Bennett Van Houten
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Bennett Van Houten's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Molecular Biology Stanford University
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(Suggest an Edit or Addition)Bennett Van Houten's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. (1997) (1718)
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts (2011) (624)
- Adipose tissue and adipocytes support tumorigenesis and metastasis. (2013) (554)
- Cell and tissue responses to oxidative damage. (1993) (523)
- Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro (2004) (519)
- Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells. (2000) (427)
- Standardizing global gene expression analysis between laboratories and across platforms (2005) (410)
- Role of mitochondrial DNA in toxic responses to oxidative stress. (2006) (393)
- Mitochondrial DNA repair and aging. (2002) (339)
- Prokaryotic nucleotide excision repair: the UvrABC system. (2006) (320)
- Nucleotide excision repair in Escherichia coli. (1990) (306)
- Role of mitochondria in toxic oxidative stress. (2005) (283)
- High-mobility group box 1 is essential for mitochondrial quality control. (2011) (259)
- Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. (2000) (244)
- Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. (2014) (242)
- Mitochondrial hTERT exacerbates free‐radical‐mediated mtDNA damage (2004) (230)
- Mitochondrial dysfunction in neurodegenerative diseases and cancer. (2010) (216)
- Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells. (1999) (207)
- Crucial roles for DNA ligase III in mitochondria but not in XRCC1-dependent repair (2011) (206)
- Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD (2008) (206)
- The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics (2014) (202)
- Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress (2014) (199)
- Cell Sorting Experiments Link Persistent Mitochondrial DNA Damage with Loss of Mitochondrial Membrane Potential and Apoptotic Cell Death* (2003) (198)
- Integrating phenotypic and expression profiles to map arsenic-response networks (2004) (191)
- Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species (2011) (190)
- Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients. (2003) (186)
- Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair (1999) (185)
- Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. (2006) (184)
- Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position. (1986) (181)
- Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease. (1985) (181)
- Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress (2012) (167)
- Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells* (2010) (166)
- Measuring oxidative mtDNA damage and repair using quantitative PCR. (2002) (162)
- Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts. (1997) (161)
- Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay (1992) (159)
- Prokaryotic nucleotide excision repair. (2013) (158)
- ATP13A2 regulates mitochondrial bioenergetics through macroautophagy (2012) (156)
- Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins (1986) (155)
- Metabolic symbiosis in cancer: Refocusing the Warburg lens (2013) (154)
- Importance of glycolysis and oxidative phosphorylation in advanced melanoma (2012) (152)
- ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. (2014) (152)
- Comparison of chemical reactivity, cytotoxicity, interstrand cross-linking and DNA sequence specificity of bis(platinum) complexes containing monodentate or bidentate coordination spheres with their monomeric analogues. (1990) (152)
- Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease (2014) (151)
- Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. (2010) (150)
- Repair of DNA damage in mitochondria. (1999) (149)
- 'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system. (2005) (133)
- Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. (2012) (132)
- Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease (2011) (127)
- Alterations in bioenergetics due to changes in mitochondrial DNA copy number. (2010) (123)
- APOPTOSIS INDUCED BY PERSISTENT SINGLE-STRAND BREAKS IN THE MITOCHONDRIAL GENOME: CRITICAL ROLE OF EXOG (5’ EXO/ENDONUCLEASE) IN THEIR REPAIR (2011) (122)
- Mitochondrial DNA damage induced autophagy, cell death, and disease. (2016) (118)
- Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base. (2002) (112)
- Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells* (2009) (110)
- Structural basis for DNA recognition and processing by UvrB (2006) (109)
- Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans (2007) (108)
- Mitochondrial Structure, Function and Dynamics Are Temporally Controlled by c-Myc (2012) (106)
- Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. (1998) (105)
- Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos. (1997) (101)
- Bcl-2 Facilitates Recovery from DNA Damage after Oxidative Stress (1999) (99)
- Reduction in frataxin causes progressive accumulation of mitochondrial damage. (2003) (97)
- UvrABC nuclease complex repairs thymine glycol, an oxidative DNA base damage. (1990) (97)
- The β-Hairpin Motif of UvrB Is Essential for DNA Binding, Damage Processing, and UvrC-mediated Incisions* (2002) (97)
- Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. (2006) (96)
- Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology (2010) (96)
- Structural insights into the first incision reaction during nucleotide excision repair (2005) (96)
- Mitochondrial Respiration - An Important Therapeutic Target in Melanoma (2012) (95)
- Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites. (1986) (95)
- Strand opening by the UvrA2B complex allows dynamic recognition of DNA damage (1999) (92)
- Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress (2002) (89)
- Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction. (2012) (89)
- Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice. (2012) (88)
- An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress (2012) (87)
- Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2 (2012) (87)
- Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. (2003) (84)
- Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells. (1998) (84)
- Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration (2018) (83)
- Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. (2012) (82)
- Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease. (1988) (80)
- DNase I footprint of ABC excinuclease. (1987) (79)
- Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells (2014) (78)
- 3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. (2005) (78)
- Repair of O6-methylguanine by ABC excinuclease of Escherichia coli in vitro. (1989) (78)
- Damage repertoire of the Escherichia coli UvrABC nuclease complex includes abasic sites, base-damage analogues, and lesions containing adjacent 5' or 3' nicks. (1990) (77)
- DNA damage in brain mitochondria caused by aging and MPTP treatment (2000) (77)
- Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression. (2018) (77)
- Mechanism of action of the Escherichia coli UvrABC nuclease: Clues to the damage recognition problem (1993) (76)
- Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin (2013) (76)
- Kinetic gating mechanism of DNA damage recognition by Rad4/XPC (2015) (75)
- The nucleotide excision repair protein UvrB, a helicase-like enzyme with a catch. (2000) (74)
- Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. (2005) (73)
- Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair (2012) (72)
- Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process. (2016) (70)
- Formation of DNA Repair Intermediates and Incision by the ATP-dependent UvrB-UvrC Endonuclease* (1997) (68)
- Analyzing the Handoff of DNA from UvrA to UvrB Utilizing DNA-Protein Photoaffinity Labeling*♦ (2004) (68)
- Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction (2019) (67)
- Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease (1987) (67)
- Sequence specificity of DNA-DNA interstrand cross-link formation by cisplatin and dinuclear platinum complexes. (1994) (66)
- Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts. (1988) (65)
- Construction of DNA substrates modified with psoralen at a unique site and study of the action mechanism of ABC excinuclease on these uniformly modified substrates. (1986) (64)
- Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair (2013) (64)
- Nucleotide excision repair in Escherichia coli (1990) (63)
- Structure of the C‐terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute‐like catalytic triad (2007) (63)
