Brunangelo Falini
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Brunangelo Falini's Degrees
- PhD Physics University of Milan
- Masters Mathematics University of Bologna
Why Is Brunangelo Falini Influential?
(Suggest an Edit or Addition)According to Wikipedia, Brunangelo Falini is an Italian hematologist, academic and researcher. He is a Full Professor of Hematology, and Head of the Institute of Hematology and Bone Marrow Transplantation at University of Perugia.
Brunangelo Falini's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. (1994) (6264)
- Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. (2004) (3681)
- Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). (1984) (3311)
- The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. (1985) (1836)
- Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. (2005) (1748)
- Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. (2011) (999)
- CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features. (2000) (841)
- Nucleophosmin and cancer (2006) (807)
- BRAF mutations in hairy-cell leukemia. (2011) (763)
- Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. (2005) (750)
- Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients (2007) (590)
- Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases (2002) (586)
- BCL-6 protein is expressed in germinal-center B cells. (1995) (585)
- ALK+ lymphoma: clinico-pathological findings and outcome. (1999) (572)
- Nucleophosmin regulates the stability and transcriptional activity of p53 (2002) (541)
- Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin (2008) (529)
- Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features. (2007) (526)
- A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. (2000) (462)
- CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. (1995) (448)
- Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma. (2003) (401)
- Diagnosis of human lymphoma with monoclonal antileukocyte antibodies. (1983) (370)
- Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma. (2015) (350)
- HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse. (2014) (343)
- Marker expression in peripheral T-cell lymphoma: a proposed clinical-pathologic prognostic score. (2006) (343)
- Antigen retrieval techniques in immunohistochemistry: comparison of different methods (1997) (340)
- Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study (2020) (339)
- Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis (2008) (326)
- Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML. (2009) (321)
- EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. (2009) (320)
- Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance. (2005) (319)
- BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope. (1989) (312)
- PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule. (1993) (309)
- Origin of nodular lymphocyte-predominant Hodgkin's disease from a clonal expansion of highly mutated germinal-center B cells. (1997) (299)
- Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations (2006) (288)
- TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations. (1999) (274)
- Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. (2006) (273)
- Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription. (2001) (272)
- ALK expression defines a distinct group of T/null lymphomas ("ALK lymphomas") with a wide morphological spectrum. (1998) (267)
- The acute promyelocytic leukaemia-associated PML gene is induced by interferon. (1995) (259)
- Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia. (2015) (241)
- Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype. (2011) (232)
- Peripheral T-cell lymphoma associated with hemophagocytic syndrome. (1990) (230)
- Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity? (2011) (224)
- Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia. (1999) (218)
- Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin (1992) (218)
- Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications (2009) (217)
- Nucleophosmin Is Required for DNA Integrity and p19Arf Protein Stability (2005) (217)
- Hodgkin's lymphoma: the pathologist's viewpoint. (2002) (214)
- Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues. (1989) (210)
- Lymphomas expressing ALK fusion protein(s) other than NPM-ALK. (1999) (209)
- Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1) (2004) (209)
- Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry. (2002) (204)
- Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias. (2007) (200)
- Gene Expression Profiling of Hairy Cell Leukemia Reveals a Phenotype Related to Memory B Cells with Altered Expression of Chemokine and Adhesion Receptors (2004) (191)
- Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype. (2005) (184)
- Analysis of MUM1/IRF4 Protein Expression Using Tissue Microarrays and Immunohistochemistry (2001) (181)
- Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1. (1992) (180)
- Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia. (2006) (179)
- A revised European-American classification of lymphoid neoplasms proposed by the International Lymphoma Study Group. A summary version. (1995) (179)
- Lymphohistiocytic T‐cell lymphoma (anaplastic large cell lymphoma CD30+/Ki‐1 + with a high content of reactive histiocytes) (1990) (176)
- AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features. (2009) (170)
- Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation. (2012) (168)
- Induction chemotherapy strategies for primary mediastinal large B-cell lymphoma with sclerosis: a retrospective multinational study on 426 previously untreated patients. (2002) (168)
- Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia. (2017) (167)
- Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin (2005) (167)
- Randomized trial with or without granulocyte colony-stimulating factor as adjunct to induction VNCOP-B treatment of elderly high-grade non-Hodgkin's lymphoma. (1997) (166)
- The International Consensus Classification of Mature Lymphoid Neoplasms: A Report from the Clinical Advisory Committee. (2022) (165)
- Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies. (1986) (164)
- Nodular lymphocyte predominance Hodgkin's disease. A distinct clinicopathological entity. (1994) (159)
- Elderly aggressive-histology non-Hodgkin's lymphoma: first-line VNCOP-B regimen experience on 350 patients. (1999) (157)
- A new variant anaplastic lymphoma kinase (ALK)-fusion protein (ATIC-ALK) in a case of ALK-positive anaplastic large cell lymphoma. (2000) (156)
- Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins. (2003) (153)
- Anaplastic large cell lymphoma: pathological, molecular and clinical features (2001) (150)
- Differential expression of BCL-6, CD138/syndecan-1, and Epstein-Barr virus-encoded latent membrane protein-1 identifies distinct histogenetic subsets of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. (1998) (148)
- Mutant NPM1 Maintains the Leukemic State through HOX Expression. (2018) (147)
- Double Immunoenzymatic Labelling (1983) (145)
- Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin. (2002) (141)
- Fludarabine plus mitoxantrone with and without rituximab versus CHOP with and without rituximab as front-line treatment for patients with follicular lymphoma. (2004) (140)
- Expression status of BCL-6 and syndecan-1 identifies distinct histogenetic subtypes of Hodgkin's disease. (1998) (140)
- Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma. (2012) (138)
- Peripheral T-cell lymphomas. Clinico-pathologic study of 168 cases diagnosed according to the R.E.A.L. Classification. (1997) (136)
- Detection of normal and chimeric nucleophosmin in human cells. (1999) (136)
- Early autologous stem-cell transplantation versus conventional chemotherapy as front-line therapy in high-risk, aggressive non-Hodgkin's lymphoma: an Italian multicenter randomized trial. (2003) (133)
- Immunocytochemical diagnosis of acute promyelocytic leukemia (M3) with the monoclonal antibody PG-M3 (anti-PML). (1997) (131)
- Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma (2009) (131)
- Cytoplasmic mutated nucleophosmin (NPM) defines the molecular status of a significant fraction of myeloid sarcomas (2007) (130)
- Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma. (2018) (130)
- Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia (2005) (128)
- The genetics of nodal marginal zone lymphoma. (2016) (125)
- Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells. (2015) (125)
- Distinctive expression pattern of the BCL-6 protein in nodular lymphocyte predominance Hodgkin's disease. (1996) (123)
- Genotypic analysis of large cell lymphomas which express the Ki‐1 antigen (1987) (122)
- Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT). (2003) (118)
- Essential mixed cryoglobulinemia, type II: a manifestation of a low-grade malignant lymphoma? Clinical-morphological study of 12 cases with special reference to immunohistochemical findings in liver frozen sections. (1988) (115)
- Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma. (2000) (114)
- Analysis of the distribution of human CD38 and of its ligand CD31 in normal tissues. (1998) (113)
- Co‐expression of CD79a (JCB117) and CD3 by lymphoblastic lymphoma (1998) (110)
- Monoclonal antibodies PG-B6a and PG-B6p recognize, respectively, a highly conserved and a formol-resistant epitope on the human BCL-6 protein amino-terminal region. (1996) (107)
- CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice. (2010) (106)
- Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1). (2010) (106)
- Immunohistochemical detection of the multidrug transport protein P1 70 in human normal tissues and malignant lymphomas (1991) (106)
- Expression of lymphoid‐associated antigens on Hodgkin's and Reed‐Sternberg cells of Hodgkin's disease. An immunocytochemical study on lymph node cytospins using monoclonal antibodies (1987) (105)
- ALK expression in extranodal anaplastic large cell lymphoma favours systemic disease with (primary) nodal involvement and a good prognosis and occurs before dissemination (2000) (104)
- Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants. (2007) (102)
- Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity. (2002) (100)
- Anaplastic large-cell lymphoma: clinical and prognostic evaluation of 90 adult patients. (1996) (100)
- Mutational landscape of AML with normal cytogenetics: biological and clinical implications. (2013) (98)
- The cryptic inv(2)(p23q35) defines a new molecular genetic subtype of ALK-positive anaplastic large-cell lymphoma. (1998) (97)
- Lymphotoxin, tumour necrosis factor and interleukin‐6 gene transcripts are present in Hodgkin and Reed‐Sternberg cells of most Hodgkin's disease cases (1993) (96)
- Evolving concepts in the pathogenesis of hairy-cell leukaemia (2006) (95)
- Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma. (1995) (93)
- NPM1-mutated acute myeloid leukemia: from bench to bedside. (2020) (93)
- Myeloperoxidase expression by histiocytes in Kikuchi's and Kikuchi-like lymphadenopathy. (2001) (92)
- Induction of apoptosis by ribosome‐inactivating proteins and related immunotoxins (1996) (92)
- Diffuse large B‐cell lymphoma: one or more entities? Present controversies and possible tools for its subclassification (2002) (90)
- Hairy cell leukemia. Diagnosis of bone marrow involvement in paraffin-embedded sections with monoclonal antibody DBA.44. (1992) (89)
- IRTA1 is selectively expressed in nodal and extranodal marginal zone lymphomas (2012) (88)
- A proposal for classification of lymphoid neoplasms (by the International Lymphoma Study Group) (1994) (88)
- Nucleophosmin mutations in acute myeloid leukemia: A tale of protein unfolding and mislocalization (2013) (87)
- Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts. (2016) (86)
- High levels of the soluble form of CD30 molecule in rheumatoid arthritis (RA) are expression of CD30+ T cell involvement in the inflamed joints (1995) (86)
- Evidence for monoclonal T lymphocyte proliferation in angioimmunoblastic lymphadenopathy. (1986) (86)
- Human immunodeficiency virus-associated Hodgkin's disease derives from post-germinal center B cells. (1999) (85)
- Ber‐H2 (anti‐CD30)‐saporin immunotoxin: a new tool for the the treatment of Hodgkin's disease and CD30+ lymphoma: in vitro evaluation (1992) (84)
- NPM1 mutations and cytoplasmic nucleophosmin are mutually exclusive of recurrent genetic abnormalities: a comparative analysis of 2562 patients with acute myeloid leukemia (2008) (83)
- Heterogeneous nuclear expression of the promyelocytic leukemia (PML) protein in normal and neoplastic human tissues. (1996) (83)
- Variable expression of leucocyte-common (CD45) antigen in CD30 (Ki1)-positive anaplastic large-cell lymphoma: implications for the differential diagnosis between lymphoid and nonlymphoid malignancies. (1990) (82)
- IL-17-producing CD4−CD8− T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjögren's syndrome (2012) (82)
- Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA (2013) (81)
- Expression of bcl-6 and CD10 in Primary Mediastinal Large B-Cell Lymphoma: Evidence for Derivation From Germinal Center B Cells? (2001) (81)
- Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification. (2006) (81)
- CD30+ T Cells in Rheumatoid Synovitis: Mechanisms of Recruitment and Functional Role (2000) (81)
- Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. (2010) (80)
- A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice (2013) (80)
- Aberrant somatic hypermutation in tumor cells of nodular-lymphocyte-predominant and classic Hodgkin lymphoma. (2006) (79)
- Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation (1996) (79)
- Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives (2009) (79)
- Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates (2018) (78)
- BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity. (2015) (78)
- Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy? (2011) (78)
- BRAF V600E mutation in hairy cell leukemia: from bench to bedside. (2016) (78)
- High CD33 expression levels in acute myeloid leukemia cells carrying the nucleophosmin (NPM1) mutation (2011) (75)
- "Designed" grafts for HLA-haploidentical stem cell transplantation. (2014) (75)
- Genomic instability and recurrent breakpoints are main cytogenetic findings in Hodgkin's disease. (1999) (74)
- PAX5 Expression in Acute Leukemias (2004) (72)
- Identification of outcome predictors in diffuse large B-cell lymphoma. Immunohistochemical profiling of homogeneously treated de novo tumors with nodal presentation on tissue micro-arrays. (2005) (72)
- Frequent expression of the NPM-ALK chimeric fusion protein in anaplastic large-cell lymphoma, lympho-histiocytic type. (1997) (71)
- Gene expression analysis provides a potential rationale for revising the histological grading of follicular lymphomas (2008) (71)
- Bcl-6 protein expression in normal and neoplastic lymphoid tissues. (1997) (71)
- Immunophenotypic and Genotypic Markers of Follicular Center Cell Neoplasia in Diffuse Large B-Cell Lymphomas (2000) (70)
- Immunohistological analysis of human bone marrow trephine biopsies using monoclonal antibodies (1984) (70)
- BCL-6 protein expression in AIDS-related non-Hodgkin's lymphomas: inverse relationship with Epstein-Barr virus-encoded latent membrane protein-1 expression. (1997) (69)
- Germline NPM1 mutations lead to altered rRNA 2’-O-methylation and cause dyskeratosis congenita (2019) (68)
- Primary mediastinal large B-cell lymphoma with sclerosis: a clinical study of 89 patients treated with MACOP-B chemotherapy and radiation therapy. (2001) (66)
- A new monoclonal antibody (KB61) recognizing a novel antigen which is selectively expressed on a subpopulation of human B lymphocytes. (1986) (66)
- Primary follicular lymphoma of the testis in childhood: an entity with peculiar clinical and molecular characteristics (2002) (65)
- Frequent expression of IL-7 gene transcripts in tumor cells of classical Hodgkin's disease. (1995) (65)
- Cuplike nuclei (prominent nuclear invaginations) in acute myeloid leukemia are highly associated with FLT3 internal tandem duplication and NPM1 mutation (2009) (64)
- A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin, and ARF (2009) (64)
- Peripheral T cell lymphoma, not otherwise specified: the stuff of genes, dreams and therapies (2008) (64)
- Evolutionary conservation in various mammalian species of the human proliferation-associated epitope recognized by the Ki-67 monoclonal antibody. (1989) (63)
- A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study (2016) (63)
- Defective recruitment and activation of ZAP‐70 in common variable immunodeficiency patients with T cell defects (2000) (62)
- Mediastinal large B‐cell lymphoma: clinical and immunohistological findings in 18 patients treated with different third‐generation regimens (1995) (62)
- Constant activation of the RAF-MEK-ERK pathway as a diagnostic and therapeutic target in hairy cell leukemia (2013) (62)
- First Report of the Gimema LAL1811 Phase II Prospective Study of the Combination of Steroids with Ponatinib As Frontline Therapy of Elderly or Unfit Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (2017) (61)
- Biochemical detection of novel anaplastic lymphoma kinase proteins in tissue sections of anaplastic large cell lymphoma. (1999) (61)
- CD 30 1 anaplastic large cell lymphoma : a review of its histopathologic , genetic , and clinical features (2000) (60)
- Histological and immunohistological analysis of human lymphomas. (1989) (59)
- Identification and functional characterization of a cytoplasmic nucleophosmin leukaemic mutant generated by a novel exon-11 NPM1 mutation (2007) (59)
- Lymphoma classification proposal: clarification. (1995) (57)
- Bone marrow findings further support the hypothesis that essential mixed cryoglobulinemia type II is characterized by a monoclonal B-cell proliferation. (1995) (57)
- Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia. (2006) (57)
- In vivo targeting of Hodgkin and Reed‐Sternberg cells of Hodgkin's disease with monoclonal antibody Ber‐H2 (CD30): immimohistological evidence (1992) (56)
- Gene rearrangements in T‐cell lymphoblastic lymphoma (1999) (55)
- Value of monoclonal anti-CD22 (p135) antibodies for the detection of normal and neoplastic B lymphoid cells (1987) (53)
- Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia. (2015) (52)
- Histiocytic necrotizing lymphadenitis without granulocytic infiltration (Kikuchi's lymphadenitis). Morphological and immunohistochemical study of eight cases (1987) (52)
- Nucleophosmin C-terminal Leukemia-associated Domain Interacts with G-rich Quadruplex Forming DNA* (2010) (51)
- Description of a sequential staining procedure for double immunoenzymatic staining of pairs of antigens using monoclonal antibodies. (1986) (51)
- Acute myeloid leukemia with mutated nucleophosmin ( NPM 1 ) : is it a distinct entity ? (2011) (51)
- Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy (2009) (51)
- Anaplastic large cell lymphoma: update of findings. (1995) (50)
- Comparison between the monoclonal antibodies Ki‐67 and PC 10 in 125 malignant lymphomas (1993) (50)
- The differential diagnosis of hairy cell leukemia with a panel of monoclonal antibodies. (1985) (50)
- Pathobiology of Primary Mediastinal B-Cell Lymphoma (2003) (50)
- Anti‐CD30 (BER‐H2) immunotoxins containing the type‐1 ribosome‐inactivating proteins momordin and PAP‐S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice (1996) (50)
- Acute leukaemia immunophenotyping in bone‐marrow routine sections (1999) (49)
- Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca(2+)-dependent association with annexin VI. (2005) (49)
- Genomics of Hairy Cell Leukemia (2017) (49)
- In human genome, generation of a nuclear export signal through duplication appears unique to nucleophosmin (NPM1) mutations and is restricted to AML (2008) (48)
- Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target (2018) (48)
- The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutations (2012) (48)
- Local Expansion of Allergen-Specific CD30+Th2-Type γδ T Cells in Bronchial Asthma (1995) (47)
- Anaplastic large cell lymphoma Hodgkin's-like: a randomized trial of ABVD versus MACOP-B with and without radiation therapy. (1998) (47)
- Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation. (2011) (47)
- Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice (2008) (46)
- Ber-ACT8: new monoclonal antibody to the mucosa lymphocyte antigen. (1991) (46)
- Immunocytochemical evaluation of the percentage of proliferating cells in pathological bone marrow and peripheral blood samples with the Ki‐67 and anti‐bromo‐deoxyuridine monoclonal antibodies (1988) (46)
- BCL-6 Protein Expression in Human Peripheral T-Cell Neoplasms Is Restricted to CD30+ Anaplastic Large-Cell Lymphomas (1997) (44)
- Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin (2014) (43)
- The pathologist's view point. Part I--indolent lymphomas. (2000) (43)
- Vemurafenib plus Rituximab in Refractory or Relapsed Hairy-Cell Leukemia. (2021) (43)
- Mantle cell lymphoma (2009) (43)
- Erythrophagocytosis by undifferentiated lung carcinoma cells (1980) (42)
- Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics (2015) (40)
- Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): A comparison with NPMc+ AML (2006) (40)
- High-Risk Clonal Hematopoiesis as the Origin of AITL and NPM1-Mutated AML. (2018) (40)
- A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation (2014) (40)
- CD30+ anaplastic large‐cell lymphoma, null type, with signet‐ring appearance (1997) (40)
- The corepressors BCOR and BCORL1: two novel players in acute myeloid leukemia (2012) (40)
- New classification of acute myeloid leukemia and precursor-related neoplasms: changes and unsolved issues. (2010) (39)
- T regulatory cell separation for clinical application. (2012) (38)
- Histology and immunohistology of bone marrow biopsy in multiple myeloma (1989) (38)
- Evaluation of immunotoxins containing single‐chain ribosome‐inactivating proteins and an anti‐CD22 monoclonal antibody (OM124): in vitro and in vivo studies (1998) (38)
- Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications (2014) (37)
- SAVI: a statistical algorithm for variant frequency identification (2013) (36)
- T-bet-positive and IRTA1-positive monocytoid B cells differ from marginal zone B cells and epithelial-associated B cells in their antigen profile and topographical distribution. (2005) (36)
- Aberrant cytoplasmic expression of C-terminal-truncated NPM leukaemic mutant is dictated by tryptophans loss and a new NES motif (2007) (36)
- Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease. (2004) (35)
- Granular Cell Tumor: An Immunohistochemical Study (1994) (35)
- Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia. (2006) (35)
- Late relapse of acute myeloid leukemia with mutated NPM1 after eight years: evidence of NPM1 mutation stability. (2009) (34)
- Detection of metastatic tumour cells in routine bone marrow smears by immuno‐alkaline phosphatase labelling with monoclonal antibodies (1985) (33)
- Folding mechanism of the C‐terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance (2009) (32)
- Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help (2010) (31)
- Cytoplasmic nucleophosmin is not detected in blastic plasmacytoid dendritic cell neoplasm (2009) (31)
- Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin (2017) (31)
- The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model. (2013) (31)
- Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas (2020) (30)
- A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen. (1986) (30)
- Characterization of a New Monoclonal Antibody Against PAX5/BASP in 1525 Paraffin-embedded Human and Animal Tissue Samples (2010) (30)
- T-lymphoblastic lymphomas expressing the non-disulfide-linked form of the T-cell receptor gamma/delta: characterization with monoclonal antibodies and genotypic analysis. (1989) (29)
- Nodal reactive and neoplastic proliferation of monocytoid and marginal zone B cells: an immunoarchitectural and molecular study highlighting the relevance of IRTA1 and T‐bet as positive markers (2013) (29)
- A western blot assay for detecting mutant nucleophosmin (NPM1) proteins in acute myeloid leukaemia (2008) (28)
- Single and Double Immunoenzymatic Techniques for Labeling Tissue Sections with Monoclonal Antibodies a (1983) (28)
- Monoclonal antibodies in diagnostic pathology: techniques and applications. (1983) (27)
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- Choroidal vasculature analysis in MEK inhibitor-associated retinopathy (2022) (1)
- Non-B, non-T acute lymphoblastic leukaemia terminating in malignant histiocytosis: a new case and a review of the literature. (1982) (1)
- The metalloproteinase inhibitor Prinomastat reduces AML growth, prevents stem cell loss and improves chemotherapy effectiveness (2020) (1)
- Getting away with phase transition: NPM1-mutated bone myeloid sarcoma mimicking Ewing sarcoma (2019) (1)
- Sideroblastic anemia assOCIATED WITH HAIRY CELL LEUKEMIA (1981) (1)
- Diffuse large B-cell lymphoma (DLBCL), anaplastic variant. report on a problematic case primarily arising in the stomach. (2002) (1)
- New Pathogenetic Insights Into Classical Hodgkin Lymphoma Revealed by Gene Expression Profiling of Microdissected Hodgkin/Reed-Sternberg Cells. (2009) (1)
- The immunohistological analysis of undecalcified human bone marrow trephine biopsies. Technical and diagnostic aspects. (1984) (1)
- How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation (2018) (1)
- , Alessia acute myeloid leukemia : impact on WHO classification Mutated nucleophosmin detects clonal multilineage involvement in (2006) (0)
- AML risk models: where do we stand ? (2022) (0)
- Light chain plasmacytoid lymphocytic lymphoma ANTONIOTABILIO M.D. (1981) (0)
- About 17% of AML with NPM1 mutations Show a Specific Pattern of Chromosome Aberrations but These Cases Do Not Differ Prognostically from AML with NPM1 Mutations Carrying a Normal Karyotype (2008) (0)
- Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation (2019) (0)
- A Curious Novel Combination of Nucleophosmin (NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML) (2021) (0)
- Subject Index Vol. 95, 1996 (1996) (0)
- Diffuse large B-cell lymphoma of the testis. (2022) (0)
- Marker Expression in Peripheral T-Cell Lymphoma Unspecified: Proposal of a Clinical-Pathologic Prognostic Score. (2005) (0)
- Acute Myeloid Leukemia with Mutated NPM1 Presenting with Life-Threatening, Either Arterial or Venous, Thromboembolism: a Report of 4 Cases. (2009) (0)
- David York Mason (1941-2008). Antibody wizard and a founder of modern hemopathology (2008) (0)
- Mutant NPM 1 Maintains th e Leukemic State through HOX Expression Graphical Abstract Highlights (2018) (0)
- A unique microRNA signature associated with nucleophosmin mutations in normal karyotype acute myeloid leukemia (2007) (0)
- The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy (2017) (0)
- and leukemia: clinical value of their detection by immunocytochemistry Proteins encoded by genes involved in chromosomal alterations in lymphoma (2010) (0)
- Denaturing high performance liquid chromatography analysis of npm1 mutations in adult primary acute myeloid leukemia. (2005) (0)
- CAR T cell‐driven cerebrospinal fluid cytokine storm with confounding neurological picture in chemorefractory primary cardiac lymphoma (2022) (0)
- IL3-zetakine combined with a CD33 costimulatory receptor as a Dual CAR approach for safer and selective targeting of AML. (2022) (0)
- [The Haemolymphopathology Italian Group (H.I.G.): an essential resource for the new technical and organization problems troubling modern haemolymphopathology diagnostics]. (2006) (0)
- Mutant NPM1: Nuclear export and the mechanism of leukemogenesis (2023) (0)
- AML-377 A "Designed" High-Throughput Drug Screening Strategy Identifies Aurora Kinase A Inhibitors as Promising Preclinical Candidates for the Treatment of NPM1-Mutated AML. (2022) (0)
- Gene expression analysis of peripheral T-cell lymphoma not otherwise specified reveals two distinct subgroups and recurrent PDGFRα deregulation (2006) (0)
- Gene expression analysis of peripheral T-cell lymphoma not otherwise specified reveals two distinct subgroups and recurrent PDGFR-alpha deregulation (2009) (0)
- The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein (2022) (0)
- [Aggressive lymphomas: a convenient concept or an anatomo-pathological reality?]. (2000) (0)
- Abstract LB044: Tracking clonal hematopoiesis in patients with classical Hodgkin lymphoma (2021) (0)
- [Rosette formation test with mouse erythrocytes in chronic lymphatic leukosis: correlation with other membrane receptors]. (1978) (0)
- [Cellular immunity in patients with Hodgkin's disease: modification induced by incubating lymphocytes with fetal calf serum and Hodgkin's serum]. (1979) (0)
- Dissecting the Hierarchical Level of Hematopoietic Progenitors9 Involvement in AML with NPM1 Gene Mutation and Their Engraftment Potential in Immunocompromised Mice. (2009) (0)
- Evaluation of proliferative pattern in human malignant lymphomas (1988) (0)
- 15. Anaplastic large cell lymphoma (2016) (0)
- Molecular studies on LAK cells. (1990) (0)
- [Immunohistochemical determination of glycoprotein P in 60 non-Hodgkin's lymphomas]. (1991) (0)
- Non-blastic meningeal leukemia during the myelofibrotic phase of chronic myeloid leukemia. (1981) (0)
- SARS‐CoV‐2 infection in patients with chronic lymphocytic leukemia: The Italian Hematology Alliance on COVID‐19 cohort (2022) (0)
- Function of Nucleophosmin in Zebrafish Hematopoiesis (2007) (0)
- Contents, Vol. 95, 1996 (1996) (0)
- Diffuse large B-cell lymphoma (DLBCL) of the waldeyer'ring (WR) frequently have a GC-like phenotype: a clinico-pathological study of 209 patients from the groupe d'étude des lymphomes de l'adulte (GELA). (2008) (0)
- AML-099 Prolonged XPO1 Inhibition Is Essential for Optimal Anti-Leukemic Activity in NPM1-Mutated AML. (2022) (0)
- Abstract 1031: Nuclear relocalization of NPM1c induces terminal differentiation and cell growth arrest (2017) (0)
- Histone Deacetylase Inhibitors Induce Cell Growth Inhibition and Apoptosis in NPM1-Mutated AML Cells: A Possible Role for Epigenetic Therapies in AML Carrying NPM1 Gene Mutations (2011) (0)
- Bcl-6 protein expression in nodular lymphocyte predominance Hodgkinʼs disease (nLPHD): further evidence supporting its histogenetic distinctiveness versus classic HD (1996) (0)
- Venetoclax in Relapsed or Refractory Hairy-Cell Leukemia. (2023) (0)
- 186 AZACITIDINE IS EFFICACIOUS IN CHRONIC MYELOMONOCYTIC LEUKEMIA INVOLVING SKIN AND MUCOSA (2015) (0)
- immunotherapy factor receptor superfamily as a tool for diagnosis and CD 30 ( Ki-1 ) molecule : a new cytokine receptor of the tumor necrosis (2000) (0)
- [Considerations in Hodgkin's disease]. (1993) (0)
- Generation of the first monoclonal antibody using mouse hybridomas (2022) (0)
- Running title: Tregs in haploidentical transplantation (2016) (0)
- Is histiocytic reticulosis an infectious disease? (1982) (0)
- The Detection of Multilineage Dysplasia (MLD) Has No Influence on Prognosis in NPM1 Mutated Acute Myeloid Leukemia (AML) with Normal Karyotype (2008) (0)
- Biological and therapeutic relevance of the BRAF-MEK-ERK pathway in hairy cell leukemia (2014) (0)
- A Distributed International Patient Data Registry for Hairy Cell Leukemia (2016) (0)
- T-cell adoptive immunotherapy prevents acute leukemia relapse HLA-haploidentical transplantation with regulatory and conventional (2014) (0)
- Reciprocal Interaction between NPM Leukemic Mutants and Arf: Structural Basis and Functional Consequences (2006) (0)
- Short Communication Biochemical Detection of Novel Anaplastic Lymphoma Kinase Proteins in Tissue Sections of Anaplastic Large Cell Lymphoma (1999) (0)
- Identification of a New Subclass of ALK Negative Anaplastic Large Cell Lymphoma Expressing Aberrant Levels of ERBB4 Transcripts (2014) (0)
- DHPLC analysis of NPM1 mutations in adult primary AML. (2006) (0)
- DOSE-DEPENDENT COMPETITION BETWEEN NPM LEUKEMIC MUTANTS AND ARF PROTEIN FOR SUBCELLULAR DISTRIBUTION: A NUCLEAR TUG-OF-WAR (2006) (0)
- The Presence of Multilineage Dysplasia (MLD) Has No Significant Impact On Biological, Clinico-Pathological, and Prognostic Features in AML with Mutated Nucleophosmin (NPM1). (2009) (0)
- PF227 PROGNOSTIC VALUE OF CLONAL HEMATOPOIESIS-MUTATIONS DETECTED AT DIAGNOSIS IN ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE (2019) (0)
- Fever and chloramphenicol in leukemic patients. (1980) (0)
- [Evaluation of the immunological status of patients with Hodgkin's disease]. (1978) (0)
- Promyelocytic Leukemia Genetic Diagnosis and Molecular Monitoring in the Management of Acute (2011) (0)
- Local Expansion of Allergen-Specific CD 30 + Th 2-Type y 6 T Cells in Bronchial Asthma (2007) (0)
- NPM1 AND FLT3-ITD MUTATIONS COOPERATE TO IMPAIR HEMATOPOIETIC STEM/PROGENITOR CELLS DIFFERENTIATION AND DEREGULATE GATA1 IN A MOUSE MODEL OF AML (2014) (0)
- NPM1 gene mutations in acute myeloid leukemia. (2005) (0)
- Acute myeloid leukemia risk models: Where do we stand? (2022) (0)
- New mechanism of lymphoma-induced bone marrow aplasia (2016) (0)
- Abstract A27: Long noncoding RNA expression in cytogenetically normal acute myeloid leukemia identifies a distinct signature associated with NPM1 mutations (2016) (0)
- Quantitative Detection of NPM1 Mutations as Marker of Minimal Residual Disease (MRD) in the Large Majority of AML with Normal Karyotype. (2005) (0)
- NPM1 AND FLT3-ITD MUTATIONS SINERGISTICALLY INDUCE GATA1 EPIGENETIC SILENCING IN A AML MOUSE MODEL (2016) (0)
- and IL-6) and are activated and stimulated to grow by IL-1 granulocyte-monocyte-CSF, macrophage- CSF, interleukin-1 (IL-1), (granulocyte colony-stimulating factor (CSF), Human peritoneal mesothelial cells produce many cytokines (2012) (0)
- MOLECULAR PROLIFE BY NEXT GENERATION SEQUENCING OF ACUTE MYELOID LEUKEMIA WITH NORMAL KARYOTYPE: CLINICAL RESULTS FROM THE PROSPECTIVE TRIAL 02/06 OF THE NORTHERN ITALY LEUKEMIA GROUP (NILG) (2018) (0)
- SARS‐CoV‐2 infection and vaccination in patients with hairy‐cell leukaemia (2022) (0)
- Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia (2007) (0)
- How do we define Hodgkin’s disease? The authors’ reply (2003) (0)
- Mechanism of Altered Nucleo-Cytoplasmic Traffic of Nucleophosmin in Acute Myelogenous Leukemia Carrying Exon-12 NPM Mutations (NPMc+ AML). (2005) (0)
- How I treat refractory/relapsed diffuse large B‐cell lymphomas with CD19‐directed chimeric antigen receptor T cells (2023) (0)
- The Reed-Sternberg Cell and the CD30 Antigen (1995) (0)
- lymphocyte-predominant and classical Hodgkin's lymphoma Aberrant somatic hypermutation in tumor cells of nodular (2013) (0)
- Genomic landscape of virus-associated cancers (2023) (0)
- LYMPHOID NEOPLASIA Identi fi cation of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts (2015) (0)
- Tuned IL3-Zetakine Coupled to a CD33 Costimulatory Receptor As a Dual CAR for Safer and Selective Targeting of Acute Myeloid Leukemia (2022) (0)
- Homing and survival of thymidine kinase transduced T-limphocytes into NOD/SCID mice. (2001) (0)
- Gene Expression Analysis of Follicular Lymphoma Provides a Potential Rationale for Histological Grading Revision. (2007) (0)
- resistant epitope BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol- (2011) (0)
- Acknowledgement to Referees (2005) (0)
- TPD52: A novel B cell/plasma cell protein characterized by unique expression pattern and Ca+2-dependent association with annexin VI (2005) (0)
- TRACKING CLONAL HEMATOPOIESIS IN PATIENTS WITH CLASSICAL HODGKIN'S LYMPHOMA (2021) (0)
- Mlecular Monitoring of Acute Myeloid Leukemia Patients Carrying Nucleophosmin ( NPM1 ) Mutations Undergoing An Autologous Peripheral Blood Stem Cell Transplantation (2008) (0)
- WESTERN BLOT IDENTIFICATION OF NPM1 LEUKEMIC MUTANTS IN CYTOLOGICAL AML SAMPLES: A POWERFUL DIAGNOSTIC TECHNIQUE (2007) (0)
- Response: NPM1-mutated AML is an entity irrespective of whether or not chromosomal aberrations are present (2009) (0)
- Health Risks of Accidents at Nuclear Power Plants (2011) (0)
- Exon-12 nucleophosmin (NPM) mutation and aberrant cytoplasmic expression of NPM protein in leukemia cell line OCI-AML3 (2005) (0)
- One-Mutation Model Can Explain Age Incidence in AML Carrying Nucleophosmin (NPM1) Mutations. (2007) (0)
- IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY (2015) (0)
- Clonal Hematopoiesis Leading to AITL and NPM1-Mutated AML. (2018) (0)
- De-Regulation of MicroRNA Expression Is Detected in Hairy Cell Leukemia. (2009) (0)
- Gene expression analysis of peripheral T-cell lymphoma not otherwise specified reveals the existance of two subgroups related to different cellular counterparts. (2005) (0)
- Abstract 2872: Cytoplasmic localization of PU.1 with mutated NPM1 causes myeloid differentiation arrest (2016) (0)
- The NPM1 mutant defines AML irrespective of blast count. (2023) (0)
- THE BRAF-MEK-ERK PATHWAY IN HAIRY CELL LEUKEMIA: A COMPREHENSIVE DISSECTION IN PRIMARY LEUKEMIC CELLS OF ITS BIOLOGICAL AND THERAPEUTIC RELEVANCE (2014) (0)
- Myeloid Sarcoma (2019) (0)
- Bladder cancer and aploidentical bone marrow transplant with immunotherapy: Which is the relationship? (2019) (0)
- Anaplastic Large Cell Lymphoma : A Critical Reappraisal (2004) (0)
- Editor's/Publisher's Disclaimer (1998) (0)
- EARLY METABOLIC RESPONSE IN FOLLICULAR LYMPHOMA: A SUBSET ANALYSIS OF THE FOLL12 TRIAL BY THE FONDAZIONE ITALIANA LINFOMI (FIL) (2021) (0)
- Light chain plasmacytoid lymphocytic lymphoma (1981) (0)
- ‘Reply to Pitiot et al.’ (2007) (0)
- The gene mutation landscape of acute myeloid leukemia cell lines and its exemplar use to study the BCOR tumor suppressor (2023) (0)
- B-cell prolymphocytic leukemia after COVID-19 infection (2023) (0)
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