Beverley A. Orser
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Beverley A. Orser's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science Stanford University
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Why Is Beverley A. Orser Influential?
(Suggest an Edit or Addition)According to Wikipedia, Beverley Anne Orser is a Canadian anesthesiologist. As a professor at the University of Toronto, Orser was elected a member of the National Academy of Medicine for "her discovery of the unique pharmacological properties of extrasynaptic GABA-A receptors and their mechanistic role in anesthetic- and inflammation-induced impairment of memory, and for her leadership in academic anesthesiology.
Beverley A. Orser's Published Works
Published Works
- Communication failures in the operating room: an observational classification of recurrent types and effects (2004) (1232)
- Evaluation of a preoperative checklist and team briefing among surgeons, nurses, and anesthesiologists to reduce failures in communication. (2008) (598)
- Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors (2004) (518)
- Emerging molecular mechanisms of general anesthetic action. (2005) (505)
- Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. (2001) (387)
- G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors (1999) (381)
- The Prevention of Chronic Postsurgical Pain Using Gabapentin and Pregabalin: A Combined Systematic Review and Meta-Analysis (2012) (366)
- Inhaled Anesthetics and Immobility: Mechanisms, Mysteries, and Minimum Alveolar Anesthetic Concentration (2003) (321)
- Multiple Mechanisms of Ketamine Blockade of N‐methyl‐D‐aspartate Receptors (1997) (316)
- Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors. (2004) (289)
- Anesthetic neurotoxicity--clinical implications of animal models. (2015) (275)
- Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia (2009) (265)
- Getting teams to talk: development and pilot implementation of a checklist to promote interprofessional communication in the OR (2005) (265)
- Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. (2013) (230)
- Inhibition by propofol (2,6 di‐isopropylphenol) of the N‐methyl‐D‐aspartate subtype of glutamate receptor in cultured hippocampal neurones (1995) (228)
- Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A (1994) (217)
- α5GABAA Receptors Mediate the Amnestic But Not Sedative-Hypnotic Effects of the General Anesthetic Etomidate (2006) (216)
- A D2 Class Dopamine Receptor Transactivates a Receptor Tyrosine Kinase to Inhibit NMDA Receptor Transmission (2002) (209)
- Medication errors in anesthetic practice: a survey of 687 practitioners (2001) (205)
- Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. (2003) (192)
- The General Anesthetic Propofol Slows Deactivation and Desensitization of GABAA Receptors (1999) (191)
- A GABAergic system in airway epithelium is essential for mucus overproduction in asthma (2007) (189)
- Tranexamic acid–associated seizures: Causes and treatment (2015) (164)
- α5GABAA Receptor Activity Sets the Threshold for Long-Term Potentiation and Constrains Hippocampus-Dependent Memory (2010) (162)
- Memory Deficits Induced by Inflammation Are Regulated by α5-Subunit-Containing GABAA Receptors (2012) (149)
- Recommendations for Endotracheal Intubation of COVID-19 Patients (2020) (149)
- Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group (2018) (148)
- Selective Enhancement of Tonic GABAergic Inhibition in Murine Hippocampal Neurons by Low Concentrations of the Volatile Anesthetic Isoflurane (2004) (148)
- Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. (2012) (147)
- Programming errors contribute to death from patient-controlled analgesia: case report and estimate of probability (2003) (140)
- Sustained increase in α5GABAA receptor function impairs memory after anesthesia. (2014) (129)
