Berislav V. Zloković
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Berislav V. Zlokovićbiology Degrees
Biology
#3868
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#5857
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Neuroscience
#381
World Rank
#398
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Biology
Berislav V. Zloković's Degrees
- PhD Biochemistry University of Belgrade
- Doctorate Medicine University of Belgrade
Why Is Berislav V. Zloković Influential?
(Suggest an Edit or Addition)Berislav V. Zloković's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders (2008) (2758)
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders (2011) (2146)
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders (2018) (1329)
- Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. (2000) (1322)
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus (2015) (1289)
- RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain (2003) (1274)
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging (2010) (1179)
- Apolipoprotein E controls cerebrovascular integrity via cyclophilin A (2012) (993)
- Establishment and Dysfunction of the Blood-Brain Barrier (2015) (954)
- Blood-Brain Barrier: From Physiology to Disease and Back. (2019) (910)
- Neurovascular mechanisms of Alzheimer's neurodegeneration (2005) (897)
- Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease (2009) (802)
- Central nervous system pericytes in health and disease (2011) (790)
- The cytoprotective protein C pathway. (2007) (758)
- Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction (2018) (758)
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease (2017) (692)
- LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms (2004) (681)
- apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. (2008) (667)
- Pericytes of the neurovascular unit: key functions and signaling pathways (2016) (651)
- Clearance systems in the brain—implications for Alzheimer disease (2015) (632)
- Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous System (2007) (626)
- P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. (2005) (595)
- Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective (2003) (588)
- APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline (2020) (507)
- Pericyte loss influences Alzheimer-like neurodegeneration in mice (2013) (495)
- Vascular contributions to cognitive impairment and dementia including Alzheimer's disease (2015) (478)
- A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. (2012) (475)
- The role of brain vasculature in neurodegenerative disorders (2018) (473)
- GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration (2015) (435)
- Clearance systems in the brain-implications for Alzheimer disease. (2015) (434)
- Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. (1996) (429)
- Clearance of amyloid-β peptide across the blood-brain barrier: Implication for therapies in Alzheimer’s disease (2009) (427)
- LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms. (2004) (423)
- Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease (2016) (411)
- ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration (2008) (410)
- RAGE (Yin) Versus LRP (Yang) Balance Regulates Alzheimer Amyloid &bgr;-Peptide Clearance Through Transport Across the Blood–Brain Barrier (2004) (399)
- Alzheimer’s disease: A matter of blood–brain barrier dysfunction? (2017) (385)
- Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy. (2016) (385)
- Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in Alzheimer's Disease (2013) (380)
- Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons (2018) (368)
- Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease. (2016) (366)
- Vascular dysfunction—The disregarded partner of Alzheimer's disease (2019) (361)
- Clearance of amyloid-β by circulating lipoprotein receptors (2007) (356)
- Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease. (2007) (350)
- Clearing amyloid through the blood–brain barrier (2004) (348)
- Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain (2017) (341)
- Central role for PICALM in amyloid–β blood–brain barrier transcytosis and clearance (2015) (327)
- Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor* (2004) (324)
- Perivascular spaces in the brain: anatomy, physiology and pathology (2020) (283)
- Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease (2005) (276)
- Preferential Susceptibility of Brain Tumors to the Antiangiogenic Effects of an &agr;v Integrin Antagonist (2001) (270)
- Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling (2010) (264)
- Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3 (2004) (264)
- Apolipoprotein J (clusterin) and Alzheimer's disease (2000) (256)
- Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides. (2000) (255)
- Pericyte degeneration causes white matter dysfunction in the mouse central nervous system (2018) (254)
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis (2012) (253)
- Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. (1998) (248)
- Activated protein C inhibits tissue plasminogen activator–induced brain hemorrhage (2006) (248)
- SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells (2009) (242)
- IgG-Assisted Age-Dependent Clearance of Alzheimer's Amyloid β Peptide by the Blood–Brain Barrier Neonatal Fc Receptor (2005) (238)
- Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease. (2009) (234)
- Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease. (2013) (230)
- Coupling of Angiogenesis and Neurogenesis in Cultured Endothelial Cells and Neural Progenitor Cells after Stroke (2008) (228)
- Clearance of amyloid-beta by circulating lipoprotein receptors. (2007) (220)
- Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain (2010) (217)
- Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C (2004) (215)
- beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1. (2000) (205)
- The Pericyte: A Forgotten Cell Type with Important Implications for Alzheimer's Disease? (2014) (203)
- Anti-Inflammatory, Antithrombotic, and Neuroprotective Effects of Activated Protein C in a Murine Model of Focal Ischemic Stroke (2001) (203)
- Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss (2019) (201)
- Activated protein C: biased for translation. (2015) (194)
- Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease. (2012) (193)
- Hypertension Induces Brain &bgr;-Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature (2012) (193)
- Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype (2007) (192)
- Circulating Antibody against Tumor Necrosis Factor–Alpha Protects Rat Brain from Reperfusion Injury (1998) (191)
- Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice (2014) (179)
- Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. (2009) (176)
- Neurodegeneration and the neurovascular unit (2010) (174)
- Differential regulation of leptin transport by the choroid plexus and blood-brain barrier and high affinity transport systems for entry into hypothalamus and across the blood-cerebrospinal fluid barrier. (2000) (173)
- Understanding the role of the perivascular space in cerebral small vessel disease (2018) (168)
- Consensus statement for diagnosis of subcortical small vessel disease (2016) (163)
- Blood–spinal cord barrier pericyte reductions contribute to increased capillary permeability (2012) (162)
- The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease. (2008) (162)
- Blood-Brain Barrier Transport of Circulating Alzheimer′s Amyloid β (1993) (158)
- Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier. (1996) (155)
- Brain imaging of neurovascular dysfunction in Alzheimer’s disease (2016) (154)
- Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1 (2015) (152)
- Measurement of Solute Transport Across the Blood–Brain Barrier in the Perfused Guinea Pig Brain: Method and Application to N‐Methyl‐α‐Aminoisobutyric Acid (1986) (152)
- Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta. (1994) (150)
- Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease. (2012) (150)
- Isoform‐Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood‐Brain Barrier Transport of Circulating Alzheimer's Amyloid β (1997) (147)
- Two‐Photon Imaging of Astrocytic Ca2+ Signaling and the Microvasculature in Experimental Mice Models of Alzheimer's Disease (2007) (142)
- Cerebrovascular Accumulation and Increased Blood‐Brain Barrier Permeability to Circulating Alzheimer's Amyloid β Peptide in Aged Squirrel Monkey with Cerebral Amyloid Angiopathy (1998) (139)
- New therapeutic targets in the neurovascular pathway in Alzheimer’s disease (2008) (138)
- Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions. (2002) (135)
- Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis (2012) (131)
- Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism (2018) (129)
- Cytoprotective protein C pathways and implications for stroke and neurological disorders (2011) (129)
- Permeability of the Blood‐Brain Barrier to the Immunosuppressive Cyclic Peptide Cyclosporin A (1990) (129)
- Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background. (1999) (127)
- Clearance of amyloid β-peptide from brain: transport or metabolism? (2000) (126)
- Transport of Leucine‐Enkephalin Across the Blood‐Brain Barrier in the Perfused Guinea Pig Brain (1987) (121)
- Chronic Nicotine Treatment Enhances Focal Ischemic Brain Injury and Depletes Free Pool of Brain Microvascular Tissue Plasminogen Activator in Rats (1997) (120)
- Myocardin Is Sufficient for a Smooth Muscle–Like Contractile Phenotype (2008) (119)
- A simple method for isolation and characterization of mouse brain microvascular endothelial cells (2003) (118)
- Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. (2003) (116)
- Cellular and Molecular Neurosurgery: Pathways from Concept to Reality-Part II: Vector Systems and Delivery Methodologies for Gene Therapy of the Central Nervous System. (1997) (114)
- Protein C anticoagulant and cytoprotective pathways (2012) (113)
- Blood-brain barrier permeability to leucine-enkephalin,d-Alanine2-d-leucine5-enkephalin and their N-terminal amino acid (tyrosine) (1985) (111)
- Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. (2010) (108)
- Substitution at codon 22 reduces clearance of Alzheimer’s amyloid-β peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood (2002) (106)
- Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin‐bound and free iron into the rat brain (2004) (105)
- Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus. (1993) (103)
- Neurovascular Pathways and Alzheimer Amyloid β‐peptide (2005) (103)
- Kinetics of arginine-vasopressin uptake at the blood-brain barrier. (1990) (100)
- Activated Protein C Promotes Neovascularization and Neurogenesis in Postischemic Brain via Protease-Activated Receptor 1 (2008) (98)
- Cerebrovascular Permeability to Peptides: Manipulations of Transport Systems at the Blood-Brain Barrier (1995) (96)
- Recommendations of the Alzheimer's Disease–Related Dementias Conference (2014) (95)
- Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities. (2012) (95)
- Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium. (2002) (93)
- Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone (1985) (91)
- Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown. (2013) (91)
- Functional and structural properties of lipid-associated apolipoprotein J (clusterin). (1999) (90)
- Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity (2009) (90)
- Brain Clearance of Alzheimer's Amyloid-β40 in the Squirrel Monkey: A SPECT Study in a Primate Model of Cerebral Amyloid Angiopathy (2002) (89)
- Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood–brain barrier permeability using dynamic contrast‐enhanced MRI (2016) (88)
- Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease (2015) (86)
- Kinetic Analysis of Leucine‐Enkephalin Cellular Uptake at the Luminal Side of the Blood‐Brain Barrier of an In Situ Perfused Guinea‐Pig Brain (1989) (85)
- Shedding of soluble platelet-derived growth factor receptor-β from human brain pericytes (2015) (85)
- Activated protein C, protease activated receptor 1, and neuroprotection. (2018) (84)
- Evidence for a lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: kinetics of unidirectional influx, carrier specificity and effects of glucagon. (1985) (82)
- Slow Penetration of Thyrotropin‐Releasing Hormone Across the Blood‐Brain Barrier of an In Situ Perfused Guinea Pig Brain (1988) (81)
- Protein S Confers Neuronal Protection During Ischemic/Hypoxic Injury in Mice (2003) (81)
- The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's disease. (2002) (80)
- Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model. (2003) (79)
- Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs (1996) (79)
- Glycoprotein 330/Megalin (LRP-2) Has Low Prevalence as mRNA and Protein in Brain Microvessels and Choroid Plexus (1999) (76)
- Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling (2017) (74)
- Blood-Brain Barrier Permeability and Gadolinium: Benefits and Potential Pitfalls in Research. (2016) (73)
- Evidence for the Existence of a Sodium-dependent Glutathione (GSH) Transporter (1996) (70)
- Functional recovery after embolic stroke in rodents by activated protein C (2005) (70)
- Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop (2020) (70)
- 3K3A–activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice (2016) (69)
- An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents (2012) (69)
- Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes. (2004) (68)
- Endothelial Protein C Receptor-Assisted Transport of Activated Protein C across the Mouse Blood—Brain Barrier (2009) (67)
- Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures (2001) (65)
- Role of clusterin in the brain vascular clearance of amyloid-β (2017) (65)
- A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig (1990) (64)
- Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide. (2000) (64)
- Blood-brain barrier transport of circulating Alzheimer's amyloid beta. (1993) (63)
- Evidence for transcapillary transport of reduced glutathione in vascular perfused guinea-pig brain. (1994) (63)
- Clearance of amyloid beta-peptide from brain: transport or metabolism? (2000) (62)
- Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's disease. (2011) (61)
- PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke. (2018) (61)
- Activated Protein C is Neuroprotective and Mediates New Blood Vessel Formation and Neurogenesis After Controlled Cortical Impact (2010) (61)
- Cellular and Molecular Neurosurgery: Pathways from Concept to Reality-Part I: Target Disorders and Concept Approaches to Gene Therapy of the Central Nervous System. (1997) (61)
- Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity. (2009) (60)
- Vascular disorder in Alzheimer's disease: role in pathogenesis of dementia and therapeutic targets. (2002) (60)
- A single-cell atlas of the normal and malformed human brain vasculature (2022) (59)
- Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9 (2014) (59)
- Kinetics and Na independence of amino acid uptake by blood side of perfused sheep choroid plexus. (1990) (58)
- Remodeling after stroke (2006) (58)
- Method for measurement of the blood–brain barrier permeability in the perfused mouse brain: application to amyloid-β peptide in wild type and Alzheimer’s Tg2576 mice (2004) (57)
- “Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop (2016) (57)
- ROCKETSHIP: a flexible and modular software tool for the planning, processing and analysis of dynamic MRI studies (2015) (57)
- Outwitting the Blood-Brain Barrier for Therapeutic Purposes: Osmotic Opening and Other Means (1998) (56)
- Protein S Protects Neurons from Excitotoxic Injury by Activating the TAM Receptor Tyro3–Phosphatidylinositol 3-Kinase–Akt Pathway through Its Sex Hormone-Binding Globulin-Like Region (2010) (56)
- Preclinical safety and pharmacokinetic profile of 3K3A-APC, a novel, modified activated protein C for ischemic stroke. (2012) (55)
- Activated Protein C Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats (2013) (55)
- An Activated Protein C Analog Stimulates Neuronal Production by Human Neural Progenitor Cells via a PAR1-PAR3-S1PR1-Akt Pathway (2013) (54)
- Expression of tissue plasminogen activator in cerebral capillaries: possible fibrinolytic function of the blood-brain barrier. (1995) (54)
- Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial (2020) (53)
- Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood–brain barrier permeability in the corpus callosum (2015) (53)
- Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis (2021) (52)
- Methamphetamine causes sustained depression in cerebral blood flow (2011) (52)
- The promise of protein C. (2006) (51)
- Cytoprotective-selective activated protein C therapy for ischaemic stroke (2014) (51)
- Detection of brain tumor invasion and micrometastasis in vivo by expression of enhanced green fluorescent protein. (1998) (49)
- Brain capillary tissue plasminogen activator in a diabetes stroke model. (1996) (49)
- Strategies to circumvent vascular barriers of the central nervous system. (1998) (48)
- Remote control of BBB: A tale of exosomes and microRNA (2017) (46)
- Activated protein C and ischemic stroke (2004) (45)
- Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA) (2020) (45)
- Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo (2020) (44)
- APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β (2021) (44)
- Impaired spine formation and learning in GPCR kinase 2 interacting protein-1 (GIT1) knockout mice (2010) (43)
- Transport of circulating reduced glutathione at the basolateral side of the anterior lens epithelium: physiologic importance and manipulations. (1996) (42)
- 3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice (2019) (42)
- In vivo imaging and analysis of cerebrovascular hemodynamic responses and tissue oxygenation in the mouse brain (2018) (41)
- Acute Ablation of Cortical Pericytes Leads to Rapid Neurovascular Uncoupling (2020) (41)
- Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier (1992) (41)
- Neutral amino acid uptake by the isolated perfused sheep choroid plexus. (1989) (40)
- Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A (2021) (39)
- Blood-brain barrier permeability to dipeptides and their constituent amino acids (1983) (39)
- Associations between Vascular Function and Tau PET Are Associated with Global Cognition and Amyloid (2020) (39)
- Intravenous RMP-7 increases delivery of ganciclovir into rat brain tumors and enhances the effects of herpes simplex virus thymidine kinase gene therapy. (1998) (39)
- A Lipoprotein Receptor Cluster IV Mutant Preferentially Binds Amyloid-β and Regulates Its Clearance from the Mouse Brain* (2013) (38)
- Can Blood–Brain Barrier Play a Role in the Development of Cerebral Amyloidosis and Alzheimer's Disease Pathology (1997) (38)
- Thrombomodulin expression in bovine brain capillaries. Anticoagulant function of the blood-brain barrier, regional differences, and regulatory mechanisms. (1997) (37)
- Endovascular Restorative Neurosurgery: A Novel Concept for Molecular and Cellular Therapy of the Nervous System (2003) (36)
- Activated protein C analog with reduced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact (2010) (36)
- Molecular characterization of a reduced glutathione transporter in the lens. (1995) (36)
- Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model. (1997) (36)
- Cereport™ (RMP-7) Increases the Permeability of Human Brain Microvascular Endothelial Cell Monolayers1 (1999) (34)
- Saturable mechanism for delta sleep-inducing peptide (DSIP) at the blood-brain barrier of the vascularly perfused guinea pig brain (1989) (34)
- The Blood-Brain Barrier, Amino Acids and Peptides (1990) (34)
- Identification of a novel, sodium-dependent, reduced glutathione transporter in the rat lens epithelium. (1996) (34)
- TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotectionupon Ischemic Stroke in Mice (2019) (34)
- Blood-Brain Barrier: A Dual Life of MFSD2A? (2014) (33)
- A simple technique to determine glutathione (GSH) levels and synthesis in ocular tissues as GSH-bimane adduct: application to normal and galactosemic guinea-pigs. (1993) (32)
- Neurovascular Unit: Basic and Clinical Imaging with Emphasis on Advantages of Ferumoxytol (2018) (32)
- The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier A β Clearance in Alzheimer’s Disease (2010) (31)
- Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway (2011) (31)
- A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid (2020) (31)
- Species‐dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity (2009) (31)
- Unidirectional uptake of enkephalins at the blood-tissue interface of the blood-cerebrospinal fluid barrier: a saturable mechanism (1988) (31)
- An Introduction to the Blood-Brain Barrier (1992) (31)
- Hypertension & Cognitive Impairment Hypertension Induces Brain -Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature (2012) (30)
- Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. (1989) (29)
- Vascular plasticity and cognition during normal aging and dementia. (2015) (29)
- Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons. (2019) (29)
- Pericyte constriction after stroke: the jury is still out (2010) (29)
- Nicotine Downregulates α2 Isoform of Na,K-ATPase at the Blood-Brain Barrier and Brain in Rats (1994) (29)
- Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1 (2013) (28)
- Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline (2020) (28)
- Passage of delta sleep-inducing peptide (DSIP) across the blood-cerebrospinal fluid barrier (1988) (28)
- Erratum: Clearance systems in the brain—implications for Alzheimer diseaser (2016) (28)
- Circulating neuroactive peptides and the blood-brain and blood-cerebrospinal fluid barriers. (1990) (28)
- Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. (2019) (27)
- Electroencephalographic Characteristics of Audiogenic Seizures Induced in Metaphit‐Treated Small Rodents (1991) (27)
- Mechanism of amyloid peptide induced CCR5 expression in monocytes and its inhibition by siRNA for Egr-1. (2005) (27)
- Exogenous microglia enter the brain and migrate into ischaemic hippocampal lesions (1999) (27)
- 2016 Scientific Sessions Sol Sherry Distinguished Lecturer in Thrombosis: Thrombotic Stroke: Neuroprotective Therapy by Recombinant-Activated Protein C. (2016) (27)
- Neuropeptide transport mechanisms in the central nervous system (1988) (27)
- Cellular and molecular neurosurgery: pathways from concept to reality--part I: target disorders and concept approaches to gene therapy of the central nervous system. (1997) (26)
- Immunohistochemical localization of tissue plasminogen activator in vascular endothelium of stroke-prone regions of the rat brain. (1998) (26)
- Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid beta in guinea pigs. (1996) (26)
- Activated protein C promotes neuroprotection: mechanisms and translation to the clinic. (2016) (25)
- From the liver to the blood–brain barrier: An interconnected system regulating brain amyloid‐β levels (2011) (24)
- Cellular uptake and transport of methylprednisolone at the blood-brain barrier. (1996) (24)
- Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort (2020) (24)
- Transport-Clearance Hypothesis for Alzheimer's Disease and Potential Therapeutic Implications (2013) (24)
- Endothelial cell protein C receptor: role beyond endothelium? (2007) (23)
- Lack of Smad or Notch leads to a fatal game of brain pericyte hopscotch. (2011) (23)
- Brain Injury and Cerebrovascular Fibrin Deposition Correlate with Reduced Antithrombotic Brain Capillary Functions in a Hypertensive Stroke Model (2000) (22)
- Species-specific anticoagulant and mitogenic activities of murine protein S (2009) (21)
- Blood-to-lens transport of reduced glutathione in an in situ perfused guinea-pig eye. (1994) (21)
- Antithrombotic, procoagulant, and fibrinolytic mechanisms in cerebral circulation: implications for brain injury and protection. (1997) (21)
- A lymphatic waste-disposal system implicated in Alzheimer’s disease (2018) (21)
- Kinetics of circulating vasopressin uptake by choroid plexus. (1991) (21)
- In vivo approaches for studying peptide interactions at the blood — brain barrier (1990) (20)
- Combined neurothrombectomy or thrombolysis with adjunctive delivery of 3K3A-activated protein C in acute ischemic stroke (2015) (20)
- Chronic amphetamine intoxication and the blood-brain barrier permeability to inert polar molecules studied in the vascularly perfused guinea pig brain (1989) (19)
- Blood–brain barrier link to human cognitive impairment and Alzheimer’s disease (2022) (19)
- Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease (2020) (18)
- Permeability imaging as a predictor of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage (2018) (18)
- Metaphit‐Induced Audiogenic Seizures in Mice: II. Studies on N‐Methyl‐d‐Aspartic Acid, GABA, and Sodium Channel Receptors and on the Disposition of Metaphit in the Brain (1993) (17)
- Metaphit‐Induced Audiogenic Seizures in Mice: I. Pharmacologic Characterization (1993) (17)
- Galactose-induced cataract formation in guinea pigs: morphologic changes and accumulation of galactitol. (1994) (17)
- Lower cognitive performance of older football players possessing apolipoprotein E epsilon4. (2001) (17)
- Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment (2019) (16)
- Functional connectivity among brain regions affected in Alzheimer’s disease is associated with CSF TNF-α in APOE4 carriers (2019) (16)
- Small molecule inhibition of PIKFYVE kinase rescues gain- and loss-of-function C9ORF72 ALS/FTD disease processes in vivo (2019) (16)
- Role of A β Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease (2007) (16)
- A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease (2020) (15)
- Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C (2017) (15)
- NIH workshop report on the trans-agency blood–brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interface (2017) (15)
- Microglia have a grip on brain microvasculature (2021) (15)
- Short-term fish oil supplementation applied in presymptomatic stage of Alzheimer's disease enhances microglial/macrophage barrier and prevents neuritic dystrophy in parietal cortex of 5xFAD mouse model (2019) (14)
- Pericyte constriction underlies capillary de-recruitment during hyperemia in the setting of arterial stenosis. (2019) (13)
- Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto. (2019) (13)
- Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats. (1994) (13)
- RMP-7, a bradykinin agonist, increases permeability of blood-ocular barriers in the guinea pig. (1995) (13)
- Corneal transport of circulating glutathione in normal and galactosemic guinea pigs. (1999) (13)
- Transport of Dopamine at the Blood-Brain Barrier of the Guinea Pig: Inhibition by Psychotropic Drugs and Nicotine (1996) (12)
- Neuroactive peptides and amino acids at the blood-brain barrier: possible implications for drug abuse. (1992) (12)
- APOE4 Accelerates Development of Dementia After Stroke: Is There a Role for Cerebrovascular Dysfunction? (2020) (12)
- Blood-Brain Barrier: A Dual Life of MFSD2A? (2014) (12)
- An in situ perfused guinea-pig eye model for blood-ocular transport studies: application to amino acids. (1992) (11)
- Low de novo glutathione synthesis from circulating sulfur amino acids in the lens epithelium. (1997) (11)
- Neurotoxicity of the anticoagulant-selective E149A-activated protein C variant after focal ischemic stroke in mice. (2013) (11)
- Differential Expression of Na , K-ATPase a ! and @ Subunit Isoforms at the Blood-Brain Barrier and the Choroid Plexus * (2001) (10)
- Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model (2021) (10)
- Haemostatic Functions of the Blood-Brain Barrier: Possible Implications in the Pathogenesis of Stroke (1995) (10)
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction (2019) (10)
- 7T multi-shell hybrid diffusion imaging (HYDI) for mapping brain connectivity in mice (2015) (10)
- Blood-brain barrier permeability changes during acute allergic encephalomyelitis induced in the guinea pig (1989) (10)
- Evidence that blood–CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with migraine frequency and CSF fibrinogen (2021) (9)
- Prenatal disruption of blood–brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation (2022) (9)
- The small HDL particle hypothesis of Alzheimer's disease (2022) (8)
- Influence of the 3K3A‐activated protein C variant on the plasma clot lysis activity of t‐PA and of t‐PA on the variant's anticoagulant activity (2013) (8)
- Retroviral vector-mediated transfer and expression of human tissue plasminogen activator cDNA in bovine brain endothelial cells. (1999) (7)
- Liver and lens glutathione and cysteine regulation in galactose-fed guinea pigs. (1997) (7)
- The effects of aluminum chloride on the rate of secretion of the cerebrospinal fluid (1987) (7)
- Imaging subtle leaks in the blood–brain barrier in the aging human brain: potential pitfalls, challenges, and possible solutions (2022) (7)
- Therapeutic TVs for Crossing Barriers in the Brain (2020) (7)
- Early neuroinflammation is associated with lower amyloid and tau levels in cognitively normal older adults (2021) (7)
- Rat brain capillary thrombomodulin: structure and function. (1998) (6)
- Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C (2021) (6)
- Brain barriers and their potential role in migraine pathophysiology (2022) (6)
- Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation (2021) (6)
- FOUR-YEAR LONGITUDINAL STUDY OF COGNITIVELY HEALTHY INDIVIDUALS: CSF AMYLOID/TAU LEVELS AND NANOPARTICLE MEMBRANES IDENTIFY HIGH RISK FOR ALZHEIMER’S DISEASE (2019) (6)
- Blood–Brain Barrier Transport of Alzheimer’s Amyloid β-Peptide (2016) (6)
- The effects of (R) alpha-methyl histamine on the isolated guinea pig aorta. (1991) (6)
- Amino acid transport by a glial blood-brain barrier: studies in an elasmobranch fish (1988) (5)
- Activated Protein C Analog With Reduced Anti-Coagulant Activity Improves Functional Recovery and Reduces Bleeding Risk Following Controlled Cortical Impact (2010) (5)
- Measurement of thrombomodulin mRNA expression in brain capillaries by polymerase chain reaction. (1998) (5)
- The blood-brain barrier in vitro: recent progress (1993) (5)
- Prion Protein Antagonists Rescue Alzheimer's Amyloid-β-Related Cognitive Deficits. (2019) (5)
- Investigating the blood–spinal cord barrier in preclinical models: a systematic review of in vivo imaging techniques (2021) (5)
- Immunoneurology: a serum protein afferent limb to the CNS. (1990) (5)
- History and Basic Concepts (1993) (5)
- Vasopressin uptake by hypothalamopituitary axis and pineal gland in guinea pigs. (1991) (5)
- Amino acids and the blood-brain barrier (1990) (4)
- Expression of Na,K-ATPase at the blood-brain interface. (1993) (4)
- Experimental psychosis and transport of amino acids and peptides across the blood-brain barrier (1988) (4)
- Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion (2021) (4)
- Survival and Toxicity of an Allogeneic Cytokine-secreting Fibroblast Vaccine in the Central Nervous System (1998) (4)
- Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium (2016) (3)
- Differential brain penetration of cerebroprotective drugs. (1993) (3)
- Intravenous Infusion of RMP-7 Increases Ocular Uptake of Ganciclovir (2004) (3)
- Current treatments and therapeutic targets in Alzheimer's disease. (2002) (3)
- Techniques for the study of the blood-brain barrier in non-mammalian species (1988) (3)
- A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice (2022) (3)
- Slow penetration of [3H] tiazofurin into guinea pig brain by a saturable mechanism. (1995) (3)
- Decreased glucose transporter 1 expression at the blood-brain barrier exacerbates Alzheimer disease-like phenotypes in mouse models (2017) (3)
- How the brain regulates its own immune system (2022) (3)
- 3K3A-Activated Protein C Protects the Blood-Brain Barrier and Neurons From Accelerated Ischemic Injury Caused by Pericyte Deficiency in Mice (2022) (3)
- Transport of apolipoproteins E and J at the blood-brain barrier. Relevance to Alzheimer's disease (1997) (3)
- Effects of sensory-motor cortical lesions on blood-brain permeability in guinea pigs (1989) (3)
- Role of the Blood—Brain Barrier in Immunopathogenesis of Experimentally Induced Autoimmune Demyelination (1992) (3)
- Characterization of perivascular space pathology in a rat model of cerebral small vessel disease by in vivo magnetic resonance imaging (2022) (3)
- Microhemorrhages: Undetectable but clinically meaningful the question persists (2011) (3)
- Transport of large peptides and proteins across the blood-brain barrier (1990) (3)
- Comparison between blood and saline perfusion on the uptake of amino acids by choroid plexus of the sheep. (1990) (2)
- Blood–Brain Barrier and Neurovascular Mechanisms of Neurodegeneration and Injury (2009) (2)
- Endothelial Tip Cell Finds Its Way with Piezo1 (2020) (2)
- Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier (2023) (2)
- In this important study, the authors have provided additional evidence in support of the concept that iNOS (1998) (2)
- Targeted cytotoxic gene delivery to malignant gliomas via the fibroblast growth factor receptor (2000) (2)
- Carrier-Mediated GSH Transport at the Blood–Brain Barrier and Molecular Characterization of Novel Brain GSH Transporters (2018) (2)
- A gliovascular idea for the white matter repair? (2013) (2)
- BLOOD-BRAIN BARRIER DAMAGE, NEURONAL DYSFUNCTION, AND DEGENERATION (2014) (2)
- NICARDIPINE ATTENUATES FOCAL ISCHEMIC BRAIN INJURY IN RATS (1996) (2)
- Neural Stem and Progenitor Cells: A Strategy for Gene Therapy and Brain Repair (1998) (2)
- PIKFYVE inhibition mitigates disease in models of diverse forms of ALS (2023) (1)
- Transport of Glucose and Amino Acids in the Central Nervous System (1993) (1)
- Reply to: Rethink the classical view of cerebrospinal fluid production (2021) (1)
- Neuroprotective effects of nicardipine in a rat model of ischemia and reperfusion (1997) (1)
- Peptides and Proteins (1993) (1)
- Correction: Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline (2020) (1)
- Review Article Vascular contributions to cognitive impairment and dementia including Alzheimer's disease (2014) (1)
- Blood—Brain Barrier Permeability to Peptides and Proteins (1992) (1)
- Penetration of [3H] Tiazofurin Into Guinea Pig Eye by a Saturable Mechanism (1995) (1)
- Uptake of Thiamine by the Isolated Perfused Sheep Choroid Plexus (1992) (1)
- Blood-brain transport of vasopressin. (1993) (1)
- Building vascular roadmaps: A novel toolset for visualizing and annotating whole mouse brain vasculature (2020) (1)
- Blood-brain barrier mechanisms of neurodegeneration in Alzheimer’s disease (2015) (1)
- Treatment of Brain Edema with a Nonpeptide Arginine Vasopressin V1 Receptor Antagonist OPC-21268 in Rats (1999) (1)
- Vascular Transport of Alzheimer’s Amyloid β Peptides and Apolipoproteins (2000) (1)
- Can prehospital “plasma supplement” neutralize the systemic storm in severe trauma? (2021) (1)
- Factors that influence the concentrations of amino acids in cerebrospinal fluid (1988) (1)
- Author Correction: APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β (2021) (1)
- Thrombotic Stroke : Neuroprotective Therapy by Recombinant-Activated Protein C (2016) (1)
- Neuron-like function of the nephron central command (2021) (1)
- Balancing dynamic tradeoffs drives cellular reprogramming (2018) (1)
- Reconstruction of major fibers using 7T multi-shell Hybrid Diffusion Imaging in mice (2015) (1)
- 582 In vivo blood-brain barrier uptake of Alzheimer's Aβ peptides in guinea pigs: Evidence for vascular sequestration of Aβ1-40 (but not Aβ1-42) (1996) (0)
- INCREASED CSF MATRIX METALLOPROTEINASE-9 (MMP-9) AND REDUCED WHITE MATTER INTEGRITY IN HEALTHY ELDERLY (2014) (0)
- The blood-brain barrier: Cellular and molecular biology Edited by William M. Pardridge. ISBN 0-7817-0015-9. Published by Raven Press, New York. 1993. pp. 476. $98.10 (1995) (0)
- Brain peptides and peptidergic pathways (1990) (0)
- NIH workshop report on the trans-agency blood–brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interface (2017) (0)
- Immunological and other aspects of the blood—brain barrier (1990) (0)
- O2-03-03 Inefficient LRP-mediated Aβ clearance at the blood-brain barrier contributes to neurotoxic and vasculotropic Aβ brain accumulations (2004) (0)
- From the editors (2011) (0)
- CLINICAL IMPLICATIONS OF BASIC NEUROSCIENCE RESEARCH (2016) (0)
- INTERACTIONS OF VASCULAR AND ALZHEIMER DISEASE (2016) (0)
- Epileptogenic Activity of Metaphitinduced Audiogenic Seizure in Small Rodents (1992) (0)
- S1-02-06 Clearance of Aβ (2006) (0)
- Acetylated tau: A missing link between head injury and dementia. (2021) (0)
- CSF SPDGFRB, A MEASURE OF VASCULAR DYSFUNCTION, IS RELATED TO DISRUPTED FUNCTIONAL CONNECTIVITY AMONG BRAIN REGIONS ASSOCIATED WITH ALZHEIMER’S DISEASE (2018) (0)
- P4-412 FC and non-FC dependent blood-brain barrier (BBB) clearance from brain to blood of anti-Aβ antibody in mice (2004) (0)
- Editorial for “MRI‐Based Investigation of Association Between Cerebrovascular Structural Alteration and White Matter Hyperintensity Induced by High Blood Pressure” (2021) (0)
- BIOLOGICAL UNDERPINNINGS OF VASCULAR CONTRIBUTIONS TO DEMENTIA (2016) (0)
- ASSOCIATIONS BETWEEN CEREBRAL BLOOD FLOW AND AMYLOID AND TAU PET BINDING IN AD-SPECIFIC REGIONS: FINDINGS FROM 2 INDEPENDENT COHORTS (2019) (0)
- P3-207 Activated protein protects neurons against Aβ (N-42, N-40) oligomers neurotoxicity (2004) (0)
- Altered Permeability Of The Blood‐CSF Barrier In Chronic Migraine (2018) (0)
- Glutathione synthesis from circulating sulfur amino acids is a minor source for the lens epithelial glutathione (1996) (0)
- CEREBROSPINAL FLUID MEASURES OF BLOOD BRAIN BARRIER INTEGRITY IN PSEN1-RELATED ALZHEIMER’S DISEASE (2017) (0)
- Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRβ, a marker of blood brain barrier breakdown, in older adults (2023) (0)
- CSF INTERLEUKIN-8, A KEY SIGNALING FACTOR FOR INFLAMMATION, IS ASSOCIATED WITH FUNCTIONAL CONNECTIVITY AND EXECUTIVE FUNCTION (2019) (0)
- CSF SPDGFRB, A MEASURE OF VASCULAR DYSFUNCTION, IS RELATED TO DISRUPTED FUNCTIONAL CONNECTIVITY AMONG BRAIN REGIONS ASSOCIATED WITH ALZHEIMER’S DISEASE (2018) (0)
- MOLECULAR AND CELL BIOLOGY: ABETA/AMYLOID O3-01-01 INTERACTION BETWEEN OBESITY, BRAIN HDL, AND APOE4 GENOTYPE IN CEREBRAL AMYLOIDOSIS CHRONIC BEHAVIORAL AND NEUROPATHOLOGICAL PHENOTYPES IN WILD-TYPE AND APP/PS1 MICE (2019) (0)
- Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias (2022) (0)
- New Insights Into the Blood-Brain Barrier (2015) (0)
- Glucagon effect on myocardial transport and utilization of energy-metabolites from the coronary microcirculation in the perfused rabbit heart. (1988) (0)
- Correction: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier (2023) (0)
- APOE4 blood‐brain barrier dysfunction: relation to cognitive impairment and molecular mechanisms (2022) (0)
- UPREGULATION OF ENDOTHELIAL PICALM EXPRESSION USING AN FDA-APPROVED DRUG REDUCES AMYLOID-β LOAD IN THE MURINE BRAIN (2019) (0)
- Characterization of spastic paraplegia in a family with a novel PSEN1 mutation (2023) (0)
- The relationship between blood‐brain barrier permeability and cerebral blood flow in cognitive impairment (2021) (0)
- S4-02-05: Blood-brain barrier mechanisms in Alzheimer's disease: Roles of rage and LRP (2008) (0)
- Relationships between cerebrovascular health and tau PET uptake are associated with global cognition (2020) (0)
- Urine dicarboxylic acids are metabolic biomarkers of early Alzheimer’s disease (2021) (0)
- Novel R41Q- and R46Q-PAR1-Modified Mice Enable Proof-of-Concept Studies for In Vivo Protective Mechanisms of Action for Activated Protein C (APC) in Sepsis and Stroke (2016) (0)
- Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism (2022) (0)
- Neurodegeneration and the Brain Barriers Contributors (2007) (0)
- O1-03-05 APOE isoform-specific inhibition of angiogenic transduction signaling pathways in human brain endothelium is regulated via LRP and megalin (2004) (0)
- The role of peptides in the brain (1990) (0)
- The regional relationship between CSF VEGF and white matter microstructural integrity in older adults: A voxelwise DTI study (2022) (0)
- Functional hyperconnectivity is associated with higher levels of sPDGFRβ, a marker of blood brain barrier breakdown, in older adults (2022) (0)
- Author Correction: Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. (2023) (0)
