Beat Fierz
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Physics
Beat Fierz's Degrees
- PhD Physics ETH Zurich
- Masters Physics University of Zurich
- Bachelors Physics University of Zurich
Why Is Beat Fierz Influential?
(Suggest an Edit or Addition)According to Wikipedia, Beat Fierz is a Swiss chemist and molecular biologist, currently an Associate Professor at the EPFL . His research is focused on understanding dynamic processes of large molecular systems, particularly in chromatin regulation.
Beat Fierz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Histone H2B ubiquitylation disrupts local and higher order chromatin compaction (2010) (406)
- Dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding. (2003) (217)
- Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation. (2010) (210)
- Accelerated Chromatin Biochemistry Using DNA-Barcoded Nucleosome Libraries (2014) (127)
- Chromatin as an expansive canvas for chemical biology. (2012) (113)
- Structural mechanism of cGAS inhibition by the nucleosome (2020) (112)
- DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation (2017) (90)
- Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α (2018) (90)
- Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis. (2012) (83)
- A two-state activation mechanism controls the histone methyltransferase Suv39h1 (2016) (81)
- BAF restricts cGAS on nuclear DNA to prevent innate immune activation (2020) (78)
- Multivalency governs HP1α association dynamics with the silent chromatin state (2015) (76)
- Biophysics of Chromatin Dynamics. (2019) (72)
- Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale (2007) (72)
- Local conformational dynamics in α-helices measured by fast triplet transfer (2009) (64)
- Sumoylated Human Histone H4 Prevents Chromatin Compaction by Inhibiting Long-range Internucleosomal Interactions* (2014) (62)
- End-to-end vs interior loop formation kinetics in unfolded polypeptide chains. (2007) (62)
- Histone H3K27 Trimethylation Inhibits H3 Binding and Function of SET1-Like H3K4 Methyltransferase Complexes (2013) (52)
- Dynamic chromatin technologies: from individual molecules to epigenomic regulation in cells (2017) (52)
- Ultrafast Quenching of the Xanthone Triplet by Energy Transfer: New Insight into the Intersystem Crossing Kinetics (2004) (48)
- Chromatin Fiber Invasion and Nucleosome Displacement by the Rap1 Transcription Factor (2019) (47)
- “Doubly Orthogonal” Labeling of Peptides and Proteins (2019) (45)
- Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions (2017) (42)
- Traceless Synthesis of Asymmetrically Modified Bivalent Nucleosomes. (2016) (41)
- Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation (2019) (40)
- On the unusual fluorescence properties of xanthone in water. (2006) (39)
- Histone Monoubiquitylation Position Determines Specificity and Direction of Enzymatic Cross-talk with Histone Methyltransferases Dot1L and PRC2* (2012) (35)
- Engineered Multivalent Sensors to Detect Coexisting Histone Modifications in Living Stem Cells. (2017) (27)
- Intrachain diffusion in a protein loop fragment from carp parvalbumin (2004) (27)
- Testing the diffusing boundary model for the helix–coil transition in peptides (2013) (24)
- Engineering chromatin states: chemical and synthetic biology approaches to investigate histone modification function. (2014) (18)
- Dynamics of Unfolded Polypeptide Chains (2005) (16)
- Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein (2022) (16)
- A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00681d (2018) (15)
- KAP1 is an antiparallel dimer with a functional asymmetry (2019) (13)
- Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1 (2020) (13)
- Using triplet-triplet energy transfer to measure conformational dynamics in polypeptide chains. (2007) (12)
- The elusive structure of centro-chromatin: molecular order or dynamic heterogenetity? (2020) (11)
- Synthetic Chromatin Approaches To Probe the Writing and Erasing of Histone Modifications (2014) (11)
- Dynamic Chromatin Regulation from a Single Molecule Perspective. (2016) (9)
- SUV39 SET domains mediate crosstalk of heterochromatic histone marks (2020) (9)
- PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction (2022) (9)
- Disordered Proteins Enable Histone Chaperoning on the Nucleosome (2020) (9)
- A Modular Ligation Strategy for Asymmetric Bivalent Nucleosomes Trimethylated at K36 and K27 (2019) (7)
- Multivalent Peptide Ligands To Probe the Chromocenter Microenvironment in Living Cells. (2022) (6)
- Controlling the supramolecular assembly of nucleosomes asymmetrically modified on H4. (2017) (6)
- O-GlcNAcylation of High Mobility Group Box 1 (HMGB1) Alters Its DNA Binding and DNA Damage Processing Activities. (2021) (6)
- Re-evaluating the role of nucleosomal bivalency in early development (2021) (5)
- Chemical and biophysical methods to explore dynamic mechanisms of chromatin silencing. (2019) (5)
- KAP1 is an antiparallel dimer with a natively functional asymmetry (2019) (4)
- De novo design of site-specific protein interactions with learned surface fingerprints (2023) (3)
- Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor (2021) (3)
- The mechanistic basis for chromatin invasion and remodeling by the yeast pioneer transcription factor Rap1 (2019) (3)
- Nucleosome binding by the lysine specific demethylase 1 (LSD1) enzyme enables histone H3 demethylation. (2020) (3)
- Revealing chromatin organization in metaphase chromosomes (2019) (2)
- Observing protein interaction dynamics to chemically defined chromatin fibers by colocalization single-molecule fluorescence microscopy. (2020) (2)
- Chromatin as a Dynamic Platform for Protein-Protein Interactions (2014) (1)
- De novo design of protein interactions with learned surface fingerprints (2023) (1)
- Single-molecule dynamics and genome-wide transcriptomics reveal that NF-κB (p65)-DNA binding times can be decoupled from transcriptional activation (2018) (1)
- Slow fluorescence and fast intersystem crossing - The xanthone anomaly (2006) (1)
- Dynamics of unfolded and [alpha]-helical polypeptide chains (2007) (1)
- CENP-A and CENP-B collaborate to create an open centromeric chromatin state (2022) (1)
- Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α-Fig. 7cde (2017) (1)
- Revealing chromatin state organization on the single‐molecule scale (2018) (0)
- Heterochromatin Assembly and Dynamics on the Single Molecule Level (2015) (0)
- 5 Conformational dynamics in peptides and proteins studied by triplet-triplet energy transfer (2011) (0)
- Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α (2018) (0)
- Applying Peptide and Protein Synthesis to Study Post-translational Modifications in Epigenetics and Beyond. (2021) (0)
- Multivalent peptide ligands to probe the chromocenter microenvironment in living cells (2021) (0)
- Structural mechanism of cGAS inhibition by the nucleosome (2020) (0)
- Semisynthesis and Reconstitution of Nucleosomes Carrying Asymmetric Histone Modifications. (2020) (0)
- Front Cover: A Modular Ligation Strategy for Asymmetric Bivalent Nucleosomes Trimethylated at K36 and K27 (ChemBioChem 9/2019) (2019) (0)
- Chromatin Remodeling Induced by the Invasion of Yeast Pioneer Transcription Factor Rap1 Revealed by Single-Molecule FRET (2019) (0)
- Multiplexed single-molecule experiments reveal Cas9 nucleosome invasion dynamics (2022) (0)
- Target Search Dynamics of Sox Transcription Factors (2022) (0)
- 2016 International Symposium on Chemical Biology of the NCCR Chemical Biology Campus Biotech, Geneva 13-15.1.2016. (2016) (0)
- Target search dynamics of Sox transcription factors. (2023) (0)
- Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination (2022) (0)
- Reconstitution of heterochromatin spreading on designer chromatin reveals a two-state activation mechanism for the histone methyltransferase Suv39h1 (2015) (0)
- Molecular and Chemical Mechanism in Epigenetics - Swiss Summer School 2015 July 12-17, 2015, Hotel Kurhaus, Arolla, Switzerland. (2015) (0)
- Discrete Mechanisms Govern the Modulation of Chromatin Structure by Ubiquitylation and Acetylation (2011) (0)
- Gene control with a "twist": Exploring the dynamic chromatin landscape Gene control with a "twist": Exploring the dynamic chromatin landscape (2019) (0)
- Development of a single-molecule approach to observe ubiquitination dynamics in defined chromatin states (2022) (0)
- Medicinal Chemistry and Chemical Biology Highlights (2022) (0)
- Phase Separation as an Emergent Concept in Genome Organization and Beyond (2022) (0)
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What Schools Are Affiliated With Beat Fierz?
Beat Fierz is affiliated with the following schools:
