Brian I. Rini
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Philosophy
Brian I. Rini's Degrees
- Bachelors Biological Sciences Stanford University
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(Suggest an Edit or Addition)Brian I. Rini's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal‐Cell Carcinoma (2018) (2700)
- Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal‐Cell Carcinoma (2019) (1808)
- Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. (2009) (1682)
- Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial (2011) (1656)
- Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. (2006) (1646)
- Avelumab plus Axitinib versus Sunitinib for Advanced Renal‐Cell Carcinoma (2019) (1425)
- Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study (2020) (1264)
- Sunitinib in patients with metastatic renal cell carcinoma. (2006) (965)
- Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma. (2015) (934)
- Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial. (2015) (926)
- Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients (2009) (832)
- Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. (2010) (759)
- Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma (2018) (750)
- External validation and comparison with other models of the International Metastatic Renal-Cell Carcinoma Database Consortium prognostic model: a population-based study. (2013) (723)
- Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial. (2016) (703)
- Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. (2008) (687)
- Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial. (2013) (636)
- Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial (2019) (611)
- Hypertension as a Biomarker of Efficacy in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib (2011) (570)
- Resistance to targeted therapy in renal-cell carcinoma. (2009) (517)
- Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583). (2004) (512)
- Renal cell carcinoma (2009) (498)
- Sunitinib Reverses Type-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients (2008) (479)
- Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial. (2019) (473)
- Treatment of renal cell carcinoma: Current status and future directions (2017) (472)
- Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study. (2007) (433)
- Renal cell carcinoma (2007) (419)
- Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma. (2005) (404)
- Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. (2010) (403)
- A Pilot Trial of CTLA-4 Blockade with Human Anti-CTLA-4 in Patients with Hormone-Refractory Prostate Cancer (2007) (396)
- Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. (2008) (395)
- Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma. (2013) (394)
- Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity. (2015) (387)
- Cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium. (2014) (379)
- Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. (2007) (378)
- Safety and Efficacy of Nivolumab in Combination With Ipilimumab in Metastatic Renal Cell Carcinoma: The CheckMate 016 Study. (2017) (334)
- Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma. (2009) (328)
- The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy. (2011) (328)
- Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins (2007) (321)
- Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. (2008) (313)
- Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma. (2011) (303)
- The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study. (2015) (286)
- Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. (2010) (284)
- Pembrolizumab plus axitinib versus sunitinib monotherapy as first-line treatment of advanced renal cell carcinoma (KEYNOTE-426): extended follow-up from a randomised, open-label, phase 3 trial. (2020) (276)
- Randomized Phase III Trial of Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma. (2017) (261)
- MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. (2011) (258)
- Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with sunitinib or pazopanib in patients (pts) with metastatic renal cell carcinoma (mRCC). (2014) (253)
- Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF. (2009) (252)
- CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion. (2008) (237)
- Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 4-year follow-up of the phase III CheckMate 214 trial (2020) (234)
- Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial. (2013) (230)
- Clinical factors associated with outcome in patients with metastatic clear‐cell renal cell carcinoma treated with vascular endothelial growth factor‐targeted therapy (2007) (225)
- HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism (2017) (224)
- Morphology, Attenuation, Size, and Structure (MASS) criteria: assessing response and predicting clinical outcome in metastatic renal cell carcinoma on antiangiogenic targeted therapy. (2010) (218)
- A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies. (2015) (215)
- Impact of bone and liver metastases on patients with renal cell carcinoma treated with targeted therapy. (2014) (202)
- Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial. (2014) (202)
- Preliminary results for avelumab plus axitinib as first-line therapy in patients with advanced clear-cell renal-cell carcinoma (JAVELIN Renal 100): an open-label, dose-finding and dose-expansion, phase 1b trial. (2018) (201)
- Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma. (2017) (194)
- IMmotion151: A Randomized Phase III Study of Atezolizumab Plus Bevacizumab vs Sunitinib in Untreated Metastatic Renal Cell Carcinoma (mRCC) (2018) (189)
- Metastatic non–clear cell renal cell carcinoma treated with targeted therapy agents: Characterization of survival outcome and application of the International mRCC Database Consortium criteria (2013) (182)
- Diastolic Blood Pressure as a Biomarker of Axitinib Efficacy in Solid Tumors (2011) (179)
- Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium (2021) (178)
- Response of the primary tumor to neoadjuvant sunitinib in patients with advanced renal cell carcinoma. (2009) (178)
- Active surveillance in metastatic renal-cell carcinoma: a prospective, phase 2 trial. (2016) (176)
- Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. (2009) (175)
- HIF Inhibitors: Status of Current Clinical Development (2019) (174)
- Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade. (2020) (173)
- Phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC). (2014) (171)
- Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma (2016) (169)
- Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results. (2002) (168)
- Renal Angiomyolipoma: Clinicopathologic Study of 194 Cases With Emphasis on the Epithelioid Histology and Tuberous Sclerosis Association (2009) (167)
- Recent Progress in the Management of Advanced Renal Cell Carcinoma (2007) (165)
- AG-013736, a multi-target tyrosine kinase receptor inhibitor, demonstrates anti-tumor activity in a Phase 2 study of cytokine-refractory, metastatic renal cell cancer (RCC) (2005) (163)
- Phase 1 dose‐escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma (2011) (162)
- COVID-19 and Cancer: Current Challenges and Perspectives (2020) (160)
- Vascular Endothelial Growth Factor–Targeted Therapy in Renal Cell Carcinoma: Current Status and Future Directions (2007) (159)
- von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. (2008) (159)
- Patient-reported outcomes of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib (CheckMate 214): a randomised, phase 3 trial. (2019) (158)
- The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of advanced renal cell carcinoma (RCC) (2019) (158)
- Safety and Efficacy of Nivolumab in Patients With Metastatic Renal Cell Carcinoma Treated Beyond Progression: A Subgroup Analysis of a Randomized Clinical Trial. (2016) (156)
- Temsirolimus, an Inhibitor of Mammalian Target of Rapamycin (2008) (152)
- Phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil in patients with metastatic renal cell cancer. (2000) (150)
- IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial. (2016) (150)
- Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations. (2016) (148)
- Cancer and Leukemia Group B 90206 (2004) (147)
- State of the Science: An Update on Renal Cell Carcinoma (2012) (146)
- Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy. (2008) (144)
- Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study (2018) (141)
- Sunitinib facilitates the activation and recruitment of therapeutic anti‐tumor immunity in concert with specific vaccination (2011) (140)
- Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma (2018) (140)
- The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C (2012) (136)
- Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy. (2016) (135)
- Surgical resection of renal cell carcinoma after targeted therapy. (2009) (130)
- Prognostic factors for survival in 1059 patients treated with sunitinib for metastatic renal cell carcinoma (2013) (130)
- Survival outcomes and independent response assessment with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma: 42-month follow-up of a randomized phase 3 clinical trial (2020) (130)
- Combination immunotherapy with prostatic acid phosphatase pulsed antigen‐presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy (2006) (129)
- Axitinib in Metastatic Renal Cell Carcinoma: Results of a Pharmacokinetic and Pharmacodynamic Analysis (2013) (128)
- Sunitinib rechallenge in metastatic renal cell carcinoma patients (2010) (128)
- ICUD-EAU International Consultation on Kidney Cancer 2010: treatment of metastatic disease. (2011) (127)
- Angiogenesis and the tumor microenvironment: vascular endothelial growth factor and beyond. (2014) (126)
- Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib (2012) (126)
- Phase 2 trials of SU11248 show antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma (RCC) (2005) (124)
- Outcomes of patients with metastatic renal cell carcinoma that do not meet eligibility criteria for clinical trials. (2014) (122)
- Metastatic renal cell carcinoma: many treatment options, one patient. (2009) (122)
- The immunology of renal cell carcinoma (2020) (121)
- A high rate of venous thromboembolism in a multi‐institutional Phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil and daily thalidomide in patients with metastatic renal cell carcinoma (2002) (117)
- Metastasectomy after targeted therapy in patients with advanced renal cell carcinoma. (2011) (117)
- Myeloid-Derived Suppressor Cell Subset Accumulation in Renal Cell Carcinoma Parenchyma Is Associated with Intratumoral Expression of IL1β, IL8, CXCL5, and Mip-1α (2016) (116)
- Tivozanib versus sorafenib in patients with advanced renal cell carcinoma (TIVO-3): a phase 3, multicentre, randomised, controlled, open-label study. (2019) (114)
- A 2 weeks on and 1 week off schedule of sunitinib is associated with decreased toxicity in metastatic renal cell carcinoma. (2014) (113)
- Conditional survival of patients with metastatic renal-cell carcinoma treated with VEGF-targeted therapy: a population-based study. (2012) (111)
- Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma (2020) (109)
- Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study (2020) (107)
- Clinical response to therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: impact of patient characteristics and Von Hippel‐Lindau gene status (2006) (107)
- AMG 386 in combination with sorafenib in patients with metastatic clear cell carcinoma of the kidney (2012) (106)
- Axitinib versus sorafenib in advanced renal cell carcinoma: subanalyses by prior therapy from a randomised phase III trial (2014) (102)
- Prostate-specific antigen kinetics as a measure of the biologic effect of granulocyte-macrophage colony-stimulating factor in patients with serologic progression of prostate cancer. (2003) (97)
- Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial. (2011) (92)
- Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer. (2004) (91)
- CheckMate 214: Efficacy and safety of nivolumab + ipilimumab (N+I) v sunitinib (S) for treatment-naïve advanced or metastatic renal cell carcinoma (mRCC), including IMDC risk and PD-L1 expression subgroups (2017) (90)
- Association of diastolic blood pressure (dBP) ≥ 90 mmHg with overall survival (OS) in patients treated with axitinib (AG- 013736). (2008) (87)
- A Phase I Study of Sunitinib plus Bevacizumab in Advanced Solid Tumors (2009) (87)
- New Strategies in Kidney Cancer: Therapeutic Advances through Understanding the Molecular Basis of Response and Resistance (2010) (86)
- Sunitinib-associated hypertension and neutropenia as efficacy biomarkers in metastatic renal cell carcinoma patients (2015) (84)
- Axitinib (AG-013736; AG) in patients (pts) with metastatic renal cell cancer (RCC) refractory to sorafenib (2007) (83)
- Vascular endothelial growth factor‐targeted therapy in metastatic renal cell carcinoma (2009) (83)
- Pembrolizumab (pembro) plus axitinib (axi) versus sunitinib as first-line therapy for metastatic renal cell carcinoma (mRCC): Outcomes in the combined IMDC intermediate/poor risk and sarcomatoid subgroups of the phase 3 KEYNOTE-426 study. (2019) (82)
- The effect of sunitinib on primary renal cell carcinoma and facilitation of subsequent surgery. (2012) (81)
- Adenosine A2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer. (2019) (81)
- Prospective Clinical Study of Precision Oncology in Solid Tumors. (2015) (81)
- Progression‐free survival as a predictor of overall survival in metastatic renal cell carcinoma treated with contemporary targeted therapy (2011) (81)
- The evolving role of surgery for advanced renal cell carcinoma in the era of molecular targeted therapy. (2007) (79)
- Outcome of patients with metastatic sarcomatoid renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium. (2015) (79)
- Randomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma. (2016) (79)
- SU011248, a novel tyrosine kinase inhibitor, shows antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma: Results of a phase 2 trial. (2004) (79)
- HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma (2019) (78)
- A multicenter prospective trial of sorafenib in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab (2008) (77)
- Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages (2021) (77)
- Successful implementation of the randomized discontinuation trial design: an application to the study of the putative antiangiogenic agent carboxyaminoimidazole in renal cell carcinoma--CALGB 69901. (2005) (76)
- CheckMate 214 post-hoc analyses of nivolumab plus ipilimumab or sunitinib in IMDC intermediate/poor-risk patients with previously untreated advanced renal cell carcinoma with sarcomatoid features. (2019) (76)
- Expanded cohort results from CheckMate 016: A phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC). (2015) (75)
- Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer (2019) (75)
- Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy. (2010) (75)
- A Phase II Study of Pazopanib in Patients with Localized Renal Cell Carcinoma to Optimize Preservation of Renal Parenchyma. (2015) (75)
- Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial (2020) (74)
- The impact of low serum sodium on treatment outcome of targeted therapy in metastatic renal cell carcinoma: results from the International Metastatic Renal Cell Cancer Database Consortium. (2014) (74)
- Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma. (2008) (74)
- Adult Cystic Nephroma and Mixed Epithelial and Stromal Tumor of the Kidney Are the Same Disease Entity: Molecular and Histologic Evidence (2009) (73)
- Survival outcome and treatment response of patients with late relapse from renal cell carcinoma in the era of targeted therapy. (2014) (72)
- Erratum: Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial (Lancet (2011) 378 (1931-39)) (2012) (72)
- Prostate cancer update (2002) (72)
- Axitinib dose titration: analyses of exposure, blood pressure and clinical response from a randomized phase II study in metastatic renal cell carcinoma. (2015) (72)
- Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma (2014) (71)
- CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma. (2015) (71)
- A phase II study of atezolizumab (atezo) with or without bevacizumab (bev) versus sunitinib (sun) in untreated metastatic renal cell carcinoma (mRCC) patients (pts). (2017) (71)
- Sunitinib in metastatic renal cell carcinoma (mRCC): Preliminary assessment of toxicity in an expanded access trial with subpopulation analysis (2007) (68)
- Molecular correlates differentiate response to atezolizumab (atezo) + bevacizumab (bev) vs sunitinib (sun): Results from a phase III study (IMmotion151) in untreated metastatic renal cell carcinoma (mRCC). (2018) (68)
- Hydroxychloroquine as Pre-exposure Prophylaxis for Coronavirus Disease 2019 (COVID-19) in Healthcare Workers: A Randomized Trial (2020) (67)
- VEGF-targeted therapy in metastatic renal cell carcinoma. (2005) (67)
- Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab (2010) (67)
- Prognostic factors of survival for patients with metastatic renal cell carcinoma with brain metastases treated with targeted therapy: results from the international metastatic renal cell carcinoma database consortium. (2013) (67)
- Nivolumab for metastatic renal cell carcinoma (mRCC): Results of a randomized, dose-ranging phase II trial. (2014) (66)
- Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of renal cell carcinoma (2016) (66)
- A population‐based study evaluating the impact of sunitinib on overall survival in the treatment of patients with metastatic renal cell cancer (2009) (66)
- Hormone-Refractory prostate cancer (2002) (66)
- First-, second-, third-line therapy for mRCC: benchmarks for trial design from the IMDC (2014) (65)
- Metabolism of kidney cancer: from the lab to clinical practice. (2013) (64)
- Third-line Targeted Therapy in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium. (2017) (64)
- IMmotion150: A phase II trial in untreated metastatic renal cell carcinoma (mRCC) patients (pts) of atezolizumab (atezo) and bevacizumab (bev) vs and following atezo or sunitinib (sun). (2017) (63)
- Molecular Biomarkers in Advanced Renal Cell Carcinoma (2014) (62)
- A phase II study of gemcitabine and capecitabine in metastatic renal cancer (2006) (62)
- Maximal COX‐2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma (2006) (62)
- Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: phase III (AXIS) trial (2013) (61)
- First-line sunitinib versus pazopanib in metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium. (2016) (61)
- Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer. (2005) (61)
- Renal cell carcinoma (2005) (60)
- Association of percentage of tumour burden removed with debulking nephrectomy and progression‐free survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor‐targeted therapy (2010) (60)
