Bruce Ernest Kemp
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Biochemist
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Biology
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Biochemistry
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Biology
Bruce Ernest Kemp's Degrees
- Bachelors Biochemistry University of California, Berkeley
- PhD Biochemistry Stanford University
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(Suggest an Edit or Addition)Bruce Ernest Kemp's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- AMPK in Health and Disease. (2009) (1554)
- A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. (1987) (1234)
- The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases* (2005) (974)
- Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. (1987) (939)
- AMP‐activated protein kinase phosphorylation of endothelial NO synthase (1999) (853)
- Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. (2010) (778)
- Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase (2006) (774)
- Parathyroid hormone-related protein purified from a human lung cancer cell line. (1987) (703)
- Phosphorylation of Thr495 Regulates Ca2+/Calmodulin-Dependent Endothelial Nitric Oxide Synthase Activity (2001) (693)
- The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase (2012) (678)
- Mammalian AMP-activated Protein Kinase Subfamily (*) (1996) (658)
- Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin (2013) (648)
- Coordinated Control of Endothelial Nitric-oxide Synthase Phosphorylation by Protein Kinase C and the cAMP-dependent Protein Kinase* (2001) (561)
- AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase (2011) (537)
- Dealing with energy demand: the AMP-activated protein kinase. (1999) (532)
- Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. (2007) (511)
- A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. (1986) (508)
- The Akt kinase signals directly to endothelial nitric oxide synthase (1999) (485)
- AMP-activated protein kinase, super metabolic regulator. (2001) (480)
- Faculty Opinions recommendation of Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. (2003) (438)
- Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. (2001) (424)
- Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle* (1997) (423)
- AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen (2003) (405)
- Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling. (2006) (396)
- AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise (2011) (390)
- AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5 (2008) (383)
- Reciprocal Phosphorylation and Regulation of Endothelial Nitric-oxide Synthase in Response to Bradykinin Stimulation* (2001) (378)
- AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation. (2000) (372)
- Parathyroid hormone-related protein of malignancy: active synthetic fragments. (1987) (362)
- Functional Domains of the α1 Catalytic Subunit of the AMP-activated Protein Kinase* (1998) (352)
- Effect of exercise intensity on skeletal muscle AMPK signaling in humans. (2003) (352)
- High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus (2009) (351)
- Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. (2003) (333)
- Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. (1994) (332)
- Hypothalamic CaMKK2 contributes to the regulation of energy balance. (2008) (330)
- A possible linkage between AMP‐activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway (2003) (328)
- AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation (2001) (317)
- β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK) (2010) (303)
- Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity. (2011) (289)
- CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK (2006) (279)
- Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells. (1981) (278)
- Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. (2001) (272)
- Cellular Distribution and Developmental Expression of AMP‐Activated Protein Kinase Isoforms in Mouse Central Nervous System (1999) (269)
- Regulation of AMP-activated Protein Kinase by Multisite Phosphorylation in Response to Agents That Elevate Cellular cAMP*> (2006) (266)
- Components of a Calmodulin-dependent Protein Kinase Cascade (1998) (259)
- Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes. (2008) (256)
- Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function. (2016) (242)
- Peptides and Protein Phosphorylation (1990) (240)
- Compensatory Phosphorylation and Protein-Protein Interactions Revealed by Loss of Function and Gain of Function Mutants of Multiple Serine Phosphorylation Sites in Endothelial Nitric-oxide Synthase* (2003) (233)
- Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism. (2002) (232)
- Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase. (2000) (232)
- Insulin activation of acetyl-CoA carboxylase accompanied by inhibition of the 5'-AMP-activated protein kinase. (1992) (226)
- Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue. (2006) (225)
- Identification of Regulatory Sites of Phosphorylation of the Bovine Endothelial Nitric-oxide Synthase at Serine 617 and Serine 635* (2002) (222)
- Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins. (1999) (219)
- Localization of Endothelial Nitric-oxide Synthase Phosphorylated on Serine 1179 and Nitric Oxide in Golgi and Plasma Membrane Defines the Existence of Two Pools of Active Enzyme* (2002) (217)
- Structural basis of autoregulation of phenylalanine hydroxylase (1999) (203)
- AMPK beta subunit targets metabolic stress sensing to glycogen. (2003) (203)
- Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics. (2005) (189)
- Structural basis for glycogen recognition by AMP-activated protein kinase. (2005) (189)
- Active site-directed protein regulation (1999) (186)
- AMPK functions as an adenylate charge-regulated protein kinase (2012) (179)
- Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. (2003) (177)
- AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging. (2015) (175)
- Insights into autoregulation from the crystal structure of twitchin kinase (1994) (175)
- High-density lipoprotein and apolipoprotein AI increase endothelial NO synthase activity by protein association and multisite phosphorylation. (2004) (174)
- Regulation of 5′-AMP-activated Protein Kinase Activity by the Noncatalytic β and γ Subunits* (1996) (171)
- A carboxyl-terminal peptide from the parathyroid hormone-related protein inhibits bone resorption by osteoclasts. (1991) (171)
- Bateman domains and adenosine derivatives form a binding contract. (2004) (170)
- Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport. (2000) (165)
- Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity* (2010) (164)
- Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site (2004) (161)
- Metformin Inhibits Gluconeogenesis by a Redox-Dependent Mechanism In Vivo (2018) (160)
- Substrate specificity of the cyclic AMP-dependent protein kinase. (1975) (160)
- Posttranslational Modifications of the 5′-AMP-activated Protein Kinase β1 Subunit* (1997) (159)
- A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111]. (1991) (155)
- Adipocyte triglyceride lipase expression in human obesity. (2007) (151)
- AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance* (2009) (150)
- Progressive increase in human skeletal muscle AMPKalpha2 activity and ACC phosphorylation during exercise. (2002) (148)
- Exercise increases nuclear AMPK α2 in human skeletal muscle (2003) (145)
- Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling. (2014) (142)
- Activation of adenosine 3',5'-monophosphate-dependent protein kinase in normal and malignant bone cells by parathyroid hormone, prostaglandin E2, and prostacyclin. (1981) (139)
- Short‐term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen (2005) (138)
- Impaired Cardiac Contractility Response to Hemodynamic Stress in S100A1-Deficient Mice (2002) (137)
- Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation. (1990) (137)
- A Mitotic Cascade of NIMA Family Kinases (2003) (135)
- Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. (1994) (134)
- Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP-dependent protein kinase. (1976) (134)
- Evidence for the role of AMPK in regulating PGC‐1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue (2014) (133)
- AMPK‐independent pathways regulate skeletal muscle fatty acid oxidation (2008) (131)
- AMP‐activated protein kinase isoenzyme family: subunit structure and chromosomal location (1997) (130)
- Non-catalytic - and -Subunit Isoforms of the 5′-AMP-activated Protein Kinase (*) (1996) (128)
- Ca2+ /S100 regulation of giant protein kinases (1996) (128)
- Prevention of albuminuria by aminoguanidine or ramipril in streptozotocin-induced diabetic rats is associated with the normalization of glomerular protein kinase C. (2000) (126)
- Isoform-specific Purification and Substrate Specificity of the 5′-AMP-activated Protein Kinase* (1996) (126)
- Associations of Inflammatory and Hemostatic Variables With the Risk of Recurrent Stroke (2005) (125)
- Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity. (1994) (124)
- Fatty acids stimulate AMP‐activated protein kinase and enhance fatty acid oxidation in L6 myotubes (2006) (124)
- Expression of the AMP‐activated protein kinase β1 and β2 subunits in skeletal muscle (1999) (123)
- Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. (2004) (122)
- Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity. (2015) (122)
- Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease (2016) (120)
- Chutes and Ladders: the search for protein kinases that act on AMPK. (2006) (118)
- Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer (2004) (118)
- Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clb kinase activity: a mechanism for CLB cluster gene activation. (2003) (118)
- The Protein-tyrosine Phosphatase TCPTP Regulates Epidermal Growth Factor Receptor-mediated and Phosphatidylinositol 3-Kinase-dependent Signaling* (1999) (117)
- Regulation of Channel Gating by AMP-activated Protein Kinase Modulates Cystic Fibrosis Transmembrane Conductance Regulator Activity in Lung Submucosal Cells* (2003) (115)
- AMP-activated Protein Kinase Impairs Endothelial Actin Cytoskeleton Assembly by Phosphorylating Vasodilator-stimulated Phosphoprotein* (2007) (114)
- Tissue-Specific Effects of Rosiglitazone and Exercise in the Treatment of Lipid-Induced Insulin Resistance (2007) (112)
- Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK (2014) (109)
- The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans. (2006) (108)
- AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice (2014) (108)
- Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. (2006) (106)
- SnRK1 from Arabidopsis thaliana is an atypical AMPK. (2015) (104)
- Examination of ‘lipotoxicity’ in skeletal muscle of high‐fat fed and ob/ob mice (2009) (103)
- Src Kinase Activates Endothelial Nitric-oxide Synthase by Phosphorylating Tyr-83* (2005) (103)
- Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging (2015) (103)
- Comparison of the anabolic effects of synthetic parathyroid hormone-related protein (PTHrP) 1-34 and PTH 1-34 on bone in rats. (1989) (103)
- High intensity interval training improves liver and adipose tissue insulin sensitivity (2015) (102)
- Selective hormonal activation of cyclic AMP-dependent protein kinase isoenzymes in normal and malignant osteoblasts. (1982) (102)
- Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans. (2006) (101)
- Phosphorylation at the Cyclin-dependent Kinases Site (Thr85) of Parathyroid Hormone-related Protein Negatively Regulates Its Nuclear Localization* (1999) (100)
- AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females. (2004) (100)
- Differential and common recognition of the catalytic sites of the cGMP-dependent and cAMP-dependent protein kinases by inhibitory peptides derived from the heat-stable inhibitor protein. (1986) (99)
- Reduced glycogen availability is associated with increased AMPKalpha2 activity, nuclear AMPKalpha2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle. (2006) (99)
- Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. (2003) (97)
- An activating mutation in the γ1 subunit of the AMP‐activated protein kinase (2001) (97)
- AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets (2003) (96)
- An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice (2016) (95)
- Human Factor H-related Protein 5 (FHR-5) (2001) (93)
- AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186–270)* (2005) (91)
- Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK). (2007) (91)
- Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle. (2004) (90)
- Multiple Ca-Calmodulin-dependent Protein Kinase Kinases from Rat Brain (1996) (86)
- Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits. (1996) (83)
- Exercise increases nuclear AMPK alpha2 in human skeletal muscle. (2003) (82)
- Catalytic subunits of the porcine and rat 5'-AMP-activated protein kinase are members of the SNF1 protein kinase family. (1995) (82)
- Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177. (2005) (82)
- Prediction of Myocardial Infarction by N-Terminal-Pro-B-Type Natriuretic Peptide, C-Reactive Protein, and Renin in Subjects With Cerebrovascular Disease (2005) (81)
- Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin. (2018) (81)
- AMP-activated protein kinase--the fat controller of the energy railroad. (2006) (80)
- Role of 5′AMP‐activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease (2002) (80)
- β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling (2004) (79)
- Structure and function of AMP‐activated protein kinase (2009) (79)
- Crystallization of a trimeric human T cell leukemia virus type 1 gp21 ectodomain fragment as a chimera with maltose‐binding protein (1998) (75)
- AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 (2018) (75)
- Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662. (2014) (75)
- Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis. (2015) (74)
- Calcitonin receptors of human osteoclastoma. (1987) (73)
- Cellular Stress Regulates the Nucleocytoplasmic Distribution of the Protein-tyrosine Phosphatase TCPTP* (2001) (73)
- Intensified exercise training does not alter AMPK signaling in human skeletal muscle. (2004) (73)
- Hepatic 5'-AMP-activated protein kinase: zonal distribution and relationship to acetyl-CoA carboxylase activity in varying nutritional states. (1994) (71)
- Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans. (2008) (71)
- Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation. (2007) (71)
- Expression of the AMP-activated protein kinase beta1 and beta2 subunits in skeletal muscle. (1999) (70)
- Platelet-Derived Growth Factor Receptor Transactivation Mediates the Trophic Effects of Angiotensin II In Vivo (2004) (69)
- Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase. (1973) (69)
- Autologous red cell agglutination assay for HIV-1 antibodies: simplified test with whole blood. (1988) (68)
- Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence (1997) (68)
- Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding (2016) (65)
- Activity ratio measurements reflect intracellular activation of adenosine 3',5'-monophosphate-dependent protein kinase in osteoblasts. (1982) (65)
- Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites (2008) (65)
- AMPK structure and regulation from three angles. (2007) (65)
- Regulation of Na+-coupled glucose carrier SGLT1 by AMP-activated protein kinase (2010) (65)
- Chronic rosiglitazone treatment restores AMPKalpha2 activity in insulin-resistant rat skeletal muscle. (2006) (64)
- Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats. (2008) (64)
- Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality. (2005) (64)
- Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity. (2009) (64)
- Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations (2004) (64)
- Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells (2018) (63)
- Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure (1995) (63)
- Rosiglitazone Treatment Enhances Acute AMP-Activated Protein Kinase–Mediated Muscle and Adipose Tissue Glucose Uptake in High-Fat–Fed Rats (2006) (63)
- AMP-Activated Protein Kinase Is Activated by the Stimulations of Gq-Coupled Receptors (2000) (63)
- AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270). (2005) (62)
- Choreography of AMPK activation (2014) (62)
- Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site. (2004) (62)
- NMR study of a 34-residue N-terminal fragment of the parathyroid-hormone-related protein secreted during humoral hypercalcemia of malignancy. (1989) (61)
- Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models (2014) (61)
- AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. (2015) (61)
- Identification of a Parathyroid Hormone in the Fish Fugu rubripes (2003) (60)
- AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis (2018) (59)
- Effect of exercise on protein kinase C activity and localization in human skeletal muscle (2004) (59)
- The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs (2017) (59)
- 5‐aminoimidazole‐4‐carboxamide ribonucleoside and AMP‐activated protein kinase inhibit signalling through NF‐κB (2010) (59)
- Protein kinase C pseudosubstrate prototope: structure-function relationships. (1990) (58)
- Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase. (2009) (58)
- Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons (2016) (57)
- Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1 (2016) (56)
- Role of basic residues in the phosphorylation of synthetic peptides by myosin light chain kinase. (1983) (55)
- Salicylate improves macrophage cholesterol homeostasis via activation of Ampk[S] (2015) (55)
- Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line. (2001) (55)
- Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release. (2015) (54)
- Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK. (2008) (54)
- NMR solution structure of human parathyroid hormone(1-34). (1993) (54)
- PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity (2014) (53)
- Germline deletion of AMP‐activated protein kinase β subunits reduces bone mass without altering osteoclast differentiation or function (2010) (53)
- The myosin-I-binding protein Acan125 binds the SH3 domain and belongs to the superfamily of leucine-rich repeat proteins. (1997) (53)
- Insulin resistance does not diminish eNOS expression, phosphorylation, or binding to HSP-90. (2004) (53)
- Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity. (2008) (52)
- Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery. (2001) (52)
- AMP-activated protein kinase kinase: detection with recombinant AMPK α1 subunit (2002) (52)
- AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation. (2018) (51)
- Ca2+/Calmodulin-dependent Protein Kinase Kinase β Is Regulated by Multisite Phosphorylation* (2011) (51)
- Peptide inhibitors of cAMP-dependent protein kinase. (1988) (51)
- In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase. (1978) (49)
- Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells. (2008) (49)
- Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase–Dependent Pathway That Is Impaired With Obesity (2009) (47)
- Mutations in the Gal83 Glycogen-Binding Domain Activate the Snf1/Gal83 Kinase Pathway by a Glycogen-Independent Mechanism (2004) (47)
- Multiple protein kinases from human lymphocytes. Identification enzymes phosphorylating exogenous histon and casein. (1975) (46)
- An activating mutation in the gamma1 subunit of the AMP-activated protein kinase. (2001) (45)
- Socs1 Deficiency Enhances Hepatic Insulin Signaling* (2005) (45)
- Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress (2014) (45)
- Prediction of Heart Failure by Amino Terminal-pro–B-Type Natriuretic Peptide and C-Reactive Protein in Subjects With Cerebrovascular Disease (2005) (44)
- Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans. (2006) (44)
- Functional Implications of the Human T-Lymphotropic Virus Type 1 Transmembrane Glycoprotein Helical Hairpin Structure (2000) (44)
- AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation (2014) (43)
- Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity (2009) (43)
- ADR1c mutations enhance the ability of ADR1 to activate transcription by a mechanism that is independent of effects on cyclic AMP-dependent protein kinase phosphorylation of Ser-230 (1992) (43)
- Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms (2020) (43)
- Solution Structure of Parathyroid Hormone Related Protein (Residues 1–34) Containing an Ala Substituted for an Ile in Position 15 (PTHrP[Ala15]-(1–34))* (1997) (43)
- Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immunoelectron Microscopy (2009) (42)
- A Mitotic Cascade of NIMA Family Kinases Nercc1/Nek9 ACTIVATES THE Nek6 AND Nek7 KINASES* (2003) (42)
- Inhibition of Kir2.1 (KCNJ2) by the AMP-activated protein kinase. (2011) (42)
- Soluble vascular cell adhesion molecule 1 and N-terminal pro-B-type natriuretic peptide in predicting ischemic stroke in patients with cerebrovascular disease. (2006) (41)
- Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity (2016) (41)
- FHA domain boundaries of the Dun1p and Rad53p cell cycle checkpoint kinases (2000) (40)
- Circular dichroic evidence for an ordered sequence of ligand/binding site interactions in the catalytic reaction of the cAMP-dependent protein kinase. (1985) (40)
- Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. (2008) (40)
- AMP-Activated protein kinase is activated by the stimulations of G(q)-coupled receptors. (2000) (39)
- The Phosphoprotein StarD10 Is Overexpressed in Breast Cancer and Cooperates with ErbB Receptors in Cellular Transformation (2004) (39)
- Differential Regulation of Adiponectin Receptor Gene Expression by Adiponectin and Leptin in Myotubes Derived from Obese and Diabetic Individuals (2006) (38)
- The Outcome of Renal Ischemia-Reperfusion Injury Is Unchanged in AMPK-β1 Deficient Mice (2012) (38)
- A synthetic peptide analog of the putative substrate‐binding motif activates protein kinase C (1989) (37)
- Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance (2018) (37)
- Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase (2011) (36)
- Human placental calcitonin receptors. (1988) (36)
- Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation. (2009) (35)
- Rapid whole blood assay for HIV-1 seropositivity using an Fab-peptide conjugate. (1991) (34)
- Synthetic peptide substrates for the membrane tyrosine protein kinase stimulated by epidermal growth factor. (1984) (32)
- Peptide Specificity Determinants at P−7 and P−6 Enhance the Catalytic Efficiency of Ca2+/Calmodulin-dependent Protein Kinase I in the Absence of Activation Loop Phosphorylation* (1999) (32)
- Down‐regulation of Na+‐coupled glutamate transporter EAAT3 and EAAT4 by AMP‐activated protein kinase (2010) (32)
- A rapid whole‐blood immunoassay system (1990) (31)
- Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK. (2014) (31)
- Evidence That the Pertussis Toxin-sensitive Trimeric GTP-binding Protein Gi2 Is Required for Agonist- and Store-activated Ca2+ Inflow in Hepatocytes (*) (1995) (31)
- Phosphorylation of Neuronal and Endothelial Nitric Oxide Synthase in the Kidney with High and Low Salt Diets (2006) (30)
- Actions of parathyroid hormone-related protein on the rat kidney in vivo. (1989) (30)
- Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney (2016) (30)
- The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2 (2020) (30)
- Histone phosphatase and cyclic nucleotide-stimulated protein kinase from human lymphocytes. (1972) (29)
- Phosphorylation of ribosomal protein S6 and a peptide analogue of S6 by a protease‐activated kinase isolated from rat liver (1984) (29)
- The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice (2015) (29)
- Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS (2005) (29)
- Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4. (2018) (29)
- Faculty Opinions recommendation of Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. (2003) (29)
- Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage. (2008) (28)
- Substrate specificity and inhibitor sensitivity of Ca2+/S100-dependent twitchin kinases. (1996) (28)
- Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice (2006) (28)
- Reduced NOS3 Phosphorylation Mediates Reduced NO/cGMP Signaling in Mesenteric Arteries of Deoxycorticosterone Acetate-Salt Hypertensive Rats (2004) (28)
- Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells (2006) (27)
- Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise. (2006) (27)
- Antibody epitopes sensitive to the state of human immunodeficiency virus type 1 gp41 oligomerization map to a putative alpha-helical region. (1992) (26)
- NMR solution structure of the [Ala26]parathyroid-hormone-related protein(1-34) expressed in humoral hypercalcemia of malignancy. (1993) (26)
- Histone 4 phosphotransferase activities in proliferating lymphocytes. Partial purification and characterization of an enzyme specific for Ser-47. (1977) (25)
- Interaction of the recombinant S100A1 protein with twitchin kinase, and comparison with other Ca2+-binding proteins. (1997) (25)
- AMPK β1 reduces tumor progression and improves survival in p53 null mice (2017) (25)
- Muscle Phosphorylase Kinase Is Not a Substrate of AMP-Activated Protein Kinase (2000) (24)
- Structure study of osteostatin PTHrP[Thr107](107-139). (1999) (24)
- Muscle‐specific AMPK β1β2‐null mice display a myopathy due to loss of capillary density in nonpostural muscles (2014) (24)
- Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder (2015) (24)
- AMPK subunit interactions; β1:γ1 association requires β1 THR-263 and TYR-267 (2007) (24)
- Dysregulation of muscle lipid metabolism in rats selectively bred for low aerobic running capacity. (2007) (24)
- AMP-activated protein kinase kinase: detection with recombinant AMPK alpha1 subunit. (2002) (23)
- Use of a conserved immunodominant epitope of HIV surface glycoprotein gp41 in the detection of early antibodies. (1990) (23)
- Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment. (2008) (23)
- Regulation of protein kinases by pseudosubstrate prototopes. (1989) (23)
- Evidence for a second phosphorylation site on eIF‐2α from rabbit reticulocytes (1987) (23)
- Arg21 is the preferred kexin cleavage site in parathyroid-hormone-related protein. (1995) (22)
- AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267. (2008) (22)
- Evidence that a low-molecular-mass GTP-binding protein is required for store-activated Ca2+ inflow in hepatocytes. (1997) (22)
- Adiponectin: starving for attention. (2007) (22)
- CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins (2020) (21)
- Recognition of envelope and tat protein synthetic peptide analogs by HIV positive sera or plasma (1988) (21)
- Constitutive c-Myb amino-terminal phosphorylation and DNA binding activity uncoupled during entry and passage through the cell cycle (2001) (21)
- Skeletal muscle basal AMP-activated protein kinase activity is chronically elevated in alloxan-diabetic dogs: impact of exercise. (2003) (20)
- Phosphorylation of a synthetic gastrin peptide by the tyrosine kinase of A431 cell membranes. (1982) (20)
- Production, secretion, and biological activity of the C-terminal flanking peptide of human progastrin. (2006) (20)
- Human immunodeficiency virus type 1 and 2 envelope glycoproteins oligomerize through conserved sequences (1997) (20)
- AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1. (2013) (20)
- Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise (2015) (19)
- Mutation-Directed Chemical Cross-Linking of Human Immunodeficiency Virus Type 1 gp41 Oligomers (1998) (19)
- Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase (1997) (19)
- The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis. (2004) (19)
- Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression (2015) (18)
- A Simple Preparation ofO-Phospho-L-tyrosine (1983) (18)
- Intrasteric regulation of protein kinases. (1997) (18)
- Synapsins as major neuronal Ca2+/S100A1-interacting proteins. (1999) (18)
- Characteristics of selective activation of cyclic AMP-dependent protein kinase isoenzymes by calcitonin and prostaglandin E2 in human breast cancer cells. (1984) (17)
- Expression and biochemical analysis of the entire HIV‐2 gp41 ectodomain: determinants of stability map to N‐ and C‐terminal sequences outside the 6‐helix bundle core (2004) (17)
- Stabilized NMR structure of the hypercalcemia of malignancy peptide PTHrP[Ala-26](1-34)amide. (1994) (17)
- Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells. (2009) (16)
- AMPK β1 activation suppresses antipsychotic‐induced hyperglycemia in mice (2019) (16)
- Biologically active, derivatizable salmon calcitonin analog: design, synthesis, and applications. (1988) (16)
- Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation (2017) (16)
- Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization. (2005) (16)
- Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism (2020) (15)
- Regulation of membrane-associated tyrosine phosphatases in UMR 106.06 osteoblast-like cells. (1995) (15)
- Reversible calcitonin binding to solubilized sheep brain binding sites. (1991) (15)
- AICAR inhibits the Na+/H+ exchanger in rat hearts—possible contribution to cardioprotection (2006) (15)
- ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways (2019) (15)
- Heterogeneous effects of exogenous IL‐2 on HIV‐specific cell‐mediated immunity (CMI) (1992) (14)
- Synthesis of protected derivatives of O-phosphotyrosine incorporation in a heptapeptide (1984) (13)
- Evidence that the PTH receptor binding site on PTHrP(1-34) can hinge at Arg19/Arg20. (1996) (13)
- Inhibition of Connexin 26 by the AMP-Activated Protein Kinase (2011) (12)
- Protein kinase CK2: biphasic kinetics with peptide substrates. (1996) (12)
- Humoral hypercalcemia of malignancy: involvement of a novel hormone. (1988) (12)
- AMPK mediates energetic stress‐induced liver GDF15 (2020) (12)
- Nonmuscle myosin phosphorylation sites for calcium-dependent and calcium-independent protein kinases. (1986) (12)
- Prevailing hyperglycemia is critical in the regulation of glucose metabolism during exercise in poorly controlled alloxan-diabetic dogs. (2005) (12)
- β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase (2016) (11)
- NMR of a synthetic peptide spanning the triphosphate binding site of adenosine 5'-triphosphate in actin. (1987) (11)
- Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha2beta2gamma1 by the Glucose Importagog SC4 (2018) (11)
- Reduced skeletal muscle AMPK and mitochondrial markers do not promote age-induced insulin resistance. (2014) (11)
- Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo. (2012) (11)
- Casein kinase II β-subunit inhibits the activity of the catalytic α-subunit in the absence of salt (1993) (11)
- Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice (2017) (11)
- Intrasteric regulation of calmodulin-dependent protein kinases. (1996) (10)
- Evolutionary Conservation of the Membrane Fusion Machine (1999) (10)
- Activation of AMPK reduces the co-transporter activity of NKCC1 (2014) (10)
- Post-Translational Modifications of the Energy Guardian AMP-Activated Protein Kinase (2021) (10)
- Synapsins as major neuronal Ca 2 + / S 100 A 1-interacting proteins (1999) (10)
- Low-density lipoprotein particles and risk of intracerebral haemorrhage in subjects with cerebrovascular disease (2007) (9)
- Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion. (2006) (9)
- Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue (American Journal of Physiology - Endocrinology and Metabolism (E500-E508)) (2009) (9)
- Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress. (2008) (9)
- Kinetics of the autologous red cell agglutination test. (1993) (9)
- Nascent peptide in the ‘ birth canal ’ of the ribosome (2006) (8)
- Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide in individuals with cerebrovascular disease (2007) (8)
- Solubilization of functional calcitonin receptors. (1988) (8)
- Human monoclonal antibodies to HIV-1: cross-reactions with gag and env products. (1989) (8)
- A Simple Preparation of O-Phospho-L-tyrosine (1983) (8)
- Myosin light chain kinase binding to plastic (1982) (8)
- Crystallization and preliminary X-ray analysis of the auto-inhibited twitchin kinase. (1994) (8)
- Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo (2018) (8)
- Breast cancer protein StarD10 identified by three‐dimensional separation using free‐flow electrophoresis, reversed‐phase high‐performance liquid chromatography, and sodium dodecyl sulfate‐polyacrylamide gel electrophoresis (2005) (7)
- The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers (2018) (7)
- ATP sensitive bi-quinoline activator of the AMP-activated protein kinase. (2014) (6)
- Functional analysis of an R311C variant of Ca2+‐calmodulin‐dependent protein kinase kinase‐2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder (2020) (6)
- A rapid test for endotoxin in whole blood. (1995) (6)
- An AMPKα2-specific phospho-switch controls lysosomal targeting for activation. (2022) (6)
- The effect of somatostatin on the activation of adenosine 3',5'-monophosphate-dependent protein kinase in isolated rat islets of Langerhans. (1980) (5)
- Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice. (2018) (5)
- Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo (2019) (5)
- Crystallization of protein kinases and phosphatases (1999) (5)
- Metabolism: Energy sensing through a sugar diphosphate (2017) (5)
- High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes (2009) (5)
- Metabolic remodelling in adipocytes promotes CNTF-mediated fat loss in obesity (2008) (5)
- N-terminal residues 105-117 of HIV-1 gp120 are not involved in CD4 binding. (1991) (5)
- FTIR spectroscopy study of PTHrP(1-34) involved in humoral hypercalcaemia of malignancy. (1993) (4)
- Synthetic peptides representing sequences within gp41 of HIV as immunogens for murine T- and B-cell responses (2005) (4)
- Structure of the pseudosubstrate recognition site of chicken smooth muscle myosin light chain kinase. (1996) (4)
- Effects of hemin on rat liver cyclic AMP-dependent protein kinases in cell extracts and intact hepatocytes. (1985) (4)
- Simplified conjugation chemistry for coupling peptides to F(ab') fragments: autologous red cell agglutination assay for HIV-1 antibodies. (1994) (4)
- Autologous red cell agglutination test for antibodies to feline immunodeficiency virus. (1994) (4)
- Effects of PKB/AKT inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue. (2020) (4)
- Salsalate reduces atherosclerosis through AMPKβ1 in mice (2021) (4)
- Mice with Whole-Body Disruption of AMPK-Glycogen Binding Have Increased Adiposity, Reduced Fat Oxidation and Altered Tissue Glycogen Dynamics (2021) (4)
- Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis (2022) (3)
- Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism (2022) (3)
- CALMODULIN-DEPENDENT PROTEIN KINASE KINASE IS REGULATED BY MULTI-SITE PHOSPHORYLATION (2011) (3)
- MOLECULAR CLONING, FUNCTIONAL CHARACTERIZATION AND CELLULAR LOCALIZATION OF Ca 21 /CALMODULIN-DEPENDENT PROTEIN KINASE KINASE b* (1998) (3)
- Principles of Kinase Regulation (2010) (3)
- Voluntary physical activity protects against olanzapine-induced hyperglycemia. (2020) (3)
- Chicken smooth muscle myosin light chain kinase is acetylated on its NH2-terminal methionine (1993) (2)
- Cellular Bioenergetics and AMPK and TORC1 Signalling in Blood Lymphoblasts Are Biomarkers of Clinical Status in FMR1 Premutation Carriers (2021) (2)
- AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue. (2021) (2)
- Comparison of the effects of amino-terminal synthetic parathyroid hormone-related peptide (PTHrP) of malignancy and parathyroid hormone on resorption of cultured fetal rat long bones (1990) (2)
- High Density Lipoprotein Modulates Glucose Metabolism by Multiple Mechanisms (2009) (2)
- AMPK b 1 reduces tumor progression and improves survival in p 53 null mice (2017) (2)
- Mice lacking AMP-activated kinase (AMPK) subunits β1 or β2 have low bone mass, while AICAR acts AMPK-independently to increase osteoclast formation (2009) (2)
- Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator (2022) (2)
- Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis (2020) (2)
- Identification of Functional Domains of the Inhibitor Protein of Camp-Dependent Protein Kinase (1987) (2)
- Small Cell Lung Cancer Cells − LKB 1-Mutant Non Dependent Death in − AMP-Activated Protein Kinase Phosphatidylinositol Ether Lipid Analogues Induce (2008) (2)
- Protein kinase activity in commercially available crystalline yeast alcohol dehydrogenase. (1973) (2)
- Insert regions in domain X of the casein kinase II catalytic subunit. (1995) (2)
- CD8+ T-cells from HIV-infected patients can either augment or abrogate HIV-specific lymphoproliferation. (1992) (2)
- Fake Inhibitors: AMPK Activation Trumps Inhibition. (2017) (2)
- Reduced NOS 3 Phosphorylation Mediates Reduced NO / cGMP Signaling in Mesenteric Arteries of Deoxycorticosterone Acetate-Salt Hypertensive Rats (2004) (2)
- Meteorin-like (Metrnl) adipomyokine improves glucose tolerance in type 2 diabetes via AMPK pathway (2018) (2)
- AMP-activated Protein Kinase Subunit Interactions (2008) (2)
- Evidence for a second phosphorylation site on eIF-2 alpha from rabbit reticulocytes. (1987) (2)
- Characterization of sheepbrain calcitonin receptors (1990) (1)
- Novel binding site for allosteric activation of AMPK (2016) (1)
- CHAPTER 89 – Principles of Kinase Regulation (2003) (1)
- Hawley Kinase The Ancient Drug Salicylate Directly Activates AMP-Activated Protein (2012) (1)
- Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene (2021) (1)
- Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer. (2018) (1)
- Protein Serine/Threonine Kinases (2000) (1)
- Amino-terminal pro-B-type natriuretic peptide (NT-proBNP): a risk factor for most seasons (2005) (1)
- The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs (2017) (1)
- Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide levels in subjects with cerebrovascular disease (2006) (1)
- Disrupting AMPK-Glycogen Binding in Mice Increases Carbohydrate Utilization and Reduces Exercise Capacity (2022) (1)
- the glycogen-binding domain of the AMP-activated protein kinase (2005) (1)
- Abstract 20618: Phosphorylation of Acetyl-coa Carboxylase by Ampk In Platelets Controls Thromboxane Generation, Dense Granules Secretion and Thrombus Formation (2017) (1)
- Absence of the β1 subunit of AMP‐activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes (2019) (1)
- Correction: Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models (2014) (1)
- AMPK regulates GLUT4 expression via histone deacetylase 5 (2006) (1)
- Erratum to: Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity (2009) (1)
- Bone resorption inhibiting compounds and compositions (1991) (1)
- Categorising features of geological terranes with geodiversity metrics: Enhancing exploration of multiple geological models (2011) (1)
- Synthesis of O‐phosphonotyrosyl peptides (2009) (1)
- Substrates of Cyclic Nucleotide-Dependent Protein Kinases (2010) (1)
- Peptide substrates of cyclic nucleotide-dependent protein kinases (2004) (1)
- Faculty Opinions recommendation of Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity. (2005) (0)
- Secretion, production and biological activity of the human C-terminal flanking peptide of progastrin (2006) (0)
- X-ray crystal structure of AMP-activated protein kinase alpha-2/alpha-1 RIM chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) beta-1 gamma-1) co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid) (2016) (0)
- Inhibition of AMPK-HMGCR signaling promotes the development of atherosclerosis and hepatic steatosis (2019) (0)
- Abstract 533: Salicylate Restores Macrophage Cholesterol Homeostasis via Activation of AMP-Activated Protein Kinase (2015) (0)
- Compound and compositions of inhibition of bone resorption. (1991) (0)
- Faculty Opinions recommendation of AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress. (2006) (0)
- Active protein for liquid hypercalcemia in malignant pthrp (1995) (0)
- Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis. (2022) (0)
- The lectin-like domain of thrombomodulin and Grp78 complex exhibits novel anti-thrombotic properties. (2009) (0)
- Table of Contents (1996) (0)
- SmMLCK: Smooth muscle myosin light chain kinase (vertebrates) (1995) (0)
- P6066AMPK-ACC signaling modulates platelet phospholipids content and potentiate platelet function and thrombus formation (2018) (0)
- Investigation into the use of Tranilast for the treatment of acute myeloid leukemia (2007) (0)
- HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA (1999) (0)
- F1000Prime recommendation of Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase. (2007) (0)
- AMPK activation in the treatment of liver disease (2018) (0)
- Title : AMPK-ACC signaling modulates platelet phospholipids content and potentiates platelet function and thrombus formation Short title : AMPK-ACC signaling influences thrombus formation (2018) (0)
- AMP-activated protein kinase: dealing with energy demand (1999) (0)
- Faculty Opinions recommendation of Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. (2004) (0)
- Active tyrosine phosphatase in immunoprecipitates of multiple isoforms of Ly-5. (1990) (0)
- and protein in human skeletal muscle mRNA α Rapid exercise-induced changes in PGC-1 (2015) (0)
- GLYCOGEN REGULATED AMP-ACTIVATED PROTEIN KINASE ACTIVITY AND ACETYLCOA CARBOXYLASE PHOSPHORYLATION DURING EXERCISE (2002) (0)
- Protein phosphorylation: In-charge and networking! (1998) (0)
- Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells (2018) (0)
- Pseudosubstrate flexibility in chicken smooth muscle myosin light chain kinase. (1996) (0)
- controlled alloxan-diabetic dogs glucose metabolism during exercise in poorly Prevailing hyperglycemia is critical in the regulation of (2015) (0)
- controlled alloxan-diabetic dogs glucose metabolism during exercise in poorly Prevailing hyperglycemia is critical in the regulation of (2015) (0)
- Structure of full length human AMPK (a2b2g1) in complex with a small molecule activator SC4. (2018) (0)
- Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo (2019) (0)
- STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE (1999) (0)
- P5375A default in acetyl-CoA carboxylase phosphorylation increases thrombus growth in vitro and in vivo, and in a collagen-dependent manner (2017) (0)
- Mitochondrial fi ssion protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells (2018) (0)
- Red cell agglutination assay (1988) (0)
- 1256-P: Insights into Acetyl-Coa-Carboxylase (ACC1) Phospho-Regulation in Pancreatic Beta Cells (2021) (0)
- Architecture and intrasteric regulation of giant protein kinases (1996) (0)
- Basic and clinical science posters: Basic science of diabetes complications (2019) (0)
- Interleukin-6 increases glucose uptake but does not increase AMPK activity in L6 myotubes and perfused rat hindlimb (2004) (0)
- Can NT-proBNP monitoring help prevent cardiovascular disease? Recent Advances in Cardiovascular Disease (2007) (0)
- Meeting on AMP-activated (2003) (0)
- Faculty Opinions recommendation of AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. (2009) (0)
- Changes in the specific activity of (gamma-32P)ATP during protein kinase assays of crude lymphocyte extracts. (1974) (0)
- TWITCHIN KINASE FRAGMENT (APLYSIA), AUTOREGULATED PROTEIN KINASE DOMAIN (1997) (0)
- RENIN SECRETION IS AUGMENTED IN ACETYLCOA CARBOXYLASE KNOCKIN MICE IN RESPONSE TO A SALT DEFICIENT DIET (2010) (0)
- Casein kinase II beta-subunit inhibits the activity of the catalytic alpha-subunit in the absence of salt. (1993) (0)
- Calcium/calmodulin dependent protein kinase 2 (CaMKK2) mutation - a novel genetic cause of congenital hyperinsulinism (2017) (0)
- Parathyroid Hormone-Related Protein of Cancer: A Novel Gene Product with a PTH Protope (1989) (0)
- Regulation of no synthesis by AMP-activated protein kinase (2001) (0)
- TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS (1997) (0)
- the glycogen-binding domain of the AMP-activated protein kinase beta1 subunit (2005) (0)
- F1000Prime recommendation of Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species. (2004) (0)
- Faculty Opinions recommendation of Optimization of energy-consuming pathways towards rapid growth in HPV-transformed cells. (2007) (0)
- Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue. (2020) (0)
- Structure of full-length human AMPK (a2b1g1) in complex with a small molecule activator SC4 (2018) (0)
- SYNTHESIS OF PROTECTED DERIVATIVES OF O-PHOSPHOTYROSINE. INCORPORATION IN A HEPTAPEPTIDE (1984) (0)
- Faculty Opinions recommendation of Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. (2007) (0)
- The 78 kda glucose response protein (GRP78) is recruited to the surface of endothelium by interacting with thrombomodulin and it demonstrates antithrombotic activity. (2011) (0)
- Disruption of AMPK-glycogen binding in vivo reveals novel roles in whole-body and tissue metabolism (2019) (0)
- Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin. (2022) (0)
- Faculty Opinions recommendation of Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. (2008) (0)
- Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry (2021) (0)
- STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED (1999) (0)
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What Schools Are Affiliated With Bruce Ernest Kemp?
Bruce Ernest Kemp is affiliated with the following schools: