Benoit Coulombe
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Canadian scientist
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Benoit Coulombebiology Degrees
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Molecular Biology
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Genetics
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Biology
Benoit Coulombe's Degrees
- PhD Biochemistry Université de Montréal
- Masters Biochemistry Université de Montréal
- Bachelors Biochemistry Université de Montréal
Why Is Benoit Coulombe Influential?
(Suggest an Edit or Addition)According to Wikipedia, Benoit Coulombe is a Canadian scientist whose research focuses on the mechanisms by which regulated protein–protein, protein–DNA and protein–RNA interactions control the activity of RNA polymerase II, the molecular machine that synthesizes all messenger RNA and some small-nuclear RNA in eukaryotes.
Benoit Coulombe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data (2013) (1234)
- Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (2007) (426)
- Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 (1994) (378)
- USP8 regulates mitophagy by removing K6‐linked ubiquitin conjugates from parkin (2014) (285)
- Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression. (2006) (278)
- LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated (2008) (232)
- Ordered Conformational Changes in Damaged DNA Induced by Nucleotide Excision Repair Factors* (2004) (166)
- A Newly Uncovered Group of Distantly Related Lysine Methyltransferases Preferentially Interact with Molecular Chaperones to Regulate Their Activity (2013) (143)
- DNA Bending and Wrapping around RNA Polymerase: a “Revolutionary” Model Describing Transcriptional Mechanisms (1999) (122)
- Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III (2015) (116)
- Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity. (1991) (109)
- Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum. (2013) (100)
- PReMod: a database of genome-wide mammalian cis-regulatory module predictions (2006) (96)
- Wrapping of promoter DNA around the RNA polymerase II initiation complex induced by TFIIF. (1998) (96)
- The Protein Interaction Network of the Human Transcription Machinery Reveals a Role for the Conserved GTPase RPAP4/GPN1 and Microtubule Assembly in Nuclear Import and Biogenesis of RNA Polymerase II* (2010) (94)
- High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. (2009) (88)
- Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. (2007) (86)
- Mechanism of Promoter Melting by the Xeroderma Pigmentosum Complementation Group B Helicase of Transcription Factor IIH Revealed by Protein-DNA Photo-Cross-Linking (2000) (80)
- Regulation of molecular chaperones through post-translational modifications: decrypting the chaperone code. (2013) (77)
- R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein (2017) (76)
- Structural Perspective on Mutations Affecting the Function of Multisubunit RNA Polymerases (2006) (70)
- RPAP1, a Novel Human RNA Polymerase II-Associated Protein Affinity Purified with Recombinant Wild-Type and Mutated Polymerase Subunits (2004) (70)
- Characterization and expression of a murine gene homologous to human EPA/TIMP: a virus‐induced gene in the mouse. (1987) (69)
- Localization of Subunits of Transcription Factors IIE and IIF Immediately Upstream of the Transcriptional Initiation Site of the Adenovirus Major Late Promoter (*) (1996) (66)
- Photo-Cross-Linking of a Purified Preinitiation Complex Reveals Central Roles for the RNA Polymerase II Mobile Clamp and TFIIE in Initiation Mechanisms (2004) (65)
- Topological localization of the human transcription factors IIA, IIB, TATA box-binding protein, and RNA polymerase II-associated protein 30 on a class II promoter. (1994) (64)
- RAP74 induces promoter contacts by RNA polymerase II upstream and downstream of a DNA bend centered on the TATA box. (1997) (64)
- A Human RNA Polymerase II-containing Complex Associated with Factors Necessary for Spliceosome Assembly* (2002) (55)
- The PAQosome, an R2TP-Based Chaperone for Quaternary Structure Formation. (2018) (53)
- Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy. (2018) (53)
- Recombinant TBP, transcription factor IIB, and RAP30 are sufficient for promoter recognition by mammalian RNA polymerase II. (1992) (52)
- Human Papillomavirus E1 Helicase Interacts with the WD Repeat Protein p80 To Promote Maintenance of the Viral Genome in Keratinocytes (2007) (48)
- Modeling contaminants in AP-MS/MS experiments. (2011) (45)
- Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2 (2013) (44)
- New insights into the biogenesis of nuclear RNA polymerases? (2010) (38)
- Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase (2012) (38)
- Transcription Factor IIS Cooperates with the E3 Ligase UBR5 to Ubiquitinate the CDK9 Subunit of the Positive Transcription Elongation Factor B* (2010) (36)
- Conformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase. (2010) (36)
- Structural and Functional Interactions of Transcription Factor (TF) IIA with TFIIE and TFIIF in Transcription Initiation by RNA Polymerase II* (2001) (36)
- Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin. (2014) (36)
- Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription. (2008) (36)
- Presence of transcription regulatory elements within an intron of the virus-inducible murine TIMP gene (1988) (34)
- Faculty Opinions recommendation of The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. (2007) (32)
- Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 (2019) (29)
- Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation (2017) (28)
- Interaction Networks of the Molecular Machines That Decode, Replicate, and Maintain the Integrity of the Human Genome * (2004) (28)
- Interactions of a DNA-bound Transcriptional Activator with the TBP-TFIIA-TFIIB-Promoter Quaternary Complex* (2003) (28)
- Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor). (2019) (26)
- Interaction of RNA Polymerase II Fork Loop 2 with Downstream Non-template DNA Regulates Transcription Elongation* (2011) (26)
- In vitro synthesis of the active tissue inhibitor of metalloproteinases encoded by a complementary DNA from virus-infected murine fibroblasts. (1988) (25)
- Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry. (2013) (24)
- Upstream ORF-encoded ASDURF is a novel prefoldin-like subunit of the PAQosome. (2019) (23)
- The RPB2 Flap Loop of Human RNA Polymerase II Is Dispensable for Transcription Initiation and Elongation (2011) (23)
- A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA-SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts. (2015) (23)
- Binding sites between palladium(II) and nucleosides or nucleotides and crystal structure of [Pd(diethylenetriamine)(guanosine)](ClO4)2 (1980) (21)
- Identification of three mammalian proteins that bind to the yeast TATA box protein TFIID. (1992) (19)
- The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis (2019) (19)
- Detection of Locally Over-Represented GO Terms in Protein-Protein Interaction Networks (2009) (17)
- Topological Localization of the Carboxyl-Terminal Domain of RNA Polymerase II in the Initiation Complex* (1999) (17)
- Expression of intracellular interferon constitutively activates ISGF3 and confers resistance to EMC viral infection. (1996) (17)
- Basal expression of the gene (TIMP) encoding the murine tissue inhibitor of metalloproteinases is mediated through AP1- and CCAAT-binding factors. (1992) (15)
- Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II. (2010) (15)
- Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals. (2014) (15)
- The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II (2005) (14)
- DNA wrapping in transcription initiation by RNA polymerase II. (1999) (12)
- De novo variants in POLR3B cause ataxia, spasticity, and demyelinating neuropathy. (2021) (11)
- Regulation of interferon gene expression: mechanism of action of the If-1 locus (1988) (10)
- Mapping the disease protein interactome: toward a molecular medicine GPS to accelerate drug and biomarker discovery. (2011) (10)
- Posttranslational modification of proprotein convertase subtilisin/kexin type 9 is differentially regulated in response to distinct cardiometabolic treatments as revealed by targeted proteomics. (2018) (10)
- Discovery of Antivirals Using Phage Display (2021) (9)
- Use of site-specific protein-DNA photocrosslinking to analyze the molecular organization of the RNA polymerase II initiation complex. (2001) (8)
- Functional 5′ UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks (2017) (8)
- Faculty Opinions recommendation of Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses. (2020) (7)
- How do our cells build their protein interactome? (2018) (7)
- Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci (2022) (7)
- Interactome Analysis of KIN (Kin17) Shows New Functions of This Protein (2021) (5)
- Role of the PAQosome in Regulating Arrangement of Protein Quaternary Structure in Health and Disease. (2018) (5)
- Steps towards a repertoire of comprehensive maps of human protein interaction networks: the Human Proteotheque Initiative (HuPI). (2008) (5)
- Functional dissection of the catalytic mechanism of mammalian RNA polymerase II. (2005) (5)
- Abnormal expression of RNA polymerase II‐associated proteins in muscle of patients with myofibrillar myopathies (2015) (5)
- Faculty Opinions recommendation of Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans. (2020) (4)
- Expression of a synthetic human interferon-alpha 1 gene with modified nucleotide sequence in mammalian cells. (1986) (4)
- Site-specific protein-DNA photocross-linking of purified complexes: topology of the RNA polymerase II transcription initiation complex. (2003) (4)
- Defining protein interactions that regulate disease progression. (2009) (4)
- Analysis of the SARS-CoV-2-host protein interaction network reveals new biology and drug candidates: focus on the spike surface glycoprotein and RNA polymerase (2021) (4)
- POLR3-related leukodystrophy: How do mutations affecting RNA polymerase III subunits cause hypomyelination? (2021) (3)
- Defining protein interactions that regulate disease progression (2009) (3)
- Faculty Opinions recommendation of Structure of the RNA-dependent RNA polymerase from COVID-19 virus. (2020) (2)
- Faculty Opinions recommendation of Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency. (2020) (2)
- Faculty Opinions recommendation of SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. (2020) (2)
- Inhibitors of Multisubunit RNA Polymerases as Tools to Study Transcriptional Mechanisms in Prokaryotes and Eukaryotes (2008) (2)
- The unphosphorylated form of the PAQosome core subunit RPAP3 binds ribosomal preassembly complexes to modulate ribosome biogenesis (2021) (2)
- Use of site-specific protein-DNA photocrosslinking of purified complexes to analyze the topology of the RNA polymerase II transcription initiation complex. (2009) (2)
- Variants in LSM7 impair LSM complexes assembly, neurodevelopment in zebrafish and may be associated with an ultra-rare neurological disease (2021) (2)
- Faculty Opinions recommendation of Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants. (2020) (2)
- Proteomic Analysis Reveals a Role for the GTPase RPAP4/GPN1 and the Cochaperone RPAP3 in Biogenesis of All Three Nuclear RNA Polymerases (2014) (2)
- Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia (2022) (1)
- Biallelic pathogenic variants in LSM7 impair assembly of LSM complexes, impairs neurodevelopment in zebrafish and may be associated with an ultra rare neurodevelopmental and neurodegenerative disorder (2021) (1)
- A NETWORK OF PROTEIN COMPLEXES SIGNALING TO THE RNA POLYMERASE II TRANSCRIPTION APPARATUS IN HUMAN CELLS (2006) (1)
- Nuclear import of RNA polymerase II requires the conserved GPN‐loop GTPase XAB1/GPN1 (2010) (1)
- Faculty Opinions recommendation of Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. (2004) (1)
- Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H (2022) (1)
- Faculty Opinions recommendation of Search-and-replace genome editing without double-strand breaks or donor DNA. (2020) (1)
- Faculty Opinions recommendation of Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. (2007) (1)
- ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia (2022) (1)
- Faculty Opinions recommendation of Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. (2020) (1)
- Faculty Opinions recommendation of Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. (2020) (1)
- Faculty Opinions recommendation of Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. (2020) (0)
- Faculty Opinions recommendation of NTP-driven translocation by human RNA polymerase II. (2003) (0)
- Faculty Opinions recommendation of Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin. (2021) (0)
- Faculty Opinions recommendation of SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling. (2020) (0)
- Late abstracts 186–187 (2005) (0)
- Faculty Opinions recommendation of Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates. (2020) (0)
- Faculty Opinions recommendation of A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. (2021) (0)
- Faculty Opinions recommendation of Nature's 10: ten people who helped shape science in 2020. (2020) (0)
- Faculty Opinions recommendation of Crystal structure of a transcription factor IIIB core interface ternary complex. (2003) (0)
- Faculty Opinions recommendation of Lessons from the host defences of bats, a unique viral reservoir. (2021) (0)
- Faculty Opinions recommendation of 'The long tail of COVID-19' - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients. (2021) (0)
- Faculty Opinions recommendation of Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum. (2020) (0)
- Faculty Opinions recommendation of Spike mutation D614G alters SARS-CoV-2 fitness. (2020) (0)
- [Focus on RNA polymerase II]. (2002) (0)
- Faculty Opinions recommendation of Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection. (2020) (0)
- Faculty Opinions recommendation of COVID-19 testing: One size does not fit all. (2021) (0)
- Faculty Opinions recommendation of A core promoter element downstream of the TATA box that is recognized by TFIIB. (2005) (0)
- Pdgfrα-dependent Polr3b Exon Loss Recapitulates POLR3-related Hypomyelinating Leukodystrophy Phenotypes in vivo (S2.004) (2023) (0)
- Faculty Opinions recommendation of Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. (2020) (0)
- Faculty Opinions recommendation of Infectivity of asymptomatic versus symptomatic COVID-19. (2020) (0)
- Faculty Opinions recommendation of Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome. (2021) (0)
- Faculty Opinions recommendation of The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation. (2020) (0)
- Faculty Opinions recommendation of Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report. (2020) (0)
- Faculty Opinions recommendation of Could COVID delirium bring on dementia? (2020) (0)
- Faculty Opinions recommendation of Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer. (2020) (0)
- Faculty Opinions recommendation of KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs. (2020) (0)
- Faculty Opinions recommendation of Single-Cell Proteomics: Progress and Prospects. (2020) (0)
- How do our cells build their protein interactome? (2018) (0)
- Faculty Opinions recommendation of 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. (2021) (0)
- Faculty Opinions recommendation of Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. (2020) (0)
- An Analytic Formula for the Delta of Variance Swap (2008) (0)
- Faculty Opinions recommendation of The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing assembly of virus-like particles. (2020) (0)
- Faculty Opinions recommendation of Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. (2020) (0)
- Faculty Opinions recommendation of Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. (2020) (0)
- Faculty Opinions recommendation of Closing and opening of the RNA polymerase trigger loop. (2020) (0)
- Faculty Opinions recommendation of QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis. (2021) (0)
- Faculty Opinions recommendation of White matter injury in the preterm infant: pathology and mechanisms. (2021) (0)
- De novo variants in POLR3B cause ataxia, spasticity, and demyelinating neuropathy. (2022) (0)
- Mapping the human interactome: Why is a coordinated international effort both essential and timely? (2010) (0)
- Faculty Opinions recommendation of SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication. (2020) (0)
- Faculty Opinions recommendation of β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. (2020) (0)
- Regulation ofInterferon GeneExpression: Mechanism ofAction oftheIf-i Locus (1988) (0)
- Faculty Opinions recommendation of Structural and molecular interrogation of intact biological systems. (2020) (0)
- Faculty Opinions recommendation of Alternative transcription cycle for bacterial RNA polymerase. (2020) (0)
- Faculty Opinions recommendation of The major genetic risk factor for severe COVID-19 is inherited from Neanderthals. (2020) (0)
- Faculty Opinions recommendation of Gene duplication and neofunctionalization: POLR3G and POLR3GL. (2021) (0)
- Faculty Opinions recommendation of Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. (2020) (0)
- Faculty Opinions recommendation of The 2021 Nucleic Acids Research database issue and the online molecular biology database collection. (2021) (0)
- Faculty Opinions recommendation of CRISPR artificial splicing factors. (2020) (0)
- Faculty Opinions recommendation of TTC5 mediates autoregulation of tubulin via mRNA degradation. (2020) (0)
- Introduction for the Special Issue of METHODS on Detection and quantification of proteins in clinical samples by mass spectrometry. (2015) (0)
- Faculty Opinions recommendation of Toward superhuman SARS-CoV-2 immunity? (2020) (0)
- Faculty Opinions recommendation of What's your risk of catching COVID? These tools help you to find out. (2020) (0)
- Faculty Opinions recommendation of Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate. (2020) (0)
- Faculty Opinions recommendation of Structural basis of RNA polymerase III transcription initiation. (2021) (0)
- Faculty Opinions recommendation of Fast-spreading COVID variant can elude immune responses. (2021) (0)
- Faculty Opinions recommendation of The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior. (2020) (0)
- Faculty Opinions recommendation of Changes in the oligodendrocyte progenitor cell proteome with ageing. (2020) (0)
- Faculty Opinions recommendation of Donation of catalytic residues to RNA polymerase active center by transcription factor Gre. (2004) (0)
- Faculty Opinions recommendation of How COVID vaccines are being divvied up around the world. (2020) (0)
- The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis (2019) (0)
- Faculty Opinions recommendation of Comprehensive analysis of TCR repertoire in COVID-19 using single cell sequencing. (2021) (0)
- Faculty Opinions recommendation of Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells. (2020) (0)
- Faculty Opinions recommendation of Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. (2020) (0)
- Faculty Opinions recommendation of Mutation in POLR3K causes hypomyelinating leukodystrophy and abnormal ribosomal RNA regulation. (2021) (0)
- Faculty Opinions recommendation of SARS-CoV-2 viral load is associated with increased disease severity and mortality. (2020) (0)
- Faculty Opinions recommendation of Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. (2020) (0)
- Faculty Opinions recommendation of De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2. (2020) (0)
- Faculty Opinions recommendation of Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia. (2021) (0)
- A new family of lysine methyltransferases preferentially targets molecular chaperones to orchestrate the functional organization of the human proteome (555.12) (2014) (0)
- Faculty Opinions recommendation of The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS. (2020) (0)
- Faculty Opinions recommendation of Nucleolar RNA polymerase II drives ribosome biogenesis. (2020) (0)
- Faculty Opinions recommendation of Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome. (2021) (0)
- Faculty Opinions recommendation of Dynamic changes in anti-SARS-CoV-2 antibodies during SARS-CoV-2 infection and recovery from COVID-19. (2020) (0)
- Faculty Opinions recommendation of The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins. (2020) (0)
- Faculty Opinions recommendation of LifeTime and improving European healthcare through cell-based interceptive medicine. (2020) (0)
- Faculty Opinions recommendation of Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations. (2020) (0)
- Faculty Opinions recommendation of Spatiotemporal dissection of the cell cycle with single-cell proteogenomics. (0)
- Faculty Opinions recommendation of Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. (2020) (0)
- High‐precision mapping of the protein interaction network for the human transcription machinery reveals a novel class of cellular regulatory factors (2008) (0)
- Faculty Opinions recommendation of Translational reprogramming marks adaptation to asparagine restriction in cancer. (2020) (0)
- Faculty Opinions recommendation of Visualizing RNA extrusion and DNA wrapping in transcription elongation complexes of bacterial and eukaryotic RNA polymerases. (2003) (0)
- Faculty Opinions recommendation of Effective control of SARS-CoV-2 transmission in Wanzhou, China. (2020) (0)
- Faculty Opinions recommendation of Face masks considerably reduce COVID-19 cases in Germany. (2020) (0)
- Faculty Opinions recommendation of Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2's main protease. (2020) (0)
- Faculty Opinions recommendation of SARS-CoV-2 infection induces beta cell transdifferentiation. (2021) (0)
- Faculty Opinions recommendation of Longitudinal symptom dynamics of COVID-19 infection. (2020) (0)
- Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation (2017) (0)
- Faculty Opinions recommendation of Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse. (2021) (0)
- Structure and function of murine TIMP gene. (1992) (0)
- Molecular organization of RNA polymerase II transcription complexes (1999) (0)
- Faculty Opinions recommendation of Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. (2005) (0)
- Faculty Opinions recommendation of A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. (2020) (0)
- Faculty Opinions recommendation of Gene expression cartography. (2021) (0)
- Faculty Opinions recommendation of Stepwise promoter melting by bacterial RNA polymerase. (2020) (0)
- Faculty Opinions recommendation of Biallelic variants in POLR3GL cause endosteal hyperostosis and oligodontia. (2021) (0)
- Faculty Opinions recommendation of The UK has approved a COVID vaccine - here's what scientists now want to know. (2020) (0)
- Faculty Opinions recommendation of Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. (2020) (0)
- Faculty Opinions recommendation of The proteome landscape of the kingdoms of life. (2020) (0)
- Faculty Opinions recommendation of Tracing tumorigenesis in a solid tumor model at single-cell resolution. (2021) (0)
- Faculty Opinions recommendation of Evidence for dynamically organized modularity in the yeast protein-protein interaction network. (2004) (0)
- Faculty Opinions recommendation of Cerebellar hypoplasia with endosteal sclerosis is a POLR3-related disorder. (2021) (0)
- A Web Resource for Improved Analysis of AP-MS Protein Interaction Data. (2013) (0)
- The PAQosome, a novel molecular chaperoning machine for assembly of human protein complexes and networks (2020) (0)
- Characterization of the dynamic interaction network for human RNA polymerase II in health and disease (2013) (0)
- Faculty Opinions recommendation of RNA polymerase III subunit POLR3G regulates specific subsets of polya+ and smallrna transcriptomes and splicing in human pluripotent stem cells. (2021) (0)
- Faculty Opinions recommendation of Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. (2021) (0)
- Faculty Opinions recommendation of Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. (2020) (0)
- Binding sites betweell palladium(I1) and nucleosides or nucledtides and crystal structure sf (Pd(diethylenetriamine)(gui~nssine))(CPO~)~ (1980) (0)
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