Ben G. Davis

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Ben G. Davis is affiliated with the following schools: University of Oxford, University of Toronto, Harvard University

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Ben G. Davis

Chemistry

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Chemistry

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According to Wikipedia, Benjamin Guy Davis is Professor of Chemical biology in the Department of Pharmacology and a member of the Faculty in the Department of Chemistry at the University of Oxford and a Fellow of Pembroke College, Oxford. He holds the role of Science Director for Next Generation Chemistry and Deputy and Interim Director at the Rosalind Franklin Institute.

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Ben G. Davis's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation (2010) (1129)
Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. (2001) (704)
Selective chemical protein modification (2014) (650)
Glycoprotein synthesis: an update. (2009) (444)
Chemical modification of proteins at cysteine: opportunities in chemistry and biology. (2009) (436)
Functional Divergence in the Glutathione Transferase Superfamily in Plants (2002) (410)
Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification (2006) (389)
Lectins: tools for the molecular understanding of the glycocode. (2005) (375)
Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation (2014) (368)
Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial. (2000) (368)
Synthesis of glycoproteins. (2002) (368)
Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. (2005) (339)
A "tag-and-modify" approach to site-selective protein modification. (2011) (271)
Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins. (2008) (267)
Expanding the diversity of chemical protein modification allows post-translational mimicry (2007) (263)
Allyl sulfides are privileged substrates in aqueous cross-metathesis: application to site-selective protein modification. (2008) (261)
Methods for converting cysteine to dehydroalanine on peptides and proteins (2011) (255)
Filled and glycosylated carbon nanotubes for in vivo radioemitter localization and imaging. (2010) (251)
A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling. (2009) (250)
Glyconanoparticles allow pre-symptomatic in vivo imaging of brain disease (2009) (220)
Recent developments in oligosaccharide synthesis (2000) (215)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity (2016) (192)
Palladium-mediated cell-surface labeling. (2012) (185)
Thiyl glycosylation of olefinic proteins: S-linked glycoconjugate synthesis. (2009) (184)
‘Multicopy Multivalent’ Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines (2013) (182)
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis. (2011) (166)
Biocatalysis and enzymes in organic synthesis. (2001) (161)
Sugar synthesis in a protocellular model leads to a cell signalling response in bacteria. (2009) (161)
Conversion of cysteine into dehydroalanine enables access to synthetic histones bearing diverse post-translational modifications. (2012) (153)
Chemical modification of biocatalysts. (2003) (150)
Olefin cross-metathesis on proteins: investigation of allylic chalcogen effects and guiding principles in metathesis partner selection. (2010) (149)
Hydrogen bonding and cooperativity in isolated and hydrated sugars: mannose, galactose, glucose, and lactose. (2005) (141)
QuaNCAT: quantitating proteome dynamics in primary cells (2013) (140)
Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution. (2003) (139)
Exploring and exploiting the therapeutic potential of glycoconjugates. (2006) (137)
Glyco-SeS: selenenylsulfide-mediated protein glycoconjugation--a new strategy in post-translational modification. (2004) (134)
Inhibition of SnRK1 by metabolites: tissue-dependent effects and cooperative inhibition by glucose 1-phosphate in combination with trehalose 6-phosphate. (2013) (134)
Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase. (2011) (134)
The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity (2007) (132)
Olefin Metathesis for Site‐Selective Protein Modification (2009) (132)
Chemical intervention in plant sugar signalling increases yield and resilience (2016) (128)
High-purity discrete PEG-oligomer crystals allow structural insight. (2009) (126)
Sensing the anomeric effect in a solvent-free environment (2011) (125)
Fully Differentiated HIV-1 Specific CD8+ T Effector Cells Are More Frequently Detectable in Controlled than in Progressive HIV-1 Infection (2007) (122)
Removal of amorphous carbon for the efficient sidewall functionalisation of single-walled carbon nanotubes. (2007) (119)
Recent developments in glycoconjugates (2000) (119)
Ocular syphilis among HIV-infected patients: a systematic analysis of the literature (2010) (117)
An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling. (2012) (112)
Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection (2012) (111)
Drug delivery systems based on sugar-macromolecule conjugates. (2002) (105)
An autonomous molecular assembler for programmable chemical synthesis. (2016) (104)
