Bruce A. Sullenger
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Why Is Bruce A. Sullenger Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bruce Alan Sullenger is the Joseph W. and Dorothy W. Beard Professor of Experimental Surgery at the Duke University School of Medicine, the Founding Director of the Duke Translational Research Institute which he led from 2006-2016, and the Associate Director for Translation in the Duke Cancer Institute .
Bruce A. Sullenger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras (2006) (945)
- Aptamers: an emerging class of therapeutics. (2005) (858)
- Notch Promotes Radioresistance of Glioma Stem Cells (2009) (612)
- In vivo activity of nuclease-resistant siRNAs. (2004) (530)
- RNA aptamers as reversible antagonists of coagulation factor IXa (2002) (492)
- Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication (1990) (422)
- Antidote-mediated control of an anticoagulant aptamer in vivo (2004) (306)
- Emerging clinical applications of RNA (2002) (302)
- Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. (2008) (263)
- Developing aptamers into therapeutics. (2000) (263)
- Ribozyme-mediated repair of defective mRNA by targeted trans-splicing (1994) (252)
- Generation of species cross-reactive aptamers using "toggle" SELEX. (2001) (243)
- Aptamers as Therapeutics. (2017) (240)
- In vivo selection of tumor-targeting RNA motifs (2009) (221)
- From the RNA world to the clinic (2016) (207)
- Gene therapy progress and prospects: RNA aptamers (2007) (205)
- Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. (2000) (205)
- Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. (1993) (198)
- Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. (1989) (195)
- Ribozyme-Mediated Repair of Sickle β-Globin mRNAs in Erythrocyte Precursors (1998) (187)
- Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer (2015) (181)
- Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity. (2003) (174)
- Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2 (2003) (167)
- Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. (2008) (158)
- Crystal structure of an RNA aptamer bound to thrombin. (2008) (150)
- Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation (1991) (142)
- RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. (2009) (134)
- Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. (2000) (128)
- Tagging ribozyme reaction sites to follow trans–splicing in mammalian cells (1996) (116)
- Notch signaling in cancer stem cells. (2012) (114)
- Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing (2003) (114)
- The potential of aptamers as anticoagulants. (2005) (105)
- Development of universal antidotes to control aptamer activity (2009) (104)
- Nucleic acid-binding polymers as anti-inflammatory agents (2011) (101)
- Nucleic acid scavengers inhibit thrombosis without increasing bleeding (2012) (98)
- Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells. (1992) (98)
- Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells. (2012) (97)
- Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies (1997) (96)
- Blocking the Initiation of Coagulation by RNA Aptamers to Factor VIIa (2000) (89)
- Inhibiting the intrinsic pathway of coagulation with a factor XII–targeting RNA aptamer (2013) (88)
- Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication (1990) (83)
- Functional repair of a mutant chloride channel using a trans-splicing ribozyme. (2002) (82)
- Tunable cytotoxic aptamer–drug conjugates for the treatment of prostate cancer (2018) (81)
- Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis (2009) (79)
- Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. (1995) (79)
- A novel antidote-controlled anticoagulant reduces thrombin generation and inflammation and improves cardiac function in cardiopulmonary bypass surgery. (2006) (75)
- Ribozyme-mediated induction of apoptosis in human cancer cells by targeted repair of mutant p53 RNA. (2004) (74)
- Targeted inhibition of αvβ3 integrin with an RNA aptamer impairs endothelial cell growth and survival (2005) (71)
- Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function (1996) (70)
- Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. (2002) (70)
- Antidote-controlled platelet inhibition targeting von Willebrand factor with aptamers. (2007) (68)
- Efficient and specific repair of sickle β-globin RNA by trans-splicing ribozymes (2003) (64)
- RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin. (2008) (63)
- Simultaneous generation of aptamers to multiple gamma-carboxyglutamic acid proteins from a focused aptamer library using DeSELEX and convergent selection. (2007) (60)
- Design of therapeutic biomaterials to control inflammation (2022) (59)
- Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. (2012) (59)
- Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. (2008) (58)
- Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors. (1998) (57)
- Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. (2012) (57)
- A high affinity, antidote‐controllable prothrombin and thrombin‐binding RNA aptamer inhibits thrombin generation and thrombin activity (2012) (57)
- Ischemic stroke in COVID-19-positive patients: an overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist (2020) (57)
- Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin. (2009) (56)
- Conformationally Selective RNA Aptamers Allosterically Modulate the β2-Adrenoceptor (2016) (56)
- The many faces of the contact pathway and their role in thrombosis (2011) (53)
- Evaluating and enhancing ribozyme reaction efficiency in mammalian cells (1997) (52)
- Ribozyme-mediated revision of RNA and DNA. (2003) (52)
- Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics (2010) (51)
- Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40. (2013) (50)
- A hybrid DNA aptamer-dendrimer nanomaterial for targeted cell labeling. (2009) (50)
- H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity (2006) (47)
- Scavenging nucleic acid debris to combat autoimmunity and infectious disease (2016) (47)
- In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9 (2016) (46)
- Aptamers in immunotherapy. (2008) (44)
- Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis. (2017) (43)
- Antimetastatic potential of PAI-1-specific RNA aptamers. (2009) (42)
- Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers. (2019) (41)
- Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass (2018) (41)
- Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia (2007) (41)
- Targeted Disruption of β-Arrestin 2-Mediated Signaling Pathways by Aptamer Chimeras Leads to Inhibition of Leukemic Cell Growth (2014) (40)
- Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen‐specific T‐cell responses (2008) (40)
- In vivo reprogramming of hTERT by trans-splicing ribozyme to target tumor cells. (2008) (40)
- RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. (2008) (39)
- Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels. (2019) (39)
- Isolation of a nuclease-resistant decoy RNA that selectively blocks autoantibody binding to insulin receptors on human lymphocytes (1996) (38)
- Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures. (2012) (38)
- Generation and characterization of aptamers targeting factor XIa. (2017) (38)
- An Anticoagulant RNA Aptamer That Inhibits Proteinase-Cofactor Interactions within Prothrombinase* (2009) (37)
- 2'Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors. (2016) (37)
- Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis. (2018) (36)
- Enhancing RNA repair efficiency by combining trans-splicing ribozymes that recognize different accessible sites on a target RNA. (2000) (35)
- Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes. (2003) (34)
- RNA aptamer to thrombin binds anion‐binding exosite‐2 and alters protease inhibition by heparin‐binding serpins (2004) (33)
- Nucleic acid aptamers in therapeutic anticoagulation (2005) (32)
- Retargeting mobile group II introns to repair mutant genes. (2005) (31)
- Potent Anticoagulant Aptamer Directed against Factor IXa Blocks Macromolecular Substrate Interaction* (2012) (28)
- The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides (2010) (27)
- RNA repair: a novel approach to gene therapy. (2000) (26)
- Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. (2005) (26)
- Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test (2021) (26)
- Targeted genetic repair: an emerging approach to genetic therapy. (2003) (26)
- Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant. (2016) (25)
- Modulation of the Coagulation Cascade Using Aptamers (2015) (25)
- Further characterization of the target of a potential aptamer biomarker for pancreatic cancer: cyclophilin B and its posttranslational modifications. (2013) (24)
- Optimizing the substrate specificity of a group I intron ribozyme. (1999) (24)
- Translation and Clinical Development of Antithrombotic Aptamers. (2016) (24)
- Using 5'-PTMs to repair mutant beta-globin transcripts. (2007) (24)
- Evaluating Group I Intron Catalytic Efficiency in Mammalian Cells (1999) (24)
- The Inhibition of Anti-DNA Binding to DNA by Nucleic Acid Binding Polymers (2012) (23)
- Antidote control of aptamer therapeutics: the road to a safer class of drug agents. (2012) (23)
- DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists (2022) (22)
- A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function (2008) (21)
- Nucleic Acid Scavenging Polymers Inhibit Extracellular DNA-Mediated Innate Immune Activation without Inhibiting Anti-Viral Responses (2013) (20)
- Emerging applications of aptamers for anticoagulation and hemostasis (2018) (20)
- Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor. (2012) (19)
- Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking (2009) (18)
- Translating Nucleic Acid Aptamers to Antithrombotic Drugs in Cardiovascular Medicine (2010) (17)
- Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack (2012) (17)
- NF-κB inhibition by an adenovirus expressed aptamer sensitizes TNFα-induced apoptosis (2007) (17)
- A kallikrein‐targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release (2017) (16)
- Probing the interplay between the two steps of group I intron splicing: competition of exogenous guanosine with omega G. (1998) (16)
- Revising messages traveling along the cellular information superhighway. (1995) (16)
- Multivalent 4-1 BB binding aptamers costimulate CD 8 + T cells and inhibit tumor growth in mice (2007) (16)
- AIDS and HIV infection. (1995) (15)
- Colocalizing ribozymes with substrate rnas to increase their efficacy as gene inhibitors (1995) (14)
- RNA aptamer therapy for vaso-occlusion in sickle cell disease. (2011) (14)
- NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosis. (2007) (14)
- The Nucleic Acid Scavenger Polyamidoamine Third-Generation Dendrimer Inhibits Fibroblast Activation and Granulation Tissue Contraction (2014) (14)
- Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer. (2020) (13)
- Effects of plasminogen activator inhibitor-1-specific RNA aptamers on cell adhesion, motility, and tube formation. (2011) (13)
- Probing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation. (2014) (13)
- Polycationic Nanofibers for Nucleic Acid Scavenging. (2016) (11)
- Catalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biological function (2000) (11)
- Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State. (2019) (11)
- Histone Deacetylase 7 Inhibition in A Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury. (2020) (10)
- Abstract B18: Development of novel therapeutic splice-switching oligonucleotides against aggressive prostate cancer in men of African descent (2016) (10)
- Enhancing cardiac reprogramming via synthetic RNA oligonucleotides (2020) (10)
- Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs. (2017) (10)
- IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages (2021) (10)
- Proximity-dependent and proximity-independent trans-splicing in mammalian cells. (2008) (9)
- A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage. (2011) (9)
- An Aptamer for Broad Cancer Targeting and Therapy (2020) (9)
- Aptamers to Proteins (2006) (8)
- Rapid test to assess the escape of SARS-CoV-2 variants of concern (2021) (8)
- Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury. (2018) (8)
- Therapeutic Aptamers: Evolving to Find Their Clinical Niche. (2020) (8)
- Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy. (2007) (8)
- The effect of surface contact activation and temperature on plasma coagulation with an RNA aptamer directed against factor IXa (2012) (8)
- An in vitro system for efficiently evaluating gene therapy approaches to hemoglobinopathies (2000) (8)
- Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects (2021) (7)
- Antithrombotic Therapy in Acute Coronary Syndrome: How Far Up the Coagulation Cascade Will We Go? (2010) (7)
- Therapeutic aptamers and antidotes: a novel approach to safer drug design. (2003) (7)
- Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. (2016) (6)
- RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells. (2015) (6)
- Toll-like receptor activation as a biomarker in traumatically injured patients. (2018) (6)
- Regulatable aptamers in medicine: focus on antithrombotic strategies (2004) (6)
- Ribozyme-mediated repair of RNAs encoding mutant tumor suppressors. (1996) (6)
- Aptamers Coming of Age at Twenty-Five. (2016) (5)
- RNA repair as a novel to genetic therapy (1999) (5)
- Alternative approaches for the application of ribozymes as gene therapies for retroviral infections. (1995) (5)
- PEG‐Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response (2022) (5)
- Antidote‐Controlled Antithrombotic Therapy Targeting Factor IXa and Von Willebrand Factor (2009) (5)
- Aptamer-based factor IXa inhibition preserves hemostasis and prevents thrombosis in a piglet model of ECMO (2021) (4)
- Trans-splicing reactions by ribozymes. (1997) (4)
- Riboswitches--to kill or save the messenger. (2004) (4)
- 83. Cell_Type Specific Delivery of siRNAs with Aptamer_siRNA Chimeras (2006) (3)
- From the RNAworld to the clinic (2016) (3)
- Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples (2022) (3)
- β-Cyclodextrin-containing Polymer Treatment of Cutaneous Lupus and Influenza Improves Outcomes. (2021) (3)
- Using 59-PTMs to repair mutant b-globin transcripts (2007) (3)
- Multiplexed, quantitative serological profiling of COVID-19 from a drop of blood by a point-of-care test (2020) (3)
- Immobilization of nucleic acid binding polymers as anti-inflammatory agent in autoimmunity. (2015) (3)
- RGEN Editing of RNA and DNA: The Long and Winding Road from Catalytic RNAs to CRISPR to the Clinic (2020) (3)
- Abstract 5523: A novel aptamer targeting agent for prostate cancer (2015) (2)
- Blocking Adhesion of Sickle Erythrocytes to Endothelial P-Selectin Using an RNA Aptamer. (2007) (2)
- Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study (2022) (2)
- Targeting DAMPs with Nucleic Acid Scavengers to Treat Lupus. (2022) (2)
- Histone Deacetylase 7 In Murine Gram-Negative Acute Lung Injury. (2020) (2)
- Aptamers in the clinic (2009) (2)
- Combining Heparin and a FX/Xa Aptamer to Reduce Thrombin Generation in Cardiopulmonary Bypass and COVID-19. (2022) (2)
- 66. Identification and Characterization of a B Cell Aptamer That Targets Diffuse Large B Cell Lymphoma (DLBCL) and Chronic Myelogenous Leukemia (CML) (2015) (2)
- Aptamers in Bordeaux, 24–25 June 2016 (2017) (1)
- Ribozyme-Mediated Repair of Mutant p53 Transcripts in Breast Cancer Cells (1998) (1)
- Tumor targeting aptamers identified by in vivo SELEX (2008) (1)
- Exposure and Outcome in practice: a retrospective cohort study between fibrinolytic suppression and hypercoagulability, the severity of hypoxemia, and mortality in COVID-19 patients. (2022) (1)
- Age and Comorbidities Predict COVID-19 Outcome, Regardless of Innate Immune Response Severity: A Single Institutional Cohort Study (2022) (1)
- Key Pathogenic Factors in Coronavirus Disease 2019–Associated Coagulopathy and Acute Lung Injury Highlighted in a Patient With Copresentation of Acute Myelocytic Leukemia: A Case Report (2021) (1)
- Nucleic-Acid Scavengers Mitigate Breast Cancer Induced Inflammation, Invasion, and Metastasis (2020) (1)
- Abstract WP99: Reversible VWF Inhibitor Reduces Stroke Volumes Compared to TPA in Canine Model of Large Vessel Occlusion Stroke (2020) (1)
- Gene Therapy Applications of Ribozymes (2003) (1)
- Innovative Drug Design Using RNA Aptamers for Various Anaemias (2007) (1)
- Rapid molecular imaging of active thrombi in vivo using aptamer-antidote probes (2023) (1)
- Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer (2023) (1)
- Something old, something new. (2011) (1)
- RNA repair as a novel approach to genetic therapy. (1999) (1)
- 65. A Novel Aptamer Targeting Agent for Prostate Cancer (2015) (1)
- Abstract A90: Blocking proinvasive signaling and inflammatory activation in triple-negative breast cancer with nucleic-acid scavengers (NAS) (2020) (0)
- X-Ray Structure of an Anticoagulant RNA Aptamer Bound to Factor Xa. Structural Basis for Its Ability to Disrupt Interactions Between Xa and Va within Prothrombinase (2014) (0)
- Abstract P102: Elevated Von Willebrand Factor in Patients Presenting With Large-Vessel Occlusion Stroke as First Symptom of COVID-19 Mirrors Levels in Patients With COVID-19 Requiring ICU-Level Care (2021) (0)
- 135: AGE AND COMORBIDITIES PREDICT COVID-19 OUTCOME REGARDLESS OF SEVERITY OF INNATE IMMUNE RESPONSE (2021) (0)
- Intracellular Immunization Against Hiv–a Novel Treatment Strategy For Aids (1993) (0)
- Mixed-surface polyamidoamine polymer variants retain nucleic acid-scavenger ability with reduced toxicity (2022) (0)
- Cell-Free DNA Is Elevated after Acute Arterial Injury in Infants (2016) (0)
- Aptamers and siRNAs in Cardiovascular Disease (2008) (0)
- Abstract 4189: Cationic polymer inhibits pancreatic cancer invasion and metastasis (2018) (0)
- Abstract 570: Aptamers Against Factor Xa or Thrombin Synergize With Catalytic Site Inhibitors of FXa or Thrombin, Respectively, to Effectively Anticoagulate Blood in an Ex Vivo Oxygenator Circuit (2014) (0)
- Abstract B006: Development of a novel therapeutic splice-switching oligonucleotide targeting race-related androgen receptor signaling and aggressive prostate cancer (2020) (0)
- Laboratory Assessment of Anti-Coagulant Properties of a Von Willebrand Factor Targeted Aptamer (2014) (0)
- ANTIDOTE REVERSAL OF A NOVEL ANTICOAGULANT DECREASES MORTALITY AND IMPROVES NEUROLOGICAL FUNCTION IN A MURINE MODEL OF SUBARACHNOID HEMORRHAGE (2007) (0)
- The Sabiston Vision of Basic Science in a Department of Surgery (2003) (0)
- Targeting DAMP-induced inflammation to prevent breast cancer metastasis and improve anti-tumor immunity (2019) (0)
- Blocking Complement-Mediated Hemolysis of PNH Erythrocytes by RNA Aptamers to C8 and C9. (2004) (0)
- 202. Using RNA to Inhibit Intimal Hperplasia by Blocking E2F Function (2004) (0)
- Aptamer-Small Molecule Conjugates As Potent and Reversible Surgical Anticoagulants Targeting Thrombin (2022) (0)
- Abstract 2639: Development of immunocytotoxic RNA therapeutics for human melanoma (2014) (0)
- INVERSION MÉDIÉE PAR ANTIDOTE DE COLORATION D'APTAMÈRE EXTRACELLULAIRE (2018) (0)
- 45. Molecular-based translational medicine (2008) (0)
- Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of Arterial Occlusion (2022) (0)
- Effect of PAI-1 Specific RNA Aptamers On Cell Adhesion and Motility. (2009) (0)
- Inhibition of human and pig thrombin by a high-affinity nuclease-resistant RNA aptamer (2000) (0)
- X-Ray Structure of Thrombin Bound to a Heterobifunctional Aptamer-Drug Conjugate Reveals the Mechanistic Basis for a Novel Tethered Inhibition Strategy (2022) (0)
- Abstract PR04: Development of a novel therapeutic splice-switching oligonucleotide targeting race-related androgen receptor signaling and aggressive prostate cancer (2018) (0)
- Emerging clinical applications of nucleic acids (2000) (0)
- RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit (2016) (0)
- Abstract 4903: Cationic polymer inhibits pancreatic cancer invasionin vitroand metastasisin vivo (2017) (0)
- Developing Antidote Controlled Antiplatelet Therapies By Targeting The Vwf ‐ Gp Ib‐Ix‐V Interaction (2007) (0)
- Application of SELEX in vivo identifies tumor specific RNA aptamers (2005) (0)
- In Vivo Selection of Aptamers Targeting Pancreatic Cancer (2012) (0)
- Crystal structure of an RNA aptamer bound to human thrombin (2008) (0)
- Applications and future of aptamers that achieve rapid-onset anticoagulation (2023) (0)
- 377. Developing siRNAs to the E2Fs to Control Vascular Growth and Remodeling (2005) (0)
- Applications and Future of Anticoagulant Aptamers for Surgical and Percutaneous Interventional Cardiac Procedures. (2023) (0)
- Aptamer Mediated Inhibition of Protein S (2016) (0)
- Trans-Splicing Ribozymes as Potential HIV Gene Inhibitors (1998) (0)
- Target Sites in Human Cells Group II Introns Designed to Insert into Therapeutically Relevant DNA (2013) (0)
- 272. Nucleic Acid Scavenging Nanofibers as Anti-Inflammatory Meshes (2015) (0)
- Blocking pro-invasive signaling and inflammatory activation in triple-negative breast cancer with nucleic-acid scavengers (NASs). (2020) (0)
- Histone Deacetylase 3 Associates with Key Regulators of NFkB Signaling in Human Lung Epithelial Cells under Stimulation with LPS (2020) (0)
- Exploiting RNA aptamers for cancer therapy (P4407) (2013) (0)
- An Aptamer That Rapidly Internalizes into Cancer Cells Utilizes the Transferrin Receptor Pathway (2023) (0)
- Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients (2016) (0)
- Aptamers as Rapid Onset and Rapidly Reversible Antithrombotic Agents (2019) (0)
- Abstract 1232: Development of novel therapeutic splice-switching oligonucleotides targeting oncogenic RNA isoforms driving race-related aggressive prostate cancer (2017) (0)
- O006 Role of nucleic acid-binding polymers in TLR activation and autoimmune disease development (2012) (0)
- Abstract 2817: An RNA aptamer is a potential biomarker for pancreatic cancer (2011) (0)
- 1028. Use of Antisense Oligonucleotides To Restore Activity in Mutant p53 (2006) (0)
- Blocking Complement-Mediated Hemolysis Using RNA Aptamers That Bind Complement Component C8. (2005) (0)
- Abstract 94: Randomized, Double-blind, Placebo-controlled Phase 1 Study Of Vwf-binding Aptamer, Bb-031: Safety, Tolerability, Pharmacokinetic And Pharmacodynamic Activity In Healthy Volunteers (2023) (0)
- Targeting inflammation to prevent breast cancer metastasis (2018) (0)
- 903. Group I Ribozymes and SMaRT|[trade]| as Trans-Splicing RNA Repair Therapies for |[beta]|-Globin Mutations (2004) (0)
- DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban (2018) (0)
- Abstract 305: Development of an Antidote-Controlled RNA Probe for Molecular Thrombi Imaging (2015) (0)
- Abstract P3-01-03: Modulating inflammation with nucleic acid scavengers to prevent breast cancer metastasis (2020) (0)
- DesGla-XaS195A Bound to Aptamer 11F7t (2018) (0)
- RNA & OLIGONUCLEOTIDE THERAPEUTICS (2010) (0)
- 184. In Vivo SELEX: Generation of Aptamers and Identification of Target Protein Relevant to Tumor (2009) (0)
- Abstract 16728: Translating Thrombolytic Efficacy of Von Willebrand Factor Aptamer Inhibition From a Small to Large Animal Model of Carotid Occlusion (2017) (0)
- Abstract 4515: Utilizing nucleic-acid scavengers (NASs) to inhibit proinflammatory and proinvasive signaling in triple-negative breast cancer (2019) (0)
- 611. Group I intron-mediated trans-splicing revision of mutant p53 RNA transcripts (2004) (0)
- Woodruff and Sullenger Modulation of the Coagulation Cascade Using Aptamers 2085 (0)
- Differential Transcriptomic Profiling Between Patients With Sepsis-Induced Ards And Sepsis Without Ards (2021) (0)
- Utilizing Directed Evolution to Interrogate and Optimize CRISPR/Cas Guide RNA Scaffolds (2022) (0)
- Abstract 32: Cytidine-Phosphate-Guanosine Deoxyoligonucleotides in Cutaneous Scarring (2012) (0)
- Blocking Adhesion of Sickle Erythrocytes to Endothelial αVβ3 Using RNA Aptamer. (2006) (0)
- In-vivo SELEX Against Pancreatic Cancer Xenografts (2011) (0)
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