Brian Kuhlman
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Chemistry Physics
Brian Kuhlman's Degrees
- PhD Biophysics University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Brian Kuhlman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Brian A. Kuhlman is an American professor of biochemistry and biophysics at the UNC School of Medicine of University of North Carolina at Chapel Hill and a Sloan Research Fellow. Early life Kuhlman obtained Bachelor of Arts degree in chemical physics from Rice University in 1992. From 1993 to 1998 he studied under guidance of Daniel Raleigh to earn his Ph.D. in chemistry from Stony Brook University and from 1999 to 2002 he studied under guidance from David Baker to obtain Damon Runyon Postdoctoral Fellowship at the University of Washington.
Brian Kuhlman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Design of a Novel Globular Protein Fold with Atomic-Level Accuracy (2003) (1522)
- ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. (2011) (1504)
- Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations. (2003) (1051)
- A genetically-encoded photoactivatable Rac controls the motility of living cells (2009) (979)
- The Rosetta all-atom energy function for macromolecular modeling and design (2017) (788)
- Native protein sequences are close to optimal for their structures. (2000) (785)
- Labelling and optical erasure of synaptic memory traces in the motor cortex (2015) (488)
- Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins (2014) (429)
- Advances in protein structure prediction and design (2019) (388)
- Macromolecular modeling and design in Rosetta: recent methods and frameworks (2020) (339)
- A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins. (2003) (310)
- Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE) (2013) (302)
- LOVTRAP, An Optogenetic System for Photo-induced Protein Dissociation (2016) (222)
- Computer-based redesign of a protein folding pathway (2001) (216)
- Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface (2014) (203)
- Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta. (2015) (202)
- Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates (2009) (192)
- Scientific benchmarks for guiding macromolecular energy function improvement. (2013) (191)
- RosettaDesign server for protein design (2006) (189)
- Computational design of a single amino acid sequence that can switch between two distinct protein folds. (2006) (176)
- An improved protein decoy set for testing energy functions for protein structure prediction (2003) (174)
- E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer (2005) (173)
- Designing photoswitchable peptides using the AsLOV2 domain. (2012) (168)
- A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds (2013) (150)
- A “solvated rotamer” approach to modeling water‐mediated hydrogen bonds at protein–protein interfaces (2005) (146)
- Computational design of affinity and specificity at protein-protein interfaces. (2009) (140)
- Community-wide assessment of protein-interface modeling suggests improvements to design methodology. (2011) (139)
- Computer-based design of novel protein structures. (2006) (133)
- Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 (2013) (130)
- Metal templated design of protein interfaces (2009) (128)
- High-resolution design of a protein loop (2007) (123)
- Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrate. (2011) (123)
- Structure-based design of supercharged, highly thermoresistant antibodies. (2012) (121)
- Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon. (2016) (115)
- Design of structurally distinct proteins using strategies inspired by evolution (2016) (114)
- pKa values and the pH dependent stability of the N-terminal domain of L9 as probes of electrostatic interactions in the denatured state. Differentiation between local and nonlocal interactions. (1999) (114)
- Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C (2016) (113)
- A preliminary survey of the peptoid folding landscape. (2009) (108)
- Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering. (2012) (107)
- Design of protein conformational switches. (2006) (103)
- Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. (2007) (102)
- Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 (2016) (99)
- Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. (2012) (96)
- Site–Specific Monoubiquitination Activates Ras by Impeding GTPase Activating Protein Function (2012) (96)
- Exploring folding free energy landscapes using computational protein design. (2004) (95)
- Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides. (2017) (91)
- Global analysis of the effects of temperature and denaturant on the folding and unfolding kinetics of the N-terminal domain of the protein L9. (1998) (89)
- High-resolution Structural and Thermodynamic Analysis of Extreme Stabilization of Human Procarboxypeptidase by Computational Protein Design (2007) (87)
- A Generic Program for Multistate Protein Design (2011) (86)
- Evolution of a highly active and enantiospecific metalloenzyme from short peptides (2018) (86)
- Control of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear Translocation (2015) (84)
- Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design (2012) (84)
- Accurate computer-based design of a new backbone conformation in the second turn of protein L. (2002) (82)
- A biosensor generated via high throughput screening quantifies cell edge Src dynamics (2011) (79)
- Conversion of monomeric protein L to an obligate dimer by computational protein design (2001) (79)
- Light-induced nuclear export reveals rapid dynamics of epigenetic modifications (2016) (77)
- A minimal TrpRS catalytic domain supports sense/antisense ancestry of class I and II aminoacyl-tRNA synthetases. (2007) (76)
- Computational design of a PAK1 binding protein. (2010) (76)
- Computational design of a symmetric homodimer using β-strand assembly (2011) (74)
- Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. (2016) (70)
- Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability (2013) (65)
- Engineering a protein–protein interface using a computationally designed library (2010) (63)
- Global analysis of the thermal and chemical denaturation of the N‐terminal domain of the ribosomal protein L9 in H2O and D2O. Determination of the thermodynamic parameters, ΔH°, ΔS°, and ΔC°p, and evaluation of solvent isotope effects (1998) (62)
- Computational protein design with explicit consideration of surface hydrophobic patches (2012) (60)
- Anchored Design of Protein-Protein Interfaces (2011) (60)
- Tuning the Binding Affinities and Reversion Kinetics of a Light Inducible Dimer Allows Control of Transmembrane Protein Localization. (2016) (59)
- Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core. (2012) (58)
- Sequence determinants of E2-E6AP binding affinity and specificity. (2007) (58)
- Supertertiary structure of the MAGUK core from PSD-95. (2013) (56)
- Structure and stability of the N-terminal domain of the ribosomal protein L9: evidence for rapid two-state folding. (1998) (52)
- Lamellipodia are crucial for haptotactic sensing and response (2016) (52)
- The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed (2014) (49)
- Role of electrostatic repulsion in controlling pH-dependent conformational changes of viral fusion proteins. (2013) (48)
- Perturbing the energy landscape for improved packing during computational protein design (2020) (47)
- Adding Diverse Noncanonical Backbones to Rosetta: Enabling Peptidomimetic Design (2013) (47)
- Fab-based bispecific antibody formats with robust biophysical properties and biological activity (2015) (47)
- An Adaptive Dynamic Programming Algorithm for the Side Chain Placement Problem (2004) (46)
- Computationally Designed Bispecific Antibodies using Negative State Repertoires. (2016) (45)
- An exceptionally stable helix from the ribosomal protein L9: implications for protein folding and stability. (1997) (45)
- Go in! Go out! Inducible control of nuclear localization. (2016) (45)
- SwiftLib: rapid degenerate-codon-library optimization through dynamic programming (2014) (44)
- A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. (2018) (44)
- Computational design of the sequence and structure of a protein-binding peptide. (2011) (44)
- Computer-based redesign of a beta sandwich protein suggests that extensive negative design is not required for de novo beta sheet design. (2008) (40)
- Calcium binding peptides from alpha-lactalbumin: implications for protein folding and stability. (1997) (38)
- Protein design simulations suggest that side‐chain conformational entropy is not a strong determinant of amino acid environmental preferences (2005) (38)
- Computational design of second‐site suppressor mutations at protein–protein interfaces (2010) (37)
- Functional Class I and II amino acid-activating enzymes can be coded by opposite strands of the same gene. (2016) (37)
- Cooperative folding of a protein mini domain: the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex. (1998) (34)
- A conformational transition state accompanies tryptophan activation by B. stearothermophilus tryptophanyl-tRNA synthetase. (2007) (34)
- G Protein Mono-ubiquitination by the Rsp5 Ubiquitin Ligase* (2009) (33)
- Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer. (2006) (33)
- Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene* (2015) (30)
- Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design. (2018) (29)
- Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution. (2006) (28)
- Optogenetic control of Cofilin and αTAT in living cells using Z-lock (2019) (26)
- Cells lay their own tracks – optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration (2017) (26)
- Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2 (2002) (24)
- Tryptophanyl-tRNA Synthetase Urzyme (2010) (24)
- Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2. (2002) (23)
- Using quantum mechanics to improve estimates of amino acid side chain rotamer energies (2007) (23)
- Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker (2017) (22)
- Effects of varying the local propensity to form secondary structure on the stability and folding kinetics of a rapid folding mixed alpha/beta protein: characterization of a truncation mutant of the N-terminal domain of the ribosomal protein L9. (1999) (22)
- Rotamer-Pair Energy Calculations Using a Trie Data Structure (2005) (22)
- Hold me tightly LOV (2010) (22)
- Maintaining solvent accessible surface area under rotamer substitution for protein design (2007) (22)
- Folding of the multidomain ribosomal protein L9: the two domains fold independently with remarkably different rates. (1999) (22)
- Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance (2018) (21)
- Kinetics of the transfer of ubiquitin from UbcH7 to E6AP. (2010) (20)
- Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins (2018) (20)
- UbSRD: The Ubiquitin Structural Relational Database. (2016) (20)
- Strategies to control the binding mode of de novo designed protein interactions. (2013) (20)
- Requirements for 5′dRP/AP lyase activity in Ku (2014) (19)
- On-the-Fly Rotamer Pair Energy Evaluation in Protein Design (2008) (19)
- Engineering and Application of LOV2-Based Photoswitches. (2016) (18)
- Engineering a genetically encoded competitive inhibitor of the KEAP1-NRF2 interaction via structure-based design and phage display. (2015) (18)
- Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein α Subunit Mutants* (2010) (18)
- Better together: Elements of successful scientific software development in a distributed collaborative community (2020) (17)
- Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies (2017) (17)
- Computational de novo design of a four‐helix bundle protein—DND_4HB (2015) (17)
- Protocols for Requirement-Driven Protein Design in the Rosetta Modeling Program (2018) (16)
- Probing the minimal determinants of zinc binding with computational protein design. (2016) (16)
- Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling (2021) (14)
- Designing protein structures and complexes with the molecular modeling program Rosetta (2019) (13)
- Engineering Improved Photoswitches for the Control of Nucleocytoplasmic Distribution. (2018) (13)
- Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme (2016) (13)
- Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics (2020) (12)
- Light‐Dependent Cytoplasmic Recruitment Enhances the Dynamic Range of a Nuclear Import Photoswitch (2018) (12)
- Ubiquitin-conjugating Enzyme Cdc34 and Ubiquitin Ligase Skp1-Cullin-F-box Ligase (SCF) Interact through Multiple Conformations* (2014) (12)
- Cages from coils (2013) (11)
- Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications. (2011) (11)
- Combined computational design of a zinc‐binding site and a protein–protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding (2013) (11)
- We FRET so You Don't Have To: New Models of the Lipoprotein Lipase Dimer. (2018) (11)
- Boosting protein stability with the computational design of β‐sheet surfaces (2016) (11)
- From Computational Design to a Protein That Binds (2011) (11)
- Engineering a Protein Binder Specific for p38α with Interface Expansion. (2018) (10)
- Computer-based Engineering of Thermostabilized Antibody Fragments. (2019) (10)
- Global analysis of the thermal and chemical denaturation of the N-terminal domain of the ribosomal protein L9 in H2O and D2O. Determination of the thermodynamic parameters, deltaH(o), deltaS(o), and deltaC(o)p and evaluation of solvent isotope effects. (1998) (9)
- Dimerization of Dengue Virus E Subunits Impacts Antibody Function and Domain Focus (2020) (9)
- Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies (2021) (9)
- Using anchoring motifs for the computational design of protein-protein interactions. (2013) (8)
- PyRosetta Jupyter Notebooks Teach Biomolecular Structure Prediction and Design. (2020) (7)
- Future Challenges Of Computational Protein Design (2009) (7)
- Erratum: Native protein sequences are close to optimal for their structures (Proceedings of the National Academy of Sciences of the United States of America (September 12, 2000) 97 (10383-10388)) (2000) (7)
- Amide proton exchange measurements as a probe of the stability and dynamics of the n‐terminal domain of the ribosomal protein L9: Comparison with the intact protein (1998) (6)
- Macromolecular modeling and design in Rosetta: recent methods and frameworks (2020) (5)
- Erratum: Designing photoswitchable peptides using the AsLOV2 domain (Chemistry and Biology (2012) 19 (507-517)) (2012) (5)
- Computational Repacking of HIF-2α Cavity Replaces Water-Based Stabilized Core. (2016) (5)
- An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation (2020) (5)
- Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks (2021) (5)
- A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins. (2013) (5)
- A computational protocol for regulating protein binding reactions with a light sensitive protein dimer. (2019) (5)
- Data in support of UbSRD: The Ubiquitin Structural Relational Database (2015) (4)
- Designer proteins that competitively inhibit Gαq by targeting its effector site (2021) (4)
- Design and engineering of light-sensitive protein switches. (2022) (3)
- Computer-based Redesign of a β-Sandwich Protein Suggests that Extensive Negative Design is Not Required for De Novo β-Sheet Design (2009) (3)
- Biophysical and structural characterization of novel RAS-binding domains (RBDs) of PI3Kα and PI3Kγ. (2021) (3)
- Dual RING E 3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC / C Graphical (3)
- Redesigning the NEDD8 pathway with a bacterial genetic screen for ubiquitin-like molecule transfer. (2012) (2)
- AlphaFold accurately predicts distinct conformations based on oligomeric state of a de novo designed protein (2022) (2)
- Computational Design of Protein Linkers. (2016) (2)
- Correction: Corrigendum: A biosensor generated via high-throughput screening quantifies cell edge Src dynamics (2012) (2)
- Inside-Out Design of Zinc-Binding Proteins with Non-Native Backbones. (2023) (2)
- Designer installation of a substrate recruitment domain to tailor enzyme specificity (2022) (2)
- Advances in Modular Control of CAR-T Therapy with Adapter-Mediated CARs. (2022) (1)
- Correction to Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design. (2018) (1)
- Correction to "The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design". (2022) (1)
- Erratum to Originally published in PROTEINS: Structure, Function, and Bioinformatics [81(7), (2013), 1245-1255] DOI:10.1002/prot.24280 (2013) (1)
- The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed (2014) (1)
- From Protein Design to the Energy Landscape of a Cold Unfolding Protein (2022) (1)
- Stabilizing proteins, simplified: A Rosetta‐based webtool for predicting favorable mutations (2022) (1)
- A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines (2022) (1)
- Design of a protease‐activated PD‐L1 inhibitor (2023) (1)
- Faculty Opinions recommendation of Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface. (2006) (1)
- Crystal structure of de novo designed MID1-zinc H12E mutant (2012) (0)
- Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A (2014) (0)
- Subunit Mutants α G-Protein Enhancement between GoLoco Motifs and Structural Determinants of Affinity Protein Structure and Folding: (2013) (0)
- Design of An Ultra-Fast Acting Insulin Analog using Unnatural Amino Acids-Replacement of PheB24 with Cyclohexanylalanine (2012) (0)
- Structure of designed zinc binding protein ZE2 bound to Zn2 (2016) (0)
- Designing new protein structures and functions with the molecular modeling program Rosetta (2019) (0)
- Computational Stabilization of T Cell Receptor Constant Domains (2020) (0)
- Fc Heterodimer Design 9.1 Y407M + T366I (2016) (0)
- Typical development workflow in the Rosetta community. (2020) (0)
- SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9 (2002) (0)
- Solution Structure of a repacked version of HIF-2 alpha PAS-B (2016) (0)
- Investigation of cellular signaling and epigenetic dynamics via optogenetic control of nuclear cytoplasmic distribution (2017) (0)
- Faculty Opinions recommendation of An approach to crystallizing proteins by metal-mediated synthetic symmetrization. (2012) (0)
- Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant (2009) (0)
- Crystal structure of de novo designed MID1-cobalt (2012) (0)
- USING AUREOCHROME TO CONTROL PROTEIN-PROTEIN INTERA CTIONS WITH LIGHT (2012) (0)
- Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics (2020) (0)
- Descriptions of the Rosetta board positions. (2020) (0)
- Fc Heterodimer Design 6.1 F405W/Y407A + T366M (2016) (0)
- Author response: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 (2013) (0)
- Solution NMR Structure of a Protein With a Redesigned Hydrophobic Core, Northeast Structural Genomics Consortium Target OR38 (2011) (0)
- Fc Heterodimer Design 7.7 D399M/Y407A + T366V/K409I (2016) (0)
- Engineering and design: editorial overview. (2009) (0)
- Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer (2021) (0)
- Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit (2006) (0)
- Crystal structure of de novo designed MID1-apo1 (2012) (0)
- Combined computational design of a zinc‐binding site and a protein–protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding (2013) (0)
- Erratum: Conversion of monomeric protein L to an obligate dimer by computational protein design (Proceedings of the National Academy of Sciences of the United States of America (September 11, 2001) 98:19 (10687-10691)) (2002) (0)
- Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 2 beta, CRD2b) at 1.42A (2014) (0)
- Fc Heterodimer E356K/D399K + K392D/K409D (2016) (0)
- Crystal structure of de novo designed MID1-zinc H35E mutant (2012) (0)
- Crystal structure of Top7: A computationally designed protein with a novel fold (2003) (0)
- Fc Design 20.8.37 A chain homodimer Y349S/T366M/K370Y/K409V (2016) (0)
- Structure of Spelter bound to Zn2 (2016) (0)
- Solution NMR Structure of Designed Protein DA05R1, Northeast Structural Genomics Consortium (NESG) Target OR690 (2015) (0)
- Computational Design of a Stable DIII Pentamer of Dengue Virus Envelope Protein as an Immunogen with Rosetta (2020) (0)
- Specific tests for Rosetta running on our automated testing framework. (2020) (0)
- Values Statement: Equality and Inclusion in the RosettaCommons. (2020) (0)
- Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A (2014) (0)
- Author Correction: Optogenetic control of cofilin and αTAT in living cells using Z-lock (2020) (0)
- Crystal Structure of De Novo Designed Protein CA01 (2016) (0)
- Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14 (2011) (0)
- Crystal Structures of the redesigned protein G variant NuG1 (2002) (0)
- A Deep-Dive into the Rosetta Energy Function for Biological Macromolecules (2017) (0)
- Structure of Pertuzumab Fab with light chain Clambda at 2.16A (2014) (0)
- Author response: Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 (2016) (0)
- Crystal structure of computationally redesigned gamma-adaptin appendage domain forming a symmetric homodimer (2011) (0)
- Members of the RosettaCommons Consortium. (2020) (0)
- Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A (2014) (0)
- Conditional Mg2+-Assisted Catalysis: A Master Switching Motif Responsible for Differential Stability Suggests a General Transducing Mechanism (2011) (0)
- Commercial spin-off companies from the Rosetta community. (2020) (0)
- Growth in Rosetta PIs and conference attendees. (2020) (0)
- NEW APPROACHES FOR CONTROL AND VISUALIZATION OF PROTEIN CONFORMATION IN LIVE CELLS (2018) (0)
- Crystal Structure of iLID - an Improved Light-Inducible Dimer (2014) (0)
- Analysis of Relative Binding Affinity Predictions for Protein-Protein Complexes (2018) (0)
- Fc Heterodimer Design 2.9 L368M/K370E + E357A/S364G (2016) (0)
- Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A (2016) (0)
- Author response for "Perturbing the energy landscape for improved packing during computational protein design" (2020) (0)
- Solution NMR Structure of De Novo Designed Four Helix Bundle Protein, Northeast Structural Genomics Consortium (NESG) Target OR188 (2012) (0)
- Structure of a G-alpha-i1 mutant with enhanced affinity for the RGS14 GoLoco motif. (2010) (0)
- Fc Heterodimer Design 20.8.34 Y349S/T366M/K370Y/K409V + E356G/E357D/S364Q/Y407A (2016) (0)
- A Systematic Computational Method to Predict and Enhance Antibody-Antigen Binding in the Absence of Antibody Crystal Structures (2012) (0)
- In silico evolution of protein binders with deep learning models for structure prediction and sequence design (2023) (0)
- Fc Design 7.7 B chain homodimer T366V/K409I (2016) (0)
- Resource Computationally Designed Bispecific Antibodies using Negative State Repertoires Graphical Abstract Highlights (2016) (0)
- Fc Heterodimer Design 20.8 Y349S/T366V/K370Y/K409V + E357D/S364Q/Y407A (2016) (0)
- Ras Activity Regulation by Monoubiquitination (2013) (0)
- Faculty Opinions recommendation of Structural basis for the function and inhibition of an influenza virus proton channel. (2008) (0)
- Fc Heterodimer Design 5.1 T366V + Y407F (2016) (0)
- Structure of a photoactivatable Rac1 containing Lov2 Wildtype (2009) (0)
- Fc Heterodimer Design 11.2 Y349S/K370Y + E357D/S364Q (2016) (0)
- Details of Remaining Collective Challenges. (2020) (0)
- De novo design of stable proteins that efficaciously inhibit oncogenic G proteins (2023) (0)
- Fc Heterodimer Design 7.4 Y407A + T366V/K409V (2016) (0)
- Fc Heterodimer Design 8.1 L368V/Y407A + T366V/K409F (2016) (0)
- Comparative Analysis of Sulfonium-π, Ammonium-π, and Sulfur-π Interactions and Relevance to SAM-Dependent Methyltransferases. (2022) (0)
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