Björn Vennström
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Swedish biologist
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Björn Vennströmbiology Degrees
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Endocrinology
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Biology
Björn Vennström's Degrees
- PhD Biological Sciences Uppsala University
Why Is Björn Vennström Influential?
(Suggest an Edit or Addition)According to Wikipedia, Björn Vennström is a Swedish molecular biologist. He received his Ph.D. in 1978 at Uppsala University with a thesis on RNA and in 1993, was appointed Professor of Developmental Biology at the Karolinska Institute. He is also a professor of molecular biology at the same institution. He was elected a member of the Royal Swedish Academy of Sciences, was awarded the Göran Gustafsson Prize in 1991, has served on the Nobel Committee for Physiology or Medicine from 2001 to 2006, and is the Chairman of the Nobel Assembly.
Björn Vennström's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The c-erb-A protein is a high-affinity receptor for thyroid hormone (1986) (1234)
- Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor α1 (1998) (518)
- A thyroid hormone receptor that is required for the development of green cone photoreceptors (2001) (515)
- Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation. (1999) (443)
- Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product (1989) (351)
- Contrasting developmental and tissue‐specific expression of alpha and beta thyroid hormone receptor genes. (1990) (295)
- Functions of thyroid hormone receptors in mice. (2000) (287)
- Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus (1982) (262)
- Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes (1983) (242)
- Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism (2002) (217)
- Selective thyroid hormone receptor-β activation: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability (2003) (217)
- v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA (1990) (206)
- Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor alpha1 can be ameliorated by T3 treatment. (2005) (204)
- Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha. (2008) (193)
- Retardation of post‐natal development caused by a negatively acting thyroid hormone receptor α1 (2002) (181)
- Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription. (2002) (174)
- A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2 (1976) (169)
- Patterns of liver gene expression governed by TRbeta. (2002) (166)
- Depressed thermogenesis but competent brown adipose tissue recruitment in mice devoid of all hormone-binding thyroid hormone receptors. (2004) (159)
- International Union of Pharmacology. LIX. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Thyroid Hormone Receptors (2006) (157)
- Molecular cloning of the avian myelocytomatosis virus genome and recovery of infectious virus by transfection of chicken cells (1981) (157)
- Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells (1980) (155)
- Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes. (1991) (152)
- Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRα1) (2002) (151)
- Thyroid hormone receptors in chick retinal development: differential expression of mRNAs for alpha and N-terminal variant beta receptors. (1992) (142)
- Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice. (2002) (141)
- Thyroid hormone receptor beta1 acts as a potent suppressor of tumor invasiveness and metastasis. (2009) (140)
- Retardation of Cochlear Maturation and Impaired Hair Cell Function Caused by Deletion of All Known Thyroid Hormone Receptors (2001) (131)
- Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor α1 (2007) (130)
- Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. (2000) (130)
- Thyroid status during skeletal development determines adult bone structure and mineralization. (2007) (127)
- v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (Band 3) gene (1988) (125)
- v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation (1986) (124)
- Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing. (1998) (122)
- The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons. (2010) (115)
- Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor. (2000) (113)
- A major thyroid hormone response element in the third intron of the rat growth hormone gene. (1990) (113)
- Ablation of TRalpha2 and a concomitant overexpression of alpha1 yields a mixed hypo- and hyperthyroid phenotype in mice. (2001) (111)
- Lack of thyroid hormone receptor α1 is associated with selective alterations in behavior and hippocampal circuits (2003) (111)
- Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2. (1980) (110)
- Activation of protein kinase C or cAMP‐dependent protein kinase increases phosphorylation of the c‐erbA‐encoded thyroid hormone receptor and of the v‐erbA‐encoded protein. (1988) (108)
- Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts. (1988) (107)
- Cardiovascular phenotype and temperature control in mice lacking thyroid hormone receptor-β or both α1 and β. (1999) (98)
- Characterization of the hormone‐binding domain of the chicken c‐erbA/thyroid hormone receptor protein. (1988) (97)
- Phorbol ester-induced terminal differentiation is inhibited in human U-937 monoblastic cells expressing a v-myc oncogene. (1988) (96)
- RNA synthesis and processing in adenovirus-infected cells. (1975) (93)
- Identification and analysis of all components of a gel retardation assay by combination with immunoblotting. (1993) (91)
- Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1 (2013) (90)
- Locomotor Deficiencies and Aberrant Development of Subtype-Specific GABAergic Interneurons Caused by an Unliganded Thyroid Hormone Receptor α1 (2008) (89)
- Distinct Tissue-Specific Roles for Thyroid Hormone Receptors β and α1 in Regulation of Type 1 Deiodinase Expression (2001) (88)
- Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes. (1991) (85)
- Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs. (1992) (85)
- Effects of thyroid hormone receptor gene disruption on myosin isoform expression in mouse skeletal muscles. (2000) (83)
- Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions. (2013) (81)
- Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v‐erbA. (1994) (81)
- Evidence that decreased heart rate in thyroid hormone receptor-α1-deficient mice is an intrinsic defect. (1998) (80)
- Isolation and characterization of multiple human genes homologous to the oncogenes of avian erythroblastosis virus. (1983) (72)
- Thyroid hormone alters the DNA binding properties of chicken thyroid hormone receptors α and β (1992) (69)
- Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter. (1985) (68)
- A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes. (1987) (66)
- Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms. (2004) (65)
- Ligand-dependent and -independent transactivation by thyroid hormone receptor beta 2 is determined by the structure of the hormone response element (1995) (64)
- Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v‐myc oncogene. (1984) (64)
- Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone receptors. (2005) (60)
- Cardiovascular phenotype and temperature control in mice lacking thyroid hormone receptor-beta or both alpha1 and beta. (1999) (57)
- Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene. (2001) (54)
- Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary. (2005) (52)
- Multiple Phenotypes in Adult Mice following Inactivation of the Coxsackievirus and Adenovirus Receptor (Car) Gene (2011) (50)
- TRs have common and isoform-specific functions in regulation of the cardiac myosin heavy chain genes. (2001) (49)
- Adaptations of the autonomous nervous system controlling heart rate are impaired by a mutant thyroid hormone receptor-alpha1. (2010) (48)
- Increased depressive behaviour in mice harboring the mutant thyroid hormone receptor alpha 1 (2010) (46)
- Serum copper as a novel biomarker for resistance to thyroid hormone. (2012) (46)
- Thyroid Hormones Regulate Selenoprotein Expression and Selenium Status in Mice (2010) (45)
- Transcriptional repression of band 3 and CAII in v‐erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype. (1992) (44)
- Evidence that decreased heart rate in thyroid hormone receptor-alpha1-deficient mice is an intrinsic defect. (1998) (43)
- Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism. (2009) (42)
- Two different mRNAs are transcribed from a single genomic locus encoding the chicken erythrocyte anion transport proteins (band 3) (1988) (42)
- GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/-beta-/- mice. (2001) (42)
- Severe psychomotor and metabolic damages caused by a mutant thyroid hormone receptor alpha 1 in mice: can patients with a similar mutation be found and treated? (2008) (42)
