Brenda Schulman
#11,241
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American biochemist and structural biologist
Brenda Schulman's AcademicInfluence.com Rankings
Brenda Schulmanbiology Degrees
Biology
#376
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#677
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#222
USA Rank
Biochemistry
#195
World Rank
#246
Historical Rank
#100
USA Rank
Molecular Biology
#1100
World Rank
#1125
Historical Rank
#203
USA Rank
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Biology
Brenda Schulman's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Brenda Schulman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Brenda Schulman is an American biochemist and structural biologist who is a Director at the Max Planck Institute of Biochemistry, Martinsried, Bavaria. Schulman's research interests focus on a class of proteins known as ubiquitin-like proteins.
Brenda Schulman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex (2002) (1420)
- Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. (2009) (1048)
- Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways (2009) (772)
- Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation (2008) (697)
- Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity (2020) (623)
- Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex (2000) (598)
- JAK mutations in high-risk childhood acute lymphoblastic leukemia (2009) (569)
- Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. (2014) (522)
- Structure of a -TrCP1-Skp1--Catenin Complex (2003) (497)
- A Calcium-Regulated MEF2 Sumoylation Switch Controls Postsynaptic Differentiation (2006) (460)
- The SOCS box: a tale of destruction and degradation. (2002) (440)
- Parkin Is a Component of an SCF-like Ubiquitin Ligase Complex and Protects Postmitotic Neurons from Kainate Excitotoxicity (2003) (393)
- Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. (2003) (388)
- Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. (2009) (384)
- Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A. (1998) (374)
- Protein neddylation: beyond cullin–RING ligases (2014) (358)
- Role of the F-box protein Skp2 in lymphomagenesis (2001) (318)
- Building and remodelling Cullin–RING E3 ubiquitin ligases (2013) (268)
- Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase. (2005) (267)
- Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins. (2007) (266)
- The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein (2004) (261)
- The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. (2003) (247)
- E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. (2009) (245)
- N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex (2011) (245)
- Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins (2014) (243)
- A residue-specific NMR view of the non-cooperative unfolding of a molten globule (1997) (243)
- Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex. (2009) (239)
- Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy (2015) (237)
- Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments. (2018) (219)
- Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8 (2003) (208)
- Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity (2007) (199)
- Structural assembly of cullin-RING ubiquitin ligase complexes. (2010) (197)
- biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes (2016) (189)
- Identification and Characterization of the First Small Molecule Inhibitor of MDMX* (2010) (189)
- Structural regulation of cullin-RING ubiquitin ligase complexes. (2011) (184)
- Different subdomains are most protected from hydrogen exchange in the molten globule and native states of human alpha-lactalbumin. (1995) (178)
- E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer (2005) (173)
- Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1. (2005) (172)
- Atomistic Autophagy: The Structures of Cellular Self-Digestion (2014) (156)
- The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein. (2004) (155)
- Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8 (2014) (153)
- Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation (2016) (152)
- Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay (2016) (145)
- Structural basis for a reciprocal regulation between SCF and CSN. (2012) (144)
- SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer. (2014) (142)
- Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. (2011) (135)
- A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 (2004) (134)
- Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 (2013) (130)
- NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly (2020) (130)
- APC15 mediates CDC20 autoubiquitylation by APC/CMCC and disassembly of the mitotic checkpoint complex (2012) (130)
- Identification of a Multifunctional Binding Site on Ubc9p Required for Smt3p Conjugation* (2002) (129)
- System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. (2016) (126)
- Structural Complexity in Ubiquitin Recognition (2006) (125)
- Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism. (2013) (124)
- α-Lactalbumin forms a compact molten globule in the absence of disulfide bonds (1999) (117)
- Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. (2016) (116)
- Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C (2016) (113)
- Mechanism of APC/CCDC20 activation by mitotic phosphorylation (2016) (109)
- A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. (2016) (106)
- A dual E3 mechanism for Rub1 ligation to Cdc53. (2010) (101)
- Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly. (2014) (99)
- Quantifying the heterogeneity of macromolecular machines by mass photometry (2019) (98)
- TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes (2013) (95)
- Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes. (2013) (94)
- IDH1 and IDH2 mutations in pediatric acute leukemia (2011) (93)
- Ubiquitin-like protein activation (2004) (89)
- Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. (2019) (87)
- Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain. (2012) (82)
- RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex (2015) (80)
- Proline scanning mutagenesis of a molten globule reveals non-cooperative formation of a protein's overall topology (1996) (80)
- Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures (2012) (79)
- ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space (2015) (78)
- Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways (2010) (75)
- Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. (2012) (75)
- PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia. (2015) (72)
- Structure of a -TrCP1-Skp1--Catenin Complex: Destruction Motif Binding and Lysine Specificity (2003) (68)
- Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a non-covalent ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway. (2007) (66)
- Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase (2017) (64)
- EM Structure of human APC/CCDH1-EMI1 reveals multimodal mechanism of E3 ligase shutdown (2013) (63)
- A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT (2001) (63)
- Structural Basis of the Cks 1-Dependent Recognition of p 27 Kip 1 by the SCFSkp 2 Ubiquitin Ligase (2005) (61)
- A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits (2020) (61)
- The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7. (2012) (60)
- How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic (2009) (59)
- Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation* (2015) (59)
- Disulfide determinants of calcium-induced packing in alpha-lactalbumin. (1996) (55)
- Structural analysis of Escherichia coli ThiF. (2005) (54)
- Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2 (2008) (54)
- Cullin-RING Ubiquitin Ligase Regulatory Circuits: a Quarter Century Beyond the F-box Hypothesis. (2021) (54)
- Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26–APC6 structure (2009) (53)
- NEDD8 and ubiquitin ligation by cullin-RING E3 ligases. (2020) (52)
- Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly (2021) (52)
- Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly. (2019) (51)
- Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology (2020) (49)
- A RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases (2011) (48)
- Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways (2010) (47)
- High-level expression and purification of recombinant SCF ubiquitin ligases. (2005) (46)
- Twists and turns in ubiquitin‐like protein conjugation cascades (2011) (46)
- Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 (2008) (44)
- Hydrogen-oxidizing electron transport components in the hyperthermophilic archaebacterium Pyrodictium brockii (1992) (43)
- Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1 (2017) (42)
- Does the molten globule have a native-like tertiary fold? (1995) (42)
- Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination. (2016) (41)
- Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients (2020) (37)
- Cullin neddylation and substrate‐adaptors counteract SCF inhibition by the CAND1‐like protein Lag2 in Saccharomyces cerevisiae (2009) (36)
- SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression (2013) (34)
- Expression, purification, and characterization of the E1 for human NEDD8, the heterodimeric APPBP1-UBA3 complex. (2005) (34)
- Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways (2019) (34)
- Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. (2018) (33)
- The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test (2014) (33)
- Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. (2015) (33)
- ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. (2019) (30)
- Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1 (2013) (29)
- The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma (2021) (28)
- A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade (2019) (28)
- Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. (2018) (27)
- Distinct Functional Domains of Ubc9 Dictate Cell Survival and Resistance to Genotoxic Stress (2006) (27)
- Structural and Dynamic Independence of Isopeptide-linked RanGAP1 and SUMO-1* (2004) (27)
- The structural context of posttranslational modifications at a proteome-wide scale (2022) (23)
- GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme (2021) (22)
- Decoding the messaging of the ubiquitin system using chemical and protein probes. (2021) (22)
- Binding to E1 and E3 is mutually exclusive for the human autophagy E2 Atg3 (2013) (20)
- Molecular glue concept solidifies (2019) (19)
- Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis (2020) (19)
- How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini (2022) (19)
- Inhibition of papain-like protease PLpro blocks SARS-CoV-2 spread and promotes anti-viral immunity (2020) (18)
- Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity (2020) (17)
- Local and Global Cooperativity in the Human α-Lactalbumin Molten Globule (2004) (17)
- Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site (2019) (17)
- FBXO11-Mediated Proteolysis of BAHD1 Relieves PRC2-dependent Transcriptional Repression in Erythropoiesis. (2020) (17)
- Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4 (2017) (16)
- Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20 (2020) (16)
- An expanded lexicon for the ubiquitin code (2022) (16)
- Discovery of Novel Pyrazolo-Pyridone DCN1 Inhibitors Controlling Cullin Neddylation. (2019) (16)
- The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains (2021) (15)
- In situ structural analysis reveals membrane shape transitions during autophagosome formation (2022) (15)
- Probing subtle differences in the hydrogen exchange behavior of variants of the human alpha-lactalbumin molten globule using mass spectrometry. (2001) (14)
- APC15 mediates CDC20 auto-ubiquitylation by APC/CMCC and MCC disassembly (2012) (13)
- Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler (2020) (13)
- Disulfide Determinants of Calcium-Induced Packing in R-Lactalbumin † (13)
- System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1, Ubv P2.3 and UBCH7 (2016) (13)
- DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift (2020) (13)
- Ubiquitin-like modifiers. (2012) (12)
- Hydrogen exchange in BPTI variants that do not share a common disulfide bond (1994) (12)
- Protein ubiquitination: CHIPping away the symmetry. (2005) (12)
- CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation (2021) (12)
- Allosteric regulation through a switch element in the autophagy E2, Atg3 (2020) (9)
- Multifaceted N-degron recognition and ubiquitylation by GID/CTLH E3 ligases. (2021) (8)
- Breaking up with a kinky SUMO (2006) (8)
- Structural biology: A protein engagement RING (2012) (8)
- Insights into the ubiquitin transfer cascade from the structure of the E1 for NEDD8. (2003) (8)
- Measuring APC/C-Dependent Ubiquitylation In Vitro. (2016) (8)
- Hydrogen-sulfur autotrophy in the hyperthermophilic archaebacterium, Pyrodictium brockii. (1990) (7)
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1 (2009) (6)
- A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters (2021) (6)
- Production of Human ATG Proteins for Lipidation Assays. (2017) (5)
- Local and global cooperativity in the human alpha-lactalbumin molten globule. (2004) (3)
- Multifaceted N-degron recognition and ubiquitylation by GID/CTLH E3 ligases (2021) (3)
- Tag-team SUMO wrestling. (2005) (3)
- Dual RING E 3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC / C Graphical (3)
- Dual-color pulse-chase ubiquitination assays to simultaneously monitor substrate priming and extension. (2019) (3)
- (G2)BRinging an E2 to E3. (2009) (2)
- Supplemental Data E 2-RING Expansion of the NEDD 8 Cascade Confers Specificity to Cullin Modification (2009) (2)
- SCF E3 Ligase Substrates Switch from CAN-D to Can-ubiquitylate. (2018) (2)
- The structural context of PTMs at a proteome wide scale (2022) (2)
- E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. (2023) (2)
- Structure of APPBP1-UBA3-Ubc12N26: a unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 (2004) (2)
- APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex (2003) (2)
- Integrative proteomics reveals principles of dynamic phospho-signaling networks in human erythropoiesis (2020) (2)
- Trans mechanism for ubiquitin-like protein transfer in autophagy (2012) (2)
- Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M (2021) (2)
- New classes of E3 ligases illuminated by chemical probes. (2022) (2)
- APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain (2021) (1)
- APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C (2016) (1)
- Abstract LB-056: Discovery of novel small molecule inhibitors of the DCN1-Ubc12 interaction by high throughput screening technology (2016) (1)
- Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Ala-NEDD8Ala72Arg) (2008) (1)
- The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test (2014) (1)
- Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation (2022) (1)
- Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report (2022) (1)
- Differential UBE2H-CTLH E2-E3 ubiquitylation modules regulate erythroid maturation (2022) (1)
- Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly (2019) (1)
- Twists and Turns in Ubiquitin Conjugation Cascades (2013) (1)
- Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation (2022) (1)
- Systemwide disassembly and assembly of SCF ubiquitin ligase complexes (2023) (1)
- Crystallographic Characterization of ATG Proteins and Their Interacting Partners. (2017) (1)
- First Small Molecule Inhibitor of MDMX Identification and Characterization of the Cell Biology : (2010) (1)
- Structural biology: Transformative encounters (2010) (1)
- Structure of DCN1 bound to NAcM-COV (2017) (0)
- Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 (2021) (0)
- Faculty Opinions recommendation of Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. (2013) (0)
- 'Ubiquitylation: mechanism and functions' review series (2013) (0)
- Structural Studies of Ubiquitin and Ubiquitin-Like Protein Transfer Cascades (2011) (0)
- Author response: Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways (2019) (0)
- Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 (2020) (0)
- Structure of yeast Fbp1 (Fructose-1,6-bisphosphatase 1) (2021) (0)
- Crystal structure of E. coli MccB + ATP (2009) (0)
- Crystal structure of APC11 RING domain (2014) (0)
- Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination (2016) (0)
- Structure of a Glomulin-RBX1-CUL1 complex (2012) (0)
- Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide (2019) (0)
- Structure of (3S,4S)-1-benzyl-4-(3-(3-(trifluoromethyl)phenyl)ureido)piperidin-3-yl acetate bound to DCN1 (2018) (0)
- Crystal structure of the Skp1-Skp2-Cks1 complex (2005) (0)
- Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate (2021) (0)
- APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP (2003) (0)
- Team-tagging ubiquitin ligation pathways (2017) (0)
- DIA-based systems biology approach unveils novel E3-dependent responses to a metabolic shift (2020) (0)
- Host ubiquitin protein tags lipid to fight bacteria (2021) (0)
- NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly (2020) (0)
- Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 (2021) (0)
- Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 (2021) (0)
- yeast Cul1WHB-Dcn1P acetylated Ubc12N complex (2011) (0)
- Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs (2020) (0)
- N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-stapled acetylated Ubc12N complex (2011) (0)
- The GID E3 Ubiquitin Ligase Converts Between Anticipatory and Active States Through the Incorporation of Swappable Substrate Receptors (2020) (0)
- PNAS Plus Significance Statements (2016) (0)
- Crystal structure of E. coli MccB + SeMet MccA (2009) (0)
- Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* (2021) (0)
- Crystal structure of S. cerevisiae Atg8 in complex with Ede1 (1220-1247) (2020) (0)
- 3D solution structure of EMI1 (Early Mitotic Inhibitor 1) (2013) (0)
- Crystal structure of APC3 (2014) (0)
- Structure of 1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea bound to DCN1 (2018) (0)
- FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1 (2018) (0)
- Isolated Ring domain (2014) (0)
- Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly (2021) (0)
- A Protein Engineering Approach for Uncovering Cryptic Ubiquitin-binding Sites: from a Ubiquitin-Variant Inhibitor of APC/C to K48 Chain Binding (2019) (0)
- Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide (2019) (0)
- Structure of ScAtg3 with truncations in N-terminal and flexible region (FR) (2019) (0)
- Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution (2016) (0)
- Mechanistic Insights into the NEDD8 Conjugation Cascade (2008) (0)
- In situ snapshots along a mammalian selective autophagy pathway (2023) (0)
- Twists and turns in Ubiquitin Conjugation Cascades (2016) (0)
- Crystal structure of NEDD4 LIR-fused human LC3B_2-119 (2017) (0)
- Crystal structure of E. coli MccB + MccA-N7isoASN (2009) (0)
- Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs (2020) (0)
- Structural studies of the alpha-lactalbumin molten globule : implications for protein folding (1995) (0)
- Structure of DCN4 PONY domain bound to CUL1 WHB (2017) (0)
- Respiratory Electron-Transport Components in Hyperthermophilic Bacteria (1992) (0)
- Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase (2021) (0)
- Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain (2019) (0)
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1 (2009) (0)
- Cryo-EM structure of human ER membrane protein complex in GDN detergent (2020) (0)
- A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution (2010) (0)
- 5 Ubiquitin-like modifiers (2012) (0)
- Crystal structure of Atg7 NTD K14A F16A D18A mutant (2012) (0)
- Crystal structure of E. coli MccB + AMPCPP + SeMeT MccA (2009) (0)
- Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to a Fab in DDM detergent (2020) (0)
- Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C) (2016) (0)
- Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide (2005) (0)
- Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex (2007) (0)
- Insights into the ISG15 transfer cascade by the UBE1L activating enzyme (2023) (0)
- IDH1 and IDH2 Mutations In Pediatric Acute Myeloid Leukemia (2010) (0)
- Structure Previews ( G 2 ) BRinging an E 2 to E 3 (0)
- E2~Ubiquitin-HECT (2010) (0)
- Catalytic module of yeast Chelator-GID SR4 E3 ubiquitin ligase (2021) (0)
- Structural insights into ubiquitin-like protein transfer cascades (2005) (0)
- A role of autophagy in spinocerebellar ataxia—Rare exception or general principle? (2016) (0)
- Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density (2016) (0)
- Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology (2021) (0)
- Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms (2016) (0)
- 502 SUMO conjugation and proteolysis regulate cell sensitivity to DNA topoisomerase I poisons (2004) (0)
- PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems (2023) (0)
- Crystal structure of APC3-APC16 complex (Selenomethionine Derivative) (2014) (0)
- Crystal structure of APC3-APC16 complex (2014) (0)
- Structure of CRL7FBXW8 reveals coupling with CUL1–RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation (2022) (0)
- APC11 binding Ubiquitin Variant (2018) (0)
- Electron Transport Components inthe Hyperthermophilic Archaebacterium Pyrodictium brockii (1992) (0)
- Cryo-EM Studies Capturing Dynamic Intermediates in Ubiquitin Conjugation (2018) (0)
- A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) (2010) (0)
- System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1 (2016) (0)
- Cryo-EM ofMitotic Checkpo int Complex-Bound APC / C RevealsReciprocalandConformationalRegulationof Ubiquitin Ligation Graphical (2016) (0)
- Crystal structure of E. coli MccB (2009) (0)
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases:SPOPMATHx-PucSBC1_pep2 (2009) (0)
- Quantifying the heterogeneity of macromolecular machines by mass photometry (2020) (0)
- Crystal Structure of E2 Complex (2015) (0)
- Supramolecular assembly module of yeast Chelator-GID SR4 E3 ubiquitin ligase (2021) (0)
- Chapter 10. E3-mediated Ubiquitin and Ubiquitin-like Protein Ligation: Mechanisms and Chemical Probes (2020) (0)
- Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27 (2021) (0)
- Resource System-Wide Modulation o f HECT E 3 Ligases with Selective Ubiquitin Variant Probes Graphical Abstract Highlights (2016) (0)
- Crystal structure of E. coli MccB + Succinimide (2009) (0)
- Methods Preparation of Proteins and Antibodies Puri®cation of Pid from Nuclear Extracts P53 Deacetylation Assay (0)
- Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action (2014) (0)
- A cause for childhood ataxia Genetic studies uncover a mutation in a widely conserved protein as the cause of a neurological disorder in two brothers. (2016) (0)
- A central role for regulated protein stability in the control of TFE3 and MITF by nutrients. (2023) (0)
- Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 (2013) (0)
- Crystal structure of an Atg7-Atg10 crosslinked complex (2012) (0)
- Crystal structure of RBR ubiquitin ligase ARIH2 (2021) (0)
- DCNL complex with N-terminally acetylated NEDD8 E2 peptide (2012) (0)
- Author response: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 (2013) (0)
- Activity-based profiling of cullin-RING ligase networks by conformation-specific probes (2023) (0)
- Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. (2021) (0)
- HHARI/ARIH1-UBCH7~Ubiquitin (2017) (0)
- Structure of DCN1 bound to N-((4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(trifluoromethyl)benzamide (2021) (0)
- Huib Ovaa (1973–2020) (2020) (0)
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