Betül Kırdar
#126,925
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Turkish molecular and systems biologist
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Betül Kırdarbiology Degrees
Biology
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#16159
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Systems Biology
#40
World Rank
#40
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Molecular Biology
#2812
World Rank
#2857
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Biology
Why Is Betül Kırdar Influential?
(Suggest an Edit or Addition)According to Wikipedia, Betül Kırdar is a Turkish molecular and systems biologist researching design strategies of microorganisms, metabolic engineering, and biological networks. She is a professor in the department of chemical engineering at Boğaziçi University.
Betül Kırdar's Published Works
Published Works
- Integration of metabolome data with metabolic networks reveals reporter reactions (2006) (151)
- Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe (2000) (129)
- Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. (2010) (116)
- Effect of wastewater composition on archaeal population diversity. (2005) (93)
- Mathematical description of ethanol fermentation by immobilised Saccharomyces cerevisiae (1998) (88)
- Doxorubicin induces an extensive transcriptional and metabolic rewiring in yeast cells (2018) (87)
- Ethanol production and fermentation characteristics of recombinant saccharomyces cerevisiae strains grown on starch (1998) (75)
- Evaluation of industrial Saccharomyces cerevisiae strains for ethanol production from biomass (2012) (72)
- Metabolic pathway analysis of yeast strengthens the bridge between transcriptomics and metabolic networks (2004) (68)
- Evaluation of performance, acetoclastic methanogenic activity and archaeal composition of full-scale UASB reactors treating alcohol distillery wastewaters (2006) (62)
- Genome-Wide Transcriptional Response of Saccharomyces cerevisiae to Stress-Induced Perturbations (2016) (57)
- Biomass composition: the “elephant in the room” of metabolic modelling (2015) (57)
- Improvement of ethanol production from starch by recombinant yeast through manipulation of environmental factors (2002) (54)
- Analysis of the CFTR gene in Turkish cystic fibrosis patients: identification of three novel mutations (3172delAC, P1013L and M1028I) (1998) (52)
- A Novel Strategy for Selection and Validation of Reference Genes in Dynamic Multidimensional Experimental Design in Yeast (2012) (50)
- Production of Ethanol from Starch by Respiration-Deficient Recombinant Saccharomyces cerevisiae (2005) (49)
- How yeast re-programmes its transcriptional profile in response to different nutrient impulses (2011) (47)
- Effect of carbon source perturbations on transcriptional regulation of metabolic fluxes in Saccharomyces cerevisiae (2007) (46)
- Bioconversion of starch into ethanol by a recombinant Saccharomyces cerevisiae strain YPG-AB (2002) (40)
- Purification, biochemical characterization and gene sequencing of a thermostable raw starch digesting α-amylase from Geobacillus thermoleovorans subsp. stromboliensis subsp. nov. (2011) (40)
- Optimization of medium composition for biomass production of recombinant Escherichia coli cells using response surface methodology (2006) (38)
- Integrative investigation of metabolic and transcriptomic data (2006) (37)
- Flux Balance Analysis of a Genome‐Scale Yeast Model Constrained by Exometabolomic Data Allows Metabolic System Identification of Genetically Different Strains (2007) (36)
- Study of 15 protein polymorphisms in a sample of the Turkish population. (1998) (35)
- Understanding signaling in yeast: Insights from network analysis (2007) (33)
- Optimizing medium composition for TaqI endonuclease production by recombinant Escherichia coli cells using response surface methodology (2005) (32)
- A Novel 13 BP Deletion in the 3′UTR of the β-Globin Gene Causes β-Thalassemia in a Turkish Patient (1993) (28)
- Sequence variations within the genes related to hemostatic imbalance and their impact on coronary artery disease in Turkish population. (2007) (25)
- Integration of Metabolic Modeling and Phenotypic Data in Evaluation and Improvement of Ethanol Production Using Respiration-Deficient Mutants of Saccharomyces cerevisiae (2008) (24)
- The molecular basis of β-thalassemia in Turkey (1992) (22)
- Transcriptional remodelling in response to changing copper levels in the Wilson and Menkes disease model of Saccharomyces cerevisiae. (2013) (22)
- An integrative analysis of transcriptomic response of ethanol tolerant strains to ethanol in Saccharomyces cerevisiae. (2016) (22)
- Cystic Fibrosis Mutation and Associated Haplotypes in Turkish Cystic Fibrosis Patients (2001) (20)
- Cybernetic modelling of growth and ethanol production in a recombinant Saccharomyces cerevisiae strain secreting a bifunctional fusion protein (2002) (20)
- Screening of deletions and RFLP analysis in Turkish DMD/BMD families by PCR (1993) (19)
- A system based network approach to ethanol tolerance in Saccharomyces cerevisiae (2014) (18)
- Use of Agro Waste Biomass for α-Amylase Production by Anoxybacillus amylolyticus: Purification and Properties (2014) (18)
- A novel deletion in a Turkish beta-thalassemia patient detected by DGGE and direct sequencing: FSC 22-24 (-7 bp). (1993) (17)
- Identification of the parental origin of polysomy in two 49,XXXXY cases (1997) (17)
- Real imaging and size values of Saccharomyces cerevisiae cells with comparable contrast tuning to two environmental scanning electron microscopy modes. (2007) (16)
- Screening of Deletions in SMN, NAIP and BTF2p44 Genes in Turkish Spinal Muscular Atrophy Patients (2000) (16)
- A novel frameshift mutation : deletion of C in codons 74-75 of the β-globin gene causes β°-Thalassemia in a Turkish patient (1992) (14)
- Annotation of unknown yeast ORFs by correlation analysis of microarray data and extensive literature searches (2006) (14)
- Plasmid stability in a recombinant S cerevisiae strain secreting a bifunctional fusion protein (2001) (14)
- A novel integrative network approach to understand the interplay between cardiovascular disease and other complex disorders. (2011) (14)
- Transcriptomic response of yeast cells to ATX1 deletion under different copper levels (2016) (12)
- Optimal substrate feeding policy for fed-batch cultures of S. cerevisiae expressing bifunctional fusion protein displaying amylolytic activities (2003) (12)
- Simultaneous modeling of enzyme production and biomass growth in recombinant Escherichia coli using artificial neural networks (2008) (11)
- Polymorphisms associated with the FVIII and FIX genes in the Turkish population (1995) (11)
- High-level production of TaqI restriction endonuclease by three different expression systems in Escherichia coli cells using the T7 phage promoter (2002) (11)
- Yeast cells with impaired drug resistance accumulate glycerol and glucose. (2014) (11)
- High level secretion of TaqI restriction endonuclease by recombinant Escherichia coli (1999) (11)
- A novel topological centrality measure capturing biologically important proteins. (2016) (10)
- Recovery of antithrombin III from milk by expanded bed chromatography. (2002) (10)
- Saccharomyces cerevisiae adapted to grow in the presence of low-dose rapamycin exhibit altered amino acid metabolism (2018) (10)
- A simple structured model for biomass and extracellular enzyme production with recombinant Saccharomyces cerevisiae YPB-G (2002) (10)
- Complex Disease Interventions from a Network Model for Type 2 Diabetes (2013) (9)
- Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment. (2012) (9)
- Identification of point mutations in Turkish DMD/BMD families using multiplex-single stranded conformation analysis (SSCA) (1999) (9)
- Prenatal prediction of childhood‐onset spinal muscular atrophy (SMA) in Turkish families (2002) (9)
- A structured model for intracellular EcoRI endonuclease production by recombinant E. coli 294 (2001) (7)
- Expression of a thermostable restriction endonuclease in recombinant Escherichia coli cells and optimization of fermentation conditions (2002) (7)
- Expression and translocation of glucose isomerase as a fusion protein in E coli (2004) (7)
- Dynamic transcriptional response of Saccharomyces cerevisiae cells to copper (2020) (7)
- CLUSTERnGO: a user-defined modelling platform for two-stage clustering of time-series data (2015) (7)
- Exometabolic and transcriptional response in relation to phenotype and gene copy number in respiration‐related deletion mutants of S. cerevisiae (2008) (6)
- Modeling of the induced expression for high-level production of a foreign protein by recombinant E. coli under the control of the T7 phage promoter (2003) (6)
- Effect of the co-expression of methyltransferase activity on extracellular production of Taq I restriction endonuclease in recombinant E. coli cells (2001) (5)
- Studies on fermentation with recombinant yeast cells: plasmid stability and kinetics of biomass and protein production (2000) (5)
- Insights Into the Mechanism of Anticancer Drug Imatinib Revealed Through Multi-Omic Analyses in Yeast. (2020) (5)
- A novel 13 Bp deletion in the 3'UTR of the beta-globin gene causes beta-thalassemia in a Turkish patient. (1993) (5)
- SCREENING OF DELETIONS AND RFLP ANALYSIS IN TURKISH DUCHENNE AND BECKER MUSCULAR DYSTROPHY FAMILIES BY PCR (1993) (3)
- A Comparative Study on the Recovery of EcoRI Endonuclease from Two Different Genetically Modified Strains of Escherichia coli (2001) (3)
- The effect of cycloheximide on nuclear uH2A content (1984) (3)
- Isolation of protein uH2A using a one step preparative gel electrophoresis. (1984) (2)
- Time-dependent re-organization of biological processes by the analysis of the dynamic transcriptional response of yeast cells to doxorubicin. (2021) (2)
- High salt effect on RNA synthesis in Krebs ascites tumor cells (1982) (2)
- The global transcriptional response of a raw starch-degrading amylolytic Saccharomyces cerevisiae strain to oxygen limitation and genetic modification (2016) (1)
- Comparison of industrial Saccharomyces cerevisiae strains for second generation bioethanol production (2009) (1)
- Investigating the fermentation dynamics structure of recombinant yeast YPB-G (2003) (1)
- 3.1.40Fermentation performances of amylolytic Saccharomyces cerevisiae integrands developed for bioethanol production (2009) (1)
- Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis. (2019) (1)
- Modeling of recombinant yeast cells: reduction of phase space. (1997) (1)
- Techniques and technologies for detection of genomic abnormalities (2000) (0)
- Transcriptional and metabolic response of Saccharomyces cerevisiae to a nutritional perturbation when under stress (2007) (0)
- Structural robustness of protein interaction networks are due to modularity (2005) (0)
- Gene expression CLUSTERnGO : a user-defined modelling platform for two-stage clustering of time-series data (2016) (0)
- Analysis of copper homeostasis in yeast (2012) (0)
- Biomass composition: the “elephant in the room” of metabolic modelling (2015) (0)
- A novel frameshift mutation: deletion of C in codons 74/75 of the beta-globin gene causes beta zero-thalassemia in a Turkish patient. (1992) (0)
- Haplotype analysis in autosomal recessive polycystic kidney disease (ARPKD) families and the determination of allele frequencies of used markers in the Turkish population (2003) (0)
- Construction of amylolytic nuclear petite Saccharomyces cerevisiae strains for bioethanol production by SSF (2007) (0)
- Integrative genome-wide analysis of long-term effects of doxorubicin on yeast cells (2018) (0)
- Investigating the transcriptional differences of amylolytic Saccharomyces cerevisiae strains developed for bioethanol production via a systems based approach (2012) (0)
- Identification of candidate genes related to ethanol tolerance in Saccharomyces cerevisiae via a systems based modular approach (2012) (0)
- Research data supporting "CLUSTERnGO: a user-defined modelling platform for two-stage clustering of time-series data" (2015) (0)
- An integrative network based approach to analyze Type 2 diabetes (2010) (0)
- Short-and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment w (2012) (0)
- Modularity of type 2 diabetes related interactome map with transcriptional analyses (2009) (0)
- Analysis of infertile brothers with congenital bilateral absence of vas deferens for mutations in the CFTR gene (1999) (0)
- Saccharomyces cerevisiae adapted to grow in the presence of low-dose rapamycin exhibit altered amino acid metabolism (2018) (0)
- Modular organization of cardiovascular disease related protein interaction network (2009) (0)
- Human Gene Mutations (1998) (0)
- 4.3.02Integrative analysis of type 2 diabetes protein interaction network and OMIM database reveals associations between complex disorders (2009) (0)
- Doxorubicin induces an extensive transcriptional and metabolic rewiring in yeast cells (2018) (0)
- Transcriptomic response of yeast cells to ATX1 deletion under different copper levels (2016) (0)
- Integration of cardiovascular disease protein interaction network and OMIM database (2009) (0)
- Reconstruction and Modular Analysis of TOR Signaling Network in S. cerevisiae (2012) (0)
- Binding of protein uH2A and Histone H2A to DNA (1989) (0)
- Supporting Data for "Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis" (2020) (0)
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