Bonnie Sloane | Academic Influence

Bonnie Sloane's AcademicInfluence.com Rankings

Bonnie Sloane

Medical

#2569

World Rank

#2998

Historical Rank

Pharmacology

#270

World Rank

#318

Historical Rank

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Medical

Bonnie Sloane's Degrees

PhD Pharmacology University of California, San Francisco
Bachelors Biology Stanford University

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Why Is Bonnie Sloane Influential?

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According to Wikipedia, Bonnie Fiedorek Sloane is a distinguished professor at Wayne State University known for her research on cancer. In 2021 she was elected a fellow of the American Association for the Advancement of Science.

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Bonnie Sloane's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cysteine cathepsins: multifunctional enzymes in cancer (2006) (1168)
Acidity generated by the tumor microenvironment drives local invasion. (2013) (917)
Unraveling the role of proteases in cancer. (2000) (580)
Bicarbonate increases tumor pH and inhibits spontaneous metastases. (2009) (533)
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues. (1992) (425)
Lysosomal cathepsin B: correlation with metastatic potential. (1981) (384)
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. (1994) (367)
Dynamic imaging of protease activity with fluorescently quenched activity-based probes (2005) (305)
Cysteine cathepsins in human cancer (2004) (282)
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. (1994) (254)
Cathepsin B: Multiple roles in cancer (2014) (252)
Proteases, extracellular matrix, and cancer: a workshop of the path B study section. (2004) (234)
Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival. (1994) (229)
Cathepsin B: association with plasma membrane in metastatic tumors. (1986) (225)
Pericellular cathepsin B and malignant progression (2003) (224)
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. (2002) (221)
Cathepsin B expression and localization in glioma progression and invasion. (1994) (221)
Cathepsin B activity in B16 melanoma cells: a possible marker for metastatic potential. (1982) (220)
Cathepsin B and cystatins: evidence for a role in cancer progression. (1990) (214)
Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. (2012) (205)
Cathepsin b: a potential prognostic marker for inflammatory breast cancer (2011) (200)
Human Procathepsin B Interacts with the Annexin II Tetramer on the Surface of Tumor Cells* (2000) (198)
Cathepsin B and its role(s) in cancer progression. (2003) (197)
Cathepsin B and human tumor progression. (1998) (192)
Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene. (1994) (188)
Cell surface complex of cathepsin B/annexin II tetramer in malignant progression. (2000) (186)
Cathepsin B inhibition limits bone metastasis in breast cancer. (2012) (174)
Morphological study of the interaction of intravascular tumor cells with endothelial cells and subendothelial matrix. (1988) (168)
Prostacyclin and thromboxanes. Implications for their role in tumor cell metastasis. (1983) (157)
Arrest and extravasation of B16 amelanotic melanoma in murine lungs. A light and electron microscopic study. (1985) (156)
Imaging proteolysis by living human breast cancer cells. (2000) (155)
Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment. (2005) (151)
Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1. (2005) (150)
Molecular Regulation of Human Cathepsin B: Implication in Pathologies (2003) (144)
Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass. (1999) (140)
Expression of cathepsins B and S in the progression of prostate carcinoma (2001) (133)
Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis. (1995) (129)
Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells (2005) (123)
Human tumour cathepsin B. Comparison with normal liver cathepsin B. (1992) (123)
Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ. (2009) (117)
A lipoxygenase metabolite, 12-(S)-HETE, stimulates protein kinase C-mediated release of cathepsin B from malignant cells. (1994) (113)
Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation. (2009) (111)
Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts. (2008) (107)
Mammalian cysteine protease inhibitors: biochemical properties and possible roles in tumor progression. (1995) (106)
Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue. (2005) (106)
Molecular regulation, membrane association and secretion of tumor cathepsin B (1999) (101)
Cathepsin B expression in human tumors. (1996) (100)
Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion (2011) (100)
Cathepsin B and glioma invasion (1999) (99)
Cathepsin B and its endogenous inhibitors: the role in tumor malignancy (1990) (97)
Degradation of Extracellular Matrix Protein Tenascin-C by Cathepsin B: An Interaction Involved in the Progression of Gliomas (2002) (96)
Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression (2014) (92)
Tumor progression and angiogenesis: cathepsin B & Co. (1996) (92)
Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. (2013) (91)
p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer. (2008) (90)
Immunohistochemical localization of cathepsin B in neoplastic human prostate (1995) (88)
Phorbol Ester Activation of a Proteolytic Cascade Capable of Activating Latent Transforming Growth Factor-β (2002) (87)
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer. (2006) (86)
Immunohistochemical analysis of cathepsins D, B, and L in human breast cancer. (1994) (86)
Tumor cell-platelet aggregation: induced by cathepsin B-like proteinase and inhibited by prostacyclin. (1982) (85)
Membrane-associated cathepsin L: a role in metastasis of melanomas. (1989) (84)
Transcription of human cathepsin B is mediated by Sp1 and Ets family factors in glioma. (2000) (82)
Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells. (2003) (82)
Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells (2004) (81)
Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties. (2014) (80)
Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration (2015) (80)
Identification of two new exons and multiple transcription start points in the 5'-untranslated region of the human cathepsin-B-encoding gene. (1995) (79)
Cathepsin B: multiple enzyme forms from a single gene and their relation to cancer. (1996) (78)
Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. (2009) (77)
Interaction of Human Breast Fibroblasts with Collagen I Increases Secretion of Procathepsin B* (2002) (77)
Properties of a plasma membrane-associated cathepsin B-like cysteine proteinase in metastatic B16 melanoma variants. (1987) (76)
Plasma membrane-associated cysteine proteinases in human and animal tumors. (1987) (76)
Role of the coagulation system in tumor-cell-induced platelet aggregation and metastasis. (1988) (76)
Analysis of a Truncated Form of Cathepsin H in Human Prostate Tumor Cells* (2002) (74)
Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer. (2005) (74)
Functional imaging of tumor proteolysis. (2006) (74)
Cathepsin C is a tissue-specific regulator of squamous carcinogenesis (2013) (72)
Invasiveness of Transformed Human Breast Epithelial Cell Lines Is Related to Cathepsin B and Inhibited by Cysteine Proteinase Inhibitors (2003) (72)
Chapter 12 – Regulation of Lysosomal Endopeptidases in Malignant Neoplasia (1994) (68)
Cysteine proteinases and metastasis (2004) (68)
Inhibitory properties of low molecular mass cysteine proteinase inhibitors from human sarcoma. (1989) (65)
Chiral porphyrazine near-IR optical imaging agent exhibiting preferential tumor accumulation (2009) (65)
Localization of a biotinylated cathepsin B oligonucleotide probe in human prostate including invasive cells and invasive edges by in situ hybridization (1993) (64)
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. (2004) (63)
Visualizing Protease Activity in Living Cells: From Two Dimensions to Four Dimensions (2008) (62)
Interleukin-6 Increases Expression and Secretion of Cathepsin B by Breast Tumor-Associated Monocytes (2010) (61)
Imaging and quantifying the dynamics of tumor-associated proteolysis (2008) (60)
Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis. (2003) (59)
Cell-surface cathepsin B: understanding its functional significance. (2003) (59)
Differential Localization of Cysteine Protease Inhibitors and a Target Cysteine Protease, Cathepsin B, by Immuno-Confocal Microscopy (1998) (58)
Degradation of laminin by human tumor cathepsin B (1989) (58)
Inhibition by dihydropyridine class calcium channel blockers of tumor cell-platelet-endothelial cell interactions in vitro and metastasis in vivo. (1985) (58)
Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors. (1990) (57)
Cathepsin B in angiogenesis of human prostate: An immunohistochemical and immunoelectron microscopic analysis (1995) (57)
Cystatin M (2004) (57)
Fluorescent microplate assay for cancer cell-associated cathepsin B. (2000) (57)
Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells. (2008) (57)
Gene trapping in differentiating cell lines: regulation of the lysosomal protease cathepsin B in skeletal myoblast growth and fusion (1996) (56)
Microglial Cathepsin B: An Immunological Examination of Cellular and Secreted Species (1995) (55)
Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene. (1994) (54)
Electron probe analysis of cultured vascular smooth muscle (1980) (53)
The cysteine protease cathepsin B in cancer (1996) (53)
Phorbol ester activation of a proteolytic cascade capable of activating latent TGF-β: A process initiated by the exocytosis of cathepsin B (2002) (52)
Enhanced levels of cathepsin B mRNA in murine tumors (1989) (51)
Antithrombogenic effects of calcium channel blockers: synergism with prostacyclin and thromboxane synthase inhibitors. (1984) (50)
Human monocytes augment invasiveness and proteolytic activity of inflammatory breast cancer (2008) (50)
Clinicopathologic significance of cathepsin B immunostaining in transitional neoplasia. (1994) (49)
Role of platelet membrane in enhancement of tumor cell adhesion to endothelial cell extracellular matrix. (1987) (49)
Plasma membrane association of cathepsin B in human prostate cancer: Biochemical and immunogold electron microscopic analysis (2001) (48)
Inhibition of Human Tumor Cell Induced Platelet Aggregation by Antibodies to Platelet Glycoproteins lb and llb/llla (1987) (48)
Oncogenic c-Ki-ras but Not Oncogenic c-Ha-ras Up-regulates CEA Expression and Disrupts Basolateral Polarity in Colon Epithelial Cells* (1997) (47)
The role of platelet cyclooxygenase and lipoxygenase pathways in tumor cell induced platelet aggregation. (1987) (47)
Rac1-induced endocytosis is associated with intracellular proteolysis during migration through a three-dimensional matrix. (2000) (45)
Acidosis and proteolysis in the tumor microenvironment (2019) (44)
MAME models for 4D live-cell imaging of tumor: microenvironment interactions that impact malignant progression. (2012) (44)
Determination of Cathepsin B Expression May Offer Additional Prognostic Information for Ovarian Cancer Patients (2002) (44)
Myoepithelial cell‐specific expression of stefin A as a suppressor of early breast cancer invasion (2017) (43)
Purification and characterization of platelet aggregating activity from tumor cells: copurification with procoagulant activity. (1985) (43)
RNA-Seq of Human Breast Ductal Carcinoma In Situ Models Reveals Aldehyde Dehydrogenase Isoform 5A1 as a Novel Potential Target (2012) (42)
Suicidal tumor proteases (1996) (42)
Next-generation sequencing: a powerful tool for the discovery of molecular markers in breast ductal carcinoma in situ (2013) (42)
Metabotropic Glutamate Receptor-1 Contributes to Progression in Triple Negative Breast Cancer (2014) (41)
A possible role for cysteine proteinase and its inhibitors in motility of malignant melanoma and other tumour cells (1992) (39)
Imaging Proteolysis by Living Human Glioma Cells (2001) (39)
Cathepsin B and D are localized at the surface of human breast cancer cells (2008) (39)
Tumor cell-platelet interactions in vitro and their relationship to in vivo arrest of hematogenously circulating tumor cells (2004) (39)
Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models (2015) (38)
Tumor Cell Membrane Cathepsin B (1998) (37)
Cysteine proteases and tumor progression (1995) (36)
Ratio of cathepsin B to stefin A identifies heterogeneity within Gleason histologic scores for human prostate cancer (2001) (35)
Cisplatin and nifedipine: synergistic cytotoxicity against murine solid tumors and their metastases. (1986) (35)
Cathepsin B localizes to plasma membrane caveolae of differentiating myoblasts and is secreted in an active form at physiological pH (2006) (34)
Inhibition of tumor cell induced platelet aggregation by prostacyclin and carbacyclin: an ultrastructural study. (1987) (34)
Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells. (1998) (33)
Expression of cathepsins B, D and L in mouse corneas infected with Pseudomonas aeruginosa. (2001) (33)
Aborted Autophagy and Nonapoptotic Death Induced by Farnesyl Transferase Inhibitor and Lovastatin (2011) (32)
A new in vitro model for investigation of tumor cell-platelet-endothelial cell interactions and concomitant eicosanoid biosynthesis. (1987) (31)
Inhibition by prostacyclin of the tumor cell-induced platelet release reaction and platelet aggregation. (1987) (31)
Differentiating agents regulate cathepsin B gene expression in HL‐60 cells (1999) (31)
Cathepsin B contributes to Na+ hyperabsorption in cystic fibrosis airway epithelial cultures (2014) (31)
Functional Live-Cell Imaging Demonstrates that β1-Integrin Promotes Type IV Collagen Degradation by Breast and Prostate Cancer Cells (2008) (31)
Cathepsin K in the bone microenvironment: link between obesity and prostate cancer? (2007) (30)
Observing proteases in living cells. (2000) (29)
Cathepsin B-like activity in viable tumor cells isolated from rodent tumors. (1985) (29)
On how mammary gland reprogramming metalloproteinases couple form with function. (2012) (29)
Role for cathepsin B and cystatins in tumor growth and progression. (1990) (29)
The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes (2013) (28)
Mechanisms of Cancer Metastasis (1986) (28)
Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironment. (2012) (28)
Platelet enhancement of tumor cell adhesion to subendothelial matrix: role of platelet cytoskeleton and platelet membrane. (1987) (28)
Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins (2012) (27)
Cathepsin B protein levels in endometrial cancer: Potential value as a tumour biomarker. (2009) (27)
Cathepsins D and B in breast cancer. (1996) (27)
In Vitro Models for Studying Invasive Transitions of Ductal Carcinoma In Situ (2018) (27)
The Cancer Degradome (2009) (27)
Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ (2017) (26)
Role of prostacyclin as a natural deterrent to hematogenous tumor metastasis. (1983) (26)
Hemostatic Mechanisms and Metastasis (2011) (26)
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer (2012) (26)
The malignant phenotype and cysteine proteinases. (1991) (25)
Calcium Channel Blockers: Potential Antimetastatic Agents (1983) (25)
Transcription of Cathepsin B in Glioma Cells: Regulation by an E-Box Adjacent to the Transcription Initiation Site (2003) (25)
Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function (2007) (24)
Codistribution of procathepsin B and mature cathepsin B forms in human prostate tumors detected by confocal and immunofluorescence microscopy (1998) (24)
Vascular smooth muscle mitochondria: magnesium content and transport. (1978) (23)
Malignant transformation alters intracellular trafficking of lysosomal cathepsin D in human breast epithelial cells (2008) (23)
Functional Imaging of Proteolysis: Stromal and Inflammatory Cells Increase Tumor Proteolysis (2003) (22)
Deficiency in metabolic regulators PPARγ and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. (2013) (22)
Evidence for the involvement of cathepsin B in skeletal myoblast differentiation (2002) (22)
Mapping of the gene for human cysteine proteinase inhibitor stefin A, STF1, to chromosome 3cen-q21. (1991) (21)
The relationship of cathepsin B and stefin A mRNA localization identifies a potentially aggressive variant of human prostate cancer within a Gleason histologic score. (1999) (21)
Hu/Mu ProtIn Oligonucleotide Microarray: Dual-Species Array for Profiling Protease and Protease Inhibitor Gene Expression in Tumors and Their Microenvironment (2007) (20)
Cathepsin B: Basis Sequence: Mouse. (2011) (20)
Cysteine endopeptidases and their inhibitors in malignant progression of rat embryo fibroblasts. (1992) (19)
A review of prostaglandins and the treatment of tumor metastasis. (1983) (19)
Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts (Cancer Research (2008) 68, (9147-9156)) (2009) (19)
Many Roles of CCL20: Emphasis on Breast Cancer. (2014) (19)
Expression of functional recombinant human procathepsin B in mammalian cells. (1996) (18)
3D/4D functional imaging of tumor-associated proteolysis: impact of microenvironment. (2012) (18)
Invasion of ras-Transformed Breast Epithelial Cells Depends on the Proteolytic Activity of Cysteine and Aspartic Proteinases (2001) (18)
Imaging Sites of Inhibition of Proteolysis in Pathomimetic Human Breast Cancer Cultures by Light-Activated Ruthenium Compound (2015) (18)
Lysosomal composition in cultured vascular smooth muscle cells: electron probe analysis. (1979) (17)
11 Alterations in Processing and Trafficking of Cathepsin B during Malignant Progression (1994) (17)
Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-β1-signaling and upregulation of cathepsin B (2007) (17)
Isolation of a novel USF2 isoform: repressor of cathepsin B expression. (2004) (17)
Exon 2 of human cathepsin B derives from an Alu element (1997) (17)
Capturing and Characterizing Immune Cells from Breast Tumor Microenvironment: An Innovative Surgical Approach (2010) (17)
Proteases in Cancer: Significance for Invasion and Metastasis (2013) (16)
Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation1 (2018) (16)
Cathepsin L splice variants in human breast cell lines (2006) (16)
Platelet-Tumor Cell Interactions as a Target for Antimetastatic Therapy (1986) (15)
Involvement of a cathepsin B-like cysteine proteinase in platelet aggregation induced by tumor cells and their shed membrane vesicles (1983) (15)
Tumor cathepsin B and its endogenous inhibitors in metastasis. (1988) (15)
Cooxidation of 13-cis-retinoic acid by prostaglandin H synthase. (1984) (15)
Imaging Proteolysis by Living Human Glioma Cells (2001) (15)
High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells. (2006) (14)
Bacterial expression of human cysteine proteinase inhibitor stefin A (1989) (14)
A flexible Ag/AgCl micro reference electrode based on a parylene tube structure. (2017) (12)
Cathepsin B on invasion and metastasis of gastric carcinoma. (1998) (12)
Calcium Channel Blockers: Inhibitors of Tumor Cell-Platelet-Endothelial Cell Interactions (1984) (12)
Effect of ovarian hormones on lysosomal acid hydrolase activities in rat myometrium. (1977) (12)
Inhibition of tumor cell-platelet interactions and tumor metastasis by the calcium channel blocker, nimodipine (2004) (12)
Prostacyclin/Thromboxanes and Tumor Cell Metastasis (1984) (11)
A membrane‐associated cysteine protease inhibitor from murine hepatoma (1992) (11)
I2 imaging: cancer biology and the tumor microenvironment. (2006) (11)
Effects of 12-Hydroxyeicosatetraenoic Acid on Release of Cathepsin B and Cysteine Proteinase Inhibitors from Malignant Melanoma Cells (1991) (10)
Photodynamic therapy as an effective therapeutic approach in MAME models of inflammatory breast cancer (2015) (10)
Selective inhibition of cathepsin B with cell-permeable CA074Me negatively affects L6 rat myoblast differentiation. (2002) (10)
PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms (2012) (10)
Evidence That E-Box Promoter Elements and MyoD Transcription Factors Play a Role in the Induction of Cathepsin B Gene Expression during Human Myoblast Differentiation (2002) (9)
Lysosomal apparatus in uterine muscle: effects of estrogen and of ovariectomy. (1980) (9)
Tumor cysteine proteinases and their inhibitors (1986) (8)
Cathepsin B-like cysteine proteinases and tumor metastasis (1984) (8)
Comprar The Cancer Degradome · Proteases and Cancer Biology | Edwards, Dylan | 9780387690568 | Springer (2009) (8)
