Betty Diamond

Q: What Schools Are Affiliated With Betty Diamond

Betty Diamond is affiliated with the following schools: Albert Einstein College of Medicine, Columbia University, Harvard University, Radcliffe College

Betty Diamond's AcademicInfluence.com Rankings

Betty Diamond

Biology

#5107

World Rank

#7512

Historical Rank

#1814

USA Rank

Immunology

#246

World Rank

#256

Historical Rank

#64

USA Rank

biology Degrees

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Biology

Betty Diamond's Degrees

Doctorate Medicine Albert Einstein College of Medicine
PhD Immunology Albert Einstein College of Medicine

Why Is Betty Diamond Influential?

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According to Wikipedia, Betty Diamond is an American physician and researcher. She is director of the Institute of Molecular Medicine at Northwell Health's Feinstein Institute for Medical Research in Manhasset, NY. She was elected a member of the National Academy of Sciences in 2022.

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Betty Diamond's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The gut microbiota influences blood-brain barrier permeability in mice (2014) (1387)
Autoimmune diseases (2000) (1178)
Combined Oral Contraceptives in Women With Systemic Lupus Erythematosus (2005) (958)
2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (2019) (936)
A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus (2001) (708)
Estrogen alters thresholds for B cell apoptosis and activation. (2002) (473)
2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus (2019) (419)
Cognition and immunity; antibody impairs memory. (2004) (396)
Human lupus autoantibodies against NMDA receptors mediate cognitive impairment (2006) (386)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (369)
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. (1984) (318)
Cutting Edge: Expansion and Activation of A Population of Autoreactive Marginal Zone B Cells in a Model of Estrogen-Induced Lupus (2001) (289)
Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95. (2008) (273)
Immunity and behavior: antibodies alter emotion. (2006) (273)
Revisiting and revising suppressor T cells. (1992) (255)
Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells. (2000) (253)
Anti-N-methyl-D-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus. (2006) (251)
Selective dysregulation of the FcγIIB receptor on memory B cells in SLE (2006) (248)
The role of somatic mutation in the pathogenic anti-DNA response. (1992) (246)
Losing your nerves? Maybe it's the antibodies (2009) (237)
Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease. (1996) (236)
Similarities and differences between selective and nonselective BAFF blockade in murine SLE. (2006) (219)
Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity. (2015) (217)
Treatment of Lupus Nephritis With Abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study (2014) (212)
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development (2009) (201)
Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study. (2010) (198)
Immunization with a Peptide Surrogate for Double-stranded DNA (dsDNA) Induces Autoantibody Production and Renal Immunoglobulin Deposition (1998) (193)
HMGB1 Mediates Cognitive Impairment in Sepsis Survivors (2012) (187)
Peptide inhibition of glomerular deposition of an anti-DNA antibody. (1997) (187)
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms (2010) (178)
Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice (2013) (178)
Serum and Cerebrospinal Fluid Autoantibodies in Patients with Neuropsychiatric Lupus Erythematosus. Implications for Diagnosis and Pathogenesis (2008) (171)
The Impact of Vitamin D on Dendritic Cell Function in Patients with Systemic Lupus Erythematosus (2010) (166)
Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity (1995) (157)
Current and novel therapeutics in the treatment of systemic lupus erythematosus. (2011) (153)
C1q limits dendritic cell differentiation and activation by engaging LAIR-1 (2012) (150)
Abatacept for lupus nephritis: alternative definitions of complete response support conflicting conclusions. (2012) (149)
Prolactin modulates the naive B cell repertoire. (2003) (147)
Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus (2009) (144)
Mechanism of Action of Transmembrane Activator and Calcium Modulator Ligand Interactor-Ig in Murine Systemic Lupus Erythematosus1 (2004) (143)
Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder (2013) (142)
A new Fc receptor on mouse macrophages binding IgG3 (1981) (139)
Brain-reactive antibodies and disease. (2013) (134)
Mutational analysis of an autoantibody: differential binding and pathogenicity (1994) (134)
B Cell Selection and Susceptibility to Autoimmunity (2005) (130)
The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial. (2006) (129)
Human Double-Negative T Cells in Systemic Lupus Erythematosus Provide Help for IgG and Are Restricted by CD1c1 (2000) (125)
The production and characterization of monoclonal antibodies to a human colonic antigen associated with ulcerative colitis: cellular localization of the antigen by using the monoclonal antibody. (1987) (123)
PD-1hi CXCR5- T peripheral helper cells promote B cells responses in lupus via MAF and IL-21. (2019) (118)
Hormonal Regulation of B Cell Development: 17β-Estradiol Impairs Negative Selection of High-Affinity DNA-Reactive B Cells at More Than One Developmental Checkpoint1 (2006) (113)
Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus. (1983) (113)
C1q and HMGB1 reciprocally regulate human macrophage polarization. (2016) (105)
CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B cell signaling and activation (2012) (105)
Bromocriptine restores tolerance in estrogen-treated mice. (2000) (104)
Fusion of mouse myeloma and spleen cells. (1978) (104)
The Fc receptors of primary and cultured phagocytic cells studied with homogeneous antibodies. (1978) (102)
Sex hormones and SLE: influencing the fate of autoreactive B cells. (2006) (102)
Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors (2018) (99)
Hormonal modulation of B cell development and repertoire selection. (2005) (98)
Induction of tolerance to an IgG autoantibody. (1992) (96)
Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes. (1990) (96)
The role of B cells in lupus pathogenesis. (2010) (94)
A novel class of anti-DNA antibodies identified in BALB/c mice (1991) (91)
Cognitive and neurologic deficits in the MRL/lpr mouse: a clinicopathologic study. (1993) (90)
Differential Roles of Estrogen Receptors α and β in Control of B-Cell Maturation and Selection (2011) (88)
Monoclonal Antibodies: A New Technology for Producing Serologic Reagents (1981) (87)
Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus (2018) (84)
Tolerogenic function of Blimp-1 in dendritic cells (2012) (81)
Regulation of dendritic cell activation by microRNA let-7c and BLIMP1. (2013) (81)
Comparison of alternative primary outcome measures for use in lupus nephritis clinical trials. (2013) (80)
The intersection of COVID-19 and autoimmunity. (2021) (79)
Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype (1991) (79)
Hormonal regulation of B-cell function and systemic lupus erythematosus (2008) (78)
Randomized, Double‐Blind, Placebo‐Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus (2015) (78)
Identification of an antigen-specific B cell population. (2003) (77)
Caspr2-reactive antibody cloned from a mother of an ASD child mediates an ASD-like phenotype in mice (2016) (77)
Molecular mimicry between bacterial and self antigen in a patient with systemic lupus erythematosus (1999) (77)
Prolactin as a modulator of B cell function: implications for SLE. (2004) (77)
Lack of allelic exclusion permits autoreactive B cells to escape deletion. (1994) (74)
Light Chain Usage in Anti–double-stranded DNA B Cell Subsets: Role in Cell Fate Determination (1997) (74)
Expansion and Hyperactivity of CD1d-Restricted NKT Cells during the Progression of Systemic Lupus Erythematosus in (New Zealand Black × New Zealand White)F1 Mice1 (2005) (73)
Polyreactive autoantibodies in systemic lupus erythematosus have pathogenic potential. (2009) (73)
Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis. (1998) (73)
HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6Chigh inflammatory monocytes in murine sepsis survivors (2013) (72)
Use of computerized assessment to predict neuropsychological functioning and emotional distress in patients with systemic lupus erythematosus. (2006) (72)
Phase III, multicentre, randomised, double-blind, placebo-controlled, 104-week study of subcutaneous belimumab administered in combination with rituximab in adults with systemic lupus erythematosus (SLE): BLISS-BELIEVE study protocol (2019) (71)
Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor (2015) (70)
Repertoire of Human Antibodies against the Polysaccharide Capsule of Streptococcus pneumoniaeSerotype 6B (1999) (70)
Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue (2018) (69)
Requirement for cyclin D3 in germinal center formation and function (2010) (66)
Molecular Analysis of the Autoantibody Response in Peptide-Induced Autoimmunity1 (2000) (66)
All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes. (1980) (66)
Phase II Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis (2020) (65)
Familial systemic lupus erythematosus. Presence of a cross-reactive idiotype in healthy family members. (1985) (65)
The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody. (1996) (64)
Block and tackle: CTLA4Ig takes on lupus (2005) (64)
Cross-reactive antibodies have both protective and pathogenic potential. (1995) (63)
Neural Signaling in the Spleen Controls B-Cell Responses to Blood-Borne Antigen (2012) (63)
ICER/CREM‐mediated transcriptional attenuation of IL‐2 and its role in suppression by regulatory T cells (2007) (62)
It takes guts to grow a brain (2011) (61)
The generation of macrophage-like cell lines by transfection with SV40 origin defective DNA. (1984) (61)
Receptor editing in peripheral B cell tolerance. (2005) (60)
Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes. (1993) (60)
Fundamental role of C1q in autoimmunity and inflammation (2015) (59)
Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus (2021) (58)
Generation of a fusion partner to sample the repertoire of splenic B cells destined for apoptosis. (1994) (58)
A model for lupus brain disease (2012) (58)
Transcriptional and functional profiling of human intestinal dendritic cells reveals conserved specialization and a role for Bcl-6 and Blimp-1 in terminal subset differentiation (2013) (56)
The generation of human monocyte/macrophage cell lines (1983) (56)
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase (2016) (55)
Immunoglobulin isotype determines pathogenicity in antibody-mediated myocarditis in naïve mice. (2000) (55)
Evidence for immunoglobulin Fc receptor-mediated prostaglandin2 and platelet-activating factor formation by cultured rat mesangial cells. (1988) (55)
Follicular Helper T Cells in Systemic Lupus Erythematosus (2018) (54)
Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors (2017) (54)
Mouse placental macrophages have a decreased ability to present antigen. (1993) (53)
T-Cell-Dependent Antibody Response to the Dominant Epitope of Streptococcal Polysaccharide,N-Acetyl-Glucosamine, Is Cross-Reactive with Cardiac Myosin (2000) (53)
Tamoxifen Blocks Estrogen-Induced B Cell Maturation but Not Survival1 (2005) (53)
HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis (2019) (52)
C1q-Mediated Repression of Human Monocytes Is Regulated by Leukocyte-Associated Ig-Like Receptor 1 (LAIR-1) (2014) (52)
Comparison of DNA antibody idiotypes in human sera: an international collaborative study of 19 idiotypes from 11 different laboratories. (1990) (52)
Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial (2020) (51)
Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity (2011) (51)
Idiotypic analysis of myeloma proteins: anti-DNA activity of monoclonal immunoglobulins bearing an SLE idiotype is more common in IgG than IgM antibodies. (1987) (51)
Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry (2016) (51)
Lupus-specific antibodies reveal an altered pattern of somatic mutation. (1997) (50)
Cutting Edge: Hormonal Milieu, Not Antigenic Specificity, Determines the Mature Phenotype of Autoreactive B Cells1 (2006) (50)
Increased Cathepsin S in Prdm1−/− dendritic cells alters TFH repertoire and contributes to lupus (2017) (50)
Antibodies elicited by pneumococcal antigens bear an anti-DNA--associated idiotype. (1991) (49)
Characterization of anti‐DNA B cells that escape negative selection (1999) (47)
Moving towards a cure: blocking pathogenic antibodies in systemic lupus erythematosus (2011) (47)
Female mouse fetal loss mediated by maternal autoantibody (2012) (47)
Antibodies as Mediators of Brain Pathology. (2015) (46)
B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice. (2008) (46)
The anti-DNA-associated idiotype 8.12 is encoded by the V lambda II gene family and maps to the vicinity of L chain CDR1. (1992) (46)
Multicriteria decision analysis process to develop new classification criteria for systemic lupus erythematosus (2019) (45)
A cross-reactive idiotype on anti-DNA antibodies defines a H chain determinant present almost exclusively on IgG antibodies. (1989) (45)
Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear (2019) (45)
Pulse steroids: how much is enough? (2006) (45)
Glutamate receptor biology and its clinical significance in neuropsychiatric systemic lupus erythematosus. (2010) (45)
Metabolic and microstructural alterations in the SLE brain correlate with cognitive impairment. (2019) (44)
IgG1 and IgG2b share the Fc receptor on mouse macrophages. (1980) (44)
Tolerogenic function of Blimp-1 in dendritic cells (2011) (44)
HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors (2015) (44)
The role of somatic mutation of immunoglobulin genes in autoimmunity. (1987) (43)
Pathogenic Autoantibodies in Systemic Lupus Erythematosus Are Derived from Both Self-Reactive and Non-Self-Reactive B Cells (2008) (43)
Immunity and acquired alterations in cognition and emotion: lessons from SLE. (2006) (43)
Phenotypic Characterization of Autoreactive B Cells—Checkpoints of B Cell Tolerance in Patients with Systemic Lupus Erythematosus (2009) (43)
Neurocognitive impairment in childhood‐onset systemic lupus erythematosus: Measurement issues in diagnosis (2011) (42)
Understanding the Antibody Repertoire in Neuropsychiatric Systemic Lupus Erythematosus and Neuromyelitis Optica Spectrum Disorder (2018) (42)
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus (2001) (42)
Genetic control of autoimmune myocarditis mediated by myosin-specific antibodies (1999) (42)
Autoimmunity in heart disease: mechanisms and genetic susceptibility. (1996) (42)
Detection of masked anti-DNA antibodies in lupus sera by a monoclonal anti-idiotype. (1984) (40)
Bcl‐2 leads to expression of anti‐DNA B cells but no nephritis: a model for a clinical subset (1999) (40)
A monoclonal antibody to a cross-reactive idiotype on cationic human anti-DNA antibodies expressing lambda light chains: a new reagent to identify a potentially differential pathogenic subset. (1987) (40)
The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development. (2012) (40)
High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation (2018) (39)
The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment (2017) (39)
Brain metabolism and autoantibody titres predict functional impairment in systemic lupus erythematosus (2015) (39)
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients (2015) (38)
Autoimmune Disease–Associated Haplotypes of BLK Exhibit Lowered Thresholds for B Cell Activation and Expansion of Ig Class‐Switched B Cells (2015) (38)
Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression (2017) (38)
Regulatory T cell‐mediated suppression: potential role of ICER (2007) (38)
Studies on the structure, regulation, and pathogenic potential of anti-dsDNA antibodies. (1997) (37)
Alterations in Blood-Brain Barrier Permeability in Patients with Systemic Lupus Erythematosus (2019) (37)
Differences in Regional Brain Activation Patterns Assessed by Functional Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus Stratified by Disease Duration (2011) (37)
Modulation of tolerogenic dendritic cells and autoimmunity. (2015) (36)
Autoimmune myocarditis does not require B cells for antigen presentation. (1999) (35)
Design and application of single-cell RNA sequencing to study kidney immune cells in lupus nephritis (2019) (35)
Integrated urine proteomics and renal single-cell genomics identify an interferon-γ response gradient in lupus nephritis. (2020) (35)
Staphylococcus aureus infection of human endothelial cells potentiates Fc receptor expression. (1990) (34)
Pathogenic anti-DNA antibodies in SLE: idiotypic families and genetic origins. (1990) (34)
Increased IL-12 inhibits B cells' differentiation to germinal center cells and promotes differentiation to short-lived plasmablasts (2008) (33)
Fc receptors on cultured myeloma and hybridoma cells. (1985) (33)
Lupus and the central nervous system (2008) (33)
Maternal antibodies and developing blood–brain barrier (2015) (32)
Performance of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in early disease, across sexes and ethnicities (2020) (32)
Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: clues to their origin. (2001) (32)
HMGB1 in Systemic Lupus Erythematosus (2020) (31)
Site of binding of mouse IgG2b to the Fc receptor on mouse macrophages (1979) (30)
Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory (2020) (30)
Intranasal immunization with protein-linked phosphorylcholine protects mice against a lethal intranasal challenge with streptococcus pneumoniae. (2000) (30)
The Naive B Cell Repertoire Predisposes to Antigen-Induced Systemic Lupus Erythematosus (2003) (29)
Mapping the immunological homunculus (2011) (29)
The function of hematopoietic stem cells is altered by both genetic and inflammatory factors in lupus mice. (2013) (29)
B-cell biology. (2004) (28)
Enhanced Selection of High Affinity DNA-Reactive B Cells Following Cyclophosphamide Treatment in Mice (2009) (28)
Molecular mimicry: anti-DNA antibodies bind microbial and nonnucleic acid self-antigens. (2005) (28)
ORIGINS OF ANTI-DNA ANTIBODIES (1986) (28)
Loss of an IgG plasma cell checkpoint in patients with lupus (2019) (28)
Molecular signatures in systemic lupus erythematosus: distinction between disease flare and infection (2016) (27)
Studies of human polyclonal and monoclonal antibodies binding to lupus autoantigens and cross-reactive antigens. (2003) (27)
Structural modification of DNA—a therapeutic option in SLE? (2011) (27)
Preferential expression of the systemic lupus erythematosus-associated idiotype 8.12 in sera containing monoclonal immunoglobulins. (1987) (26)
Suppression of anti-DNA antibody synthesis in vitro by a cross-reactive antiidiotypic antibody. (1987) (26)
Cognitive Dysfunction in Systemic Lupus Erythematosus: A Case for Initiating Trials (2019) (25)
Hormonal milieu at time of B cell activation controls duration of autoantibody response. (2014) (25)
European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance (2021) (25)
On the track of neuropsychiatric lupus. (2003) (25)
Maternal lupus and congenital cortical impairment (2008) (25)
Generation and maturation of bone marrow-derived DCs under serum-free conditions. (2007) (24)
Antibodies and the Brain: Lessons from Lupus (2010) (24)
Anti-DNA antibodies cross-react with C1q. (2013) (24)
Targeting DEC-205−DCIR2+ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis (2018) (24)
A Monoclonal Antibody That Recognizes Anti‐DNA Antibodies in Patients with Systemic Lupus (1983) (24)
Generation and analysis of clonal IgM- and IgG-producing human B cell lines expressing an anti-DNA-associated idiotype. (1991) (23)
Idiotype-mediated intervention in systemic lupus erythematosus. (1990) (23)
Cutting Edge: Lupus Susceptibility Interval Sle3/5 Confers Responsiveness to Prolactin in C57BL/6 Mice1 (2006) (23)
Commentary: Crossing the Atlantic: The Euro‐Lupus Nephritis Regimen in North America (2015) (23)
DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways (2018) (23)
Selective regulation of autoreactive B cells by FcgammaRIIB. (2009) (23)
Systemic lupus erythematosus in males: analysis of clinical and laboratory features. (1992) (23)
HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes (2021) (23)
GWAS implicates a role for quantitative immune traits and threshold effects in risk for human autoimmune disorders. (2012) (22)
Development of a monoclonal antibody specifically reactive to gastrointestinal goblet cells. (1987) (22)
Identification of DNA-reactive B cells in patients with systemic lupus erythematosus. (2008) (22)
Crossreactive B cells are present during a primary but not secondary response in BALB/c mice expressing a bcl-2 transgene. (1999) (22)
The J744.2 cell line presents antigen in an I region restricted manner. (1983) (22)
Regional brain metabolism in a murine systemic lupus erythematosus model (2014) (22)
Constitutive Vagus Nerve Activation Modulates Immune Suppression in Sepsis Survivors (2018) (21)
Functional analysis of cloned macrophage hybridomas. VII. Modulation of suppressor T cell-inducing activity. (1989) (21)
Peptide Mimic of Phosphorylcholine, a Dominant Epitope Found on Streptococcus pneumoniae (2000) (20)
The renin–angiotensin system: An integrated view of lung disease and coagulopathy in COVID-19 and therapeutic implications (2020) (20)
Dynamic Contrast-Enhanced MRI Reveals Unique Blood-Brain Barrier Permeability Characteristics in the Hippocampus in the Normal Brain (2019) (20)
IgG+, CD5+ human chronic lymphocytic leukemia B cells. Production of IgG antibodies that exhibit diminished autoreactivity and IgG subclass skewing. (1994) (20)
DNA-reactive B cells in lupus. (2016) (20)
Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain. (1990) (19)
Antigen Is Required for Maturation and Activation of Pathogenic Anti-DNA Antibodies and Systemic Inflammation (2011) (19)
Estrogen upregulates Bcl-2 and blocks tolerance induction of naı̈ve B cells (2000) (19)
Aspects of CNS lupus: mouse models of anti-NMDA receptor antibody mediated reactivity. (2012) (19)
Functional analysis of cloned macrophage hybridomas. VI. Differential ability to induce immunity or suppression. (1988) (19)
The immune tolerance network and rheumatic disease: immune tolerance comes to the clinic. (2001) (18)
Overexpression of bcl-2 alters usage of mutational hot spots in germinal center B cells. (1997) (18)
Neuropsychiatric systemic lupus erythematosus reconsidered (2008) (18)
Novel therapeutics for systemic lupus erythematosus (2006) (17)
Therapeutics to block autoantibody initiation and propagation in systemic lupus erythematosus and rheumatoid arthritis (2015) (17)
Molecular analysis of the human immunoglobulin V lambda II gene family. (1994) (17)
Lessons from an anti-DNA autoantibody. (2011) (17)
FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis (2018) (17)
Meant to B: B cells as a therapeutic target in systemic lupus erythematosus. (2021) (16)
General Features of Autoimmune Disease (2020) (16)
A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins. (2016) (16)
Effects of immunoglobulin structure on Fc receptor binding: a mouse myeloma variant immunoglobulin with a gamma 2b-gamma 2a hybrid heavy chain having a complete gamma 2a Fc region fails to bind to gamma 2a Fc receptors on mouse macrophages. (1982) (16)
Characterization of two human anti-DNA antibodies bearing the pathogenic idiotype 8.12. (1993) (16)
Expression of Blimp-1 in Dendritic Cells Modulates the Innate Inflammatory Response in Dextran Sodium Sulfate-Induced Colitis (2014) (16)
Blood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus Nerve (2016) (16)
Balancing diversity and tolerance (2005) (16)
IL-6 contributes to an immune tolerance checkpoint in post germinal center B cells. (2012) (15)
The molecular origin of anti-DNA antibodies. (1989) (15)
SLE‐associated risk factors affect DC function (2015) (15)
Genetic approaches to the mechanism of macrophage functions. (1978) (15)
Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele. (2017) (15)
Maternal Antibody and ASD: Clinical Data and Animal Models (2019) (15)
Analysis of the VKI Family: Germline Genes from an SLE Patient and Expressed Autoantibodies (1995) (15)
Site of binding of IgG2b and IgG2a by mouse macrophage Fc receptors by using cyanogen bromide fragments. (1985) (14)
Immunoglobulin gene sequence analysis of anti-cardiolipin and anti-cardiolipin idiotype (H3) human monoclonal antibodies. (1995) (14)
Randomized , Double-Blind , Placebo-Controlled Trial of the Effect of Vitamin D 3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus (2018) (14)
Patterns of ANA+ B cells for SLE patient stratification. (2019) (14)
A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network (2018) (14)
Assessing cognitive impairment in SLE: examining relationships between resting glucose metabolism and anti-NMDAR antibodies with navigational performance (2019) (13)
Characterization of the human Ig V lambda II gene family and analysis of V lambda II and C lambda polymorphism in systemic lupus erythematosus. (1991) (13)
XBP 1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development (2009) (13)
Anti-DNA antibodies secreted by peripheral B cells of lupus patients have both normal and lupus-specific features. (1993) (13)
Lineage-Specific Functionality of an Interferon Regulatory Factor 5 Lupus Risk Haplotype: Lack of B Cell Intrinsic Effects (2018) (13)
Some observations on the in vitro reactivity of lymphoid subpopulations. (1974) (13)
Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons (2018) (13)
Inflammatory profile in the cerebrospinal fluid of patients with central neuropsychiatric lupus, with and without associated factors. (2009) (12)
Urine Proteomics and Renal Single‐Cell Transcriptomics Implicate Interleukin‐16 in Lupus Nephritis (2021) (12)
Fate determination of mature autoreactive B cells. (2013) (12)
Arthritis and antinuclear antibodies (ANA) with inherited deficiency of the sixth component of complement (C6). (1986) (12)
Regulating the isotypic and idiotypic profile of an anti-PC antibody response: lessons from peptide mimics. (2002) (12)
Guidelines for assessing immunocompetency in clinical trials for autoimmune diseases. (2007) (12)
The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits (2015) (12)
Antibody inhibition of suppressor cell induction. (1987) (12)
Autoantibodies that bind glomeruli: cross-reactivity with bacterial antigen. (2005) (12)
Speculations on the immunogenicity of self proteins. (2003) (11)
Persistence of partially functional double-stranded (ds) DNA binding B cells in mice transgenic for the IgM heavy chain of an anti-dsDNA antibody. (2002) (11)
Plasmacytomas and Hybridomas (1980) (11)
Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus (2018) (11)
The immune cell landscape in kidneys of lupus nephritis patients (2018) (11)
Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies. (2016) (11)
Limited Reliability of the Spot Urine Protein/Creatinine Ratio in the Longitudinal Evaluation of Patients With Lupus Nephritis (2018) (11)
Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanism. (2011) (11)
183 A phase 1B/2A trial of tofacitinib, an oral janus kinase inhibitor, in systemic lupus erythematosus (2019) (10)
Antibodies and Brain Disease: A Convergence of Immunology and Physiology (2006) (10)
The preferential expression of the anti-DNA associated 8.12 idiotype in lupus is not genetically controlled. (1994) (10)
Buprenorphine Markedly Elevates a Panel of Surrogate Markers in a Murine Model of Sepsis (2019) (10)
In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to behavioral abnormalities resembling autism spectrum disorder in male mice (2020) (10)
Replacement of N-glycosylation sites on the MHC class II E alpha chain. Effect on thymic selection and peripheral T cell activation. (1995) (10)
Comparative study of idiotypes on monoclonal antibodies derived from patients with lupus and leprosy and from normal individuals. (1990) (10)
Than One Developmental Checkpoint High-Affinity DNA-Reactive B Cells at More-Estradiol Impairs Negative Selection of β 17 Hormonal Regulation of B Cell Development : Diamond (2006) (10)
Monoclonal anti-idiotypic antibodies to an I-J interacting molecule inhibit suppression in an H-2 restricted way. (1988) (10)
Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity (2021) (10)
Cognitive Dysfunction in SLE: a case for initiating trials. (2019) (9)
Overwhelming leukoencephalopathy as the only sign of neuropsychiatric lupus. (2005) (9)
Modulation of Fc-receptor expression and Fc-mediated phagocytosis in variants of a macrophage-like cell line. (1981) (9)
Accelerating Medicines Partnership: Organizational Structure and Preliminary Data From the Phase 1 Studies of Lupus Nephritis (2020) (9)
Use of anti-idiotypic antibodies to identify a receptor for the T-cell I-J determinant. (1985) (9)
CHAPTER 3 – General Features of Autoimmune Disease (2006) (8)
Activated basophils give lupus a booster shot (2010) (8)
A Second Heavy Chain Permits Survival of High Affinity Autoreactive B Cells (2004) (8)
Characterization of the human Ig VlII gene family and analysis of VlII and Cl polymorphism in systematic lupus erythematosus (1993) (8)
Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself. (1989) (8)
Erratum: Genetic control of autoimmune myocarditis mediated by myosin-specific antibodies (Immunogenetics (1999) 49 (79-85)) (1999) (8)
Microbial Antigens Can Elicit Autoantibody Production (1997) (8)
Quinolinic acid, a kynurenine/tryptophan pathway metabolite, associates with impaired cognitive test performance in systemic lupus erythematosus (2021) (8)
Analysis of V kI and VLDII Light Chain Genes in the Expressed B‐Cell Repertoire a (1995) (7)
Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis (2017) (7)
Response of a continuous macrophage-like cell line to MIF. (1979) (7)
Idiotypes in systemic lupus erythematosus. Clues for understanding etiology and pathogenicity. (1990) (7)