- DNA repair after oxidative stress: current challenges. (2018) (63)
- Involvement of Molecular Chaperonins in Nucleotide Excision Repair (1998) (62)
- B----Z DNA conformational changes induced by a family of dinuclear bis(platinum) complexes. (1992) (61)
- Interaction of novel bis(platinum) complexes with DNA. (1989) (61)
- Measuring gene-specific nucleotide excision repair in human cells using quantitative amplification of long targets from nanogram quantities of DNA. (2000) (60)
- Template integrity is essential for PCR amplification of 20- to 30-kb sequences from genomic DNA. (1995) (60)
- Mitochondrial toxicity in hearts of CD‐1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination (2007) (57)
- Ligand effects on platinum binding to DNA. A comparison of DNA binding properties for cis- and trans-[PtCl2(amine)2] (amine = NH3, pyridine). (1993) (57)
- Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase γ associated with progressive external ophthalmoplegia (2006) (57)
- The role of dynamin-related protein 1 in cancer growth: a promising therapeutic target? (2013) (56)
- Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. (2008) (56)
- Mitochondrial and nuclear DNA damage induced by 5-aminolevulinic acid. (2004) (56)
- SnapShot: Mitochondrial Quality Control (2011) (56)
- Damage sensor role of UV-DDB during base excision repair (2019) (56)
- Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair (2004) (55)
- Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism (2018) (55)
- Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates (2014) (55)
- In vivo formation and repair of cyclobutane pyrimidine dimers and 6-4 photoproducts measured at the gene and nucleotide level in Escherichia coli. (2000) (55)
- Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress (2005) (54)
- Role of XPD in cellular functions: To TFIIH and beyond. (2016) (54)
- Interaction of Escherichia coli RNA polymerase with DNA in an elongation complex arrested at a specific psoralen crosslink site. (1988) (53)
- Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes (2013) (53)
- Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure. (2010) (52)
- The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination (2013) (52)
- Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases. (2003) (52)
- Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. (2013) (52)
- Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. (2011) (51)
- Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer (2018) (51)
- The C-terminal Zinc Finger of UvrA Does Not Bind DNA Directly but Regulates Damage-specific DNA Binding* (2006) (51)
- DNA damage in normally and prematurely aged mice (2013) (51)
- Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE. (1995) (51)
- Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. (2009) (49)
- Structural and Functional Characterization of the Human DNA Repair Helicase XPD by Comparative Molecular Modeling and Site-directed Mutagenesis of the Bacterial Repair Protein UvrB* (2003) (49)
- Mitochondrial division inhibitor 1 (mdivi-1) enhances death receptor-mediated apoptosis in human ovarian cancer cells. (2015) (48)
- Overexpression of Mitochondrial Sirtuins Alters Glycolysis and Mitochondrial Function in HEK293 Cells (2014) (48)
- Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu. (1999) (48)
- UvrB Domain 4, an Autoinhibitory Gate for Regulation of DNA Binding and ATPase Activity* (2006) (47)
- Homodinuclear (Pt,Pt) and heterodinuclear (Ru,Pt) metal compounds as DNA-protein cross-linking agents: potential suicide DNA lesions. (1993) (47)
- Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency (2018) (45)
- DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway (2009) (45)
- PCR-Based Assays for the Detection and Quantitation of DNA Damage and Repair (1996) (43)
- A cut above: Discovery of an alternative excision repair pathway in bacteria (2002) (43)
- Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins (2020) (43)
- DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. (2008) (42)
- Identification of Residues within UvrB That Are Important for Efficient DNA Binding and Damage Processing* (2004) (41)
- The Transition of Closely Opposed Lesions to Double-Strand Breaks during Long-Patch Base Excision Repair Is Prevented by the Coordinated Action of DNA Polymerase δ and Rad27/Fen1 (2008) (40)
- Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers (2018) (39)
- Cooperative damage recognition by UvrA and UvrB: identification of UvrA residues that mediate DNA binding. (2008) (38)
- Studying protein-DNA interactions using atomic force microscopy. (2018) (38)
- Butadiene-induced Intrastrand DNA Cross-links: A Possible Role in Deletion Mutagenesis* (2000) (37)
- Utilization of DNA photolyase, pyrimidine dimer endonucleases, and alkali hydrolysis in the analysis of aberrant ABC excinuclease incisions adjacent to UV-induced DNA photoproducts. (1987) (37)
- Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. (2007) (37)
- Proceedings of a workshop on DNA adducts: biological significance and applications to risk assessment Washington, DC, April 13-14, 2004. (2005) (36)
- The role of CSA and CSB protein in the oxidative stress response (2013) (36)
- Effects on DNA Damage and/or Repair Processes as Biological Mechanisms Linking Psychological Stress to Cancer Risk. (2014) (35)
- Genotoxicity of formaldehyde and an evaluation of its effects on the DNA repair process in human diploid fibroblasts. (1986) (35)
- Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. (2010) (35)
- Integrated Proteomic and Metabolic Analysis of Breast Cancer Progression (2013) (35)
- Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. (2006) (34)
- High Mobility Group Box 1 (HMGB1) Phenotypic Role Revealed with Stress (2014) (34)
- Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. (2012) (33)
- Functional Characterization of 8-Oxoguanine DNA Glycosylase of Trypanosoma cruzi (2012) (33)
- Dynamics of lesion processing by bacterial nucleotide excision repair proteins. (2012) (32)
- High resolution mapping of UV-induced photoproducts in the Escherichia coli lacI gene. Inefficient repair of the non-transcribed strand correlates with high mutation frequency. (1994) (31)
- Identification of a Chemical That Inhibits the Mycobacterial UvrABC Complex in Nucleotide Excision Repair† (2011) (29)
- Quantifying Metabolic Heterogeneity in Head and Neck Tumors in Real Time: 2-DG Uptake Is Highest in Hypoxic Tumor Regions (2014) (29)
- Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase. (2003) (28)
- TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity (2014) (28)
- Phototoxicity in Human Retinal Pigment Epithelial Cells Promoted by Hypericin, a Component of St. John’s Wort † (2007) (27)
- Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcription (2014) (27)
- Initiation of the UvrABC nuclease cleavage reaction. Efficiency of incision is not correlated with UvrA binding affinity. (1991) (27)
- Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. (2009) (26)
- NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution. (2007) (25)
- DNA repair gets physical: mapping an XPA-binding site on ERCC1. (2008) (25)
- Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission (2013) (24)
- Differential incision of bulky carcinogen-DNA adducts by the UvrABC nuclease: comparison of incision rates and the interactions of Uvr subunits with lesions of different structures. (2000) (24)
- Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β (2011) (24)
- The inhibition of ultraviolet radiation-induced DNA repair in human diploid fibroblasts by arabinofuranosyl nucleosides. (1984) (22)
- POLB: A new role of DNA polymerase beta in mitochondrial base excision repair. (2017) (22)
- Studies on the inhibition of repair of ultraviolet- and methyl methanesulfonate-induced damage in the DNA of human fibroblasts by novobiocin. (1982) (22)
- A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi‐1 (2015) (22)
- Rad4 recognition-at-a-distance: Physical basis of conformation-specific anomalous diffusion of DNA repair proteins. (2017) (21)
- AGE-DEPENDENT CHANGES IN INTERVERTEBRAL DISC CELL MITOCHONDRIA AND BIOENERGETICS (2018) (21)
- Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells. (2015) (21)
- DNA Damage: Effects on DNA Structure and Protein Recognition. Proceedings of a conference. Burlington, Vermont, July 31-August 4, 1993. (1994) (21)
- Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells. (2016) (20)
- Quantitation of carcinogen-induced DNA damage and repair in human cells with the UVR ABC excision nuclease from Escherichia coli. (1986) (20)
