Bernhard

Bernhard Witkop

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American-German organic chemist

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Bernhard Witkop
Chemistry
#2149
World Rank
#3014
Historical Rank
chemistry Degrees
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  • Chemistry

Why Is Bernhard Witkop Influential?

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According to Wikipedia, Bernhard Witkop was a German-born American organic chemist who worked for the National Institutes of Health for 37 years. During those years, Witkop – along with his recruit, John Daly, and others – discovered the NIH shift, a term describing the movement of hydrogen, deuterium or tritium to adjacent carbons on aromatic rings during oxidation, a process key in developing many therapies. He also helped to develop selective methods for the non-enzymatic cleavage of proteins, which enabled the sequencing of amino acids in proteins as large as immunoglobulin, a method later used in the production of human insulin.

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