- Silence, power and communication in the operating room (2009) (125)
- Towards safer interprofessional communication: Constructing a model of “utility” from preoperative team briefings (2006) (123)
- Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons* (2003) (118)
- Modulation of NMDA Receptors by Pituitary Adenylate Cyclase Activating Peptide in CA1 Neurons Requires Gαq, Protein Kinase C, and Activation of Src (2005) (118)
- Diarylamidines: High potency inhibitors of acid-sensing ion channels (2010) (116)
- Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery. (2019) (115)
- An anaesthetic drug error: minimizing the risk (1994) (115)
- TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations (2007) (109)
- Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. (1998) (104)
- GABAA receptor subtypes underlying general anesthesia (2008) (102)
- α5GABAA Receptors Regulate the Intrinsic Excitability of Mouse Hippocampal Pyramidal Neurons (2007) (102)
- Short-term Memory Impairment after Isoflurane in Mice Is Prevented by the &agr;5 &ggr;-Aminobutyric Acid Type A Receptor Inverse Agonist L-655,708 (2010) (101)
- Intraoperative awareness: from neurobiology to clinical practice. (2011) (100)
- Intubation of SARS patients: infection and perspectives of healthcare workers (2006) (98)
- Evaluation of a preoperative team briefing: a new communication routine results in improved clinical practice (2011) (87)
- Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases (2012) (82)
- Etomidate Targets α5 γ-Aminobutyric Acid Subtype A Receptors to Regulate Synaptic Plasticity and Memory Blockade (2009) (78)
- Perioperative Neurocognitive Disorder: State of the Preclinical Science. (2020) (77)
- In CA1 Pyramidal Neurons of the Hippocampus Protein Kinase C Regulates Calcium-Dependent Inactivation of NMDA Receptors (2000) (71)
- Altered expression of δGABAA receptors in health and disease (2015) (66)
- Pharmacological enhancement of δ-subunit-containing GABAA receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice (2011) (66)
- Extrasynaptic GABAA receptors are critical targets for sedative-hypnotic drugs. (2006) (66)
- The Effects of Midazolam on Propofol-Induced Anesthesia: Propofol Dose Requirements, Mood Profiles, and Perioperative Dreams (1997) (63)
- The Influence of Glutamate Receptor 2 Expression on Excitotoxicity in GluR2 Null Mutant Mice (2001) (59)
- Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator (2016) (56)
- Inhibition of &agr;5 &ggr;-Aminobutyric Acid Type A Receptors Restores Recognition Memory After General Anesthesia (2012) (53)
- Gabapentin reduces preoperative anxiety and pain catastrophizing in highly anxious patients prior to major surgery: a blinded randomized placebo-controlled trial (2013) (53)
- Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice. (1999) (52)
- Anesthesia-related medication error: time to take action (2004) (51)
- Acutely increasing δGABAA receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus (2013) (49)
- Dystonic reaction to propofol attenuated by benztropine (cogentin). (2002) (48)
- Platelet-derived Growth Factor Receptor-induced Feed-forward Inhibition of Excitatory Transmission between Hippocampal Pyramidal Neurons* (1999) (47)
- α5 Subunit-containing GABAA receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation (2010) (47)
- Blockade of AMPA Receptors and Volatile Anesthetics: Reduced Anesthetic Requirements in GluR2 Null Mutant Mice for Loss of the Righting Reflex and Antinociception but Not Minimum Alveolar Concentration (2001) (46)
- Perioperative Medication Errors: Building Safer Systems. (2016) (46)
- Awareness during anesthesia (2008) (45)
- Inhibition of learning and memory by general anesthetics (2011) (45)
- General anaesthetics and their effects on GABA(A) receptor desensitization. (1998) (45)
- γ‐aminobutyric acid type A receptors that contain the δ subunit promote memory and neurogenesis in the dentate gyrus (2013) (42)
- Positive allosteric modulators of AMPA receptors reduce proton-induced receptor desensitization in rat hippocampal neurons. (2001) (42)
- Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG (2000) (42)
- Ketamine Increases the Function of &ggr;-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons (2017) (42)
- Depth-of-anesthesia monitor and the frequency of intraoperative awareness. (2008) (40)
- Lifting the fog around anesthesia. (2007) (39)
- Paradoxical effects of interprofessional briefings on OR team performance (2008) (39)
- Design and screening of ASIC inhibitors based on aromatic diamidines for combating neurological disorders. (2010) (39)
- Propofol and thiopental anesthesia: a comparison of the incidence of dreams and perioperative mood alterations. (1994) (39)
- α5GABAA receptor deficiency causes autism‐like behaviors (2016) (37)
- SmartTots Update Regarding Anesthetic Neurotoxicity in the Developing Brain. (2018) (37)
- Review article: Improving drug safety for patients undergoing anesthesia and surgery (2013) (36)
- Alpha5GABAA receptors regulate the intrinsic excitability of mouse hippocampal pyramidal neurons. (2007) (35)
- Disruption of coherent oscillations in inhibitory networks with anesthetics: role of GABA(A) receptor desensitization. (2002) (35)
- The physiological properties and therapeutic potential of alpha5-GABAA receptors. (2009) (35)
- Isobolographic Analysis of the Interactions between Midazolam and Propofol at GABAA Receptors in Embryonic Mouse Neurons (1998) (34)
- Inflammation Increases Neuronal Sensitivity to General Anesthetics (2016) (33)
- Multiple sites of action of neomycin, Mg2+ and spermine on the NMDA receptors of rat hippocampal CA1 pyramidal neurones (1998) (32)
- Non‐steroidal anti‐inflammatory drugs increase insulin release from beta cells by inhibiting ATP‐sensitive potassium channels (2007) (32)
- Repeated intermittent alcohol exposure during the third trimester-equivalent increases expression of the GABAA receptor δ subunit in cerebellar granule neurons and delays motor development in rats (2014) (31)
- GABA promotes β‐cell proliferation, but does not overcome impaired glucose homeostasis associated with diet‐induced obesity (2018) (31)
- Dexmedetomidine Prevents Excessive &ggr;-Aminobutyric Acid Type A Receptor Function after Anesthesia (2018) (31)
- The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations (2010) (30)
- Tyrosine kinases enhance the function of glycine receptors in rat hippocampal neurons and human α1β glycine receptors (2002) (28)
- α5GABAA Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia (2017) (28)
- Potentiation of GABAA receptor activity by volatile anaesthetics is reduced by α5GABAA receptor-preferring inverse agonists. (2013) (28)
- Modulation of NMDA receptors. (1998) (27)
- Distinct properties of murine α5 γ‐aminobutyric acid type a receptors revealed by biochemical fractionation and mass spectroscopy (2009) (26)
- Uptake of a team briefing in the operating theatre: a Burkean dramatistic analysis. (2009) (26)
- An open label pilot study of a dexmedetomidine‐remifentanil‐caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study (2018) (26)
- Gabapentin Increases a Tonic Inhibitory Conductance in Hippocampal Pyramidal Neurons (2006) (25)
- Hyperpolarization-Activated Current (Ih) Is Reduced in Hippocampal Neurons from Gabra5−/− Mice (2013) (24)
- Isoflurane Regulates Atypical Type-A &ggr;-Aminobutyric Acid Receptors in Alveolar Type II Epithelial Cells (2013) (24)
- Platelet glycoprotein IIb/IIIa inhibitors: overview and implications for the anesthesiologist. (2002) (24)
- Hydrogen Peroxide Increases GABAA Receptor-Mediated Tonic Current in Hippocampal Neurons (2014) (23)
- Medication safety in anesthetic practice: first do no harm (2000) (23)
- Ketamine augmentation for major depressive disorder and suicidal ideation: Preliminary experience in an inpatient psychiatry setting. (2018) (23)
- Thalamic δ-Subunit Containing GABAA Receptors Promote Electrocortical Signatures of Deep Non-REM Sleep But Do Not Mediate the Effects of Etomidate at the Thalamus In Vivo (2014) (23)
- Gabapentin increases expression of δ subunit-containing GABAA receptors (2019) (22)
- Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward (2022) (21)
- Gabapentin does not reduce preoperative anxiety when given prior to total hip arthroplasty. (2010) (21)
- Insulin Increases the Potency of Glycine at Ionotropic Glycine Receptors (2007) (21)
- Mechanisms of general anesthesia (2002) (20)
- Desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors facilitates use-dependent inhibition by pentobarbital. (2003) (20)
- Functional Modifications of Acid-Sensing Ion Channels by Ligand-Gated Chloride Channels (2011) (19)
- Medication safety in the operating room: teaming up to improve patient safety. (2008) (18)
- Magnesium deficiency increases ketamine sensitivity in rats (1997) (18)
- Thrombocytopenia and cocaine abuse. (1991) (18)
- Predictive factors for sleep apnoea in patients on opioids for chronic pain (2019) (18)
- Improving Access to Safe Anesthetic Care in Rural and Remote Communities in Affluent Countries. (2019) (18)
- Reduced expression of α5GABAA receptors elicits autism-like alterations in EEG patterns and sleep-wake behavior. (2017) (17)
- “Seizing” the opportunity to understand antifibrinolytic drugs (2011) (16)
- α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells (2015) (15)
- Sedating ventilated COVID-19 patients with inhalational anesthetic drugs (2020) (15)
- Sleep and Anesthesia: Neural Correlates in Theory and Experiment (2012) (14)
- Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. (2017) (14)
- Canada needs a national strategy for anesthesia services in rural and remote regions (2020) (14)
- Propofol-induced neuroexcitation and receptor desensitization (1994) (14)
- Plasticity of synaptic glun receptors is required for the Src‐dependent induction of long‐term potentiation at CA3‐CA1 synapses (2011) (13)
- Obstetrical epidural anaesthesia in a Canadian outpost hospital (1988) (13)
- Reducing medication errors. (2000) (12)
- The sedative but not the memory-blocking properties of ethanol are modulated by α5-subunit-containing γ-aminobutyric acid type A receptors (2011) (12)
- Cellular / Molecular 5 GABAA Receptors Mediate the Amnestic But Not Sedative-Hypnotic Effects of the General Anesthetic Etomidate (2006) (11)
- High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors (2017) (11)
- &dgr;GABAA Receptors Are Necessary for Synaptic Plasticity in the Hippocampus: Implications for Memory Behavior (2016) (11)
- Medication error: a leading cause of anesthesia-related morbidity and mortality. (2007) (10)
- External compression of a nasotracheal tube due to the displaced bony fragments of multiple LeFort fractures. (2000) (10)
- New opportunities for anesthesia research in Canada (2002) (10)
- Targeting microglia to mitigate perioperative neurocognitive disorders. (2020) (9)
- Multimodal anesthesia and systems neuroscience: the new frontier. (2008) (9)
- Tyrosine kinases enhance the function of glycine receptors in rat hippocampal neurons and human alpha(1)beta glycine receptors. (2002) (9)
- Propofol-benzodiazepine interactions: insights from a “bench to bedside” approach (2001) (8)
- Propofol, seizure and antidepressants (1994) (8)
- Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats. (2016) (8)
- GABAA Receptor Theory of Perioperative Neurocognitive Disorders. (2019) (7)
- Managing Ebola: Lessons Learned from the SARS Epidemic. (2015) (7)
- Facial pain in the recovery room secondary to acute parotitis. (1990) (7)
- Pregabalin effective for the prevention of chronic postsurgical pain: really? Reply. (2013) (7)
- Insulin Decreases Isoflurane Minimum Alveolar Anesthetic Concentration in Rats Independently of an Effect on the Spinal Cord (2004) (6)
- Protocol for a prospective cohort study of assessing postoperative cognitive changes after total hip and knee arthroplasty in the Greater Toronto area (2019) (6)
- Modulation of AMPA receptors by a novel organic nitrate. (2001) (6)
- Propofol and Thiopental Anesthesia: A Comparison of the Incidence of Dreams and Perioperative Mood Alterations (1994) (6)
- Inhibition of a tonic inhibitory conductance in mouse hippocampal neurones by negative allosteric modulators of α5 subunit-containing γ-aminobutyric acid type A receptors: implications for treating cognitive deficits. (2020) (6)
- δ-Subunit Containing GABAA Receptors Modulate Respiratory Networks (2017) (6)
- GABAA Receptors Regulate the Intrinsic Excitability of Mouse Hippocampal Pyramidal Neurons (2007) (6)
- Nitrous oxide as a putative novel dual-mechanism treatment for bipolar depression: Proof-of-concept study design and methodology (2020) (6)
- Neurodevelopment after general anaesthesia in infants (2019) (6)
- Dantrolene sodium and heatstroke. (1992) (6)
- Reciprocal and activity-dependent regulation of surface AMPA and NMDA receptors in cultured neurons. (2009) (5)
- An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma. (2011) (5)
- Medication labels: for whose benefit? (1996) (4)
- Consensus statement on networks for high-quality rural anesthesia, surgery, and obstetric care in Canada (2022) (4)
- Inhibiting α5 Subunit-Containing γ-Aminobutyric Acid Type A Receptors Attenuates Cognitive Deficits After Traumatic Brain Injury. (2019) (4)
- Improving anesthesia care and pain medicine in rural Canada: nothing about us without us (2021) (4)
- Preventing delirium: beyond dexmedetomidine (2017) (4)
- DANTROLENE SODIUM AND HEATSTROKE. AUTHOR'S REPLY (1992) (4)
- Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol (2021) (4)
- Anesthesiology in the 21st century: our science is our destiny (2018) (3)
- Frequency switches in inhibitory networks with anesthetics (2001) (3)
- Locating and repurposing anesthetic machines as intensive care unit ventilators during the COVID-19 pandemic (2020) (3)
- Mechanisms of anesthesia: past, present, and a glimpse into the future (2011) (3)
- Anesthesiology: Resetting Our Sights on Long-term Outcomes: The 2020 John W. Severinghaus Lecture on Translational Science. (2021) (3)
- Chapter 19 – The structure and function of neurons (2006) (3)
- Drug safety in Canada: 2 steps forward, 1 step back (2006) (2)
- Inhibiting α5 Subunit-Containing γ-Aminobutyric Acid Type A Receptors Attenuates Cognitive Deficits After Traumatic Brain Injury. (2020) (2)
- Anesthesia research training: preparing for the future of our speciality (2016) (2)
- GABAergic Signaling in Health and Disease (2015) (2)
- Faculty Opinions recommendation of NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents. (2011) (2)
- The authors respond to “Nurse anesthesiologists” (2020) (2)
- Understanding Anesthesia-Induced Memory Loss (2015) (2)
- No community left behind: advancing rural anesthesia, surgery, and obstetric care in Canada (2022) (2)
- The Impact of Inflammation and General Anesthesia on Memory and Executive Function in Mice (2022) (2)
- Global PRoMiSe (Perioperative Recommendations for Medication Safety): protocol for a mixed-methods study (2020) (2)
- GABAA Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs (2022) (2)
- Proof-of-concept randomized controlled trial of single-session nitrous oxide treatment for refractory bipolar depression: Focus on cerebrovascular target engagement. (2022) (1)
- Cognitive deficits after general anaesthesia in animal models: a scoping review. (2022) (1)
- Symposium on ergonomics in drug delivery (1997) (1)
- Competence-Based Training and Immersion Virtual Reality: Paradigm-Shifting Advances in Medical Education. (2022) (1)
- The α5 GABAA receptor subunit confers resistance to isoflurane inhibition (2005) (1)
- Reconciling differences between in vitro and in vivo effects of propofol. (1996) (1)
- Physostigmine, propofol and the GABAA receptor (1998) (1)
- δ-Subunit Containing GABAA Receptors Modulate Respiratory Networks (2017) (1)
- Cognitive decline among older adults: A hidden preexisting condition and its role in ‘brain‐at‐risk’ surgical patients (2021) (1)
- Propranolol protection from bupivacaine toxicity (1992) (1)
- The International Anesthesia Research Society Coronavirus Disease 2019 Pandemic Scientific Advisory Board: Supporting a Pandemic of Positivity. (2021) (1)
- Preventing neuraxial administration of tranexamic acid. (2023) (1)
- Multiple binding sites for anaesthetics on the GABAA receptor (1996) (1)
- Learning fiberoptic intubation on a simple model transfers to the O.R. (2001) (1)
- Developing practice guidelines for anesthesia services in rural Canada: the importance of the family physician perspective (2020) (1)
- Improving Access to Safe Anesthetic Care in Rural and Remote Communities in Affluent Countries (2019) (1)
- DRUG ERRORS. AUTHORS' REPLY (1994) (1)
- DO POSTANESTHETIC MEMORY DEFICITS AND ALZHEIMER’S DISEASE SHARE A COMMON SIGNALING PATHWAY? (2016) (0)
- CELL-SPECIFIC GENE EXPRESSION PATTERN OF α5-SUBUNIT CONTAINING γ-AMINOBUTYRIC ACID SUBTYPE A RECEPTORS IN HUMAN AND MOUSE PREFRONTAL CORTEX (2018) (0)
- Treatment of Global Cerebral Ischemia by Virally-Mediated shRNA Suppression of TRPM7 Channels (1970) (0)
- Are epsins a therapeutic target for tumor (2012) (0)
- Reply (1) (1994) (0)
- The anesthesia workforce in Canada: a methodology to identify physician anesthesia providers using health administrative data (2023) (0)
- In Reply. (2016) (0)
- S.24.03 Role of extrasynaptic GABA in hippocampus (2006) (0)
- Novel extrasynaptic gabaa receptor populations in murine spinal cord (2006) (0)
- BENEFICIAL EFFECTS OF METHYLPHENIDATE ON VERBAL WORKING MEMORY IN CHILDREN WITH ADHD (2010) (0)
- Rat Hippocampal Neurons Reduce Proton-Induced Receptor Desensitization in Positive Allosteric Modulators of AMPA Receptors (2006) (0)
- A Nonselective Cation Channel in Adult Alveolar Epithelial Cells (1994) (0)
- Editorial: Innovative approaches for assessing and improving perioperative neurocognitive disorders (2022) (0)
- Mitochondrial metabolism regulates GABAergic neurotransmission in cerebellar granule cells (2014) (0)
- Canadian Anesthesiologists’ Society 2011 Royal College Lecture: Anesthesiology: A Profession at a Crossroads (2012) (0)
- Faculty Opinions recommendation of Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. (2011) (0)
- Book reviews (1998) (0)
- Faculty Opinions recommendation of Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog. (2007) (0)
- Before the Next Wave: Reducing Viral Infections Among Health Care Workers Performing Tracheal Intubation. (2022) (0)
- Faculty Opinions recommendation of Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons. (2010) (0)
- Inhibition of a tonic inhibitory conductance in mouse hippocampal neurons by negative allosteric modulators of α5GABAA receptors: implications for treating cognitive deficits Running Title: Comparing the effect of α5GABAA receptor NAMs (2021) (0)
- Perioperative Neurocognitive Screening Tools for At-Risk Surgical Patients. (2021) (0)
- The amnestic and sedative-hypnotic properties of etomidate in mice can be dissociated based on gaba(a) receptor subtype pharmacology (2006) (0)
- 2020 Severinghaus Lecture on Translational Science: Reply. (2021) (0)
- Cognitive decline among older adults: A hidden preexisting condition and its role in â•Ÿbrainâ•’atâ•’riskâ•Ž surgical patients (2021) (0)
- A tonic inhibitory conductance in murine spinal neurons: a novel site for anesthetics? (2006) (0)
- In Memoriam: Brian Kavanagh, 1962 to 2019. (2019) (0)
- Faculty Opinions recommendation of Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice. (2009) (0)
- P.1.h.023 Molecular pathways responsible for NMDA receptor-mediated behavioural plasticity (2016) (0)
- UPDATE: SNIPPETS OF SCIENCE (2007) (0)
- Programming errors from patient-controlled analgesia. Authors' reply (2003) (0)
- A-type gamma-aminobutyric acid receptor (gabaar) and glutamic acid decarboxylase (gad) in type ii pneumocytes (2006) (0)
- Propofol potentiates GABAergic currents by slowing the dissociation of agonist from ligand-bound preopen and desensitized states (1999) (0)
- Brief Research Report Gabapentin Does Not Reduce Preoperative Anxiety When Given Prior to Total Hip Arthroplasty (2010) (0)
- In reply: Initiatives to support rural access to anesthesia (2022) (0)
- Blockade of Tonic and Synaptic GABAergic Current in Murine Hippocampal Neurons Reveals Two Populations of GABA-A Receptors: [2002][A-768] (2002) (0)
- Current in Cultured Hippocampal Neurons -Sensing Cation 2+ Effect of Lamotrigine on the Ca (2015) (0)
- Author response for "Cognitive decline among older adults: A hidden preexisting condition and its role in ‘brain‐at‐risk’ surgical patients" (2021) (0)
- 432. Baseline Resting-State Functional Connectivity is Associated With Bipolar Depression Symptom Reduction Following Treatment With Nitrous Oxide (2023) (0)
- Insulin Enhancement of Glycine Receptors in Spinal Neurons: A Novel Strategy for Pain Therapy: [2002][A-769] (2002) (0)
- Cellular and Molecular Effects of General Anesthetics in the Brain (2011) (0)
- Faculty Opinions recommendation of Presynaptic miniature GABAergic currents in developing interneurons. (2010) (0)
- Faculty Opinions recommendation of Allosteric potentiation of glycine receptor chloride currents by glutamate. (2010) (0)
- Unlocking the Mechanisms of Anesthesia. (2016) (0)
- Editorial Propofol-induced neuroexcitation and (1994) (0)
- Tranexamic acid-associated seizures: Causes and treatment: TXA-Associated Seizures (2015) (0)
- SLOW BLOCKADE OF NMDA CHANNELS BY KETAMINE (1991) (0)
- Platelet Glycoprotein IIb/IIIa Inhibitors: Overview and Implications for the Anesthesiologist (2002) (0)
- Anesthetic sensitivity is reduced in hippocampal pyramidal neurons from GABAA receptor α5 subunit null mutant mice (2005) (0)
- In Response (2020) (0)
- Laboratory Investigation Magnesium deficiency increases ketamine sensitivity in rats (1997) (0)
- GABA promotes b -cell proliferation, but does not overcome impaired glucose homeostasis associated with diet-induced obesity (2019) (0)
- In Response (1995) (0)
- Desensitization Receptor A Networks With Anesthetics: Role of GABA Disruption of Coherent Oscillations in Inhibitory (2015) (0)
- PHYSOSTIGMINE, PROPOFOL AND THE GABAA RECEPTOR. AUTHOR'S REPLY (1998) (0)
- Musings from an Unlikely Clinician-Scientist: 2018 American Society of Anesthesiologists Excellence in Research Award. (2019) (0)
- Sevoflurane and lipopolysaccharide-induced inflammation differentially affect γ-aminobutyric acid type A receptor-mediated tonic inhibition in the hippocampus of male mice. (2022) (0)
- Correction: No community left behind: advancing rural anesthesia, surgery, and obstetric care in Canada (2022) (0)
- Learning together to safely intubate patients with COVID-19. (2020) (0)
- Abstracts (1998) (0)
- Inflammation and GABA-A receptors (2013) (0)
- Abstracts (1998) (0)
- Strains of Inbred Mice Tuning of LTP at Hippocampal Synapses of Specific Differential Maintenance and Frequency-Dependent (2015) (0)
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