- Bioenergetic analysis of intact mammalian cells using the Seahorse XF24 Extracellular Flux analyzer and a luciferase ATP assay. (2014) (20)
- Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes. (2012) (20)
- Oxidative stress-induced senescence markedly increases disc cell bioenergetics (2019) (19)
- Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time. (2017) (19)
- Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts (2010) (19)
- Investigation of bacterial nucleotide excision repair using single-molecule techniques (2014) (19)
- Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe (2015) (19)
- Adipose tissue and adipocytes supports tumorigenesis and metastasis (2013) (19)
- Hydrophobic forces dominate the thermodynamic characteristics of UvrA-DNA damage interactions. (1998) (18)
- Chemical reactivity and DNA sequence specificity of formally monofunctional and bifunctional bis(platinum) complexes. (1994) (18)
- Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines. (2002) (18)
- A general path for large-scale solubilization of cellular proteins: from membrane receptors to multiprotein complexes. (2013) (18)
- Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer. (2020) (17)
- The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak. (2015) (17)
- XPB helicase regulates DNA incision by the Thermoplasma acidophilum endonuclease Bax1. (2012) (17)
- Equilibrium and stop-flow kinetic studies of fluorescently labeled DNA substrates with DNA repair proteins XPA and replication protein A. (2002) (17)
- Development of long PCR techniques to analyze deletion mutations of the human hprt gene. (1998) (17)
- Apoptosis Induced by Persistent Single-strand Breaks in Mitochondrial Genome (2011) (17)
- Inhibiting Autophagy During Interleukin 2 ( IL-2 ) Immunotherapy Promotes Long Term Tumor Regression (2012) (16)
- The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway (2019) (16)
- Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival (2017) (16)
- Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins (2022) (16)
- Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease (2008) (15)
- Bioenergetic analysis of intact mammalian cells using the Seahorse XF24 Extracellular Flux analyzer and a luciferase ATP assay. (2014) (15)
- PARP1: Structural insights and pharmacological targets for inhibition. (2021) (13)
- The accumulation of DNA breaks due to incision; comparative studies with various inhibitors. (1984) (12)
- Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity (2020) (12)
- Eukaryotic Nucleotide Excision Repair (2016) (12)
- Pulmonary Arterial Hypertension Is Associated with Oxidative Stress-induced Genome Instability. (2015) (12)
- Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening (2021) (12)
- Supercoiled DNA promotes formation of intercalated cis-N2-deoxyguanine adducts and base-stacked trans-N2-deoxyguanine adducts by (+)-7R,8S-dihydrodiol-9S,10R-epoxy-7,8,9,10-tetra- hydrobenzo[a]pyrene. (2004) (11)
- Robust incision of Benoz[a]pyrene-7,8-dihyrodiol-9,10-epoxide-DNA adducts by a recombinant thermoresistant interspecies combination UvrABC endonuclease system. (2006) (11)
- Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search (2020) (11)
- Quantitative Proteomics Reveal ATM Kinase-dependent Exchange in DNA Damage Response Complexes (2012) (10)
- Addendum: Standardizing global gene expression analysis between laboratories and across platforms (2005) (10)
- Nucleotide Excision Repair from Bacteria to Humans: Structure–Function Studies (2011) (10)
- The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer (2021) (9)
- Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase g associated with progressive external ophthalmoplegia (2006) (9)
- Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover (2021) (9)
- Bax1 Is a Novel Endonuclease (2009) (9)
- Single molecule techniques in DNA repair: a primer. (2014) (8)
- Mitochondrial dysfunction in neurodegenerative diseases and cancer (2010) (8)
- Sick mitochondria cause telomere damage: implications for disease (2019) (8)
- Activity of nucleotide excision repair enzymes for oxanine cross-link lesions. (2005) (7)
- Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs (2020) (7)
- Pulmonary Arterial Hypertension Is Associated with Oxidative Stress-induced Genome Instability. (2015) (7)
- Reduced sulfhydryls maintain specific incision of BPDE-DNA adducts by recombinant thermoresistant Bacillus caldotenax UvrABC endonuclease. (2003) (6)
- Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes (2019) (6)
- Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential (2017) (5)
- Transcriptional pausing to scout ahead for DNA damage (2014) (5)
- Searching for DNA Damage: Insights From Single Molecule Analysis (2021) (5)
- Dispersed single wall carbon nanotubes do not impact mitochondria structure or function, but technical issues during analysis could yield incorrect results. (2017) (4)
- Toxin-Mediated Complex I Inhibition and Parkinson’s Disease (2016) (4)
- Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration (2018) (4)
- Survival choices (2006) (4)
- Meeting report: EU-US Workshop on Molecular Signatures of DNA Damage-Induced Stress Responses. Cortona, Italy, 26-30 September 2003. (2004) (3)
- Damage Recognition by the Bacterial Nucleotide Excision Repair Machinery (2005) (3)
- Huntington’s Disease: Astrocytes Shift to Fatty Acid Metabolism (2019) (3)
- Repair in Escherichia coli (3)
- A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characterization of NER. (2016) (3)
- Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair (2021) (2)
- Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing. (2020) (2)
- Repair of benzo[a]pyrene diol epoxide damaged bacteriophage T7 DNA determined by survival of phage made by in vitro packaging. (1985) (2)
- DNA damage, mutations, cancer, and aging. American Association for Cancer Research Special Conference: Cellular Responses to Environmental DNA Damage, Banff, AB, Canada, December 1-6, 1991. (1992) (2)
- Integrating multiple views of the cell: DNA repair jumps to higher level at Stowe workshop. (2006) (2)
- Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE) (2022) (2)
- Fourth DNA repair workshop on DNA damage and repair: mechanisms and biological consequences Smolenice Castle, 2-5 May 2004. (2004) (2)
- Promotes Long-term Tumor Regression Inhibiting Systemic Autophagy during Interleukin 2 Immunotherapy (2012) (2)
- Nucleotide excision repair of DNA adducts derived from the binding of the equine estrogen metabolite 4-OHEN to dC and dA adducts in vitro. (2006) (2)
- Meeting report. Second EU-US workshop on systems level understanding of DNA damage responses. (2006) (2)
- Mitochondrial behavior during nuclear and mitochondrial DNA repair in Trypanosoma cruzi epimastigotes. (2020) (1)
- Single molecule approaches: watching DNA repair one molecule at a time. Preface. (2014) (1)
- Cooperative interaction between AAG and UV-DDB in the removal of modified bases (2022) (1)
- The Use of Seahorse Extracellular Flux Analyzer in Mechanistic Studies of Naturally Occurring Cancer Chemopreventive Agents (2014) (1)
- Down-regulation of Bioenergetics in a Cellular Model of Friedreich's Ataxia: Frataxin Deficiency Affects Formation of Respiratory Supercomplexes and Glycolysis (2012) (1)
- DNA repair: Clamping down on copy errors (2016) (1)
- Abstract B37: Targeting tumor-stroma metabolic symbiosis for head and neck cancer therapy (2016) (1)
- Fine‐Mapping DNA Damage in E. Coli a (1994) (1)
- Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcription: Specialization of T. brucei nucleotide excision repair (2014) (1)
- Single-cell mutagenic responses and cell death revealed in real time (2018) (1)
- Protective Role of Mitochondrial Vitamin E in Toxic Oxidative Stress (2005) (1)
- Bax 1 Is a Novel Endonuclease IMPLICATIONS FOR ARCHAEAL NUCLEOTIDE EXCISION REPAIR * (2009) (1)
- Investigating the metabolic relationship between ovarian cancer cells and adipocytes: The role of fatty acid beta-oxidation (2015) (1)
- Nucleotide Excision Repair, Bacterial: The UvrABCD System (2004) (1)
- A Novel DNA Repair Mechanism for the Processing of Low-Level UV-Induced Damage in Bacteria (2018) (1)
- Molecular cartography of mutational landscapes in melanomas (2017) (1)
- Kunkel on DNA Replication Fidelity (1996) (1)
- Peakforce Tapping AFM Reveals that Human XPA Binds to DNA Damage as a Monomer Producing a 60° Bend (2018) (1)
- 3rd US-EU workshop: systems level understanding of DNA damage responses. (2010) (1)
- Regulating the San Francisco Sound: How a Music Venue Crackdown Inspired Pioneering Advancements in Entertainment Regulation and Support (2020) (1)
- Author response: Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity (2020) (1)
- Targeting Mitochondrial Function with Chemoptogenetics (2022) (1)
- The role of UV-DDB in processing 8-oxoguanine during base excision repair (2022) (1)
- Prokaryotic Nucleotide Excision Repair: The UvrABC System (2006) (1)
- Tirapazamine-induced damage in mitochondria and nuclear DNA under hypoxic and aerobic conditions in mammalian cells (1998) (0)
- Abstract 1259: c-Myc influences mitochondrial structure and function by regulating fusion and fission (2011) (0)
- The life and legacy of Sam Wilson (1939-2021). (2021) (0)
- Abstract 852: Apoptosis induction by ayurvedic medicine constituent withaferin A in human breast cancer cells is mediated by reactive oxygen species-dependent activation of Bak (2011) (0)
- Quantitative PCR: a sensitive biomarker of gene-specific DNA damage and repair (2002) (0)
- Abstract B144: Elesclomol, an inducer of oxidative stress, targets oxidative phosphorylation (oxphos) in melanoma cells. (2011) (0)
- Oxidative Stress and Angiogenesis in Tumor Progression (2013) (0)
- Breast Cancer and the Use of Biolog's PM- M plates (2013) (0)
- WT UV-DDB Performs a 3D Search on DNA whereas the XP-E Mutant (K244E DDB2) Mutant Slides (2013) (0)
- Abc exonuclease induced repair of psoralen modified dna (1989) (0)
- Frataxin Deficeiency Alters Assembly of Mitocohndrial Electron Transport Supercomplexes. (2014) (0)
- Abstract 1683: Novel combination approach using platinum drugs and mitochondrial division inhibitor 1 (mdivi-1) overcomes platinum resistance by synergistically inducing mitochondrial outer membrane permeabilization (MOMP) and apoptosis independent of Drp1 (2014) (0)
- 82 Measurement of mitochondrial DNA damage in human cells adjusted for copy number by the combined use of real-time and quantitative (2010) (0)
- Repair ofN-Methyl-N'-Nitr o-N-Nitrosoguani dine-Induced (1987) (0)
- A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characterization of NER. (2016) (0)
- Mitochondrial DNA damage in vascular endothelial cells exposed to shear stress (2009) (0)
- Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism (2018) (0)
- Above and beyond. (2005) (0)
- Direct Visualization Of Joining of DNA Fragments By LigIIIβ Using Atomic Force Microscopy (2010) (0)
- Graphical snapshot of Samuel H. Wilson. (2020) (0)
- Real-world rehab. (2005) (0)
- Direct Visualization Of Joining of DNA Fragments By LigIIIβ Using Atomic Force Microscopy (2010) (0)
- Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium (2005) (0)
- Formation and Stability of E.Coli RecA Nucleoprotein Filament Regulated by Single-Stranded DNA Binding Protein (2013) (0)
- 120. Epinephrine-induced DNA damage in a human epithelial breast cell line (2014) (0)
- 1 dependent G2/M arrest and aneuploidy through DNA replication stress 2 (2012) (0)
- Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant N88A bound to its catalytic divalent cation (2005) (0)
- At the heart of all science is the generation and dissemination of data consistent or inconsistent with specific hypotheses. (2000) (0)
- Investigating Nucleotide Excision DNA Repair by Single-Molecule Imaging of Quantum Dot Labeled Proteins Reveals Unique Scanning Mechanisms (2011) (0)
- Folliculitis in Dark Skin? Go for the Nd:YAG Laser (2005) (0)
- Third EU-US workshop on "Nucleotide excision repair and crosslink repair-From molecules to mankind", Smolenice Castle, Slovak Republic, May 7th-11th 2017 (2017) (0)
- Decision letter: Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide (2021) (0)
- Abstract 5085: Inducing multipolarity of acentrosomal mitotic spindles as a novel tumor-specific targeting strategy revealed by the antimitotic effect of mdivi-1 (2014) (0)
- Editors' note on "p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1". (2022) (0)
- Stimulation of TDG by UV-DDB. (2023) (0)
- , Milan Activity Regulation of DNA Binding and ATPase UvrB Domain 4 , an Autoinhibitory Gate for Recombination : DNA : Replication , Repair (2006) (0)
- Robust Incision of BPDE-DNA Adducts by Recombinant Thermoresistant Interspecies Combination UvrABC Endonuclease System (2008) (0)
- Bioenergetics Reprogrammed in a Cellular Model of Friedreich's Ataxia: Frataxin Deficiency Affects Formation of Respiratory Supercomplexes and Down-regulates Both OXPHOS and Glycolysis. (2013) (0)
- Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency (2018) (0)
- CRYSTAL STRUCTURE OF THE DNA REPAIR PROTEIN UVRB (2000) (0)
- Apparently normal DNA repair and transcript expression in the RB885 strain carrying an intronic deletion in the xpc-1 gene (2010) (0)
- DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer (2021) (0)
- Crystal structure of the DNA repair protein UvrB point mutant Y96A revealing a novel fold for domain 2 (2004) (0)
- UV irradiation remodels the specificity landscape of transcription factors (2022) (0)
- A cut above: Discovery of an repair pathway in bacteria (2016) (0)
- Age dependent DNA damage after MPTP treatment in mice (1999) (0)
- Use of reiterative primer extension methodology to map UV-induced photoproducts at the nucleotide level in the laci gene from genomic DNA (1994) (0)
- Mitochondrial studies in NUBPL associated mitochondrial Complex I deficiency in a family with global developmental delays, ataxia, and cerebellar and pons hypoplasia (2015) (0)
- 138 Double strand break repair in human mitochondrial extracts (2010) (0)
- Abstract 946: Mitochondrial division inhibitor 1 (mdivi-1) overcomes cisplatin resistance independent of dynamin-related protein 1 (Drp1). (2013) (0)
- Preface (1994) (0)
- Abstract A65: Combination of a thioxodihydroquinazolinone compound with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential (2018) (0)
- A New Role for UvrB in NER? Single Molecule Imaging of the NER Complex UvrBC-DNA (2012) (0)
- Direct Single Molecule Imaging Reveals Heterogeneity in Nucleotide Excision Repair (2017) (0)
- Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search (2020) (0)
- Gene Networks in the Developing Zebrafish Retina 8. Karis Kosar and Kari Nejak-Bowen. Determining the effects of Wnt signaling in the alleviation of cholestasis via the promotion of hepatocyte transdifferentiation (2020) (0)
- Abstract POSTER-BIOL-1314: Investigating fatty acid beta-oxidation in ovarian cancer cells (2015) (0)
- UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties. (2023) (0)
- Abstract POSTER-THER-1425: Novel small molecules overcoming platinum drug resistance in ovarian cancer cells (2015) (0)
- Genetic Determinants of Oxidant-Induced Nuclear and Mitochondrial DNA Lesions in a Neonatal Inbred Mouse Model of Acute Lung Injury (2014) (0)
- Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Bacillus caldotenax (2005) (0)
- Graphical snapshot of Samuel H. Wilson. (2020) (0)
- Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima (2005) (0)
- CRYSTAL STRUCTURE OF THE DNA REPAIR PROTEIN UVRB IN COMPLEX WITH ATP (2000) (0)
- Inter‐Strain Variation in Mouse Mitochondrial Genome and Effects of Oxidative Stress (2016) (0)
- Staggering in the cleavage pattern of E. coli ABC-excinuclease (1986) (0)
- Abstract 1139: Tumor-associated fibroblasts facilitate head and neck cancer metabolism (2015) (0)
- Abstract P1-03-03: Invasive lobular carcinoma and invasive ductal carcinoma differ in immune response, translation efficiency and metabolic rate (2018) (0)
- Abstract 60: Altering tumor cell metabolism may contribute to the antitumor activity of ethyl pyruvate (2010) (0)
- DNA repair | Nucleotide Excision Repair, Bacterial: The UvrABCD System (2021) (0)
- Abstract A10: Fatty acid synthesis inhibitor, orlistat, potentiates cisplatin-induced toxicity in ovarian cancer cells (2018) (0)
- Abstract B08: HMGB1 regulates natural killer (NK) cell metabolism and cross-talk with dendritic cells (DCs) (2015) (0)
- Announcement: New special Database issue feature for DNA Repair ☆ (2013) (0)
- Abstract 3792: Phenethyl isothiocyanate inhibits oxidative phosphorylation to initiate reactive oxygen species-mediated death of human prostate cancer cells (2010) (0)
- Abstract 5344: Novel thioxodihydroquinazolinone small molecules for combination with platinum drugs to reverse platinum resistance through inducing mitochondrial apoptosis independent of Bax and Bak (2015) (0)
- [Trimethylaminuria: 'Help, my child smells of fish!'] (2018) (0)
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What Schools Are Affiliated With Bennett Van Houten?
Bennett Van Houten is affiliated with the following schools:
