Beverley Pearson Murphy
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Canadian endocrinologist
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(Suggest an Edit or Addition)According to Wikipedia, Beverley E. Pearson Murphy, MD, was a Canadian endocrinologist and professor emeritus at McGill University. Born in Toronto, she earned a B.A. in science from the University of Toronto in 1952, followed by an M.D. in 1956. She earned a masters’ degree in Experimental Medicine at McGill University in 1960, completing her residency at the Royal Victoria Hospital, and was awarded a PhD in Investigative Medicine from McGill in 1964.
Beverley Pearson Murphy's Published Works
Published Works
- Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. (1967) (2086)
- DETERMINATION OF THYROXINE UTILIZING THE PROPERTY OF PROTEIN-BINDING. (1964) (356)
- In vitro metabolism of prednisolone, dexamethasone, betamethasone, and cortisol by the human placenta. (1977) (262)
- Steroids and depression (1991) (260)
- Conversion of maternal cortisol to cortisone during placental transfer to the human fetus. (1974) (249)
- Clinical evaluation of urinary cortisol determinations by competetive protein-binding radioassay. (1968) (212)
- Ontogeny of cortisol-cortisone interconversion in human tissues: a role for cortisone in human fetal development. (1981) (175)
- "Sephadex" column chromatography as an adjunct to competitive protein binding assays of steroids. (1971) (148)
- Antiglucocorticoid therapies in major depression: A review (1997) (139)
- Response to steroid suppression in major depression resistant to antidepressant therapy. (1991) (138)
- Application of the Property of Protein-Binding to the Assay of Minute Quantities of Hormones and Other Substances (1964) (134)
- Binding of testosterone and estradiol in plasma. (1968) (112)
- Possible use of glucocorticoid receptor antagonists in the treatment of major depression: preliminary results using RU 486. (1993) (111)
- Does the human fetal adrenal play a role in parturition? (1973) (106)
- Cortisol in amniotic fluid during human gestation. (1975) (103)
- Clinical evaluation of a new method for the determination of serum thyroxine. (1966) (102)
- Human fetal serum cortisol levels related to gestational age: evidence of a midgestational fall and a steep late gestational rise, independent of sex or mode of delivery. (1982) (101)
- Cortisol and cortisone levels in the cord blood at delivery of infants with and without the respiratory distress syndrome. (1974) (98)
- Competitive binding assay for adenosine 3',5'-monophosphate employing a bovine adrenal protein: application to urine, plasma and tissues. (1972) (86)
- DETERMINATION OF PLASMA CORTICOIDS BY COMPETITIVE PROTEIN-BINDING ANALYSIS USING GEL FILTRATION. (1964) (84)
- Lack of specificity of cortisol determinations in human urine. (1981) (83)
- Steroid levels in the human fetus: cortisol and cortisone. (1972) (80)
- The maternal-fetal cortisol gradient during pregnancy and at delivery. (1977) (79)
- Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy. (2001) (78)
- Chorionic membrane as an extra-adrenal source of foetal cortisol in human amniotic fluid (1977) (77)
- The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment (1995) (76)
- Treatment of major depression with steroid suppressive drugs (1991) (75)
- Cortisol and cortisone in human fetal development. (1979) (63)
- Cortisol production and inactivation by the human lung during gestation and infancy. (1978) (55)
- Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum (2000) (51)
- Efficacy of light versus tryptophan therapy in seasonal affective disorder. (1998) (48)
- Inhibition of testosterone metabolism in the human prostate. (1974) (45)
- Androgens in the human fetus (1974) (44)
- Neuroendocrine Responses to Inhibitors of Steroid Biosynthesis in Patients with Major Depression Resistant to Antidepressant Therapy (1998) (43)
- Double-blind randomized crossover trial of luteal phase estrogens (premarin®) in the premenstrual syndrome (PMS) (1990) (43)
- Cortisol-cortisone interconversion in human fetal lung: contrasting results using explant and monolayer cultures suggest that 11 beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) comprises two enzymes. (1982) (42)
- Urinary Free Cortisol Determinations: What They Measure (2002) (40)
- Non-chromatographic radiotransinassay for cortisol: application to human adult serum, umbilical cord serum, and amniotic fluid. (1975) (38)
- How much "UFC" is really cortisol? (2000) (38)
- Cortisol levels in maternal venous and umbilical cord arterial and venous serum at vaginal delivery. (1976) (38)
- Methodological problems in competitive protein-binding techniques; the use of sephadex column chromatography to separate steroids. (1970) (35)
- Steroid arteriovenous differences in umbilical cord plasma: evidence of cortisol production by the human fetus in early gestation. (1973) (34)
- Conjugated glucocorticoids in amniotic fluid and fetal lung maturation. (1978) (34)
- Human fetal serum cortisol levels at delivery: a review. (1983) (34)
- Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome (2004) (32)
- The Pathophysiologic Significance of Hyperadrenocorticism: Antiglucocorticoid Strategies (1993) (29)
- Amniotic-fluid cortisol and human fetal lung maturation. (1977) (29)
- SERUM OESTROGENS AND PROGESTERONE IN MOTHER AND INFANT AT DELIVERY (1977) (27)
- The use of sephadex LH-20 column chromatography to separate unconjugated steroids. (1975) (27)
- Lack of specificity of urinary free cortisol determinations: why does it continue? (1999) (26)
- Lack of specificity of urinary free cortisol determinations: why does it continue? (1999) (26)
- Specificity of the progesterone-binding globulin of the guinea pig. (1974) (26)
- Further studies of the specificity of the sex hormone-binding globulin of human plasma. (1970) (25)
- CORTISOL IN AMNIOTIC FLUID DURING HUMAN GESTATION (1975) (25)
- Specificity of human 11β-hydroxysteroid dehydrogenase (1981) (25)
- Amniotic fluid thyroid hormone concentrations during human gestation. (1980) (25)
- Conversion of cortisol to cortisone by the human uterus and its reversal in pregnancy. (1977) (24)
- Evidence of cortisol deficiency at birth in infants with the respiratory distress syndrome. (1974) (24)
- Changing patterns of circulating corticosteroids in rabbits following prolonged treatment with ACTH. (1972) (22)
- The effects of various hormones on human chorionic gonadotropin production in early and late placental explant cultures. (1988) (21)
- Demonstration of novel compounds in human fetal tissues and a consideration of their possible role in parturition. (1981) (20)
- Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test (2008) (20)
- Fetal Metabolism of Cortisol (1983) (19)
- Competitive binding to multiple stereospecific binding agents as a means of verifying the identity of a ligand application to cortisol in human umbilical cord blood. (1973) (18)
- Chorionic membrane as an extra-adrenal source of foetal cortisol in human amniotic fluid (1977) (18)
- Cortisol production and metabolism in the human fetus and its reflection in the maternal urine. (1980) (17)
- CLINICAL STUDIES UTILIZING A NEW METHOD FOR THE SERIAL DETERMINATION OF PLASMA CORTICOIDS. (1964) (15)
- Investigation of factors influencing 11 beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) activity in midgestational human fetal lung monolayer and explant cultures. (1984) (14)
- Metabolism of progesterone by human lymphocytes: production of neuroactive steroids. (1997) (14)
- In vitro tests of thyroid function. (1971) (13)
- The influence of serum proteins on the metabolism of cortisol by the human placenta. (1979) (13)
- Androgens in the human fetus. (1974) (12)
- The effects of human chorionic gonadotropin on growth and steroidogenesis of the human fetal adrenal gland in vitro. (1987) (12)
- Isolation of cytoplasmic glucocorticoid-binding protein(s) from rat liver by means of affinity chromatography, and its partial characterization. (1973) (12)
- Potentiation of fluoxetine by aminoglutethimide, an adrenal steroid suppressant. in obsessive-compulsive disorder resistant to ssris: A case report (1996) (11)
- Contrasting effects of 5α- and 5β-pregnane-3,20-dione on the motor activity of ovariectomized rats (1987) (11)
- The absorption by the human fetus of intra-amniotically injected cortisol. (1982) (11)
- Mass spectrometric identification of testosterone, androstenedione, dehydroepiandrosterone, dihydrotestosterone, and androstanediol in human peripheral plasma. (1973) (10)
- In vitro stimulation of placental progesterone production by 19-nortestosterone and C19 steroids in early human pregnancy. (1992) (9)
- Pitfalls in the assay of cortisol. (1980) (9)
- Interaction of gelatin with stereospecific binding proteins and its enhancement of competitive binding assays (1974) (8)
- Plasma 17α hydroxyprogesterone: an improved radioassay method (1975) (8)
- Profiles of ligands of sex hormone binding globulin in human serum. (1988) (8)
- Measurement of ring A-reduced progesterone metabolites by enzyme-linked immunoassay with colorimetric detection: baseline levels of six metabolites, including pregnanolone, in male rat plasma. (2009) (7)
- Confirmation of the presence of dihydrotestosterone in human plasma by mass spectrometry (1971) (7)
- The premenstrual syndrome and its treatment (1991) (6)
- Influence of 19-nortestosterone and androgens on progesterone biosynthetic enzymes in early human placental explants (1992) (6)
- Relative binding of certain steroids of low polarity to human sex hormone—Binding globulin: Strong binding of 2-methoxyestrone, a steroid lacking the 17β-oh group (1986) (6)
- A case of seasonal bipolar disorder exacerbated by Cushing's disease. (2005) (5)
- RADIOISOTOPES IN MEDICINE: IN VITRO STUDIES. Proceedings of a Symposium held at the Oak Ridge Associated Universities, November 13--16, 1967. AEC Symposium Series 13. (1968) (5)
- Low polarity ligands of sex hormone-binding globulin in pregnancy. Part II--Identification. (1989) (5)
- Thyroid function in epileptic mothers and their infants at birth. (1985) (5)
- Comparison of glucocorticoid conjugates with other indexes of fetal maturation. (1979) (4)
- An introduction to anorexia nervosa and bulimia nervosa. (2003) (4)
- DETERMINATION OF THYROXINE BY COMPETITIVE PROTEIN-BINDING ANALYSIS EMPLOYING AN ANION-EXCHANGE RESIN AND RADIOACTIVE THYROXINE. (1965) (4)
- One-tube radiotransinassay for determination of cortisol at ambient temperature. (1987) (4)
- Effect of maternal serum on viability and function of early human placental explants. (1993) (4)
- Corticosteroid-Binding Globulin (Transcortin)* (2007) (4)
- Low polarity ligands of sex hormone-binding globulin in pregnancy. Part I--Characterization. (1989) (4)
- Radioenzymaticassay for some substrates and inhibitors of human placental 11-hydroxysteroid dehydrogenase. (1982) (3)
- Commercial radioimmunoassays do not measure urinary free cortisol accurately and should not be used for physiological studies. (2003) (3)
- Alcohols which have been in contact with any plastics may interfere in radioimmunoassays of progesterone (2009) (3)
- Neuroactive steroid levels in patients with panic disorder. (2003) (3)
- Does sex hormone-binding globulin play a role in the transport of estradiol in vivo? (1984) (3)
- Plasma cortisol concentrations in women with menopausal flushes. (1985) (2)
- Nuclear in vitro procedures. I. Competitive protein-binding radioassays. II. Functional radioassays and other techniques (1972) (2)
- Specificity of human 11 beta-hydroxysteroid dehydrogenase. (1981) (2)
- Commercial radioimmunoassays do not measure urinary free cortisol accurately and should not be used for physiological studies. (2003) (2)
- Identification of 20 alpha-hydroxy-5 alpha-pregnan-3-one and 20 beta-hydroxy-5 alpha-pregnan-3-one in human pregnancy urine. (1989) (2)
- The Determination of Plasma Levels of Corticoids and Their Diagnostic Significance (1967) (2)
- Identification of 20α-hydroxy-5α-pregnan-3-one and 20β-hydroxy-5α-pregnan-3-one in human pregnancy urine (1989) (2)
- The influence of various steroids on the binding of methyltrienolone (R1881) to human placenta: evidence for a second steroid-binding site which stabilizes the R1881 binding site. (1989) (2)
- Urinary free cortisol levels in PTSD offspring (2003) (2)
- Psychotropic effects of steroid synthesis inhibitors in refractory depression (1994) (1)
- Risks of postmenopausal hormone replacement. Authors' reply (2002) (1)
- Changes in spleen weight, cyclic-AMP content, and serum-corticosterone levels of rats in response to CO2. (1974) (1)
- Effect of maternal serum on viability and function of early human placental explants (1993) (1)
- Cortisol levels of infants at birth. (1982) (1)
- THE USE OF SEPHADEX LH-20 COLUMN CHROMATOGRAPHY TO SEPARATE UNCONJUGATED STEROIDS (1976) (1)
- Cortisol levels of infants at birth (1982) (1)
- The separation of epinephrine from norepinephrine and dopamine from DOPA on Sephadex G-10 (1973) (1)
- Inhibition of a parathyroid hormone-stimulated renal adenylate cyclase by cyclic AMP. (1975) (1)
- Allopregnanolone assays. (2001) (1)
- Endocrine responses to antiglucocorticoid strategies in refractory depression (1994) (1)
- 289. Investigation of factors influencing 11-hydroxysteroid dehydrogenase activity in human fetal lung (1982) (0)
- Plasma 17alpha hydroxyprogesterone: an improved radioassay method. (1975) (0)
- Plasma and urinary corticosteroids and androgens in c3h mice with and without mammary tumor. Abstr. (1970) (0)
- Theoretical Basis for Response to Steroid Suppression in Major Depression (1992) (0)
- Fetal cortisol levels at delivery: reply to Dr. Solomon's reply. (1983) (0)
- Safety and Efficacy of High-Dose Droperidol in Agitated Patients (1992) (0)
- Relative binding of certain estrogens to sex hormone-binding globulin (SHBG) (1984) (0)
- 305 AMNIOTIC FLUID TRIIODOTHYRONINE AND CORTISOL CORRELATIONS FROM 10 TO 43 WEEKS GESTATION (1978) (0)
- Risks of Postmenopausal Hormone Replacement (2002) (0)
- Contrasting effects of 5 alpha- and 5 beta-pregnane-3,20-dione on the motor activity of ovariectomized rats. (1987) (0)
- 51. Physiologically available cortisol in the human fetus and mother (1975) (0)
- Risks of postmenopausal hormone replacement. (2002) (0)
- Neuroactive steroid levels in patients with panic disorder. (2003) (0)
- One-TubeRadiotransinassay forDetermination of Cortisol at AmbientTemperature (1987) (0)
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