Loss of caspase-8 in tumor cells: mechanism to overcome integrin-mediated death? (2006) (8)
Live-Cell Imaging of Protease Activity: Assays to Screen Therapeutic Approaches. (2017) (7)
The role of platelets in metastasis. (1987) (7)
Analysis of Platelet, Tumor Cell and Endothelial Cell Interactions in Vivo and in Vitro (1987) (7)
Prostacyclin, thromboxanes, and hematogenous metastasis. (1983) (7)
Fluorescent Imaging of Tumors (2007) (7)
Spatio-temporal modeling and live-cell imaging of proteolysis in the 4D microenvironment of breast cancer (2019) (6)
Possible strategies for antimetastastic therapy. (1986) (6)
Tumor Cysteine Proteinases, Platelet Aggregation and Metastasis (1984) (6)
Cathepsin B-Like Cysteine Proteinases and Metastasis (1986) (6)
The Effects of Eicosanoid Inhibitors on Tumor Cell Arachidonic Acid (and Metabolite) Uptake, Release and Metabolism (1987) (6)
Breast Cancer: Proteolysis and Migration. (2019) (6)
Effect of Estrogen on Lysosomal Enzyme Activities in Rat Heart (1984) (5)
Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodies (2015) (5)
Clinicopathologic Significance of Cathepsin B and Urokinase-type Plasminogen Activator Immunostaining in Colorectal Adenocarcinoma (1994) (5)
Molecular mechanisms of progression and metastasis of human tumors: a pathology B study section workshop. Working Report from the Division of Research Grants, NIH. (1994) (4)
Proteolytic Enzymes and Arachidonic Acid Metabolites (1985) (4)
Pathomimetic cancer avatars for live-cell imaging of protease activity. (2016) (4)
Cathepsin B: A proteinase linked to metastasis (1985) (4)
[7] Smooth muscle mitochondria (1979) (3)
Tumor cell-platelet-endothelial cell interactions and prostaglandin metabolism. (1987) (3)
Inhibitors of Papain-Like Cysteine Peptidases in Cancer (2000) (3)
Functional expression of recombinant human stefin A in mammalian and bacterial cells. (2007) (3)
Images of Cleavage: Tumor Proteases in Action (2008) (2)
Microarrays for protease detection in tissues and cells. (2009) (2)
Activation of a cathepsin B-like latent enzyme from cultures of murine B16 amelanotic melanoma (1984) (2)
Modeling Breast Cancer Progression in 4-D (2013) (2)
Roles of Pericellular Proteases in Tumor Angiogenesis: Therapeutic Implications (2018) (2)
Role of Eicosanoids in Tumor Cell-Platelet-Endothelial Cell Interactions (1987) (1)
MITOCHONDRIAL CALCIUM CONTENT IN VASCULAR SMOOTH MUSCLE (1979) (1)
Abstract #3186: Capturing cells migrating from breast tumor microenvironment: Innovative surgical approach (2009) (1)
Breast Cancer Cystatin M : A Novel Candidate Tumor Suppressor Gene for Updated (2004) (1)
Abstract B65: Live-cell imaging of 3D/4D parallel co-cultures of breast carcinoma cells and breast fibroblasts in tissue architecture and microenvironment engineering (TAME) chambers (2016) (1)
Monocytes/macrophages and natural killer cells characterize the tumor microenvironment of inflammatory breast cancer in Egyptian patients. (2009) (1)
Anti-tumor and immune modulating activity of T cell induced tumor-targeting effectors (TITE) (2020) (1)
PURIFICATION AND CHARACTERIZATION OF TWO PROCOAGULANTS FROM WALKER 256 CARCINOSARCOMA TUMORS, (1987) (1)
Abstract 2467: Acidic pericellular pH increases contribution of cathepsin B to invasiveness of a human breast carcinoma cell line (2012) (1)
Abstract B19: MET and IL6 signaling in triple-negative breast cancer (2016) (1)
Increased efficacy of photodynamic therapy via sequential targeting (2014) (1)
Screening of gastric cancer cell sublines using the adhesion method (2001) (1)
CYCLOOXYGENASE AND LIPOXYGENASE PRODUCTS SYNERGISTICALLY MODULATE TUMOR CELL INDUCED PLATELET AGGREGATION (1987) (0)
Abstract 2131: Paracrine cytokine pathways mediate metastasis of breast cancer to lymphatics (2018) (0)
Abstract B14: Sprouty4 regulates the transition to invasive breast ductal carcinoma through ERK/MAPK signaling (2018) (0)
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer (2012) (0)
The Hu/Mu ProtIn Chip: A Custom Dual-Species Oligonucleotide Microarray for Profiling Degradome Gene Expression in Tumors and Their Microenvironment (2008) (0)
Abstract 3150: Exploring the role of Rap1Gap in the progression from DCIS to invasive breast carcinoma (2014) (0)
Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy (2005) (0)
Abstract 430: MCP-1/CCL2 and IL-8 regulate proteolytic activity of triple negative inflammatory breast cancer via cathepsin B, ERK1/2, JAK1 and Src signaling pathways (2015) (0)
Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma (2021) (0)
Cathepsins B and K: Role in Metastasis of Human Prostate Cancer to Human Bone in an In Vivo SCID-hu Mouse Model (2001) (0)
ROLE OF PLATELET GLYCOPROTEINS lb AND llb/llla IN TUMOR CELL INDUCED PLATELET AGGREGATION AND TUMOR CELL ADHESION TO EXTRACELLULAR MATRIX. I. Grossi (1987) (0)
Hormonal alteration of lysosomal acid hydrolase activity in uterine muscle (1975) (0)
PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms (2012) (0)
Abstract 4560: Induced Sprouty4 expression in breast invasive ductal carcinoma cells downregulates ERK/MAPK activity and restores an epithelial-like phenotype (2016) (0)
Acidosis and proteolysis in the tumor microenvironment (2019) (0)
ID: 265 Tumor Microenvironment and Proteolysis (2006) (0)
Matrix Turnover – Mechanisms and Common Denominators: A Joint British Society for Matrix Biology/Biochemical Society Focused Meeting (2007) (0)
Optical imaging of tumor progression in living systems (2006) (0)
Cathepsinb: Regulation of expression and localization at sites of cell/matrk contact (1997) (0)
Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ (2017) (0)
Pathomimetic Avatars for Live‐Cell Imaging of Tumor Proteolysis and Drug Screening (2016) (0)
Cell-surface proteases in cancer (1999) (0)
Mechanisms of Cancer Metastasis: Potential Therapeutic Implications (2011) (0)
Isolated Membranes and Organelles from Vascular Smooth Muscle (2011) (0)
Modeling Tumor: Lymphatic Interactions in Lymphatic Metastasis of Triple Negative Breast Cancer (2021) (0)
Inhibition of lipoxygenase-mediated lysosomal cathepsin b release from tumor cells by nafazatrom. Abstr. (1982) (0)
Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration (2015) (0)
4D MAME Models for Live-Cell Imaging of Interactions Between Breast Tumor Cells and Their Microenvironment (2011) (0)
Session 8: Imaging/Tumor Dormancy (2004) (0)
Abstract B40: Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties (2013) (0)
3D organotypic models of ductal carcinoma in situ (DCIS): Models for assessing stromal effects on progression to invasion and increased proteolysis (2008) (0)
Relationship of lysosomal cathepsin b to metastasis of the b16 melanoma. Abstr. (1981) (0)
Abstract 5036: Induction of highly efficacious anti-tumor activity and modulation of tumor microenvironment: Cell-free off the shelf therapeutic modality (2019) (0)
Therapeutics , Targets , and Chemical Biology Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer (2012) (0)
Su1841 Interaction of DP1 and Cathepsin B in Colon Cancer (2012) (0)
Cathepsin B is more active at acidic pH and regulates airway surface liquid through the cleavage of (2013) (0)
Cancer – Proteases in the Progression and Metastasis (2016) (0)
The International Proteolysis Society (IPS): A Society for Proteolysis, Proteases and Protease Inhibitors (2002) (0)
Abstract B28: Induced expression of Sprouty4 in breast invasive ductal carcinoma cells inhibits ERK MAP kinase and reduces malignant phenotype (2017) (0)
Abstract P1-05-11: Biological characterization of tumor-associated leukocytes in positive and negative lymph node breast cancer patients (2012) (0)
Investigating the Role of Proteases in Aggressiveness of Inflammatory Breast Cancer (2009) (0)
carcinogenesis Cathepsin C is a tissue-specific regulator of squamous Material (2013) (0)
mRNA in murine tumors (1989) (0)
Abstract 2253: Proteases and cytokines in the transition from preinvasive DCIS to invasive breast carcinoma (2010) (0)
Cathepsinn B on invasion and metastasi ss of gastric carcinoma (2007) (0)
Cathespin b-like proteinase identified as inducer of platelet aggregation by tumor cells. Abstr. (1982) (0)

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