Bernhard Ryffel

Q: What Schools Are Affiliated With Bernhard Ryffel

Bernhard Ryffel is affiliated with the following schools: University of Cape Town, ETH Zurich, University of Edinburgh, University of Basel, University of Bern, University of Geneva, University of Orléans, University of Zurich

Bernhard Ryffel's AcademicInfluence.com Rankings

Bernhard Ryffel

Computer Science

#4396

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#4631

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Machine Learning

#848

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#860

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Artificial Intelligence

#1057

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#1076

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Database

#1605

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#1683

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computer-science Degrees

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Computer Science

Bernhard Ryffel's Degrees

PhD Computer Science ETH Zurich
Masters Computer Science University of Zurich
Bachelors Computer Science University of Zurich

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Bernhard Ryffel's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors (2018) (3049)
Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy (2007) (2668)
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors (2009) (1606)
The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide (2013) (1421)
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. (2010) (837)
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands (2016) (817)
Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors (2007) (676)
Interleukin-17 is a negative regulator of established allergic asthma (2006) (628)
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth (2012) (616)
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. (2013) (466)
A novel dendritic cell subset involved in tumor immunosurveillance (2006) (448)
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. (2007) (439)
Antifibrotic and Anti-inflammatory Activity of the Tyrosine Kinase Inhibitor Nintedanib in Experimental Models of Lung Fibrosis (2014) (435)
Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. (2010) (362)
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. (2016) (361)
Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. (2004) (356)
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. (2004) (348)
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. (2009) (346)
Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects. (2005) (336)
Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. (2004) (336)
IL-1 Receptor-Mediated Signal Is an Essential Component of MyD88-Dependent Innate Response to Mycobacterium tuberculosis Infection (2007) (318)
Interferon gamma receptor deficient mice are resistant to endotoxic shock (1994) (317)
Cutting Edge: Priming of NK Cells by IL-181 (2008) (297)
IL-18 induces PD-1-dependent immunosuppression in cancer. (2011) (296)
Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. (2012) (292)
Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. (2007) (290)
Toll-like receptor pathways in the immune responses to mycobacteria. (2004) (289)
IL‐33‐activated dendritic cells are critical for allergic airway inflammation (2011) (287)
The side-effects of ciclosporine-A and tacrolimus. (1998) (287)
The receptor NLRP3 is a transcriptional regulator of TH2 differentiation (2015) (275)
Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice1 (2002) (265)
IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice. (1997) (253)
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity (2011) (247)
IL-17A Plays a Critical Role in the Pathogenesis of Liver Fibrosis through Hepatic Stellate Cell Activation (2013) (244)
Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein. (1989) (238)
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling (1996) (237)
Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent1 (2008) (218)
ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation (2012) (216)
Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation (2010) (216)
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. (2012) (210)
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice (1996) (209)
Immunopathologic Effects of Tumor Necrosis Factor Alpha in Murine Mycobacterial Infection Are Dose Dependent (2000) (208)
Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon‐γ receptor inhibits the onset of glomerulonephritis (1995) (206)
Interferon-λ and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection (2015) (205)
Toll-Like Receptor 2 (TLR2)-Dependent-Positive and TLR2-Independent-Negative Regulation of Proinflammatory Cytokines by Mycobacterial Lipomannans1 (2004) (203)
IFN-γ Receptor Deletion Prevents Autoantibody Production and Glomerulonephritis in Lupus-Prone (NZB × NZW)F1 Mice (1998) (198)
Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. (2011) (198)
Histopathology of cyclosporine nephrotoxicity. (1988) (192)
The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells (2014) (191)
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions (2014) (189)
IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice. (1998) (188)
Toll-Like Receptor 2 Is Required for Optimal Control of Listeria monocytogenes Infection (2004) (187)
Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy (2011) (185)
iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice (2009) (184)
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice (2012) (181)
IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis (2011) (178)
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. (2005) (176)
Double-stranded RNAs from the Helminth Parasite Schistosoma Activate TLR3 in Dendritic Cells* (2005) (176)
Microbial metabolites control the thymic development of mucosal-associated invariant T cells (2019) (172)
Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection (2012) (168)
Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. (2013) (167)
Trypanosomiasis-Induced B Cell Apoptosis Results in Loss of Protective Anti-Parasite Antibody Responses and Abolishment of Vaccine-Induced Memory Responses (2008) (162)
Constitutive Expression of Interleukin (IL)-4 In Vivo Causes Autoimmune-type Disorders in Mice (1997) (162)
Sensing prokaryotic mRNA signifies microbial viability and promotes immunity (2011) (161)
Reactivation of Latent Tuberculosis Infection in TNF-Deficient Mice 1 (2003) (160)
NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant (2011) (158)
TNF-α Controls Intracellular Mycobacterial Growth by Both Inducible Nitric Oxide Synthase-Dependent and Inducible Nitric Oxide Synthase-Independent Pathways1 (2001) (158)
Cutting Edge: Crucial Role of IL-1 and IL-23 in the Innate IL-17 Response of Peripheral Lymph Node NK1.1− Invariant NKT Cells to Bacteria (2011) (156)
Oxeiptosis – a ROS induced caspase-independent apoptosis-like cell death pathway (2017) (153)
Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? (2012) (152)
Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice (2002) (150)
Distribution of the cyclosporine binding protein cyclophilin in human tissues. (1991) (150)
Dominant-Negative Inhibitors of Soluble TNF Attenuate Experimental Arthritis without Suppressing Innate Immunity to Infection (2007) (150)
Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice. (1994) (149)
Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain. (1996) (149)
Role of ICAM-1 (CD54) in the development of murine cerebral malaria. (1999) (142)
The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent1 (2005) (141)
Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs (2009) (140)
TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa (2010) (139)
Morphological patterns in cyclosporine-treated renal transplant recipients. (1985) (138)
Inflammasome-IL-1-Th17 response in allergic lung inflammation. (2012) (138)
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes (2007) (134)
STING-dependent sensing of self-DNA drives silica-induced lung inflammation (2018) (131)
Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. (2012) (128)
Role of interferon-gamma in interleukin 12-induced pathology in mice. (1995) (126)
Migration of Langerhans cells and dermal dendritic cells in skin organ cultures: augmentation by TNF‐α and IL‐1 β (1999) (124)
Both Hemopoietic and Resident Cells Are Required for MyD88-Dependent Pulmonary Inflammatory Response to Inhaled Endotoxin1 (2005) (122)
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer (2018) (121)
The differential diagnosis between rejection and cyclosporine toxicity. (1995) (121)
Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome (2016) (121)
All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus (2011) (120)
Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response. (1997) (119)
Toll‐like receptor and tumour necrosis factor dependent endotoxin‐induced acute lung injury (2007) (119)
Tumor Necrosis Factor Alpha-Mediated Toxic Shock inTrypanosoma cruzi-Infected Interleukin 10-Deficient Mice (2000) (114)
IL-17A–Producing γδ T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis (2010) (114)
MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury. (2013) (113)
Spinal cord oligodendrocyte‐derived alarmin IL‐33 mediates neuropathic pain (2016) (112)
Acylation Determines the Toll-like receptor (TLR)-dependent Positive Versus TLR2-, Mannose Receptor-, and SIGNR1-independent Negative Regulation of Pro-inflammatory Cytokines by Mycobacterial Lipomannan* (2007) (111)
The course of Plasmodium chabaudi chabaudi infections in interferon‐gamma receptor deficient mice (1997) (109)
Increased resistance to mycobacterial infection in the absence of interleukin‐10 (2000) (109)
Membrane-associated Hsp 72 from tumor-derived exosomes mediates STAT 3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells (2010) (109)
Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands. (2010) (107)
Murine cerebral malaria development is independent of toll-like receptor signaling. (2007) (107)
The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles (2014) (103)
Dual Effects of p38 MAPK on TNF-Dependent Bronchoconstriction and TNF-Independent Neutrophil Recruitment in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome1 (2005) (103)
IL-33-Mediated Protection against Experimental Cerebral Malaria Is Linked to Induction of Type 2 Innate Lymphoid Cells, M2 Macrophages and Regulatory T Cells (2015) (103)
IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema1 (2009) (101)
Neutrophil Influx in Response to a Peritoneal Infection with Salmonella Is Delayed in Lipopolysaccharide-Binding Protein or CD14-Deficient Mice1 (2002) (101)
Tumor necrosis factor is critical to control tuberculosis infection. (2007) (101)
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. (2012) (101)
Overexpression of Toll-Like Receptor 4 Amplifies the Host Response to Lipopolysaccharide and Provides a Survival Advantage in Transgenic Mice 1 (2003) (101)
Prominent role for T cell-derived Tumour Necrosis Factor for sustained control of Mycobacterium tuberculosis infection (2013) (100)
AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging (2018) (99)
Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. (1998) (97)
Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection. (2015) (97)
Toll-like receptor 2 is critical for induction of Reg3β expression and intestinal clearance of Yersinia pseudotuberculosis (2009) (94)
Toll-Like Receptor 2 (TLR2)-Dependent-Positive and TLR2-Independent-Negative Regulation of Proinflammatory Cytokines by Mycobacterial Lipomannans (2004) (94)
Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice. (2010) (92)
Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation (2012) (91)
The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo (1995) (89)
Morphology of cyclosporine nephrotoxicity in the rat. (1986) (88)
Crucial Role of Gamma Interferon-Producing CD4+ Th1 Cells but Dispensable Function of CD8+ T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice (2012) (87)
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice (2019) (87)
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer (2020) (87)
Lethal Mycobacterium Bovis Bacillus Calmette Guérin Infection in Nitric Oxide Synthase 2-Deficient Mice: Cell-Mediated Immunity Requires Nitric Oxide Synthase 2 (2000) (84)
Collective nitric oxide production provides tissue-wide immunity during Leishmania infection. (2014) (83)
The Microtubule Regulator Stathmin Is an Endogenous Protein Agonist for TLR3 (2010) (83)
Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. (2015) (83)
Correction or Transfer of Immunodeficiency Due to TNF-LTα Deletion by Bone Marrow Transplantation (1996) (82)
Cyclosporin receptors on human lymphocytes. (1982) (82)
Complement C5 Activation during Influenza A Infection in Mice Contributes to Neutrophil Recruitment and Lung Injury (2013) (82)
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade (2020) (82)
Partial Redundancy of the Pattern Recognition Receptors, Scavenger Receptors, and C-Type Lectins for the Long-Term Control of Mycobacterium tuberculosis Infection (2010) (81)
Double-Stranded RNA Exacerbates Pulmonary Allergic Reaction through TLR3: Implication of Airway Epithelium and Dendritic Cells (2010) (81)
Mast cells induce autoantibody-mediated vasculitis syndrome through tumor necrosis factor production upon triggering Fcgamma receptors. (1999) (80)
Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. (1998) (80)
Nrf2, a PPARγ Alternative Pathway to Promote CD36 Expression on Inflammatory Macrophages: Implication for Malaria (2011) (79)
Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome. (2014) (79)
The Emerging Roles of STING in Bacterial Infections. (2017) (79)
Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy (2011) (78)
IFN-γ Production Depends on IL-12 and IL-18 Combined Action and Mediates Host Resistance to Dengue Virus Infection in a Nitric Oxide-Dependent Manner (2011) (77)
Crucial Role of Tumor Necrosis Factor Receptor 1 Expression on Nonhematopoietic Cells for B Cell Localization within the Splenic White Pulp (1998) (76)
Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes. (2018) (76)
B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis. (2015) (76)
Uric Acid-Driven Th17 Differentiation Requires Inflammasome-Derived IL-1 and IL-18 (2011) (76)
Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells. (2008) (76)
AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome. (2016) (76)
VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases (2007) (75)
TLR4 gene dosage contributes to endotoxin‐induced acute respiratory inflammation (2006) (74)
Dengue virus infection: current concepts in immune mechanisms and lessons from murine models (2014) (74)
In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice (2012) (73)
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis (2008) (72)
Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway (2010) (71)
Oxidative Stress in Ozone-Induced Chronic Lung Inflammation and Emphysema: A Facet of Chronic Obstructive Pulmonary Disease (2020) (71)
Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL‐33 (2018) (70)
Interleukin-33 Increases Antibacterial Defense by Activation of Inducible Nitric Oxide Synthase in Skin (2014) (70)
Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model (2017) (69)
Innate immunity to mycobacterial infection in mice: critical role for toll-like receptors. (2005) (69)
Membrane tumor necrosis factor confers partial protection to Listeria infection. (2005) (69)
NOD 2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer (2013) (69)
Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome. (2012) (69)
Membrane TNF confers protection to acute mycobacterial infection (2005) (68)
TLR9-Dependent Induction of Intestinal α-Defensins by Toxoplasma gondii (2010) (68)
Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension (2016) (68)
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. (1996) (67)
Toll‐like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin‐specific allergic airway disease: role of MyD88 adaptor molecule and interleukin‐12/interferon‐γ axis (2008) (67)
Pharmacology of cyclosporine (sandimmune). I. Introduction. (1990) (67)
Identification of interleukin 4 receptor‐associated proteins and expression of both high‐ and low‐affinity binding on human lymphoid cells (1989) (67)
Toxicological evaluation of cyclosporin A (1983) (66)
Interleukin-12: Role of Interferon-γ in IL-12 Adverse Effects (1997) (65)
Role of interferon-gamma in contact hypersensitivity assessed in interferon-gamma receptor-deficient mice. (1995) (65)
Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells (2018) (65)
Toll-like receptor 2 is essential for the sensing of oxidants during inflammation. (2009) (65)
Humoral Immunity and CD4+ Th1 Cells Are Both Necessary for a Fully Protective Immune Response upon Secondary Infection with Brucella melitensis (2014) (65)
Correction of Defective Host Response to Mycobacterium Bovis BCG Infection in TNF-Deficient Mice by Bone Marrow Transplantation (2000) (64)
Role of the Chemokine Receptors CCR1, CCR2 and CCR4 in the Pathogenesis of Experimental Dengue Infection in Mice (2010) (64)
CD14 works with toll-like receptor 2 to contribute to recognition and control of Listeria monocytogenes infection. (2008) (63)
Fatal Mycobacterium bovis BCG infection in TNF-LT-α-deficient mice (2000) (63)
TNF in host resistance to tuberculosis infection. (2010) (63)
Mycobacterial Phosphatidylinositol Mannosides Negatively Regulate Host Toll-like Receptor 4, MyD88-dependent Proinflammatory Cytokines, and TRIF-dependent Co-stimulatory Molecule Expression* (2009) (63)
Tumor necrosis factor receptors in lymphoid tissues and lymphomas. Source and site of action of tumor necrosis factor alpha. (1991) (63)
Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture. (1994) (62)
Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. (2014) (62)
Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG (2013) (62)
Long-Term Control of Mycobacterium bovis BCG Infection in the Absence of Toll-Like Receptors (TLRs): Investigation of TLR2-, TLR6-, or TLR2-TLR4-Deficient Mice (2004) (62)
Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells (2018) (62)
Airway structural cells regulate TLR5-mediated mucosal adjuvant activity (2013) (62)
The function of BAFF on T helper cells in autoimmunity. (2014) (61)
Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation. (2008) (61)
Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. (2001) (61)
Morphology of ciclosporin nephropathy. (1986) (60)
Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Mycobacterium smegmatis-Induced Cytokine Production by Human Macrophages In Vitro (2001) (59)
Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. (2007) (58)
Pharmacology of cyclosporine. VI. Cellular activation: regulation of intracellular events by cyclosporine. (1990) (58)
IMQ‐induced skin inflammation in mice is dependent on IL‐1R1 and MyD88 signaling but independent of the NLRP3 inflammasome (2015) (57)
Tumor necrosis factor (TNF) receptor-1 (TNFp55) signal transduction and macrophage-derived soluble TNF are crucial for nitric oxide-mediated Trypanosoma congolense parasite killing. (2007) (57)
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin (2020) (56)
Transmembrane TNF‐α is sufficient for articular inflammation and hypernociception in a mouse model of gout (2016) (56)
Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1. (2012) (56)
Role of reactive oxygen formation in the cyclosporin-A-mediated impairment of renal functions. (1994) (55)
Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate. (1982) (55)
Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin (2009) (55)
TNF receptor distribution in human tissues. (1993) (55)
Nitric oxide enhances Th9 cell differentiation and airway inflammation (2014) (55)
Interferon‐γ is essential for the development of cerebral malaria (1997) (55)
Interferon-gamma is essential for the development of cerebral malaria. (1997) (55)
Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection. (2014) (54)
Trans-Presentation of IL-15 Dictates IFN-Producing Killer Dendritic Cells Effector Functions1 (2008) (54)
PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity. (2018) (54)
SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth. (2013) (54)
Nephrotoxicity of cyclosporine in spontaneously hypertensive rats: effects on blood pressure and vascular lesions. (1986) (53)
The Critical Role of IL-15 in the Antitumor Effects Mediated by the Combination Therapy Imatinib and IL-21 (2008) (53)
The development and function of follicular helper T cells in immune responses (2012) (52)
Enhancement of Methacholine-Evoked Tracheal Contraction Induced by Bacterial Lipopolysaccharides Depends on Epithelium and Tumor Necrosis Factor (2012) (52)
Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide. (2012) (52)
Morphological criteria of chronic rejection: differential diagnosis, including cyclosporine nephropathy. (1993) (51)
Targeting the NLRP3 inflammasome to Reduce Diet-induced Metabolic Abnormalities in Mice (2015) (51)
Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes. (2007) (51)
Rodent nutritional model of steatohepatitis: Effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency (2006) (51)
IL‐22 modulates IL‐17A production and controls inflammation and tissue damage in experimental dengue infection (2013) (50)
Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro. (2006) (50)
RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. (2013) (50)
Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1β and IL-18 in mice. (2014) (50)
Both Functional LTβ Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria (2008) (50)
Tumour necrosis factor receptor distribution in human lymphoid tissue. (1991) (49)
Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis. (2009) (49)
Endogenous leukemia inhibitory factor attenuates endotoxin response (2005) (49)
IL-17 reduces TNF-induced Rantes and VCAM-1 expression. (2005) (49)
MyD88 Signaling in B Cells Regulates the Production of Th1-dependent Antibodies to AAV (2012) (48)
The carcinogenicity of ciclosporin. (1992) (48)
Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood‐stage Plasmodium berghei ANKA (2013) (48)
Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis1 (2009) (47)
Tumor Necrosis Factor Receptor 2 Plays a Minor Role for Mycobacterial Immunity (2000) (47)
The development of murine cerebral malaria does not require nitric oxide production (1999) (47)
Cyclosporin receptor on mouse lymphocytes. (1980) (47)
Nephrotoxic and immunosuppressive potentials of cyclosporine metabolites in rats. (1986) (46)
Resistance of TNF/LTα double deficient mice to bleomycin‐induced fibrosis (1997) (46)
Arthropod-Derived Histamine-Binding Protein Prevents Murine Allergic Asthma (2004) (46)
NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction (2017) (46)
A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation (2017) (45)
IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria (2017) (45)
Identification of cyclophilin as the erythrocyte ciclosporin-binding protein. (1988) (45)
TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection. (2009) (45)
The Mechanism of Action of Ciclosporin: A Continuing Puzzle (1985) (45)
Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. (1995) (45)
Parasite killing in murine malaria does not require nitric oxide production (1999) (45)
Anti-Pseudomonas aeruginosa serotype O11 LPS immunoglobulin M monoclonal antibody panobacumab (KBPA101) confers protection in a murine model of acute lung infection. (2011) (45)
microRNA cluster 106a~363 is involved in T helper 17 cell differentiation (2017) (44)
Chronic pneumonia despite adaptive immune response to Mycobacterium bovis BCG in MyD88-deficient mice (2004) (44)
Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells (2017) (44)
Response to Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent” (2008) (44)
Characterization of a human T cell-specific chimeric antibody (CD7) with human constant and mouse variable regions. (1989) (44)
Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production (2015) (44)
CYCLOSPORINE—RELATIONSHIP OF SIDE EFFECTS TO MODE OF ACTION (1988) (44)
Studies on the biologic activities of Sandimmun metabolites in humans and in animal models: review and original experiments. (1990) (43)
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model (2013) (42)
Role of pattern-recognition receptors in cardiovascular health and disease. (2007) (42)
Differential roles of tumor necrosis factor-alpha and interferon-gamma in mouse hypermetabolic and anorectic responses induced by LPS. (2000) (42)
Reactivation of tuberculosis by tumor necrosis factor neutralization. (2007) (42)
Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice (2014) (42)
In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria (2015) (42)
Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology. (2007) (42)
Lack of type 2 T cell-independent B cell responses and defect in isotype switching in TNF-lymphotoxin alpha-deficient mice. (1997) (41)
Renal transplant morphology after long-term therapy with cyclosporine. (1995) (41)
Interleukin‐17/interleukin‐17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high‐fat diet‐induced metabolic syndrome model (2018) (41)
Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice. (2017) (40)
The dual role of LBP and CD14 in response to Gram-negative bacteria or Gram-negative compounds (2003) (40)
GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE2 in Response to TLR2 Ligands (2012) (39)
Fatal Mycobacterium bovis BCG infection in TNF-LT-alpha-deficient mice. (2000) (39)
Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis. (2014) (39)
Inflammasome, IL-1 and inflammation in ozone-induced lung injury. (2016) (38)
ELUCIDATION OF TOLL-LIKE RECEPTOR AND ADAPTER PROTEIN SIGNALING IN VASCULAR DYSFUNCTION INDUCED BY GRAM-POSITIVE STAPHYLOCOCCUS AUREUS OR GRAM-NEGATIVE ESCHERICHIA COLI (2007) (38)
IL-12Rβ2 Is Essential for the Development of Experimental Cerebral Malaria (2012) (38)
Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of Th17 cells in the lymph nodes (2018) (38)
Inhibition of the NLRP3 inflammasome prevents ovarian aging (2020) (37)
MyD88 is essential for alveolar bone loss induced by Aggregatibacter actinomycetemcomitans lipopolysaccharide in mice. (2013) (37)
Morphologic diagnosis of cyclosporine nephrotoxicity. (1988) (37)
Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy (2017) (37)
Comparison of the pharmacological profiles of cyclosporine, (Nva2)-cyclosporine and (Val2)dihydro-cyclosporine. (1985) (37)
Mycobacterium tuberculosis infection of the ‘non‐classical immune cell’ (2015) (37)
Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model (2002) (37)
Differential role of all‐trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells (2014) (36)
Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells (2018) (36)
Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections (2017) (36)
IL-36γ Induced by the TLR3-SLUG-VDR Axis Promotes Wound Healing via REG3A. (2017) (36)
Distribution and activity of calcineurin in rat tissues. Evidence for post-transcriptional regulation of testis-specific calcineurin B. (1995) (36)
EFFECT OF CYCLOSPORIN ON RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (1982) (36)
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses (2020) (36)
Self-DNA Sensing in Lung Inflammatory Diseases. (2019) (36)
Acute Respiratory Barrier Disruption by Ozone Exposure in Mice (2019) (36)
Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate-- the marmoset (1994) (35)
Renal side‐effects of cyclosporin A with special reference to autoimmune diseases (1990) (35)
AhR modulates the IL‐22‐producing cell proliferation/recruitment in imiquimod‐induced psoriasis mouse model (2016) (35)
Bifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung Injury (2013) (35)
Enhanced Immune Response in Mycobacterium bovis Bacille Calmette Guerin (BCG)-Infected IL-10-Deficient Mice (2002) (35)
Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection. (2011) (35)
Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice (2018) (35)
Growth inhibition of human colorectal‐carcinoma cells by interleukin‐4 and expression of functional interleukin‐4 receptors (1994) (34)
Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization (2016) (34)
The Anti-Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropenic Mice and Has Additive Effects with Meropenem (2013) (34)
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens (2018) (34)
Protective role of membrane tumour necrosis factor in the host’s resistance to mycobacterial infection (2008) (33)
Gain of function mutation and inflammasome driven diseases in human and mouse models. (2018) (33)
Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection (2015) (33)
TLR2 Is Necessary to Inflammatory Response in Coxiella burnetii Infection (2005) (33)
Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses. (2007) (33)
Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection. (2016) (33)
MyD88 as a therapeutic target for inflammatory lung diseases (2018) (33)
IL‐1α induces CD11blow alveolar macrophage proliferation and maturation during granuloma formation (2015) (33)
Type I interferon signaling contributes to chronic inflammation in a murine model of silicosis. (2010) (33)
Antigen Targeting to CD11b+ Dendritic Cells in Association with TLR4/TRIF Signaling Promotes Strong CD8+ T Cell Responses (2014) (33)
Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins. (1993) (31)
TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis (2015) (31)
A detrimental role for invariant natural killer T cells in the pathogenesis of experimental dengue virus infection. (2011) (31)
Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths (2021) (31)
Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 – April 1, 2016, Tours, France (2016) (31)
Immunosuppression and cancer: the ciclosporin case. (1992) (31)
IL-17A Modulates Oxidant Stress-Induced Airway Hyperresponsiveness but Not Emphysema (2013) (31)
A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy (2021) (31)
Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice (2019) (30)
Pathology induced by interleukin-6. (1992) (30)
Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice (2016) (30)
GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection (2018) (30)
Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway (2017) (30)
Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF (2015) (30)
Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo. (1992) (29)
Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways (2006) (29)
Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses. (1995) (29)
PGE2 reduces nephrotoxicity and immunosuppression of cyclosporine in rats. (1986) (28)
Critical role of IL‐33 receptor ST2 in experimental cerebral malaria development (2015) (28)
Contribution of IL-17-producing gammadelta T cells to the efficacy of anticancer chemotherapy. (2020) (28)
The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation (2016) (28)
Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice. (2013) (27)
CD3+ Macrophages Deliver Proinflammatory Cytokines by a CD3- and Transmembrane TNF-Dependent Pathway and Are Increased at the BCG-Infection Site (2019) (27)
In situ detection of cyclosporin A: evidence for nuclear localization of cyclosporine and cyclophilins. (1995) (27)
Crescentic glomerulonephritis in interferon-gamma receptor deficient mice. (1995) (27)
Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8+ T Cells (2012) (27)
Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring (2019) (26)
Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. (2021) (26)
The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin (2018) (26)
Cyclosporin A: action and side-effects. (1989) (26)
Resistance of TNF/LT alpha double deficient mice to bleomycin-induced fibrosis. (1997) (26)
Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses (2022) (26)
Protein kinase C-theta is required for development of experimental cerebral malaria. (2011) (26)
NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity. (2020) (26)
Diagnostic accuracy of a selected signature gene set that discriminates active pulmonary tuberculosis and other pulmonary diseases. (2017) (26)
Control of allergic reactions in mice by an active anti-murine IL-4 immunization. (2007) (25)
Immunogold-silver/Romanowsky staining: simultaneous immunocytochemical and morphologic analysis of fine-needle aspirate biopsies. (1988) (25)
Impact of knockout mice in toxicology. (1997) (25)
Novel Bacterial Delivery System with Attenuated Salmonella typhimurium Carrying Plasmid Encoding Mtb Antigen 85A for Mucosal Immunization: Establishment of Proof of Principle in TB Mouse Model (2005) (25)
TUMOR NECROSIS FACTOR IS NOT ASSOCIATED WITH INTESTINAL ISCHEMIA/REPERFUSION-INDUCED LUNG INFLAMMATION (2010) (25)
Nephrotoxicity of immunosuppressants in rats: comparison of macrolides with cyclosporin. (1994) (25)
Oxidized hemoglobin forms contribute to NLRP3 inflammasome-driven IL-1β production upon intravascular hemolysis. (2019) (25)
Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity. (2019) (25)
Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation (2018) (25)
Anti-CD3 antibody-induced expression of both p55 and p75 chains of the high affinity interleukin-2 receptor on human T lymphocytes is inhibited by cyclosporin A. (1990) (24)
Protein kinase C&THgr; controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen (2017) (24)
Cyclosporin. Toxicology--experimental studies. (1986) (23)
Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation (2018) (23)
Contribution of TNF/TNF receptor and of Fas ligand to toxicity in murine models of endotoxemia and bacterial peritonitis. (1995) (23)
Binding of active cyclosporins to cyclophilin A and B, complex formation with calcineurin A. (1993) (23)
Immunosuppressive effect of cyclosporin A in two lymphocyte transfer models in rats: comparison of in vivo and in vitro treatment. (1982) (23)
Cyclosporin A enhances the calcium-dependent induction of AP-1 complex and c-fos mRNA in a T cell lymphoma. (1996) (22)
The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection (2018) (22)
Induced Foxp 3 + regulatory T cells : a potential new weapon to treat autoimmune and inflammatory diseases ? (2012) (22)
Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain (2015) (22)
Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation (2020) (22)
Tenascin‐C triggers fibrin accumulation by downregulation of tissue plasminogen activator (2011) (22)
Oral artesunate prevents Plasmodium berghei Anka infection in mice. (2003) (22)
Failure to induce anti‐glomerular basement membrane glomerulonephritis in TNFα/β deficient mice (1998) (21)
Effect of rapamycin on the expression of the IL‐2 receptor (CD25) (1996) (21)
Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose (2018) (21)
IFN‐γ mediates early B‐cell loss in experimental African trypanosomosis (2015) (21)
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS) (2022) (21)
Interleukin‐23 promotes intestinal T helper type17 immunity and ameliorates obesity‐associated metabolic syndrome in a murine high‐fat diet model (2018) (21)
Efficacy of membrane TNF mediated host resistance is dependent on mycobacterial virulence. (2008) (21)
Pharmacokinetics of cyclosporine in toxicological studies. (1986) (20)
Limited Role for Lymphotoxin α in the Host Immune Response to Mycobacterium tuberculosis (2010) (20)
Sandimmun metabolites: their potential to cause adverse reactions in the rat. (1990) (20)
IL‐1R1–MyD88 axis elicits papain‐induced lung inflammation (2016) (20)
Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1. (1996) (20)
SYNGENEIC GRAFT‐VERSUS‐HOST DISEASE INDUCED BY CYCLOSPORINE—A REAPPRAISAL (1988) (20)
Allergic lung inflammation is mediated by soluble tumor necrosis factor (TNF) and attenuated by dominant-negative TNF biologics. (2011) (20)
Toxicologic evaluation of the new cyclosporin derivative, SDZ IMM 125, in a comparative, subchronic toxicity study in rats. (1992) (20)
Biotinylated recombinant interleukin-2. A tool for research on the interleukin-2 receptor. (1988) (20)
Anisakis pegreffii-Induced Airway Hyperresponsiveness Is Mediated by Gamma Interferon in the Absence of Interleukin-4 Receptor Alpha Responsiveness (2010) (20)
IFN-7 Is Essential for the Development of Autoimmune Glomerulonephritis in MRL / lpr Mice ' (2001) (19)
A New Bifidobacteria Expression SysTem (BEST) to Produce and Deliver Interleukin-10 in Bifidobacterium bifidum (2018) (19)
Ciclosporin-associated Nephropathy (1985) (19)
Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC (2014) (19)
Role of IL-1β in Experimental Cystic Fibrosis upon P. aeruginosa Infection (2014) (19)
Toxicology – Experimental Studies (1986) (18)
Petasites extract Ze 339 (PET) inhibits allergen‐induced Th2 responses, airway inflammation and airway hyperreactivity in mice (2010) (18)
Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for cyclosporine. (1991) (18)
Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy. (1986) (18)
Interferon-gamma enhances tumor necrosis factor-alpha production by inhibiting early phase interleukin-10 transcription. (1996) (17)
Interleukin-12: role of interferon-gamma in IL-12 adverse effects. (1997) (17)
Biologic significance of cyclosporine metabolites. (1988) (17)
The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice. (2010) (17)
Cancer induces a stress ileopathy depending on B-adrenergic receptors and promoting dysbiosis that contribute to carcinogenesis. (2021) (17)
Remote control of intestinal tumorigenesis by innate immunity. (2010) (17)
Light and electron microscopic changes in the kidney of Wistar rats following treatment with cyclosporine A. (1987) (17)
Alterations in molecular structure of renal mitochondria associated with cyclosporine A treatment. (1986) (17)
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice (2020) (17)
IL-33 signalling in liver immune cells enhances drug-induced liver injury and inflammation (2017) (17)
Histamine Plays an Essential Regulatory Role in Lung Inflammation and Protective Immunity in the Acute Phase of Mycobacterium tuberculosis Infection (2009) (16)
Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge (2016) (16)
Successful treatment of autoimmunity in (NZB X NZW)F1 mice with cyclosporin and (Nva2)-cyclosporin: II. Reduction of glomerulonephritis. (1986) (16)
Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension (2018) (16)
Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection. (2008) (16)
Neurons Are Host Cells for Mycobacterium tuberculosis (2014) (16)
Tumor Necrosis Factor and Its Receptors Are Crucial to Control Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection in a Murine Model. (2016) (16)
Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation (2013) (16)
Regulatory T cells: A potential weapon to combat COVID‐19? (2020) (16)
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments (2020) (16)
Gene knockout mice as investigative tools in pathophysiology (1996) (16)
Histamine H2 Receptor Signaling in the Pathogenesis of Sepsis: Studies in a Murine Diabetes Model (2013) (15)
Interleukin-2 receptor (CD25) upregulation on human T-lymphocytes: sensitivity to immunosuppressants is defined by the mode of T-lymphocyte activation. (1995) (15)
Toll-like receptors and control of mycobacterial infection in mice. (2006) (15)
A COMPARISON OF CYCLOSPORINE BINDING BY CYCLOPHILIN AND CALMODULIN AND THE IDENTIFICATION OF A NOVEL 45 KD CYCLOSPORINE‐BINDING PHOSPHOPROTEIN IN JURKAT CELLS (1988) (15)
Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection (2021) (15)
MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection (2013) (15)
SRI 62-834, a cyclic ether analogue of the phospholipid ET-18-OCH3, displays long-lasting beneficial effect in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat. Comparison with cyclosporin and (Val2)-dihydrocyclosporin effects in clinical, functional and histological studie (1992) (15)
The alternative cap-binding complex is required for antiviral defense in vivo (2019) (14)
IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity (2015) (14)
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice (2018) (14)
Hazards of Cyclosporine A Therapy and Recommendations for its Use (1988) (14)
An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates With Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection (2017) (14)
Inhibition of interleukin 4 receptor expression on human lymphoid cells by cyclosporin (1990) (13)
Mycobacterial Lipomannans Proinflammatory Cytokines by TLR 2-Independent-Negative Regulation of ( TLR 2 )-Dependent-Positive and Toll-Like Receptor 2 (2004) (13)
The immune response of the Chacma baboon to Bacille Calmette Guerin: development of a primate model for BCG-based vaccine research. (2005) (13)
Toll-like receptors: emerging targets of immunomodulation (2004) (13)
Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation (2012) (13)
Pathology induced by leukemia inhibitory factor. (1993) (13)
Long-Term Control of Mycobacterium bovis BCG Infection in the Absence of Toll-Like Receptors ( TLRs ) : Investigation of TLR 2-, TLR 6-, or TLR 2-TLR 4-Deficient Mice (2004) (13)
Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice. (1998) (13)
G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation. (2018) (13)
MHC antigens in interferon γ (IFNγ) receptor deficient mice: IFNγ-independent up-regulation of MHC class II in renal tubules (1995) (13)
MEK5/ERK5 signaling mediates IL‐4‐induced M2 macrophage differentiation through regulation of c‐Myc expression (2020) (13)
Quantitative fluorescence analysis of cyclosporine binding to human leukocytes. (1984) (12)
Unanticipated human toxicology of recombinant proteins. (1995) (12)
Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate--the marmoset. (1994) (12)
Glomerulonephritis in NZB/W mice: therapeutic effect of cyclosporine. (1986) (12)
Extrapolation of experimental safety data to humans: the interleukin-6 case. (1997) (12)
Use of transgenic animals to investigate drug hypersensitivity. (2001) (12)
Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses (2021) (12)
New cyclosporine derivative SDZ IMM 125: in vitro and in vivo pharmacologic effects and toxicologic evaluation. (1993) (12)
Synthetic triacylated lipid A derivative activates antigen presenting cells via the TLR4 pathway and promotes antigen-specific responses in vivo. (2006) (12)
In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice (2015) (12)
Effects of Nintedanib in an Animal Model of Liver Fibrosis (2020) (12)
CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells (2022) (11)
Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection (2019) (11)
Stingray venom activates IL-33 producing cardiomyocytes, but not mast cell, to promote acute neutrophil-mediated injury (2017) (11)
Hepatic steatosis in the absence of tumor necrosis factor in mice. (2005) (11)
Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy (2018) (11)
Osteomas in OF-1 mice: no alteration in biologic behavior during long-term treatment with cyclosporine. (1985) (11)
Inhibition of activation‐induced changes in the structure of the T cell interleukin‐7 receptor by cyclosporin A and FK506 (1993) (11)
Correction of the TNF-LTα-Deficient Phenotype by Bone Marrow Transplantation (1998) (11)
Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation. (1992) (11)
Lack of MyD88 Protects the Immunodeficient Host Against Fatal Lung Inflammation Triggered by the Opportunistic Bacteria Burkholderia cenocepacia1 (2009) (11)
Biochemical and morphological characterization of vascular and lymphocytic interleukin-4 receptors. (1996) (11)
Lipopolysaccharide-induced glomerulonephritis develops in the absence of interferon-gamma signaling. (1996) (11)
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure (2018) (10)
Phosphatidyl myo‐Inositol Mannosides Mimics Built on an Acyclic or Heterocyclic Core: Synthesis and Anti‐inflammatory Properties (2011) (10)
Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression (2019) (10)
Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis (2021) (10)
Complement C 5 Activation during Influenza A Infection in Mice Contributes to Neutrophil Recruitment and Lung Injury (2018) (10)
Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R (2017) (10)
Interleukin‐33 contributes to disease severity in Dengue virus infection in mice (2018) (10)
The interaction between a non-pathogenic and a pathogenic strain synergistically enhances extra-intestinal virulence in Escherichia coli. (2011) (10)
Unravelling the roles of innate lymphoid cells in cerebral malaria pathogenesis (2018) (9)
Cyclosporine nephrotoxicity. (1988) (9)
Exclusive expression of transmembrane TNF aggravates acute glomerulonephritis despite reduced leukocyte infiltration and inflammation. (2019) (9)
Cytokine knockout mice: possible application in toxicological research. (1995) (9)
The Effect of Metal Imbalances on Scrapie Neurodegeneration (2009) (9)
Reduced Local Growth and Spread but Preserved Pathogenicity of a ΔpurC Mycobacterium tuberculosis Auxotrophic Mutant in Gamma Interferon Receptor-Deficient Mice after Aerosol Infection (2005) (9)
The osteoprotective role of USP26 in coordinating bone formation and resorption (2022) (9)
Role of proinflammatory cytokines in a toxic response: application of cytokine knockout mice in toxicological research. (1995) (9)
Distribution and Activity of Calcineurin in Rat Tissues. Evidence for Post-transcriptional Regulation of Testis-specific Calcineurin B (1995) (9)
The viable motheaten (mev) mouse--a new model for arthritis. (1994) (9)
Natterin an aerolysin-like fish toxin drives IL-1β-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6. (2020) (9)
B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure (2020) (8)
Nilotinib combined with interleukin-2 mediates antitumor and immunological effects in a B16 melanoma model. (2014) (8)
Effects of cyclosporine on human T cell activation (1985) (8)
Characterization of interleukin-13 receptor in carcinoma cell lines and human blood cells and comparison with the interleukin-4 receptor. (1995) (8)
Molecular basis of carrageenan-induced cytokines production in macrophages (2020) (8)
Safety considerations of recombinant protein therapy: introductory comments. (1997) (8)
Safety of human recombinant proteins. (1997) (8)
Muc5b-deficient mice develop early histological lung abnormalities (2019) (8)
Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection (2017) (8)
Consequences of dietary manganese and copper imbalance on neuronal apoptosis in a murine model of scrapie (2010) (8)
Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis (2017) (8)
MHC antigens in interferon gamma (IFN gamma) receptor deficient mice: IFN gamma-dependent up-regulation of MHC class II in renal tubules. (1995) (8)
Cyclosporine Nephrotoxicity (1986) (8)
Secoeudesma sesquiterpenes lactone A alleviates inflammation and offers adjuvant protection in severe infection of carbapenem-resistant Klebsiella pneumoniae. (2020) (7)
Problems of cyclosporine localization in the renal tissue. (1986) (7)
Increased lymphocyte load of postcapillary venules in regional lymph nodes following stimulation with antigen -- isologous antibody complexes as compared with antigen alone. (1980) (7)
Th 17 Cells: Role in Inflammation and Autoimmune Disease (2009) (7)
IL–12–Dependent, IFN–γ–Independent Experimental Glomerulonephritis (2001) (7)
Cross-linking of human neutrophil surface proteins to iodinated interleukin 8 or neutrophil activating peptide-2 results in at least four separable proteins. (1993) (7)
Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation (2016) (7)
Corrigendum: The receptor NLRP3 is a transcriptional regulator of TH2 differentiation (2015) (7)
Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway (2018) (7)
Toll like receptor - potential drug targets in infectious disease. (2008) (6)
Effects of recombinant human interleukin 6 (rhIL-6) in marmosets (1994) (6)
Soluble Interferon-γ Receptor: A Therapeutically Useful Drug for Systemic Lupus Erythematosus (1994) (6)
IL-1 R 1 / MyD 88 Signaling Dependent Inflammation Is TLR 4 / MyD 88 and Cigarette Smoke-Induced Pulmonary and Isabelle Couillin (2007) (6)
Pathology induced by interleukin-6. (1992) (6)
Experimental Allergic Encephalomyelitis, Rat (1988) (6)
Experimental autoimmunity. (1986) (6)
A comparison of cyclosporine binding by cyclophilin and calmodulin. (1989) (6)
IL-12Rb2 Is Essential for the Development of Experimental Cerebral Malaria (2012) (6)
Histamine Scavenging Attenuates Endotoxin‐Induced Acute Lung Injury (2005) (6)
Histological assessment after different methods of reperfusion following liver transplantation. (2002) (6)
Glufosinate aerogenic exposure induces glutamate and IL-1 receptor dependent lung inflammation. (2016) (6)
ILC2s and Basophils Team Up to Orchestrate IL-33-Induced Atopic Dermatitis. (2019) (6)
ILC3-derived acetylcholine promotes protease-driven allergic lung pathology (2020) (5)
Preclinical safety studies with recombinant human interleukin 6 (rhil‐6) in the primate callithrix jacchus (marmoset): Comparison with studies in rats (1995) (5)
Immunodeficiency of Tumor Necrosis Factor and Lymphotoxin-α Double-Deficient Mice (1998) (5)
Innate type 1 immune response, but not IL-17 cells control tuberculosis infection (2020) (5)
Intracellular and nuclear localization of cyclosporine in peripheral blood mononuclear cells (1986) (5)
CD4 T cell- intrinsic STING signaling controls the differentiation and effector functions of T H 1 and T H 9 cells (2022) (5)
Cyclosporine A allows the expression of high affinity interleukin 2 binding sites on anti-T-cell antibody activated human T lymphocytes. (1987) (5)
Antibody-Independent Thrombocytopenia in Lactate Dehydrogenase-Elevating Virus-Infected Mice (2012) (5)
TGFb-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome (2012) (5)
Demonstration of ternary immunophilin-calcineurin complexes with the immunosuppressants cyclosporin and macrolide FK506. (1994) (5)
COMPARISON OF THE STRUCTURE OF THE MURINE INTERLEUKIN 2 (IL 2) RECEPTOR ON CYTOTOXIC AND HELPER T CELL LINES BY CHEMICAL CROSS‐LINKING OF 125I‐LABELED IL 2 (1988) (5)
Modulation of IFN-γ, TNF-α, IL-10 and IL-12 production by artesunate in mitogen treated splenocytes. (2009) (5)
Antigen-specific TGF- β -induced regulatory T cells but not natural Tregs ameliorate autoimmune arthritis by shifting the balance of Th17 toward Treg cells (2015) (4)
Brief review of the morphology of cyclosporin A nephropathy. (1987) (4)
Interferon‐γ is essential for the development of cerebral malaria (Vol. 27(4) 1997, pp 810‐815) (1998) (4)
Aryl hydrocarbon receptor (Ahr)‐dependent Il‐22 expression by type 3 innate lymphoid cells control of acute joint inflammation (2021) (4)
Mouse nidovirus LDV infection alleviates graft versus host disease and induces type I IFN‐dependent inhibition of dendritic cells and allo‐responsive T cells (2017) (4)
Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors (2022) (4)
Editorial: Ozone as a Driver of Lung Inflammation and Innate Immunity and as a Model for Lung Disease (2021) (4)
Cyclosporin A: Effects on the mouse thymus (1981) (3)
IL-18 Elicited Suppressor NK Cells with Immunoregulatory Functions (2008) (3)
Cyclosporine nephrotoxicity: pathogenetic factors and prevention. (1987) (3)
Nintedanib reduces bleomycin-induced lung inflammation and fibrosis in mice (2013) (3)
Silica‐related diseases in the modern world: A role for self‐DNA sensing in lung inflammatory diseases (2020) (3)
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments (2020) (3)
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin (2020) (3)
Arthropod‐Derived Protein EV131 Inhibits Histamine Action and Allergic Asthma (2005) (3)
Adjuvant activity on murine and human macrophages. (2010) (3)
Comparison of anti-IL-17A, IL-17F and TNF-α antibodies on host resistance to acute Mycobacterium tuberculosis infection in mice (2016) (3)
Soluble interferon-gamma receptor: a therapeutically useful drug for systemic lupus erythematosus. (1994) (3)
What Can the NZB/W Mice Teach us about the Treatment of SLE with Ciclosporin? (1985) (3)
The launch of the American Journal of Clinical and Experimental Immunology. (2012) (3)
Complement C5 inhibition attenuates lung inflammation in H1N1 influenza (2010) (3)
Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway (2022) (3)
Effect of the Dimethoate Administration on a Scrapie Murine Model (2008) (3)
MMP-9 Mediates Cross-Talk between Neutrophils and Endothelial Cells in Psoriasis. (2021) (3)
Effects of recombinant human interleukin 6 (rhIL-6) in marmosets (Callithrix jacchus) (1994) (2)
Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders (2022) (2)
The use of receptor assays for the rapid selection of an appropriate animale species for the preclinical investigations of human interleukins (1993) (2)
IL-12-dependent, INF-gamma-independent experimental glomerulonephritis. (2001) (2)
Evidence for shared receptor proteins for human interleukin-3 and granulocyte-macrophage colony-stimulating factor in the human M-07 cell line. (1993) (2)
Cyclosporine: Effects on human T lymphocyte activation and clinical application* (1984) (2)
NLRP3 Inflammasome Activation Leading to IL-1 – IL-17 Dependent Lung Inflammation and Fibrosis (2014) (2)
Autoantibody-Mediated Vasculitis Syndrome Through Tumor Necrosis Factor Production Upon Triggering Fc g Receptors (1999) (2)
Cyclosporine (Sandimmune) and wound healing (2004) (2)
B-cell activating factor regulates IL-1β- and IL-17A-mediated pulmonary fibrosis in mice (2015) (2)
Regulation of IL (Interleukin)-33 Production in Endothelial Cells via Kinase Activation and Fas/CD95 Upregulation (2020) (2)
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer (2020) (2)
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway (2017) (2)
Soluble TNFRp 75 regulates host protective immunity against Mycobacterium tuberculosis (2014) (2)
Complete ablation of tumor necrosis factor decreases the production of IgA, IgG, and IgM in experimental central nervous system tuberculosis (2020) (2)
Brief review of the morphology of ciclosporin nephropathy. (1987) (2)
IL-17A Family, Receptors, Proinflammatory Effects, and Production (2013) (2)
A brief review of modern toxicologic pathology in regulatory and explanatory toxicity studies of chemicals (2005) (2)
Infection in Mice tuberculosis Mycobacterium to Control Chronic Toll-Like Receptor 4 Expression Is Required (2002) (1)
MyD88 is essential for alveolar bone loss induced byAggregatibacter actinomycetemcomitansLPS in mice (2013) (1)
Mechanism of cyclosporin action: in vitro studies. (1987) (1)
Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter‐balanced by a strong Th2 bias (2021) (1)
Inflamatory response to cold plasma in normal skin (2010) (1)
Emphysema Elastase-Induced Lung Inflammation and IL-1 R 1 / MyD 88 Signaling Is Critical for (2009) (1)
Deletion of Mocos Induces Xanthinuria with Obstructive Nephropathy and Major Metabolic Disorders in Mice (2021) (1)
American Journal of Clinical and Experimental Immunology: Editorial Board (2012) e-Century Publishing Corporation. (2012) (1)
Inflammasome: IL-1/IL-17 Response in Lung Inflammation (2013) (1)
Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3 (2022) (1)
Brief review of the morphology of ciclosporin nephropathy. (1986) (1)
Effect of nintedanib on silica-induced lung inflammation and fibrosis in mice (2012) (1)
Interleukin-12-induced interferon-gamma inhibits hematopoiesis in vivo in mice. (1996) (1)
[Fatal tuberculosis despite adaptive immune response in the absence of MyD88]. (2005) (1)
[Current aspects in organ transplantation]. (1989) (1)
Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression (2020) (1)
Differential Regulation of Allergic Airway Inflammation by Acetylcholine (2022) (1)
MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection (2013) (1)
Toxoplasma gondii Intestinal {alpha}-Defensins by TLR9-Dependent Induction of (2010) (1)
Anti-CD3antibody-induced expression ofbothp55andp75chains ofthehighaffinity interleukin-2 receptor on humanT lymphocytes isinhibited bycyclosporin A (1990) (1)
A protective role of NOD2 on oxazolone-induced intestinal inflammation through IL-1-mediated signaling pathway. (2022) (1)
house dust mite-induced allergic lung inflammation (2015) (1)
IL-17 has a critical role to promote protection against Leishmania infantum infection (P3011) (2013) (1)
Role of Interferon-y in Interleukin 12-Induced Pathology in Mice (2007) (1)
Central Role of Th17 Cells in Adaptive Immune Responses (2013) (1)
Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients (2022) (1)
Uric Acid-Driven Th17 Differentiation (2011) (1)
NLRP6 negatively regulates type 2 immune responses in mice (2022) (1)
Role of TNF in Host Resistance to Tuberculosis Infection: Membrane TNF Is Sufficient to Control Acute Infection (2012) (1)
Rodent nutritional model of non-alcoholic steatohepatitus: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency. (2006) (1)
Can antiviral drug-resistant chikungunya viruses be transmitted by mosquitoes ? (2016) (1)
The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles (2014) (1)
Development and maturation of Langerhans cells, spleen and bone marrow dendritic cells in TNF-alpha/lymphotoxin-alpha double-deficient mice. (2005) (1)
IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin (2022) (1)
New Insights on the Role of Neutrophils in Ischemic Stroke (2019) (0)
997 Skin commensal bacteria drive the wound healing response by initiating pDC recruitment and activation in injured skin (2018) (0)
Macrophage Release of Tumour Necrosis Factor Directs Mesangial Cell Apoptosis and is Inhibited by Uptake of Apoptotic Cells; a Negative Feedback Loop in the Inflammatory Response (2002) (0)
Comprar Th 17 Cells: Role in Inflammation and Autoimmune Disease | Quesniaux, ValÃ©rie | 9783764386801 | Springer (2009) (0)
Extracellular HSP60 induces airway wall remodeling via Toll-Like-Receptors in mice (2022) (0)
Foxp3+ Regulatory T Cells: a Protagonist in the "Movie'' of Autoimmune (2011) (0)
Oral Supplementation With Selected Lactobacillus Acidophilus Triggers Antimicrobial Response, Activation of Innate Lymphoid Cells Type 3 And Improves Colitis (2021) (0)
Pathology induced by interleukins. Introduction. (1993) (0)
Molecular basis of carrageenan-induced cytokines production in macrophages (2020) (0)
Sophie Viaud of Cyclophosphamide The Intestinal Microbiota Modulates the Anticancer Immune Effects (2013) (0)
Dual effect of p38 MAP Kinase on TNF-dependent bronchoconstriction and TNF-independent neutrophil recruitment in LPS-induced ARDS. (2005) (0)
Mouse MRI and MR angiography at 9 . 4 T to study the role of PKC Θ protein in neurological complication of malaria (2010) (0)
P012 Control of mycobacterial infection in “humanized” TNF knock-in mice (2012) (0)
Phenotypic and functional characteristic of a newly identiﬁed CD 8 + Foxp 3 2 CD 103 + regulatory T cells (2014) (0)
ARYL HYDROCARBON RECEPTOR MEDIATES SMOKING-INDUCED RHEUMATOID ARTHRITIS EXACERBATION (2011) (0)
Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection (2019) (0)
TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis (2015) (0)
Acknowledgment to Reviewers of Toxics in 2021 (2022) (0)
OMCI in complex with leukotriene B4 (2012) (0)
Role of UNC93B1 in the MHC class I cross presentation pathway (2012) (0)
847w PAP/Reg3β Triggers IL-17-Dependent Neutrophil Recruitment and Intestinal Inflammation (2010) (0)
Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome (2015) (0)
Infection tuberculosis Mycobacterium Control of and C-Type Lectins for the Long-Term Recognition Receptors , Scavenger Receptors , Partial Redundancy of the Pattern (2010) (0)
Gerhard Zbinden, M.D. 1924-1993 (1993) (0)
NLRP3 Inflammasome Enhances Tumor Growth (2021) (0)
Tumournecrosis factor receptordistribution inhuman lymphoid tissue (1991) (0)
Inflammasome and Lung Pathologies (2011) (0)
Study of cerebral malaria using Plasmodium berghei and various knock-out mouse strains (1997) (0)
Contribution of IL-17 to the pulmonary inflammatory response (2009) (0)
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens (2018) (0)
S100A9 drives the chronification of psoriasiform inflammation by inducing IL-23/type 3 immunity. (2023) (0)
Mycobacterial phosphatidyl inositol mannosides negatively regulate host toll-like receptor 4, MYD88-dependent proinflammatory cytokines and trif-dependent co-stimulatory molecules expression. (2021) (0)
Correction: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation (2018) (0)
More transformations (1996) (0)
Diabetes Model Pathogenesis of Sepsis: Studies in a Murine Receptor Signaling in the 2 Histamine H (2013) (0)
Immune Complex-induced Acute Lung Bifunctional Lipocalin Ameliorates Murine Immunology : (2013) (0)
Resistance toCerebral Malaria inTumor Necrosis Factor-a/13-Defi cient MiceIsAssociated withaReduction ofIntercellular Adhesion Molecule-1 Up-Regulation andTHelper Type1 Response (1997) (0)
Analysis of cyclosporine binding T-lymphocyte subsets (1984) (0)
Protective role of the nucleic acid sensor STING in idiopathic pulmonary fibrosis (2022) (0)
Anisakis pegrefﬁi -Induced Airway Hyperresponsiveness Is Mediated by Gamma Interferon in the Absence of Interleukin-4 Receptor Alpha Responsiveness (cid:1) (2010) (0)
06.11 Anti-tnf-α vaccination protects from experimental arthritis without negatively affecting resistance to mycobacterium tuberculosis infection (2017) (0)
Role of UNC93B1, a chaperone molecule, in the MHC class I cross presentation pathway (2012) (0)
Immunity to mycobacterial infection (PP-061) (2010) (0)
Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension (2017) (0)
Correction: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation (2018) (0)
Effects of immunopharmacological compounds in the Lyme arthritis model using normal and SCID mice. (1998) (0)
A novel dendritic cell subset supporting the concept of tumor immunoediting: IFN producing Killer Dendritic cell (IKDC) (2006) (0)
Cyclosporine binding to cloned human T-lymphocytes (1984) (0)
Proteome reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients (2022) (0)
Immune Cells in Spleen and Mucosa + CD127 neg Production of IL-17 and IL-22 by CD3 TLR5 Signaling Stimulates the Innate (2010) (0)
Receptors γ Tumor Necrosis Factor Production Upon Triggering Fc Mast Cells Induce Autoantibody-Mediated Vasculitis Syndrome Through (2013) (0)
Acetylcholine producing innate type 2 and 3 lymphoid cells promote protease driven allergic lung inflammation (2022) (0)
Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes (2022) (0)
Oral supplementation with selected Lactobacillus acidophilus triggers IL-17-dependent innate defense response, activation of innate lymphoid cells type 3 and improves colitis (2022) (0)
Pathology induced by inflammatory cytokines. Introduction. (1993) (0)
IL-18Requires Inflammasome-Derived IL-1 and Uric Acid-Driven Th17 Differentiation (2011) (0)
[Benefits and risks of immunostimulation with interleukin 12]. (1996) (0)
ROLE OF TOLL-LIKE RECEPTORS SENSING AND CONTROL OFMYCOBACTERIAL INFECTION (2006) (0)
Janot et al. Eur J Immunol 2009 TLR5 and flagellin 3rd (2013) (0)
Evolution of Cyclosporin Nephrotoxicity (1991) (0)
Microenvironment and Immunology SOCS 3 Transactivation by PPAR g Prevents IL-17 – Driven Cancer Growth (2013) (0)
TNF-Deficient Mice Reactivation of Latent Tuberculosis Infection (2003) (0)
GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection (2018) (0)
Quesniaux / Ryffel / Di Padova : Th 17 Cells : Role in Inflammation and Autoimmune Disease Summary (2017) (0)
Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses (2022) (0)
The anti-inflammatory extract from leaves of Isatis tinctoria (Ze 550) inhibits dose dependently the allergen induced airway-response in sensitized mice (2007) (0)
TLR 6-, or TLR 2-TLR 4-Deficient Mice Receptors ( TLRs ) : Investigation of TLR 2-, BCG Infection in the Absence of Toll-Like Mycobacterium bovis Long-Term Control of (2004) (0)
STING-dependent sensing of self-DNA drives silica-induced lung inflammation (2018) (0)
The PPAR target gene CD36 is a rate limiting factor for the sensing of gram positive S-aureus in vascular smooth muscle cells but not in macrophages (2008) (0)
Control Polymicrobial Sepsis IL-17 Receptor Signaling Is Required to (0)
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice (2018) (0)
Involvement of interleukin-1 receptor (IL1R1) and myeloid differentiation primary response gene 88 (MyD88) signaling in pulmonary hypertension (PH) (2015) (0)
PKC theta controls ILC 2 and Th 2 responses to house dust mite allergen 1 (2016) (0)
Suppressing Innate Immunity to Infection Attenuate Experimental Arthritis without Dominant-Negative Inhibitors of Soluble TNF (2007) (0)
Abstract 16825: Macrophage Sensing of Lps in vivo is Not Required for the Induction of Systemic Inflammation (2010) (0)
Mice Advantage in Transgenic Lipopolysaccharide and Provides a 4 Amplifies the Host Response to Overexpression of Toll-Like Receptor (2010) (0)
TGF-β-induced CD4+ regulatory T cells but not nTregs ameliorate autoimmune arthritis by shifting the balance between Tregs and Th17 cells In vivo (179.14) (2012) (0)
Crucial function for the interferon-gamma receptor in the control of Plasmodium chabaudi malaria (1997) (0)
Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice (2005) (0)
MyD 88 Dependent Infection Is Trypanosoma brucei following a The Induction of a Type 1 Immune Response (2005) (0)
Sensing bacterial viability for host defense (2011) (0)
Phenotypic and functional characteristic of a newly identified CD 8 + Foxp 3 2 CD 103 + regulatory T cells (2014) (0)
ROLE OF TNF AND ICAM-1 IN THE DEVELOPMENT OF EXPERIMENTAL MURINE CEREBRAL MALARIA (1998) (0)
Bifunctional lipocalin inhibitor of C5 and leukotriene B4 is protective in experimental immune complex alveolitis (2010) (0)
OMCI in complex with palmitoleic acid (2012) (0)
Inflammatory cytokines, receptors, and disease (1993) (0)
P011 TNF inhibition combined with chemotherapy for experimental tuberculosis improves pulmonary bacterial clearance and reduces pathology (2012) (0)
Interleukins and hemopoietic growth factors (1993) (0)
Comment on: Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-lRl/MyD88 Signaling Dependent. Authors' reply (2008) (0)
Erratum to: Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway (2010) (0)
CD 14-Deficient Mice Lipopolysaccharide-Binding Protein or Is Delayed in Salmonella Infection with Neutrophil Influx in Response to a Peritoneal (2002) (0)
Lupus-Prone ( NZB × NZW ) F Production and Glomerulonephritis in Receptor Deletion Prevents Autoantibody (1998) (0)
Small-molecule P2RX7 activator sensitizes tumor to immunotherapy and vaccinates mouse against tumor re-challenge (2020) (0)
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice (2020) (0)
[T lymphocyte activation and its inhibition by cyclosporin A]. (1987) (0)
Effector IFN-Producing Killer Dendritic Cells -Presentation of IL-15 Dictates Trans (0)
A5.11 Vaccination against TNF and side effects in listeria infection model (2015) (0)
Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure (2023) (0)
352 Commensal microbiota trigger type I IFN-dependent innate wound repair responses in injured skin (2019) (0)
Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice (2018) (0)
NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype (2023) (0)
Burkholderia cenocepacia Triggered by the Opportunistic Bacteria Host Against Fatal Lung Inflammation Lack of MyD88 Protects the Immunodeficient (2009) (0)
Pathology induced by hematopoietic growth factors. Introduction. (1993) (0)
Foxp3+ Regulatory T Cells: a Protagonist in the “Movie’’ of Autoimmune Diseases? (2011) (0)
TGF-{beta}-induced CD4+ regulatory T cells but not nTregs ameliorate autoimmune arthritis by shifting the balance between Tregs and Th17 cells In vivo (2012) (0)
[Discovery of novel immunosuppressants in vitro] (1991) (0)
Savers, Amélie and Rasid, Orhan and Parlato, Marianna and Brock, Matthias and Jouvion, Gregory and Ryffel, Bernhard and Cavaillon, Jean-Marc and Eberl, Gerard and Ibrahim-Granet, Oumaïma (2016) Infection- mediated priming of phagocytes protects against lethal secondary Aspergillus fumigatus (2017) (0)
Identification of determinants for malaria pathogenesis using experimental mouse models (1998) (0)
Rapid Communication Tumor Necrosis Factor Receptors in Lymphoid Tissues and Lymphomas Source and Site of Action of 7 Factor Alpha (2007) (0)
TLR-dependent positive and TLR-independent negative regulation of proinflammatory cytokines by mycobacterial lipomannans (2004) (0)
Respiratory Distress Syndrome Lipopolysaccharide-Induced Acute TNF-Independent Neutrophil Recruitment in TNF-Dependent Bronchoconstriction and Dual Effects of p 38 MAPK on (2005) (0)
Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling (2021) (0)
Inflammatory Response to Inhaled Endotoxin Required for MyD 88-Dependent Pulmonary Both Hemopoietic and Resident Cells Are Isabelle (2005) (0)
Brucella melitensis with Response upon Secondary Infection Both Necessary for a Fully Protective Th1 Cells Are + Humoral Immunity and CD4 (2014) (0)
Th17/Th1 axis polarization is mediated by IL-1 receptor in type 1 diabetes murine model (123.13) (2012) (0)
Hepatic Stellate Cell Activation Pathogenesis of Liver Fibrosis through IL-17 A Plays a Critical Role in the Ryffel and Beicheng (2013) (0)
in NK cytoskeleton organization and activation Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 (2013) (0)
Development and maturation of Langerhans cells, spleen and bone marrow dendritic cells in TNF-α/lymphotoxin-α double-deficient mice (2005) (0)
Sensing bacterial viability for host defense (116.23) (2011) (0)
Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation (2018) (0)
Effects of recombinant human interleukin 6 (rhlL-6) on common laboratory values in marmosets (1994) (0)
Th17, Th22 and regulatory T cells are essential for controlling parasite burden and mucosal inflammation during Toxoplasma gondii infection (43.11) (2012) (0)
Emploi pharmaceutique de (NVA)2-cyclosporine (1985) (0)
Tumor Necrosis Factor Alpha-Mediated Toxic Shock in Trypanosoma cruzi -Infected Interleukin 10-Deﬁcient Mice (2000) (0)
The use of cyclosporins (1985) (0)
Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells (2017) (0)
C5a is produced during influenza a infection and contributes to neutrophil recruitment and lung pathology (2011) (0)
Stingray venom activates IL-33 producing cardiomyocytes, but not mast cell, to promote acute neutrophil-mediated injury (2017) (0)
Gingiva-derived mesenchymal stem cells-mediated therapeutic intervention for experimental arthritis through Foxp3+ Tregs (56.7) (2012) (0)
Conclusions of the Satellite Sympsoium of the Eurotox '91 Congress on (1992) (0)
New pharmaceutical application of (nva) (arrow up) 2 (arrow up) - and dihydro- (val) (arrow up) 2 (arrow high) -cyclosporin (1985) (0)
Infection tuberculosis Mycobacterium Innate Response to Essential Component of MyD 88-Dependent IL-1 Receptor-Mediated Signal Is an Quesniaux (2007) (0)
Pharmaceutical application of (NVA) 2-cyclosporine. (1985) (0)
IL-33 signalling in liver immune cells enhances drug-induced liver injury and inflammation (2017) (0)

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