- Expression of peptides and other neurochemical markers in hypothalamus and olfactory bulb of mice devoid of all known thyroid hormone receptors (2000) (41)
- Aberrant expression of myosin isoforms in skeletal muscles from mice lacking the rev-erbAalpha orphan receptor gene. (2005) (40)
- The transforming activity of the chicken c-myc gene can be potentiated by mutations. (1987) (40)
- The E5 gene of bovine papillomavirus type 1 is sufficient for complete oncogenic transformation of mouse fibroblasts. (1988) (39)
- Distinct tissue-specific roles for thyroid hormone receptors beta and alpha1 in regulation of type 1 deiodinase expression. (2001) (36)
- Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts (1986) (34)
- Impaired Ca2+ handling and contraction in cardiomyocytes from mice with a dominant negative thyroid hormone receptor alpha1. (2005) (30)
- The sound of silence (1995) (29)
- Transactivation by the thyroid hormone receptor is dependent on the spacer sequence in hormone response elements containing directly repeated half-sites. (1996) (29)
- Isometric force and endurance in soleus muscle of thyroid hormone receptor-α1- or -β-deficient mice (2000) (28)
- A point mutation in the DNA binding domain of the v-myb oncogene of E26 virus confers temperature sensitivity for transformation of myelomonocytic cells. (1988) (28)
- Audiogenic seizure susceptibility in thyroid hormone receptor β-deficient mice (2001) (28)
- Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver. (2003) (27)
- Defective v-erbB genes can be complemented by v-erbA in erythroblast and fibroblast transformation. (1987) (27)
- Chicken thyroid hormone receptor α requires the N‐terminal amino acids for exclusive nuclear localization (1997) (25)
- The adenovirus E1A protein is a potent coactivator for thyroid hormone receptors. (1999) (25)
- The v-erb A oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors. (1990) (23)
- Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repression. (1990) (23)
- 3‐Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo (2015) (23)
- A mutant thyroid hormone receptor alpha1 alters hippocampal circuitry and reduces seizure susceptibility in mice (2010) (21)
- Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice. (2016) (20)
- Identification of Reverb as a physiological repressor of apoC-III gene transcription 1 (2002) (19)
- Physiological consequences of the TRα1 aporeceptor state (2010) (19)
- The SMAGE gene family is expressed in post-meiotic spermatids during mouse germ cell differentiation (2004) (19)
- Fidelity of adenovirus RNA transcription in isolated HeLa cell nuclei (1977) (17)
- Chromosomal assignment of five cancer-associated rat genes: two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene. (1991) (16)
- Accelerated Inactivation of Voltage‐Dependent K+ Outward Current in Cardiomyocytes from Thyroid Hormone Receptor α1‐Deficient Mice (2002) (16)
- The chicken c-erbA alpha-product induces expression of thyroid hormone-responsive genes in 3,5,3'-triiodothyronine receptor-deficient rat hepatoma cells. (1990) (16)
- Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area (2018) (16)
- Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice. (2000) (14)
- Identification of thyroid hormone response elements in vivo using mice expressing a tagged thyroid hormone receptor α1 (2013) (14)
- Thyroid hormone receptor α can control action potential duration in mouse ventricular myocytes through the KCNE1 ion channel subunit (2010) (14)
- Audiogenic seizure susceptibility in thyroid hormone receptor beta-deficient mice. (2001) (14)
- Ablation of TR (cid:1) 2 and a Concomitant Overexpression of (cid:1) 1 Yields a Mixed Hypo- and Hyperthyroid Phenotype in Mice (2001) (12)
- Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells. (2010) (12)
- The Thyroid Hormone Receptor α1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neuronal Cells (2010) (12)
- Thyroid hormone alters the DNA binding properties of chicken thyroid hormone receptors alpha and beta. (1992) (11)
- A selectable temperature-sensitive v-src Moloney retrovirus. (1988) (11)
- Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities. (1994) (10)
- Avian acute leukemia virus OK 10: analysis of its myc oncogene by molecular cloning (1983) (9)
- Versatile avian retrovirus vectors. (1993) (8)
- Identification of DNA binding sites for the v-erbA oncoprotein, the viral homolog to thyroid hormone receptor alpha (1998) (6)
- The oncoprotein P75gag-v-erbA represses thyroid hormone induced transcription only via response elements containing palindromic half-sites. (1996) (6)
- Transcription and Processing of Adenovirus RNA in Productive Infection (1973) (6)
- Detection and temporal appearance of multiple copies of c-erb-B2 genes in advanced mammary carcinoma using fine needle biopsies and the polymerase chain reaction (2005) (5)
- Zonal expression of the thyroid hormone receptor (cid:1) isoforms in rodent liver (2003) (5)
- A choice between transcriptional enhancement and repression by the v-erbA oncoprotein governed by one nucleotide in a thyroid hormone responsive half site (2000) (5)
- Effective generation of transgenic mice by Bovine papillomavirus type 1 based self-replicating plasmid that is maintained as extrachromosomal genetic element in three generations of animals. (2003) (4)
- Requirements for repression of retinoid X receptor by the oncoprotein P75gag-v-erbA and the thyroid hormone receptors. (1998) (4)
- Altered expression after expansion of a v-erbA transgene in transgenic mice (1995) (4)
- The mutated, myeloid cell-specific growth factor receptor v-fms transforms avian erythroid but not myeloid cells. (1989) (4)
- Anchorage-independent growth of v-myc-transformed Balb/c 3T3 cells is promoted by platelet-derived growth factor or co-transformation by other oncogenes. (1987) (4)
- GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor (cid:1) 1 − / − (cid:2) − / − mice (2001) (3)
- Requirement for Thyroid Hormone Receptor (cid:1) in T 3 Regulation of Cholesterol Metabolism in Mice (2002) (3)
- Cooperativity of viral oncogenes in avian leukaemia. (1988) (2)
- Thyroid Hormone Receptors (2010) (2)
- Functions of the erbA and erbB Oncogenes in Avian Erythroblatosis (1989) (2)
- Replication of the bovine papillomavirus type 1 genome; antisense transcripts prevent episomal replication. (1986) (2)
- Thyroid hormone drives the expression of mouse carbonic anhydrase Car4 in kidney, lung and brain (2015) (2)
- GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor 1−/− −/− mice (2001) (1)
- Mutational Analysis of v-erbB Oncogene Function (1986) (1)
- Expression of myosin isoforms in skeletal muscles in mice lacking the rev-erb Alpha orphan receptor (2004) (1)
- The Thyroid Hormone Receptor/c-erbA Protein and its Viral Homologue P75gag-v-erbA (1989) (1)
- Disruption of intramembranous and endochondral bone development in TRalpha 2 null mice (2005) (0)
- Elucidating the actions of 3-Iodothyroacetic acid in thermoregulation and cardiovascular function (2014) (0)
- Adult mice harbouring a dominant negative R384C mutation of TRalpha1 have a marked increase in trabecular bone and micro-mineralisation density (2006) (0)
- DNA Binding Properties of the Thyroid Hormone Receptor/c-erbA Protein and Its Viral Homologue P75gag-v-erbA (1990) (0)
- Transcription of adenovirus RNA (1978) (0)
- Biological effects of the v-erbA oncogene in transformation of avian erythroid cells. (1987) (0)
- Phenotype of mice harboring a thyroid hormone receptor alpha 1 gene with transdominant negative properties (2001) (0)
- British Thyroid Association Pitt Rivers Lecture (2006) (0)
- Transformation Capacities of a Murine Retrovirus Encoding an Avian myc Oncogene (1984) (0)
- The decision of the Karolinska Institute following an independent investigation of the research carried out by Associate Professor Ulf Lönn. (1998) (0)
- Contrasting developmental andtissue-specific expression ofaeand thyroid hormonereceptor genes (1990) (0)
- [Intensive studies on Drosophila lead to Nobel prize. A few genes direct the development of parts of the body]. (1995) (0)
- [The 1995 Nobel Prize in medicine or physiology--awarded Edward B. Lewis, Christiane Nusslein-Volhard and Eric Wieschaus]. (1995) (0)
- Neurological abnormalities in mice with a dominant negative thyroid hormone alpha 1 (2006) (0)
- Chicken Epidermal GrowthFactor (EGF)Receptor: cDNACloning, Expression inMouseCells, andDifferential Binding ofEGFand Transforming GrowthFactor Alpha (1988) (0)
- Transcription and processing of viral messenger RNA in mammalian cells. (1973) (0)
- Rous-Associated Virus1-Induced Erythroleukemic Cells Exhibit a WeaklyTransformed Phenotype InVitro andRelease c-erbB-Containing (1986) (0)
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