Brian Litt
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Biology
Brian Litt's Degrees
- PhD Neuroscience University of Pennsylvania
Why Is Brian Litt Influential?
(Suggest an Edit or Addition)According to Wikipedia, Brian Litt is a Professor of Neurology, Neurosurgery and Bioengineering at the Perelman School of Medicine and University of Pennsylvania. He is the former director of the Penn Epilepsy Center, and is director of the Center for Neuroengineering and Therapeutics.
Brian Litt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. (2010) (1389)
- Flexible, Foldable, Actively Multiplexed, High-Density Electrode Array for Mapping Brain Activity in vivo (2011) (970)
- Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy. (2011) (646)
- Epileptic Seizures May Begin Hours in Advance of Clinical Onset A Report of Five Patients (2001) (590)
- Race and sex differences in the distribution of cerebral atherosclerosis. (1996) (491)
- High-frequency oscillations and seizure generation in neocortical epilepsy. (2004) (482)
- Electrical Stimulation of the Anterior Nucleus of the Thalamus for the Treatment of Intractable Epilepsy (2004) (460)
- Drug discovery: A jump-start for electroceuticals (2013) (447)
- High-frequency oscillations in human temporal lobe: simultaneous microwire and clinical macroelectrode recordings. (2008) (425)
- A comparison of waveform fractal dimension algorithms (2001) (421)
- A Conformal, Bio-Interfaced Class of Silicon Electronics for Mapping Cardiac Electrophysiology (2010) (361)
- Transparent and flexible low noise graphene electrodes for simultaneous electrophysiology and neuroimaging (2014) (336)
- Bioresorbable Silicon Electronics for Transient Spatio-temporal Mapping of Electrical Activity from the Cerebral Cortex (2016) (321)
- One-Class Novelty Detection for Seizure Analysis from Intracranial EEG (2006) (304)
- Epileptic seizure prediction using hybrid feature selection over multiple intracranial EEG electrode contacts: a report of four patients (2003) (290)
- Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysis. (2006) (287)
- Microseizures and the spatiotemporal scales of human partial epilepsy. (2010) (273)
- Line length: an efficient feature for seizure onset detection (2001) (247)
- Prediction of epileptic seizures (2002) (229)
- Human and automated detection of high-frequency oscillations in clinical intracranial EEG recordings (2007) (228)
- Technology Insight: neuroengineering and epilepsy—designing devices for seizure control (2008) (221)
- Hippocampal Gamma Oscillations Increase with Memory Load (2010) (197)
- Oscillatory patterns in temporal lobe reveal context reinstatement during memory search (2011) (195)
- Modeling electroencephalography waveforms with semi-supervised deep belief nets: fast classification and anomaly measurement (2011) (186)
- Crowdsourcing reproducible seizure forecasting in human and canine epilepsy (2016) (177)
- Virtual Cortical Resection Reveals Push-Pull Network Control Preceding Seizure Evolution (2016) (167)
- Gamma Oscillations Distinguish True From False Memories (2007) (151)
- Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy (2014) (142)
- Practical detection of epileptiform discharges (EDs) in the EEG using an artificial neural network: a comparison of raw and parameterized EEG data. (1994) (138)
- Seizure prediction and the preseizure period (2002) (136)
- Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy (2015) (135)
- Unsupervised classification of high-frequency oscillations in human neocortical epilepsy and control patients. (2010) (133)
- The First International Collaborative Workshop on Seizure Prediction: summary and data description (2005) (131)
- Data mining neocortical high-frequency oscillations in epilepsy and controls. (2011) (123)
- Special issue on epileptic seizure prediction (2003) (118)
- The statistics of a practical seizure warning system (2008) (118)
- Forecasting Seizures in Dogs with Naturally Occurring Epilepsy (2014) (114)
- Automatic EEG spike detection: what should the computer imitate? (1993) (108)
- Epilepsyecosystem.org: crowd-sourcing reproducible seizure prediction with long-term human intracranial EEG (2018) (106)
- Interictal EEG spikes identify the region of electrographic seizure onset in some, but not all, pediatric epilepsy patients (2010) (104)
- A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG (2011) (99)
- Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings (2017) (97)
- Detection of seizure precursors from depth-EEG using a sign periodogram transform (2003) (96)
- Continuous energy variation during the seizure cycle: towards an on-line accumulated energy (2005) (92)
- A multi-feature and multi-channel univariate selection process for seizure prediction (2005) (92)
- Evolving a Bayesian classifier for ECG-based age classification in medical applications (2008) (88)
- Machine learning to detect signatures of disease in liquid biopsies - a user's guide. (2018) (87)
- Semi-Supervised Anomaly Detection for EEG Waveforms Using Deep Belief Nets (2010) (85)
- Evidence for self-organized criticality in human epileptic hippocampus (2002) (84)
- A high-density, high-channel count, multiplexed μECoG array for auditory-cortex recordings. (2014) (82)
- Deep brain stimulation for epilepsy (2011) (80)
- Long-range temporal correlations in epileptogenic and non-epileptogenic human hippocampus (2004) (79)
- Interictal epileptiform activity outside the seizure onset zone impacts cognition (2017) (77)
- Continuous EEG is associated with favorable hospitalization outcomes for critically ill patients (2018) (75)
- White Matter Network Architecture Guides Direct Electrical Stimulation through Optimal State Transitions (2018) (75)
- A stochastic framework for evaluating seizure prediction algorithms using hidden Markov models. (2007) (74)
- Repetitive transcranial magnetic stimulation does not replicate the Wada test (2000) (72)
- Dissolution of Monocrystalline Silicon Nanomembranes and Their Use as Encapsulation Layers and Electrical Interfaces in Water-Soluble Electronics. (2017) (71)
- Virtual resection predicts surgical outcome for drug-resistant epilepsy. (2019) (71)
- Fractal dimension characterizes seizure onset in epileptic patients (1999) (71)
- Integrating Brain Implants With Local and Distributed Computing Devices: A Next Generation Epilepsy Management System (2018) (69)
- Collaborating and sharing data in epilepsy research. (2015) (62)
- Forecasting Seizures Using Intracranial EEG Measures and SVM in Naturally Occurring Canine Epilepsy (2015) (62)
- A multimodal platform for cloud-based collaborative research (2013) (60)
- Synaptic noise and physiological coupling generate high-frequency oscillations in a hippocampal computational model. (2009) (60)
- Computational analysis in epilepsy neuroimaging: A survey of features and methods (2016) (59)
- Temporal changes of neocortical high-frequency oscillations in epilepsy. (2013) (59)
- Right-lateralized Brain Oscillations in Human Spatial Navigation (2010) (56)
- Time-frequency spectral estimation of multichannel EEG using the Auto-SLEX method (2002) (55)
- Category-specific neural oscillations predict recall organization during memory search. (2013) (55)
- Association of Piriform Cortex Resection With Surgical Outcomes in Patients With Temporal Lobe Epilepsy. (2019) (54)
- Intracranial EEG fluctuates over months after implanting electrodes in human brain (2017) (54)
- Eye closure causes widespread low-frequency power increase and focal gamma attenuation in the human electrocorticogram (2014) (53)
- Timing is everything: Where status epilepticus treatment fails (2017) (50)
- Mining continuous intracranial EEG in focal canine epilepsy: Relating interictal bursts to seizure onsets (2016) (48)
- Mapping the structural and functional network architecture of the medial temporal lobe using 7T MRI (2018) (47)
- Proceedings of the Third International Workshop on Advances in Electrocorticography (2010) (45)
- High-Frequency Oscillations Detected in Epileptic Networks Using Swarmed Neural-Network Features (2007) (41)
- Characterizing the role of the structural connectome in seizure dynamics. (2019) (40)
- Duration of EEG suppression does not predict recovery time or degree of cognitive impairment after general anaesthesia in human volunteers. (2019) (40)
- Recurring Functional Interactions Predict Network Architecture of Interictal and Ictal States in Neocortical Epilepsy (2016) (39)
- Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset. (2019) (38)
- Science in the cloud (SIC): A use case in MRI connectomics (2016) (35)
- Feasibility study of a caregiver seizure alert system in canine epilepsy (2013) (34)
- Evaluating Devices for Treating Epilepsy (2003) (31)
- High interictal connectivity within the resection zone is associated with favorable post-surgical outcomes in focal epilepsy patients (2018) (28)
- Translating seizure detection, prediction and brain stimulation into implantable devices for epilepsy (2003) (27)
- A novel seizure detection algorithm informed by hidden Markov model event states (2016) (27)
- Enabling an Open Data Ecosystem for the Neurosciences (2016) (27)
- Radiofrequency-Triggered Drug Release from Nanoliposomes with Millimeter-Scale Resolution Using a Superimposed Static Gating Field. (2018) (26)
- An open‐source automated platform for three‐dimensional visualization of subdural electrodes using CT‐MRI coregistration (2014) (26)
- Time-evolving controllability of effective connectivity networks during seizure progression (2020) (25)
- Repeated stimuli elicit diminished high-gamma electrocorticographic responses (2014) (25)
- Decoding the memorization of individual stimuli with direct human brain recordings (2013) (25)
- Lateral Transorbital Endoscopic Access to the Hippocampus, Amygdala, and Entorhinal Cortex: Initial Clinical Experience (2015) (23)
- Automatic detection of high frequency epileptiform oscillations from intracranial EEG recordings of patients with neocortical epilepsy (2005) (22)
- Vertebrobasilar dolichoectasia associated with Marfan syndrome. (2000) (22)
- Modeling the complex dynamics and changing correlations of epileptic events (2014) (22)
- A Hierarchical Dirichlet Process Model with Multiple Levels of Clustering for Human EEG Seizure Modeling (2012) (22)
- Temporal behavior of seizures and interictal bursts in prolonged intracranial recordings from epileptic canines (2016) (22)
- Network recruitment to coherent oscillations in a hippocampal computer model. (2011) (22)
- A genetic approach to selecting the optimal feature for epileptic seizure prediction (2001) (21)
- Readmission after seizure discharge in a nationally representative sample (2019) (21)
- Quantitative EEG predicts outcomes in children after cardiac arrest (2019) (20)
- Cloud computing for seizure detection in implanted neural devices (2019) (20)
- Hippocampal gamma oscillations increase with working memory load (2009) (19)
- Improved availability and quality of care with epilepsy nurse practitioners (2017) (19)
- Proceedings of the Second International Workshop on Advances in Electrocorticography (2011) (19)
- Of seizure prediction, statistics, and dogs (2007) (19)
- Bioelectronics: the promise of leveraging the body's circuitry to treat disease (2018) (18)
- Standards for data acquisition and software‐based analysis of in vivo electroencephalography recordings from animals. A TASK1‐WG5 report of the AES/ILAE Translational Task Force of the ILAE (2017) (17)
- Intracranial electroencephalography reveals two distinct similarity effects during item recognition (2009) (17)
- Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays (2018) (15)
- Brain Stimulation for Epilepsy (2001) (15)
- A Time-Frequency Functional Model for Locally Stationary Time Series Data (2009) (15)
- Logistic-weighted regression improves decoding of finger flexion from electrocorticographic signals (2014) (15)
- Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces (2018) (14)
- Electrocorticography and stereo EEG provide distinct measures of brain connectivity: implications for network models (2020) (13)
- Evolution of accumulated energy predicts seizures in mesial temporal lobe epilepsy (1999) (13)
- Millimeter-scale epileptiform spike propagation patterns and their relationship to seizures (2016) (13)
- Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale (2020) (12)
- Parsing epileptic events using a Markov switching process model for correlated time series (2013) (12)
- Epileptic Seizures May Begin Clinical Study Hours in Advance of Clinical Onset: A Report of Five Patients (2001) (12)
- Frequency and dependence of long range temporal correlations in human hippocampal energy fluctuations (2005) (12)
- Median-based filtering methods for EEG seizure detection (1999) (12)
- Fractal dimension detects seizure onset in mesial temporal lobe epilepsy (1999) (12)
- A framework For brain atlases: Lessons from seizure dynamics (2021) (11)
- Feature parameter optimization for seizure detection/prediction (2001) (11)
- Addressing barriers to surgical evaluation for patients with epilepsy (2018) (11)
- Mapping and mining interictal pathological gamma (30-100 Hz) oscillations with clinical intracranial EEG in patients with epilepsy (2012) (11)
- Model-based design for seizure control by stimulation (2020) (11)
- Local structural connectivity directs seizure spread in focal epilepsy (2018) (11)
- The sensitivity of network statistics to incomplete electrode sampling on intracranial EEG (2020) (11)
- The effect of increased intracranial EEG sampling rates in clinical practice (2018) (10)
- Advancing Neuromodulation Through Control Systems: A General Framework and Case Study in Posture‐Responsive Stimulation (2014) (10)
- Spatiotemporal evolution of focal epileptiform activity from surface and laminar field recordings in cat neocortex. (2018) (9)
- Continuous active probing and modulation of neural networks with a wireless implantable system (2017) (9)
- Normative intracranial EEG maps epileptogenic tissues in focal epilepsy. (2022) (9)
- Low‐field MRI: Clinical promise and challenges (2022) (9)
- IRIS: A Modular Platform for Continuous Monitoring and Caretaker Notification in the Intensive Care Unit (2020) (9)
- Nonparametric multi-level clustering of human epilepsy seizures (2016) (9)
- Engineering devices to treat epilepsy: a clinical perspective (2001) (8)
- Genetic Algorithm-Evolved Bayesian Network Classifier for Medical Applications (2006) (8)
- A dynamical systems framework to uncover the drivers of large-scale cortical activity (2019) (8)
- Surgical Outcomes in Post-Traumatic Epilepsy: A Single Institutional Experience. (2019) (8)
- Leaving tissue associated with infrequent intracranial EEG seizure onsets is compatible with post-operative seizure freedom (2012) (8)
- Structural analysis and design of dynamic-flow networks: Implications in the brain dynamics (2016) (8)
- Spectral control of cortical activity (2017) (8)
- Towards network-guided neuromodulation for epilepsy (2022) (7)
- Bayesian nonparametric modeling of epileptic events (2013) (7)
- Pairwise maximum entropy model explains the role of white matter structure in shaping emergent co-activation states (2021) (7)
- Big data in status epilepticus (2019) (7)
- Genetic and neuroanatomical support for functional brain network dynamics in epilepsy (2018) (7)
- White Matter Signals Reflect Information Transmission Between Brain Regions During Seizures (2021) (7)
- Brain Parcellation Aids in Electrode Localization in Epileptic Patients (2011) (6)
- Looking at Everything in Context (2015) (6)
- Flexible organic electronics for use in neural sensing (2011) (6)
- Engineering the Next Generation of Brain Scientists (2015) (6)
- Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment (2022) (6)
- Discrete gamma oscillations identify the seizure onset zone in some pediatric epilepsy patients (2011) (6)
- Seizure Prediction: Its Evolution and Therapeutic Potential (2009) (5)
- Simulated diagnostic performance of low-field MRI: Harnessing open-access datasets to evaluate novel devices (2021) (5)
- Millimeter-scale epileptiform spike patterns and their relationship to seizures (2011) (5)
- Neocortical Epilepsy and Control Patients (2010) (5)
- Proceedings of the Fourth International Workshop on Advances in Electrocorticography (2013) (5)
- Implantable devices for epilepsy: a clinical perspective (2002) (5)
- Mining terabytes of submillimeter-resolution ECoG datasets for neurophysiologic biomarkers (2010) (4)
- Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale (2021) (4)
- Theta Synchrony Is Increased near Neural Populations That Are Active When Initiating Instructed Movement (2020) (4)
- Time Evolution of the Skin–Electrode Interface Impedance under Different Skin Treatments (2021) (4)
- Computation Applied to Clinical Epilepsy and Antiepileptic Devices (2008) (4)
- A systematic approach to seizure prediction using genetic and classifier based feature selection (2002) (4)
- Dipoles and the EEG (1991) (4)
- Correction: Forecasting Seizures Using Bivariate Intracranial EEG Measures and SVM in Naturally Occurring Canine Epilepsy (2016) (3)
- Focal Seizures Induced by Intracranial Electroencephalogram Grids (2016) (3)
- Extracting seizure frequency from epilepsy clinic notes: a machine reading approach to natural language processing (2022) (3)
- An unsupervised method for identifying regions that initiate seizures on intracranial EEG (2011) (3)
- Quantitative approaches to guide epilepsy surgery from intracranial EEG. (2023) (3)
- Feature analysis of functional MRI for discrimination between normal and epileptogenic brain (2007) (3)
- How sensitive is functional connectivity to electrode resampling on intracranial EEG? Implications for personalized network models in drug-resistant epilepsy (2019) (2)
- Synchronizability predicts effective responsive neurostimulation for epilepsy prior to treatment (2021) (2)
- Quantifying Clinical Outcome Measures in Patients with Epilepsy Using the Electronic Health Record (2022) (2)
- Electrocorticography reveals spatiotemporal neuronal activation patterns of verbal fluency in patients with epilepsy (2020) (2)
- Neurophysiological Evidence for Cognitive Map Formation during Sequence Learning (2021) (2)
- Seizure Detection in Continuous Inpatient EEG (2022) (2)
- Postdiagnosis neurological care for patients with psychogenic nonepileptic spells (PNES) (2017) (2)
- Evolutionary algorithms and frequent itemset mining for analyzing epileptic oscillations (2007) (2)
- Chapter 51 – Deep Brain Stimulation for Epilepsy (2009) (2)
- Self-organized criticality in the epileptic brain (2002) (2)
- Proceedings of the second biennial Cleveland Neural Engineering Workshop 2013 (2018) (2)
- Does the morphology of high-frequency (100–500 Hz) brain oscillations change during epileptic seizures? (2011) (1)
- On the Feasibility of Natural Language Processing for Standardized Data Extraction from Electronic Medical Records of Epilepsy Patients (P1.283) (2018) (1)
- Enabling an Open Data Ecosystem for the Neurosciences (2016) (1)
- Implanting intracranial electrodes does not affect spikes or network connectivity in nearby or connected brain regions (2022) (1)
- Predicting Severity of Huntington's Disease With Wearable Sensors (2022) (1)
- Determining State of Consciousness from the Intracranial Electroencephalogram (IEEG) for Seizure Prediction (2003) (1)
- Seizure Analysis and Detection In Vivo (2009) (1)
- Synaptic Noise and Physiological Coupling Generate High Frequency Oscillations in a 4 (2009) (1)
- External drivers of BOLD signal’s non-stationarity (2021) (1)
- Engineers drive new directions in translational epilepsy research. (2022) (1)
- EEG and the anterior thalamic nucleus (2020) (1)
- A pairwise maximum entropy model uncovers the white matter scaffold underlying emergent dynamics in intracranial EEG (2018) (1)
- Quantifying trial‐by‐trial variability during cortico‐cortical evoked potential mapping of epileptogenic tissue (2023) (1)
- A Full-Stack Application for Detecting Seizures and Reducing Data During Continuous Electroencephalogram Monitoring (2021) (1)
- Deep learning-based automated segmentation of resection cavities on postsurgical epilepsy MRI (2022) (1)
- EPILEPTIFORM ACTIVITY (EA) IS COMMON IN EEGS PERFORMED FOR EVALUATION OF ACUTE ALTERATION IN MENTATION (AAM) (1999) (0)
- Pairwise maximum entropy model explains the role of white matter structure in shaping emergent co-activation states (2021) (0)
- BROCHURE & REGISTRATION NOW AVAILABLE FASD: Changing the Conversation 6 th National Biennial Conference on Adolescents and Adults with Fetal Alcohol Spectrum Disorder (2014) (0)
- Fabrication and Optimization of μECoG Electrodes and μfluidic Depth Electrode Delivery Devices (2016) (0)
- Decision letter: Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges (2021) (0)
- Title: a High-density, High-channel Count, Multiplexed Μecog Array for Auditory-cortex Recordings 1 Electrical and Systems Engineering And (2014) (0)
- Automatic Detection ofHighFrequency Epileptiform Oscillations from Intracranial EEGRecordings ofPatients withNeocortical Epilepsy (2005) (0)
- Contents Vol. 77, 2015 (2015) (0)
- Post-Diagnosis Neurological Care for Patients with Psychogenic Nonepileptic Spells (PNES) (S21.005) (2017) (0)
- Long term epilepsy outcome dynamics revealed by natural language processing of clinic notes. (2023) (0)
- To Stick or Not to Stick? Scalp and Intracranial EEG Evaluation Both Help Achieve Good Surgical and Neuropsychiatric Outcomes in Epilepsy Surgery up to 20 Years Post-Surgery (2020) (0)
- RAMSES: A full-stack application for detecting seizures and reducing data during continuous EEG monitoring (2020) (0)
- Addressing spatial bias in intracranial EEG functional connectivity analyses for epilepsy surgical planning (2022) (0)
- A Taxonomy of Seizure Spread Patterns, Speed of Spread, and Associations With Structural Connectivity (2022) (0)
- Spike patterns surrounding sleep and seizures localize the seizure‐onset zone in focal epilepsy (2022) (0)
- Real-time Processing of Multiplexed Data Acquired via Flexible Active Electrode Arrays (2011) (0)
- Single neuron computation (1993) (0)
- Clinical signatures of genetic epilepsy precede diagnosis in electronic medical records of 32,000 individuals (2022) (0)
- Spin Sample Reader. (1983) (0)
- Frequency and dependence of long range temporal correlations in human hippocampal energy fluctuations: Research Articles (2005) (0)
- Severity of illness, not EEG pattern or treatment, determine outcome in nonconvulsive status epileptics (NCSE) (1996) (0)
- Remote effects of temporal lobe epilepsy surgery: long-term morphological changes after surgical resection (2020) (0)
- Flexible biomedical devices for mapping cardiac and neural electrophysiology (2011) (0)
- Plenary speakers: Reliable interfaces with the peripheral nervous system (2013) (0)
- Live demonstration: Continuous active probing and modulation of neural networks with a wireless implantable system (2017) (0)
- A practical system for digital EEG laboratory information management (1996) (0)
- Development of a natural language processing algorithm to extract seizure types and frequencies from the electronic health record (2022) (0)
- Addressing Barriers to Surgical Evaluation for Epilepsy Patients (2018) (0)
- When Surgery Is Not Possible, All Hope Is Not Lost (2008) (0)
- Shape representation in primate visual area 4 and inferotemporal cortex (2010) (0)
- Receptive Field Properties in Auditory Cortex Cross-Correlation and Joint Spectro-Temporal (2015) (0)
- A quantitative tool for seizure severity: diagnostic and therapeutic applications (2022) (0)
- Parsing spatiotemporal dynamical stability in ECoG during seizure onset, propagation, and termination (2017) (0)
- Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces (2018) (0)
- Simulated Diagnostic Performance of Ultra-Low-Field MRI: Harnessing Open-Access Datasets to Evaluate Novel Devices (2021) (0)
- A pharmacokinetic model of anti-seizure medication load to guide care in the Epilepsy Monitoring Unit. (2023) (0)
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