Bryan M. Turner
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British geneticist
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Why Is Bryan M. Turner Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bryan M. Turner is Professor of Experimental Genetics at School of Cancer Sciences, Institute of Biomedical Research, University of Birmingham in Birmingham, UK. He was educated at University College London, where he earned his BSc in Biochemistry and PhD in Human Biochemical Genetics . Before moving to Birmingham University in 1981, he was at the National Institute for Medical Research in Mill Hill and the Mt Sinai School of Medicine in New York .
Bryan M. Turner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex (1998) (3466)
- Histone acetylation and an epigenetic code. (2000) (1250)
- Cellular Memory and the Histone Code (2002) (1153)
- MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex (1999) (957)
- The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. (2004) (854)
- The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression (1993) (724)
- HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. (1996) (639)
- Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei (1992) (567)
- Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3 (1998) (439)
- Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern (1996) (386)
- Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes* (1999) (386)
- Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres (1997) (384)
- Defining an epigenetic code (2007) (377)
- Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors (2005) (371)
- Decoding the nucleosome (1993) (346)
- Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase (1998) (339)
- Crosstalk between CARM1 Methylation and CBP Acetylation on Histone H3 (2002) (309)
- Nuclear organization of mammalian genomes : Polar chromosome territories build up functionally distinct higher order compartments (1999) (308)
- Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila. (1994) (307)
- Histone acetylation and control of gene expression. (1991) (305)
- Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. (2006) (300)
- A unified phylogeny-based nomenclature for histone variants (2012) (292)
- Stress-induced transcription of satellite III repeats (2004) (283)
- Reading signals on the nucleosome with a new nomenclature for modified histones (2005) (274)
- Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations (2006) (272)
- X-Inactivation and histone H4 acetylation in embryonic stem cells. (1996) (260)
- Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation‐dependent but transcription‐independent manner. (1995) (256)
- General transcription factors bind promoters repressed by Polycomb group proteins (2001) (245)
- Immunoprecipitation of native chromatin: NChIP. (2003) (235)
- Histone acetylation as an epigenetic determinant of long-term transcriptional competence (1998) (210)
- Duplication and Maintenance of Heterochromatin Domains (1999) (196)
- Epigenetic responses to environmental change and their evolutionary implications (2009) (195)
- Histone H4 Acetylation of Euchromatin and Heterochromatin Is Cell Cycle Dependent and Correlated with Replication Rather Than with Transcription (2000) (174)
- Histone modifications in Arabidopsis- high methylation of H3 lysine 9 is dispensable for constitutive heterochromatin. (2003) (162)
- Histone acetylation in chromatin and chromosomes. (1995) (160)
- Dosage Compensation in the Mouse Balances Up-Regulation and Silencing of X-Linked Genes (2007) (158)
- Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis. (1999) (158)
- DNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1 (2001) (153)
- An increasingly complex code. (2002) (148)
- Vestiges of a DNA methylation system in Drosophila melanogaster? (1999) (141)
- Cross-talk between Histone Modifications in Response to Histone Deacetylase Inhibitors (2007) (140)
- Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells (2004) (139)
- Temporally restricted spatial localization of acetylated isoforms of histone H4 and RNA polymerase II in the 2-cell mouse embryo. (1995) (129)
- Human Class I Histone Deacetylase Complexes Show Enhanced Catalytic Activity in the Presence of ATP and Co-immunoprecipitate with the ATP-dependent Chaperone Protein Hsp70* (2002) (116)
- Histone deacetylases: complex transducers of nuclear signals. (1999) (113)
- Chromatin Remodeling at the Ig Loci Prior to V(D)J Recombination1 (2001) (111)
- Histone H4 acetylation in Drosophila Frequency of acetylation at different sites defined by immunolabelling with site‐specific antibodies (1991) (103)
- Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2‐H19 domain (2001) (100)
- Molecular and cytogenetic analysis of the spreading of X inactivation in X;autosome translocations. (2002) (99)
- Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function (2012) (96)
- Altered Nuclear Receptor Corepressor Expression Attenuates Vitamin D Receptor Signaling in Breast Cancer Cells (2006) (89)
- Stage‐dependent redistributions of acetylated histones in nuclei of the early preimplantation mouse embryo (1997) (89)
- The age related loss of activity of four enzymes in the human erythrocyte. (1974) (87)
- Deacetylase Activity Associates with Topoisomerase II and Is Necessary for Etoposide-induced Apoptosis* (2001) (87)
- Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes (1992) (85)
- Distinctive patterns of histone H4 acetylation are associated with defined sequence elements within both heterochromatic and euchromatic regions of the human genome. (1998) (83)
- Polymorphism of human alpha fucosidase. (1975) (82)
- Histone underacetylation is an ancient component of mammalian X chromosome inactivation. (1997) (81)
- Dosage compensation in mammals. (2015) (80)
- Identification of a conserved erythroid specific domain of histone acetylation across the α-globin gene cluster (2001) (77)
- A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation (1999) (76)
- Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis (2011) (76)
- The adjustable nucleosome: an epigenetic signaling module. (2012) (76)
- Histone H4 acetylation in human cells Frequency of acetylation at different sites defined by immunolabeling with site‐specific antibodies (1989) (75)
- Immunoprecipitation of chromatin. (1996) (73)
- Histone acetylation and X inactivation. (1998) (73)
- Preparation of site-specific antibodies to acetylated histones. (1999) (73)
- Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success (2016) (72)
- dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster. (2001) (71)
- Identification of protein antigens associated with the nuclear matrix and with clusters of interchromatin granules in both interphase and mitotic cells. (1987) (70)
- Immunostaining of modified histones defines high-level features of the human metaphase epigenome (2010) (69)
- Selective use of H4 acetylation sites in the yeast Saccharomyces cerevisiae. (1993) (68)
- Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells (2010) (65)
- Arylsulfatase B Deficiency in Maroteaux-Lamy Syndrome: Cellular Studies and Carrier Identification (1975) (65)
- Transcription-Independent Heritability of Induced Histone Modifications in the Mouse Preimplantation Embryo (2009) (64)
- An association between the kinetic and electrophoretic properties of human purine-nucleoside-phosphorylase isozymes. (1971) (63)
- Histone H4 acetylation and transcription in amphibian chromatin (1993) (61)
- Isozymes of human α-l-fucosidase detectable by starch gel electrophoresis (1974) (60)
- Chromatin and gene regulation : mechanisms in epigenetics (2001) (59)
- Differential underacetylation of histones H2A, H3 and H4 on the inactive X chromosome in human female cells (1996) (58)
- Epigenome changes in active and inactive Polycomb‐group‐controlled regions (2004) (55)
- Genes Are Often Sheltered from the Global Histone Hyperacetylation Induced by HDAC Inhibitors (2012) (53)
- Human inosine triphosphatase: catalytic properties and population studies. (1979) (49)
- The binding of benzyl alcohol to erythrocyte membranes. (1970) (48)
- Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns. (2013) (48)
- Transcription factors, chromatin and cancer. (2009) (46)
- H4 acetylation, XIST RNA and replication timing are coincident and define x;autosome boundaries in two abnormal X chromosomes. (1999) (46)
- Maternal histone deacetylase is accumulated in the nuclei of Xenopus oocytes as protein complexes with potential enzyme activity. (1999) (45)
- Histone H4 acetylation and replication timing in Chinese hamster chromosomes. (1996) (44)
- Islands of acetylated histone H4 in polytene chromosomes and their relationship to chromatin packaging and transcriptional activity. (1990) (42)
- Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response (2015) (42)
- Inhibition of Histone Deacetylases Alters Allelic Chromatin Conformation at the Imprinted U2af1-rs1 Locus in Mouse Embryonic Stem Cells* (2002) (39)
- Euchromatic domains in plant chromosomes as revealed by H4 histone acetylation and early DNA replication. (1999) (38)
- Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase. (2006) (38)
- Nuclear Organization of Mammalian Genomes (1999) (37)
- X-linked genes in female embryonic stem cells carry an epigenetic mark prior to the onset of X inactivation. (2003) (36)
- Altered histone modifications in cancer. (2013) (36)
- Different strategies of X-inactivation in germinal and somatic cells: histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline. (1997) (34)
- Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression (2010) (34)
- Cell-specific differences in membrane beta-glucosidase from normal and Gaucher cells. (1977) (33)
- The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing (2013) (32)
- Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. (1989) (31)
- POST-TRANSLATIONAL ALTERATIONS OF HUMAN ERYTHROCYTE ENZYMES (1975) (31)
- Molecular cloning of Drosophila melanogaster cDNAs that encode a novel histone deacetylase dHDAC3. (1998) (31)
- Studies on human erythrocyte inorganic pyrophosphatase (1974) (29)
- Nucleosome signalling; an evolving concept. (2014) (29)
- Differential immunostaining of plant chromosomes by antibodies recognizing acetylated histone H4 variants (1996) (28)
- Chromatin and Gene Regulation (2001) (27)
- Environmental sensing by chromatin: An epigenetic contribution to evolutionary change (2011) (27)
- Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes (2016) (26)
- Purification and characterisation of alpha-L-fucosidase from human placenta. pH-dependent changes in molecular size. (1979) (26)
- Memorable transcription (2003) (26)
- Fucosidosis: detection of the carrier state in peripheral blood leukocytes. (1975) (26)
- Evolution of dosage compensation (1996) (24)
- Itga2b Regulation at the Onset of Definitive Hematopoiesis and Commitment to Differentiation (2012) (23)
- Elevated FOSB‐expression; a potential marker of valproate sensitivity in AML (2009) (21)
- Open chromatin and hypertranscription in embryonic stem cells. (2008) (20)
- Properties of beta-glucosidase in cultured skin fibroblasts from controls and patients with Gaucher disease. (1978) (20)
- Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells (2012) (19)
- Histone H4 acetylated at lysine 16 and proteins of theDrosophila dosage compensation pathway co-localize on the male X chromosome through mitosis (1994) (18)
- Differential loss of histone H3 isoforms mono-, di- and tri-methylated at lysine 4 during X-inactivation in female embryonic stem cells (2008) (18)
- Activation of V(D)J Recombination at the IgH Chain JH Locus Occurs within a 6-Kilobase Chromatin Domain and Is Associated with Nucleosomal Remodeling1 (2006) (18)
- Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells. (2010) (17)
- α-L-Fucosidase in Cultured Skin Fibroblasts from Normal Subjects and Fucosidosis Patients (1977) (17)
- Secretion ofα1-antitrypsin by an established human hepatoma cell line and by human/mouse hybrids (1980) (16)
- Chromatin structure analysis of the mouse Xist locus. (1999) (15)
- Histone H4, the cell cycle and a question of integrity. (1995) (15)
- Comparative analysis of topographic distribution of acetylated histone H4 by using confocal microscopy and a deconvolution system (1998) (14)
- Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A. (2002) (13)
- Introduction: chromatin--a target for intracellular signalling pathways. (1999) (11)
- Suppression of heat-shock protein synthesis by short-chain fatty acids and alcohols. (1994) (11)
- Immunofluorescent staining of human metaphase chromosomes with monoclonal antibody to histone H2B (2004) (11)
- Improved sample extraction before liquid chromatography of prednisone and prednisolone in human serum. (1982) (11)
- Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis. (1974) (11)
- Assignment of the human alpha-l-fucosidase gene locus to chromosome 1 by use of a "clone panel". (1976) (10)
- The pattern of histone H4 acetylation on the X chromosome during spermatogenesis of the desert locust Schistocerca gregaria. (1996) (10)
- Predictors of Clinical Response in Patients with High Risk Acute Myeloid Leukemia Receiving Treatment with the Histone Deacetylase Inhibitor Sodium Valproate. (2005) (10)
- A New Map for Navigating the Yeast Epigenome (2005) (9)
- Quantitative Microscopic Ionophoresis and Chromatography (1957) (9)
- Regional localization of HLA, MES, and SODM on chromosome 6. (1978) (8)
- Immunofluorescent detection of histone 2B on metaphase chromosomes using flow cytometry (1984) (8)
- Simplifying a complex code (2008) (7)
- Histone acetylation as an epigenetic marker (1998) (7)
- Tomographic distribution of acetylated histone H4 in plant chromosomes, nuclei and nucleoli (1996) (6)
- Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle (2021) (6)
- alpha-L-Fucosidase in normal and deficient individuals. (1976) (6)
- A monoclonal antibody recognizes a phosphorylated epitope shared by proteins of the cell nucleus and the erythrocyte membrane skeleton (1986) (5)
- Human beta-glucosidase: inhibition by sulphates and purification by affinity chromatography on Dextran-sulphate-Sepharose. (1981) (5)
- Transcription in Eukaryotes: The Problems of Complexity (2001) (4)
- Lamarck and the nucleosome: evolution and environment across 200 years (2013) (4)
- Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines (2015) (4)
- Chromatin: Structure and Function, third edition, Alan Wolffe (2000) (4)
- Metabolic correction of fucosidosis fibroblasts by human α‐L‐fucosidase (1979) (4)
- Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs (2020) (3)
- Metabolic correction of fucosidosis fibroblasts by human alpha-L-fucosidase. (1979) (3)
- Preparation of insect chromosomes for immunolabeling. (1996) (3)
- The Nucleosome: Chromatin's Structural Unit (2001) (3)
- Epigenetic Reprogramming in Mammalian Development (2001) (3)
- An investigation of some factors affecting levels of erythrocyte inorganic pyrophosphatase activity. (1975) (2)
- Cu2+ -dependent changes in metaphase chromosome structure assayed by antibody labelling and flow cytometry (1986) (2)
- Quantitative microscopic ionophoresis and chromatography (1958) (2)
- The nucleosome untangled (2006) (2)
- Epigenetics can free us from the tyranny of selfish DNA (2017) (2)
- Explorer Epigenetic engineering : histone H 3 K 9 acetylation is compatible with kinetochore structure and function (2017) (2)
- Antibody labelling and flow cytometric analysis of metaphase chromosomes reveals two discrete structural forms (2004) (2)
- Histone Tails: Modifications and Epigenetic Information (2001) (1)
- Higher-Order Chromatin Structures and Nuclear Organization (2001) (1)
- Patterns of histone H4 acetylation distinguish structural and functional domains within the human genome (1998) (1)
- CROSS TALK BETWEEN HISTONE MODIFICATIONS IN RESPONSE TO HDAC INHIBITORS : MLL 4 LINKS HISTONE H 3 ACETYLATION AND HISTONE H 3 K 4 METHYLATION (2006) (1)
- Characterisation of Drosophila melanogaster histone deacetylases (2000) (1)
- A unified phylogeny-based nomenclature for histone variants (2012) (1)
- Transcription in a Chromatin Environment (2001) (1)
- Decoding the Nucleosome Minireview (1993) (1)
- The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing (2013) (1)
- Nucleosome modifications and their interactions; searching for a histone code (2004) (1)
- Ionophoretic and Chromatographic Analysis of Single Dust Particles (1957) (1)
- Calculation of Frequency of Acetylation at Individual 1-14 Lysines (2002) (0)
- Polymorphism of Human a Fucosidase (2006) (0)
- Chapter 4 Role of histones and their acetylation in control of gene expression (1996) (0)
- Chromatin Remodelling Machines (2001) (0)
- Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes (2016) (0)
- Review Cellular Memory and the Histone Code (2002) (0)
- Properties of /3-Glucosidase in Cultured Skin Fibroblasts from Controls and Patients with Gaucher Disease (2006) (0)
- How the Transcription Machinery Deals With Chromatin (2001) (0)
- Site-specificity and biochemical characterisation of two distinct families of mammalian histone deacetylase complexes (2000) (0)
- Part 2. Detailed Method for Immunoprecipitation of Unfixed Chromatin from Mammalian Cells (2001) (0)
- Identification of Candidate Genes Associated with Sensitivity and Resistance to the Histone Deacetylase Inhibitor Valproic Acid in Patients with Acute Myeloid Leukemia. (2007) (0)
- CHAPTER 2:Enzyme and Protein Families that Regulate Histone Modifications and Crosstalk (2015) (0)
- Mechanisms of Dosage Compensation (2001) (0)
- Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response (2015) (0)
- Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines (2015) (0)
- Controlling Transcription: Shared Aims and Common Mechanisms (2001) (0)
- Subject Index Vol. 22, 1978 (1978) (0)
- Characterisation of Histone Deacetylase (HDAC) Expression Profiles in Acute Myeloid Leukaemia: A Basis for the Development of Targeted Therapy Using Histone Deacetylase Inhibitors. (2004) (0)
- Histone modifications form a cell-type-specific chromosomal bar code that modulates and maintains patterns of gene expression through the cell cycle (2020) (0)
- Associated with Nucleosomal Remodeling 6-Kilobase Chromatin Domain and Is IgH Chain JH Locus Occurs within a Activation of V(D)J Recombination at the (2006) (0)
- COMPARISON OF CRYSTAL STRUCTURES OF INCLUSION COMPLEXES OF DEOXYCHOLIC ACID AND THOSE OF APOCHOLIC ACID (0)
- Assignment of the human alpha-L-fucosidase gene locus to chromosome 1 by use of a "clone panel". (1976) (0)
- Subject Index Vol. 16, 1976 (1976) (0)
- Histone acetylation in mouse embryonic stem cells (1997) (0)
- Dynamics and functional aspects of histone modifications in plants (2000) (0)
- Suppression of 1,25 dihydroxyvitamin D3 signalling in prostate cancer involves histone deacetylation (2002) (0)
- Cellular Memory and Imprinting (2001) (0)
- Long-Term Silencing of Gene Expression (2001) (0)
- Fucosidosis: Detection of the peripheral blood leukocytes carrier state in (1975) (0)
- Abstracts of papers presented at the ninth Mammalian Genetics and De (cid:138) elopment Workshop held at the Institute of Child Health , Uni (cid:138) ersity College London on 1 4– 1 6 December 1 (1999) (0)
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