Erratum: Molecular characteristics of antibodies bearing an anti-DNA- associated idiotype (Journal of Experimental Medicine (December 1991) 174 (1639)) (1992) (6)
Requirements for suppressor cell activation. Role of accessory cells. (1989) (6)
The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches (2021) (6)
Systemic lupus erythematosus and Sjögren's syndrome. (2007) (6)
Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network (2021) (6)
Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype [published erratum appears in J Exp Med 1992 Jul 1;176(1):309] (1991) (6)
DNA antibodies focus on the light chain (1997) (6)
Monoclonal antibodies reactive with keratan sulfate-bearing tryptic fragments of bovine nasal cartilage proteoglycan. (1987) (5)
[Neuropsychiatric lupus and autoantibodies against ionotropic glutamate receptor (NMDAR)]. (2011) (5)
In utero exposure to maternal anti–aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring (2022) (5)
Molecular mapping of the 8.12 SLE-associated idiotype specificity at the single amino acid level. (1996) (5)
A structural investigation of FISLE-412, a peptidomimetic compound derived from saquinavir that targets lupus autoantibodies. (2017) (5)
Follicular dendritic cell dysfunction contributes to impaired antigen-specific humoral responses in sepsis-surviving mice. (2021) (5)
Mutations of Recombinant Aquaporin-4 Antibody in the Fc Domain Can Impair Complement-Dependent Cellular Cytotoxicity and Transplacental Transport (2018) (5)
Multiple encephalitogenic peptides of myelin basic protein in A.CA mice. (1993) (5)
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis (2021) (5)
Immune-mediated brain pathology: from autoantibodies to microglia. (2016) (5)
Analysis of the V kappa I family: germline genes from an SLE patient and expressed autoantibodies. (1995) (5)
The imperative to invest in science has never been greater. (2014) (4)
AI-19 T peripheral helper cells are expanded in the circulation of active SLE patients and correlate with CD21low B cells (2018) (4)
Systemic lupus erythematosus and Sjogren syndrome (2006) (4)
Chapter 28 – Pathogenesis of the Nervous System (2013) (4)
Cognitive Impairment in SLE: Mechanisms and Therapeutic Approaches (2021) (4)
Anti-DNA Antibodies: Structure, Regulation and Pathogenicity (2011) (4)
Use of anti-idiotypic antibodies to explore genetic mechanisms of production of anti-DNA antibodies. (1986) (4)
Chapter 8 – The Structure and Derivation of Antibodies and Autoantibodies (2013) (4)
Potentiation of Antiproliferative Effects of Monoclonal Antibody Lym‐1 and Immunoconjugate Lym‐1‐gelonin on Human Burkitt's Lymphoma Cells with γ‐Interferon and Tumor Necrosis Factor (1995) (4)
Generation of functional I-Ed variants from an antigen-presenting macrophage cell line. (1985) (4)
Speculation on the Role of Somatic Mutation in the Generation of Anti‐DNA Antibodies a (1986) (4)
Chapter 13 – B Cells (2017) (3)
In vivo detection of deposition of radiolabeled lupus antikidney antibody and its inhibition by soluble antigen. (2001) (3)
Autoimmune demyelination in transgenic E alpha d-positive A.CA mice. Comparison with E-negative A.CA mice. (1992) (3)
Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies (2022) (3)
Using the Mouse to Model Human Diseases: Cognitive Impairment in Systemic Lupus Erythematosus (2020) (3)
Genetic recombination in the α2 domain of the Eα chain yields an Ed molecule with altered T cell activation (1990) (3)
B Cells and Generation of Antibodies (2019) (3)
Selective regulation of autoreactive B cells by Fc γ RIIB (2009) (3)
B cells twist and shout (2009) (3)
Human recombinant Fab fragments with sub-nanomolar affinities for acetylated histones. (2008) (3)
Analysis of V kappa I and V lambda II light chain genes in the expressed B-cell repertoire. (1995) (3)
A double-blind, placebo-controlled, phase II, randomized study of lovastatin therapy in the treatment of mildly active rheumatoid arthritis. (2020) (3)
Pathogenesis of SLE: implications for rational therapy (2004) (3)
Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis (2019) (3)
Genetic and Functional Studies of Continuous Macrophage-Like Cell Lines (1980) (3)
Anti-DNA antibodies (2021) (3)
Using peptide mimetopes to elucidate anti-polysaccharide and anti-nucleic acid humoral responses. (2003) (3)
Effect of vitamin D on serum markers of bone turnover in SLE in a randomised controlled trial (2019) (3)
Idiotypes in Systemic Lupus Erythematosus (1990) (2)
204 The immune cell landscape in kidneys of lupus nephritis patients (2019) (2)
Endothelial Cells and Inflammation (2014) (2)
Monoclonal antibodies. (1982) (2)
Editorial: The Role of HMGB1 in Immunity (2020) (2)
51 – Systemic lupus erythematosus (2008) (2)
IL-17–producing follicular Th cells enhance plasma cell differentiation in lupus-prone mice (2022) (2)
10 – ANTI-DNA ANTIBODIES: Structure, Assembly, and Diversity (2004) (2)
Effect of somatic mutation on antibody affinity and specificity. (1986) (2)
Anti-DNA antibodiesStructure, Assembly, and Diversity (2004) (2)
Variable region gene utilization and environmental antigens in autoimmunity. (1988) (2)
Monoclonal antibodies. A new technique for producing serologic reagents. (1981) (2)
OP0002 Multicriteria decision analysis for developing new classification criteria for systemic lupus erythematosus (2017) (2)
Idiotypic analyses of anti-DNA antibodies in systemic lupus and monoclonal gammopathy. (1988) (2)
CD1c-reactive, Th2 cytokine producing T-cells in human autoimmune disease (1998) (2)
Anti-idiotypes and autoimmunity (1993) (2)
Response to “HMGB1 Mediates Cognitive Impairment in Sepsis Survivors” (2012) (2)
Idiotypes in Systemic Lupus Erythematosus (Part 1 of 2) (1990) (2)
Somatic mutation alters affinity and specificity. (1985) (2)
B cell hyporesponsiveness and autoimmunity: a new paradigm. (2007) (2)
Studies on the role of somatic mutation in the generation anti-DNA antibodies. (1987) (2)
Systemic Lupus Erythematosus T Cell Studies in a Peptide-Induced Model of and Betty Diamond (2001) (2)
The Role of NG2 Glial Cells in ALS Pathogenesis (2013) (1)
Mechanisms of Endothelial Activation (2014) (1)
Lupus auto-antibodies act as positive allosteric modulators at NMDA receptors and induce spatial memory deficits (2019) (1)
Systemic Lupus Erythematosus (2019) (1)
Integration of urine proteomics and renal single-cell genomics identifies an interferon-gamma response gradient in lupus nephritis. (2020) (1)
FRI0283 Dynamic contrast enhanced mri (DCE-MRI) demonstrates hippocampus permeability in sle (2018) (1)
Radiolabeled Exosomes for the Early Detection of Metastases and to Predict Breast Cancer Premetastatic Niche (2014) (1)
Fundamental role of C1q in autoimmunity and inflammation (2015) (1)
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership. (2022) (1)
Microbial antigens can elicit autoantibody production. A potential pathway to autoimmune disease. (1997) (1)
Cyanogen Bromide Fragments of Mouse IgG2a and IgG2b which Bind to their Fc Receptors on Mouse Macrophages (1982) (1)
Autoimmunity (2005) (1)
Alteration of the T-cell receptor repertoire in A. CA mice expressing anEad transgene (2005) (1)
The Anti-DNA Response in Lupus (1999) (1)
Generation and regulation of B cell autoreactivity arising in the periphery. (1996) (1)
Introduction to immunology at Feinstein Institute for Medical Research (FIMR) (2015) (1)
Award Number: W81XWH-11-1-0491 TITLE: Role of MicroRNA in Aggressive Prostate Cancer PRINCIPAL INVESTIGATOR: Hsieh, Jer-Tsong CONTRACTING ORGANIZATION: University of Texas, Southwestern Medical Center at Dallas (2014) (1)
Systemic lupus erythematosus and Sjögren's syndrome. (2007) (1)
50 – Systemic lupus erythematosus (2013) (1)
CT-03 Phase 2 trial of induction therapy with anti-CD20 (rituximab) followed by maintenance therapy with anti-BAFF (belimumab) in patients with active lupus nephritis (2018) (1)
HMGB1 mediating C1Q adhesion on dendritic synapses of cultured cortical neurons through activated NMDA receptor (2017) (1)
178 Phase 2 trial of induction therapy with anti-CD20 (Rituximab) followed by maintenance therapy with anti-BAFF (Belimumab) in patients with active lupus nephritis (2019) (1)
FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation (2021) (1)
SAT0189 Comparative analysis of alternative outcome measures for use in lupus nephritis trials (2013) (1)
7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) (2009) (1)
1702 Patients enrolled in the accelerating medicines partnership (AMP) RA/SLE network with isolated renal disease report minimal quality of life impairment on PROMIS-29 compared to patients with extrarenal symptoms (2022) (1)
C D 5 and Immunoglobulin V Gene Expression in B-Cell Lymphomas and Chronic Lymphocytic Leukemia (2003) (1)
B cell tolerance, autoimmunity and autoimmune disease (2005) (1)
THU0271 PERFORMANCE OF THE EULAR/ACR 2019 CLASSIFICATION CRITERIA FOR SYSTEMIC LUPUS ERYTHEMATOSUS IN EARLY DISEASE, ACROSS SEXES AND ETHNICITIES (2020) (1)
Georgia Abortion Law and Our Commitment to Patients (2020) (1)
Inhibition of Human Erythropoiesis during Inflammation Is Mediated By High Mobility Group Box Protein 1 (HMGB1) through Decreased Commitment of Hematopoietic Stem Cells to the Erythroid Lineage and By Increased Apoptosis of Terminally Differentiating Erythroblasts (2016) (1)
SARS-CoV-2 and interferon blockade (2020) (0)
Award Number: W81XWH-11-1-0491 TITLE: Role of microRNA in aggressive prostate cancer PRINCIPAL INVESTIGATOR: Hsieh, Jer-Tsong CONTRACTING ORGANIZATION: UT Southwestern Medical Center (2013) (0)
Contribution of BAFF and DNA‐containing Immune Complexes to the Generation of DNA‐reactive B cells (2008) (0)
Award Number: W81XWH-11-1-0775 TITLE: Investigating the Regulation and Potential Role of Nonhypoxic Hypoxia- Inducible Factor 1 (HIF-1) in Aromatase Inhibitor Resistant Breast Cancer (2012) (0)
Award Number: W81XWH-11-1-0637 TITLE: “The Role of Gluococorticoids and Neuroinflammation in Mediating the Effects of Stress on Drug Abuse” PRINCIPAL INVESTIGATOR: (2015) (0)
Dysfunctional expansion of immature granulocytes in sepsis survivors. (2016) (0)
HMGB1 Causes Anemia of Inflammation By Modulating Erythropoietin Signal Transduction (2018) (0)
Rheumatoid arthritis and other inflammatory joint diseases (human studies) (PP-036) (2010) (0)
AB0167 SINGLE CELL RNA EXPRESSION IN LUPUS NEPHRITIS COMPARING AFRICAN-AMERICAN AND CAUCASIAN PATIENTS IDENTIFIES DIFFERENTIAL EXPRESSION OF TYPE I INTERFERON PATHWAY (2019) (0)
Molecular Analysis of the Human Immunoglobulin VAII Gene Family (2013) (0)
Targeting DEC-205−DCIR2+ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis (2018) (0)
HEMATOPOIESIS AND STEM CELLS The function of hematopoietic stem cells is altered by both genetic and in ﬂ ammatory factors in lupus mice (2013) (0)
Award Number: W81XWH-12-1-0284 TITLE: Development of Targeted Nanobubbles for Ultrasound Imaging and Ablation of Metastatic Prostate Cancer Lesions (2014) (0)
AI-02 Dissecting immune phenotypes in SLE (2018) (0)
TITLE: Reciprocal Interactions between Multiple Myeloma Cells and Osteoprogenitor Cells Affect Bone Formation and Tumor Growth” (2015) (0)
Cells in a Model of Estrogen-Induced Lupus Population of Autoreactive Marginal Zone B Cutting Edge: Expansion and Activation of A (2013) (0)
Award Number: W81XWH-11-1-0567 TITLE: GLOBAL EPIGENETIC CHANGES MAY UNDERLIE ETHNIC DIFFERENCES AND SUSCEPTIBILTY TO PROSTATE CANCER PRINCIPAL INVESTIGATOR: BERNARD KWABI-ADDO PhD CONTRACTING ORGANIZATION: HOWARD (2013) (0)
An E alpha E beta heterodimer dramatically alters selection of functional T-cell subsets in A.CA transgenic mice. (1993) (0)
AWARD NUMBER: W81XWH-14-1-0369 TITLE: Maternal Brain-Reactive Antibodies and Autism Spectrum Disorder PRINCIPAL INVESTIGATOR: Betty Diamond CONTRACTING ORGANIZATION: Feinstein Institute for Medical Research (2016) (0)
Hypoxia-inducible factor 1α is a negative regulator of IRF5 in hypoxic macrophages (2021) (0)
Erythematosus Interactor-Ig in Murine Systemic Lupus Activator and Calcium Modulator Ligand Mechanism of Action of Transmembrane Diamond (2004) (0)
Award Number: W81XWH-11-1-0409 TITLE: Portable Low-Volume Therapy for Severe Blood Loss PRINCIPAL INVESTIGATOR: Matthew T. Andrews CONTRACTING ORGANIZATION: University of Minnesota (2015) (0)
Maternal Brain-Reactive Antibodies and Autism Spectrum Disorder (2015) (0)
Award Number: W81XWH-12-2-0067 TITLE: The Potential Application and Risks Associated With the Use of Predatory Bacteria as a Bio-control Agent Against Wound Infections (2015) (0)
Cancer and Neuropathies (2014) (0)
Award Number: W81XWH-12-1-0327 TITLE: Transgastric Local Pancreatic Hypothermia: A Novel, Rapid Multimodal Therapy for Acute Pancreatitis (2016) (0)
Visualizing Breast Cancer Cell Interaction With Tumor-Infiltrating Lymphocytes During Immunotherapy (2013) (0)
alpha7 nicotinic acetylcholine receptor and cAMP response element binding protein are essential for prolonged monocyte deactivation by vagus nerve signaling (116.37) (2011) (0)
Genetic recombination in the alpha 2 domain of the E alpha chain yields an Ed molecule with altered T cell activation. (1990) (0)
SARS-CoV-2 and interferon blockade (2020) (0)
Award Number: W81XWH-12-1-0605 TITLE: Molecular Indicators of Castration-Resistant Prostate Cancer PRINCIPAL INVESTIGATOR: (2015) (0)
F.99. Identification of Signaling Alterations in Rheumatoid Arthritis by Phospho-specific Flow Cytometry (2009) (0)
1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortium (2022) (0)
The Genotype and Phenotype (GAP) Registry: A National Resource for Studying Genetic Regulation of Immune Function in Normal Populations (2010) (0)
Award Number: W81XWH-12-1-0346 TITLE: Targeting PRMT5 as a Novel Radiosensitization Approach for Primary and Recurrent Prostate Cancer Treatment (2014) (0)
Award Number: W81XWH-12-1-0172 TITLE: Effect of Physical Forces on the Metastatic Bone Microenvironment PRINCIPAL INVESTIGATOR: (2014) (0)
Galantamine attenuates autoinflammation in a mouse model of familial mediterranean fever (2022) (0)
Award Number: W81XWH-10-1-0713 TITLE: Magnetic Resonance Characterization of Axonal Response to Spinal Cord Injury (2013) (0)
1509 Differences in chromatin architecture pre- and post-induction therapy in pediatric lupus patients (2021) (0)
Award Number: W81XWH-13-1-0129 TITLE: MAXIMIZING PTH ANABOLIC OSTEOPOROSIS THERAPY PRINCIPAL INVESTIGATOR: JOSEPH BIDWELL CONTRACTING ORGANIZATION: TRUSTEES OF INDIANA (2018) (0)
Award Number: W81XWH-12-1-0062 TITLE: Molecular Determinants of Hormone-Refractory Prostate Cancer (2015) (0)
Autoantibodies and cognitive impairment in systemic lupus erythematosus (2004) (0)
Gene-antigen register An EctE heterodimer dramatically alters selection of functional T-cell subsets in A . CA transgenic mice (0)
Reduced expression of inflammation regulatory proteins, ETS‐1 and TNIP‐1, may cause lupus in humans (2019) (0)
Nerve Degeneration and Regeneration Associated with NF1 Tumors (2014) (0)
9.5-01 Characterization of a murine homolog of Y box binding protein (1989) (0)
Autoimmune Myocarditis and Pericarditis (2014) (0)
