Bruce Ganem

Bruce Ganem's AcademicInfluence.com Rankings

Bruce Ganem

Chemistry

#1776

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#2569

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Chemistry

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Bruce Ganem's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

RNA world (1987) (2682)
Strategies for innovation in multicomponent reaction design. (2009) (904)
Detection of noncovalent receptor-ligand complexes by mass spectrometry (1991) (438)
New methods for the oxidation of aldehydes to carboxylic acids and esters (1968) (427)
Observation of noncovalent enzyme-substrate and enzyme-product complexes by ion-spray mass spectrometry (1991) (291)
Identification of two functionally different classes of exocellulases. (1996) (290)
INHIBITORS OF CARBOHYDRATE-PROCESSING ENZYMES : DESIGN AND SYNTHESIS OF SUGAR-SHAPED HETEROCYCLES (1996) (200)
Synthetically useful reactions with metal boride and aluminide catalysts (1986) (197)
Mechanism and synthetic utility of boron trifluoride etherate promoted organolithium additions (1984) (176)
ATOMIC-STRUCTURE OF THE BURIED CATALYTIC POCKET OF ESCHERICHIA-COLI CHORISMATE MUTASE. (1995) (175)
Ferric chloride in acetic anhydide. Mild and versatile reagent for the cleavage of ethers (1974) (146)
From glucose to aromatics: recent developments in natural products of the shikimic acid pathway (1978) (141)
Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. (1995) (141)
Lithium and potassium trialkylborohydrides. Reagents for direct reduction of .alpha.,.beta.-unsaturated carbonyl compounds to synthetically versatile enolate anions (1976) (136)
An exceptionally mild deprotection of phthalimides (1984) (135)
The mechanism of rearrangement of chorismic acid and related compounds (1987) (122)
.alpha.-Silylated vinyl ketones. New class of reagents for the annelation of ketones (1973) (119)
Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry (1995) (111)
Mechanism of sodium borohydride-cobaltous chloride reductions (1982) (110)
Detection of oligonucleotide duplex forms by ion-spray mass spectrometry (1993) (107)
Studies on the mechanism of transition-metal-assisted sodium borohydride and lithium aluminum hydride reductions (1986) (101)
Studies on heme binding in myoglobin, hemoglobin, and cytochrome c by ion spray mass spectrometry (1993) (96)
Efficient preparation of enantiomerically pure cyclic aminoalditols, total synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycyn (1985) (95)
Asymmetric total synthesis of (-)-alpha-kainic acid using an enantioselective, metal-promoted ene cyclization. (2001) (91)
New insight into the catalytic mechanism of chorismate mutases from structural studies. (1995) (89)
Amidine, amidrazone, and amidoxime derivatives of monosaccharide aldonolactams: synthesis and evaluation as glycosidase inhibitors (1993) (85)
Studies on the Biginelli reaction: a mild and selective route to 3,4-dihydropyrimidin-2(1H)-ones via enamine intermediates (2006) (84)
Mass spectrometric studies on noncovalent dimers of leucine zipper peptides (1993) (84)
A new approach to porphobilinogen and its analogs (1997) (82)
Potent, broad-spectrum inhibition of glycosidases by an amidine derivative of D-glucose (1990) (79)
Characterization of benzodiazepine "combinatorial" chemical libraries by on-line immunoaffinity extraction, coupled column HPLC-ion spray mass spectrometry-tandem mass spectrometry. (1996) (79)
The Mechanism of the Claisen Rearrangement: Déjà Vu All Over Again (1996) (78)
Rapid and efficient reduction of aliphatic nitro compounds to amines (1985) (78)
Mimicking the glucosidase transition state : shape/charge considerations (1991) (77)
New chemistry of naturally occurring polyamines (1982) (76)
Chorismate Mutase-Prephenate Dehydratase from Escherichia coli (1998) (74)
Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion. (1992) (74)
Catalyzed insertion reactions of substituted α-diazoesters. A new synthesis of cis-enoates (1981) (73)
Total syntheses of (+)-castanospermine and (+)-deoxynojirimycin (1984) (72)
Effectiveness of natural and synthetic complexes of porin and O polysaccharide as vaccines against Brucella abortus in mice (1988) (71)
Synthesis of (+)-1,5-dideoxy-1,5-imino-d-galactitol, a potent α-d-galactosidase inhibitor (1987) (68)
Reduction of Secondary Carboxamides to Imines. (1996) (67)
Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. (1995) (66)
Spiroannelation of enol ethers of cyclic 1,3-diketones. Simple stereospecific synthesis of .beta.-vetivone (1973) (64)
Synthetic Studies on Mannostatin A and Its Derivatives: A New Family of Glycoprotein Processing Inhibitors (1994) (63)
Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. (2010) (63)
A new protecting group for amines. Synthesis of anticapsin from L-tyrosine (1981) (63)
Metal-promoted variants of the Passerini reaction leading to functionalized heterocycles. (2002) (57)
A new family of five-carbon iminoalditols which are potent glycosidase inhibitors (1990) (56)
A new .beta.-lactam synthesis (1982) (54)
Kinetic monitoring of enzymatic reactions in real time by quantitative high-performance liquid chromatography-mass spectrometry. (1995) (53)
Chelate selectivity in chelation-controlled allylations. A new synthesis of castanospermine and other bioactive indolizidine alkaloids (1987) (52)
Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors. (1996) (51)
A new synthesis of amides and macrocyclic lactams (1978) (51)
Analysis of the Energetics of Gas-Phase Immunophilin-Ligand Complexes by Ion Spray Mass Spectrometry (1994) (51)
Chemistry of naturally occurring polyamines. 11. Unsaturated spermidine and spermine derivatives (1987) (50)
Paclitaxel from primary taxanes: a perspective on creative invention in organozirconium chemistry. (2007) (50)
Reductive deoxygenation by Cp2ZrHCl: Selective formation of imines via zirconation/hydrozirconation of amides (1993) (49)
Chemistry of naturally occurring polyamines. VIII: Total synthesis of (+)-hypusine (1983) (49)
Studies of non-covalent interactions of actinomycin D with single-stranded oligodeoxynucleotides by ion spray mass spectrometry and tandem mass spectrometry. (1994) (48)
Regulation of phenylalanine biosynthesis. Studies on the mechanism of phenylalanine binding and feedback inhibition in the Escherichia coli P-protein. (1999) (48)
Pseudoceratidine, a marine natural product with antifouling activity: Synthetic and biological studies (1998) (48)
An improved synthesis of D-perosamine and some derivatives. (1988) (48)
Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents. (2001) (46)
Ready oxidation of halides to aldehydes using trimethylamine N-oxide in dimethylsulfoxide (1990) (46)
BF3-etherate promoted alkylation of aziridines with organocopper reagents: a new synthesis of amines (1985) (45)
Epoxides as alkene protecting groups. A mild and efficient deoxygenation (1984) (45)
Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate. (2001) (45)
Improved Oxidation of Amines with Dibenzoyl Peroxide (1983) (43)
A new oxidation of aldehydes to carboxylic acids (1980) (43)
Total synthesis of (.+-.)-4-amino-4-deoxychorismic acid: a key intermediate in the biosynthesis of p-aminobenzoic acid and L-p-aminophenylalanine (1985) (42)
Total synthesis of (−)-vertinolide. A general approach to chiral tetronic acids and butenolides from allylic alcohols (1983) (42)
Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts. (2003) (42)
A potent new class of active-site-directed glycosidase inactivators (1988) (42)
Probing the catalytic mechanism of prephenate dehydratase by site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain. (2000) (41)
STRUCTURE AND TOTAL SYNTHESIS OF HF-7, A NEUROACTIVE GLYCONUCLEOSIDE DISULFATE FROM THE FUNNEL-WEB SPIDER HOLOLENA CURTA (1999) (39)
Trifluoroacetic anhydride-catalyzed oxidation of isonitriles by DMSO: a rapid, convenient synthesis of isocyanates. (2011) (39)
Silver-assisted dimethylsulfoxide oxidations; An improved synthesis of aldehydes and ketones (1974) (38)
Conjugate reduction and reductive alkylation of .alpha.,.beta.-unsaturated cyclohexenones using potassium tri-sec-butylborohydride (1975) (37)
Enantioselective synthesis of mannostatin A: a new glycoprotein processing inhibitor (1991) (37)
Advances in the chemistry of 2,3-epoxyalcohols. New methodology for contra-trans-diaxial opening and selective enediol oxidation (1985) (36)
2-Hydroperoxyhexafluoro-2-propanol. A low-cost, catalytic oxidant for synthesis and a structural analog of naturally occurring flavin hydroperoxides (1979) (36)
Biological spin labels as organic reagents. Oxidation of alcohols to carbonyl compounds using nitroxyls (1975) (36)
A general synthesis of 2-substituted-5-aminooxazoles: building blocks for multifunctional heterocycles (2003) (35)
Going gently into flight: analyzing noncovalent interactions by mass spectrometry. (2003) (35)
Shikimate-derived metabolites. 11. A total synthesis of (.+-.)-chorismic acid (1982) (34)
syn-Stereoselective Epoxidation of Allylic Ethers Using CF3CO3H. (1986) (34)
Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor. (2000) (34)
A new synthesis of the glyoxalase-I inhibitor COTC (2000) (33)
An efficient synthesis of substituted prolines by the selective reduction and reductive cyanation of 2-pyrrolidones (2002) (33)
Total synthesis of kukoamine A, an antihypertensive constituent of lycium chinense (1981) (32)
Chemistry of naturally occurring polyamines. 10. Nonmetabolizable derivatives of spermine and spermidine (1986) (31)
Three-Component Condensation Leading to β-Amino Acid Diamides: Convergent Assembly of β-Peptide Analogues (2004) (30)
The chemistry of naturally occurring polyamines. 1. Total synthesis of celacinnine, celabenzine and maytenine (1980) (30)
A general, highly stereoselective synthesis of amines (1982) (30)
Mapping of chorismate mutase and prephenate dehydrogenase domains in the Escherichia coli T-protein. (2003) (29)
The chemistry of naturally occurring polyamines. A total synthesis of thermospermine (1980) (29)
A genetically engineered monofunctional chorismate mutase (1990) (29)
Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein. (1996) (28)
U-3'-BCIP: a chromogenic substrate for the detection of RNase A in recombinant DNA expression systems (1991) (28)
Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase (1994) (28)
Virginiamycin M: absolute configuration and synthetic studes (1982) (28)
Synthesis of 2S-carboxy-3R, 4R, 5S-trihydroxypiperidine, a naturally occurring inhibitor of β-D-glucuronidase (1985) (28)
Studies of non-metabolizable polyamines that support growth of SV-3T3 cells depleted of natural polyamines by exposure to alpha-difluoromethylornithine. (1988) (28)
Effect of 1-epoxyalkyl-1-deoxynojirimycins on exoglucosidases (1991) (27)
Evidence for covalent bonding of native hapten–protein complexes to smooth lipopolysaccharide of Brucella abortus (1984) (27)
A new approach to substituted arene oxides. Total synthesis of senepoxide and seneol (1978) (27)
ENANTIOSELECTIVE APPROACHES TO AMINOCYCLOPENTITOLS : A TOTAL SYNTHESIS OF (+)-6-EPITREHAZOLIN AND A FORMAL TOTAL SYNTHESIS OF (+)-TREHAZOLIN (1998) (27)
D-mannonolactam amidrazone. A new mannosidase inhibitor that also inhibits the endoplasmic reticulum or cytoplasmic alpha-mannosidase. (1992) (27)
A new class of endoglycosidase inhibitors: studies on endocellulases (1989) (25)
Selective benzylation of alcohols and amines under mild conditions (1989) (24)
Amidrazone analogues of D-ribofuranose as transition-state inhibitors of nucleoside hydrolase. (1994) (24)
Phosphonate analogs of chorismic acid: synthesis and evaluation as mechanism-based inactivators of chorismate mutase (1992) (24)
Total synthesis of (±)-allosamizoline from a symmetric trisubstituted cyclopentene (1994) (24)
Glutathionyl transferase catalyzed addition of glutathione to COMC: a new hypothesis for antitumor activity. (2002) (23)
A simple solution to the oxazole problem in virginiamycin M (1984) (23)
Multiple component Fischer indole reactions (2005) (23)
Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues. (2002) (22)
Shikimate-derived metabolites. 13. A key intermediate in the biosynthesis of anthranilate from chorismate (1984) (22)
One-pot synthesis of polysubstituted indoles from aliphatic nitro compounds under mild conditions. (2007) (22)
Conjugate addition of 1 - trialkylsilylpropynylcopper derivatives; a new synthesis of 1, 5-allenic and acetylenic olefins (1974) (22)
Synthesis of 1,4,6-Trideoxy-1,4-imino-D-mannitol: a potent α-mannosidase inhibitor (1985) (21)
General synthesis of pentacyclic quassinoids (1984) (21)
Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase. (2006) (21)
ON THE MECHANISM OF CHORISMATE MUTASES : CLUES FROM WILD-TYPE E. COLI ENZYME AND A SITE-DIRECTED MUTANT RELATED TO YEAST CHORISMATE MUTASE (1996) (21)
Mass Spectrometric Investigations of Drug‐Receptor Interactions (1993) (21)
Bioactive 2-oxazolines: a new approach via one-pot, four-component reaction. (2007) (20)
Shikimate-derived metabolites. 3. Total synthesis of senepoxide and seneol according to a biogenetic proposal (1978) (20)
Tandem multicomponent/click reactions : synthesis of functionalized oxazoles and tetrazoles from acyl cyanides (2007) (20)
Synthesis of glycolipid analogues that disrupt binding of HIV-1 gp120 to galactosylceramide. (2000) (20)
The structure of ferrudiol. A highly oxidized constituent of uvaria ferruginea (1982) (19)
Studies on the chemistry and reactivity of alpha-substituted ketones in isonitrile-based multicomponent reactions. (2008) (19)
Shikimate-derived metabolites. 12. Stereocontrolled total synthesis of shikimic acid and 6.beta.-deuterioshikimate (1982) (19)
Detection of noncovalent FKBP-FK506 and FKBP-Rapamycin complexes by capillary electrophoresis-mass spectrometry and capillary electrophoresis-tandem mass spectrometry (1995) (19)
GUANIDINE ANALOGS OF A DEOXYSUGAR (1995) (18)
Arene oxides in biosynthesis. On the origin of crotepoxide, senepoxide, and pipoxide (1977) (18)
Chemistry of naturally occurring polyamines. 7. Selective functionalization of hydroxyputrescine (1983) (18)
Synthesis of ceratinamine and moloka'iamine: Antifouling agents from the marine sponge Pseudoceratina purpurea (1998) (18)
Inhibition of plant glycosidases by a D-galacturonic acid analog (1990) (18)
Synthesis of cytotoxic spermidine metabolites from the soft coral (1980) (18)
Studies on the synthesis of substituted phenanthrenoids (1980) (17)
New four-component condensations leading to 2,4,5-trisubstituted oxazoles☆ (2003) (17)
Shikimate-derived metabolites. 2. Synthesis of a bacterial natural product illustrating a concerted syn-SN2' reaction (1978) (17)
Reductive deoxygenation using hydridozirconium enolates: A new synthesis of α,β-unsaturated esters (1992) (17)
(3R,4R,5S)-5-acetamido-3,4-piperidinediol: a selective hexosaminidase inhibitor. (1987) (17)
Studies on highly oxidized cyclohexanes. Structure and absolute configuration assignments. (1982) (17)
Trypanosomal nucleoside hydrolase. Resonance Raman spectroscopy of a transition-state inhibitor complex. (1996) (17)
Alkyl and cyclopropyl sugars: approaches to branched-chain D-glucofuranose derivatives☆ (1979) (17)
A practical and inexpensive ‘convertible’ isonitrile for use in multicomponent reactions (2011) (16)
Transition-state analogue inhibitors of chorismate mutase (1990) (16)
Synthesis of the antifouling polyamine pseudoceratidine and its analogs: Factors influencing biocidal activity (1996) (16)
A pharmacokinetic-pharmacodynamic modelling of the antihistaminic (H1) effects of cetirizine. (1999) (16)
Shikimate-derived metabolites. 14.1 chiral synthesis of 5-enolpyruvyl-shikimate-3-phosphate (1985) (15)
S-(-)-dinitrobiphenic acid: A selective inhibitor of Escherichia coli chorismate mutase based on prephenate mimicry (1999) (15)
Alkylation of beta-(Hydroxymethyl)pyrroles: A New Synthesis of Porphobilinogen and Other Trisubstituted Pyrroles for Photodynamic Therapy. (1996) (15)
Analysis of the Stoichiometry of the T4 Gene 45 Protein by Ion Spray Mass Spectrometry (1994) (15)
New syntheses of alkenes and alkynes from amines (1990) (15)
Amidrazone and Amidoxime Inhibitors of Squalene Hopene Cyclase. (1999) (15)
A new synthesis of caged GABA compounds for studying GABAA receptors. (2009) (15)
An Enantioselective Synthesis of (-)-Allosamidin by Asymmetric Desymmetrization of a Highly Functionalized meso-Epoxide. (1999) (15)
TOTAL SYNTHESIS OF (-)-VERTINOLIDE. A GENERAL APPROACH TO CHIRAL TETRONIC ACIDS AND BUTENOLIDES FROM ALLYLIC ALCOHOLS (1984) (14)
An improved procedure for the conversion of amines to alcohols at low temperature (1989) (14)
Differentiation of diols; A new synthesis of bromoformates and protected hydroxyaldehydes (1974) (14)
Short chemical synthesis of (-)-chorismic acid from (-)-shikimic acid (1990) (14)
Chemistry of naturally occurring polyamines. 9. Synthesis of spermidine and spermine photoaffinity labeling reagents (1985) (14)
An approach to the synthesis of lycorine (1971) (13)
Shikimate-derived metabolites. 10. Synthetic studies on the biosynthesis of para-aminobenzoic acid. (1982) (13)
Shikimate-derived metabolites revised structure and total synthesis of pipoxide (1979) (13)
New chemistry of amines. 2. A convenient synthesis of phosphotriesters from phosphoramidates (1990) (13)
A novel inhibitor of human α-L-fucosidase: Enantioselective synthesis of L-fucoamidrazone (1994) (13)
A biomimetic heteroatom oxidation (1980) (13)
Conformational and stereochemical control of an unprecedented neighboring group participation. A new, stereospecific chloroepoxide synthesis (1976) (13)
Unique methodology for the conjugate reduction and reductive alkylation of .alpha.,.beta.-unsaturated carboxylic esters (1975) (13)
Reversing the action of noncompetitive inhibitors (MK-801 and cocaine) on a protein (nicotinic acetylcholine receptor)-mediated reaction. (2003) (12)
Synthesis of (-)-3-homoshikimic acid and (-)-3-homoshikimate-3-phosphate (1993) (12)
Masked arenes; synthesis of substituted benzenes and benzene oxides (1976) (12)
Stereoselective synthetic approaches to highly substituted cyclopentanes via electrophilic additions to mono-, di-, and trisubstituted cyclopentenes. (2000) (12)
An improved synthesis of methyl 2,3-anhydro-α-d-lyxofuranoside (1983) (12)
Molecular basis of the antitumor activities of 2-crotonyloxymethyl-2-cycloalkenones. (2003) (11)
The chemistry of naturally occurring polyamines. 6. Efficient syntheses of N1- and N8-acetylspermidine (1983) (11)
Stereospecific synthesis of dl-isoepoxydon, a new metabolite of importance to the patulin pathway (1980) (11)
Role of unsaturated derivatives of spermidine as substrates for spermine synthase and in supporting growth of SV-3T3 cells. (1991) (11)
Probing the overlap of chorismate mutase and prephenate dehydrogenase sites in the escherichia coli T-protein: a dehydrogenase-selective inhibitor. (2002) (11)
Total synthesis of gentiocrucine, an unusual alkaloid containing a stable primary enamide (1976) (11)
Improved methods for the side-chain degradation of lanosterol. The synthesis of 4,4,14alpha-trimethyl-5alpha-pregn-8-en-20-one derivatives. (1974) (10)
3R,4R,Dihydroxy-L-proline: a potent and specific β-D-glucuronidase inhibitor (1985) (10)
Stereoselective fragmentation of a tricyclic diester leading to a potent chorismate mutase transition state inhibitor (1987) (10)
A new approach to four- and five-component Ugi condensations starting from nitriles (2006) (10)
CATALYTIC EPOXIDATION OF ALKENES WITH HEXAFLUOROACETONE/HYDROGEN PEROXIDE: 4,4-DIMETHYL-3,5,8-TRIOXABICYCLO(5.1.0)OCTANE (1980) (10)
Easy assembly of ligands for glycosidase affinity chromatography. (1990) (10)
Synthesis of 1-β-amino-1-deoxynojirimycins: a new family of glucosidase inhibitors (1991) (10)
Ansa macrolide synthesis II a convergent approach to maytansine (1977) (9)
A theoretical study of the chorismate synthase reaction. (2001) (9)
A Short Homochiral Synthesis of Substituted Pyrrolidines (1990) (9)
Shikimate-derived metabolites. Total synthesis of nor-chorismic acid (1978) (9)
Selenium in synthesis. Conjugated vinylic ethers, esters, and halides from .alpha.-hetero-substituted selenides (1978) (9)
Total synthesis of mololipids: a new series of anti-HIV Moloka'iamine derivatives. (2000) (8)
Design and synthesis of substrate analogs for the inhibition of dehydroquinate synthase (1989) (8)
New chemistry of diazoesters from thermal rearrangement of n-alkyl-n-nitrosoamides (1990) (8)
Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry. (2014) (8)
Alkylation of nucleic acids by the antitumor agent COMC. (2002) (8)
On the structure of naturally-occurring (+)-methyl 3,4-anhydroshikimate (1989) (8)
Synthesis of a COMC–estradiol conjugate for targeted, tissue-selective cancer chemotherapy (2009) (8)
syn-Selective additions to Garner aldehyde: synthesis of a potent glucosylceramide synthase inhibitor (2002) (7)
Is There Another Common Intermediate beyond Chorismic Acid in the Shikimate Pathway? Synthesis of trans-3-[(1-carboxyvinyl)oxy]-6-hydroxycyclohexa-1,4-diene-1-carboxylic Acid (1994) (7)
A three-component Fischer indole synthesis (2008) (7)
Selective inhibition of MCF-7(piGST) breast tumors using glutathione transferase-derived 2-methylene-cycloalkenones. (2005) (7)
The photochemistry of pyrylium salts: new photohydrations and photoamidations of heterocycles leading to bicyclic oxazolines and functionalized cyclopentenes. (2001) (7)
A comment on the reactivity of methoxymethyl (mom) and β-methoxyethoxymethyl (mem) esters. (1981) (7)
Ansa macrolide synthesis preoaration of the aromatic portion of maytansine (1977) (7)
FERRIC CHLORIDE IN ACETIC ANHYDRIDE, A MILD AND VERSATILE REAGENT FOR THE CLEAVAGE OF ETHERS (1975) (6)
Synthesis of cyathiformines A-C: Unusual fungal metabolites derived from chorismic acid (1994) (6)
A REGIOSELECTIVE, CHEMOENZYMATIC SYNTHESIS OF SUCROSE-1 '-METHACRYLATE (1993) (6)
LITHIUM AND POTASSIUM TRIALKYLBOROHYDRIDES. REAGENTS FOR DIRECT REDUCTION OF α,β-UNSATURATED CARBONYL COMPOUNDS TO SYNTHETICALLY VERSATILE ENOLATE ANIONS (1976) (6)
Design and Synthesis of D-Ribofuranoamidrazones as Inhibitors of Nucleoside Processing Enzymes (1995) (6)
Multicomponent reaction design: a one-pot route to substituted di-O-acylglyceric acid amides from α-diazoketones (2008) (6)
Oxidation of bicyclic oxazolines: applications to glycomimetics and novel saccharide derivatives (2002) (6)
Chorismate mutase/prephenate dehydratase from Escherichia coli : subcloning, overproduction and purification (1991) (6)
BIOLOGICAL SPIN LABELS AS ORGANIC REAGENTS, OXIDATION OF ALCOHOLS TO CARBONYL COMPOUNDS USING NITROXYLS (1975) (6)
Studies on the distribution of oligodeoxynucleotide charge states in the gas phase by ion spray mass spectrometry (1995) (6)
What about BOB? A synthetically useful protecting group (2000) (6)
Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase. (2005) (5)
A Simple, General Synthesis of Carbonimidic Dichlorides. (2012) (5)
Polyhydroxylated aziridinylcyclopentanes as glycomimetics: a new competitive inhibitor of α-mannosidase (2001) (5)
Trifluoroacetylation of alcohols: a newly detected reaction of CF3CO3H (1978) (5)
An engineered chorismate mutase with allosteric regulation. (2003) (5)
Thermodynamics of a transition state analogue inhibitor binding to Escherichia coli chorismate mutase: probing the charge state of an active site residue and its role in inhibitor binding and catalysis. (1998) (5)
Electrophilic Azide Transfer to Chiral Enolates: A General Approach to the Asymmetric Synthesis of α-Amino Acids (1989) (5)
A new method for transforming primary amines into phosphoric acid monoesters1 (1991) (5)
Studies on the Biginelli Reaction: A Mild and Selective Route to 3,4-Dihydropyrimidin-2(1H)-ones via Enamine Intermediates. (2006) (4)
Pseudoceratidine, a Marine Natural Product with Antifouling Activity: Synthesis and Biological Studies. (1998) (4)
The hydrolysis of amines to alcohols: Clues from chorismate processing enzymes (1995) (4)
The importance of initial response during outbreaks: A perspective from observations on COVID-19 (2020) (4)
Purple benzene revisited (1980) (4)
A Discriminating Protecting Group Strategy for Alcohols and Amines (1991) (4)
Studies on the oxidation of imino ethers (1983) (4)
A selective inhibitor of Escherichia coli prephenate dehydratase. (2001) (4)
Paclitaxel from Primary Taxanes: A Perspective on Creative Invention in Organozirconium Chemistry (2007) (4)
Transition-State Analogue Inhibitors of Chorismate Mutase. (1990) (4)
Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. (2011) (4)
Asymmetric Total Synthesis of (-)-α-Kainic Acid Using an Enantioselective, Metal-Promoted Ene Cyclization. (2001) (4)
Tandem Multicomponent/Click Reactions: Synthesis of Functionalized Oxazoles and Tetrazoles from Acyl Cyanides. (2007) (3)
A Practical and Inexpensive “Convertible” Isonitrile for Use in Multicomponent Reactions. (2011) (3)
Amidine, Amidrazone, and Amidoxime Derivatives of Monosaccharide Aldonolactams: Synthesis and Evaluation as Glycosidase Inhibitors. (2010) (3)
Synthesis of hydroxamic acids by reductive rearrangement of oximinoesters (1976) (3)
5.14 – Catalysis by Chorismate Mutases (1999) (3)
Enantioselective synthesis of (−)-methyl 5-lactylshikimate lactone (1990) (3)
What about Science for Nonscientists (1993) (3)
Chemistry and Reactivity of α-Substituted Ketones in Isonitrile-Based Multicomponent Reactions. (2009) (3)
Synthesis of Methyl 5-(N-Benzoyl-N- methylamino)-2-methylpenta-2,4-dienoate by Ring-Opening Acylation of an N-Alkyltetrahydropyridine. (1997) (3)
Diels-Alder reactions of trans,trans-1,4 diacetoxybutadiene. Observations concerning some literature reports (1976) (3)
A mild method for extracting amines under neutral conditions (1987) (3)
Heterocyclic routes to polysubstituted cyclopentanes: Molecular modelling of electrophilic additions to di- and trisubstituted cyclopentenes (1996) (3)
Synthesis of 3-hydroxyspermidine: An unusual polyamine constituent of cytotoxic marine compounds (1995) (3)
Metal-mediated Variants of the Passerini Reaction: A New Synthesis of 4-Cyanooxazoles (2002) (3)
An Approach to 6-Oxygenated Shikimic Acid Derivatives by Photolysis of the Pyruvate Ester of Dimethyl Epoxychorismate (1994) (3)
Detecting noncovalent interactions: new frontiers for mass spectrometry. (1993) (2)
A New Family of Five-Carbon Iminoalditols which are Potent Glycosidase Inhibitors. (1991) (2)
Conversion of Amines to Phospho Esters: Decyl Diethyl Phosphate (2003) (2)
Synthesis of cytotoxic spermidine metabolites from the soft coral Sinularia brongersmai (1980) (2)
SELENIUM IN SYNTHESIS. CONJUGATED VINYLIC ETHERS, ESTERS, AND HALIDES FROM α-HETERO-SUBSTITUTED SELENIDES (1978) (2)
Synthesis of (+)-1,5-dideoxy-1,5-imino-D-galactitol, a potent alpha-D-galactosidase inhibitor. (1987) (2)
The Mechanism of the Claisen Rearrangement: Deja-vu All Over Again (1996) (2)
EFFICIENT PREPARATION OF ENANTIOMERICALLY PURE CYCLIC AMINOALDITOLS, TOTAL SYNTHESIS OF 1-DEOXYNOJIRIMYCIN AND 1-DEOXYMANNOJIRIMYCIN (1985) (2)
Glycomimetics That Inhibit Carbohydrate Metabolism (2005) (2)
Inhibitors of Carbohydrate-Processing Enzymes: Design and Synthesis of Sugar-Shaped Heterocycles (1996) (2)
NEIGHBORING GROUP EFFECTS IN THE REGIOSELECTIVE CYCLIZATION OF VICINAL TRANS-1,2-BROMOHYDRINS TO EPOXIDES (1998) (2)
Mechanism of Rearrangement of Chorismic Acid and Related Compounds. (1987) (1)
A General Synthesis of 2‐Substituted‐5‐aminooxazoles: Building Blocks for Multifunctional Heterocycles. (2003) (1)
Alkylation of β-(Hydroxymethyl)pyrroles: A New Synthesis of Porphobilinogen and Other Trisubstituted Pyrroles for Photodynamic Therapy. (1997) (1)
SHIKIMATE-DERIVED METABOLITES. 14. CHIRAL SYNTHESIS OF 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE (1985) (1)
3‐Trimethylsilyl‐3‐Buten‐2‐one: A Michael acceptor (2003) (1)
Studies on Morpholinosphingolipids: Potent Inhibitors of Glucosylceramide Synthase. (1994) (1)
Total Synthesis of (.+-.)-Allosamizoline from a Symmetric Trisubstituted Cyclopentene. (2010) (1)
Terminology: Helping students cope with name reactions in organic chemistry (1990) (1)
Advances in the Chemistry of 2,3-Epoxy Alcohols. New Methodology for Contra- Trans-Diaxial Opening and Selective Enediol Oxidation. (1986) (1)
Short Chemical Synthesis of (-)-Chorismic Acid from (-)-Shikimic Acid. (1991) (1)
[70] Preparation of thermospermine (1983) (1)
A Practical Synthesis of Isocyanates from Isonitriles: Ethyl 2-Isocyanatoacetate. (2014) (1)
Chemistry of Naturally Occurring Polyamines. Part 10. Nonmetabolizable Derivatives of Spermine and Spermidine. (1987) (1)
3‐Trimethylsilyl‐3‐Buten‐2‐One as Michael Acceptor for Conjugate Addition‐Annelation: cis‐4,4a,5,6,7,8‐Hexahydro‐4a,5‐Dimethyl‐2(3H)‐Naphthalenone (2003) (1)
Fabrication of patterned organic thin film by low-energy electron beam lithography and surface-initiated ring-opening metathesis polymerization (2006) (1)
Enantioselective Approaches to Aminocyclopentitols: A Total Synthesis of (+)-6-Epitrehazolin and a Formal Total Synthesis of (+)-Trehazolin. (2010) (1)
Metal‐Mediated Variants of the Passerini Reaction: A New Synthesis of 4‐Cyanooxazoles. (2003) (1)
MECHANISM AND SYNTHETIC UTILITY OF BORON TRIFLUORIDE ETHERATE-PROMOTED ORGANOLITHIUM ADDITIONS (1984) (1)
Is There Another Common Intermediate Beyond Chorismic Acid in the Shikimate Pathway? Synthesis of trans-3-((1-Carboxyvinyl)oxy)-6- hydroxycyclohexa-1,4-diene-1-carboxylic Acid. (2010) (1)
SHIKIMATE-DERIVED METABOLITES. PART 8. A NEW PROTECTING GROUP FOR AMINES. SYNTHESIS OF ANTICAPSIN FROM L-TYROSINE (1981) (1)
A New Approach to Four- and Five-Component Ugi Condensations Starting from Nitriles. (2006) (1)
Studies on the synthesis of amidoximes from nitroalkanes. (2011) (1)
Three-Component Condensation Leading to β-Amino Acid Diamides: Convergent Assembly of β-Peptide Analogues. (2005) (1)
A New Approach to Porphobilinogen and Its Analogues. (1997) (1)
SHIKIMATE DERIVED METABOLITES. PART 8. CATALYZED INSERTION REACTIONS OF SUBSTITUTED α-DIAZOESTERS. A NEW SYNTHESIS OF CIS-ENOATES (1982) (1)
Structure and Total Synthesis of HF‐7, a Neuroactive Glyconucleoside Disulfate from the Funnel‐Web Spider Hololena curta. (1999) (1)
Spontaneous deoxygenation of N-(3,4-methylenedioxybenzyl)-acetohydroxamic Acid: An exceptionally facile process (1976) (1)
A New Synthesis of the Glyoxalase-I Inhibitor COTC. (2000) (0)
SPONTANEOUS DEOXYGENATION OF N-(3,4-METHYLENEDIOXYBENZYL)-ACETOHYDROXAMIC ACID- AN EXCEPTIONALLY FACILE PROCESS (1976) (0)
3RAR-Dihydroxy-L-proline: A Potent and Specific β-D-Glucuronidase Inhibitor. (1986) (0)
An Enantioselective Synthesis of (‐)‐Allosamidin by Asymmetric Desymmetrization of a Highly Functionalized meso‐Epoxide. (1999) (0)
Chemistry of Naturally Occurring Polyamines. Part 9. Synthesis of Spermidine and Spermine Photoaffinity Labeling Reagents. (1986) (0)
Mechanism of Transition-Metal-Assisted Sodium Borohydride and Lithium Aluminum Hydride Reductions (1986) (0)
Synthesis of 1,4,6-Trideoxy-1,4-Imino-D-Mannitol: A Potent α-Mannosidase Inhibitor. (1986) (0)
SILVER-ASSISTED DIMETHYLSULFOXIDE OXIDATIONS, AN IMPROVED SYNTHESIS OF ALDEHYDES AND KETONES (1974) (0)
A Conversation with David Usher (2012) (0)
A Novel Inhibitor (IX) of Human α‐L‐Fucosidase: Enantioselective Synthesis of L‐Fucoamidrazone. (1994) (0)
A New Class of Endoglycosidase Inhibitors. Studies on Endocellulases. (1989) (0)
Three-component condensation leading to beta-amino acid diamides: convergent assembly of beta-peptide analogues. (2004) (0)
Enantioselective Synthesis of Mannostatin A: A New Glycoprotein Processing Inhibitor. (1991) (0)
TRIFLUOROACETYLATION OF ALCOHOLS- A NEWLY DETECTED REACTION OF TRIFLUOROPERACETIC ACID (1978) (0)
What About BOB? A Synthetically Useful Protecting Group. (2001) (0)
Metal‐Promoted Variants of the Passerini Reaction Leading to Functionalized Heterocycles. (2002) (0)
Synthesis of Methyl 5‐(N‐Benzoyl‐N‐methylamino)‐2‐methylpenta‐2,4‐ dienoate by Ring‐Opening Acylation of an N‐Alkyltetrahydropyridine. (1997) (0)
Synthetic Studies on Mannostatin A and Its Derivatives: A New Family of Glycoprotein Processing Inhibitors. (1994) (0)
On the Structure of Naturally‐Occurring (+)‐Methyl 3,4‐Anhydroshikimate. (1990) (0)
CHEMISTRY OF NATURALLY-OCCURRING POLYAMINES. 4. TOTAL SYNTHESIS OF KUKOAMINE A, AN ANTIHYPERTENSIVE CONSTITUENT OF LYCIUM CHINENSE (1981) (0)
Chelate Selectivity in Chelation-Controlled Allylations. A New Synthesis of Castanospermine and Other Bioactive Indolizidine Alkaloids. (1988) (0)
Cleavage Reactions of Optically Active Secondary Butyl Methyl Ether (2017) (0)
On the mechanism of chorismate mutases: Revisiting structural requirements for catalysis (1997) (0)
SHIKIMATE-DERIVED METABOLITES. PART 9. A COMMENT ON THE REACTIVITY OF METHOXYMETHYL (MOM) AND β-METHOXYETHOXYMETHYL (MEM) ESTERS (1982) (0)
ALPHA-SILYLATED VINYL KETONES, A NEW CLASS OF REAGENTS FOR THE ANNELATION OF KETONES (1973) (0)
PrefaceTetrahedron Prize for creativity in organic chemistry (2005) (0)
VIRGINIAMYCIN M: ABSOLUTE CONFIGURATION AND SYNTHETIC STUDIES (1982) (0)
Synthesis of (‐)‐3‐Homoshikimic Acid and (‐)‐3‐Homoshikimate‐3‐ phosphate. (1993) (0)
Multicomponent Reaction Design: A One-Pot Route to Substituted Di-O-acylglyceric Acid Amides from α-Diazoketones. (2009) (0)
DEVELOPMENT AND APPLICATIONS OF ISONITRILE-BASED MULTICOMPONENT REACTIONS A Dissertation Presented to the Faculty of the Graduate School of Cornell University In Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy by (2009) (0)
Ready Oxidation of Halides to Aldehydes Using Trimethylamine N-Oxide in Dimethylsulfoxide. (1992) (0)
Selective Benzylation of Alcohols and Amines Under Mild Conditions. (1990) (0)
A Conversation with Jerrold Meinwald (2011) (0)
Design and Synthesis of D‐Ribofuranoamidrazones as Inhibitors of Nucleoside Processing Enzymes. (1995) (0)
SYNTHESIS OF HYDROXAMIC ACIDS BY REDUCTIVE REARRANGEMENT OF OXIMINO ESTERS (1976) (0)
New Chemistry of Diazoesters from Thermal Rearrangement of N-Alkyl-N- nitrosoamides. (1991) (0)
Chemistry of Naturally Occurring Polyamines. Part 11. Unsaturated Spermidine and Spermine Derivatives. (1988) (0)
Oxidation of Bicyclic Oxazolines: Applications to Glycomimetics and Novel Saccharide Derivatives. (2002) (0)
Chemistry of Naturally Occurring Polyamines. Part 7. Selective Functionalization of Hydroxyputrescine. Chemistry of Naturally Occurring Polyamines Part 8. Total Synthesis of (+)-Hypusine. (1984) (0)
Detection of Oligonucleotide Duplex Forms by Ion-Spray Mass Spectrometry. (1993) (0)
Stereoselective Fragmentation of a Tricyclic Diester Leading to a Potent Chorismate Mutase Transition State Inhibitor. (1988) (0)
CONJUGATE ADDITION OF 1-TRIALKYLSILYLPROPYNYLCOPPER DERIVATIVES, A NEW SYNTHESIS OF 1,5-ALLENIC AND ACETYLENIC OLEFINS (1975) (0)
SPIROANNELATION OF ENOL ETHERS OF CYCLIC 1,3-DIKETONES, A SIMPLE STEREOSPECIFIC SYNTHESIS OF BETA-VETIVONE (1973) (0)
Rapid and Efficient Reduction of Aliphatic Nitro Compounds to Amines. (1986) (0)
[Therapeutic procedure in the ossification of cephalohematomas]. (1987) (0)
IMPROVED METHODS FOR THE SIDE-CHAIN DEGRADATION OF LANOSTEROL, THE SYNTHESIS OF 4,4,14ALPHA-TRIMETHYL-5ALPHA-PREGN-8-EN-20-ONE DERIVATIVES (1974) (0)
Synthesis of (+)‐1,5‐Dideoxy‐1,5‐imino‐D‐galactitol, a Potent α‐D‐Galactosidase Inhibitor. (1988) (0)
SHIKIMATE-DERIVED METABOLITES. 10. SYNTHETIC STUDIES ON THE BIOSYNTHESIS OF PARA-AMINOBENZOIC ACID (1982) (0)
Synthesis of Cyathiformines A-C: Unusual Fungal Metabolites Derived from Chorismic Acid. (1994) (0)
Additions and Corrections, "Ferric Chloride in Acetic Anhydride. A Mild and Versatile Reagent for the Cleavage of Ethers" (1975) (0)
Reductive Deoxygenation by Cp2ZrHCl: Selective Formation of Imines via Zirconation/Hydrozirconation of Amides. (1993) (0)
Preface to the Tetrahedron Letters 50th Anniversary Special Issue (2009) (0)
DIFFERENTIATION OF DIOLS, A NEW SYNTHESIS OF BROMOFORMATES AND PROTECTED HYDROXYALDEHYDES (1974) (0)
A Short Homochiral Synthesis of Substituted Pyrrolidines. (2010) (0)
A Conversation with Dave Collum (2014) (0)
Synthesis of 2S-Carboxy-3R,4R,5S-trihydroxypiperidine, a Naturally Occurring Inhibitor of β-D-Glucuronidase. (1986) (0)
Dihydropyrimidinone Positive Modulation of Delta Subunit-containing GABA A Receptors, Including an Epilepsy-linked Mutant Variant (2016) (0)
Chapter 4 – Synthetic Studies on Pentacyclic Quassinoids (1991) (0)
ANSA MACROLIDE SYNTHESIS. PREPARATION OF THE AROMATIC PORTION OF MAYTANSINE (1977) (0)
An Approach to 6‐Oxygenated Shikimic Acid Derivatives by Photolysis of the Pyruvate Ester of Dimethyl Epoxychorismate. (1995) (0)
New Four‐Component Condensations Leading to 2,4,5‐Trisubstituted Oxazoles. (2003) (0)
Heterocyclic Routes to Polysubstituted Cyclopentanes: Molecular Modeling of Electrophilic Additions to Di‐ and Trisubstituted Cyclopentenes. (1996) (0)
THE CHEMISTRY OF NATURALLY OCCURRING POLYAMINES. PART 3. SYNTHESIS OF CYTOTOXIC SPERMIDINE METABOLITES FROM THE SOFT CORAL SINULARIA BRONGERSMAI (1980) (0)
Braving the New Biology (1991) (0)
THE CHEMISTRY OF NATURALLY OCCURRING POLYAMINES. 2. A TOTAL SYNTHESIS OF THERMOSPERMINE (1980) (0)
Synthesis of the Antifouling Polyamine Pseudoceratidine and Its Analogues: Factors Influencing Biocidal Activity. (1996) (0)
MASKED ARENES, SYNTHESIS OF SUBSTITUTED BENZENES AND BENZENE OXIDES (1977) (0)
Total Synthesis of Mololipids: A New Series of Anti‐HIV Moloka′iamine Derivatives. (2001) (0)
New Chemistry of Amines. Part 3. New Syntheses of Alkenes and Alkynes from Amines. (1990) (0)
A NEW β-LACTAM SYNTHESIS (1982) (0)
Potent, Broad-Spectrum Inhibition of Glycosidases by an Amidine Derivative of D-Glucose. (1990) (0)
New Chemistry of Amines. Part 2. A Convenient Synthesis of Phosphotriesters from Phosphoramidates. (1990) (0)
Reductive Deoxygenation Using Hydridozirconium Enolates: A New Synthesis of α,β-Unsaturated Esters. (2010) (0)
Purine nucleoside phosphorylase from calf spleen (2005) (0)
New Chemistry of Nitrosoamides. Part 5. A New Method for Transforming Primary Amines into Phosphoric Acid Monoesters. (1992) (0)
Inhibition of Plant Glycosidases by a D-Galacturonic Acid Analog. (1990) (0)
Stereoselective Synthetic Approaches to Highly Substituted Cyclopentanes via Electrophilic Additions to Mono‐, Di‐, and Trisubstituted Cyclopentenes. (2000) (0)
SHIKIMATE‐DERIVED METABOLITES. TOTAL SYNTHESIS OF NOR‐CHORISMIC ACID (1979) (0)
(3R,4R,5S)‐5‐Acetamido‐3,4‐piperidinediol: A Selective Hexosaminidase Inhibitor. (1988) (0)
Going Gently into Flight: Analyzing Noncovalent Interactions by Mass Spectrometry (2003) (0)
Polyhydroxylated Aziridinylcyclopentanes as Glycomimetics: A New Competitive Inhibitor of α‐Mannosidase. (2002) (0)
An Improved Procedure for the Conversion of Amines to Alcohols at Low Temperature. (1990) (0)
Guanidine Anologues of a Deoxysugar. (1995) (0)
A Discriminating Protecting Group Strategy for Alcohols and Amines. (1992) (0)
Synthesis of 3‐Hydroxyspermidine: An Unusual Polyamine Constituent of Cytotoxic Marine Compounds. (1996) (0)
2‐Hydroperoxyhexafluoro‐2‐propanol (2001) (0)
Studies on 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors. (2001) (0)
BORON TRIFLUORIDE ETHERATE PROMOTED ALKYLATION OF AZIRIDINES WITH ORGANOCOPPER REAGENTS: A NEW SYNTHESIS OF AMINES (1985) (0)
ANSA MACROLIDE SYNTHESIS. II. A CONVERGENT APPROACH TO MAYTANSINE (1977) (0)
Aminocyclopentitols from Fulvenes: Syntheses of (+)‐Trehazolin and the Pentasubstituted Cyclopentane of Keruffaride. (2010) (0)
Strategies for Innovation in Multicomponent Reaction Design (2009) (0)
Synthesis of Ceratinamine and Moloka′iamine: Antifouling Agents from the Marine Sponge Pseudoceratina purpurea. (1998) (0)
A ONE-STEP SYNTHESIS OF Γ-PYRONES (1980) (0)
Message from the Chairman of the Executive Board of Editors: Tetrahedron Young Investigator Awards (2005) (0)
A Mild Method for Extracting Amines Under Neutral Conditions. (1988) (0)
An Efficient Synthesis of Substituted Prolines by the Selective Reduction and Reductive Cyanation of 2-Pyrrolidones. (2010) (0)

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