Bin He
#185,138
Most Influential Person Now
Bin He's AcademicInfluence.com Rankings
Bin Hebiology Degrees
Biology
#15559
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#19566
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Virology
#400
World Rank
#409
Historical Rank
Molecular Biology
#2692
World Rank
#2733
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Biochemistry
#2734
World Rank
#2920
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Biology
Bin He's Degrees
- PhD Molecular Biology University of California, San Francisco
- Bachelors Biochemistry University of California, Berkeley
Why Is Bin He Influential?
(Suggest an Edit or Addition)Bin He's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The γ134.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the α subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase (1997) (696)
- Viruses, endoplasmic reticulum stress, and interferon responses (2006) (389)
- The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. (1997) (360)
- GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor (2004) (275)
- Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins (1998) (239)
- Control of TANK-binding Kinase 1-mediated Signaling by the γ134.5 Protein of Herpes Simplex Virus 1* (2009) (191)
- The γ134.5 Protein of Herpes Simplex Virus 1 Has the Structural and Functional Attributes of a Protein Phosphatase 1 Regulatory Subunit and Is Present in a High Molecular Weight Complex with the Enzyme in Infected Cells* (1998) (183)
- The 3C Protein of Enterovirus 71 Inhibits Retinoid Acid-Inducible Gene I-Mediated Interferon Regulatory Factor 3 Activation and Type I Interferon Responses (2010) (183)
- Induction of interleukin (IL)-8 gene expression by respiratory syncytial virus involves activation of nuclear factor (NF)-kappa B and NF-IL-6. (1996) (181)
- Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3 (2011) (179)
- The VP35 Protein of Ebola Virus Inhibits the Antiviral Effect Mediated by Double-Stranded RNA-Dependent Protein Kinase PKR (2006) (173)
- The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. (1996) (165)
- The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells (1996) (155)
- Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene (1997) (143)
- Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses (2012) (143)
- The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling. (1999) (140)
- Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ134.5 Protein (2005) (139)
- Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. (2005) (113)
- TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I–like receptor-mediated innate immune response (2013) (103)
- Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes (2011) (102)
- ICP34.5 Protein of Herpes Simplex Virus Facilitates the Initiation of Protein Translation by Bridging Eukaryotic Initiation Factor 2α (eIF2α) and Protein Phosphatase 1* (2011) (92)
- Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein. (2005) (90)
- Recognition of herpes simplex viruses: toll-like receptors and beyond. (2014) (89)
- Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome. (2015) (87)
- Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D (2017) (80)
- Inhibition of TANK Binding Kinase 1 by Herpes Simplex Virus 1 Facilitates Productive Infection (2011) (75)
- Enterovirus 71 3C Inhibits Cytokine Expression through Cleavage of the TAK1/TAB1/TAB2/TAB3 Complex (2014) (74)
- Signals That Dictate Nuclear, Nucleolar, and Cytoplasmic Shuttling of the γ134.5 Protein of Herpes Simplex Virus Type 1 (2002) (74)
- Synergistic activation of the human cytomegalovirus major immediate early promoter by prostaglandin E2 and cytokines. (1998) (64)
- A role for CCN3 (NOV) in calcium signalling (2002) (62)
- TRIM38 Negatively Regulates TLR3-Mediated IFN-β Signaling by Targeting TRIF for Degradation (2012) (60)
- Synthesis of prostaglandin H synthase-2 by human alveolar macrophages in response to lipopolysaccharide is inhibited by decreased cell oxidant tone. (1994) (59)
- The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. (2010) (55)
- Replication of Herpes Simplex Virus 1 Depends on the γ134.5 Functions That Facilitate Virus Response to Interferon and Egress in the Different Stages of Productive Infection (2004) (53)
- Val193 and Phe195 of the γ134.5 Protein of Herpes Simplex Virus 1 Are Required for Viral Resistance to Interferon-α/β (2001) (53)
- Enterovirus 68 3C Protease Cleaves TRIF To Attenuate Antiviral Responses Mediated by Toll-Like Receptor 3 (2014) (53)
- 3C Protease of Enterovirus D68 Inhibits Cellular Defense Mediated by Interferon Regulatory Factor 7 (2015) (50)
- Herpes Simplex Virus 1 γ134.5 Protein Inhibits STING Activation That Restricts Viral Replication (2018) (46)
- Dephosphorylation of eIF-2α Mediated by the γ134.5 Protein of Herpes Simplex Virus Type 1 Is Required for Viral Response to Interferon but Is Not Sufficient for Efficient Viral Replication (2003) (43)
- p32 Is a Novel Target for Viral Protein ICP34.5 of Herpes Simplex Virus Type 1 and Facilitates Viral Nuclear Egress* (2014) (42)
- Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the γ134.5 Protein That Facilitates Nuclear Egress (2016) (41)
- Cytomegalovirus modulates transcription factors necessary for the activation of the tumor necrosis factor-alpha promoter. (1997) (41)
- Silica increases tumor necrosis factor (TNF) production, in part, by upregulating the TNF promoter. (1994) (41)
- Enterovirus 3A Facilitates Viral Replication by Promoting Phosphatidylinositol 4-Kinase IIIβ–ACBD3 Interaction (2017) (40)
- The γ134.5 Protein of Herpes Simplex Virus 1 Is Required To Interfere with Dendritic Cell Maturation during Productive Infection (2009) (39)
- Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis (2001) (38)
- AlaArg Motif in the Carboxyl Terminus of the γ134.5 Protein of Herpes Simplex Virus Type 1 Is Required for the Formation of a High-Molecular-Weight Complex That Dephosphorylates eIF-2α (2001) (35)
- The Akt1 Isoform Is Required for Optimal IFN-β Transcription through Direct Phosphorylation of β-Catenin (2012) (33)
- A Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation through Protein Phosphatase 1 and IκB Kinase (2011) (32)
- Human herpesvirus-8 in northwestern China: epidemiology and characterization among blood donors (2010) (32)
- The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A (2017) (31)
- Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex (2018) (29)
- A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cells (2008) (26)
- Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy (2019) (25)
- Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication. (2003) (22)
- Dephosphorylation of eIF2α Mediated by the γ134.5 Protein of Herpes Simplex Virus 1 Facilitates Viral Neuroinvasion (2009) (19)
- Amino acid substitutions in the effector domain of the γ134.5 protein of herpes simplex virus 1 have differential effects on viral response to interferon-α (2003) (18)
- Val193 and Phe195 of the gamma 1 34.5 protein of herpes simplex virus 1 are required for viral resistance to interferon-alpha/beta. (2001) (18)
- The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein* (2015) (16)
- The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I (2021) (13)
- Herpes Simplex Virus 1 Suppresses the Function of Lung Dendritic Cells via Caveolin-1 (2015) (12)
- An Engineered Herpesvirus Activates Dendritic Cells and Induces Protective Immunity (2017) (12)
- Enterovirus 71 3 C Inhibits Cytokine Expression through Cleavage of the TAK 1 / TAB 1 / TAB 2 / TAB 3 Complex (2014) (12)
- Activation of NF-κB in CD8+ Dendritic Cells Ex Vivo by the γ134.5 Null Mutant Correlates with Immunity against Herpes Simplex Virus 1 (2011) (10)
- Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA (2007) (10)
- AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha. (2001) (9)
- Selective Editing of Herpes Simplex Virus 1 Enables Interferon Induction and Viral Replication That Destroy Malignant Cells (2018) (9)
- Crystal structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein (2019) (8)
- Characterization of the triplet repeats in the central domain of the gamma134.5 protein of herpes simplex virus 1. (2005) (8)
- Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor (2020) (6)
- Amino acid substitutions in the effector domain of the gamma(1)34.5 protein of herpes simplex virus 1 have differential effects on viral response to interferon-alpha. (2003) (5)
- Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23. (2021) (4)
- Oncolytic HSV: Underpinnings of Tumor Susceptibility (2021) (4)
- The effect of dimethyl sulfoxide on activation of the major immediate early promoter of human cytomegalovirus. (1998) (3)
- Comparative transcriptome analysis of normal and CD44-deleted mouse brain under chronic infection with Toxoplasma gondii. (2020) (2)
- Herpes simplex viruses and induction of interferon responses (2008) (2)
- Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2 (cid:2) Dephosphorylation by the (cid:3) 1 34.5 Protein (2005) (0)
- Establishment of proprotein convertase subtilisin/kexin type 9 nanovaccine and in vitro study on cellular uptake efficiency (2020) (0)
- 1679Interactions of the Herpes Simplex Virus γ34.5 Protein With Host Signaling Pathways Influence Central Nervous System Disease in Newborn Mice (2014) (0)
- SS10-5 HSVγ134.5 impairs TLR4 mediated inflammatory cytokine responses through dephosphorylation of IKK-β (2010) (0)
- HSV Replication: Triggering and Repressing STING Functionality (2023) (0)
- on Stimulator of IFN Genes Viral DNA through a Mechanism Dependent in Myeloid Cells Is Mediated by Cytoplasmic -Herpesviruses a Activation of Autophagy by (2011) (0)
- Dephosphorylation of eIF-2 (cid:2) Mediated by the (cid:3) 1 34.5 Protein of Herpes Simplex Virus Type 1 Is Required for Viral Response to Interferon but Is Not Sufficient for Efficient Viral Replication (2003) (0)
- , Phosphatase 1 ) and Protein α ( eIF 2 α Initiation Factor 2 Translation by Bridging Eukaryotic Facilitates the Initiation of Protein ICP 34 . 5 Protein of Herpes Simplex Virus Protein Synthesis and Degradation (2011) (0)
- This information is current as-Catenin β Phosphorylation of Transcription through Direct β IFN-The Akt 1 Isoform Is Required for Optimal (2012) (0)
- Regulation of T cell Activation By Herpes Simplex Virus 1 Protein Us3 (2016) (0)
- The (cid:2) 1 34.5 Protein of Herpes Simplex Virus 1 Is Required To Interfere with Dendritic Cell Maturation during Productive Infection (cid:1) (2009) (0)
- A Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation through Protein Phosphatase 1 and I (cid:1) B Kinase (cid:1) (2011) (0)
- Increased effi cacy of an interleukin-12- secreting herpes simplex virus in a syngeneic intracranial murine glioma model1 (2005) (0)
- Herpes simplex viruses and interferon responses (2012) (0)
- An Herpesvirus Virulence Factor Inhibits Dendritic Cell Activation Through 3 Protein Phosphatase 1 and I κ B Kinase 4 5 (2010) (0)
- Zhuo by Toll-Like Receptor 3 To Attenuate Antiviral Responses Mediated Enterovirus 68 3 C Protease Cleaves TRIF (2014) (0)
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Bin He is affiliated with the following schools:
