identification and assay of tetranor-prostaglandin E1 in human urine. (1976) (13)
A comparison of the vasodepressor effects of the cyclic effects of the cyclic endoperoxides PGG, and PGH2 with those of PGD2 and PGE2 in hypertensive and normotensive rats. (1976) (12)
Bile acids and steroids. 90. The stereo-chemical course of the reduction of the cholesterol double bond in bile acid formation. (1959) (12)
Solubilization of a prostaglandin F2α receptor in bovine corpora lutea (1975) (12)
Slow-reacting substances and leukotrienes. (1981) (12)
Oxygenation of arachidonic acid into 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acid by rat lung. (1983) (12)
Extraction of PGE from human serum for radioimmunoassay (1972) (12)
Leukocyte arachidonate 5-lipoxygenase: isolation and characterization. (1990) (11)
Probing the Inhibition of Leukotriene-A4 Hydrolase Based on Its Aminopeptidase Activity (1991) (11)
Regulation of 5-Lipoxygenase mRNA Expression in the Human Monocytic Cell Line Mono Mac 6 by Transforming Growth Factor-ß and 1,25-Dihydroxyvitamin D 3 (1999) (11)
Effects of stimulation and inhibition of the renal prostaglandin synthetase system on renin release in vivo and in vitro. (1976) (11)
Letter to the Editor: NMR structure of human coactosin-like protein (2004) (10)
The Metabolism of 7-Ketolithocholic Acid-24-14C in the Rat. Bile Acids and Steroids 70. (1959) (10)
Mutation analysis of the human 5-lipoxygenase C-terminus: support for a stabilizing C-terminal loop. (2005) (10)
Stereochemistry and biosynthesis of lipoxins. (1987) (10)
On the Mechanism of Deoxycholic Acid Formation. (1958) (10)
Biosynthesis and biological activities of lipoxins. (1985) (10)
Leukotriene Biosynthesis a (1991) (10)
Characterization of microsomal, glutathione dependent prostaglandin E synthase. (2002) (10)
Drugs Affecting Leukotrienes and Other Eicosanoid Pathways (1986) (9)
Formation of leukotriene C4 by human leukocytes exposed to monosodium urate crystals (1984) (9)
Transforming growth factor-beta and 1,25-dihydroxyvitamin D3 induce 5-lipoxygenase activity during myeloid cell maturation. (1995) (9)
Gas Liquid Chromatographic—Mass Spectrometric Methods for Quantitation of Prostaglandin Analogs (1976) (9)
Some properties of a prostaglandin F2alpha receptor in corpora lutea. (1976) (9)
5-Lipoxygenase from human leukocytes associates with membrane in the presence of calcium. (1987) (9)
Some recent advances in leukotriene research. (1997) (9)
5-Lipoxygenase activation by MAPKAPK-2 and ERKs. (2003) (9)
Prostaglandins, Thromboxanes and Leukotrienes (1980) (8)
Formation of lipoxygenase products in the rat brain. (1987) (8)
Novel structural and functional properties of leukotriene A4 hydrolase. Implications for the development of enzyme inhibitors. (1994) (8)
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A 4 synthase activities ( 5-hydroperoxyicosatetraenoic acid / 5-hydroxyicosatetraenoic acid / inflammation / enzyme regulation ) (8)
Structural determination of leukotrienes and lipoxins. (1985) (8)
Some practical considerations in the radioimmunoassay of the F prostaglandins (1972) (8)
Nomenclature for thromboxanes. (1978) (8)
Hypertonicity suppresses ionophore‐induced product formation and translocation of 5‐lipoxygenase in human leukocytes (2002) (8)
Albumin stabilizes 14,15‐leukotriene A4 (1983) (7)
Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer. (2021) (7)
New group of leukotrienes formed by initial oxygenation at C-15. (1982) (7)
Leukotriene B4: biosynthesis and role in lymphocytes. (1990) (7)
Metabolism of 3alpha,7beta,12alpha-Trihydroxycholanic Acid in the Rat. Bile Acids and Steroids 95. (1960) (7)
Expression of microsomal glutathione S-transferase type 3 mRNA in the rat nervous system (2002) (7)
Modulation of microRNA processing by 5‐lipoxygenase (2020) (7)
Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells (2020) (7)
A heat stable serum factor upregulates 5-lipoxygenase activity in HL-60 cells, modulation by TNF alpha or GM-CSF. (1993) (6)
On the Metabolism of Prostaglandins E1 and E2 in the Guinea Pig (1972) (6)
Advances in Prostaglandin and Leukotriene Research (2001) (6)
On the Mechanism of the Formation of Hyodeoxycholic Acid in the Pig. Bile Acids and Steroids. 89. (1959) (6)
5-lipoxygenase expression in cultured human keratinocytes. (1995) (6)
Conformational analysis of lipoxin A, lipoxin B and their trans-isomers. (1988) (6)
The human leukocyte 5-lipoxygenase: enzyme purification, multi-component regulatory system, and LTA4 synthase activity. (1986) (6)
On the metabolism of prostaglandin F-2-alpha in female subjects. (1971) (6)
Prostaglandin-F2 alpha receptor in human corpora lutea [letter] (1974) (6)
Lipoxins: stereochemistry, biosynthesis and biological activities. (1986) (6)
Inhibition of adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide PGH2. (1976) (6)
Demonstration of multiple regulatory factors for purified human leukocyte 5-lipoxygenase. (1987) (5)
Phorbol ester upregulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes (2001) (5)
Prostaglandins and related factors No. 16. Prostaglandins in human seminal plasma. (1966) (5)
PROSTAGLANDINS AND RELATED FACTORS. 15. THE STRUCTURES OF PROSTAGLANDIN E1, F1-ALPHA, AND F1-BETA. (1963) (5)
Molecular biology of leukotriene and lipoxin formation. (1989) (5)
Antagonism of the prostaglandin endoperoxide imhibition of hormone-stimulated adenylate cyclase by guanosine triphosphate and 5'-guanylyl-imidodiphosphate. (1976) (5)
Prostaglandin Endoperoxides and Thromboxanes: Short-Lived Bioregulators (1977) (5)
OVERVIEW OF THE 5-LIPOXYGENASE PATHWAY (1998) (5)
Prostanoids and Drugs (1989) (5)
Characterization of the promoter of the human 5-lipoxygenase gene. (1991) (4)
Transcriptional and posttranscriptional regulation of 5-lipoxygenase mRNA expression in the human monocytic cell line Mono Mac 6 by transforming growth factor-beta and 1,25-dihydroxyvitamin D3. (1999) (4)
Effects of prostaglandins E1 and E2 and prostaglandin endoperoxides on the isolated human umbilical artery (1974) (4)
5-lipoxygenase: structure and stability of recombinant enzyme, regulation in Mono Mac 6 cells. (1995) (4)
Radioimmunoassay for thromboxane B/sub 2/. [Prostaglandin endoperoxide metabolite; /sup 14/C] (1976) (4)
Biosynthesis of leukotriene A4 from 5-hydroperoxyeicosatetraenoic acid: possible involvement of 8-lipoxygenase reaction. (1985) (4)
Production and binding of leukotrienes in the rat brain. (1987) (3)
Evidence for leukotriene formation and a neuroendocrine role for leukotriene C4 in rat brain. (1985) (3)
Prostaglandins and related compounds (1987) (3)
The synthesis and biological role of prostaglandins. (1972) (3)
NMR structure of human coactosin-like protein. (2004) (3)
Molecular biology and cloning of archidonate 5-lipoxygenase. (1990) (3)
On the Formation and Biological Role of Leukotrienes and Lipoxins (1987) (3)
Prostaglandins and related factors. Pt. 18. Isolation and identification of prostaglandins from human seminal plasma. (1963) (3)
Prostaglandin Endoperoxides and Thromboxanes: Role in Platelets (1977) (3)
SIMPLE, STEREOCONTROLLED TOTAL SYNTHESIS OF A BIOLOGICALLY ACTIVE ANALOG OF THE PROSTAGLANDIN ENDOPEROXIDES (PGH2, PGG2) (1976) (3)
Leukotriene A4-hydrolase, cloning of the human enzyme and tissue distribution in the rat. (1989) (3)
A Novel Series of Biologically Active Compounds (1985) (2)
Pillars Article: Leukotriene C: A Slow-Reacting Substance from Murine Mastocytoma Cells. Proc. Natl. Acad. Sci. USA. 1979. 76: 4275-4279. (2018) (2)
11th International Conference Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications (1999) (2)
Purification of 15-lipoxygenase from human leukocytes, evidence for the presence of isozymes. (1991) (2)
Purification and properties of leukotriene A4 hydrolase in human leukocytes. (1985) (2)
IDENTIFICATION OF PROSTAGLANDIN F3-ALPHA IN BOVINE LUNG: PROSTAGLANDINS AND RELATED FACTORS 26. (1964) (2)
Prostaglandins: serologic specificities and estimation in biological fluids (1972) (2)
Prostaglandins and related compounds : seventh international conference, Florence, Italy (1991) (2)
The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes (2022) (2)
Neuropeptides and their Possible Role as Auxiliary Messengers (1986) (2)
Effects of metal ions on the binding activity of the human leukocyte leukotriene B4 receptor. (1997) (2)
Leukotriene A 4 Hydrolase: A Zinc Metalloenzyme with Dual Enzymatic Activities (1993) (2)
Formation of novel biologically active leukotrienes by omega-oxidation in human leukocyte preparations. (1982) (2)
Effects of leukotrienes on in vitro neutrophil functions. (1982) (2)
The Leukotrienes: Role in Allergy (1983) (2)
Prostaglandins in fertility control : reports of the third Conference on Prostaglandins in Fertility Control, Jan. 17-20, 1972, Stockholm. Organized at the WHO Research and Training Centre on Human Reproduction (1972) (1)
Macrocyclic inhibitors of the Hepatitis C virus (2006) (1)
Prostaglandins : proceedings of the Second Nobel Symposium, Stockholm, June 1966 (1967) (1)
19-hydroxylated prostaglandins. (1967) (1)
[Leukotrienes: role in allergy and inflammation]. (1991) (1)
Prostaglandin E synthase: A microsomal, glutathione dependent, inducible member of the MAPEG superfamily (1999) (1)
Studies on the active site of leukotriene A4 hydrolase. (1997) (1)
The structure of the main urinary metabolite of prostaglandin F2-alpha in the guinea pig. (1969) (1)
Stereochemical Course of the Conversion of Cholesterol to Bile Acid. (1959) (1)
The structure of a urinary metabolite of prostaglandin F2 alpha in man. [Letter] (1969) (1)
Molecular Biology of Leukotriene Formation (1989) (1)
Letter: Prostaglandin-F2alpha receptor in human corpora lutea. (1974) (1)
Prostaglandin F2α Receptors in Corpora Lutea (1976) (1)
Isolation and Structure of Two Prostaglandin Endoperoxides That Cause (2016) (1)
Leukotrienes as Mediators of Asthma and Inflammation: Basic and Applied Research. Proceedings of an international workshop. Interlaken, Switzerland, September 7-12, 1992. (1995) (1)
873 – TISSUE DIFFERENCES IN THE RELATIVE POTENCY OF PGI2 AND PGE:s: STUDIES ON HUMAN LYMPHOCYTES AND RAT ADIPOCYTES (1978) (1)
Occurrence of Leukotrienes in Rat Brain (1985) (1)
Molecular cloning and amino acid sequence of human 5-lipoxygenase. (1989) (1)
Enzymatic assay of the prostaglandins. (1968) (1)
Prostaglandin F2alpha receptor in ovine corpora lutea. (1974) (1)
Formation of Lithocholic Acid from Ursodeoxycholic Acid in the Rat. Bile Acids and Steroids 116. (1962) (1)
Excretion and nature of bile acids formed from cholic acid-24-14C and deoxycholic acid-24-14C in bile duct ligated rats. (1959) (1)
Biosynthesis of 9-alpha,15-dihydroxy-11-ketoprost-13-enoic acid. (1968) (1)
On the Metabolism of Prostaglandins E , and E , in the Guinea Pig * (2002) (1)
Prostaglandin Endoperoxides and Thromboxanes: Biochemistry and Biological Role (1979) (0)
Trends in eicosanoid biology. (1990) (0)
The Role of Prostaglandins and Thromboxanes in Platelets (1979) (0)
Notice to authors: Eicosanoid nomenclature (1989) (0)
Synthesis of Tritium-labeled Prostaglandin E , and on Its Metabolism in Guinea Pig Lung Studies 37 (2003) (0)
New Prostancarbonsaeurederivate, their preparation and use (1969) (0)
Taipei conference on prostaglandins and leukotriene research (1989) (0)
[Formation and metabolism of prostaglandins]. (1971) (0)
1068 – PROSTAGLANDIN ENDOPEROXIDES AND THROMBOXANES: BIOCHEMISTRY AND BIOLOGICAL ROLE (1978) (0)
Derives de nucleoside (1991) (0)
Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases (2001) (0)
New Drugs: The Role of Basic Science (1999) (0)
SELEKTIVE INHIBITION VON PROSTAGLANDIN-SYNTHETASE DURCH EIN BICYCLO(2,2,1)HEPTEN-DERIVAT (1971) (0)
Studies in the Mechanism of Bile Acid Formation. (1957) (0)
1068 – PROSTAGLANDIN ENDOPEROXIDES AND THROMBOXANES: BIOCHEMISTRY AND BIOLOGICAL ROLE (1978) (0)
Mutations of the Three Zinc-Ligands of Leukotriene A4 Hydrolase: Effects on Zinc Content and Enzyme Activities (1993) (0)
The synthesis and biological role of prostaglandins. (1972) (0)
Abstract A49: Inhibition of adriamycin‐induced 5‐lipoxygenase in DU‐145 and PC3 prostate cancer cells confers cell death (2009) (0)
STEREOSPECIFIC TOTAL SYNTHESIS OF A “SLOW REACTING SUBSTANCE” OF ANAPHYLAXIS, LEUKOTRIENE C-1 (1980) (0)
1137 – THE R0LE 0F PROSTAGLANDIN ENDOPEROXIDES IN HUMAN PLATELETS (1977) (0)
Metabolism of Arachidonic Acid by 12- and 15-Lipoxygenases in Human Platelets and Polymorphonuclear Leukocytes (1985) (0)
Solubilization of a prostaglandin F2alpha receptor in bovine corpora lutea. (1975) (0)
Intermediates for the preparation of macrocyclic hepatitis C virus inhibitors (2006) (0)
Characterization of the human 5-lipoxygenase gene. (1989) (0)
A process for the preparation of S-metoprolol and its intermediates. (1989) (0)
LEUCOTRIENES, SUPERACTIVE ON ALLERGY AND INFLAMMATION-CAUSING HORMONES (1983) (0)
Prostaglandin Endoperoxides. A NewConcept Concerning theMode ofAction andRelease ofProstaglandins* (platelet aggregation/prostaglandin Gi/endoperoxide metabolites/quantitative determination/ aspirin andindomethacin) (1974) (0)
The prostaglandins. (1968) (0)
" Isolation and structural characterization of a cDNA clone encoding rat gastric intrinsic factor , " by (2003) (0)
Mats Hamberg and Bengt Samuelsson in the Guinea Pig 2 and E 1 On the Metabolism of Prostaglandins E (2002) (0)
Oxidative products of arachidonate: leukotrienes, a new group of compounds, including slow-reacting substance of anaphylaxis (SRA-A). (1981) (0)
Characterization of the human 5-lipoxygenase gene ( DNA sequence / intron / exon junctions / promoter / protein domains ) (0)
Leukotriene A 4 : mechanism of formation and enzymatic hydrolysis (1984) (0)
Novel Inhibitors of Leukotrienes (Series: Progress in Inflammation Research (edited by Michael J. Parnham)) (2000) (0)
Bengt Samuelsson FORMATION OF DEOXYCHOLIC ACID FROM CHOLIC ACID Bile Acids and Steroids : 96 (2003) (0)
Composition for the treatment of proliferative skin diseases (1978) (0)
The biosynthesis of prostaglandin-E1 studied with specifically 3H-labeled precursors. (1966) (0)
Prostaglandins and thromboxanes : [lectures] (1977) (0)
5-Lipoxygenase and Coactosin-like protein ; Leukotriene production by exosomes (2010) (0)
Erratum (1976) (0)
Studies on Expression and Regulation of 5-Lipoxygenase in Human B Lymphocytes (1993) (0)
Leukotrienes in the rat central nervous system ( brain tissue / arachidonic acid metabolism / lipoxygenase pathway / leukotriene synthesis distribution / leukotriene C 4 immunoreactivity ) (0)
Sune Bergström , Sven Lindstedt and Bengt Samuelsson DEOXYCHOLIC ACID FORMATION IN THE RABBIT Bile Acids and Steroids : LXXXII (2003) (0)
Metabolism of prostaglandin F2$alpha$ in female subjects (1972) (0)
Prostaglandin F2 alpha receptors in corpora lutea. (1976) (0)
COMMENTARY (2007) (0)
On the Metabolism of Prostaglandin Fza in Female Subjects* (2002) (0)
5-Lipoxygenase: mechanisms of regulation 1 (2009) (0)
Cloning of leukotriene A4 hydrolase cDNA. (1990) (0)
Third conference on prostaglandins in fertility control, Stockholm, Sweden, January 17--20, 1972 (1972) (0)
Bengt Samuelsson 18 . PROSTAGLANDINS AND RELATED FACTORS Isolation and Identification of Prostaglandins from Human Seminal Plasma (2003) (0)
Guidelines for the nomenclature of: A. Leukotrienes and related hydroxy, hydroperoxy, epoxy, and oxo-fatty acids B. Enzymes involved in eicosanoid metabolism (1989) (0)
Biosynthesis and metabolism of leukotriene A4 (1984) (0)
Prostaglandin E2 and Sphingosine-1-phosphate induced dicer upregulation and miRNAs formations in anti-inflammatory macrophages (2018) (0)
Detection andIsolation ofanEndoperoxide Intermediate in Prostaglandin Biosynthesis (fatty acidoxygenase/endoperoxide isomerase/endoperoxide reductase/rabbit aorta-contracting substance) (1973) (0)
Enhancement of the sensitivity of hamster cheek pouch arterioles to beta-adrenergic stimulus during pregnancy (1982) (0)
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase (2023) (0)
macrocyclic compounds as inhibitors of hepatitis C virus (2006) (0)
Dicer upregulation in differentiating monocytic cells by inhibition of specific proteolysis (2018) (0)
1336 – PROSTAGLANDIN ENDOPEROXIDES AND THROMBOXANES: ROLE IN PLATELETS (1978) (0)
Moncada S, Gryglewski R, Bunting S & Vane J R. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263:663-5, 1976 (2004) (0)
Complex of human leukotriene A4 hydrolase with a hydroxamic acid inhibitor (2008) (0)
Decreased rate of metabolism induced by a shift of the double bond in prostaglandin F 2alpha from the delta5 to the delta4 position. (1976) (0)
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT (2003) (0)

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