Protein Aggregation Inhibitors for ALS Therapy (2013) (0)
An idiotype systems update. (1992) (0)
A murine macrophage line of the H-2 d / f haplotype can activate H-2 k suppressor T cells ( antigen-presenting cell / suppression / glycosylation ) (0)
A murine macrophage line of the H-2d/f haplotype can activate H-2k suppressor T cells (1990) (0)
1112 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritisbetter than proteinuria (2022) (0)
Maternal antibodies and fetal brain development (2010) (0)
Combating Drug Abuse by Targeting Toll-Like Receptor 4 (TLR4) (2014) (0)
Developing a Mouse Model of Sensory and Cognitive Deficits for Multiple Sclerosis (2012) (0)
Erratum: Position statement, association of American physicians the imperative to invest in science has never been greater (Journal of Clinical Investigation (2014) 124:11 (5085) DOI:10.1172/JCI79469) (2014) (0)
An EαEβ heterodimer dramatically alters selection of functional T-cell subsets in A.CA transgenic mice (2004) (0)
AWARD NUMBER: W81XWH-12-1-0345 PROJECT TITLE: Combating drug abuse by targeting toll-like receptor 4 (TLR) PRINCIPAL INVESTIGATOR: Dr. Linda Watkins CONTRACTING ORGANIZATION: University of Colorado, Boulder (2016) (0)
16 – Systemic Lupus Erythematosus: Descriptive Past and Mechanistic Future (2007) (0)
A Systems Immunology Approach Identifies Cytokine-Induced STAT Signaling Pathways Critical to Rheumatoid Arthritis Disease Activity and Treatment Response (2019) (0)
TITLE: Understanding and Targeting Epigenetic Alterations in Acquired Bone Marrow Failure (2013) (0)
Myeloid cytokines distinctly and reversibly control LAIR-1 (CD305) expression on monocytes-mΦs/monocyte-DCs. (2016) (0)
Award Number: W81XWH-13-1-0106 TITLE: Functional Characterization of CENP-A Post-Translational Modifications in Chromosome Segregation PRINCIPAL INVESTIGATOR: Sathyan (2015) (0)
TITLE: Exploring the Interaction between TSC2, PTEN, and the NMDA Receptor in Animal Models of Tuberous Sclerosis (2014) (0)
IgM anti-DNA antibody and C1q Immune complexes regulate the production of Interferon-{alpha} in plasmacytoid dendritic cells (2012) (0)
Reply: (2019) (0)
A monoclonal antibody from a mother of a child with autism resulted in cortical and behavioral alterations in male but not in female mice (2014) (0)
Mimicry between DNA, Carbohydrates, and Peptides: Implications in Systemic Lupus Erythematosus (2000) (0)
Translating and Communicating Immunology (2010) (0)
Award Number: W81XWH-13-1-0129 TITLE: Maximizing PTH Anabolic Osteoporosis Therapy PRINCIPAL INVESTIGATOR: JOSEPH BIDWELL CONTRACTING ORGANIZATION: TRUSTEES OF INDIANA UNIVERSITY (2016) (0)
SLE risk alleles and cell development and activation (2012) (0)
Monoclone antibodies and their use (1983) (0)
Monoclone antibodies and their use (1983) (0)
Idiotypes in Systemic Lupus Erythematosus (Part 2 of 2) (1990) (0)
Antinuclear antibodies: Contemporary techniques and clinical application to connective tissue diseases by Gale A. McCarty, Donald W Valencia and Marvin, J Fritzler, Oxford University Press, 1984. £25. 00 (viii + 95 pages) ISBN 0 195 03433 3. (1985) (0)
Determination of the Role of Estrogen Receptors and Estrogen Regulated Genes in B Cell Autoreactivity (2008) (0)
Expansion of the IgD class switched B cell population in carriers of the autoimmune disease associated risk haplotype in BLK (HUM2P.332) (2014) (0)
DAB 2 IP IB : Skp 2 P : Skp 2 In MG 132 (2014) (0)
Sex Hormones and B Cells (2004) (0)
Anti-DNA producing B cells from mice transgenic for a gamma-2b anti-DNA heavy chain express Vk1 light chains and are not allelically excluded (1993) (0)
Contributions of Sex Chromosomes and Gonadal Hormones to the Male Bias in a Maternal Antibody-Induced Model of Autism Spectrum Disorder (2021) (0)
Reply: (2019) (0)
C1q engages leukocyte-associated inhibitory receptor (LAIR)-1 and inhibits monocyte-derived dendritic cell differentiation (167.1) (2012) (0)
LPP is Required for TGF-Beta Induced Motility and Invasion of Neu/ErbB-2 Expressing Breast Cancer Cells (2012) (0)
Mechanisms of anti-NMDAR Antibody Mediated Damage to the Fetal Brain (2020) (0)
In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to an autism-like phenotype in male mice (2020) (0)
GENETIC IMPACT ON CHROMATIN ACCESSIBILITY IN SLE (2021) (0)
B-Cell Mediated Humoral Responses Are Impaired in Sepsis Survivors (2018) (0)
Blimp-1 and systemic lupus erythematosus (2014) (0)
Award Number: W81XWH-11-1-0350 TITLE: The CXCR/EGFR Axis in the Initiation and Progression of Prostate Cancer PRINCIPAL INVESTIGATOR: Gwyneth Halstead Nussloch CONTRACTING ORGANIZATION: Regents of the University of Michigan (2012) (0)
Epidermal growth factor receptor (EGFR) family members are dysregulated in a number of epithelial cell malignancies, including breast cancer[1]. The first three members of the family: EGFR/HER1, HER2 and HER3 promote oncogenic transformation, more proliferative and aggressive (2012) (0)
Award Number: W81XWH-11-1-0692 TITLE: Targeting Prostate Cancer with Bifunctional Modulators of the Androgen Receptor PRINCIPAL INVESTIGATOR: Anna Mapp CONTRACTING ORGANIZATION: REGENTS OF THE UNIVERSITY OF MICHIGAN (2015) (0)
Choline acetyltransferase+ lymphocytes regulate endothelial nitric oxide synthase (MUC2P.939) (2015) (0)
Reproductive issues in rheumatology: do you know how to advise your patients?I1. Is pregnancy a stress test for subsequent development of autoimmunity? (2012) (0)
Uterine-Specific Knockout of Tsc-2: A Mouse Model for Lymphangioleiomyomatosis (2013) (0)
Award Number: W81XWH-12-1-0313 TITLE: Divergent Effects of Dendritic Cells on Pancreatitis PRINCIPAL INVESTIGATOR: Dr. George Miller CONTRACTING ORGANIZATION: New York University (2015) (0)
Award Number: W81XWH-11-1-0499 TITLE: Deciphering the Translational Determinants of Prostate Cancer Initiation and Progression PRINCIPAL INVESTIGATOR: Andrew C. Hsieh CONTRACTING ORGANIZATION: Unversity of California, San Francisco (2012) (0)
Investigating the Mechanism of Mena(INV)-Driven Metastasis (2013) (0)
The indigenous gut microbiota modulates the blood–brain barrier in mice (2012) (0)
Title: Excessive Cap-dependent Translation as a Molecular Mechanism Underlying Asd Excessive Cap-dependent Translation as a Molecular Mechanism of Asd 5f. Work Unit Number 7. Performing Organization Name(s) and Address(es) and Address(es) 8. Performing Organization Report Number Approved for Public (2012) (0)
AQP4-IgG placental transfer in NMO pregnancies (2014) (0)
0402 TITLE : Mammary Cancer and Activation of Transposable Elements ! (2015) (0)
TD-05 Dynamic contrast enhanced MRI (DCE-MRI) demonstrates hippocampus permeability in SLE (2018) (0)
UTILITY IN CLINICAL PRACTICE OF IGA ANTI-TISSUE TRANSGLUTAMINASE ANTIBODY FOR THE DIAGNOSIS OF CELIAC DISEASE (2005) (0)
Cyclin-dependent kinase inhibitor VMY-1-103 induces a G2/M cell cycle arrest and apoptosis in prostate cancer (2012) (0)
205 Single cell RNA expression in lupus nephritis comparing african-american and caucasian patients identifies differential expression of type I interferon pathway (2019) (0)
Lupus Erythematosus Provide Help for IgG Human Double-Negative T Cells in Systemic (2000) (0)
C1q-based tolerance mechanism in HMGB1-mediated activation of human monocytes (IRM5P.649) (2015) (0)
Award Number: W81XWH-13-1-0151 TITLE: Nano-siRNA Particles and Combination Therapies for Ovarian Tumor Targeting PRINCIPAL INVESTIGATOR: (2015) (0)
Chemical Strategy to Translate Genetic/Epigenetic Mechanisms to Breast Cancer Therapeutics (2012) (0)
264 Pearl: pathway exploration and analysis in renal disease in the accelerating medicine partnership (amp) lupus network (2017) (0)
Autoimmune mechanisms (SY2-2) Chairpersons: Shigekazu Nagata, Betty Diamond (2010) (0)
FRI0397 Relationship between Igg Anti-Nr2 Glutamate Receptor Antibodies and Depressive/Anxiety Symptoms in Patients with Systemic Lupus Erythematosus (2014) (0)
Award Number: W81XWH-10-1-0773 TITLE: Mechanical Loading for Peripheral Nerve Stabilization and Regeneration PRINCIPAL INVESTIGATOR: (2012) (0)
Yap1 as a New Therapeutic Target in Neurofibromatosis Type 2 (2013) (0)
Award Number: W81XWH-12-2-0038 TITLE: Prevention of Blast-Related Injuries PRINCIPAL INVESTIGATOR: Albert I. King CONTRACTING ORGANIZATION: Wayne State University (2013) (0)
Response in Peptide-Induced Autoimmunity Molecular Analysis of the Autoantibody (2000) (0)
B Cells Producing Pathogenic Autoantibodies (2015) (0)
Award Number: W81XWH-14-1-0007 TITLE: Competitive Endogenous RNAs in Prostate Cancer (2015) (0)
Performance of the EULAR/ACR 2019 Classifi cation Criteria for Systemic Lupus Erythematosus in Men, Diverse Ethnicities, and Early Disease (2019) (0)
B lymphocytes in Treatment-Naïve Pediatric Lupus Patients are Epigenetically Distinct from Healthy Children (2022) (0)
Development of Non-Hormonal Steroids for the Treatment of Duchenne Muscular Dystrophy (2013) (0)
Obesity Exposure Across the Lifespan on Ovarian Cancer Pathogenesis (2014) (0)
O8 Performance of the EULAR/ACR 2019 classification criteria for systemic lupus erythematosus in men, ethnicities, and early disease (2020) (0)
Award Number: W81XWH-10-0539 TITLE: Pre-Clinical Testing of New Hydroxybutyrate Analogues PRINCIPAL INVESTIGATOR: (2013) (0)
AWARD NUMBER: W81XWH-12-1-0213 TITLE: Targeting G-Protein Signaling for the Therapeutics of Prostate Tumor Bone Metastases and the Associated Chronic Bone Pain (2014) (0)
0666 TITLE : BMP 7 Induces Dormancy of Prostatic Tumor Stem Cell in Bone PRINCIPAL INVESTIGATOR : (2013) (0)
The brain in SLE (2021) (0)
IgM anti-DNA antibody and C1q Immune complexes regulate the production of Interferon-α in plasmacytoid dendritic cells (159.26) (2012) (0)
Maternal antibodies and developing blood–brain barrier (2015) (0)
Maturation but Not Survival Tamoxifen Blocks Estrogen-Induced B Cell (2013) (0)
Endogenous Control of Dendritic Cell Activation by miRNA (2015) (0)
TITLE : Systems-Level Analysis of EGFR Inhibition-DNA Damage Combination Treatment in Breast Cancer (2012) (0)
TITLE: Zebrafish Model of NF1 for Structure-Function Analysis, Mechanisms of Glial Tumorigenesis, and Chemical Biology (2013) (0)
301 The Lupus Risk Index (LRI) as a biomarker in patients with lupus nephritis (2022) (0)
Award Number: W81XWH-12-1-0179 TITLE: Unbiased Combinatorial Genomic Approaches to Identify Alternative Therapeutic Targets within the TSC Signaling Network PRINCIPAL INVESTIGATOR: Norbert Perrimon CONTRACTING ORGANIZATION: Harvard College, President and Fellows of Sponsored Programs (2014) (0)
SLE and other connective tissue diseases (animal models) (PP-017) (2010) (0)
SLE and other connective tissue diseases (animal models) (WS-017) Chairpersons: Takayuki Sumida, Sachiko Hirose (2010) (0)
Choline Acetyltransferase-Expressing T cells are rare in young mice (122.7) (2012) (0)
Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus ( hybridoma / epitope / network theory / autoantibody / anti-idiotypic antibody ) (0)
Autoantibodies to Endothelial Cells (2014) (0)
Award Number: W81XWH-12-1-0506 TITLE: Novel Therapeutic Targets to Treat Social Behavior Deficits in Autism and Related Disorders (2013) (0)
A Forward Genetic Screening for Prostate Cancer Progression Genes (2012) (0)
and Betty pneumoniae Streptococcus Dominant Epitope Found on Peptide Mimic of Phosphorylcholine , a (2000) (0)
Letter from Incoming Editor in Chief of Molecular Medicine, Dr. Betty Diamond (2014) (0)
Systemic Lupus Erythematosus T Cell Studies in a Peptide-Induced Model of (2017) (0)
TITLE: Role and Mechanism of Structural Variation in Progression of Breast Cancer (2013) (0)
Pro‐inflammatory immune complexes are sufficient to induce a lupus‐like phenotype in R4AxFcRIIb−/− BALB/c mice (2008) (0)
Award Number: W81XWH-12-1-0606 TITLE: Stem Cell-Based Therapies for Epidermolysis Bullosa (2015) (0)
Association of CSK Variants with Systemic Lupus Erythematosus (2010) (0)
TITLE: Examination of the mGluR-mTOR Pathway for the Identification of Potential Therapeutic Targets to Treat Fragile X. PRINCIPAL INVESTIGATOR: (2013) (0)
A crucial role of IL-6 in B cell tolerance induction after antigen activation (167.6) (2011) (0)
Award Number: W81XWH-12-1-0401 TITLE: Development of Novel Drugs That Target Coactivation Sites of the Androgen Receptor for Treatment of Antiandrogen-Resistant Prostate Cancer (2014) (0)
9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) (2014) (0)
Award Number: W81XWH-09-1-0737 TITLE: Optimizing Screening and Risk Assessment for Suicide Risk in the U.S. Military PRINCIPAL INVESTIGATOR: (2014) (0)
Correction to: Cognitive Impairment in SLE: Mechanisms and Therapeutic Approaches (2021) (0)
Increased mitochondrial metabolism profile is required for immunologic function in age associated B cells (2022) (0)
Lupus anti-DNA antibodies bearing the 8.12 idiotype appear to be somatically mutated (2004) (0)
Role of Environmental Antigen in Triggering anti-DNA Antibody Production (1997) (0)
Vagal tonic activity modulates immune suppression in sepsis survivors (2018) (0)
CT-02 Features of patients screened for calibrate (rituximab plus cyclophosphamide followed by belimumab for the treatment of lupus nephritis); hypogammaglobulinemia is frequent in patients with marked elevation of urinary protein (2016) (0)
2002 Distinct intrarenal monocyte and macrophage populations differentiate into a common phagocytic state that is associated with histopathologic kidney injury in human lupus nephritis (2022) (0)
Alteration in TNFα mediates impaired antigen-specific humoral responses in sepsis survivors (2020) (0)
Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory (2020) (0)
Cognitive dysfunction in SLE: An understudied clinical manifestation. (2022) (0)
SAT0173 Molecular signatures in SLE: untangling flare from infection (2013) (0)
Ultrasound neuromodulation of an anti-inflammatory pathway at the spleen produces sustained improvement of experimental pulmonary hypertension (2023) (0)
101 Increased blood brain barrier permeability associates with increased hippocampal glucose metabolism in SLE (2021) (0)
Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling (2023) (0)
Acknowledgment to reviewers (2018) (0)
Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus (2018) (0)
Associations between circulating interferon and kynurenine/tryptophan pathway metabolites: support for a novel potential mechanism for cognitive dysfunction in SLE (2022) (0)
272 Clinical significance of anti-dna/nr2 antibodies in de novo npsle and post-steroid npsle (2017) (0)
The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits (2015) (0)
Thiocarbazate building blocks enable the construction of azapeptides for rapid development of therapeutic candidates (2022) (0)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (0)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (0)
HMGB1‐mediated microglial activation as a mechanism for cognitive dysfunction in neuropsychiatric lupus (2022) (0)
621 The Association of Interferon with Kynurenine/Tryptophan Pathway Activation in Systemic Lupus Erythematosus (2022) (0)
Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression (2017) (0)

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