Britta Engelhardt
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German biologist and immunologist
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(Suggest an Edit or Addition)Britta Engelhardt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A mechanosensory complex that mediates the endothelial cell response to fluid shear stress (2005) (1528)
- C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE (2009) (1099)
- The anatomical and cellular basis of immune surveillance in the central nervous system (2012) (770)
- The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. (2005) (631)
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (2019) (627)
- The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction (2009) (620)
- The movers and shapers in immune privilege of the CNS (2017) (527)
- Capture, crawl, cross: the T cell code to breach the blood-brain barriers. (2012) (524)
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (2017) (520)
- Development of the blood-brain barrier (2003) (491)
- Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles (2003) (459)
- Endothelial Cell Laminin Isoforms, Laminins 8 and 10, Play Decisive Roles in T Cell Recruitment across the Blood–Brain Barrier in Experimental Autoimmune Encephalomyelitis (2001) (457)
- Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme (2003) (426)
- Strategies to advance translational research into brain barriers (2008) (414)
- Mini‐review: Transendothelial migration of leukocytes: through the front door or around the side of the house? (2004) (364)
- Brain barriers: Crosstalk between complex tight junctions and adherens junctions (2015) (358)
- Molecular mechanisms involved in T cell migration across the blood–brain barrier (2006) (340)
- Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels. (2001) (337)
- Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. (2002) (324)
- Perivascular Spaces and the Two Steps to Neuroinflammation (2008) (302)
- Alpha4 integrins as therapeutic targets in autoimmune disease. (2003) (270)
- Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse. (2000) (260)
- Vascular, glial, and lymphatic immune gateways of the central nervous system (2016) (251)
- Improving Outcome after Stroke: Overcoming the Translational Roadblock (2008) (248)
- Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier (2013) (235)
- Diapedesis of mononuclear cells across cerebral venules during experimental autoimmune encephalomyelitis leaves tight junctions intact (2005) (231)
- A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells (2014) (231)
- Multistep Nature of Microvascular Recruitment of Ex Vivo–expanded Embryonic Endothelial Progenitor Cells during Tumor Angiogenesis (2003) (231)
- Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. (1994) (229)
- ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro. (1996) (227)
- Review: Leucocyte–endothelial cell crosstalk at the blood–brain barrier: A prerequisite for successful immune cell entry to the brain (2011) (225)
- A Transmembrane Tight Junction Protein Selectively Expressed on Endothelial Cells and Platelets* (2002) (225)
- Involvement of the choroid plexus in central nervous system inflammation (2001) (224)
- Lymphocyte Targeting of the Central Nervous System: A Review of Afferent and Efferent CNS‐Immune Pathways (1996) (220)
- Novel insights into the development and maintenance of the blood–brain barrier (2014) (220)
- Brain Infiltration of Leukocytes Contributes to the Pathophysiology of Temporal Lobe Epilepsy (2011) (220)
- Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. (2009) (215)
- Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood–Brain Barrier Endothelium (2010) (214)
- Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood‐brain barrier suggests their involvement in G‐protein‐dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis (2002) (214)
- VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF (2008) (209)
- Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease (2018) (206)
- Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle (2011) (200)
- The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin. (1998) (197)
- The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury (2012) (196)
- E- and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis. (1997) (193)
- Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke. (2016) (188)
- Estrogen Receptor α Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis (2011) (179)
- Claudin-1, claudin-2 and claudin-11 are present in tight junctions of choroid plexus epithelium of the mouse (2001) (171)
- Immune cell entry into the central nervous system: Involvement of adhesion molecules and chemokines (2008) (169)
- Tight junctions in brain barriers during central nervous system inflammation. (2011) (167)
- Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases (2014) (165)
- Dysferlin Is a New Marker for Leaky Brain Blood Vessels in Multiple Sclerosis (2006) (162)
- T‐cell trafficking in the central nervous system (2012) (160)
- T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells. (2003) (156)
- Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody (1992) (155)
- Intracellular Domain of Brain Endothelial Intercellular Adhesion Molecule-1 Is Essential for T Lymphocyte-Mediated Signaling and Migration1 (2003) (151)
- Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts (2004) (144)
- A dominant mutant of occludin disrupts tight junction structure and function. (1999) (142)
- Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro (2000) (142)
- Mouse CD99 participates in T-cell recruitment into inflamed skin. (2004) (140)
- The blood-central nervous system barriers actively control immune cell entry into the central nervous system. (2008) (140)
- Culture-Induced Changes in Blood—Brain Barrier Transcriptome: Implications for Amino-Acid Transporters in vivo (2009) (139)
- Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro (1990) (139)
- Loss of astrocyte polarity marks blood–brain barrier impairment during experimental autoimmune encephalomyelitis (2009) (132)
- Importance of integrin LFA-1 deactivation for the generation of immune responses (2005) (132)
- Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness. (1999) (131)
- Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis (2011) (129)
- Wiring the Vascular Network with Neural Cues: A CNS Perspective (2015) (125)
- Cell surface levels of endothelial ICAM‐1 influence the transcellular or paracellular T‐cell diapedesis across the blood–brain barrier (2015) (125)
- β2 Integrin–Mediated Crawling on Endothelial ICAM-1 and ICAM-2 Is a Prerequisite for Transcellular Neutrophil Diapedesis across the Inflamed Blood–Brain Barrier (2014) (120)
- Natalizumab: Targeting α4-Integrins in Multiple Sclerosis (2007) (116)
- β1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity (2009) (111)
- Stroke Research Priorities for the Next Decade – A Representative View of the European Scientific Community (2006) (108)
- PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis. (2000) (105)
- E- and P-Selectin Are Not Required for the Development of Experimental Autoimmune Encephalomyelitis in C57BL/6 and SJL Mice1 (2007) (105)
- Cell adhesion molecules on vessels during inflammation in the mouse central nervous system (1994) (103)
- T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer’s disease-like cerebral amyloidosis (2016) (102)
- Immunohistochemical localization of the murine transferrin receptor (TfR) on blood–tissue barriers using a novel anti-TfR monoclonal antibody (1998) (102)
- Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis (2016) (101)
- Differentiation of blood-brain barrier endothelial cells. (1998) (98)
- Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro (2013) (97)
- Interferon‐β stabilizes barrier characteristics of brain endothelial cells in vitro (2004) (97)
- Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation (2012) (96)
- Cutting Edge: Natalizumab Blocks Adhesion but Not Initial Contact of Human T Cells to the Blood-Brain Barrier In Vivo in an Animal Model of Multiple Sclerosis1 (2009) (96)
- Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node (2008) (93)
- PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation (2019) (92)
- Comparison of Immortalized bEnd5 and Primary Mouse Brain Microvascular Endothelial Cells as in vitro Blood–Brain Barrier Models for the Study of T Cell Extravasation (2011) (91)
- Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. (2010) (90)
- Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1. (1995) (86)
- Induction of acute inflammatory lung injury by staphylococcal enterotoxin B. (1997) (85)
- The circumventricular organs participate in the immunopathogenesis of experimental autoimmune encephalomyelitis (2005) (85)
- Immunosurveillance modelled in vitro: naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium. (1997) (84)
- Ultrastructural localization of adhesion molecules in the healthy (1999) (82)
- Platelet endothelial cell adhesion molecule‐1 modulates endothelial cell motility through the small G‐protein Rho (2003) (82)
- Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH) (2017) (81)
- Migration of T Cells in Vivo: Molecular Mechanisms and Clinical Implications (2001) (80)
- Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis (2016) (79)
- Structure and Junctional Complexes of Endothelial, Epithelial and Glial Brain Barriers (2019) (78)
- Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation (2020) (76)
- Caveolin-1 opens endothelial cell junctions by targeting catenins. (2012) (75)
- The choroid plexus is a key cerebral invasion route for T cells after stroke (2017) (75)
- P-Selectin Glycoprotein Ligand 1 Is Not Required for the Development of Experimental Autoimmune Encephalomyelitis in SJL and C57BL/6 Mice1 (2005) (75)
- Encephalitogenic T cells use LFA‐1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvessels in vivo (2002) (75)
- T cell migration into the central nervous system during health and disease: Different molecular keys allow access to different central nervous system compartments (2010) (73)
- T cell interaction with ICAM-1-deficient endothelium in vitro: transendothelial migration of different T cell populations is mediated by endothelial ICAM-1 and ICAM-2. (1999) (72)
- Dual role of ALCAM in neuroinflammation and blood–brain barrier homeostasis (2017) (71)
- IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier (2008) (70)
- Regulation of immune cell entry into the central nervous system. (2006) (69)
- Ischemia–reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function (2018) (69)
- ICAMs support B cell interactions with T follicular helper cells and promote clonal selection (2017) (67)
- Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha. (2003) (66)
- Flotillins Interact with PSGL-1 in Neutrophils and, upon Stimulation, Rapidly Organize into Membrane Domains Subsequently Accumulating in the Uropod (2009) (63)
- Ligand-induced adhesion to activated endothelium and to vascular cell adhesion molecule-1 in lymphocytes transfected with the N-formyl peptide receptor. (1994) (62)
- Adhesion molecule phenotype of T lymphocytes in inflamed CNS (1998) (61)
- Functions of lipid raft membrane microdomains at the blood–brain barrier (2009) (60)
- Claudin-3-deficient C57BL/6J mice display intact brain barriers (2019) (59)
- Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines (2008) (58)
- Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. (2015) (58)
- Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. (2004) (57)
- Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitors (2000) (56)
- α4β1 Integrin Mediates the Recruitment of Immature Dendritic Cells across the Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis (2010) (54)
- DARC shuttles inflammatory chemokines across the blood–brain barrier during autoimmune central nervous system inflammation (2014) (53)
- Interaction of T Lymphocytes with Cerebral Endothelial Cells in vitro (1991) (53)
- Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke (2018) (51)
- Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo (2013) (49)
- Interferon-β stabilizes barrier characteristics of the blood–brain barrier in four different species in vitro (2008) (48)
- The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions (2014) (47)
- Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells (2013) (46)
- Isolation and molecular characterization of brain microvascular endothelial cells from human brain tumors (2002) (45)
- Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro (2020) (44)
- Investigation of leptomeningeal enhancement in MS (2015) (44)
- ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier (2017) (43)
- Gene and Protein Expression Profiling of the Microvascular Compartment in Experimental Autoimmune Encephalomyelitis in C57BI/6 and SJL Mice (2005) (43)
- Soluble and cell surface ICAM‐1 as markers for disease activity in multiple sclerosis (1998) (42)
- Going Against the Tide – How Encephalitogenic T Cells Breach the Blood-Brain Barrier (2012) (41)
- Postarrest stalling rather than crawling favors CD8+ over CD4+ T‐cell migration across the blood–brain barrier under flow in vitro (2016) (40)
- A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow (2018) (38)
- Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T‐cell homing into the CNS (2010) (38)
- Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1‐integrin (2015) (38)
- Claudin-12 is not required for blood–brain barrier tight junction function (2019) (38)
- PSGL‐1 and E/P‐selectins are essential for T‐cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE (2014) (37)
- Serum cytokine levels do not correlate with disease activity and severity assessed by brain MRI in multiple sclerosis (2002) (36)
- Polyoma virus middle‐T‐transformed PECAM‐1 deficient mouse brain endothelial cells proliferate rapidly in culture and form hemangiomas in mice (2005) (35)
- Building up the blood-brain barrier (2003) (35)
- Immunotherapy of experimental autoimmune encephalomyelitis (EAE): differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis rat. (1989) (35)
- Glycosylation processing inhibition by castanospermine prevents experimental autoimmune encephalomyelitis by interference with IL-2 receptor signal transduction (2002) (33)
- Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV‐induced meningitis (2016) (32)
- Junctional Adhesion Molecule (JAM)-C Deficient C57BL/6 Mice Develop a Severe Hydrocephalus (2012) (32)
- Brain barriers in health and disease (2017) (30)
- Migration of immature mouse DC across resting endothelium is mediated by ICAM‐2 but independent of β2‐integrins and murine DC‐SIGN homologues (2006) (30)
- Therapeutic targeting of α4‐integrins in chronic inflammatory diseases: tipping the scales of risk towards benefit? (2005) (28)
- Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions (2020) (27)
- TET inducible expression of the α4β7‐integrin ligand MAdCAM‐1 on the blood–brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis (2011) (27)
- β1-Integrin/Matrix Interactions Support Blood–Brain Barrier Integrity (2011) (27)
- COVID-19 and the Vasculature: Current Aspects and Long-Term Consequences (2022) (26)
- Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis (2020) (26)
- Brain endothelial PPARγ controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro (2007) (26)
- How Does the Immune System Enter the Brain? (2022) (25)
- Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells (2020) (25)
- Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice (2014) (24)
- Cell surface bound and soluble adhesion molecules in CSF and blood in multiple sclerosis: correlation with MRI-measures of subclinical disease severity and activity (2002) (24)
- Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier (2021) (24)
- A Novel Cervical Spinal Cord Window Preparation Allows for Two-Photon Imaging of T-Cell Interactions with the Cervical Spinal Cord Microvasculature during Experimental Autoimmune Encephalomyelitis (2017) (24)
- CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. (2020) (23)
- Refined clinical scoring in comparative EAE studies does not enhance the chance to observe statistically significant differences (2016) (23)
- Effect of interferon-β and atorvastatin on Th1/Th2 cytokines in multiple sclerosis (2008) (23)
- Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. (2008) (22)
- Modeling immune functions of the mouse blood–cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier (2015) (22)
- T Cell‐Mediated Transport of Polymer Nanoparticles across the Blood–Brain Barrier (2020) (22)
- Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study- (2017) (22)
- Role of glucocorticoids on T cell recruitment across the blood-brain barrier (2000) (22)
- The LPS Receptor, CD14 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis (2006) (21)
- Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS (2020) (20)
- L‐Selectin‐deficient SJL and C57BL/6 mice are not resistant to experimental autoimmune encephalomyelitis (2008) (19)
- Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments (2016) (19)
- Non-invasive near-infrared fluorescence imaging of the neutrophil response in a mouse model of transient cerebral ischaemia (2016) (19)
- Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome (2021) (19)
- Impaired T-cell migration to the CNS under fingolimod and dimethyl fumarate (2017) (19)
- Therapeutic targeting of leukocyte trafficking across the blood-brain barrier. (2007) (18)
- Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis. (2022) (17)
- Leptomeningeal contrast enhancement and blood-CSF barrier dysfunction in aseptic meningitis (2015) (16)
- Lung ICAM‐1 and ICAM‐2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin‐inflamed lungs (2016) (16)
- Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro. (2007) (15)
- Interferon-β1b leads to a short-term increase of soluble but long-term stabilisation of cell surface bound adhesion molecules in multiple sclerosis (2004) (15)
- Transfer of the sFLT-1 Gene in Morris Hepatoma Results in Decreased Growth and Perfusion and Induction of Genes Associated with Stress Response (2005) (15)
- Soluble and cell surface ICAM‐3 in blood and cerebrospinal fluid of patients with multiple sclerosis: influence of methylprednisolone treatment and relevance as markers for disease activity (2000) (15)
- Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis (2018) (15)
- Development of the Blood-Brain Interface (2007) (14)
- Novel mechanisms of the transendothelial migration of leukocytes. (2001) (14)
- Nano-scale architecture of blood-brain barrier tight-junctions (2020) (14)
- Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod (2018) (14)
- CD45RA+ ICAM‐3+ lymphocytesin cerebrospinal fluid and blood as markers of disease activity in patients with multiple sclerosis (2000) (14)
- Detection of endothelial/lymphocyte interaction in spinal cord microvasculature by intravital videomicroscopy. (2003) (14)
- The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis. (2006) (13)
- Blood-Brain Barrier Differentiation (2011) (13)
- The Role of α4-Integrin in T Lymphocyte Migration Into the Inflamed and Noninflamed Central Nervous System (1998) (12)
- The Blood-Brain Barrier in EAE (2005) (12)
- Involvement of tight junctions during transendothelial migration of mononuclear cells in experimental autoimmune encephalomyelitis. (2004) (12)
- Leukocyte Trafficking: Molecular Mechanisms, Therapeutic Targets, and Methods (2005) (12)
- Sleep enhances numbers and function of monocytes and improves bacterial infection outcome in mice (2020) (12)
- ICAM-1null C57BL/6 Mice Are Not Protected from Experimental Ischemic Stroke (2018) (11)
- Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis (2021) (11)
- Advancing brain barriers RNA sequencing: guidelines from experimental design to publication (2020) (10)
- Angiostatin overexpression in Morris hepatoma results in decreased tumor growth but increased perfusion and vascularization. (2006) (10)
- Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance (2022) (10)
- Innovative high-resolution microCT imaging of animal brain vasculature (2020) (10)
- PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice (2011) (9)
- Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis (2021) (9)
- Editorial: PSGL‐1—the hidden player in T cell trafficking into the brain in multiple sclerosis? (2009) (9)
- The role of alpha 4-integrin in T lymphocyte migration into the inflamed and noninflamed central nervous system. (1998) (9)
- IL-10 and its homologs: important immune mediators and emerging immunotherapeutic agents (2001) (8)
- TNFα blockade mediates bone protection in antigen-induced arthritis by reducing osteoclast precursor supply. (2018) (8)
- Factors influencing patient satisfaction with the first diagnostic consultation in multiple sclerosis: a Swiss Multiple Sclerosis Registry (SMSR) study (2019) (8)
- Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells (2021) (8)
- VivoFollow 2: Distortion-Free Multiphoton Intravital Imaging (2020) (8)
- Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis (2020) (8)
- Cluster: barriers of the central nervous system (2018) (8)
- The blood–CSF–brain route of neurological disease: The indirect pathway into the brain (2021) (7)
- CD49d/CD29‐integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation (2019) (7)
- ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro (2021) (7)
- CD45RA+ ICAM‐3+ lymphocytes in interferon‐β1b‐treated and ‐untreated patients with relapsing–remitting multiple sclerosis (2004) (7)
- Distinct migratory pattern of naive and effector T cells through the blood–CSF barrier following Echovirus 30 infection (2019) (7)
- Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers (2017) (6)
- Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis (2020) (6)
- The Modular µSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro (2022) (6)
- Immune cell migration across the blood–brain barrier: molecular mechanisms and therapeutic targeting (2006) (5)
- Lysis of rat brain microvascular endothelial cells mediated by resting but not activated MBP-specific CD4+ T cell lines (1994) (5)
- Preclinical testing of strategies for therapeutic targeting of human T-cell trafficking in vivo. (2010) (5)
- Biotin-NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes. (2021) (5)
- Pharmacological Inhibition of Acid Sphingomyelinase Ameliorates Experimental Autoimmune Encephalomyelitis. (2019) (5)
- Oligomeric Forms of Human Amyloid-Beta(1–42) Inhibit Antigen Presentation (2020) (5)
- Full spectrum of vitamin D immunomodulation in multiple sclerosis: mechanisms and therapeutic implications (2022) (5)
- Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. (2021) (4)
- Brain Barriers and Multiple Sclerosis: Novel Treatment Approaches from a Brain Barriers Perspective. (2020) (4)
- α4-integrins: structure, function and secrets (2007) (4)
- Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo. (2019) (4)
- Soluble and Cell Surface Bound Adhesion Molecules in Blood and Cerebrospinal Fluid as Diagnostic Markers and Parameters for Disease Activity, Disease Severity and Treatment Efficacy in Patients with Multiple Sclerosis. Lösliche und Zelloberflächen-gebundene Adhäsionsmoleküle in Blut und Liquor cereb (2001) (4)
- Perivascular spaces and their role in neuroinflammation (2022) (4)
- Covalent and Noncovalent Conjugation of Degradable Polymer Nanoparticles to T Lymphocytes. (2021) (4)
- Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation (2022) (4)
- Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions (2021) (4)
- Investigation of Molecular Mechanisms Involved in T Lymphocyte Recruitment across the Blood-Spinal Cord and Brain Barriers in Health and Disease (2004) (3)
- Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine Liver (2021) (3)
- FACS Analysis of Endothelial Cells (2004) (3)
- Private immune protection at the border of the central nervous system (2021) (3)
- Endothelium Brain Barrier - rawling on Blood Cell Arrest, Polarization, and Directed C ICAM-2, and VCAM-1 in Shear-Resistant T Differential Roles for Endothelial ICAM-1, (2010) (3)
- Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes (2022) (3)
- Microglia Get a Little Help from "Th"-eir Friends. (2020) (2)
- The Genetic Background of Mice Influences the Effects of Cigarette Smoke on Onset and Severity of Experimental Autoimmune Encephalomyelitis (2019) (2)
- Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus (2020) (2)
- Diapedesis across the Inflamed Blood Prerequisite for Transcellular Neutrophil Endothelial ICAM-1 and ICAM-2 Is a Mediated Crawling on − Integrin 2 β (2013) (1)
- Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo (2013) (1)
- Loss of astrocyte polarity marks blood–brain barrier impairment during experimental autoimmune encephalomyelitis (2009) (1)
- UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices (2023) (1)
- Adhesion and Signalling Molecules Controlling the Extravasation of Leukocytes across the Endothelium (2008) (1)
- Direct In Vivo Evidence for α4-Integrin Mediated Interaction of Encephalitogenic T Cell Blasts with Endothelial VCAM-1 in the Spinal Cord White Matter Using Intravital Fluorescence Videomicroscopy (2001) (1)
- Encephalomyelitis in SJL and C57BL/6 Mice Experimental Autoimmune Required for the Development of P-Selectin Glycoprotein Ligand 1 Is Not (2005) (1)
- Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH) (2016) (1)
- The circumventricular organs are involved in inflammation in the central nervous system (1998) (1)
- Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown (2021) (1)
- Multiple sclerosis: Immunopathological heterogeneity and its implications (2022) (1)
- Maternal Infection Impairs Fetal Brain Development via Choroid Plexus Inflammation. (2020) (1)
- Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro (2004) (1)
- SP0091 E-selectin deletion constructs allow the study of differential binding of mononuclear and polymorphonuclear leukocytes to e-selectin in inflammation (2001) (0)
- NOVEL OXAZOLO-OXAZOLE DERIVATIVES OF FINGOLIMOD INDUCE LYMPHOPENIA AND REDUCE SYMPTOMS OF EAE IN MICE (2018) (0)
- Enhanced T cell transmigration across murine liver sinusoidal endothelium is mediated by transcytosis and surface presention of chemokines (2008) (0)
- Advancing brain barriers RNA sequencing: guidelines from experimental design to publication (2020) (0)
- Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers (2017) (0)
- Two-photon imaging of T-cell interactions with the inflamed cervical spinal cord microvasculature (2017) (0)
- Stalling Instead of Crawling Allows CD8+ T cells to Cross the Blood-BrainBarrier (2017) (0)
- Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves. (2023) (0)
- Signaling and Migration Essential for T Lymphocyte-Mediated Intercellular Adhesion Molecule-1 Is Intracellular Domain of Brain Endothelial (2003) (0)
- In memoriam, Roy Weller (1938–2022) (2022) (0)
- SYMPOSIUM: 17th Key Symposium: Blood‐Brain Barrier: Key to Brain Health and Disease (2022) (0)
- Society for Microcirculation and Vascular Biology (GfMVB) / Swiss Society for Microcirculation (SSM): Joint Meeting 2009, Bern, October 2009: Program and Abstracts (2009) (0)
- Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells (2020) (0)
- Distinct migratory pattern of naive and effector T cells through the blood–CSF barrier following Echovirus 30 infection (2019) (0)
- T cell migration into the CNS during health and disease: Different molecular keys allow access to different CNS compartments (2010) (0)
- Mouse CD99 is required for transendothelial migration of T cells (2004) (0)
- Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers (2019) (0)
- In Vitro Transendothelial Migration Assay (2006) (0)
- Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell-Mediated Neuroinflammation. (2023) (0)
- The Caporetto Disaster (0)
- The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions (2014) (0)
- Alpha4beta1 but not alpha4beta7 is critically involved in the development of EAE in the SJL/J mouse Evidence for a role in T cell migration and activation (1998) (0)
- Encephalomyelitis in C 57 BL / 6 and SJL Mice Development of Experimental Autoimmune E-and P-Selectin Are Not Required for the Deutsch and (2007) (0)
- Neuroinflammatory Diseases Barrier Disruption in Demyelinating Spinal Cord - Neutrophils Mediate Blood (2014) (0)
- Molecular mechanisms of immune cell migration across the blood–brain barrier (2012) (0)
- Pioglitazone reduces the transmigratory capacity of activated T cells in an in-vitro model of the blood-brain-barrier (2005) (0)
- cq[~ is Critically Involved in the Development of EAE in the SJL/J Mouse: Evidence for a Role in T Cell Migration and Activation (2018) (0)
- A mouse model for paraneoplastic neurological syndrome: From anti-tumor immunity to autoimmunity targeting neurons (2014) (0)
- Cover Picture: Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node – Eur. J. Immunol. 8/2008 (2008) (0)
- THU0069 Effects of Anti-TNF-Alpha Therapy on the Recruitment and Availability of Osteoclast Precursors in a Model of Rheumatoid Arthritis (2015) (0)
- Optimal liver metabolism and proliferation require the tight junction protein claudin-3 (2020) (0)
- Modeling Brain Vasculature Immune Interactions In Vitro. (2022) (0)
- Bovine neutrophil chemotaxis to Listeria monocytogenes in neurolisteriosis depends on microglia-released rather than bacterial factors (2022) (0)
- Modeling immune functions of the mouse blood–cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier (2015) (0)
- Insulin-like growth factor-1 receptor controls the function of CNS-resident macrophages and their contribution to neuroinflammation (2023) (0)
- Introduction (0)
- β-catenin transcriptional activity improves impedance of bEnd5 cells A–D. (2013) (0)
- Blockade of VEGFR3 signaling leads to functional impairment of dural lymphatic vessels without affecting autoimmune neuroinflammation (2023) (0)
- Defining the roles of ICAM-1 and ICAM-2 in the pathogenesis of experimental autoimmune encephalomyelitis (2014) (0)
- JCB_201412147 1..14 (2015) (0)
- Macrophages clear the way for CNS fluid flow (2023) (0)
- 2-31-22 Soluble and cellular ICAM-1 as a activity parameter in multiple sclerosis (1997) (0)
- Involvement of junctional adhesion molecules in the pathogenesis of experimental autoimmune encephalomyelitis (2014) (0)
- Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor (2019) (0)
- ORIGINAL RESEARCH Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine Liver Q1 Claudin-3 knockout (2021) (0)
- Private protection at the brain’s border (2021) (0)
- The brain barriers as therapeutic targets in neuroinflammation (2013) (0)
- Novel insights into the development and maintenance of the blood–brain barrier (2014) (0)
- The choroid plexus in brain lymphocyte invasion after stroke (2016) (0)
- Claudin-3-deficient C57BL/6J mice display intact brain barriers (2019) (0)
- Identification of subset specific mechanisms for CD8+ versus CD4+ TEM cells mediating their migration across the inflamed blood–brain barrier under physiological flow in vitro (2014) (0)
- ICAM-1null C57BL/6 Mice Are Not Protected from Experimental Ischemic Stroke (2018) (0)
- Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis (2020) (0)
- Negotiating the brain barriers: Access of immune cells and pathogens into the CNS (2010) (0)
- A Novel Cervical Spinal Cord Window Preparation Allows for Two-Photon Imaging of T-Cell Interactions with the Cervical Spinal Cord Microvasculature During EAE (2017) (0)
- Brain barriers virtual: an interim solution or future opportunity? (2022) (0)
- DARC shuttles inflammatory chemokines across the blood–brain barrier during autoimmune central nervous system inflammation (0)
- Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study- (2017) (0)
- Foreword (0)
- Contents Vol. 49, 2012 (2012) (0)
- 518 LIVER ENDOTHELIAL CELLS ENHANCE THE BIOLOGICAL EFFECT OF CXCL9 AND CXCL12 BY UPTAKE AND SURFACE PRESENTATION (2008) (0)
- Latest Publications in Cytometry Part A You Should Not Miss (2008) (0)
- EUSI-ESO News (2008) (0)
- Inhalt Band 35, Heft 2, April 2008 (2008) (0)
- Negotiating the brain barriers (2010) (0)
- α4β1 but not α4β7 is critically involved in the development of EAE in the SJL/J mouse: Evidence for a role in T cell migration and activation (1998) (0)
- Molecular mechanisms and anatomical routes of immune cell entry into the central nervous system (2012) (0)
- A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature (2022) (0)
- alpha4beta1 is a major molecular cue used by cytotoxic CD8 T cells to migrate into the CNS (2014) (0)
- Oligomeric amyloid‐beta 1–42 inhibits antigen presentation (2020) (0)
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What Schools Are Affiliated With Britta Engelhardt?
Britta Engelhardt is affiliated with the following schools:
