Bradley Bernstein
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Biology
Bradley Bernstein's Degrees
- Doctorate Medicine Harvard University
Why Is Bradley Bernstein Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bradley E. Bernstein is a biologist and Professor of Cell Biology at Harvard Medical School. He is Chair of the Department of Cancer Biology at the Dana–Farber Cancer Institute and the Director of the Broad Institute's Gene Regulation Observatory. He is known for contributions to the fields of epigenetics and cancer biology.
Bradley Bernstein's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Model-based Analysis of ChIP-Seq (MACS) (2008) (11787)
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome (2009) (6558)
- A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells (2006) (5120)
- Integrative analysis of 111 reference human epigenomes (2015) (4979)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells (2007) (4164)
- Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals (2009) (3820)
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma (2014) (3192)
- Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression (2009) (2770)
- Genome-scale DNA methylation maps of pluripotent and differentiated cells (2008) (2515)
- In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state (2007) (2319)
- Active genes are tri-methylated at K4 of histone H3 (2002) (2114)
- An integrated encyclopedia of DNA elements in the human genome (2012) (2080)
- The Mammalian Epigenome (2007) (2072)
- Mapping and Analysis of Chromatin State Dynamics in Nine Human Cell Types (2011) (1925)
- ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia (2012) (1701)
- The NIH Roadmap Epigenomics Mapping Consortium (2010) (1680)
- Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse (2005) (1564)
- Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants (2014) (1487)
- A User's Guide to the Encyclopedia of DNA Elements (ENCODE) (2011) (1467)
- Initial genome sequencing and analysis of multiple myeloma (2011) (1385)
- Systematic analysis of chromatin state dynamics in nine human cell types (2011) (1355)
- Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer (2017) (1265)
- Charting a dynamic DNA methylation landscape of the human genome (2013) (1149)
- Cohesin Loss Eliminates All Loop Domains (2017) (1140)
- Charting histone modifications and the functional organization of mammalian genomes (2011) (1112)
- Dissecting direct reprogramming through integrative genomic analysis (2008) (1058)
- Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains (2008) (1010)
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma (2019) (1007)
- Insulator dysfunction and oncogene activation in IDH mutant gliomas (2015) (950)
- Epigenetic plasticity and the hallmarks of cancer (2017) (789)
- Methylation of histone H3 Lys 4 in coding regions of active genes (2002) (784)
- Expanded encyclopaedias of DNA elements in the human and mouse genomes (2020) (765)
- Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma (2016) (731)
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells (2014) (712)
- Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state (2015) (673)
- Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications (2010) (673)
- Defining functional DNA elements in the human genome (2014) (647)
- Epigenetic Reprogramming in Cancer (2013) (640)
- Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation (2015) (628)
- Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq (2017) (612)
- The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism (2012) (580)
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types (2017) (578)
- Dissecting direct reprogramming through integrative genomic analysis (2008) (534)
- ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. (2012) (522)
- Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues (2013) (511)
- Jarid2 and PRC2, partners in regulating gene expression. (2010) (488)
- Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses (2009) (483)
- Alzheimery's disease pathology is associated with early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci (2014) (482)
- Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity (2019) (460)
- Genomewide studies of histone deacetylase function in yeast. (2000) (426)
- GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells (2010) (418)
- DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina (2012) (416)
- Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells (2013) (409)
- Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci (2014) (402)
- Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins (2013) (398)
- Signaling Network Model of Chromatin (2002) (397)
- Global nucleosome occupancy in yeast (2004) (393)
- Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types (2011) (381)
- Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq (2018) (368)
- A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. (2012) (367)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Reprogramming factor expression initiates widespread targeted chromatin remodeling. (2011) (359)
- Locus-specific editing of histone modifications at endogenous enhancers using programmable TALE-LSD1 fusions (2013) (357)
- Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes (2006) (340)
- Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells (2011) (328)
- Comparative analysis of metazoan chromatin organization (2014) (325)
- Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. (2017) (320)
- Heterodimeric JAK-STAT Activation as a Mechanism of Persistence to JAK2 Inhibitor Therapy (2011) (309)
- A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression (2017) (308)
- An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia (2014) (307)
- Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. (2009) (305)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014) (296)
- Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo (2013) (289)
- Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. (2003) (286)
- Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq (2018) (274)
- Test performance evaluation of SARS-CoV-2 serological assays (2020) (266)
- SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing. (2013) (249)
- Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity (2012) (247)
- An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. (2013) (240)
- Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells (2011) (227)
- SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation (2016) (226)
- Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains (2011) (216)
- Resolving medulloblastoma cellular architecture by single-cell genomics (2019) (213)
- Moving AHEAD with an international human epigenome project (2008) (202)
- An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma (2016) (195)
- Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth (2011) (186)
- Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens (2017) (185)
- Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma (2018) (183)
- Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing (2021) (180)
- Widespread RNA binding by chromatin-associated proteins (2016) (179)
- Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq (2011) (179)
- H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions (2012) (173)
- Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors (2010) (173)
- Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation (1997) (171)
- Dissecting neural differentiation regulatory networks through epigenetic footprinting (2014) (170)
- Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. (2012) (161)
- Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia (2014) (153)
- Transcription elongation factors represent in vivo cancer dependencies in glioblastoma (2017) (147)
- Comparative analysis of metazoan chromatin (2014) (137)
- Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in the aging and Alzheimer human brain (2018) (134)
- Systematic dissection of genomic features determining transcription factor binding and enhancer function (2017) (132)
- Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer (2017) (127)
- Evaluation of SARS-CoV-2 serology assays reveals a range of test performance (2020) (125)
- Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA (2010) (123)
- Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution (2018) (121)
- Development and validation of a T7 based linear amplification for genomic DNA (2003) (119)
- EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas (2011) (116)
- Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. (2018) (113)
- Single-molecule decoding of combinatorially modified nucleosomes (2016) (112)
- Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma. (2014) (112)
- Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital (2020) (109)
- Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors (2019) (102)
- Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. (2019) (102)
- A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. (2016) (100)
- Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity (2021) (99)
- Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. (2018) (95)
- Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma. (2015) (91)
- Chromatin state maps: new technologies, new insights. (2008) (89)
- SEMAPHORE1 functions during the regulation of ancestrally duplicated knox genes and polar auxin transport in maize. (2002) (84)
- Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (2010) (82)
- Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs (2019) (82)
- Rpd3p relocation mediates a transcriptional response to rapamycin in yeast. (2004) (81)
- Test performance evaluation of SARS-CoV-2 serological assays (2020) (80)
- EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. (2015) (80)
- Perspectives on ENCODE (2020) (79)
- Perspectives on ENCODE (2020) (79)
- Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. (2010) (78)
- Targeted DNA Demethylation and Endogenous Gene Activation Using Programmable TALE-TET1 Fusions (2013) (75)
- Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer (2020) (74)
- High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics (2015) (71)
- Genome-wide analysis of histone modifications by ChIP-on-chip. (2006) (68)
- Crystal structures of substrates and products bound to the phosphoglycerate kinase active site reveal the catalytic mechanism. (1998) (65)
- Digital transcriptome profiling from attomole-level RNA samples. (2010) (65)
- High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts (2020) (64)
- Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis (2014) (63)
- Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM (2017) (62)
- In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites (2013) (57)
- A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas. (2017) (57)
- Pluripotent Chromatin State (2009) (55)
- Genetic Events That Shape the Cancer Epigenome (2012) (55)
- Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL (2019) (54)
- Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs (2019) (49)
- The use of chromatin immunoprecipitation assays in genome-wide analyses of histone modifications. (2004) (47)
- RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. (2016) (46)
- A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei. (1998) (40)
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types (2018) (39)
- Epigenome editing strategies for the functional annotation of CTCF insulators (2019) (38)
- Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis. (2019) (37)
- Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance (2020) (37)
- Genomic views of chromatin. (2005) (33)
- Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo (2019) (28)
- Gain-of-function genetic alterations of G9a drive oncogenesis. (2020) (27)
- Data-driven polymer model for mechanistic exploration of diploid genome organization (2020) (27)
- A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. (2012) (23)
- Cohesin loss eliminates all loop domains, leading to links among superenhancers and downregulation of nearby genes (2017) (22)
- Chromatin accessibility promotes hematopoietic and leukemia stem cell activity (2020) (22)
- A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma. (2012) (21)
- Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition. (1994) (21)
- Tumor mutational landscape is a record of the pre-malignant state (2019) (20)
- Global approaches to chromatin. (2002) (20)
- Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations (2022) (19)
- Single cell RNA-seq reveals developmental plasticity with coexisting oncogenic and immune evasion programs in ETP-ALL. (2020) (19)
- The importance of dynamic light scattering in obtaining multiple crystal forms of trypanosoma brucei PGK (1998) (16)
- Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease (2014) (15)
- Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies (2020) (14)
- Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells (2021) (14)
- Sequence‐Specific DNA Recognition by Cys2, His2 Zinc Fingers a (1994) (14)
- Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin. (2018) (13)
- A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity (2019) (13)
- ASXL1 Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression (2011) (12)
- Patel glioblastoma Single-cell RNA-seq highlights intratumoral heterogeneity in primary (2014) (12)
- A general method of domain closure is applied to phosphoglycerate kinase and the result compared with the crystal structure of a closed conformation of the enzyme (1998) (11)
- Unbiased reconstruction of a mammalian transcriptional network mediating the differential response to pathogens (2009) (10)
- Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements (2022) (10)
- DNA-protein interactions in high definition (2012) (9)
- Faculty Opinions recommendation of Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. (2009) (9)
- Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): Overview. (2008) (8)
- Detecting sample swaps in diverse NGS data types using linkage disequilibrium (2020) (6)
- Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): II. Second-Strand Synthesis and In Vitro Transcription. (2008) (6)
- Epigenome-wide study uncovers tau pathology-driven changes of chromatin organization in the aging human brain (2018) (6)
- Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations (2021) (6)
- Multi-tissue integrative analysis of personal epigenomes (2021) (6)
- Epigenetic alterations in keratinocyte carcinoma. (2020) (5)
- Large-scale discovery and validation of functional elements in the human genome (2005) (5)
- Antitrypanosomiasis Drug Development Based on Structures of Glycolytic Enzymes (2018) (5)
- Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (2014) (4)
- Erez Lieberman-Aiden Principles of the Human Genome Comprehensive Mapping of Long-Range Interactions Reveals Folding (2012) (4)
- 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. (2016) (4)
- Widespread RNA binding by chromatin-associated proteins (2016) (4)
- Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains (2018) (4)
- Author response: Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer (2017) (4)
- Notch-Regulated Enhancers in B-Cell Lymphoma Activate MYC and Potentiate B-Cell Receptor Signaling (2016) (3)
- Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): III. Sample Purification. (2008) (3)
- Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase. (2008) (3)
- Genome-wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease (2012) (3)
- Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors (2019) (3)
- Conditional Deletion of Asxl1 Results in Myelodysplasia (2012) (3)
- Epigenetic clocks, aging, and cancer (2022) (3)
- Sequencing the Epigenome (2009) (2)
- Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins (2013) (2)
- The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models (2022) (2)
- Probing the limits of the molecular replacement method: the case of Trypanosoma brucei phosphoglycerate kinase. (1997) (2)
- Integrative analysis of 111 reference human epigenomes Open (2015) (2)
- HOXA9 Is a Novel Therapeutic Target in Multiple Myeloma. (2009) (2)
- Highly Potent Bisphosphonate Ligands for Phosphoglycerate Kinase and Protein Binding Studies (1999) (2)
- Evaluation of SARS-CoV-2 serology assays reveals a range of test performance (2020) (2)
- Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (2)
- SYSTEMS BIOLOGY: GLOBAL REGULATION OF GENE EXPRESSION (2010) (2)
- H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions (2012) (1)
- GABPβ1L Wakes Up TERT. (2018) (1)
- Abstract 4782: Epigenetic resistance to Notch inhibition in T cell acute lymphoblastic leukemia (2014) (1)
- DNA-protein interactions in high definition (2012) (1)
- Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance (2020) (1)
- Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains (2011) (1)
- 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. (2016) (1)
- Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq (2018) (1)
- modENCODE consortia ChIP-seq guidelines and practices of the ENCODE and Material Supplemental (2012) (1)
- An Autoimmune Transcriptional Circuit Driving Foxp3+ Regulatory T cell Dysfunction (2022) (1)
- Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma (2022) (1)
- Human Genome Interactions Reveals Folding Principles of the Comprehensive Mapping of Long-Range (2009) (1)
- Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution (2021) (1)
- Faculty Opinions recommendation of Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. (2008) (1)
- Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins (2013) (1)
- Abstract 877: Evolution of resistance to EGFR inhibition from drug tolerant cancer cells (2016) (1)
- TERNARY COMPLEX OF PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI (1997) (0)
- Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALL (2019) (0)
- Development of ERG-Enhancer Fluorescent Reporter System to Decipher Functional Heterogeneity in Leukemia (2018) (0)
- Faculty Opinions recommendation of A genomic code for nucleosome positioning. (2006) (0)
- Abstract IA06: Epigenetic regulation and heterogeneity in cancer (2013) (0)
- MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA (2018) (0)
- Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin (2022) (0)
- Chromatin accessibility promotes hematopoietic and leukemia stem cell activity (2020) (0)
- Cancer Cell Previews GABP b 1 L Wakes Up TERT (2018) (0)
- Abstract 1132: Multiplexed immunofluorescence and multispectral imaging-based quantification of tumor and immune cell populations reveals spatial relationships in oral cavity squamous cell carcinoma (2019) (0)
- Single-Cell Analysis of AML Reveals Determinants of Disease Progression and Immune Evasion (2018) (0)
- Author Correction: Perspectives on ENCODE (2022) (0)
- Phosphoglycerate kinase from Trypanosoma brucei: selective inhibitors, homology modeling and crystallization (1996) (0)
- Abstract PO-103: Characterizing epigenetic and genetic mechanisms of glioma drug resistance using simultaneous lineage tracing and single-cell transcriptomic analysis (2020) (0)
- Abstract 3479: Modeling epigenetic lesions that cause gliomas (2023) (0)
- Author Correction: Perspectives on ENCODE (2022) (0)
- patterning provide context and positional information in Shh-directed neural Neural-specific Sox 2 input and differential Gli-binding affinity (2012) (0)
- STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA. (2015) (0)
- Faculty Opinions recommendation of Chromosomal distribution of PcG proteins during Drosophila development. (2006) (0)
- Chabner Colloquium: Answering the Big Questions in Cancer Research & 2016 STO Annual Meeting (Boston, MA: November 11-12, 2016) (2016) (0)
- Abstract PO009: Epigenetic silencing by SETDB1 represses tumor-cell intrinsic immunogenicity (2021) (0)
- Title Comparative analysis of metazoan chromatin organization Permalink (2014) (0)
- Resource Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells (2013) (0)
- DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES. (2017) (0)
- MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA (2018) (0)
- Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors (2019) (0)
- Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution (2018) (0)
- Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo (2019) (0)
- Cancer Cell ASXL 1 Loss Inhibits PRC 2 in Myeloid Leukemia syndrome and z 10 % – 15 % of patients with myeloproliferative neoplasms and acute myeloid leukemia (2012) (0)
- ReviewGlobal Approaches to Chromatin A third area in which systematic approaches are yield - (2002) (0)
- Author Correction: Perspectives on ENCODE (2022) (0)
- Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors (2019) (0)
- Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
- Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
- Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation (2014) (0)
- Abstract IA01: Epigenetic mechanisms of tumor initiation and evolution (2016) (0)
- Faculty Opinions recommendation of Dynamic interpretation of hedgehog signaling in the Drosophila wing disc. (2010) (0)
- Faculty Opinions recommendation of Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. (2007) (0)
- Faculty Opinions recommendation of Differential H3K4 methylation identifies developmentally poised hematopoietic genes. (2009) (0)
- Integrative dissection of gene regulatory elements at base resolution (2022) (0)
- Chromatin complex dependencies reveal targeting opportunities in leukemia (2023) (0)
- Alternative Super-Enhancer States Determine MYC Sensitivity to Notch and Brd4 Inhibitors in T Lymphoblastic Leukemia/Lymphoma (2014) (0)
- 3 p Relocation Mediates a Transcriptional Response to Rapamycin in Yeast repression (2004) (0)
- Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Discovery of Biomarkers Predictive of GSI Response in (2014) (0)
- ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES (2020) (0)
- Multi-tissue integrative analysis of personal epigenomes [preprint] Multi-tissue integrative analysis of personal epigenomes [preprint] you. (2021) (0)
- PDTM-32. RESOLVING MEDULLOBLASTOMA CELLULAR ARCHITECTURE BY SINGLE-CELL GENOMICS (2019) (0)
- Abstract 886: Notch signaling activates B-cell specific enhancers to drive oncogene targets in B-cell lymphoma (2016) (0)
- Additional file 3: Table S2 of Widespread RNA binding by chromatin-associated proteins (2016) (0)
- IMMU-14. REVEALING THE MANY MYELOID STATES IN HUMAN BRAIN TUMORS AND WAYS TO PERTURB THEM (2021) (0)
- A low-input, multiplexed assay for quantitative comparison of chromatin landscapes (2015) (0)
- Faculty Opinions recommendation of Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. (2007) (0)
- database mining and microarray analysis Identification of endothelial cell genes by combined (2015) (0)
- Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity (2018) (0)
- Abstract 2996: Insulator dysfunction and epigenetic oncogene activation in SDH-deficient gastrointestinal stromal tumor (2018) (0)
- Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL (2019) (0)
- CHAPTER 7 DNA linear amplification (2005) (0)
- Global Nucleosome Occupancy in Yeast The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2004) (0)
- Metabolome and Genome Reactome Array : Forging a Link Between (2009) (0)
- Modern Epigenomics DNA Methylomics (2012) (0)
- PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI BISUBSTRATE ANALOG (1998) (0)
- GENT-19. INSULATOR DYSFUNCTION AS AN ONCOGENIC DRIVER IN GLIOMA (2016) (0)
- Additional file 1: Supplementary Figures. of Widespread RNA binding by chromatin-associated proteins (2016) (0)
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