The direct formation of glycosyl thiols from reducing sugars allows one-pot protein glycoconjugation. (2006) (103)
The building blocks of cellulose: the intrinsic conformational structures of cellobiose, its epimer, lactose, and their singly hydrated complexes. (2009) (102)
Systemic Inflammatory Response Reactivates Immune-Mediated Lesions in Rat Brain (2009) (99)
DNA Modification under Mild Conditions by Suzuki–Miyaura Cross-Coupling for the Generation of Functional Probes** (2013) (99)
Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection (2006) (97)
Palladium-mediated site-selective Suzuki-Miyaura protein modification at genetically encoded aryl halides. (2011) (96)
From disulfide- to thioether-linked glycoproteins. (2008) (96)
The imitation game—a computational chemical approach to recognizing life (2006) (94)
Mimicking Posttranslational Modifications of Proteins (2004) (94)
Self-liganded Suzuki-Miyaura coupling for site-selective protein PEGylation. (2013) (92)
Chemical modification in the creation of novel biocatalysts. (2011) (92)
A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity (2010) (90)
Rapid Cross-Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl-selenocysteine in Proteins (2013) (90)
Multi-molecule reaction of serum albumin can occur through thiol-yne coupling. (2011) (89)
Enhanced Aqueous Suzuki–Miyaura Coupling Allows Site-Specific Polypeptide 18F-Labeling (2013) (85)
Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors. (2010) (82)
Longitudinal analysis of clinical markers following antiretroviral therapy initiated during acute or early HIV type 1 infection. (2006) (80)
Can Carbon Nanotubes Deliver on Their Promise in Biology? Harnessing Unique Properties for Unparalleled Applications (2016) (79)
Structural dissection and high-throughput screening of mannosylglycerate synthase (2005) (79)
IR-spectral signatures of aromatic-sugar complexes: probing carbohydrate-protein interactions. (2007) (78)
LEAPT: lectin-directed enzyme-activated prodrug therapy. (2004) (75)
Realizing the Promise of Chemical Glycobiology. (2013) (75)
Glycomethanethiosulfonates: powerful reagents for protein glycosylation (2000) (75)
Investigation of the interaction between peanut agglutinin and synthetic glycopolymeric multivalent ligands. (2005) (74)
Glycodendriproteins: a synthetic glycoprotein mimic enzyme with branched sugar-display potently inhibits bacterial aggregation. (2004) (74)
A silver-lined anniversary of Fleet iminosugars: 1984–2009, from DIM to DRAM to LABNAc (2009) (73)
Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency. (2005) (72)
Optimal Synthetic Glycosylation of a Therapeutic Antibody (2016) (72)
The allylic chalcogen effect in olefin metathesis (2010) (71)
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease (2019) (70)
Site-selective glycosylation of proteins: creating synthetic glycoproteins (2007) (70)
Glyco- and peptidomimetics from three-component Joullié-Ugi coupling show selective antiviral activity. (2005) (69)
Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine. (2009) (69)
Glycosyl disulfides: novel glycosylating reagents with flexible aglycon alteration. (2005) (68)
Selective Metal-Site-Guided Arylation of Proteins. (2016) (67)
Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates. (2012) (67)
Carbohydrate-derived amino-alcohol ligands for asymmetric alkynylation of aldehydes. (2006) (67)
Highly diastereoselective additions to polyhydroxylated pyrrolidine cyclic imines: ready elaboration of aza-sugar scaffolds to create diverse carbohydrate-processing enzyme probes. (2003) (67)
Controlled Site-Selective Glycosylation of Proteins by a Combined Site-Directed Mutagenesis and Chemical Modification Approach (1998) (66)
Selective Radical Trifluoromethylation of Native Residues in Proteins (2018) (66)
Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization (2003) (65)
18F-Trifluoromethylation of Unmodified Peptides with 5-18F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate. (2018) (64)
Synthesis of modified proteins via functionalization of dehydroalanine. (2018) (63)
Rewriting the bacterial glycocalyx via Suzuki-Miyaura cross-coupling. (2013) (63)
A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates. (2011) (62)
Controlled polymer synthesis--from biomimicry towards synthetic biology. (2010) (62)
Carbohydrate molecular recognition: a spectroscopic investigation of carbohydrate-aromatic interactions. (2007) (61)
Free fructose is conformationally locked. (2013) (61)
A carbohydrate-antioxidant hybrid polymer reduces oxidative damage in spermatozoa and enhances fertility (2005) (60)
Glycosyl phenylthiosulfonates (glyco-PTS): novel reagents for glycoprotein synthesis. (2003) (60)
A glycosynthase catalyst for the synthesis of flavonoid glycosides. (2007) (59)
Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases (2010) (59)
Potent Fluoro‐oligosaccharide Probes of Adhesion in Toxoplasmosis (2009) (58)
Selective electrochemical glycosylation by reactivity tuning. (2004) (58)
Atomic-scale detection of organic molecules coupled to single-walled carbon nanotubes. (2007) (56)
Site-selective chemical protein glycosylation protects from autolysis and proteolytic degradation. (2009) (55)
