Bruce Lahn
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American geneticist
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Bruce Lahnbiology Degrees
Biology
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#2512
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Genetics
#275
World Rank
#326
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Biology
Bruce Lahn's Degrees
- Bachelors Biology California Institute of Technology
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Why Is Bruce Lahn Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bruce Lahn is a Chinese-born American geneticist. Lahn came to the U.S. from China to continue his education in the late 1980s. He is the William B. Graham professor of Human Genetics at the University of Chicago. He is also the founder of the Center for Stem Cell Biology and Tissue Engineering at Sun Yat-sen University in Guangzhou, China. Lahn currently serves as the chief scientist of VectorBuilder, Inc.
Bruce Lahn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Geometric cues for directing the differentiation of mesenchymal stem cells (2010) (1623)
- Evolutionary and Biomedical Insights from the Rhesus Macaque Genome (2007) (1309)
- Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine (2011) (947)
- Four evolutionary strata on the human X chromosome. (1999) (903)
- Functional coherence of the human Y chromosome. (1997) (824)
- Systematic Comparison of Constitutive Promoters and the Doxycycline-Inducible Promoter (2010) (452)
- Accelerated Evolution of Nervous System Genes in the Origin of Homo sapiens (2004) (439)
- Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans (2005) (418)
- Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens (2005) (351)
- Nestin Is Required for the Proper Self‐Renewal of Neural Stem Cells (2010) (310)
- Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity (2004) (235)
- Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. (2004) (225)
- The human Y chromosome, in the light of evolution (2001) (219)
- Positive selection on the human genome. (2004) (210)
- Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome (1999) (198)
- Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis (2002) (198)
- Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. (2004) (180)
- Genetic links between brain development and brain evolution (2005) (157)
- Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage (2006) (153)
- Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction (2014) (118)
- Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells (2008) (112)
- How mammalian sex chromosomes acquired their peculiar gene content. (2004) (111)
- The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. (2007) (99)
- Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception. (2003) (94)
- A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins. (2000) (93)
- Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. (2014) (93)
- Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. (2006) (92)
- Genetic basis of human brain evolution (2008) (90)
- A genome-wide screen for noncoding elements important in primate evolution (2008) (88)
- Nestin expression in different tumours and its relevance to malignant grade (2007) (86)
- Apaf-1 deficiency and neural tube closure defects are found in fog mice (2001) (83)
- The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. (2003) (78)
- Response to Comment on "Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens" and "Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans" (2006) (69)
- Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells (2007) (67)
- Protecting against wayward human induced pluripotent stem cells with a suicide gene. (2012) (65)
- Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming. (2012) (62)
- Trak1 mutation disrupts GABAA receptor homeostasis in hypertonic mice (2006) (59)
- Genic mutation rates in mammals: local similarity, chromosomal heterogeneity, and X-versus-autosome disparity. (2003) (55)
- Robust signals of coevolution of interacting residues in mammalian proteomes identified by phylogeny-aided structural analysis (2005) (51)
- A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate. (2005) (50)
- Nestin(+) kidney resident mesenchymal stem cells for the treatment of acute kidney ischemia injury. (2015) (49)
- Xq–Yq interchange resulting in supernormal X-linked gene expression in severely retarded males with 46,XYq- karyotype (1994) (48)
- Generation of functional hepatocytes from mouse induced pluripotent stem cells (2009) (47)
- Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. (2012) (39)
- A genetic legacy from archaic Homo. (2008) (39)
- Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates. (2006) (38)
- Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. (2006) (37)
- Systematically assessing the influence of 3-dimensional structural context on the molecular evolution of mammalian proteomes. (2006) (36)
- Localized methylation in the key regulator gene endothelin‐1 is associated with cell type‐specific transcriptional silencing (2006) (34)
- TALEN-based generation of a cynomolgus monkey disease model for human microcephaly (2016) (34)
- Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome (1999) (32)
- Why the y is So Weird. (2001) (32)
- Expression of nestin in lymph node metastasis and lymphangiogenesis in non-small cell lung cancer patients. (2010) (32)
- Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell (2006) (31)
- Selective Constraint on Noncoding Regions of Hominid Genomes (2005) (30)
- The radial glia antibody RC2 recognizes a protein encoded by Nestin. (2009) (30)
- Effects of chromosomal rearrangements on human-chimpanzee molecular evolution. (2004) (29)
- Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host. (2008) (29)
- Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells. (2013) (29)
- Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test (2010) (27)
- Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. (2009) (25)
- The X chromosome: not just her brother's keeper (2005) (24)
- Multiple independent origins of sex chromosomes in amniotes (2006) (22)
- A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway. (2006) (21)
- Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells (2008) (20)
- Let's celebrate human genetic diversity (2009) (20)
- Motoneuron-specific NR3B gene (2008) (19)
- Systematic identification of cis-silenced genes by trans complementation (2008) (19)
- A Stem Cell-Based Tool for Small Molecule Screening in Adipogenesis (2010) (18)
- Diverse fates of paralogs following segmental duplication of telomeric genes. (2004) (18)
- Efficient Genetic Modification of Cynomolgus Monkey Embryonic Stem Cells with Lentiviral Vectors (2010) (13)
- Slower cycling of nestin-positive cells in neurosphere culture (2006) (12)
- Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells (2014) (12)
- Response to Comments by Timpson et al. and Yu et al. (2007) (12)
- The Evolution of Word Composition in Metazoan Promoter Sequence (2006) (11)
- Chromatin analysis of occluded genes (2009) (11)
- The “occlusis” model of cell fate restriction (2011) (10)
- Evidence for a critical role of gene occlusion in cell fate restriction (2011) (10)
- SPEED: a molecular-evolution-based database of mammalian orthologous groups (2006) (10)
- Uncovering the mutation-fixation correlation in short lineages (2007) (10)
- Hereditary hyperekplexia caused by novel mutations of GLRA1 in Turkish families (2012) (10)
- Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice (2016) (9)
- What makes us human: revisiting an age-old question in the genomic era (2006) (7)
- Mathematical models for the proliferation of neural stem/progenitor cells in clonogenic culture. (2007) (7)
- Involvement of extracellular factors in maintaining self-renewal of neural stem cell by nestin (2014) (7)
- Different classes of tissue-specific genes show different levels of noncoding conservation. (2006) (7)
- Establishment and characterization of two new human embryonic stem cell lines, SYSU-1 and SYSU-2. (2007) (5)
- Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. (2006) (3)
- Social dominance hierarchy: toward a genetic and evolutionary understanding (2020) (3)
- Chromosome Four Evolutionary Strata on the Human X (2008) (3)
- Isolation, characterization and gene modification of fetal neural stem/progenitor cells from cynomolgus monkey (2008) (2)
- Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro (2010) (2)
- A versatile tool for tracking the differentiation of human embryonic stem cells (2010) (2)
- Corrigendum: Trak1 mutation disrupts GABAA receptor homeostasis in hypertonic mice (2006) (1)
- Development of the Replica Barcode Selection Technology for the Study of Breast Cancer Metastasis (2012) (0)
- Mammalian Sex Chromosomes Evolution in Cooper d.N. (2003) (0)
- Social dominance hierarchy: toward a genetic and evolutionary understanding (2020) (0)
- Distribution of Cytoskeleton Protein Nestin in Acute Leukemia. (2009) (0)
- The human Y chromosome : gene content and chromosomal abnormalities (1998) (0)
- Capacity to erase gene occlusion is a defining feature distinguishing naive from primed pluripotency (2021) (0)
- Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma (2012) (0)
- The X resembles any other chromosome , but the Y — the source of maleness — is downright strange . How did the two come to differ so much ? (2001) (0)
- Viable interspecies chimeras created by injection of Apodemus embryonic stem cells into Mus blastocysts (2008) (0)
- Authors' Reply (2006) (0)
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