Barbara Low
American biochemist and biophysicist
Barbara Low 's AcademicInfluence.com Rankings


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Physics Biology
Barbara Low 's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Barbara Low Influential?
(Suggest an Edit or Addition)According to Wikipedia, Barbara Wharton Low was a biochemist, biophysicist, and a researcher involved in discovering the structure of penicillin and the characteristics of other antibiotics. Her early work at Oxford University with Dorothy Hodgkin used X-ray crystallography to confirm the molecular structure of penicillin, which at the time was the largest molecule whose structure has been determined using that method. Later graduate work saw her study with Linus Pauling and Edwin Cohn before becoming a professor in her own right. Low's laboratory would accomplish the discovery of the pi helix, investigate the structure of insulin, and conduct research into neurotoxins.
Barbara Low 's Published Works
Published Works
- Three dimensional structure of erabutoxin b neurotoxic protein: inhibitor of acetylcholine receptor. (1976) (210)
- The Use of the Gradient Tube for the Determination of Crystal Densities1a (1952) (140)
- The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core. (1980) (140)
- Refinement at 1.4 A resolution of a model of erabutoxin b: treatment of ordered solvent and discrete disorder. (1988) (79)
- Molecular conformation of erabutoxin b; atomic coordinates at 2.5 A resolution. (1979) (78)
- THE π HELIX—A HYDROGEN BONDED CONFIGURATION OF THE POLYPEPTIDE CHAIN (1952) (66)
- Generalized Mathematical Relationships for Polypeptide Chain Helices: The Coordinates of the II Helix. (1953) (65)
- The Three-Dimensional Structure of Postsynaptic Snake Neurotoxins: Consideration of Structure and Function (1979) (54)
- Measurements of the Density, Composition and Related Unit Cell Dimensions of Some Protein Crystals1a (1954) (53)
- The crystal structure of erabutoxin a at 2.0-A resolution. (1990) (50)
- STUDIES OF INSULIN CRYSTALS AT LOW TEMPERATURES: EFFECTS ON MOSAIC CHARACTER AND RADIATION SENSITIVITY* (1966) (49)
- Erabutoxin b. Initial protein refinement and sequence analysis at 0.140-nm resolution. (1985) (48)
- Glycinate Complexes of Zinc and Cadmium (1959) (48)
- Erabutoxin b. Structure/function relationships following initial protein refinement at 0.140-nm resolution. (1986) (47)
- An x-ray crystallographic study of ceruloplasmin. Determination of molecular weight. (1969) (47)
- Preparation and Properties of Serum and Plasma Proteins. XXXIV. An X-Ray Study of Crystalline Human Serum Albumin Preparations1a, 1b (1952) (40)
- Drug‐induced Autoimmune Myasthenia Gravis a (1998) (40)
- Proinsulin: Crystallization and preliminary x-ray diffraction studies. (1970) (31)
- Crystal Structure of the C-Terminal Tetrapeptide of Oxytocin (1971) (24)
- α‐Toxin binding to acetylcholine receptor α179–191 peptides: Intrinsic fluorescence studies (1988) (23)
- Early papers on diffraction of X-rays by crystals (1969) (22)
- X-ray crystallographic study of the erabutoxins and of a diiodo derivative. (1971) (21)
- Determination of Protein Crystal Densities (1952) (20)
- The structure of the 2:1 complex between the bile acid deoxycholic acid and (+)-camphor (1982) (20)
- Crystal structure and hydrogen-bonding system of cholic acid hemihydrate, C24H40O5·1/2H2O (1993) (18)
- Precipitation and crystallization of insulin in the presence of lysozyme and salmine. (1970) (18)
- Orientation of the Polypeptide Chains in Crystals of Acid Insulin Sulphate (1952) (18)
- Insulin. Some shrinkage stages of sulfate and citrate crystals (1962) (17)
- Some Studies of Protein Crystals in a Variety of Different Media1 (1956) (17)
- The crystal structure of S‐benzyl‐l‐cysteinyl‐l‐prolyl‐l‐leucylglycinamide and its selenium analog (1975) (16)
- The Packing Structure of Crystalline RI-APC Virus (1956) (16)
- Symmetry of Insulin Dimers and Hexamers (1960) (15)
- Insulin/proinsulin, a new crystalline complex (1974) (13)
- Conformational requirements of acetylcholine analogues and local anaesthetics. (1972) (11)
- Prediction of alpha-helical regions in proteins of known sequence. (1968) (10)
- Insulin: preliminary X-ray studies of citrate crystals (1961) (10)
- Predictions of backbone conformational changes in abnormal haemolgobins. (1972) (9)
- Preparation and Properties of Serum and Plasma Proteins. XXXI. An Optical and Morphological Study of Some Crystalline Human Serum Albumin Preparations and of Their Derivatives1a,1b (1951) (9)
- Insulin crystallization in the presence of basic proteins and peptides. (1970) (8)
- Proinsulin: further crystallization and x-ray crystallographic studies of bovine and porcine prohormone. (1972) (8)
- INSULIN-A PROBABLE GROSS MOLECULAR STRUCTURE. (1963) (7)
- Monoclinic insulin crystals. (1969) (7)
- Insulin ... Preliminary X-ray Studies of Two Types of Sulphate Crystals (1959) (6)
- Insulin: preliminary x-ray studies of chloride crystals and a crystalline derivative. (1965) (6)
- INSULIN-GROSS MOLECULAR STRUCTURE: TRIAL-AND-ERROR STUDIES USING TRANSFORM AND PATTERSON FUNCTION TECHNIQUES. (1962) (5)
- Deamino Oxytocin and 1-γ-Mercaptobutyric Acid-Oxytocin: X-ray Crystallographic Data (1966) (5)
- Preliminary X‐ray crystallographic data for methyl 3‐O‐(1‐carboxyethyl) shikimate δ‐lactone (1966) (5)
- Crystalline erabutoxin c. (1975) (4)
- The three‐dimensional Patterson function for insulin sulfate type A crystals (1961) (4)
- Preliminary x-ray crystallographic study of porcine transferrin. (1970) (4)
- X-ray crystallographic study of laticotoxin a. (1973) (4)
- The crystal structures of glycyl-l-phenylalanine p-toluenesulfonate and glycyl-L-phenylalanine p-bromobenzenesulfonate (1972) (3)
- Structural Chemistry and Molecular Biology. A Volume Dedicated to Linus Pauling. Alexander Rich and Norman Davidson, Eds. Freeman, San Francisco, 1968. xii + 907 pp., illus. $10 (1968) (3)
- Experimental Data and Model Structures for the Insulin Molecule (1953) (3)
- Reply to "Prediction of a-Helices in Glucagon" by Schiffer and Edmundson (1971) (2)
- Structure of a potent neuromuscular blocking agent: Caracurine-II dimethochloride octahydrate, [C40H44N4O2]2+·2CI−·8H2O (1985) (2)
- A simple device for optical superposition of skeletal atomic models and electron density maps (1970) (2)
- Prolactin synthesis in primates. (1971) (2)
- Parallel Light Device for `Trial and Error' Fourier Analysis (1949) (2)
- Crystalline salts of oxytocin: X-ray crystallographic data (1971) (2)
- Alpha-toxin binding to acetylcholine receptor alpha 179-191 peptides: intrinsic fluorescence studies. (1988) (2)
- Deamino-oxytocin and 1-gamma-mercaptobutyric acid-oxytocin: x-ray crystallographic data. (1966) (1)
- The use of x-ray diffraction in the determination of protein structure (1961) (1)
- Symposia of the Society for Experimental Biology. Number IX. Fibrous Proteins and their Biological Significance (1956) (1)
- Neurotoxin Binding Site on the Acetylcholine Receptor: Stereochemical Model and Proposed Mechanism of Binding (1987) (1)
- Three-dimensional structure of erabutoxin b, prototype structure of the snake venom postsynaptic neurotoxins: consideration of structure and function; description of the reactive site. (1979) (1)
- PREDICTION OF a-HELICAL REGIONS IN PROTEINS OF KNOWN SEQUENCE* (1)
- A Note on the Crystallography of Helvolic Acid and the Methyl Ester of Helvolic Acid. (1943) (1)
- Proceedings: Structure studies of a sea snake neurotoxin "erabutoxin b". (1976) (1)
- Crystalline insulin-ribonuclease. The presence of large molecular aggregates. (1971) (0)
- Some Considerations of Structure and Function in Proteins (1960) (0)
- Search for solutions (1982) (0)
- EFFECTS ON MOSAIC CHARACTER AND RADIATION SENSITIVITY (2016) (0)
- John T. Edsall: his key role in the determination of the structure of proteins. (2002) (0)
- X-RAY STRUCTURE OF ERABUTOXIN C, A DIMERIC NEUROTOXIN (2019) (0)
- Caracurine-II dimethochloride octahydrate, a potent neuromuscular blocking agent (1984) (0)
- Studies of insulin crystals at low temperatures. Effects on lattice dimensions, temperature parameters and structure (1970) (0)
- The Structure Of Erabutoxin C At 2.1A Resolution (2019) (0)
- The structure of erabutoxin B at 1.4 Å resolution. Structure/function relations including functional implications of the extensive water structure and side-chain disorder in the reactive site (1984) (0)
- Crystal structures. Section III and supplement II. RALPH W. G. WYCKOFF. Interscience, New York‐London, 1953. Section III: 244 text pp., 176 illus., 220 table pp., $10.00. Supplement II: 30 text pp., 64 table pp., $4.00 (1953) (0)
- STRUCTURE-FUNCTION RELATIONSHIPS IN POSTSYNAPTIC SNAKE NEUROTOXINS (1980) (0)
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