BK virus-associated hemorrhagic cystitis in a Human Immunodeficiency Virus-infected patient. (2002) (54)
Lectins: Tools for the Molecular Understanding of the Glycocode (2005) (54)
Functional and informatics analysis enables glycosyltransferase activity prediction (2018) (54)
Novel cyclic sugar imines: carbohydrate mimics and easily elaborated scaffolds for aza-sugars. (2002) (53)
High‐Throughput Mass‐Spectrometry Monitoring for Multisubstrate Enzymes: Determining the Kinetic Parameters and Catalytic Activities of Glycosyltransferases (2005) (53)
Dissecting tunicamycin biosynthesis by genome mining: cloning and heterologous expression of a minimal gene cluster (2010) (51)
Selenenylsulfide-linked homogeneous glycopeptides and glycoproteins: synthesis of human "hepatic Se metabolite A". (2012) (51)
Core-shell PbI2@WS2 inorganic nanotubes from capillary wetting. (2009) (50)
Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. (2012) (50)
Effects of testosterone administration in human immunodeficiency virus-infected women with low weight: a randomized placebo-controlled study. (2004) (50)
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis (2014) (48)
Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins. (2010) (48)
L-(+)-swainsonine and other pyrrolidine inhibitors of naringinase: Through an enzymic looking glass from D-mannosidase to L-rhamnosidase? (1996) (47)
Group epitope mapping considering relaxation of the ligand (GEM-CRL): including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments. (2010) (47)
Nitrogen inversion as a diastereomeric relay in azasugar synthesis: the first synthesis of adenophorine. (2003) (46)
Concepts of Catalysis in Site-Selective Protein Modifications (2019) (46)
Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins. (2007) (45)
A simple method for the quantitative analysis of resin bound thiol groups (2001) (45)
Chemical mutagenesis: selective post-expression interconversion of protein amino acid residues. (2010) (45)
Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation (2015) (44)
Synthetic post-translational modification of histones. (2018) (44)
Carbohydrate-derived aminoalcohol ligands for asymmetric Reformatsky reactions (2005) (43)
The Three Mycobacterium tuberculosis Antigen 85 Isoforms Have Unique Substrates and Activities Determined by Non-active Site Regions* (2014) (43)
Carbohydrate–aromatic interactions: A computational and IR spectroscopic investigation of the complex, methyl α-l-fucopyranoside · toluene, isolated in the gas phase (2009) (42)
Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity (2014) (42)
Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design (2018) (42)
Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI (2017) (42)
Chemical approaches to mapping the function of post‐translational modifications (2008) (42)
Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii (2009) (42)
Ocular syphilis among HIV-infected individuals. (2010) (41)
An antibacterial vaccination strategy based on a glycoconjugate containing the core lipopolysaccharide tetrasaccharide Hep2Kdo2. (2016) (41)
Glycosyldisulfides: a new class of solution and solid phase glycosyl donors (2001) (41)
Single-molecule interrogation of a bacterial sugar transporter allows the discovery of an extracellular inhibitor. (2013) (41)
Light-driven post-translational installation of reactive protein side chains (2020) (40)
Peptide templated glycosylation reactions (2000) (40)
Tetrazoles of manno- and rhamno-pyranoses: Contrasting inhibition of mannosidases by [4.3.0] but of rhamnosidase by [3.3.0] bicyclic tetrazoles (1999) (40)
Optimal Synthetic Glycosylation of a Therapeutic Antibody (2016) (39)
Conformational choice and selectivity in singly and multiply hydrated monosaccharides in the gas phase. (2008) (39)
Direct deprotected glycosyl-asparagine ligation. (2006) (38)
Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development (2011) (37)
Carbon nanotubes allow capture of krypton, barium and lead for multichannel biological X-ray fluorescence imaging (2016) (37)
Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. (2005) (37)
Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference. (2011) (36)
TETRAZOLES OF MANNO- AND RHAMNO- FURANOSES (1999) (36)
Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores. (2011) (36)
Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation. (2014) (36)
Hydration of sugars in the gas phase: regioselectivity and conformational choice in N-acetyl glucosamine and glucose. (2009) (36)
5-epi-Deoxyrhamnojirimycin is a potent inhibitor of an α-l-rhamnosidase: 5-epi-deoxymannojirimycin is not a potent inhibitor of an α-d-mannosidase (1998) (35)
Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars. (2011) (34)
Reversible dementia in a patient with central nervous system escape of human immunodeficiency virus. (2011) (34)
Glycoprotein Synthesis: An Update (2009) (34)
Unique regulation of the active site of the serine esterase S-formylglutathione hydrolase. (2006) (34)
Most Human Proteins Made in Both Nucleus and Cytoplasm Turn Over within Minutes (2014) (34)
Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis (2018) (33)
Spectral signatures and structural motifs in isolated and hydrated monosaccharides: phenyl α- and β-L-fucopyranoside (2006) (33)
Tailoring the substrate specificity of the β‐glycosidase from the thermophilic archaeon Sulfolobus solfataricus (2001) (33)
Sugars and proteins: New strategies in synthetic biology (2009) (33)
18F-Trifluoromethanesulfinate Enables Direct C–H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides (2020) (32)
From Chemical Mutagenesis to Post‐Expression Mutagenesis: A 50 Year Odyssey (2016) (32)
Conformational change and selectivity in explicitly hydrated carbohydrates (2009) (32)
TETRAZOLES OF MANNO- AND RHAMNO-PYRANOSES : INHIBITION OF GLYCOSIDASES BY TETRAZOLES AND OTHER MANNOSE MIMICS (1995) (32)
Influence of preparation procedure on polymer composition: synthesis and characterisation of polymethacrylates bearing β-D-glucopyranoside and β-D-galactopyranoside residues (2002) (31)
Building Up Key Segments of N-Glycans in the Gas Phase: Intrinsic Structural Preferences of the α(1,3) and α(1,6) Dimannosides (2006) (31)
Adding water to sugar: A spectroscopic and computational study of α- and β-phenylxyloside in the gas phase (2005) (31)
Solvent interactions and conformational choice in a core N-glycan segment: gas phase conformation of the central, branching trimannose unit and its singly hydrated complex. (2008) (31)
Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase* (2011) (31)
Ligand amplification in a dynamic combinatorial glycopeptide library. (2005) (30)
ESI-MS assay of M. tuberculosis cell wall antigen 85 enzymes permits substrate profiling and design of a mechanism-based inhibitor. (2011) (30)
Developing Promiscuous Glycosidases for Glycoside Synthesis: Residues W433 and E432 in Sulfolobus solfataricus β‐Glycosidase are Important Glucoside‐ and Galactoside‐Specificity Determinants (2005) (29)
Exploring carbohydrate-peptide interactions in the gas phase: structure and selectivity in complexes of pyranosides with N-acetylphenylalanine methylamide. (2011) (29)
Genetic Incorporation of Olefin Cross-Metathesis Reaction Tags for Protein Modification. (2018) (29)
Synthetic Nucleosomes Reveal that GlcNAcylation Modulates Direct Interaction with the FACT Complex (2016) (28)
Site‐Selective Traceless Staudinger Ligation for Glycoprotein Synthesis Reveals Scope and Limitations (2011) (28)
Inhibition of naringinase (L-rhamnosidase) by piperidine analogues of L-rhamnose: Scaffolds for libraries incorporating trihydroxypipecolic acids (1996) (27)
Synthesis of Glycoproteins (2002) (27)
‘Naked’ and Hydrated Conformers of the Conserved Core Pentasaccharide of N-linked Glycoproteins and Its Building Blocks (2013) (26)
Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology (2009) (26)
Peptide secondary structures in the gas phase: consensus motif of N-linked glycoproteins. (2009) (26)
Plasmachemical Amine Functionalization of Porous Polystyrene Beads: The Importance of Pore Architecture (2002) (26)
Safe and Scalable Preparation of Barluenga's Reagent (2011) (25)
XPS studies of Pt—Sn naphtha reforming catalysts (1990) (25)
Carbohydrate hydration: heavy water complexes of α and β anomers of glucose, galactose, fucose and xylose. (2011) (25)
From Disulfide‐ to Thioether‐Linked Glycoproteins. (2008) (24)
Reagent switchable stereoselective beta(1,2) mannoside mannosylation: OH-2 of mannose is a privileged acceptor. (2008) (24)
Lectin-directed enzyme activated prodrug therapy (LEAPT): Synthesis and evaluation of rhamnose-capped prodrugs (2010) (24)
Chemical polyglycosylation and nanolitre detection enables single-molecule recapitulation of bacterial sugar export. (2016) (24)
Precise structure activity relationships in asymmetric catalysis using carbohydrate scaffolds to allow ready fine tuning: dialkylzinc-aldehyde additions. (2003) (24)
Controlled site-selective protein glycosylation for precise glycan structure-catalytic activity relationships. (2000) (23)
A tuneable method for N-debenzylation of benzylamino alcohols. (2005) (23)
A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase. (2017) (23)
Comparison of the effect of pore architecture and bead size on the extent of plasmachemical amine functionalisation of poly(styrene-co-divinylbenzene) permanently porous resins (2004) (22)
Site-selective glycosylation of subtilisin Bacillus lentus causes dramatic increases in esterase activity. (2000) (22)
Chemically modified "polar patch" mutants of subtilisin in peptide synthesis with remarkably broad substrate acceptance: designing combinatorial biocatalysts. (2002) (22)
Diversification in substrate usage by glutathione synthetases from soya bean (Glycine max), wheat (Triticum aestivum) and maize (Zea mays). (2005) (22)
Synthesis and solution-phase conformation of the RG-I fragment of the plant polysaccharide pectin reveals a modification-modulated assembly mechanism. (2010) (22)
Chemical site-selective prenylation of proteins. (2008) (21)
Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry. (2010) (21)
Biocatalysis and Enzymes in Organic Synthesis (2002) (21)
Isotopic hydration of cellobiose: vibrational spectroscopy and dynamical simulations. (2011) (21)
Creation of a gated antibody as a conditionally functional synthetic protein (2014) (20)
Plasmachemical Amine Functionalization of Porous Polystyrene Spheres: The Importance of Particle Size (2003) (20)
Glycomimetic Inhibitors of Mycobacterial Glycosyltransferases: Targeting the TB Cell Wall (2008) (20)
A trisulfide-linked glycoprotein. (2007) (20)
Monitoring the Disassembly of Virus-like Particles by 19F-NMR (2017) (20)
Accessible sugars as asymmetric olefin epoxidation organocatalysts: glucosaminide ketones in the synthesis of terminal epoxides. (2009) (20)
Heavy water hydration of mannose: the anomeric effect in solvation, laid bare (2011) (19)
Studying glycobiology at the single-molecule level (2018) (19)
Flow chemistry kinetic studies reveal reaction conditions for ready access to unsymmetrical trehalose analogues. (2010) (19)
Peptide templated glycosidic bond formation: a new strategy for oligosaccharide synthesis† (1999) (19)
Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites (2017) (19)
High-dose daptomycin for the treatment of endocarditis caused by Staphylococcus aureus with intermediate susceptibility to glycopeptides. (2010) (18)
Caesium Trifluoroacetate Displacement of Triflates in the Inversion of Alcohols (1997) (18)
Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis (2021) (18)
Post-translational mutagenesis for installation of natural and unnatural amino acid side chains into recombinant proteins (2017) (17)
Expanding the utility of proteases in synthesis: broadening the substrate acceptance in non-coded amide bond formation using chemically modified mutants of subtilisin (2001) (17)
Creation of an α-mannosynthase from a broad glycosidase scaffold. (2012) (17)
Post-translational site-selective protein backbone α-deuteration (2018) (17)
Chemical Protein Modification (2010) (16)
Solid phase peptide templated glycosidic bond formation (2003) (16)
Ready protease-catalyzed synthesis of carbohydrate-amino acid conjugates. (2001) (16)
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome (2021) (15)
Inverted regioselectivity of C-H amination: Unexpected oxidation at beta- rather than gamma-C-H. (2010) (15)
The controlled introduction of multiple negative charge at single amino acid sites in subtilisin Bacillus lentus. (1999) (15)
The controlled glycosylation of a protein with a bivalent glycan: towards a new class of glycoconjugates, glycodendriproteins (2001) (14)
Towards an unprotected self-activating glycosyl donor system: Bromobutyl glycosides (2002) (14)
Conformational effects in sugar ions: spectroscopic investigations in the gas phase and in solution (2012) (13)
NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis (2015) (13)
GLYCOPROTEIN SYNTHESIS : FROM GLYCOBIOLOGICAL TOOLS TO TAILOR-MADE CATALYSTS (1999) (13)
Altering the specificity of subtilisin Bacillus lentus through the introduction of positive charge at single amino acid sites. (1999) (13)
Kinetic and thermodynamic azides from α-triflates of γ-lactones: intermediates for the incorporation of polyhydroxylated D- and L-α-aminoacids into combinatorial libraries (1996) (13)
Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing (2007) (13)
Glycosylation of the primary binding pocket of a subtilisin protease causes a remarkable broadening in stereospecificity in peptide synthesis (2001) (12)
Control of phosphoryl migratory transesterifications allows regioselecive access to sugar phosphates. (2013) (12)
Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein. (2009) (12)
Synthesis and characterization of WS2 inorganic nanotubes with encapsulated/intercalated CsI (2010) (11)
Managing symptomatic drug-induced liver injury in HIV-hepatitis C virus-coinfected patients: a role for interferon. (2007) (11)
Glycosyldiselenides as lectin ligands detectable by NMR in biofluids. (2015) (11)
Biochemistry. Mimicking posttranslational modifications of proteins. (2004) (11)
Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity (2018) (11)
"Polar patch" proteases as glycopeptiligases. (2005) (10)
Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein (2014) (10)
Rewritable glycochips. (2009) (10)
Furanosic forms of sugars: conformational equilibrium of methyl β-d-ribofuranoside. (2016) (10)
Modular control of lectin function: redox-switchable agglutination. (2004) (10)
Chain-growth polyglycosylation: synthesis of linker-equipped mannosyl oligomers. (2015) (10)
High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. (2011) (10)
Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels (2019) (9)
Ready display of antigenic peptides in a protein 'mimogen'. (2016) (9)
The interaction between social protection and agriculture (2013) (9)
A Convenient Catalyst for Aqueous and Protein Suzuki—Miyaura Cross‐Coupling. (2010) (9)
Selective Protein Degradation by Ligand‐Targeted Enzymes: Towards the Creation of Catalytic Antagonists (2003) (9)
Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars (2020) (8)
Grand Challenges in Chemistry for 2016 and Beyond (2016) (8)
In vivo behaviour of glyco-NaI@SWCNT ‘nanobottles’ (2019) (8)
Probing the glycosidic linkage: secondary structures in the gas phase (2008) (7)
Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar. (2013) (7)
Probing the limits of Q-tag bioconjugation of antibodies† †Electronic supplementary information (ESI) available: Methods section including the synthesis of Ab-labelling reagents, Ab conjugation methods, chromatography and native MS. See DOI: 10.1039/c9cc02303h (2019) (7)
Photoinduced, family-specific, site-selective cleavage of TIM-barrel proteins. (2009) (7)
The expanding roles of biocatalysis and biotransformation (2006) (7)
2 Synthetic methods : Part (iii) Biocatalysis and enzymes in organic synthesis (2003) (7)
Polymer backbone conformation--a challenging task for database information retrieval. (2009) (6)
Household Income Generation Strategies (2012) (6)
Residue-Selective Protein C-Formylation via Sequential Difluoroalkylation-Hydrolysis (2021) (6)
Proteins as templates for complex synthetic metalloclusters: towards biologically programmed heterogeneous catalysis (2016) (6)
The linear assembly of a pure glycoenzyme. (2009) (6)
Post-translational insertion of boron in proteins to probe and modulate function (2021) (5)
Could You Patent the Sun? (2021) (5)
Molecular MRI approaches to the detection of CNS inflammation. (2011) (5)
3 – Synthesis and Activation of Carbohydrate Donors: Acetates, Halides, Phenyl selenides and Glycals (2003) (5)
Synthetic Phosphorylation of p 38 α Recapitulates Protein Kinase Activity (2014) (5)
Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines. (2016) (5)
Controlled Polymer Synthesis — From Biomimicry Towards Synthetic Biology (2010) (5)
Vignette: Extending the Application of Metathesis in Chemical Biology – The Development of Site‐Selective Peptide and Protein Modifications (2015) (4)
Glycans in nanotechnology (2017) (4)
Hydroxyurea for HIV infection. (1998) (4)
CHAPTER 5:Synthetic Protein Biologics (2013) (4)
Severe babesiosis in a patient treated with a tumor necrosis factor α antagonist. (2012) (4)
Cryptic SARS-CoV2-spike-with-sugar interactions revealed by 'universal' saturation transfer analysis — Source link (4)
2 Synthetic methods (2000) (3)
Enzymatic glycosynthesis GeTs better. (2007) (3)
Glyco-SeS: Selenenylsulfide-Mediated Protein Glycoconjugation — A New Strategy in Post-Translational Modification. (2004) (3)
Phosphine-Free Suzuki—Miyaura Cross-Coupling in Aqueous Media Enables Access to 2-C-Aryl-glycosides. (2012) (3)
Chemical Methods for Mimicking Post-Translational Modifications (2009) (3)
ACS Awards 2017. (2017) (2)
Tetrazoles of Manno- and Rhamnofuranoses. (2010) (2)
The Controlled Glycosylation of a Protein with a Bivalent Glycan: Towards a New Class of Glycoconjugates, Glycodendriproteins. (2001) (2)
Tetrazoles of Manno- and Rhamno-Pyranoses: Inhibition of Glycosidases by Tetrazoles and Other Mannose Mimics. (1996) (2)
A Triply Divergent Reagent for Glycoprotein Synthesis (2015) (2)
Inhibition of Naringinase (L‐Rhamnosidase) by Piperidine Analogues of L‐Rhamnose: Scaffolds for Libraries Incorporating Trihydroxypipecolic Acids. (1997) (2)
Plasmachemical surface functionalised beads: versatile tailored supports for polymer assisted organic synthesis. (2004) (2)
Synthesis of a C-galactoside suitable for protein modification by Cu-catalyzed cycloaddition (2007) (2)
Hand in glove (2)
Chemically Modified “Polar Patch” Mutants of Subtilisin in Peptide Synthesis with Remarkably Broad Substrate Acceptance: Designing Combinatorial Biocatalysts. (2003) (2)
Synthesis and Activation of Carbohydrate Donors: Acetates, Halides, Phenyl Selenides and Glycals (2004) (2)
Tristriazole ligand for use in the Cu-Catalyzed [3+2] azide-alkyne cycloaddition on protein surfaces (2007) (2)
1.15 – Synthesis of Glycopeptides and Glycoproteins (2007) (2)
12 – The Uses of Glycoprocessing Enzymes in Synthesis (2003) (2)
The Uses of Glycoprocessing Enzymes in Synthesis (2004) (2)
Income generation strategies among Nicaraguan agricultural producers. (2001) (2)
Enzyme catalysis: sweet flexibility. (2010) (2)
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP (2017) (1)
L‐(+)‐Swainsonine and Other Pyrrolidine Inhibitors of Naringinase: Through an Enzymic Looking Glass from D‐Mannosidase to L‐Rhamnosidase? (1997) (1)
Strategies in the Design and Use of Synthetic "Internal Glycan" Vaccines. (2017) (1)
Multiplexed synchrotron X-Ray fluorescence imaging of brain inflammation using targeted heavy metal nanoparticles (2015) (1)
Expanding the Utility of Proteases in Synthesis: Broadening the Substrate Acceptance in Non-coded Amide Bond Formation Using Chemically Modified Mutants of Subtilisin. (2001) (1)
Olefin Metathesis for Site-Selective Protein Modification (2009) (1)
Glycoproteins Glyco-SeS : Selenenylsulfide-Mediated Protein Glycoconjugation — A New Strategy in Post-Translational Modification * * (2004) (1)
Synthetic Protein Biologics (2014) (1)
Polyfluoropyridyl Glycosyl Donors (2008) (1)
Recent Biotechnological Applications of Glyconanomaterials (2013) (1)
Structure and activity of a flavonoid 3-0 glucosyltransferase reveals the basis for plant natural product modification (2006) (1)
A Tuneable Method for N‐Debenzylation of Benzylamino Alcohols. (2005) (1)
Reductive site-selective atypical C,Z-type/N2-C2 cleavage allows C-terminal protein amidation (2022) (1)
2 Synthetic methods : Part (v) Enzyme methods (2002) (1)
Erratum: Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection (2013) (1)
Tetrazoles of manno- and rhamno-furanoses (1995) (1)
Direct Deprotected Glycosyl—Asparagine Ligation. (2006) (1)
Building up key segments of N-glycans in the gas phase: intrinsic structural preferences of the alpha(1,3) and alpha(1,6) dimannosides. (2006) (1)
Peptide Templated Glycosylation Reaction. (2000) (1)
Stereoretentive Post-Translational Protein Editing (2022) (1)
Laser spectroscopic study on the conformations and the hydrated structures of benzo-18-crown-6-ether and dibenzo-18-crown-6-ether in supersonic jets (2007) (1)
Relational uncertainty between frenemies in forensics (2016) (1)
From History to Tomorrow: Space Programs in Africa (2020) (1)
Clark, Ian. International Legitimacy and World Society (2008) (1)
ICODR 2003: Helping Humanity Progress (2003) (1)
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering (2007) (1)
Modification of fulleropyrazolines modulates their cleavage by light. (2014) (1)
Outperforming Nature’s Catalysts: Designing Metalloenzymes for Chemical Synthesis (2017) (1)
Editorial Overview: Nanotechnology and biotechnology: Two way traffic. (2017) (0)
Substrate and Metal Ion Promiscuity in Mannosylglycerate (2011) (0)
Exploring and Exploiting the Therapeutic Potential of Glycoconjugates (2006) (0)
Post‐translational Modification of Protein Biopharmaceuticals. Edited by Gary Walsh. (2010) (0)
Crystal Structure of LuxP In Complex With L-xylulofuranose-1,2-borate (2016) (0)
Cover Picture: Glycoviruses: Chemical Glycosylation Retargets Adenoviral Gene Transfer (Angew. Chem. Int. Ed. 7/2005) (2005) (0)
Post-translational mutagenesis: a chemical synthetic strategy for exploration of protein side-chain diversity (2016) (0)
Synthetic Methods. Part 5. Enzyme Methods (2003) (0)
Distributable, Metabolic PET Reporting of Tuberculosis (2023) (0)
Hydride Reductions and 1,2‐Additions of Nucleophiles to Carbonyl Compounds Using Carbohydrate‐Based Reagents and Additives (2013) (0)
BMC preface. (2013) (0)
Dissecting tunicamycin biosynthesis: a potent carbohydrate processing enzyme inhibitor (2010) (0)
Intact Nucleosomal Context Enables Chromodomain Reader MRG15 to Distinguish H3K36me3 from - Me2 (2020) (0)
An imaging medium with iron-containing colloidal particles conjugated to oligosaccharide (2006) (0)
Mannosylglycerate Synthase in Complex with Mn-GDP (2010) (0)
Publisher Correction: Post-translational insertion of boron in proteins to probe and modulate function (2021) (0)
Cover Picture: Selective Protein Degradation by Ligand‐Targeted Enzymes: Towards the Creation of Catalytic Antagonists (ChemBioChem 6/2003) (2003) (0)
With a carbohydrate group chemically modified proteins (1999) (0)
What can we Expect of High-Resolution Spectroscopies on Carbohydrates? (2015) (0)
Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2 (2020) (0)
Glycosyldisulfides: A New Class of Solution and Solid Phase Glycosyl Donors. (2001) (0)
Peptide Templated Glycosidic Bond Formation. A New Strategy for Oligosaccharide Synthesis. (1999) (0)
DISCOVERY OF A SELECTIVE LYSOSOMAL ALPHA-MANNOSIDASE INHIBITOR FROM AN IMINO-SUGAR LIBRARY (2014) (0)
Spectral signatures and structural motifs in isolated and hydrated monosaccharides: phenyl alpha- and beta-l-fucopyranoside. (2006) (0)
The sugar code: emerging biomedical perspectives (2005) (0)
Carbohydrate-Derived Amino Alcohol Ligands for Asymmetric Alkynylation of Aldehydes. (2006) (0)
Structure of a novel NAD dependent-NDP-hexosamine 5,6-dehydratase, TunA, involved in tunicamycin biosynthesis (2012) (0)
Crystal Structure of LuxP In Complex With a Formose Derived AI-2 Analogue (2016) (0)
A Silver-Lined Anniversary of Fleet Iminosugars: 1984-2009, from DIM to DRAM to LABNAc (2009) (0)
Mannosylglycerate Synthase in Complex with Mg-GDP-Mannose (2010) (0)
ANTIFREEZE GLYCOPEPTIDES: A STRUCTURAL APPROACH TO ENGINEER ANTIFREEZE PROTEINS (2020) (0)
Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase (2016) (0)
Focusing Antibody Responses to Specific Protein Surfaces Through Site-Selective Glycan Addition (2013) (0)
Glycosylation of the Primary Binding Pocket of a Subtilisin Protease Causes a Remarkable Broadening in Stereospecificity in Peptide Synthesis. (2001) (0)
Glycoviruses Glycoviruses : Chemical Glycosylation Retargets Adenoviral Gene Transfer * * (2005) (0)
Adding water to sugar: a spectroscopic and computational study of alpha- and beta-phenylxyloside in the gas phase. (2005) (0)
GLYCOSYLATION VIA INTRAMOLECULAR TRANSFER (G.I.T.) (2002) (0)
Unravelling the biological roles of charged carbohydrates (2011) (0)
Cover Picture: A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Angew. Chem. Int. Ed. 21/2007) (2007) (0)
“Polar Patch” Proteases as Glycopeptiligases. (2005) (0)
Posttranslational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance. (2023) (0)
Design and synthesis of nanoparticles functionalised with Lewis oligosaccharides for selective targeting of DC-SIGN (2014) (0)
Structure of LuxP In Complex With 1-deoxy-alpha-L-xylulofuranose-1,2-borate (2016) (0)
Significant reduction in monocyte production of both plasminogen activator inhibitors PAI-2 and PAI-1 is achieved by transfection with PAI-2-specific antisense oligonucleotide sequences (2004) (0)
LanCLs have C-glutathionylation activity with potential to trap the eliminylome (2020) (0)
Trehalose 6-phosphate, a novel protein kinase inhibitor (2008) (0)
MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH Manganese and GDP (2011) (0)
Microparticles bearing RGD peptide promote integrin alpha v beta 3-dependent platelet adhesion in isolated, pressurized cerebral artery (2013) (0)
Mannosylglycerate Synthase in Complex with Lactate (2010) (0)
DNA Modification under Mild Conditions by Suzuki—Miyaura Cross‐Coupling for the Generation of Functional Probes. (2014) (0)
Intervention in plant signalling through light-activation of an exogenous sugar signalling-precursor increase crop yield and resilience (2015) (0)
CONFORMATIONAL STUDY OF DNA SUGARS: FROM THE GAS PHASE TO SOLUTION (2017) (0)
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form (2017) (0)
Abstract: Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism (2011) (0)
Site-specific 89Zr-herceptin. (2019) (0)
Faculty Opinions recommendation of Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. (2005) (0)
Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase (2010) (0)
Synthesis of fully deprotected glyco-MTS reagents (2007) (0)
Approaches to Building Chemical Cells/Chells: Examples of Relevant Mechanistic ‘Couples’ (2011) (0)
A Brief Manifesto for Chemical Ingenuity and Insight in the Heart of Biology: A Time is Right for Sophistication not Simplification? (2018) (0)
Spirituality and Space: An Historical Perspective (2019) (0)
Economics: An Integrated Approach (1997) (0)
Ermine Revolt (2018) (0)
Multimeric microparticles of iron oxide (mMPIO) for dual modality molecular imaging with CT & MRI (2014) (0)
Wzi, an Outer Membrane Protein Involved in Group 1 Capsule Assembly in Escherichia coli, is a Carbohydrate Binding Beta-Barrel (2013) (0)
Titelbild: Glycoviruses: Chemical Glycosylation Retargets Adenoviral Gene Transfer (Angew. Chem. 7/2005) (2005) (0)
Letter of Transmittal C Squared (2012) (0)
United Methodism in New England: A historical, organizational, and spiritual study (2005) (0)
Fighting Isolation and Celebrating Gender Diversity (2019) (0)
Protecting Systems from Within: Application-Level Observation and Control Mechanisms (2014) (0)
Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts (2022) (0)
Education, Oppression, and Democracy (2016) (0)
Mannosylglycerate Synthase in Complex with Mg-GDP (2010) (0)
Moving towards productive inclusion: Strengthening coherence between agriculture and social protection (2014) (0)
Mercy in Miami (2004) (0)
SUGARS AND ENZYMES: PROTEIN GLYCOSYLATION AND GLYCOSIDE SYNTHESIS (2002) (0)
Intellectual Disabilities Case (2015) (0)
MP-21.20 (2006) (0)
Apparatus and method for verifying honest gaming transactions in a communication network (1998) (0)
Obama and Libya (2011) (0)
Linking Social Protection and Agriculture in Sub-Saharan Africa (2014) (0)
Carbohydrate-Derived Amino alcohol Ligands for Asymmetric Reformatsky Reactions. (2005) (0)
Cover Picture: Exploring and Exploiting the Therapeutic Potential of Glycoconjugates (Chem. Eur. J. 3/2006) (2006) (0)
Carbon-Centered Radicals in Protein Manipulation (2023) (0)
Genetic Incorporation of Ole fi n Cross-Metathesis Reaction Tags for Protein Modi fi cation (2018) (0)
Probing Site‐Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins (2022) (0)
Trehalose signalling: understanding and exploiting an emerging small molecule paradigm (2007) (0)
CARBOHYDRATE MEDIATED ASYMMETRIC CATALYSIS (2002) (0)
Incorporation of unnatural trehalose analogs into Mycobacterium 1 tuberculosis : fluorescent probes of mycobacterial infection 2 (2013) (0)
SUGAR-PROTEIN HYBRIDS FOR BIOMEDICAL APPLICATIONS (2016) (0)
Glycoprotein Synthesis: From Glycobiological Tools to Tailor-Made Catalysts (1999) (0)
CORRECTIONS (2007) (0)
PLS models discriminate types of MS from spectroscopic analysis of plasma and urinele (2009) (0)
Synthetic Methods. Part 3. Biocatalysis and Enzymes in Organic Synthesis (2004) (0)
A novel glycoconjugation method and unexpected photo-induced site-selective protein cleavage reaction (2009) (0)
Titelbild: A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Angew. Chem. 21/2007) (2007) (0)
Synthesis of a O-propargyl glycoside suitable for protein modification by Cu(I)-catalyzed cycloaddition (2007) (0)
The Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One‐Pot Protein Glycoconjugation. (2006) (0)
Caesium Trifluoroacetate Displacement of Triflates in the Inversion of Alcohols. (1998) (0)
United States Patent ( 10 ) Patent No . : US 6 , 512 , 098 B 2 (2017) (0)
Our Invisible College (2016) (0)
Taking the Sting out of Tunicamycin: A Novel Approach Significantly Reduces the Cytotoxicity of this Nucleoside Antibiotic (2017) (0)
Novel Five-membered Ring Imino Sugar Derivatives Inhibit Flaviviruses via Distinct Mechanisms (2008) (0)
Oxidation and Reduction (2000) (0)
Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase (2005) (0)

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