- A phase II trial of imatinib mesylate in patients with biochemical relapse of prostate cancer after definitive local therapy (2006) (60)
- Efficacy and safety of sunitinib malate (SU11248) in bevacizumab-refractory metastatic renal cell carcinoma (mRCC). (2006) (60)
- Thirty-month follow-up of the phase III CheckMate 214 trial of first-line nivolumab + ipilimumab (N+I) or sunitinib (S) in patients (pts) with advanced renal cell carcinoma (aRCC). (2019) (59)
- Clinical trial experience with temsirolimus in patients with advanced renal cell carcinoma. (2009) (59)
- Emerging Role of Combination Immunotherapy in the First-line Treatment of Advanced Renal Cell Carcinoma: A Review (2019) (58)
- Sequencing of agents for metastatic renal cell carcinoma: can we customize therapy? (2012) (58)
- Targeted molecular therapy for renal cell carcinoma. (2007) (58)
- Safety and clinical activity of vascular endothelial growth factor receptor (VEGFR)-tyrosine kinase inhibitors after programmed cell death 1 inhibitor treatment in patients with metastatic clear cell renal cell carcinoma. (2016) (57)
- Long-term Safety of Sunitinib in Metastatic Renal Cell Carcinoma. (2016) (56)
- Atezolizumab plus Bevacizumab Versus Sunitinib for Patients with Untreated Metastatic Renal Cell Carcinoma and Sarcomatoid Features: A Prespecified Subgroup Analysis of the IMmotion151 Clinical Trial. (2020) (55)
- From Basic Science to Clinical Translation in Kidney Cancer: A Report from the Second Kidney Cancer Research Summit. (2021) (55)
- Individualised axitinib regimen for patients with metastatic renal cell carcinoma after treatment with checkpoint inhibitors: a multicentre, single-arm, phase 2 study. (2019) (54)
- Phase II study of lenalidomide in patients with metastatic renal cell carcinoma (2006) (54)
- GD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells. (2009) (54)
- Castration‐resistant prostate cancer: Many treatments, many options, many challenges ahead (2012) (53)
- Novel agents in renal carcinoma: a reality check (2012) (53)
- Therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: biology, clinical results and future development (2005) (53)
- Patterns, predictors and subsequent outcomes of disease progression in metastatic renal cell carcinoma patients treated with nivolumab (2018) (52)
- Pembrolizumab (pembro) plus axitinib (axi) versus sunitinib as first-line therapy for advanced clear cell renal cell carcinoma (ccRCC): Results from 42-month follow-up of KEYNOTE-426. (2021) (52)
- Overall survival and independent review of response in CheckMate 214 with 42-month follow-up: First-line nivolumab + ipilimumab (N+I) versus sunitinib (S) in patients (pts) with advanced renal cell carcinoma (aRCC). (2020) (51)
- Long-term overall survival (OS) with nivolumab in previously treated patients with advanced renal cell carcinoma (aRCC) from phase I and II studies. (2016) (50)
- Diastolic blood pressure (dBP) and pharmacokinetics (PK) as predictors of axitinib efficacy in metastatic renal cell cancer (mRCC). (2009) (50)
- Elevated Levels of Select Gangliosides in T Cells from Renal Cell Carcinoma Patients Is Associated with T Cell Dysfunction1 (2009) (50)
- Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma (2013) (50)
- Presurgical sunitinib reduces tumor size and may facilitate partial nephrectomy in patients with renal cell carcinoma. (2015) (50)
- Vascular endothelial growth factor-targeted therapies in advanced renal cell carcinoma. (2011) (49)
- COVID-19 and immune checkpoint inhibitors: initial considerations (2020) (49)
- Checkpoint inhibitors in patients with metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium (2018) (49)
- CheckMate 214: A phase III, randomized, open-label study of nivolumab combined with ipilimumab versus sunitinib monotherapy in patients with previously untreated metastatic renal cell carcinoma. (2015) (48)
- Five-year survival in patients with cytokine-refractory metastatic renal cell carcinoma treated with axitinib. (2013) (48)
- p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies. (2012) (48)
- Tumor Necrosis Adds Prognostically Significant Information to Grade in Clear Cell Renal Cell Carcinoma: A Study of 842 Consecutive Cases From a Single Institution (2016) (47)
- Hypertension among patients with renal cell carcinoma receiving axitinib or sorafenib: analysis from the randomized phase III AXIS trial (2014) (47)
- Prognostic factors in renal carcinoma. (2000) (46)
- Pancreatic tropism of metastatic renal cell carcinoma. (2020) (46)
- The association of clinical outcome to first-line VEGF-targeted therapy with clinical outcome to second-line VEGF-targeted therapy in metastatic renal cell carcinoma patients (2013) (46)
- Pembrolizumab plus axitinib versus sunitinib as first-line therapy for advanced renal cell carcinoma (RCC): Updated analysis of KEYNOTE-426. (2020) (46)
- Alternate sunitinib schedules in patients with metastatic renal cell carcinoma. (2015) (45)
- Neoadjuvant therapy for localized and locally advanced renal cell carcinoma. (2018) (45)
- Validation of the 16-Gene Recurrence Score in Patients with Locoregional, High-Risk Renal Cell Carcinoma from a Phase III Trial of Adjuvant Sunitinib (2018) (44)
- Conditional survival and long‐term efficacy with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma (2022) (44)
- Phase II trial of sunitinib in bevacizumab-refractory metastatic renal cell carcinoma (mRCC): Updated results and analysis of circulating biomarkers (2007) (44)
- Technology evaluation: APC-8015, Dendreon. (2002) (44)
- Phase I study of direct intralesional gene transfer of HLA-B7 into metastatic renal carcinoma lesions. (1999) (43)
- Sequencing and Combination of Systemic Therapy in Metastatic Renal Cell Carcinoma. (2019) (43)
- Salvage Ipilimumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma After Prior Immune Checkpoint Inhibitors. (2020) (43)
- Renal cell carcinoma (2006) (43)
- Management of side effects associated with sunitinib therapy for patients with renal cell carcinoma (2009) (43)
- Prostate cancer immunology: biology, therapeutics, and challenges. (2005) (42)
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- Care without a compass: Including patients with cancer in COVID-19 studies (2021) (12)
- Myeloid-Derived Suppressor Cell Subset Accumulation in Renal Cell Carcinoma Parenchyma Is Associated with Intratumoral Expression of IL1b, IL8, CXCL5, and Mip-1a (2017) (12)
- Drug Holiday in Metastatic Renal‐Cell Carcinoma Patients Treated With Vascular Endothelial Growth Factor Receptor Inhibitors (2018) (11)
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- Abstract CT081: Molecular correlates of differential response to Atezolizumab +/- Bevacizumab vs Sunitnib in a Phase II study in untreated metastatic renal cell carcinoma (RCC) patients (2017) (11)
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- Systemic therapy for advanced clear cell renal cell carcinoma after discontinuation of immune-oncology and VEGF targeted therapy combinations (2020) (11)
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- The ineligible patient: how to treat patients not included in clinical studies (2014) (9)
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- Sunitinib (2007) (9)
- The HLA‐A2‐restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer (2009) (9)
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- Pembrolizumab plus axitinib versus sunitinib in metastatic renal cell carcinoma: outcomes of Japanese patients enrolled in the randomized, phase III, open-label KEYNOTE-426 study (2021) (9)
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- Axitinib in Metastatic Renal Cell Carcinoma (2012) (8)
- A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma (2018) (8)
- Health-related Quality of Life Analysis from KEYNOTE-426: Pembrolizumab plus Axitinib Versus Sunitinib for Advanced Renal Cell Carcinoma. (2022) (8)
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- Myeloid-Derived Suppressor Cells in Nonmetastatic Urothelial Carcinoma of Bladder Is Associated With Pathologic Complete Response and Overall Survival. (2020) (8)
- Contrast enhanced CT (CE-CT) changes and nephrometry down-scoring of unresectable primary renal cell carcinoma (RCC) tumors in patients (Pts) treated with neoadjuvant sunitinib. (2011) (8)
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- Erratum: Pazopanib for the treatment of renal cancer (Expert Opin Pharmacother (2011) 12: 7 (1171-1189)) (2011) (7)
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- Ipilimumab plus nivolumab (Ipi/Nivo) as salvage therapy in patients with immunotherapy (IO)-refractory metastatic renal cell carcinoma (mRCC). (2019) (7)
- Association of neutrophil to lymphocyte ratio (NLR) with efficacy from JAVELIN Renal 101. (2020) (7)
- Sorafenib (2006) (6)
- GM 1 and Tumor Necrosis Factor-A , Overexpressed in Renal Cell Carcinoma , Synergize to Induce T-Cell Apoptosis (2008) (6)
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- Hereditary implications of somatic tumor testing. (2015) (6)
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- Holland - Frei Manual Of Cancer Medicine (2005) (5)
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- Efficacy and safety of nivolumab plus ipilimumab (N+I) versus sunitinib (S) for first-line treatment of patients with advanced sarcomatoid renal cell carcinoma (sRCC) in the phase 3 CheckMate 214 trial with extended 5-year minimum follow-up. (2022) (4)
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- Radical shifts in the first-line management of metastatic renal cell carcinoma (2018) (4)
- Long term toxicity of tyrosine kinase inhibitors (TKIs) in patients with metastatic clear cell renal cell carcinoma (RCC) (2008) (4)
- 3006 POSTER DISCUSSION Time to Deterioration (TTD) in Patient-reported Outcomes in Phase 3 AXis Trial of Axitinib Vs Sorafenib as Second-line Therapy for Metastatic Renal Cell Carcinoma (mRCC) (2011) (4)
- Sunitinib's effect on tumor infiltration of CD8 T cells in renal cell carcinoma (RCC) and modulation of their function by altering VEGF-induced upregulation of PD1 expression. (2016) (4)
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- Outcomes in Black and White Patients With Metastatic Renal Cell Carcinoma Treated With First-Line Tyrosine Kinase Inhibitors: Insights From Two Large Cohorts (2020) (4)
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- 4510 POSTER A phase 2 trial of sunitinib in bevacizumab-refractory metastatic renal cell carcinoma (mRCC): updated results and analysis of circulating biomarkers (2007) (4)
- Role of VEGF and VEGFR2 single nucleotide polymorphisms (SNPs) in predicting treatment-induced hypertension (HTN) and clinical outcome (CO) in metastatic clear cell RCC (mccRCC) patients (pts) treated with sunitinib. (2010) (4)
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- Kidney cancer: Does hypothyroidism predict clinical outcome? (2011) (4)
- Pharmacokinetically Guided Dosing of Oral Drugs: True Precision Oncology? (2016) (4)
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- Immune cell changes in the peripheral blood of metastatic renal cell carcinoma (mRCC) patients (pts) treated with sunitinib or temsirolimus (2008) (3)
- What is standard initial systemic therapy in metastatic renal cell carcinoma? (2007) (3)
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- A multicenter retrospective study to evaluate real-world clinical outcomes in patients with metastatic renal cell carcinoma (mRCC) and brain metastasis treated with ipilimumab and nivolumab. (2020) (2)
- Association between prior nephrectomy and efficacy of immune checkpoint inhibitor therapy in metastatic renal cell carcinoma - A systematic review and meta-analysis. (2021) (2)
- Long-term follow up after non-myeloablative allogeneic stem cell transplantation for renal cell carcinoma: the university of Chicago experience (2004) (2)
- Discrepancy between reported progressive disease per radiology report and treating oncologist tumor measurements in patients with metastatic renal cell carcinoma (mRCC) receiving sunitinib. (2012) (2)
- First-in-human study of SRF388, a first-in-class IL-27 targeting antibody, as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors. (2022) (2)
- Can patient-reported kidney cancer–specific symptoms at baseline serve as an indicator for median progression-free and overall survival in sorafenib-refractory metastatic renal cell carcinoma? (2010) (2)
- An observational study of metastatic renal cell carcinoma patients prior to initiation of initial systemic therapy. (2012) (2)
- Professional practice gaps and barriers to optimal care of renal cell carcinoma (RCC) among oncologists in the United States. (2014) (2)
- Long-term PFS from TIVO-3: Tivozanib (TIVO) versus sorafenib (SOR) in relapsed/refractory (R/R) advanced RCC. (2022) (2)
- Assessment of blood and tissue myeloid derived suppressor cells (MDSC), clinicopathologic factors, and treatment response in urothelial carcinoma (UC) patients (pts) undergoing surgery. (2017) (2)
- Progression‐free survival: Does a correlation with survival justify its role as a surrogate clinical endpoint? (2015) (2)
- Quality of life in patients with advanced renal cell carcinoma in the randomized, open-label CheckMate 214 trial. (2018) (2)
- 417 Phase 3 study of pembrolizumab + belzutifan + lenvatinib or pembrolizumab/quavonlimab + lenvatinib versus pembrolizumab + lenvatinib as first-line treatment for advanced renal cell carcinoma (2021) (2)
- Patient-reported outcomes (PROs) in IMmotion150: Atezolizumab (atezo) alone or with bevacizumab (bev) versus sunitinib (sun) in first-line metastatic renal cell carcinoma (mRCC). (2019) (2)
- Clinical activity of abiraterone acetate in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. (2014) (2)
- 7154 An International Expanded Access Program (EAP) of RAD001 (everolimus) in patients with metastatic renal cell carcinoma (mRCC) who fail, or become intolerant of a prior vascular endothelial growth factor receptor (VEGFr) therapy (2009) (2)
- Circulating tumor cell kinetics in mRCC patients treated with sunitinib (2014) (2)
- HSD3B1 genotype and abiraterone (Abi) metabolites in patients (pts) with prostate cancer (PCa). (2018) (2)
- TIVO-3: Tivozanib in patients with advanced renal cell carcinoma (aRCC) who have progressed after treatment with axitinib. (2021) (2)
- Treatment of Refractory Metastatic Renal Cell Carcinoma (2022) (2)
- Identifying Prostate Surface Antigen Patterns of Change in Patients with Metastatic Hormone Sensitive Prostate Cancer Treated with Abiraterone and Prednisone (2020) (2)
- Comprar Renal Cell Carcinoma | Brian I. Rini | 9781607950035 | Mcgraw-Hill Education (2009) (2)
- 669P Subsequent therapy following pembrolizumab + axitinib or sunitinib treatment for advanced renal cell carcinoma (RCC) in the phase III KEYNOTE-426 study (2021) (2)
- First-line mTOR inhibition in metastatic renal cell carcinoma (mRCC): An updated analysis from the International mRCC Database Consortium (IMDC). (2013) (2)
- Lapatinib therapy for patients with advanced renal cell carcinoma (2008) (2)
- Molecularly targeted therapy in renal cell carcinoma: where do we go from here? (2006) (2)
- Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma (2022) (2)
- Clinic and Home Blood Pressure Measurements are Reliable for Guiding Therapy in Patients with Metastatic Renal Cell Carcinoma Receiving Axitinib as First-Line Therapy (2012) (2)
- Malignant angiomyolipoma: a rare entity with unusual biology. (2011) (2)
- What Is Standard Initials Systemic Therapy in Metastatic Renal Cell Carcinoma (2007) (2)
- What are the prognostic factors for survival in patients with metastatic renal cell carcinoma? (2005) (2)
- A phase Ib trial of neoadjuvant/adjuvant durvalumab +/- tremelimumab in locally advanced renal cell carcinoma (RCC). (2020) (2)
- TIVO-3: Durability of response and updated overall survival of tivozanib versus sorafenib in metastatic renal cell carcinoma (mRCC). (2021) (2)
- The Evolution of Systemic Therapy in Metastatic Renal Cell Carcinoma. (2016) (2)
- DART Study: A phase II randomized trial of dalantercept plus axitinib versus placebo plus axitinib in advanced clear cell renal cell carcinoma (RCC): Results from Part 1. (2015) (2)
- 354 Phase I study of investigational oral mTORC1/2 inhibitor MLN0128: Expansion phase in patients with renal, endometrial, or bladder cancer (2015) (2)
- The role of stereotactic radiosurgery in the treatment of renal cell carcinoma patients with five or more brain metastases. (2012) (2)
- Adjuvant enzalutamide (Enza) for men with non-metastatic high-risk prostate cancer (HRPCa) after radical prostatectomy (RP). (2018) (2)
- Discontinuing VEGF-targeted therapy (VEGF-TT) for progression versus toxicity impacts outcomes of second-line therapies in metastatic renal cell carcinoma (mRCC). (2016) (2)
- 502: Effect of Sunitinib in Patients with Unresectable Primary Renal Cell Carcinoma (2007) (2)
- Outcomes of patients who progressed while receiving avelumab + axitinib (A + Ax) and received subsequent treatment (Tx) in JAVELIN Renal 101. (2021) (2)
- Update on the use of mTOR inhibitors in renal cell carcinoma. (2008) (2)
- A phase III study of atezolizumab vs placebo as adjuvant therapy in patients with renal cell carcinoma at high risk of recurrence following resection (IMmotion010) (2018) (2)
- Prognostic value of DLL3 expression and clinicopathologic features in small cell bladder cancer (SCBC). (2017) (2)
- Overall survival results from the phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma (METEOR) (2017) (1)
- Biomarkers of response to VEGF pathway-targeted therapy for renal cell carcinoma. (2006) (1)
- Association of baseline neutrophil-to-eosinophil ratio (NER) and neutrophil-to-lymphocyte ratio (NLR) with response to combination immunotherapy (IO) with ipilimumab plus nivolumab (ipi/nivo) in patients with metastatic renal cell carcinoma (mRCC). (2021) (1)
- Renal cell carcinoma. (2007) (1)
- Temporal characteristics of treatment-emergent adverse events and dose modifications with tivozanib and sorafenib in the phase 3 TIVO-3 study of relapsed or refractory mRCC. (2021) (1)
- Cisplatin-based neoadjuvant chemotherapy (NAC) in bladder cancer patients (Pts) with borderline renal function: Implications for clinical practice. (2017) (1)
- Are immune checkpoint combination therapies for intermediate and poor risk renal cell carcinoma better than immune checkpoint inhibitors combined with kinase inhibitors? (2021) (1)
- An alternative titration schedule of axitinib in metastatic renal cell carcinoma. (2015) (1)
- The role of stereotactic radiosurgery in the treatment of renal cell carcinoma patients with five or more brain metastases. (2012) (1)
- Adjuvant enzalutamide (Enza) for men with high-risk prostate cancer (HRPCa) after radical prostatectomy (RP). (2016) (1)
- Erratum (2011) (1)
- 4LBA Cabozantinib versus everolimus in patients with advanced renal cell carcinoma: Results of the randomized phase 3 METEOR trial (2015) (1)
- Characteristics of long-term and short-term survivors of metastatic renal cell carcinoma (mRCC) treated with targeted therapy: Results from the International mRCC Database Consortium. (2012) (1)
- A phase I/II study of lenalidomide in combination with sunitinib in patients with advanced or metastatic renal cell carcinoma. (2014) (1)
- Angiogenic and immunomodulatory biomarkers in axitinib-treated patients (pts) with advanced renal cell carcinoma (aRCC). (2019) (1)
- Clinical effect of TKI dose-escalation after disease progression in patients with metastatic renal cell carcinoma. (2015) (1)
- Unraveling the molecular profile underpinning pancreatic tropisms in metastatic clear cell renal cell carcinoma. (2019) (1)
- Practice challenges affecting optimal care as identifed by US medical oncologists who treat renal cell carcinomas. (2014) (1)
- Cessation of VEGF-targeted therapy in patients with metastatic renal cell carcinoma (mRCC): Feasibility and clinical outcome. (2011) (1)
- Prior estrogen therapy as a predictor of response to subsequent estramustine-based therapy in androgen-independent prostate cancer patients. (2004) (1)
- Unclassified renal cell carcinoma (RCC): Analysis of clinical and pathologic features (2008) (1)
- PIVOT IO 011: A phase 1/2 study of bempegaldesleukin (BEMPEG; NKTR-214) plus nivolumab (NIVO) and tyrosine kinase inhibitor (TKI) versus NIVO and TKI alone in patients (pts) with previously untreated advanced or metastatic renal cell carcinoma (mRCC). (2022) (1)
- Assessment of sarcopenia as predictor of response and outcome after neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) in muscle-invasive bladder cancer (MIBC). (2015) (1)
- Association of on-treatment plasma HGF levels with overall survival (OS) in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (INF) +/- bevacizumab (BEV): Results from CALGB 90206 (Alliance). (2017) (1)
- Response: Re: Hypertension as a Biomarker of Efficacy in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib (2011) (1)
- Abstract 630: Interleukin-8 as a potential mediator for renal cell carcinoma resistance to antiangiogenic sunitinib therapy (2010) (1)
- Response: Re: Hypothyroidism in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib (2007) (1)
- Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia? (2015) (1)
- Phase II study of alternate sunitinib schedule in patients with metastatic renal cell carinoma. (2017) (1)
- SUNITINIB MALATE (SU11248) – EFFICACY IN RENAL CELL CARCINOMA (RCC) (2006) (1)
- Outcomes of metastatic chromophobe renal cell carcinoma (chrRCC) in the targeted therapy era: Results from the International Metastatic Renal Cell Cancer Database Consortium. (2016) (1)
- The mechanism of action and resistance of sunitinib in RCC. (2010) (1)
- Macrocytosis in patients with metastatic renal cell carcinoma (mRCC) treated with tyrosine kinase inhibitors (TKI's) (2007) (1)
- A phase II study of alternative sunitinib scheduling in patients with metastatic renal cell carcinoma. (2017) (1)
- Prognostic and predictive tumor-based biomarkers in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (IFN) with or without bevacizumab (Bev): Results from CALGB (Alliance) 90206. (2014) (1)
- Extended therapy breaks from VEGFR TKI therapy in renal cell carcinoma: Sometimes less is more (2017) (1)
- First-, second-, third-line therapy for metastatic renal cell carcinoma (mRCC): Benchmarks for trials design from the International mRCC Database Consortium (IMDC). (2013) (1)
- A population-based overview of sequences of targeted therapy in metastatic renal cell carcinoma (mRCC). (2012) (1)
- Robotic partial nephrectomy after pazopanib treatment in a solitary kidney with segmental vein thrombosis (2019) (1)
- Comparative real-world survival outcomes of metastatic papillary and clear cell renal cell carcinoma treated with immunotherapy, targeted therapy, and combination therapy. (2023) (1)
- MK-6482, a hypoxia-inducible factor 2α inhibitor (HIF-2α), versus everolimus in heavily pretreated, immune checkpoint–inhibitor-resistant, advanced clear cell renal cell carcinoma (ccRCC): Phase III study. (2021) (1)
- The myeloid receptor TREM2 exacerbates DSS-induced colitis and promotes colitis-associated cancer (TUM4P.916) (2014) (1)
- The association between HSD3B1 genotype and steroid metabolism in normal and prostate cancer (PCa) tissue. (2018) (1)
- 200O Pembrolizumab plus axitinib (pembro + axi) vs sunitinib in metastatic renal cell carcinoma (mRCC) outcomes of the KEYNOTE-426 study in patients from eastern Asia (2020) (1)
- The Association between a Decrease in On-Treatment Neutrophil-to-Eosinophil Ratio (NER) at Week 6 after Ipilimumab Plus Nivolumab Initiation and Improved Clinical Outcomes in Metastatic Renal Cell Carcinoma (2022) (1)
- The impact of active smoking on survival outcome in metastatic renal cell carcinoma patients treated with targeted therapy. (2016) (1)
- PD2-3 Towards Optimal Management of Metastatic Renal Cell Carcinoma : an Update on the Role of Sunitinib as First-line Treatment (2008) (1)
- Patients with Hormone-Refractory Prostate Cancer A Pilot Trial of CTLA-4 Blockade with Human Anti-CTLA-4 in Updated (2007) (1)
- Organ Preservation for Recurrent Urethral Adenocarcinoma With Concurrent Chemotherapy and Radiation. (2017) (1)
- Long-term response to sunitinib treatment in metastatic renal cell carcinoma (mRCC). (2016) (1)
- MP44-01 A PROGNOSTIC MODEL FOR OVERALL SURVIVAL IN PATIENTS WITH METASTATIC CLEAR CELL RENAL CARCINOMA: RESULTS FROM CALGB 90206 (ALLIANCE) (2015) (1)
- Erratum to "B.I. Rini, E.J. Small, The potential for prostate cancer immunotherapy" (Crit. Rev. Oncol./Hematol. 46 (2003) S117-S127) (2012) (1)
- Maximizing the value of phase III trials in immuno-oncology: A checklist from the Society for Immunotherapy of Cancer (SITC) (2022) (1)
- Sunitinib in patients with metastatic renal cell carcinoma: Clinical outcome according to IMDC risk group. (2017) (1)
- Recent advances in molecularly targeted therapy in advanced renal cell carcinoma (2009) (1)
- The DART Study: A phase 2 randomized double-blind study of dalantercept plus axitinib versus placebo plus axitinib in advanced clear cell renal cell carcinoma (RCC). (2015) (1)
- Comprehensive molecular and genomic characterization of pancreatic tropism in metastatic renal cell carcinoma (2019) (1)
- Phase 3 study of first-line treatment with pembrolizumab + belzutifan + lenvatinib or pembrolizumab/quavonlimab + lenvatinib versus pembrolizumab + lenvatinib for advanced renal cell carcinoma (RCC). (2022) (1)
- B7H1 expression and association with clinical response to sunitinib therapy in patients with metastatic renal cell carcinoma (mRCC). (2013) (1)
- Discrepancy between reported progressive disease per radiology report and treating oncologist tumor measurements in patients with metastatic renal cell carcinoma (mRCC) receiving sunitinib. (2012) (1)
- Tivozanib in Patients with Advanced Renal Cell Carcinoma Previously Treated with Axitinib: Subgroup Analysis from TIVO-3 (2022) (1)
- Sunitinib ReversesType-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients (2008) (1)
- Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma (2018) (1)
- 843PLONG-TERM SAFETY WITH AXITINIB IN ADVANCED RENAL CELL CARCINOMA. (2014) (1)
- 717TiP Randomized, open-label, 3-arm phase III study comparing MK-1308A + lenvatinib and pembrolizumab (pembro) + belzutifan + lenvatinib versus pembro + lenvatinib as first-line (1L) treatment for advanced clear cell renal cell carcinoma (ccRCC) (2021) (1)
- Response to post-axitinib treatment in patients with metastatic renal cell carcinoma (2016) (1)
- Evaluation of patient (Pt), treatment, and prognostic factors in urinary tract adenocarcinoma. (2017) (1)
- Abstract PS7-01: Characteristics and outcomes of SARS-CoV-2 infection in patients with invasive breast cancer (BC) from the COVID-19 and cancer consortium (CCC19) cohort study (2021) (1)
- Abstract 2539: CTLA-4 blockade for hormone refractory prostate cancer: Dose-dependent induction of CD8+ T cell activation and clinical responses (2008) (1)
- Effect of pazopanib on myeloid-derived suppressor cells and T-cell function in patients with metastatic renal cell carcinoma. (2013) (1)
- Detection of circulating tumor cells in advanced renal cell carcinoma patients using microfilter-based capture (2012) (1)
- TIVO-3: Subgroup analysis of progression-free survival of tivozanib compared to sorafenib in subjects with refractory advanced renal cell carcinoma (RCC). (2019) (1)
- Abstract 3520: PBRM1 inactivation in renal cell cancer alters master transcription factor hub composition to repress instead of activate epithelial-differentiation (2017) (1)
- Association of PD-1 and PD-L1 protein expression in matched primary and metastatic renal cell carcinoma tumors. (2015) (1)
- Abstract 5365: Prolonged survival of patients with advanced renal cancer responding to multi-peptide vaccine IMA901 after single-dose cyclophosphamide (2012) (1)
- A phase I study of BMS-936558 plus sunitinib or pazopanib in patients with metastatic renal cell carcinoma. (2012) (1)
- Outcomes and patterns of disease progression in metastatic renal cell carcinoma patients treated with nivolumab. (2018) (1)
- Abstract 4378: Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma (2012) (1)
- Neoadjuvant durvalumab +/- tremelimumab affects the expression of immune checkpoint (IC) molecules on myeloid derived suppressor cells (MDSC) in patients (pts) with locally advanced renal cell carcinoma (RCC). (2019) (1)
- Impact of tumor size on survival outcome in metastatic renal cell carcinoma patients (mRCC) treated with targeted therapy. (2018) (1)
- Issue information (2013) (0)
- Modulation of Immune Effector and Regulator Cells by Sunitinib: Potential for Combination Therapy in Renal Cell Carcinoma Patients (2012) (0)
- Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma (2015) (0)
- Abstract 1184: The effect of dual VEGF/VEGFR inhibition on angiogenic signaling pathways. (2013) (0)
- Toward individualized treatment in urologic oncology. (2015) (0)
- Brain metastases in patients treated with targeted therapy for metastatic renal cell carcinoma (mRCC). (2011) (0)
- Association between primary tumor protein expression and response to sunitinib in patients with metastatic renal cell carcinoma. (2015) (0)
- Clinical Study Phase 1 study of mTORC 1 / 2 inhibitor sapanisertib ( TAK-228 ) in advanced solid tumours , with an expansion phase in renal , endometrial or bladder cancer (0)
- Resistance through Understanding the Molecular Basis of Response and New Strategies in Kidney Cancer : Therapeutic Advances (2010) (0)
- HIF-pathway genes prognostic for progression-free and overall survival in metastatic clear cell renal cell carcinoma (mccRCC). (2022) (0)
- The Rapidly Evolving Landscape of Immunotherapy in RCC (2018) (0)
- Circulating cell-free DNA (cfDNA) levels and fragmentation pattern can distinguish nonmuscle invasive (NMI) from muscle-invasive (MI) and metastatic (met) bladder cancer (BC). (2019) (0)
- A phase II trial of ketoconazole plus granulocyte/macrophage-colony stimulating factor (GM-CSF) in androgen independent prostate cancer (AIPC) patients (pts) (2005) (0)
- Serial changes in PD1/PDL1 expression in metastatic urothelial carcinoma (mUC) patients (pts) treated with immune checkpoint blockade (CPB). (2018) (0)
- Impact of neoadjuvant chemotherapy on pathologic outcomes in patients with upper tract urothelial carcinoma undergoing extirpative surgery. (2018) (0)
- Practice challenges afecting optimal care as identifed by US medical oncologists who treat renal cell carcinomas (2014) (0)
- Nonsystemic Approaches to the Management of Metastatic Renal Cell Carcinoma (2011) (0)
- 731 Concurrent immunotherapy and dipeptidyl peptidase-4 inhibition among patients with solid tumors (2021) (0)
- Erratum: "Axitinib for renal cell carcinoma" (Expert Opinion on Investigational Drugs (2008) 17 (5) (741-748)) (2008) (0)
- Phase III AXIS trial for second-line metastatic renal cell carcinoma (mRCC): Effect of prior first-line treatment duration and axitinib dose titration on axitinib efficacy. (2012) (0)
- Deferred cytoreductive nephrectomy among patients with newly diagnosed metastatic renal cell carcinoma treated initially with sunitinib. (2019) (0)
- Cancer Management Chapter 16: Urothelial and kidney cancers (2010) (0)
- Clinical outcomes of patients with metastatic renal cell carcinoma receiving subsequent therapy after progression on front-line immune-VEGF TKI combination therapy (2019) (0)
- 756 Active smoking is an adverse prognostic factor for survival outcome in metastatic renal cell carcinoma patients treated with targeted therapies (2016) (0)
- Clinical impact of an online tool to guide choice of therapy (Tx) for patients (Pts) with advanced renal cell carcinoma (RCC). (2013) (0)
- Prognostic markers assessment in invasive upper tract urothelial carcinoma (UTUC). (2016) (0)
- The impact of facility case volume on overall survival in patients with metastatic renal cell carcinoma in the targeted therapy era. (2018) (0)
- Issue information (2013) (0)
- Kidney Cancer Long-term Safety of Sunitinib in Metastatic Renal Cell Carcinoma (2015) (0)
- Association of the neutrophil to eosinophil ratio with response to immunotherapy-based combinations in metastatic renal cell carcinoma. (2021) (0)
- The von Hippel Lindau (VHL) gene status is not always identical in paired primary (P) and metastatic (M) lesion in patients with clear cell renal cell carcinoma (CCRCC) (2008) (0)
- PBRM1 Loss in Kidney Cancer Unbalances the Kidney Lineage Master Transcription Factor Hub to Repress Terminal Epithelial Fates (2019) (0)
- Evaluation of blood and tissue myeloid derived suppressor cells (MDSC), clinicopathologic factors, and pathologic response in urothelial carcinoma (UC). (2016) (0)
- Real-world experience with atezolizumab (atezo) in advanced urothelial cancer (UC). (2017) (0)
- MP64-13 NON-METASTATIC RENAL CANCERS OF MODERATE TO HIGH COMPLEXITY ARE AMENABLE TO PARTIAL NEPHRECTOMY AFTER NEOADJUVANT SUNITINIB (2014) (0)
- Phase II randomized study of dalantercept in combination with axitinib compared to axitinib alone as second-line treatment in patients with metastatic renal cell carcinoma. (2013) (0)
- V1022 ROBOTIC PARTIAL NEPHRECTOMY FOLLOWING NEOADJUVANT TYROSINE KINASE INHIBITOR TREATMENT (2011) (0)
- Association of cell-free DNA (cfDNA) levels with myeloid-derived suppressor cells (MDSC) levels in blood of patients (pts) with muscle invasive (MI) and metastatic (met) bladder cancer (BC). (2019) (0)
- Abstract 2505: Comprehensive molecular and genomic characterization of pancreatic tropism in metastatic renal cell carcinoma (2019) (0)
- Early Salvage Pelvic Radiation Therapy for Lymph Node–Positive Prostate Cancer Following Prostatectomy (2014) (0)
- Correlation of myeloid derived suppressor cell (MDSC) populations with clinicopathologic features in urothelial carcinoma (UC). (2016) (0)
- Predictors of progressive disease (PD) and subsequent outcomes in metastatic renal cell carcinoma (mRCC) patients (pts) treated with nivolumab (nivo). (2018) (0)
- Single-Cell VIPER Identifies Recurrence-Associated Renal Tumor Macrophages (2021) (0)
- Abstract SY27-03: Biomarker-guided development of novel multi-peptide cancer vaccines - from discovery to phase lll trials. (2013) (0)
- Target identification by phosphoproteomics: RIN1 modulation of sorafenib-induced cytotoxicity in renal cell carcinoma. (2009) (0)
- Impact of lymph node mets in mRCC. Eur Urol 2015 (2015) (0)
- V07-05 ROBOTIC-ASSISTED PARTIAL NEPHRECTOMY WITH INTRACORPOREAL HYPOTHERMIA AFTER PAZOPANIB TREATMENT IN A SOLITARY KIDNEY WITH SEGMENTAL VEIN THROMBOSIS (2018) (0)
- Phase I I T rial o f W eekly I ntravenous G emcitabine W ith Continuous I nfusion F luorouracil i n P atients W ith Metastatic R enal C ell C ancer (2000) (0)
- T cell infiltration in matched renal biopsy (bx) and nephrectomy (nx) samples in renal cell carcinoma (RCC). (2017) (0)
- The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma (2018) (0)
- Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma (2021) (0)
- Abstract 1117: Macrophage migration inhibitory factor (MIF) plays a critical role in clear cell renal carcinoma (2011) (0)
- Avelumab flat dose regimen: Justification for use in advanced renal cell carcinoma (aRCC). (2020) (0)
- Role of renal cell carcinoma in the induction of neutrophil dedifferentiation into myeloid-derived suppressor-like cells and the expression of immunosuppressive markers (2018) (0)
- Moderately hypofractionated radiotherapy for localized prostate cancer: Long-term outcomes for 854 consecutive patients treated over 10 years (70 Gy in 2.5 Gy/fraction). (2019) (0)
- Immunotherapy in Genitourinary Malignancies (2021) (0)
- Correlation between patient-reported fatigue and hemoglobin (Hgb) levels in metastatic renal cell carcinoma (mRCC) patients (pts) receiving sunitinib (SU). (2014) (0)
- Evaluation of prognostic factors in upper tract urothelial carcinoma (UTUC). (2016) (0)
- Consideration of the number of prostate biopsy samples found to be positive for cancer may add clinically useful information to T stage, Gleason score, and prostate-specific antigen level in predicting outcome after radical prostatectomy. Higher radi- (2001) (0)
- 906 Immunogenomic evaluation of clear cell renal carcinoma uncovers HK3 as a myeloid specific metabolic enzyme (2021) (0)
- Genomic testing enhances treatment choices and clinical trial accrual in metastatic colorectal cancer (CRC): Results of a prospective clinical study. (2015) (0)
- Genomic testing to enhance treatment choices and clinical trial accrual in metastatic colorectal cancer: Results of a prospective cohort study. (2015) (0)
- Integrating peripheral biomarker analyses from JAVELIN Renal 101: Avelumab + axitinib (A + Ax) versus sunitinib (S) in advanced renal cell carcinoma (aRCC). (2021) (0)
- Navigating and adapting care integrating immunotherapy, antiangiogenic therapy, and combinations in patients with advanced renal cell carcinoma (2023) (0)
- American Society of Clinical Oncology: Everolimus (RAD001) in renal cell carcinoma (2008) (0)
- Poster ViewingMolecular Profiling of Small Cell Bladder Cancer Reveals Gene Expression Determinants of an Aggressive Phenotype (2017) (0)
- Immune cell repertoire in patients with indolent metastatic renal cell carcinoma. (2013) (0)
- A phase II trial of interferon-alpha and celecoxib in metastatic renal carcinoma: clinical and anti-angiogenic effects. (2004) (0)
- Information Transparency in the Drug Approval Process. (2018) (0)
- Current and emerging first-line systemic therapies in clear cell renal cell carcinoma. (2018) (0)
- Phase II trial of sunitinib as maintenance therapy after stereotactic radiosurgery in patients with one to three newly diagnosed brain metastases. (2010) (0)
- Abstract B213: Pharmacokinetics (PK) and efficacy of axitinib in patients (pts) with sorafenib‐refractory metastatic renal cell carcinoma (mRCC) (2009) (0)
- Association between on-treatment eosinophil dynamics and outcomes in metastatic renal cell carcinoma patients treated with ipilimumab/nivolumab. (2022) (0)
- Re: Hypertension as a Biomarker of Efficacy in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib Response (2011) (0)
- LBA01-08 INTERIM ANALYSIS OF PADRES (PRIOR AXITINIB AS A DETERMINANT OF OUTCOME OF RENAL SURGERY NCT03438708) CLINICAL TRIAL (2022) (0)
- Sorafenib in Advanced Renal Cancer (2012) (0)
- The association between PSA pattern changes and progression in patients with metastatic hormone-sensitive prostate cancer (mHSPC) treated with abiraterone and prednisone (AA/P). (2020) (0)
- Genotype correlations with blood pressure and efficacy outcomes from the randomized phase III AXIS trial of second-line axitinib versus sorafenib in metastatic renal cell carcinoma. (2014) (0)
- Patient/treatment characteristics and prognostic factors in small-cell bladder cancer (SCBC). (2016) (0)
- Clinical and Management Implications Associated with Histologic Subtypes of Renal Cell Carcinomas (2015) (0)
- Correlation of myeloid-derived suppressor cells (MDSC) with pathologic complete response (pCR), recurrence free survival (RFS), and overall survival (OS) in patients with urothelial carcinoma (UC) undergoing cystectomy. (2019) (0)
- Therapeutic considerations in patients with metastatic renal cell carcinoma previously treated with antiangiogenic therapies. (2006) (0)
- Cisplatin-based neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) in patients (pts) with impaired renal function. (2018) (0)
- Challenges with genomic testing in pancreaticobiliary cancers: Results of a prospective cohort study. (2015) (0)
- The impact of switching systemic treatment after radiosurgery (SBRT) for oligo-progressive, metastatic renal cell carcinoma (mRCC). (2018) (0)
- Impact of PSMA-targeted PET/CT in the clinical management of men with advanced prostate cancer. (2022) (0)
- Comparative effectiveness of tumor response assessment methods: Standard-of-care versus computer-assisted response evaluation. (2017) (0)
- 633 Incorporating checkpoint inhibitors into cancer care: a study of the impact of digital education on clinical competence and practice patterns (2021) (0)
- Adult UrologyOncology: Adrenal/Renal/Upper Tract/BladderEditorial Comment (2008) (0)
- RAMPART: A model for a regulatory-ready academic-led phase III trial in the adjuvant renal cell carcinoma setting. (2021) (0)
- Erratum: Cessation of vascular endothelial growth factortargeted therapy in patients with metastatic renal cell carcinoma. (Cancer (2012) DOI: 10.1002/cncr.26666) (2012) (0)
- Durable complete responses and near complete responses to sunitinib in metastatic renal cell carcinoma (2007) (0)
- Racial disparities in the outcomes of transitional cell carcinoma of the bladder: A population-based analysis. (2020) (0)
- PD03-10 COMPREHENSIVE MOLECULAR AND GENOMIC CHARACTERIZATION OF PANCREATIC TROPISM IN METASTATIC RENAL CELL CARCINOMA (2019) (0)
- Therapeutics , Targets , and Chemical Biology Noncytotoxic Differentiation Treatment of Renal Cell Cancer (2011) (0)
- The effect of deep AR suppression with enzalutamide or apalutamide on endogenous glucocorticoids: Implications for adverse effects and development of combination therapies. (2020) (0)
- Editorial comment. (2010) (0)
- 349 Tolerability of tivozanib vs. sorafenib in elderly and/or immunotherapy-pretreated patients with metastatic renal cell cancer (mRCC) in TIVO-3 (2021) (0)
- VEGF: Biologic Aspects and Clinical Approaches (2009) (0)
- Analysis of an online tool to explore evolving practice patterns in renal cell carcinoma (RCC). (2018) (0)
- SUN-739 Next Generation AR Antagonists Increase Systemic Active Glucocorticoid Exposure by Altering Glucocorticoid Metabolism (2020) (0)
- Mammalian target of rapamycin inhibitors: the beginning of the end or the end of the beginning? (2014) (0)
- Characteristics of metastatic renal cell carcinoma (mRCC) patients treated with delayed targeted therapy: Results from the International mRCC Consortium (IMDC). (2015) (0)
- Descriptive comparison of hospital formulary decisions with published oncology valuation methods (2020) (0)
- Highlights in renal cell carcinoma from the 2012 American Society of Clinical Oncology Annual Meeting. (2012) (0)
- Patients with metastatic renal cell carcinoma who benefit from axitinib dose titration: analysis from a randomised, double-blind phase II study (2019) (0)
- Initial report on hospitalized cancer patients with COVID-19 from the National Cancer Institute (NCI) COVID-19 in Cancer Patients Study (NCCAPS). (2021) (0)
- Predictive biomarkers of overall survival in patients with renal cell carcinoma treated with interferon alpha +/- bevacizumab: Results from CALGB 90206 (Alliance). (2021) (0)
- PD39-03 HYPOXIA-INDUCIBLE FACTOR (HIF) PATHWAY GENES PREDICT OVERALL SURVIVAL FOR METASTATIC CLEAR CELL RENAL CELL CARCINOMA (2020) (0)
- Gender impact on renal cell carcinoma survival: A population-based analysis. (2020) (0)
- Flow cytometric detection of MDSC populations in unfractionated blood. (2017) (0)
- MP78-11 DO SARCOMATOID AND RHABDOID DIFFERENTIATION HAVE SIMILAR PROGNOSTIC EFFECTS FOR PATIENTS WITH GRADE 4 RENAL CELL CARCINOMA? (2016) (0)
- 294 EFFECT OF PAZOPANIB ON MYELOID DERIVED SUPPRESSOR CELLS AND T CELL FUNCTION IN METASTATIC RENAL CELL CARCINOMA PATIENTS (2013) (0)
- Medical Management of Metastatic Renal Cell Carcinoma (2015) (0)
- Abstract A100: Seamless phase I/II clinical trials in oncology: retrospective analysis of the last 7 years (2018) (0)
- Association of tumor burden characteristics with outcomes in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib. (2009) (0)
- Conditional survival (CS) for patients with metastatic renal cell carcinoma (mRCC) treated with vascular endothelial growth factor (VEGF)-targeted therapy (TT): Results from the International mRCC Database Consortium. (2012) (0)
- Optimal treatment by invoking biologic clusters in renal cell carcinoma (OPTIC RCC). (2023) (0)
- Q-TWiST analysis of tivozanib (T) versus sorafenib (S) in patients with advanced renal cell carcinoma (RCC) in the TIVO-3 study. (2021) (0)
- The Wolchok/Motzer article reviewed (2000) (0)
- Metastatic non-clear cell renal cell carcinoma (nccRCC) treated with targeted therapy agents: Applying the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) prognostic model to predict outcomes. (2013) (0)
- The addition of imatinib mesylate to estramustine/docetaxel (E/D) for the treatment of hormone refractory prostate cancer (HRPC) patients: Results of a phase I trial (2004) (0)
- Relapse models for clear cell renal carcinoma - Authors' reply. (2015) (0)
- Department of Error (2012) (0)
- Treatment patterns for metastatic hormone-sensitive prostate cancer (mHSPC) progressing after up-front docetaxel in combination with androgen deprivation therapy (D-ADT). (2018) (0)
- Phase II trial of intermittent therapy in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with front-line ipilimumab and nivolumab (Ipi/Nivo). (2023) (0)
- Review State of the Science : An Update on Renal Cell Carcinoma (2012) (0)
- 1018: Immunotherapy (APC8015) for Androgen Dependent, Biochemically-Relapsed Prostate Cancer (2005) (0)
- Rheumatologic immune-related adverse events (irAE) in patients (pts) with genitourinary (GU) malignancies treated with immune checkpoint inhibitors (CPI). (2018) (0)
- response from a randomized phase II study in metastatic renal cell carcinoma (2015) (0)
- PD40-09 ASSOCIATION BETWEEN PRIOR NEPHRECTOMY AND EFFICACY OF IMMUNE CHECKPOINT INHIBITOR THERAPY IN METASTATIC RENAL CELL CARCINOMA - A SYSTEMATIC REVIEW AND META-ANALYSIS (2021) (0)
- response from a randomized phase II study in metastatic renal cell carcinoma (2015) (0)
- 1658 METASTASECTOMY FOLLOWING TARGETED THERAPY IN PATIENTS WITH RENAL CELL CARCINOMA (2010) (0)
- Axitinib plus immune checkpoint inhibitor: evidence- and expert-based consensus recommendation for treatment optimisation and management of related adverse events (2020) (0)
- Data to decisions: The impact of online education on immunotherapy in advanced renal cell carcinoma. (2020) (0)
- Impact of preoperative neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) on overall survival or recurrence free survival in muscle-invasive bladder cancer at cystectomy. (2020) (0)
- FDA pooled analysis of time to treatment discontinuation (TTD) in frontline advanced renal cell carcinoma trials. (2020) (0)
- Post-axitinib systemic therapy in metastatic renal cell carcinoma (mRCC). (2012) (0)
- Topical overview New approaches in advanced renal cell carcinoma (2005) (0)
- Phase 1b/2 umbrella study of investigational immune and targeted combination therapies for patients with advanced clear cell renal cell carcinoma (ccRCC). (2022) (0)
- Clinically Useful Biomarkers in Metastatic Renal Cell Carcinoma (2021) (0)
- Safety and Efficacy of Nivolumab in PatientsWithMetastatic Renal Cell Carcinoma Treated Beyond Progression A Subgroup Analysis of a Randomized Clinical Trial (2016) (0)
- 6 First and further lines of therapy in clear cell renal cell carcinoma (2011) (0)
- Limiting allogeneic bone marrow transplantation based on psychosocial criteria: A comparison of professional attitudes (2005) (0)
- Role of quantitative gene expression using RT-PCR in the prediction of recurrence risk in resected T1 clear cell renal cell carcinoma (ccRCC). (2011) (0)
- Retrospective analysis of risk factors for fatigue in clinical trial patients (pts) with metastatic renal cell carcinoma (mRCC). (2013) (0)
- 7 Characterizing the impact of lymph node metastases on survival outcome of metastatic renal cell carcinoma patients treated with targeted therapies (2015) (0)
- 359 Correlation of tumour-associated macrophage, but not tumour-infiltrating lymphocyte, levels with progression-free survival in patients with metastatic renal cell carcinoma treated with axitinib (2014) (0)
- Nonsurgical Management of Metastatic Renal Cell Carcinoma (2008) (0)
- A Multicenter Validation Study of Genetic Polymorphisms Associated With Toxicity and Efficacy of Sunitinib in Patients With Metastatic Renal Cell Carcinoma. (2015) (0)
- Phase II study of axitinib prior to partial nephrectomy to preserve renal function: An interim analysis of the PADRES clinical trial. (2023) (0)
- Blood myeloid derived suppressor cells (MDSC) in metastatic urothelial carcinoma (mUC) are correlated with neutrophil-to-lymphocyte ratio (NLR) and overall survival (OS). (2019) (0)
- Additional Tyrosine Kinase Inhibitors in Renal Cell Carcinoma (2009) (0)
- Early PSA decline as a predictor of progression in patients with metastatic castration-naïve prostate cancer (mCNPC) treated with abiraterone acetate and prednisone (AA/P). (2020) (0)
- The addition of imatinib mesylate to estramustine/docetaxel (E/D) for the treatment of hormone refractory prostate cancer (HRPC) patients: Results of a phase I trial. (2004) (0)
- Abstracts: ASCPT 2016 Annual Meeting & Quantitative Translational Approaches in Oncology Pre-Conference. (2016) (0)
- Prognostic value of CD56, ASCL1, and other biomarkers in small cell bladder cancer (SCBC). (2018) (0)
- 1006 ORAL Prognostic Factors for Progression-free Survival (PFS), Overall Survival (OS), and Long-term OS (LT-OS) With Sunitinib in 1,059 Patients, Treated on Clinical Trials, With Metastatic Renal Cell Carcinoma (mRCC) (2011) (0)
- Temsirolimus in VEGF-refractory metastatic renal cell (2011) (0)
- Immunotherapy for prostate cancer (2001) (0)
- Changing Landscape of Refractory Renal Cell Carcinoma. (2016) (0)
- HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism (2017) (0)
- Genitourinary oncology referral patterns to the cancer associated thrombosis clinic: The Cleveland Clinic experience. (2020) (0)
- A phase II and biomarker study (MET111644) of the dual Met/VEGFR-2 inhibitor foretinib in patients with sporadic and hereditary papillary renal cell carcinoma: Final efficacy, safety, and PD results. (2012) (0)
- SPEAK UP: Itʼs Easier to Target the Tumor than the Patient (2010) (0)
- Response to platinum-based therapy (PBT) and immune checkpoint inhibitors (ICI) in metastatic urothelial carcinoma (mUC) patients (pts) with genomic alterations (GA) in homologous recombination repair (HRR) genes. (2018) (0)
- Abstract CT243: A phase 1b/2 umbrella study of investigational immune and targeted combination therapies for patients with advanced renal cell carcinoma (RCC) who progressed on PD-1/L1 and VEGF inhibitors (2021) (0)
- Comprehensive molecular and genomic characterization of pancreatic tropism in metastatic renal cell carcinoma. (2019) (0)
- Correlation of genomic alterations with outcome in patients (pts) with urothelial carcinoma (UC). (2016) (0)
- Evaluation of response to enzalutamide (E) consecutively after disease progression on abiraterone/prednisone (AP) and potential predictors of response. (2016) (0)
- Response to post-axitinib treatment in patients with metastatic renal cell carcinoma (2016) (0)
- Circulating tumor cells in metastatic castration-resistant prostate cancer (2009) (0)
- Third-Generation TKIs (Axitinib, Tivozanib) in RCC: Enhanced Efficacy and Diminished Toxicity? (2015) (0)
- Associated with T Cell Dysfunction Cells from Renal Cell Carcinoma Patients Is Elevated Levels of Select Gangliosides in T (2013) (0)
- Cytoreductive radical nephrectomy (cRN) and level II-IV infereior vena cava (IVC) thrombectomy for metastatic renal cell carcinoma (mRCC). (2012) (0)
- Tyrosine Kinase Inhibitors: Sorafenib, Sunitinib, Axitinib, and Pazopanib (2017) (0)
- Achieving “Zero PSA” Following Post-Prostatectomy Radiation Therapy for Lymph Node Positive Prostate Cancer in the Ultrasensitive PSA Era (2018) (0)
- Immunological correlates of response to immune checkpoint inhibitors (ICI) in metastatic urothelial carcinoma (mUC) patients (pts). (2018) (0)
- Myeloid derived suppressor cells (MDSC) and inflammatory biomarkers in metastatic urothelial carcinoma (mUC). (2017) (0)
- Conditional survival (CS) for patients with metastatic renal cell carcinoma (mRCC) treated with vascular endothelial growth factor (VEGF)-targeted therapy (TT): Results from the International mRCC Database Consortium. (2012) (0)
- Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma. (2022) (0)
- Clinical outcome of gamma knife (GK) radiotherapy for central nervous system (CNS) metastases from renal cell carcinoma (RCC). (2011) (0)
- The association of D4, 3-keto-abi (D4A) and response to abiraterone in castration-resistant prostate cancer (CRPC). (2016) (0)
- Long-term duration of axitinib treatment in advanced renal cell carcinoma (2016) (0)
- 7140 POSTER A Randomized Phase 2 Study of Axitinib Dose Titration in Patients With Advanced Renal Cell Carcinoma (RCC): Preliminary Pharmacokinetic and Ambulatory Blood Pressure (BP) Monitoring Results (2011) (0)
- Perspectives on under-representation of minority patients (pts) in clinical trials. (2021) (0)
- Treatment response and survival outcome of patients with late relapse (LR) from renal cell carcinoma (RCC) in the era of targeted therapy. (2013) (0)
- The association between the treatment-induced hypertension (Htn) and response to neoadjuvant sunitinib in renal cell carcinoma (RCC). (2012) (0)
- Implications of the United States Preventive Services Task Force (USPSTF) recommendations on prostate cancer (PCa) stage migration. (2019) (0)
- Abstract 5599: Soluble PD-L1 as a surrogate biomarker of metastatic progression and resistance to antiangiogenic therapy (2017) (0)
- Erratum to ‘Efficacy and correlative analyses of avelumab plus axitinib versus sunitinib in sarcomatoid renal cell carcinoma: post hoc analysis of a randomized clinical trial’ (2021) (0)
- Change in International mRCC Database Consortium (IMDC) prognostic category and implications for efficacy of second-line targeted therapy. (2016) (0)
- Multicenter retrospective analysis of patients with metastatic renal cell carcinoma (mRCC) and bone metastases treated with ipilimumab and nivolumab. (2020) (0)
- Temporal Characteristics of Adverse Events of Tivozanib and Sorafenib in Previously Treated Kidney Cancer. (2022) (0)
- Cytoreductive radical nephrectomy (cRN) and level II-IV infereior vena cava (IVC) thrombectomy for metastatic renal cell carcinoma (mRCC). (2012) (0)
- Reply to S. Tan et al. (2022) (0)
- 1107 Outcomes of patients with non clear cell renal cell carcinoma treated with targeted therapy and prognostication using the International mRCC Database Consortium Criteria (2013) (0)
- Myeloid derived suppressor cells (MDSC) correlate with inflammatory biomarkers in metastatic urothelial carcinoma (mUC) (2017) (0)
- The impact of marital status on the survival of transitional cell carcinoma of the bladder. (2020) (0)
- Editorial comment. (2009) (0)
- Is Guillain Barré Syndrome Likely in This Patient (2008) (0)
- OP-JNCI200067 1..10 (2020) (0)
- Atezolizumab (atezo) and subsequent therapies in patients (Pts) with metastatic urothelial carcinoma (mUC) outside clinical trials. (2018) (0)
- Notice of retraction: "Therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: biology, clinical results and future development" (BJUI, Volume 96, Issue 3, pages 286 – 290). (2012) (0)
- Phase I expansion study of sunitinib and bevacizumab in patients with advanced solid malignancies. (2013) (0)
- Clinical outcomes according to ethnicity in patients with metastatic renal cell carcinoma (mRCC) treated with VEGF-targeted therapy (TT). (2017) (0)
- Immune cell repertoire in patients with metastatic renal cell carcinoma: Data from prospective clinical trial. (2015) (0)
- TIVO-3: Age-related tolerability outcomes of tivozanib versus sorafenib in metastatic relapsed or refractory renal cell carcinoma, a subgroup analysis of the TIVO-3 clinical trial. (2021) (0)
- ANZUP Scientific Program and Pre‐Conference Meetings (2015) (0)
- Abstract 2572:HSD3B1genotype and abiraterone metabolism in patients with prostate cancer (2018) (0)
- C-reactive protein (CRP) as a predictive marker for outcomes with avelumab + axitinib (A + Ax) in patients with poor-risk advanced renal cell carcinoma (aRCC): Exploratory analysis from JAVELIN Renal 101. (2023) (0)
- Checkpoint inhibitors in metastatic renal cell carcinoma patients including elderly subgroups: Results from the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC). (2017) (0)
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What Schools Are Affiliated With Brian I. Rini?
Brian I. Rini is affiliated with the following schools:
- University of Texas Southwestern Medical Center
- Harvard University
- University of Calgary
- MD Anderson Cancer Center
- Wayne State University
- University of Chicago
- University of Toronto
- University of Iowa
- University of California, San Francisco
- Baylor University
- Aarhus University
- Medical University of South Carolina
- Vanderbilt University
- Sumy State University
- Stanford University
- Case Western Reserve University