Bríd Ryan
Irish biomedical scientist
Bríd Ryan's AcademicInfluence.com Rankings
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Law Biology
Bríd Ryan's Degrees
- Bachelors Biomedical Science National University of Ireland
- PhD Biomedical Science Trinity College Dublin
Why Is Bríd Ryan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bríd M. Ryan is an Irish biomedical scientist and cancer researcher. She was an investigator at the National Cancer Institute from 2013 to 2021. Early life and education Ryan grew up on a farm and dairy in Ireland. She has five sisters. Ryan always enjoyed science and decided she wanted to be a cancer researcher as a teenager. She completed her undergraduate training in biochemistry at University College Cork in 2001. Ryan received her Ph.D. in Cancer Biology from St. Vincent’s University Hospital and UCD School of Medicine and in 2005 was accepted into the National Cancer Institute Cancer Prevention Fellowship Program. In 2007, she completed a Masters of Public Health at School of Public Health and Population Sciences, University College Dublin. Ryan worked under the mentorship of Curtis C. Harris during her postdoctoral training at the NCI. As a postdoc at NCI, she was involved in research that bridged both basic science and translational molecular epidemiology. Initially, Ryan studied populations of European descent, but it became clear that, within the United States, significant disparities in incidence and survival existed across populations.
Bríd Ryan's Published Works
Published Works
- Genetic variation in microRNA networks: the implications for cancer research (2010) (1226)
- Survivin: a new target for anti-cancer therapy. (2009) (377)
- Survivin: a promising tumor biomarker. (2007) (269)
- Interaction between the microbiome and TP53 in human lung cancer (2018) (195)
- Assessment of Variability in the SOMAscan Assay (2017) (188)
- Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1. (2006) (155)
- Microenvironmental modulation of asymmetric cell division in human lung cancer cells (2010) (125)
- ADAM-17 Expression in Breast Cancer Correlates with Variables of Tumor Progression (2007) (115)
- Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer (2004) (93)
- ADAM-17 predicts adverse outcome in patients with breast cancer. (2008) (92)
- rs4919510 in hsa-mir-608 Is Associated with Outcome but Not Risk of Colorectal Cancer (2012) (69)
- Comparative Transcriptome Profiling Reveals Coding and Noncoding RNA Differences in NSCLC from African Americans and European Americans (2017) (68)
- 3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans. (2012) (65)
- Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer. (2015) (59)
- Cytokine Storms in Cancer and COVID-19 (2020) (52)
- Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer (2014) (51)
- Lung cancer health disparities. (2018) (48)
- A Combined Prognostic Serum Interleukin-8 and Interleukin-6 Classifier for Stage 1 Lung Cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (2014) (43)
- Body mass index (BMI), BMI change, and overall survival in small cell and non-small cell lung cancer patients: a pooled analysis of the International Lung Cancer Consortium. (2019) (39)
- Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population. (2016) (38)
- Histologic Lung Cancer Incidence Rates and Trends Vary by Race/Ethnicity and Residential County (2018) (38)
- The hallmarks of premalignant conditions: a molecular basis for cancer prevention. (2016) (32)
- Differential Serum Cytokine Levels and Risk of Lung Cancer Between African and European Americans (2015) (31)
- microRNAs in Cancer Susceptibility (2017) (30)
- KRAS-LCS6 Genotype as a Prognostic Marker in Early-Stage CRC–Letter (2012) (29)
- Relationship between anti-depressant use and lung cancer survival. (2017) (28)
- Identification of serum inflammatory markers as classifiers of lung cancer mortality for stage I adenocarcinoma (2017) (26)
- Genetic variation in microRNA networks: the implications for cancer research (2010) (26)
- IFNL4-ΔG is associated with prostate cancer among men at increased risk of sexually transmitted infections (2018) (25)
- An analysis of genetic factors related to risk of inflammatory bowel disease and colon cancer. (2014) (25)
- Mammaglobin a in breast cancer: Existence of multiple molecular forms (2005) (24)
- Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans (2020) (24)
- MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer (2012) (23)
- A DRD1 Polymorphism Predisposes to Lung Cancer among Those Exposed to Secondhand Smoke during Childhood (2014) (23)
- Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate (2016) (22)
- Differential eligibility of African American and European American lung cancer cases using LDCT screening guidelines (2016) (22)
- Relationship between Circulating Inflammation Proteins and Lung Cancer Diagnosis in the National Lung Screening Trial (2018) (22)
- Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans (2019) (22)
- A Two‐Gene Prognostic Classifier for Early‐Stage Lung Squamous Cell Carcinoma in Multiple Large‐Scale and Geographically Diverse Cohorts (2017) (20)
- Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. (2019) (19)
- The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients. (2020) (16)
- Circulating Inflammation Proteins Associated With Lung Cancer in African Americans. (2019) (15)
- Whole Exome Profiling of NSCLC Among African Americans. (2020) (15)
- Heme‐related gene expression signatures of meat intakes in lung cancer tissues (2014) (14)
- A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing (2021) (14)
- Lipophilin B: A gene preferentially expressed in breast tissue and upregulated in breast cancer (2006) (14)
- Inverse association of vitamin D3 levels with lung cancer mediated by genetic variation (2018) (13)
- Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines (2013) (13)
- JAK/STAT of all trades: Linking inflammation with cancer development, tumor progression, and therapy resistance. (2021) (13)
- Innate immunity gene polymorphisms and the risk of colorectal neoplasia. (2013) (10)
- Relationship between West African ancestry with lung cancer risk and survival in African Americans (2019) (10)
- KRT81 miR-SNP rs3660 is associated with risk and survival of NSCLC. (2016) (9)
- Understanding the Role of Dopamine in Cancer: Past, Present, and Future. (2022) (8)
- MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer (2016) (8)
- Racial and Ethnic Differences in the Relationship between Aspirin Use and Non–Small Cell Lung Cancer Risk and Survival (2018) (7)
- Smoking cessation (SC) and lung cancer (LC) outcomes: A survival benefit for recent-quitters? A pooled analysis of 34,649 International Lung Cancer Consortium (ILCCO) patients. (2020) (6)
- Author Correction: Interaction between the microbiome and TP53 in human lung cancer (2020) (6)
- Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma (2022) (5)
- Elevated Serum Megakaryocyte Potentiating Factor as a Predictor of Poor Survival in Patients with Mesothelioma and Primary Lung Cancer. (2018) (4)
- Microbiome-TP53 Gene Interaction in Human Lung Cancer (2018) (4)
- Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing (2018) (4)
- Automated next-generation profiling of genomic alterations in human cancers (2022) (3)
- Evidence that the Lung Adenocarcinoma EML4-ALK Fusion Gene Is not Caused by Exposure to Secondhand Tobacco Smoke During Childhood (2014) (3)
- A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients (2021) (3)
- Interaction between the microbiome and TP53 in human lung cancer (2018) (3)
- Creatine riboside is a cancer cell–derived metabolite associated with arginine auxotrophy (2022) (3)
- Abstract PR07: Role of the microbiota in inflammation and lung cancer (2018) (3)
- A systematic genome-wide mapping of the oncogenic risks associated with CRISPR-Cas9 editing (2018) (3)
- Prenatal smoke exposure, DNA methylation and a link between DRD1 and lung cancer. (2019) (3)
- Abstract 4581: Interaction between DRD1 and childhood exposure to environmental tobacco smoke modulates lung cancer risk in smokers and never smokers. (2013) (2)
- LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner (2022) (2)
- Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias (2021) (2)
- Clinical outcomes and immune phenotypes associated with STK11 co-occurring mutations in non-small cell lung cancer (2021) (2)
- Survivin protein expression predicts poor outcome in patients with primary breast cancer (2005) (2)
- Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing (2022) (1)
- Using a Recently Approved Tumor Mutational Burden Biomarker to Stratify Patients for Immunotherapy May Introduce a Sex Bias. (2021) (1)
- A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels (2022) (1)
- Stressing the need to overcome EGFR tyrosine kinase inhibitor resistance. (2018) (1)
- 8-24-2018 Interaction between the microbiome and TP 53 in human lung cancer (2018) (1)
- Abstract B60: Inflammatory-based diagnostic markers of lung cancer in African Americans (2017) (1)
- Identifying therapeutic vulnerabilities in lung cancer: application of a chemistry-first approach. (2018) (1)
- Abstract 4320: Circulating vitamin D2 and D3 levels and single nucleotide polymorphism associations with lung cancer status: A case-control study (2016) (1)
- Abstract LB-182: Improved survival among lung cancer patients taking antidepressants (2015) (1)
- Prevention and Epidemiology 3 0-UTR and Functional Secretor Haplotypes in Mannose-Binding Lectin 2 Are Associated with Increased Colon Cancer Risk in African Americans (2012) (1)
- Gene expression classifier for prognosis of early-stage squamous cell carcinoma of the lung (2016) (1)
- A functional SNP in MRPL43 modulates lung cancer susceptibility and survival through alternative splicing of its isoforms (2016) (1)
- Author Correction: Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans (2020) (1)
- Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines (2013) (1)
- Author Correction: Interaction between the microbiome and TP53 in human lung cancer (2020) (0)
- Relationship between the TP53 SNP rs1800371 and Lung Cancer in African Americans (2019) (0)
- Racial Disparities in Cigarette Smoking Behaviors and Differences Stratified by Metropolitan Area of Residence (2022) (0)
- Abstract 4658: Inflammatory based diagnostic markers of lung cancer in African Americans (2017) (0)
- Global profiling of alternative splicing in non-small cell lung cancer reveals novel histological and population differences (2022) (0)
- Abstract LB-295: Analysis of miR-21 isomiRs in lung cancer (2015) (0)
- Abstract 1265: The effects of ancestry and histology on the lung tumor methylome (2020) (0)
- Abstract 1171: From genotypes to phenotypes: genetic variation in microRNA-related genes and lung cancer risk (2011) (0)
- Higher prevalence of homologous recombination-deficiency in lung squamous carcinoma from African Americans (2019) (0)
- Abstract B60: Hsa-miR-27a drives an association of MBL2 3′UTR haplotype with colon cancer risk in African Americans (2011) (0)
- In Response: Using Propensity Score Matching to Balance the Baseline Characteristics. (2021) (0)
- Abstract 3406: The identification of serum cytokine inflammatory markers as classifiers of lung cancer mortality for stage I lung adenocarcinoma: a retrospective cohort study (2016) (0)
- NNAL, a major metabolite of tobacco-specific carcinogen NNK, promotes lung cancer progression through deactivating LKB1 in an isomer-dependent manner (2021) (0)
- Abstract A4: Integrative genomic analysis of lung cancer: Focus on health disparities (2011) (0)
- Abstract IA02: Genetic, environmental, and biological contributions to racial disparities in lung cancer incidence (2016) (0)
- Abstract B61: Insights into lung cancer survival in African Americans from a study of germline variation in the microRNA network (2011) (0)
- IFNL4-ΔG is associated with prostate cancer among men at increased risk of sexually transmitted infections (2018) (0)
- Sex biases in cancer and autoimmune disease incidence are correlated across human tissues (2021) (0)
- Abstract 2156: Childhood exposure to secondhand smoke, nicotine dependence, and DRD1 are associated with lung cancer risk (2014) (0)
- Does ethnicity affect the relationship between body mass index (BMI) and overall survival (OS) in non-small cell lung cancer (NSCLC)? A pooled analysis of 17,326 International Lung Cancer Consortium (ILCCO) patients (pts). (2019) (0)
- Respiratory and cardiometabolic comorbidities and Stage I-III non-small cell lung cancer (NSCLC) survival: A pooled analysis from the International Lung Cancer Consortium (ILCCO). (2022) (0)
- Abstract 382: MTL-STING restores endogenous STING expression for improving efficacy of cancer therapeutics (2022) (0)
- Abstract 4238: Human non-small cell lung cancer cells asymmetrically divide their template DNA strands and cell fate proteins (2010) (0)
- Chapter 4:The Role of Catecholamines in Stem Cell Mobilisation (2016) (0)
- Abstract 29: The recently approved high-TMB criteria may introduce a sex bias in response to PD1 inhibitors (2021) (0)
- Assessment of Variability in the SOMAscan Assay (2017) (0)
- Abstract #176: Identification of cancer stem cells in small cell lung cancer (2009) (0)
- Abstract A111: Racial differences in the relationship between dimensions of smoking exposure and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium Study (2020) (0)
- Small RNAs/Cancer (2016) (0)
- Abstract 2860: NOSTRIN-induced inhibition of pancreatic cancer progression involves CCBE1 in an eNOS-independent manner (2021) (0)
- Association of Neighborhood Deprivation With Prostate Cancer and Immune Markers in African American and European American Men (2023) (0)
- Abstract 4925: Microbiome-TP53 gene interaction in human lung cancer (2017) (0)
- 280 POSTER ADAM-17: A role in breast cancer progression (2006) (0)
- Abstract B30: Lung cancer in African Americans is characterized by histone modifying enzyme gene signatures (2016) (0)
- Abstract A35: A pluripotency reporter defines lung cancer cells with tumor-initiating properties. (2014) (0)
- Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data. (2022) (0)
- Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues (2022) (0)
- P14. ADAM-17: A mediator of breast cancer progression? (2006) (0)
- Abstract PO-234: Relationship between increased concentrations of circulating chemokines and population differences in tumor biology (2020) (0)
- Abstract IA29: Racial differences in the lung cancer transcriptome: Insights from coding, noncoding, and alternative polyadenylated genes (2020) (0)
- Abstract 4423: Deep sequencing of lung cancer samples using different library preparation methods produces discordant short non-coding RNA profiles (2017) (0)
- Abstract A34: Regulation of EGFR signaling by DRD1 in lung cancer (2018) (0)
- A reply to "Lung cancer outcomes: Are BMI and race clinically relevant?" (2021) (0)
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