- P3-327 Drug target gene candidates for AD microvascular cells validated using laser capture microdissection (2004) (0)
- Strategies for peptide delivery to the brain (1990) (0)
- Abstract P750: 3K3A-APC Restores Oligodendrocyte Pools in Models of White Matter Stroke via PAR1 Signaling (2021) (0)
- MRI Studies Reporting Summary (2017) (0)
- THE BLOOD·BRAIN INTERFACE (1993) (0)
- Abstract WP139: MRI Evaluation and Functional Assessment of Brain Injury Improvement After 3K3A-Activated Protein C Treatment for Murine White Matter Stroke (2019) (0)
- Abstract WP134: 3K3A-APC Protects Pericyte-deficient Mice From Ischemic Brain Injury (2020) (0)
- ALZHEIMER’S DISEASE: A MATTER OF BLOOD-BRAIN BARRIER DYSFUNCTION? (2018) (0)
- The role of brain vasculature in neurodegenerative disorders (2018) (0)
- The interaction of small peptides with the various cellular interfaces of the blood-brain barrier (1990) (0)
- METABOLIC SYNDROME AND DEFAULT MODE NETWORK RSFMRI CONNECTIVITY IN THE HIPPOCAMPUS (2019) (0)
- ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology (2013) (0)
- Microglial activation: A process potentially related to Alzheimer's disease and late‐life major depression (2020) (0)
- Cerebrovascular Biology and the Various Neural Barriers: Challenges and Future Directions (1999) (0)
- Addition of Elemental Iodine to Surgical Irrigation for Shunt Infection Prophylaxis (1999) (0)
- BRAIN IMAGING OF VASCULAR DYSFUNCTION AS AN EARLY BIOMARKER OF COGNITIVE DECLINE (2019) (0)
- Edinburgh Research Explorer A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease (2020) (0)
- The liver and muscle secreted Hfe2-protein maintains blood brain barrier integrity (2021) (0)
- CEREBRAL PROTECTION FROM THE LAZAROID DES-METHYLTIRILAZAD (U-74389) (1997) (0)
- Methods for the study of the functions of the blood-brain barrier (1990) (0)
- Cellular and molecular neurosurgery: pathways from concept to reality--part II: vector systems and delivery methodologies for gene therapy of the central nervous system. (1997) (0)
- Building vascular roadmaps: A novel toolset for visualizing and annotating whole mouse brain vasculature (2020) (0)
- Editorial Board (2011) (0)
- Disease states and the blood-brain barrier related to peptides (1990) (0)
- INTERACTION BETWEEN OBESITY, BRAIN HDL, AND APOE4 GENOTYPE IN CEREBRAL AMYLOIDOSIS (2019) (0)
- 385 A Cell Resolution Atlas of the Human Cerebrovasculature Reveals Angiogenic and Inflammatory Cell Programs in Arteriovenous Malformations (2023) (0)
- A lymphatic waste-disposal system implicated in Alzheimer’s disease (2018) (0)
- INDEPENDENT OF CSF AMYLOID/TAU LEVELS, HIGHER (NORMAL) DIASTOLIC BLOOD PRESSURE IN COGNITIVELY HEALTHY SENIORS ASSOCIATES WITH BETTER (NORMAL) EXECUTIVE FUNCTION AND WITH LESSER (NORMAL) MEMORY (2019) (0)
- PERICYTE CONTRACTILITY BY OPTOGENETICS REGULATES CAPILLARY DIAMETER AND BLOOD FLOW (2019) (0)
- Abstract WP90: Activate Protein C Analog Protects Ischemic Injury of Subcortical White Matter in Mice (2018) (0)
- Vascular Endothelial Growth Factor Expression, Vascular Volume, and Capillary Permeability in Human Brain Tumors (1999) (0)
- Reactive Oxygen Species in Reoxygenation Injury of Rat Brain Capillary Endothelial Cells (1998) (0)
- NEUROINFLAMMATION IN ALZHEIMER’S DISEASE: TNF-α IS ASSOCIATED WITH ALTERED FUNCTIONAL CONNECTIVITY AMONG REWARD NETWORKS (2018) (0)
- RELATIONSHIP BETWEEN CSF Aβ42 LEVELS AND HIPPOCAMPAL SUBREGION VOLUMES (2019) (0)
- Advances in restorative neurosurgery: Endovascular delivery and fate determination of transplanted stem cells (2004) (0)
- On the intersection between systemic infection, brain vascular dysfunction and dementia. (2021) (0)
- Key Points * R 41 Q and R 46 Q point mutations in PAR 1 in mice enabled studies of APC ’ s in vivo mechanism of action in lethal sepsis and ischemic stroke (2018) (0)
- Anticonvulsant Effects of Phencyclidine and PCP-like Drugs on Audiogenic Seizures Induced by Metaphit in Mice (1992) (0)
- PYRAMIDAL SIGNS IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE (2018) (0)
- A NOVEL ASSAY FOR A BIOMARKER OF PERICYTE INJURY IN HUMAN CEREBROSPINAL FLUID (2019) (0)
- Opening of the Blood—Brain Barrier to D-Mannitol Induced by Sensorimotor Cortical Lesions in the Anaesthetized Guinea-pig (1992) (0)
- Transport of Some Precursors of Nucleotides and Some Vitamins (1993) (0)
- Subiculum fiber degeneration within the fornix white matter tract in 5xFAD mice (2022) (0)
- Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats (0)
- 583 Anti-amyloidogenic functions of the blood-brain barrier: Role of Gp330/megalin, and exclusion of apolipoproteins E3 and E4 (1996) (0)
- The uptake of dopamine by the caudate nucleus of perfused guinea pig brain (1994) (0)
- A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease (2020) (0)
- 3K3A-Activated Protein C Variant Does Not Interfere With the Plasma Clot Lysis Activity of Tenecteplase (2020) (0)
- Anti-TNF-alpha Antibody Reverses Experimental and Endotoxin Augmented Focal Ischemic Brain Injury: 793 (1997) (0)
- Corrigendum: Acute ablation of cortical pericytes leads to rapid neurovascular uncoupling (2022) (0)
- Abstract TMP27: Par1 Mediates Protective Effect of 3K3K-APC After White Matter Stroke in Mice (2020) (0)
- ID: 330 Neuroprotective mechanisms of activated protein C (2006) (0)
- Lens transport of ascorbic acid in guinea pigs, normal, galactose-fed and with congenital cataract (1996) (0)
- Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism (2018) (0)
- P3-326 Dysregulation in serum response factor and myocardin in Alzheimer's cerebral arterial system (2004) (0)
- 2313 Characterization of the host pericyte role in glioblastoma angiogenesis (2018) (0)
- Experimental Models in the Study of the Pathology of the Blood-Brain Barrier (1993) (0)
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