Bruce William Stillman

Bruce William Stillman's AcademicInfluence.com Rankings

Biology

#556

World Rank

#982

Historical Rank

Biochemistry

#305

World Rank

#372

Historical Rank

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Biology

Why Is Bruce William Stillman Influential?

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According to Wikipedia, Bruce William Stillman, AO, FAA, FRS is a biochemist and cancer researcher who has served as the Director of Cold Spring Harbor Laboratory since 1994 and President since 2003. He also served as the Director of its NCI-designated Cancer Center for 25 years from 1992 to 2016. During his leadership, CSHL has been ranked as the No. 1 institution in molecular biology and genetics research by Thomson Reuters. Stillman's research focuses on how chromosomes are duplicated in human cells and in yeast Saccharomyces cerevisiae; the mechanisms that ensure accurate inheritance of genetic material from one generation to the next; and how missteps in this process lead to cancer. For his accomplishments, Stillman has received numerous awards, including the Alfred P. Sloan, Jr. Prize in 2004 and the 2010 Louisa Gross Horwitz Prize, both of which he shared with Thomas J. Kelly of Memorial Sloan-Kettering Cancer Center, as well as the 2019 Canada Gairdner International Award for biomedical research, which he shared with John Diffley.

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Bruce William Stillman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA (1994) (1771)
ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex (1992) (1218)
Cold Spring Harbor Laboratory (1995) (1189)
Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein (1987) (1014)
Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late Mitosis (2000) (934)
The DNA replication fork in eukaryotic cells. (1998) (830)
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair (1994) (699)
Replication-Dependent Marking of DNA by PCNA Facilitates CAF-1-Coupled Inheritance of Chromatin (1999) (665)
Nucleosome Assembly by a Complex of CAF-1 and Acetylated Histones H3/H4 (1996) (646)
A yeast chromosomal origin of DNA replication defined by multiple functional elements. (1992) (613)
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro (1989) (611)
The Knockout Mouse Project (2004) (574)
Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro (1994) (557)
Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. (1997) (550)
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication (2009) (516)
FASCIATA Genes for Chromatin Assembly Factor-1 in Arabidopsis Maintain the Cellular Organization of Apical Meristems (2001) (469)
Yeast origin recognition complex functions in transcription silencing and DNA replication. (1993) (436)
p62 dok : A Constitutively Tyrosine-Phosphorylated, GAP-Associated Protein in Chronic Myelogenous Leukemia Progenitor Cells (1997) (408)
The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro (1987) (407)
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. (1997) (400)
Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. (1997) (385)
Reconstitution of complete SV40 DNA replication with purified replication factors. (1994) (376)
Assembly of a Complex Containing Cdc45p, Replication Protein A, and Mcm2p at Replication Origins Controlled by S-Phase Cyclin-Dependent Kinases and Cdc7p-Dbf4p Kinase (2000) (371)
The p150 and p60 subunits of chromatin assemblyfactor I: A molecular link between newly synthesized histories and DNA replication (1995) (370)
Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs (2010) (368)
Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA (2003) (367)
ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome (1995) (364)
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. (1998) (356)
Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin (1990) (353)
Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. (2006) (352)
Chromatin Assembly Coupled to DNA Repair: A New Role for Chromatin Assembly Factor I (1996) (346)
Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins. (1991) (342)
Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase (1998) (340)
Histone Acetyltransferase HBO1 Interacts with the ORC1 Subunit of the Human Initiator Protein* (1999) (335)
Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. (2002) (333)
Cellular factors required for multiple stages of SV40 DNA replication in vitro. (1988) (324)
A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase. (2000) (323)
Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells (1985) (322)
Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA (1988) (321)
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 (2009) (316)
Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. (1999) (312)
Cdc7p–Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway (1999) (298)
PCNA connects DNA replication to epigenetic inheritance in yeast (2000) (296)
Principles and concepts of DNA replication in bacteria, archaea, and eukarya. (2013) (291)
Smart machines at the DNA replication fork (1994) (291)
Deregulation of cyclin E in human cells interferes with prereplication complex assembly (2004) (289)
The Biology of Plants (2012) (288)
Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells. (1990) (280)
Initiation of eukaryotic DNA replication in vitro. (1988) (278)
Stepwise assembly of chromatin during DNA replication in vitro. (1991) (277)
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. (1998) (277)
The multidomain structure of Orc1 p reveals similarity to regulators of DNA replication and transcriptional silencing (1995) (276)
Cell Cycle Control of DNA Replication (1996) (270)
A Proposal for a Coordinated Effort for the Determination of Brainwide Neuroanatomical Connectivity in Model Organisms at a Mesoscopic Scale (2009) (264)
cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication. (1992) (262)
Conserved Initiator Proteins in Eukaryotes (1995) (257)
Characterization of the five replication factor C genes of Saccharomyces cerevisiae (1995) (257)
Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance (2005) (257)
Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo (2003) (250)
Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. (2012) (249)
A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria. (1991) (247)
Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics. (2007) (244)
Chromatin assembly during SV40 DNA replication in vitro (1986) (244)
Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. (1991) (241)
ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA (2005) (238)
Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase. (1991) (237)
Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug (2009) (232)
Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication (1989) (228)
Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins. (2003) (226)
Orc6 Involved in DNA Replication, Chromosome Segregation, and Cytokinesis (2002) (223)
An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication. (1993) (220)
The origin recognition complex in silencing, cell cycle progression, and DNA replication. (1995) (219)
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. (1990) (215)
The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators. (1995) (212)
Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex (1992) (206)
Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer. (1988) (188)
Yph1p, an ORC-Interacting Protein Potential Links between Cell Proliferation Control, DNA Replication, and Ribosome Biogenesis (2002) (187)
The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin. (1999) (186)
Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and delta. (1989) (185)
Identification of the gene and mRNA for the adenovirus terminal protein precursor (1981) (184)
Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro (1989) (182)
CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication (1997) (181)
A single‐stranded DNA binding protein required for mitochondrial DNA replication in S. cerevisiae is homologous to E. coli SSB. (1992) (179)
Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. (2010) (170)
DNA binding properties of an HMG1-related protein from yeast mitochondria. (1992) (164)
A human protein related to yeast Cdc6p. (1997) (163)
Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage (1996) (155)
Similarity between the transcriptional silencer binding proteins ABF1 and RAP1. (1989) (153)
Functional conservation of multiple elements in yeast chromosomal replicators (1994) (148)
Orc1 Controls Centriole and Centrosome Copy Number in Human Cells (2009) (148)
Origin recognition and the chromosome cycle (2005) (144)
Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA (1984) (143)
Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae (2007) (137)
T antigen and template requirements for SV40 DNA replication in vitro. (1985) (136)
Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA (2013) (135)
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization (2010) (127)
Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro. (2000) (121)
Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replication (1982) (112)
Cellular Proteins Required for Adeno-Associated Virus DNA Replication in the Absence of Adenovirus Coinfection (1998) (110)
The replication of adenovirus DNA with purified proteins (1983) (109)
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 (2017) (107)
Histone Modifications: Insights into Their Influence on Gene Expression (2018) (107)
The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents (2009) (105)
Regulation of SV40 DNA replication by phosphorylation of T antigen. (1987) (104)
Structure and function of the BAH‐containing domain of Orc1p in epigenetic silencing (2002) (102)
Function of adenovirus terminal protein in the initiation of DNA replication. (1982) (100)
Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function (2014) (98)
Cdc6 ATPase Activity Regulates ORC·Cdc6 Stability and the Selection of Specific DNA Sequences as Origins of DNA Replication* (2007) (97)
The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p* (1998) (95)
Replication-Coupled Chromatin Assembly Generates a Neuronal Bilateral Asymmetry in C. elegans (2011) (95)
Replicator dominance in a eukaryotic chromosome. (1994) (94)
Simian virus 40 large T antigen binds to topoisomerase I. (1996) (93)
DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. (2012) (92)
Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1 (1996) (91)
Opening of the Clamp An Intimate View of an ATP-Driven Biological Machine (2001) (91)
Dynamics of pre-replication complex proteins during the cell division cycle. (2004) (86)
Nuclear envelope localization of an adenovirus tumor antigen maintains the integrity of cellular DNA (1984) (84)
Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA. (1982) (83)
Cyclin-Dependent Kinase Inhibitor p21 Modulates the DNA Primer-Template Recognition Complex (1998) (81)
cDNAs encoding the large subunit of human replication factor C. (1993) (81)
Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation (1989) (81)
DNA polymerases at the replication fork in eukaryotes. (2008) (78)
The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae (2008) (78)
ATP-dependent Assembly of the Human Origin Recognition Complex*♦ (2007) (78)
Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle (2001) (75)
The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1- mediated nucleosome assembly onto replicated DNA in vitro. (2000) (74)
A common telomeric gene silencing assay is affected by nucleotide metabolism. (2011) (72)
The initiation of chromosomal DNA replication in eukaryotes. (1990) (71)
Conserved Sequences at the Origin of Adenovirus DNA Replication (1982) (70)
Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication. (2012) (69)
Initiation of chromosomal DNA replication in eukaryotes. Lessons from lambda. (1994) (69)
Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopy. (2012) (69)
Expression of adenovirus E1B mutant phenotypes is dependent on the host cell and on synthesis of E1A proteins (1987) (69)
Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. (1999) (69)
Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model (2017) (67)
Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro. (1991) (64)
Rhabdomyosarcoma: current challenges and their implications for developing therapies. (2014) (63)
Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression (2014) (61)
Reconstitution of Recombinant Human Replication Factor C (RFC) and Identification of an RFC Subcomplex Possessing DNA-dependent ATPase Activity* (1998) (61)
Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. (2011) (61)
Activation of Chromosomal DNA Replication inSaccharomyces cerevisiae by Acidic Transcriptional Activation Domains (1998) (60)
Initiation of adenovirus DNA replication in vitro requires a specific DNA sequence. (1983) (59)
Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model (2016) (59)
DNA sequences required for the in vitro replication of adenovirus DNA. (1984) (56)
Reversible suppression of an essential gene in adult mice using transgenic RNA interference (2011) (56)
The DNA-binding domain of simian virus 40 tumor antigen has multiple functions (1993) (56)
Analysis of a protein-binding domain of p53 (1993) (56)
Transcriptional silencing and lamins (1989) (54)
Interaction of a nuclear factor with the polyomavirus enhancer region. (1986) (53)
Regulation of adenovirus gene expression in human WI38 cells by an E1B-encoded tumor antigen (1986) (53)
Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes. (2015) (52)
Drosophila proliferating cell nuclear antigen. Structural and functional homology with its mammalian counterpart. (1990) (49)
A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria (1991) (49)
Initiation of eukaryotic DNA replication in vitro (1988) (48)
Role of the adenovirus E1B 19,000-dalton tumor antigen in regulating early gene expression (1988) (46)
DNA replication and the cell cycle. (1992) (45)
Structure of the active form of human origin recognition complex and its ATPase motor module (2017) (45)
The origin recognition complex: a biochemical and structural view. (2012) (45)
Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing. (2005) (43)
Organization and expression of the left third of the genome of adenovirus. (1980) (43)
Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system. (1995) (42)
Purification of DNA polymerase delta as an essential simian virus 40 DNA replication factor. (1991) (41)
Adenovirus DNA replication in vitro: a protein linked to the 5' end of nascent DNA strands (1981) (40)
Nuclear DNA synthesis in vitro is mediated via stable replication forks assembled in a temporally specific fashion in vivo (1988) (39)
Functions of the adenovirus E1B tumour antigens. (1986) (39)
Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells* (2015) (35)
An adenovirus protein associated with the ends of replicating DNA molecules. (1979) (34)
Functions of Sensor 1 and Sensor 2 Regions of Saccharomyces cerevisiae Cdc6p in Vivo and in Vitro * (2002) (33)
Acquired dependence of acute myeloid leukemia on the DEAD-box RNA helicase DDX5. (2014) (32)
Initiation of chromosome replication in eukaryotic cells. (1992) (32)
An Analysis of CAF-1-interacting Proteins Reveals Dynamic and Direct Interactions with the KU Complex and 14-3-3 Proteins* (2011) (30)
Simian virus 40 origin- and T-antigen-dependent DNA replication with Drosophila factors in vitro (1994) (29)
Comparison of DNA replication in cells from prokarya and eukarya (1996) (29)
ABF1-binding Sites Promote Efficient Global Genome Nucleotide Excision Repair* (2009) (29)
Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 (2020) (29)
The origin of adenovirus DNA replication. (1984) (29)
Replicator renaissance (1993) (28)
Identification of cellular components required for SV40 DNA replication in vitro. (1988) (27)
Purification of a cellular, double-stranded DNA-binding protein required for initiation of adenovirus DNA replication by using a rapid filter-binding assay (1986) (27)
Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression (2015) (26)
p53-induced p21 controls DNA replication. (1997) (25)
Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replication (1989) (25)
Large-scale biomedical science. Exploring strategies for future research (2003) (23)
Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes (2013) (23)
Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen. (1989) (23)
Replication Factors Required for SV 40 DNA Replication in Vitro (2001) (23)
The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592 (2018) (23)
Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription (2016) (21)
Phosphorylation of replication protein A: a role for cdc2 kinase in G1/S regulation. (1991) (21)
Genomic Views of Genome Duplication (2001) (19)
Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication. (2021) (18)
Characterization of Group B Colicin-Resistant Mutants of Escherichia coli K-12: Colicin Resistance and the Role of Enterochelin (17)
Replication of linear adenovirus DNA is not hairpin-primed (1977) (16)
The dynamic nature of the human origin recognition complex revealed through five cryoEM structures (2020) (15)
Replication of DNA in adenovirus-infected cells. (1979) (15)
Evolution of DNA replication origin specification and gene silencing mechanisms (2020) (14)
Purification and Characterization of a Replication-Dependent Chromatin Assembly Factor Isolated from Human Cells (1989) (14)
Meselson, Stahl and the Replication of DNA: A History of “The Most Beautiful Experiment in Biology” (2002) (14)
DDX 5 Regulates DNA Replication and Is Required for Cell Proliferation in a Subset of Breast Cancer Cells (2012) (13)
The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6 (2021) (13)
Adenoviral DNA replication: DNA sequences and enzymes required for initiation in vitro. (1983) (12)
Identification of multiple cellular factors required for SV40 replication in vitro. (1987) (12)
Functional characterization of thermolabile DNA-binding proteins that affect adenovirus DNA replication (1986) (12)
The Genome of Homo Sapiens (2003) (11)
SV40 DNA Replication (1992) (11)
Replication of SV40 in vitro using proteins derived from a human cell extract (1989) (11)
Support for the Human Cancer Genome Project (2005) (11)
DNA-Protein Interactions at the Replication Origins of Adenovirus and Sv-40 (1986) (11)
A structural view of the initiators for chromosome replication. (2018) (10)
Structure and Function of the BAH-containing Domain of Orc 1 p in Epigenetic Silencing (2002) (10)
The replicon model and eukaryotic chromosomes. (1993) (10)
Control and Regulation of Stem Cells (2008) (9)
Independent Mutations in Ad2tslll Cause Degradation of Cellular DNA (9)
Jason W (2006) (9)
Immunity and Tolerance (2013) (9)
Duplication of DNA in eukaryotic cells (2006) (9)
Erratum: Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance (EMBO Journal (2004) 23 (2657-2663) (10.1038/sj.emboj.7600255)) (2005) (9)
Biochemical and Genetic Analysis of Adenovirus DNA Replication In Vitro (1985) (9)
Clocks and Rhythms (2007) (8)
Immunoblotting histones from yeast whole-cell protein extracts. (2013) (8)
The replication of adenovirus DNA (1983) (7)
The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure (2020) (7)
Origins of DNA replication in eukaryotes. (2023) (7)
Initiation of Eukaryotic DNA-Replication (1994) (6)
The Third World Comes of Age (2008) (6)
A close relative of the nuclear , chromosomal high-mobility group protein HMG 1 in yeast mitochondria ( Saccharomyces cerevisiael / DNA-binding protein / repicaton / transcwption / HMG box ) (6)
Protein kinesis : the dynamics of protein trafficking and stability : abstracts of papers presented at the LX Cold Spring Harbor Symposium on Quantitative Biology, May 31-June 7, 1995 (1995) (6)
Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication (1984) (6)
The remarkable gymnastics of ORC (2022) (6)
DNA replication. Replicator renaissance. (1993) (6)
Functions of replication factor C and proliferating-cell nuclear antigen : Functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T 4 ( simian virus 40 DNA replication / DNA binding / ATPase / evolution ) (6)
A Single-Stranded-DNA Binding-Protein Required for Mitochondrial-DNA Replication in Saccharomyces-Cerevisiae Is Homologous to Escherichia-Coli Ssb (1992) (5)
assembly and function 7 double-hexamer − Structural and mechanistic insights into Mcm 2 Material Supplemental (2014) (5)
Cyclin binding Cy motifs have multiple activities in the initiation of DNA replication (2019) (4)
Interactions between Purified Cellular Proteins and Yeast Origins of DNA Replication (1988) (4)
Eukaryotic DNA replication (1988) (4)
The ribosome : abstracts of papers presented at the LXVI Cold Spring Harbor Symposium on Quantitative Biology, May 31-June 5, 2001 (2001) (3)
Human-Saccharomyces cerevisiae Proliferating Cell Nuclear Antigen Hybrids (2001) (3)
Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters (2021) (3)
Characterization of Cellular Proteins Required for Sv40 DNA Replication in-Vitro (1988) (2)
genes of Saccharomyces cerevisiae. Characterization of the five replication factor C (2012) (2)
The cell surface (1992) (2)
Molecular Approaches to Controlling Cancer (2005) (2)
Abstracts of papers presented at the Sixth Cold Spring Harbor Meeting on Cancer Cells Eukaryotic DNA Replication, September 2-September 6, 1987 (1987) (2)
The initiation of DNA replication in the yeast Saccharomyces cerevisiae (1996) (2)
Mechanism and regulation of eukaryotic DNA replication (1991) (2)
Developing Therapies Rhabdomyosarcoma : Current Challenges and Their Implications for (2014) (1)
Biological responses to DNA damage : abstracts of papers presented at the LXV Cold Spring Harbor Symposium on Quantitative Biology, May 31 - June 5, 2000 (2000) (1)
Report of the National Neurofibromatosis Foundation (NNFF) Task Force on Treatment of Neurofibromatosis 1 (1997) (1)
Abstracts of papers presented at the LXII Cold Spring Harbor Symposium on Quantitative Biology : pattern formation during development, May 28-June 2, 1997 (1997) (1)
Abstracts of papers presented at the LVIII Cold Spring Harbor Symposium on Quantitative Biology, DNA & chromosomes, June 2-June 9, 1993 (1993) (1)
HPV-16 E 7 ? oncoprotein Inhibition of CDK activity and PCNA-dependent DNA replication (1997) (1)
The stem cell decision: is this human? (2001) (1)
Evolution: The Molecular Landscape (2009) (1)
Cdc6 ATPase Activity Regulates ORCCdc6 Stability and the Selection of Specific DNA Sequences as Origins (2007) (1)
Mechanisms of transcription : abstracts of papers presented a the LXIII Cold Spring Harbor Symposium on Quantitative Biology (1998) (1)
virus 40 DNA replication in vitro . of leading and lagging strands during simian synthesisRF-C , that is required for coordinated Purification of a cellular replication factor (1)
FAS1,FAS2 and AtMSI1 proteins form a complex which has chromatin assembly activity in vitro (2001) (1)
Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance (1)
Molecular Mechanisms in Biological Processes (2005) (1)
Stillman assembly factor-I . silencing in Saccharomyces cerevisiae cells lacking chromatin Ultraviolet radiation sensitivity and reduction of telomeric (2007) (0)
Deregulation of Cyclin E and Genomic Instability (2005) (0)
The Origin Recognition Complex: where it all begins (2018) (0)
identification of multiple stages of initiation . Simian virus 40 DNA replication in vitro (0)
Metabolism and Disease (2011) (0)
Transcriptional Silencing, DNA-Replication, and the Yeast Origin Recognition Complex (1994) (0)
Initiation of DNA replication - Assembly of a molecular machine depends on origin DNA (2007) (0)
DNA. cellular tumor antigen maintains the integrity of Nuclear envelope localization of an adenovirus (2013) (0)
The cardiovascular system : abstracts of papers presented at the LXVII Cold Spring Harbor Symposium on Quantitative Biology, May 29-June 3, 2002 (2002) (0)
Talk from Bruce Stillman at the Cold Spring Harbor LaboratoryIn-House Symposium (2011) (2011) (0)
Replication of human adenovirus DNA (1979) (0)
DNA replication and the cell cycle DNA replication in vitro , but it is not essential ( Virshup and Kelly (2007) (0)
Function & dysfunction in the nervous system : abstracts of papers presented at the LXI Cold Spring Harbor Symposium on Quantitative Biology, May 29-June 5, 1996 (1996) (0)
Decision letter: Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase (2020) (0)
In vitro reconstitution of budding yeast pre-RC, competent in recruitment of recombinant pre-IC components, using purified, recombinant proteins (2012) (0)
Abstracts of papers presented at the 1999 Meeting on Eukaryotic DNA Replication, September 15-September 19, 1999 (1997) (0)
Characterization of Protein Which Binds Specifically to a Putative Origin of Cellular DNA-Replication (1986) (0)
ARS Binding Factors from Saccharomyces cerevisiae (1992) (0)
Abstracts of papers presented at the 1995 Meeting on Eukaryotic DNA Replication, September 6-September 10, 1995 (1995) (0)
Decision letter: CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold (2020) (0)
DNA-Replication in Human and Yeast-Cells (1992) (0)
Regulation of the Eukaryotic Cell-Cycle - Final Discussion (1992) (0)
Nuclear Organization & Function (2010) (0)
Left End Proteins of Adenoviruses (1980) (0)
The Ribosome: Cold Spring Harbor Symposia on Quantitative Biology, Volume LXVI (2002) (0)
Abstracts of papers presented at the 1989 Meeting on Eukaryotic DNA Replication, August 30-September 3, 1989 (1989) (0)
Biotechnology on Long Island (2002) (0)
Initiation of DNA replication (2009) (0)
The Interaction of Proteins and DNA Sequences Required for Adenovirus DNA Replication in-Vitro (1983) (0)
Joseph F. Sambrook (1939–2019) (2019) (0)
Joseph F. Sambrook (1939–2019) (2019) (0)
Author response: Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription (2016) (0)
Decision letter: Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation (2021) (0)
ORC, a replication initiator protein required for multiple aspects of cell division cycle (2002) (0)
Author response: Structure of the active form of human origin recognition complex and its ATPase motor module (2016) (0)
temporally specific fashion in vivo. stable replication forks assembled in a Nuclear DNA synthesis in vitro is mediated via (2013) (0)
RoleoftheAdenovirus EBB19,000-Dalton TumorAntigen inRegulating EarlyGeneExpression (1988) (0)
Decision letter: A helicase-tethered ORC flip enables bidirectional helicase loading (2021) (0)
Decision letter: The role of Rif1 in telomere length regulation is separable from its role in origin firing (2020) (0)
NOTES TheDNA-Binding DomainofSimian Virus40TumorAntigen HasMultiple Functions (1993) (0)
Decision letter: Cdc7 activates replication checkpoint by phosphorylating the Chk1-binding domain of Claspin in human cells (2019) (0)
Origin Binding Proteins from Yeast (1989) (0)
Identification and characterization of ORC-interacting protein: Yph1p in Saccharomyces cerevisiae (2001) (0)
Human mitochondrial genome can replicate in the Yarrowia lipolytica yeast (2016) (0)
Decision letter: Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53 (2020) (0)
Decision letter: Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones (2020) (0)
Drosophila factors in vitro. T-antigen-dependent DNA replication with Simian virus 40 origin- and (2013) (0)
Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance (2013) (0)
Analysis ofa Protein-Binding Domainofp53 (1993) (0)
Chromosomes and expression mechanisms: Editorial overview (1994) (0)
Molecular genetics of cancer (1994) (0)
Atomic model of mutant Mcm2-7 hexamer with Mcm6 WHD truncation (2020) (0)
Two lives in science: the scientist-administrator (1996) (0)
Investigation of the Causes of Breast Cancer at the Cellular Level: Isolation of In Vivo Binding Sites of the Human Origin Recognition Complex (2002) (0)
Cold Spring Harbor Symposia on Quantitative Biology - Foreword (1991) (0)
The Cell Surface - Foreword (1992) (0)
The ribosome : proceedings of 2001 symposium (2016) (0)
Abstracts of papers presented at the 1993 Meeting on Eukaryotic DNA Replication, September 8-September 12, 1993 (1993) (0)
The cell cycle : abstracts of papers presented at the LVI Cold Spring Harbor Symposium on Quantitative Biology, May 29-June 5, 1991 (1991) (0)
Decision letter: Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 (2019) (0)
Biochemical studies on replication of the genome in eukaryotes (27.1) (2014) (0)
DNA Replication in-Vitro from the Sv-40 Origin (1989) (0)
Mechanism and Regulation of DNA Replication Lessons from Sv-40 (1991) (0)
Decision letter: The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions (2021) (0)
Crystal structure of a Orc1p-Sir1p complex (2005) (0)
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) (2020) (0)
Symposia (2016) (0)
Crystal structure of the N-terminal BAH domain of Orc1p (2002) (0)
Correction for Yuan et al., Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 (2021) (0)
A role for a nuclear envelope localized adenovirus tumor antigen in virus mediated transformation and lytic infection (1985) (0)
Abstracts of papers presented at the LXIV Cold Spring Harbor Symposium on Quantitative Biology, June 2-June 7, 1999 : signaling & gene expression in the immune system (1999) (0)
Key mechanism in the loading and activation of the replicative helicase MCM2-7 (2016) (0)
Molecular genetics of cancer : abstracts of papers presented at the LIX Cold Spring Harbor Laboratory Symposium on Quantitative Biology, June 1-June 8, 1994 (1994) (0)
Decision letter: Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins (2019) (0)
Cloning, Expression, andChromosomal Localization ofthe 140-Kilodalton Subunit ofReplication Factor C fromMiceandHumans (1994) (0)
Decision letter: The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes (2019) (0)
Initiation of Virus and Cell-DNA Replication (1993) (0)
Meier-Gorlin Syndrome (2016) (0)
Abstracts of papers presented at the 2001 Meeting on Eukaryotic DNA Replication, September 5-September 9, 2001 (2001) (0)
Mechanism and Control of Cellular DNA Replication (1993) (0)
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) (2020) (0)
ATP-dependent Assembly of the Human Origin (2007) (0)
Regulation of Adenovirus Early Gene-Expression by the E1b 19k Tumor-Antigen (1987) (0)
Ars Binding Factors in DNA Replication and Transcriptional Silencing (1990) (0)
Independent Mutations in Adenovirus Type 2 Ts-111 Cause Degradation of Cellular DNA and Defective Viral DNA Replication (1984) (0)
The Biology of Plants. Foreword. (2012) (0)
Cloning, Expression, and Chromosomal Localization of the 140-Kilodalton Subunit of Replication (0)
Editor's evaluation: A helicase-tethered ORC flip enables bidirectional helicase loading (2021) (0)
Structure and function studies of replication initiation factors (2016) (0)
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution (2020) (0)

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