Bruce C. Kone
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Most Influential Person
American biologist
Why Is Bruce C. Kone Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bruce C. Kone is an American professor, nephrologist and molecular biologist. He is also a United States Masters Swimming national record holder, twenty-three-time USMS national champion, and eight-time FINA Masters world's top-ranked age group swimmer. He is currently a tenured professor of medicine at the University of Texas Health Science Center at Houston .
Bruce C. Kone's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- POST‐INJURY MULTIPLE ORGAN FAILURE: THE ROLE OF THE GUT (2001) (480)
- Biosynthesis and homeostatic roles of nitric oxide in the normal kidney. (1997) (389)
- Endothelin, a peptide inhibitor of Na(+)-K(+)-ATPase in intact renaltubular epithelial cells. (1989) (282)
- Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide. (2003) (280)
- Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney. (1994) (271)
- Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. (2002) (261)
- Nitric oxide in renal health and disease. (1997) (214)
- Identification of constitutive and inducible forms of nitric oxide synthase in human platelets. (1995) (183)
- Dot1a-AF9 Complex Mediates Histone H3 Lys-79 Hypermethylation and Repression of ENaCα in an Aldosterone-sensitive Manner* (2006) (178)
- In situ hybridization localization of mRNA encoding inducible nitric oxide synthase in rat kidney. (1994) (171)
- Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. (2007) (153)
- Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules. (1990) (134)
- Protein-protein interactions controlling nitric oxide synthases. (2000) (132)
- Proteomic Analysis of S-Nitrosylated Proteins in Mesangial Cells * (2003) (113)
- Nitric oxide synthesis in the kidney: isoforms, biosynthesis, and functions in health. (2004) (110)
- Molecular biology of natriuretic peptides and nitric oxide synthases. (2001) (105)
- Histone deacetylases augment cytokine induction of the iNOS gene. (2002) (105)
- Influence of Na+ intake on dopamine-induced inhibition of renal cortical Na(+)-K(+)-ATPase. (1990) (101)
- Narrative Review: Evolving Concepts in Potassium Homeostasis and Hypokalemia (2009) (87)
- A novel N-terminal splice variant of the rat H+-K+-ATPase alpha2 subunit. Cloning, functional expression, and renal adaptive response to chronic hypokalemia. (1998) (86)
- Functional Expression of the Colonic H+,K+-ATPase α-Subunit (1996) (85)
- The STAT3 DNA-binding domain mediates interaction with NF-kappaB p65 and inducible nitric oxide synthase transrepression in mesangial cells. (2004) (82)
- Locally formed dopamine inhibits Na+-K+-ATPase activity in rat renal cortical tubule cells. (1988) (80)
- Chronic hypokalemia enhances expression of the H(+)-K(+)-ATPase alpha 2-subunit gene in renal medulla. (1996) (74)
- Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion. (2002) (74)
- Nitric Oxide-dependent Negative Feedback of PARP-1 trans-Activation of the Inducible Nitric-oxide Synthase Gene* (2006) (70)
- Hypothermia protects against gut ischemia/reperfusion-induced impaired intestinal transit by inducing heme oxygenase-1. (2003) (69)
- Aldosterone-sensitive repression of ENaCalpha transcription by a histone H3 lysine-79 methyltransferase. (2006) (69)
- Sirtuin 1 Functionally and Physically Interacts with Disruptor of Telomeric Silencing-1 to Regulate α-ENaC Transcription in Collecting Duct* (2009) (69)
- Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase. (2004) (65)
- Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages. (2001) (65)
- NF-κB inhibits transcription of the H+-K+-ATPase α2-subunit gene: role of histone deacetylases (2002) (65)
- Role of NF-kappa B in the regulation of inducible nitric oxide synthase in an MTAL cell line. (1995) (64)
- Differential induction of PPAR-gamma by luminal glutamine and iNOS by luminal arginine in the rodent postischemic small bowel. (2006) (63)
- α-Melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury (2002) (63)
- ISCHEMIC PRECONDITIONING PROTECTS AGAINST GUT DYSFUNCTION AND MUCOSAL INJURY AFTER ISCHEMIA/REPERFUSION INJURY (2005) (61)
- Expression and cellular localization of mRNA encoding the "gastric" isoform of H(+)-K(+)-ATPase alpha-subunit in rat kidney. (1995) (57)
- Localization and regulation of nitric oxide synthase isoforms in the kidney. (1999) (56)
- Macrophages and chronic renal allograft nephropathy. (1996) (54)
- Effects of NF-κB inhibition on mesenteric ischemia-reperfusion injury (2003) (53)
- Epigenetics and the control of epithelial sodium channel expression in collecting duct. (2009) (53)
- Silver ion (Ag+)-Induced increases in cell membrane K+ and Na+ permeability in the renal proximal tubule: Reversal by thiol reagents (1988) (52)
- Early effects of uranyl nitrate on respiration and K+ transport in rabbit proximal tubule. (1989) (50)
- Protein-protein interactions involving inducible nitric oxide synthase. (2003) (48)
- Renal H,K-ATPase: structure, function and regulation. (1996) (47)
- AF17 Competes with AF9 for Binding to Dot1a to Up-regulate Transcription of Epithelial Na+ Channel α* (2009) (47)
- Hypermethylation of the Inducible Nitric-oxide Synthase Gene Promoter Inhibits Its Transcription* (2004) (44)
- Effects of chronic hypokalemia on renal expression of the "gastric" H(+)-K(+)-ATPase alpha-subunit gene. (1996) (41)
- Ultrastructure of the thick ascending limb of Henle in the rat kidney. (1984) (40)
- NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases. (2002) (39)
- Hypertension and renal dysfunction in bone marrow transplant recipients. (1988) (37)
- Cytokines activate inducible nitric oxide synthase gene transcription in inner medullary collecting duct cells. (1995) (36)
- Insulin-Stimulated Cyclic Guanosine Monophosphate Inhibits Vascular Smooth Muscle Cell Migration by Inhibiting Ca/Calmodulin-Dependent Protein Kinase II (2003) (36)
- CCAAT/enhancer binding protein-β trans-activates murine nitric oxide synthase 2 gene in an MTAL cell line. (1999) (34)
- Assembly of Na,K-ATPase α-subunit isoforms with Na,K-ATPase β-subunit isoforms and H,K-ATPase β-subunit (1994) (34)
- Nitric oxide inhibits transcription of the Na+-K+-ATPase α1-subunit gene in an MTAL cell line. (1999) (33)
- Reflections on use of the renal biopsy as the "gold standard" in distinguishing transplant rejection from cyclosporine nephrotoxicity. (1985) (33)
- Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury. (2003) (33)
- Sch-28080 depletes intracellular ATP selectively in mIMCD-3 cells. (2000) (30)
- α-MSH inhibits induction of C/EBPβ-DNA binding activity and NOS2 gene transcription in macrophages (2000) (30)
- Differential actions of cisplatin on renal proximal tubule and inner medullary collecting duct cells. (1993) (29)
- Differential expression and cellular distribution of mRNAs encoding alpha- and beta-isoforms of Na(+)-K(+)-ATPase in rat kidney. (1993) (29)
- A 'BOLD' new approach to renal oxygen economy. (1996) (28)
- USF-1 and USF-2 trans-repress IL-1beta-induced iNOS transcription in mesangial cells. (2002) (28)
- Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide (2012) (27)
- α-MELANOCYTE STIMULATING HORMONE PROTECTS AGAINST H2O2-INDUCED INHIBITION OF WOUND RESTITUTION IN IEC-6 CELLS VIA A SYK KINASE– AND NF-κβ–DEPENDENT MECHANISM (2004) (25)
- Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells. (2006) (23)
- Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct. (2013) (22)
- Sulfhydryl-reactive heavy metals increase cell membrane K+ and Ca2+ transport in renal proximal tubule (2005) (21)
- Segmental localization of mRNAs encoding Na+-K+-ATPase α- and β-subunit isoforms in rat kidney using RT-PCR (1994) (21)
- Myelodysplastic syndrome manifesting as Sweet's Syndrome and bronchiolitis obliterative organizing pneumonia. (2006) (20)
- Alpha-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury. (2002) (19)
- Structure, promoter analysis, and chromosomal localization of the murine H(+)/K(+)-ATPase alpha 2 subunit gene. (2001) (19)
- Src Activation of NF-κB Augments IL-1β–Induced Nitric Oxide Production in Mesangial Cells (2005) (19)
- Coordinated regulation of intracellular K+ in the proximal tubule: Ba2+ blockade down-regulates the Na+,K+-ATPase and up-regulates two K+ permeability pathways. (1989) (18)
- PRETREATMENT WITH BONE MORPHOGENETIC PROTEIN-7 (BMP-7) MIMICS ISCHEMIA PRECONDITIONING FOLLOWING INTESTINAL ISCHEMIA/REPERFUSION INJURY IN THE INTESTINE AND LIVER (2008) (18)
- Expression profile of a human inducible nitric oxide synthase promoter reporter in transgenic mice during endotoxemia. (2005) (18)
- CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells. (2010) (16)
- Succinate alters respiration, membrane potential, and intracellular K+ in proximal tubule. (1988) (16)
- Modulation of osmolytes in MDCK cells by solutes, inhibitors, and vasopressin. (1990) (16)
- Intestinal Ischemic Preconditioning After Ischemia/Reperfusion Injury in Rat Intestine: Profiling Global Gene Expression Patterns (2010) (15)
- Lipopolysaccharide-Induced Changes in Rat Gastric H/K-ATPase Expression (2004) (15)
- In vivo expression profile of a H+-K+-ATPase alpha2-subunit promoter-reporter transgene. (2004) (15)
- An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene. (2013) (15)
- Early renal pathophysiology in an acute model of cyclosporine nephrotoxicity in rats. (1987) (15)
- Acute renal failure produced by combining cyclosporine and brief renal ischemia in the Munich Wistar rat. (1986) (15)
- Epigenetics and the control of the collecting duct epithelial sodium channel. (2013) (14)
- Functional expression of the colonic H+,K+-ATPase alpha-subunit. Pharmacologic properties and assembly with X+,K+-ATPase beta-subunits. (1996) (14)
- CCAAT/enhancer binding protein-beta trans-activates murine nitric oxide synthase 2 gene in an MTAL cell line. (1999) (12)
- Delayed Administration of &agr;-Melanocyte-Stimulating Hormone or Combined Therapy with Bay 11-7085 Protects Against Gut Ischemia–Reperfusion Injury (2003) (12)
- Renal blood flow, glomerular filtration rate, and renal morphology in cyclosporine-induced acute renal failure in Munich-Wistar rats. (1986) (12)
- Sp1 trans-activates the murine H(+)-K(+)-ATPase alpha(2)-subunit gene. (2004) (11)
- Molecular Regulation of Trypanosoma congolense-Induced Nitric Oxide Production in Macrophages (2013) (11)
- Src activation of NF-kappaB augments IL-1beta-induced nitric oxide production in mesangial cells. (2006) (11)
- Cellular pathways of potassium transport in renal inner medullary collecting duct. (1989) (10)
- Acute renal failure following percutaneous transhepatic cholangiography. A retrospective study. (1986) (10)
- A cell biologist's perspective on sites of Na,K-ATPase regulation. (1991) (10)
- Proteomic analysis reveals novel protein targets of S-nitrosylation in mesangial cells. (2004) (9)
- Calcium channel blockade in dialysis patients with left ventricular hypertrophy and well-preserved systolic function. (1987) (9)
- A Novel N-terminal Splice Variant of the Rat H+-K+-ATPase α2 Subunit (1998) (8)
- Segmental localization of mRNAs encoding Na(+)-K(+)-ATPase alpha- and beta-subunit isoforms in rat kidney using RT-PCR. (1994) (8)
- Relation between the anion exchange protein in kidney medullary collecting duct cells and red cell band 3 (1988) (8)
- Nitric oxide inhibits transcription of the Na+-K+-ATPase alpha1-subunit gene in an MTAL cell line. (1999) (8)
- CREB trans-activates the murine H(+)-K(+)-ATPase alpha(2)-subunit gene. (2004) (8)
- Thiazide-induced hyponatremia. (1986) (7)
- Assembly of Na,K-ATPase alpha-subunit isoforms with Na,K-ATPase beta-subunit isoforms and H,K-ATPase beta-subunit. (1994) (7)
- Sp1 trans-activates and is required for maximal aldosterone induction of the αENaC gene in collecting duct cells. (2013) (6)
- How will gene therapy apply to the kidney in the 21st century? (2000) (6)
- NO break-ins at water gate. (2006) (5)
- Structure and regulation of the mDot 1 gene , a mouse histone H 3 methyltransferase (2003) (5)
- Alpha-melanocyte stimulating hormone protects against H2O2-induced inhibition of wound restitution in IEC-6 cells via a Syk kinase- and NF-kappabeta-dependent mechanism. (2004) (5)
- MMA (2020) (4)
- S-Nitrosylation: Targets, Controls and Outcomes (2006) (4)
- Aldosterone and Epithelial Na Channels An Af 9 cis-element directly targets Dot 1 a to mediate transcriptional repression of the ENaC gene (2013) (3)
- Physical and functional interaction of Rnf2 with Af9 regulates basal and aldosterone-stimulated transcription of the α-ENaC gene in a renal collecting duct cell line (2013) (3)
- alpha-MSH inhibits induction of C/EBPbeta-DNA binding activity and NOS2 gene transcription in macrophages. (2000) (3)
- Molecular approaches to renal physiology and therapeutics. (1998) (3)
- 2009 Southern Society For Clinical Investigation presidential address: opportunity knocks. (2009) (2)
- ISCHEMIC PRECONDITIONING PROTECTS AGAINST INTESTINAL ISCHEMIA/REPERFUSION INJURY.: 179 (2004) (2)
- MMP (2020) (2)
- Renal morphology and function and urine electrolytes in experimental acute renal failure produced by cyclosporine and ischemia. (1985) (2)
- FLUID AND ELECTROLYTE HOMEOSTASIS (2009) (2)
- Transcriptional profiling of ischemic preconditioning in rat intestine following ischemia/reperfusion injury (2006) (1)
- CREB trans-activates the murine H-K-ATPase 2-subunit gene (2004) (1)
- New mechanisms for transcriptional repression of ENaC And iNOS. (2007) (1)
- in rabbit proximal tubule (1989) (1)
- Extracellular Na+ electrode for monitoring net Na+ flux in cell suspensions. (1989) (1)
- Sp 1 trans-activates and is required for maximal aldosterone induction of the ENaC gene in collecting duct cells (2013) (1)
- Pretreatment with BMP-7 mimics protective effects of ischemic preconditioning (IPC) following intestinal ischemia/reperfusion (IR) injury in the intestine and liver (2006) (0)
- Metabolic Fatty Liver Disease (2009) (0)
- Coordinated regulation ofintracellular K+intheproximal tubule: Ba2'blockade down-regulates theNa',K+-ATPase and up-regulates twoK+permeability pathways (kidney/ion transport/quinine/furosemide/K' channels) (1989) (0)
- Aquaporin-1 transports NO across cell membranes. Commentary (2006) (0)
- endotoxemiapromoter reporter in transgenic mice during Expression profile of a human inducible nitric oxide (2016) (0)
- Acute Renal Failure Following Percutaneous Transhepatic Cholangiography (2017) (0)
- Mild hyperphenylalaninemia (2020) (0)
- A different perspective on admission decisions. (2009) (0)
- Advances in genetic detection of kidney disease. (2003) (0)
- Lipopolysacchardide (LPS) induced inhibition of gastric acid secretion: Role of H/K-ATPase (2001) (0)
- THE ROLE OF THE GUT IN MULTIPLE ORGAN FAILURE (MOF) (2006) (0)
- isoforms in activated murine macrophages Specific association of nitric oxide synthase-2 with Rac (2016) (0)
- promoter-reporter transgene (2004) (0)
- Urine Formation: From Normal Physiology to Florid Kidney Failure (2006) (0)
- Aldosteroneplaysamajorroleintheregulationofsaltbalanceandthepathophysiologyofcardiovascular andrenaldiseases.Manyaldosterone-regulatedgenes—includingthatencodingtheepithelialNa + channel (ENaC),akeyarbiterofNa + transportinthekidneyandotherepithelia—havebeenidentified,butthemecha- nismsbywhichthehor (2007) (0)
- H2O2 AND TNF&agr; SYNERGISTICALLY INDUCE INOS AND COX-2 IN A PRO-INFLAMATORY MODEL (2006) (0)
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