Bryan Paul Morgan
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Bryan Paul Morgan's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Immunology Stanford University
- Doctorate Immunology Harvard University
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(Suggest an Edit or Addition)Bryan Paul Morgan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells (2013) (938)
- Microfluidic, marker-free isolation of circulating tumor cells from blood samples (2014) (608)
- Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. (1990) (533)
- Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome (2007) (465)
- Multiple sclerosis: In situ evidence for antibody‐ and complement‐mediated demyelination (1998) (439)
- IgG1 antibodies to acetylcholine receptors in ‘seronegative’ myasthenia gravis† (2008) (432)
- Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. (2003) (404)
- Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects. (1989) (380)
- Immunopathology of secondary‐progressive multiple sclerosis (2001) (366)
- Complement components of the innate immune system in health and disease in the CNS. (2000) (353)
- Complement, a target for therapy in inflammatory and degenerative diseases (2015) (322)
- The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement (1991) (313)
- The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation (2013) (308)
- Increased Complement Biosynthesis By Microglia and Complement Activation on Neurons in Huntington's Disease (1999) (302)
- Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. (1997) (260)
- Dimerization of complement factor H-related proteins modulates complement activation in vivo (2013) (255)
- Expression of complement in the brain: role in health and disease. (1996) (253)
- Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement (1989) (244)
- Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines. (1995) (244)
- Recovery of human neutrophils from complement attack: removal of the membrane attack complex by endocytosis and exocytosis. (1987) (236)
- Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis. (1994) (225)
- Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk (2011) (218)
- Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. (2010) (211)
- Complement: central to innate immunity and bridging to adaptive responses. (2005) (210)
- Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. (1994) (210)
- The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis. (1998) (208)
- Beyond lysis: how complement influences cell fate. (2003) (204)
- Complement Regulatory Proteins (1999) (193)
- Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement- mediated lysis (1993) (190)
- Complement deficiency and disease. (1991) (187)
- The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury1 (2002) (185)
- Structural basis of complement membrane attack complex formation (2016) (184)
- Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. (1995) (176)
- Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina* (2010) (171)
- The Human Complement System in Health and Disease. (1998) (170)
- Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria. (2001) (167)
- Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. (2012) (165)
- Complement therapeutics; history and current progress. (2003) (162)
- The role of complement in the pathogenesis of experimental allergic encephalomyelitis. (1989) (161)
- The Glycosylation of the Complement Regulatory Protein, Human Erythrocyte CD59* (1997) (158)
- Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release (2013) (156)
- Sphingomyelinases in the venom of the spider Loxosceles intermedia are responsible for both dermonecrosis and complement-dependent hemolysis. (1998) (154)
- CD46 Plays a Key Role in Tailoring Innate Immune Recognition of Apoptotic and Necrotic Cells* (2005) (152)
- The membrane attack complex as an inflammatory trigger. (2016) (151)
- Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions (2013) (149)
- The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. (2009) (143)
- The human complement fragment receptor, C5L2, is a recycling decoy receptor (2009) (142)
- Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy. (2004) (142)
- Effects of the membrane attack complex of complement on nucleated cells. (1992) (142)
- Regulation of the complement membrane attack pathway. (1999) (140)
- Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis. (2000) (139)
- C3-dependent mechanism of microglial priming relevant to multiple sclerosis (2012) (139)
- Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent (1995) (137)
- Miller Fisher anti‐GQ1b antibodies: α‐Latrotoxin–like effects on motor end plates (1999) (135)
- Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition. (1999) (132)
- The complotype: dictating risk for inflammation and infection (2012) (130)
- Research priorities for the COVID‐19 pandemic and beyond: A call to action for psychological science (2020) (130)
- Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma (2016) (129)
- Human C1qRp Is Identical with CD93 and the mNI-11 Antigen But Does Not Bind C1q1 (2002) (125)
- Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages1 (2009) (123)
- Structural basis for complement factor I control and its disease-associated sequence polymorphisms (2011) (123)
- The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium. (1985) (121)
- Complement in the pathogenesis of Alzheimer’s disease (2017) (120)
- Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation (1989) (120)
- Glycosylation and the complement system. (2002) (119)
- Complement regulation at the molecular level: the structure of decay-accelerating factor. (2004) (118)
- Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System (2019) (118)
- Monoclonal antibodies demonstrate protection of polymorphonuclear leukocytes against complement attack (1985) (118)
- Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis. (2012) (116)
- Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. (1994) (115)
- Complement activation in multiple sclerosis plaques: an immunohistochemical analysis (2014) (115)
- Membrane proteins that protect against complement lysis (2005) (113)
- Apoptosis is associated with reduced expression of complement regulatory molecules, adhesion molecules and other receptors on polymorphonuclear leucocytes: functional relevance and role in inflammation. (1995) (112)
- Holding T cells in check--a new role for complement regulators? (2006) (112)
- Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice (2014) (112)
- CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice (2019) (109)
- Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status. (2007) (108)
- Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B (2009) (107)
- Complement dysregulation and disease: from genes and proteins to diagnostics and drugs. (2012) (106)
- Inflammatory biomarkers in Alzheimer's disease plasma (2019) (104)
- Differential expression of individual complement regulators in the brain and choroid plexus. (1999) (104)
- Complement: Clinical Aspects and Relevance to Disease (1991) (103)
- Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis. (2011) (101)
- Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. (2008) (101)
- Complement Factor H Binds to Denatured Rather than to Native Pentameric C-reactive Protein* (2008) (100)
- Identification and characterization of complement C3 receptors on human astrocytes. (1996) (99)
- Intracellular Ca2+ and cell injury: a paradoxical role of Ca2+ in complement membrane attack. (1986) (98)
- Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59. (1997) (98)
- Complement Regulation by Kaposi's Sarcoma-Associated Herpesvirus ORF4 Protein (2003) (97)
- Normal rat serum cytotoxicity against syngeneic oligodendrocytes Complement activation and attack in the absence of anti-myelin antibodies (1989) (96)
- Molecular Dissection of Interactions between Components of the Alternative Pathway of Complement and Decay Accelerating Factor (CD55)* (2005) (96)
- Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis (2004) (96)
- Complement activation and inhibition in experimental models of arthritis. (1999) (95)
- CD59, a Complement Regulatory Protein, Controls Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration1 (2007) (95)
- Identification of Factor H–like Protein 1 as the Predominant Complement Regulator in Bruch’s Membrane: Implications for Age-Related Macular Degeneration (2014) (95)
- In Vivo Characterization and Therapeutic Efficacy of a C5-specific Inhibitor from the Soft Tick Ornithodoros moubata* (2007) (94)
- Mutational Analysis of the Active Site and Antibody Epitopes of the Complement-inhibitory Glycoprotein, CD59 (1997) (94)
- Human Factor H-related Protein 5 (FHR-5) (2001) (93)
- Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement. (1992) (92)
- Loxosceles intermedia spider envenomation induces activation of an endogenous metalloproteinase, resulting in cleavage of glycophorins from the erythrocyte surface and facilitating complement-mediated lysis. (2000) (91)
- Complement is activated in progressive multiple sclerosis cortical grey matter lesions (2016) (91)
- In vivo effects of monoclonal antibodies that functionally inhibit complement regulatory proteins in rats (1994) (91)
- The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration (2007) (91)
- Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report (2020) (91)
- Miller Fisher anti-GQ1b antibodies: alpha-latrotoxin-like effects on motor end plates. (1999) (88)
- Complement-inhibiting activities of human CD59 and analogues from rat, sheep, and pig are not homologously restricted. (1994) (87)
- Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation (2012) (87)
- Antithyroid drugs and release of inflammatory mediators by complement-attacked thyroid cells (1992) (87)
- CD59a Is the Primary Regulator of Membrane Attack Complex Assembly in the Mouse1 (2004) (85)
- Measurement of terminal complement complexes in rheumatoid arthritis. (1988) (85)
- TERMINAL COMPONENT OF COMPLEMENT (C9) IN CEREBROSPINAL FLUID OF PATIENTS WITH MULTIPLE SCLEROSIS (1984) (83)
- Complement Component C1q Mediates Mitochondria-Driven Oxidative Stress in Neonatal Hypoxic–Ischemic Brain Injury (2010) (83)
- The role of complement in disorders of the nervous system. (1997) (83)
- Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice (2009) (80)
- Complement abnormalities in acquired lipodystrophy revisited. (2009) (79)
- Tissue distribution of complement regulatory membrane proteins in rats. (1994) (79)
- Compendium of current complement therapeutics. (2019) (78)
- Membrane attack complex (MAC)-mediated damage to spermatozoa: protection of the cells by the presence on their membranes of MAC inhibitory proteins. (1992) (77)
- Inhibition of Coxsackie B Virus Infection by Soluble Forms of Its Receptors: Binding Affinities, Altered Particle Formation, and Competition with Cellular Receptors (2005) (76)
- Meningococcal septicaemia in a C6-deficient patient and effects of plasma transfusion on lipopolysaccharide release (1992) (76)
- CD59 protects glomerular endothelial cells from immune-mediated thrombotic microangiopathy in rats. (1998) (75)
- Complement membrane attack complex, perforin, and bacterial exotoxins induce in K562 cells calcium-dependent cross-protection from lysis. (1995) (74)
- Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. (2010) (74)
- Molecular cloning and functional characterization of the pig analogue of CD59: relevance to xenotransplantation. (1998) (74)
- Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site. (1994) (73)
- Cutting Edge: Murine CD59a Modulates Antiviral CD4+ T Cell Activity in a Complement-Independent Manner1 (2005) (70)
- Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement. (1995) (70)
- Physiology and pathophysiology of complement: progress and trends. (1995) (69)
- CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers (2018) (69)
- Therapeutic efficacy of a novel membrane-targeted complement regulator in antigen-induced arthritis in the rat. (2000) (68)
- Oligodendrocyte susceptibility to injury by T-cell perforin. (1990) (68)
- Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis. (2006) (68)
- The expression of complement regulatory proteins by adult human oligodendrocytes (1998) (67)
- Characterization of the membrane attack complex inhibitory protein CD59 antigen on human amniotic cells and in amniotic fluid. (1992) (67)
- Immunohistochemical determination of complement activation in joint tissues of patients with rheumatoid arthritis and osteoarthritis using neoantigen-specific monoclonal antibodies. (1992) (67)
- The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain–Barré syndrome (2008) (67)
- Complement regulatory molecules: application to therapy and transplantation. (1995) (67)
- Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration (2011) (66)
- Generation of a Recombinant, Membrane-targeted Form of the Complement Regulator CD59 (2003) (65)
- The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. (2010) (65)
- An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice (2015) (63)
- The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice (2010) (63)
- Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. (2004) (63)
- Systemic complement profiling in multiple sclerosis as a biomarker of disease state (2012) (63)
- COMPARISONS OF THERAPEUTIC EFFECTS OF LEVODOPA, LEVODOPA AND SELEGILINE, AND BROMOCRIPTINE IN PATIENTS WITH EARLY, MILD PARKINSONS-DISEASE - 3-YEAR INTERIM-REPORT (1993) (63)
- Implication of Complement System and its Regulators in Alzheimer’s Disease (2009) (62)
- Molecular and functional analysis of mouse decay accelerating factor (CD55). (1999) (60)
- Complement Mediated Signaling on Pulmonary CD103+ Dendritic Cells Is Critical for Their Migratory Function in Response to Influenza Infection (2013) (60)
- Role of Complement in the Aetiology of Pick's Disease? (1996) (60)
- Measurement of complement hemolytic activity, generation of complement-depleted sera, and production of hemolytic intermediates. (2000) (59)
- A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 2. Laboratory results. (1987) (59)
- Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis (2011) (59)
- Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP)-2 in the hypoglossal nucleus following peripheral nerve injury. (1995) (58)
- Purification and characterization of the pig analogue of human membrane cofactor protein (CD46/MCP). (1997) (57)
- Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells. (1995) (57)
- Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration (2020) (57)
- Molecular cell biology of complement membrane attack. (2017) (57)
- Human protectin (CD59), an 18-20-kD homologous complement restriction factor, does not restrict perforin-mediated lysis (1990) (56)
- Role of CD59 in experimental glomerulonephritis in rats. (1994) (56)
- Complement mediated cell death is associated with DNA fragmentation (2000) (55)
- Terminal complexes of the complement system: new structural insights and their relevance to function (2016) (54)
- Isolation and characterization of the complement-inhibiting protein CD59 antigen from platelet membranes. (1992) (53)
- Decay-Accelerating Factor (CD55) Is Expressed by Neurons in Response to Chronic but Not Acute Autoimmune Central Nervous System Inflammation Associated with Complement Activation1 (2005) (53)
- Complement system biomarkers in first episode psychosis (2017) (53)
- Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis. (1995) (52)
- Cerebrospinal fluid C9 in demyelinating disease (1986) (52)
- Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice (2010) (52)
- The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome (2015) (51)
- Soluble complement receptor 1 protects the peripheral nerve from early axon loss after injury. (2008) (51)
- Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome. (2010) (51)
- Effects of inhibition of complement activation using recombinant soluble complement receptor 1 on neutrophil CD11b/CD18 and L-selectin expression and release of interleukin-8 and elastase in simulated cardiopulmonary bypass. (1996) (50)
- Complementing the inflammasome (2016) (50)
- A bispecific monoclonal antibody directed against both the membrane-bound complement regulator CD55 and the renal tumor-associated antigen G250 enhances C3 deposition and tumor cell lysis by complement. (1998) (50)
- Hereditary angioedema--therapies old and new. (2010) (50)
- Expression of complement regulatory molecules and other surface markers on neutrophils from synovial fluid and blood of patients with rheumatoid arthritis. (1994) (50)
- Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice* (2010) (49)
- Respective Roles of Decay-Accelerating Factor and CD59 in Circumventing Glomerular Injury in Acute Nephrotoxic Serum Nephritis1 (2004) (49)
- Pigs Express Multiple Forms of Decay-Accelerating Factor (CD55), All of Which Contain Only Three Short Consensus Repeats1 (2000) (48)
- Molecular cloning and functional characterization of the rat analogue of human decay-accelerating factor (CD55). (1998) (48)
- Human skeletal myoblasts spontaneously activate allogeneic complement but are resistant to killing. (1996) (47)
- Complement and complement regulators in the male reproductive system. (2006) (47)
- The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease. (2017) (47)
- Local therapy with soluble complement receptor 1 (sCR1) suppresses inflammation in rat mono-articular arthritis. (1997) (47)
- Membrane complement regulators protect against the development of type II collagen-induced arthritis in rats. (2001) (47)
- CD59a deficiency exacerbates ischemia-reperfusion injury in mice. (2004) (47)
- Complement methods and protocols (2000) (45)
- CD59a deficiency exacerbates accelerated nephrotoxic nephritis in mice. (2003) (44)
- Immunology of reproduction: Protecting the placenta (2000) (44)
- A functional role for corpora amylacea based on evidence from complement studies. (1995) (44)
- CD59 Blockade Enhances Antigen-Specific CD4+ T Cell Responses in Humans: A New Target for Cancer Immunotherapy?1 (2009) (43)
- Comparison between complement and melittin hemolysis: anti-melittin antibodies inhibit complement lysis. (1988) (43)
- Reversible injury of cultured rat oligodendrocytes by complement. (1989) (43)
- The effects of functional suppression of a membrane-bound complement regulatory protein, CD59, in the synovial tissue in rats. (1997) (42)
- A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome. (2016) (42)
- The complement system: an overview. (2000) (42)
- Identification of an Astrocyte Cell Population from Human Brain that Expresses Perforin, a Cytotoxic Protein Implicated in Immune Defense (1998) (42)
- Insights into the Human CD59 Complement Binding Interface Toward Engineering New Therapeutics* (2005) (41)
- Echoviruses and coxsackie B viruses that use human decay-accelerating factor (DAF) as a receptor do not bind the rodent analogues of DAF. (2000) (41)
- Expression and function of multiple regulators of complement activation in autoimmune thyroid disease. (1994) (40)
- Expression and function of membrane attack complex inhibitory proteins on thyroid follicular cells. (1992) (40)
- Rat Membrane Cofactor Protein (MCP; CD46) Is Expressed Only in the Acrosome of Developing and Mature Spermatozoa and Mediates Binding to Immobilized Activated C31 (2004) (40)
- Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease. (2016) (39)
- Zymosan, but Not Lipopolysaccharide, Triggers Severe and Progressive Peritoneal Injury Accompanied by Complement Activation in a Rat Peritonitis Model1 (2009) (39)
- Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. (2011) (39)
- Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease. (1989) (39)
- Role of complement in inflammation and injury in the nervous system. (1997) (38)
- Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNγ-dependent iNOS expression in the vasculature of healthy mice (2008) (38)
- Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation. (2013) (38)
- Development of a model for cytomegalovirus infection of oligodendrocytes. (1997) (38)
- Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay. (2013) (37)
- CD59a deficiency exacerbates influenza-induced lung inflammation through complement-dependent and-independent mechanisms (2007) (37)
- Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay1 (2007) (36)
- Complement Inhibition with the C5 Blocker LFG316 in Severe COVID-19 (2020) (36)
- Enhanced complement susceptibility of avidin-biotin-treated human erythrocytes is a consequence of neutralization of the complement regulators CD59 and decay accelerating factor. (1995) (36)
- Complement inhibition accelerates regeneration in a model of peripheral nerve injury. (2009) (35)
- Stimulation of human rheumatoid synovial cells by non-lethal complement membrane attack. (1990) (35)
- A protein toxin from the sea anemone Phyllodiscus semoni targets the kidney and causes a severe renal injury with predominant glomerular endothelial damage. (2007) (35)
- Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay (2019) (35)
- Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder (2017) (35)
- Terminal complement complexes and C1 C1 inhibitor complexes in rheumatoid arthiritis and other artiritic conditions (1991) (35)
- Tailoring anti-complement therapeutics. (2001) (34)
- Reversible cell damage by T-cell perforins. Calcium influx and propidium iodide uptake into K562 cells in the absence of lysis. (1990) (34)
- Antibody-independent activation of the classical complement pathway by cytomegalovirus-infected fibroblasts. (1998) (34)
- The possibilities and pitfalls for anti-complement therapies in inflammatory diseases. (2004) (34)
- Mechanisms of tissue damage by the membrane attack complex of complement. (1989) (34)
- Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis (2018) (33)
- M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator (2015) (33)
- Molecular bases of combined subtotal deficiencies of C6 and C7: their effects in combination with other C6 and C7 deficiencies. (1996) (33)
- Efficient generation of monoclonal antibodies against surface-expressed proteins by hyperexpression in rodent cells. (1999) (33)
- Complement lysis of U937, a nucleated mammalian cell line in the absence of C9: effect of C9 on C5b-8 mediated cell lysis. (1986) (32)
- CD55 Deficiency Protects against Atherosclerosis in ApoE-Deficient Mice via C3a Modulation of Lipid Metabolism (2011) (32)
- Transfected CD59 protects mesangial cells from injury induced by antibody and complement. (1996) (32)
- The pig analogue of CD59 protects transgenic mouse hearts from injury by human complement. (2000) (32)
- Expression of Human Complement Receptor Type 2 (CD21) in Mice During Early B Cell Development Results in a Reduction in Mature B Cells and Hypogammaglobulinemia1 (2002) (32)
- Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis (2013) (32)
- Immunohistochemical localisation of terminal complement component C9 in experimental allergic encephalomyelitis (2004) (31)
- Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma. (2008) (31)
- Immunoaffinity purification of human complement component C9 using monoclonal antibodies. (1983) (31)
- Role and regulation of pig CD59 and membrane cofactor protein/CD46 expressed on pig aortic endothelial cells. (2000) (31)
- The sheep analogue of human CD59: purification and characterization of its complement inhibitory activity. (1993) (31)
- p53 regulates cellular resistance to complement lysis through enhanced expression of CD59. (2006) (31)
- Efficient generation of monoclonal antibodies for specific protein domains using recombinant immunoglobulin fusion proteins: pitfalls and solutions. (2002) (31)
- Structure of Human Complement C8, a Precursor to Membrane Attack (2011) (30)
- Immunolocalization of complement component C9 on necrotic and non-necrotic muscle fibres in myositis using monoclonal antibodies: a primary role of complement in autoimmune cell damage. (1984) (30)
- Genetic analysis and functional characterization of novel mutations in a series of patients with atypical hemolytic uremic syndrome. (2016) (30)
- Expression of the glycosylphosphatidylinositol-linked complement-inhibiting protein CD59 antigen in insect cells using a baculovirus vector. (1993) (30)
- Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. (2009) (29)
- The role of complement in neurological and neuropsychiatric diseases (2015) (29)
- Mapping the regions of the complement inhibitor CD59 responsible for its species selective activity. (1997) (29)
- Properties of a low molecular weight complement component C6 found in human subjects with subtotal C6 deficiency. (1992) (29)
- The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility (2008) (29)
- The Distribution of Inflammatory Demyelinated Lesions in the Central Nervous System of Rats with Antibody-Augmented Demyelinating Experimental Allergic Encephalomyelitis (1994) (29)
- Prevention of experimental autoimmune myasthenia gravis by rat Crry-Ig: A model agent for long-term complement inhibition in vivo (2008) (29)
- Glomerular complement regulation is overwhelmed in passive Heymann nephritis. (2001) (28)
- A Humanized Antibody That Regulates the Alternative Pathway Convertase: Potential for Therapy of Renal Disease Associated with Nephritic Factors (2014) (28)
- Elevated plasma C4a levels in multiple sclerosis correlate with disease activity (2010) (28)
- Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes. (2002) (27)
- GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface. (2002) (27)
- Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice (2011) (27)
- Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity1 (2006) (27)
- A case of hereditary combined deficiency of complement components C6 and C7 in man. (1989) (27)
- Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration (2010) (27)
- Purification of C8 and C9 from rat serum. (1990) (27)
- The role of calcium in rat oligodendrocyte injury and repair (1992) (27)
- Complement mediated serum cytotoxicity against oligodendrocytes: a comparison with other cells of the oligodendrocyte-type 2 astrocyte lineage (1990) (27)
- Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration. (2009) (26)
- Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis (2018) (26)
- Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat (1998) (26)
- High-resolution structures of bacterially expressed soluble human CD59. (2007) (26)
- The Administration of Complement Component C9 Enhances the Survival of Neonatal Rats with Escherichia coli Sepsis1 (1997) (25)
- A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. (2012) (25)
- CD93 regulates central nervous system inflammation in two mouse models of autoimmune encephalomyelitis (2018) (25)
- Development of a high-throughput SARS-CoV-2 antibody testing pathway using dried blood spot specimens (2020) (25)
- Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats. (2012) (24)
- Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial (2015) (24)
- Killing of gram-negative bacteria by complement. Fractionation of cell membranes after complement C5b-9 deposition on to the surface of Salmonella minnesota Re595. (1989) (24)
- In vivo and in vitro evidence of cell recovery from complement attack in rheumatoid synovium. (1988) (24)
- Coxsackie B viruses that use human DAF as a receptor infect pig cells via pig CAR and do not use pig DAF. (2002) (24)
- Exploiting the Nephrotoxic Effects of Venom from the Sea Anemone, Phyllodiscus semoni, to Create a Hemolytic Uremic Syndrome Model in the Rat (2012) (24)
- Role of the Complement Pathway in Inflammatory Skin Diseases: A Focus on Hidradenitis Suppurativa. (2019) (24)
- Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease (2018) (24)
- 2-Chloroadenosine inhibits complement-induced reactive oxygen metabolite production and recovery of human polymorphonuclear leucocytes attacked by complement. (1985) (23)
- Complement system biomarkers in epilepsy (2018) (23)
- Assembly and Regulation of the Membrane Attack Complex Based on Structures of C 5 b 6 and sC 5 b 9 (2012) (23)
- Identification of the Individual Residues That Determine Human CD59 Species Selective Activity* (1999) (22)
- A rapid method for the isolation of analogues of human CD59 by preparative SDS-PAGE: application to pig CD59. (1995) (22)
- Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. (2011) (22)
- The preparation and characterization of monoclonal antibodies to human complement component C8 and their use in purification of C8 and C8 subunits. (1988) (22)
- Baseline high levels of complement component 4 predict worse clinical outcome at 1-year follow-up in first-episode psychosis (2020) (22)
- Peripheral immune markers and antipsychotic non-response in psychosis (2021) (22)
- Decay-Accelerating Factor (CD55) Is Expressed by Neurons in Response to Chronic but Not Acute Autoimmune Central Nervous System Inflammation Associated with Complement Activation (2005) (22)
- Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation (2010) (21)
- Protection of human amniotic epithelial cells (HAEC) from complement-mediated lysis: expression on the cells of three complement inhibitory membrane proteins. (1990) (21)
- Human rheumatoid synovial cell stimulation by the membrane attack complex and other pore-forming toxins in vitro: the role of calcium in cell activation. (1990) (20)
- A Novel Mutation in a Patient with a Deficiency of the Eighth Component of Complement Associated with Recurrent Meningococcal Meningitis (2009) (20)
- The ninth complement component in rheumatoid arthritis, Behçet's disease and other rheumatic diseases. (1986) (20)
- Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage (2019) (20)
- Role of complement and potential of complement inhibitors in myasthenia gravis and neuromyelitis optica spectrum disorders: a brief review (2019) (20)
- CD59 protects rat kidney from complement mediated injury in collaboration with crry. (2000) (20)
- Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice (2016) (20)
- Local inflammation caused by a monoclonal antibody that blocks the function of the rat membrane inhibitor of C3 convertase. (1996) (20)
- Structure-Function Studies of the Complement System (2002) (19)
- Inhibition of complement-induced [14C]sucrose release by intracellular and extracellular monoclonal antibodies to C9: evidence that C9 is a transmembrane protein. (1984) (19)
- Prevalence of mutations leading to complete C6 deficiency (C6Q0) in the Western Cape, South Africa and detection of novel mutations leading to C6Q0 in an Irish family. (2007) (19)
- Complement Membrane Attack and Tumorigenesis (2016) (19)
- Regulation of CD59 expression on K562 cells: effects of phorbol myristate acetate, cross-linking antibody and non-lethal complement attack. (1995) (19)
- Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59 (2009) (18)
- Generation of Anti-complement “Prodrugs” (2003) (18)
- Complement-mediated lysis of pigeon erythrocyte ghosts analysed by flow cytometry. Evidence for the involvement of a 'threshold' phenomenon. (1983) (17)
- Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins That Use Human CD55 (Decay-Accelerating Factor) as a Receptor Does Not Bind the Rodent and Pig Analogues of CD55 (2004) (17)
- Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH (2013) (17)
- Complement in diseases of the nervous system (1993) (17)
- Target-sensitive immunoerythrocytes: interaction of biotinylated red blood cells with immobilized avidin induces their lysis by complement. (1996) (17)
- Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex. (2016) (17)
- Immunoradiometric assay for human complement component C9 utilising monoclonal antibodies. (1983) (16)
- Complement regulator CD59 deficiency fails to augment susceptibility to actively induced experimental autoimmune myasthenia gravis (2006) (16)
- Characterization of a glycosyl-phosphatidylinositol anchor-deficient subline of Raji cells. An analysis of the functional importance of complement inhibitors on the Raji cell line. (1995) (16)
- Variation in complement component C1 inhibitor in age-related macular degeneration. (2012) (16)
- Membrane attack complex formation on yeast as trigger of selective release of terminal complement proteins from human polymorphonuclear leukocytes. (2000) (16)
- Recovery of polymorphonuclear leucocytes from complement attack (1984) (16)
- Intervention in the complement system: a therapeutic strategy in inflammation. (1996) (16)
- 71Mutations in complement factor B are associated with atypical hemolytic uremic syndrome (2007) (16)
- An “Outside-In” and “Inside-Out” Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases (2021) (15)
- Non-lethal complement-membrane attack on human neutrophils: transient cell swelling and metabolic depletion. (1988) (15)
- Molecular pathogenesis of human CD59 deficiency (2018) (15)
- Development and characterization of novel anti‐C5 monoclonal antibodies capable of inhibiting complement in multiple species (2019) (15)
- A Novel Antibody against Human Factor B that Blocks Formation of the C3bB Proconvertase and Inhibits Complement Activation in Disease Models (2014) (15)
- B Cells from Mice Prematurely Expressing Human Complement Receptor Type 2 Are Unresponsive to T-Dependent Antigens 1 (2005) (15)
- Cerebrospinal fluid complement system biomarkers in demyelinating disease (2019) (15)
- Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers. (2018) (14)
- Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer’s Disease Multimodal Biomarker Discovery Cohort (2020) (14)
- Therapeutic uses of recombinant complement receptors. (1998) (14)
- SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies (2022) (14)
- Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease (2020) (14)
- CD 59 a Is the Primary Regulator of Membrane Attack Complex Assembly in the Mouse 1 (2004) (13)
- Expression of CD46 in Developing Rat Spermatozoa: Ultrastructural Localization and Utility as a Marker of the Various Stages of the Seminiferous Tubuli1 (2005) (13)
- Glycosylation and the Complement System (2002) (13)
- Spermatogenic cells distal to the blood-testis barrier in rats lack C3 convertase regulators and may be at risk of complement-mediated injury. (2006) (13)
- Complement and Humoral Adaptive Immunity in the Human Choroid Plexus: Roles for Stromal Concretions, Basement Membranes, and Epithelium (2016) (13)
- Role of complement C9 and calcium in the generation of arachidonic acid and its metabolites from rat polymorphonuclear leukocytes. (1987) (13)
- Human C 1 qRp Is Identical with CD 93 and the mNI-11 Antigen But Does Not Bind C 1 q 1 (2002) (12)
- Photoproteins as indicators of intracellular free Ca2+. (1989) (12)
- Complement, roles in renal disease and modulation for therapy. (2008) (12)
- Characterizing a pH‐switch anti‐C5 antibody as a tool for human and mouse complement C5 purification and cross‐species inhibition of classical and reactive lysis (2018) (12)
- Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU). (2010) (12)
- Monoclonal Antibodies Capable of Inhibiting Complement Downstream of C5 in Multiple Species (2020) (12)
- High Levels of Soluble C5b-9 Complex in Dialysis Fluid May Predict Poor Prognosis in Peritonitis in Peritoneal Dialysis Patients (2017) (12)
- Imaging Ca2+ changes in individual oligodendrocytes attacked by T-cell perforin. (1991) (12)
- C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection (2019) (11)
- Introduction to complement in health and disease: novel aspects and insights (2018) (11)
- Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study (2021) (11)
- Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line. (1994) (11)
- Impaired Binding of the Amd-Associated Complement Factor H 402h Allotype to Bruch’s Membrane in Human Retina (2010) (11)
- Killing of cells by perforin. Resistance to killing is not due to diminished binding of perforin to the cell membrane. (1991) (11)
- Immunolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells. (1993) (11)
- Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s disease (2022) (11)
- Cell surface regulators of complement, 5I2 antigen, and CD59, in the rat eye and adnexal tissues. (1999) (10)
- Complement system activation contributes to the ependymal damage induced by microbial neuraminidase (2016) (10)
- The Impact of Complement Genes on the Risk of Late-Onset Alzheimer’s Disease (2021) (10)
- Structure–Function Relationships in CD59 (2005) (10)
- Development of adenovirus vectors encoding rat complement regulators for use in therapy in rodent models of inflammatory diseases. (1999) (10)
- Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9. (2017) (10)
- ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies (2021) (10)
- Expression of the C1q/MBL/SPA receptor involved in phagocytosis and innate immune defense on human glia (1998) (10)
- Complement regulator factor H in multiple sclerosis (2011) (9)
- Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model (2019) (9)
- Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression. (2012) (9)
- Structures of the rat complement regulator CrrY (2011) (9)
- Measurement of C9 concentrations using an immunochemiluminometric assay. (1985) (9)
- Into the third century of complement research. (2000) (9)
- The effect of soluble complement receptor 1 (sCR1) and human thyroid antibodies on the course of experimental autoimmune thyroiditis in rats. (1996) (9)
- Novel Small-Molecule Inhibitors Targeting Complement Factor D for Therapy of Paroxysmal Nocturnal Hemoglobinuria (2014) (9)
- Complement activation in postpartum thyroiditis. (2002) (9)
- CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens. (2007) (8)
- Genomic structure and chromosome location of the gene encoding mouse CD59 (2000) (8)
- The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade (2021) (8)
- Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59 (2019) (8)
- Complement in Inflammation (2001) (8)
- The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome (2022) (7)
- The glycosylation of the complement regulatory protein, human erythrocyte CD59. (1997) (7)
- Characterization of a large genomic deletion in four Irish families with C7 deficiency. (2012) (7)
- Immunization with autologous CD46 generates a strong autoantibody response in rats that targets spermatozoa. (2007) (7)
- Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5 (2020) (7)
- Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder (2019) (7)
- Targeting complement in neurodegeneration: challenges, risks, and strategies. (2022) (6)
- Understanding the Immune Protection Afforded by Endogenous Complement Regulatory Molecules (2001) (6)
- Cellular responses to the membrane attack complex (1993) (6)
- CD55 in rat male reproductive tissue: differential expression in testis and expression of a unique truncated isoform on spermatozoa. (2007) (6)
- Complement activation in leprosy: a retrospective study shows elevated circulating terminal complement complex in reactional leprosy (2016) (6)
- Molecular and functional analysis of mouse decay accelerating factor ( CD 55 ) (1999) (6)
- Terminal complement pathway activation drives synaptic loss in Alzheimer’s disease models (2022) (6)
- Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms (2010) (6)
- Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics (2020) (5)
- Cerebrospinal Fluid Complement Components in Multiple Sclerosis (1987) (5)
- Genetic Insights into the Impact of Complement in Alzheimer’s Disease (2021) (5)
- A novel mouse model expressing human forms for complement receptors CR1 and CR2 (2019) (5)
- Exogenous CD59 incorporated into U937 cells through its glycosyl phosphatidylinositol anchor becomes associated with signalling molecules in a time dependent manner. (1995) (5)
- The Many Faces of the Membrane Regulators of Complement (2004) (5)
- Expression of C3aR in man and mouse: predominance in adrenal gland, skin and lung (1998) (5)
- Immunoaffinity methods for purification of complement components and regulators. (2000) (5)
- Non-lethal doses of antibody and complement stimulate release of prostaglandin E2 from human amniotic cells in vitro. (1990) (5)
- Altered glycosylation and selected mutation in recombinant human complement component C9: effects on haemolytic activity. (1994) (4)
- Comparative susceptibility of peripheral blood leucocytes and related cell lines to killing by T-cell perforin. (1994) (4)
- Roles for glycosylation in the anti-inflammatory molecule CD59. (1997) (4)
- A quantitative method for comparison of expression of alternatively spliced genes using different primer pairs. (2006) (4)
- Inhibition of Complement in the Membrane Attack Pathway (2000) (4)
- Presence of a membrane attack complex inhibiting protein on the human epithelial cell line HeLa. (1990) (4)
- Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features (2022) (4)
- Binding of factor H to C-reactive protein occurs only when the latter has undergone non-physiologic denaturation (2007) (4)
- Specific collaboration between rat membrane complement regulators, Crry and CD59, protects peritoneum from damage by autologous complement activation in peritoneal dialysate fluid (2009) (4)
- NEUROINFLAMMATION: MECHANISMS AND MANAGEMENT. (1999) (4)
- Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q (2021) (3)
- C3 Glomerulopathy and Related Disorders in Children (2021) (3)
- Development of a membrane-targeted complement inhibitor for clinical use (2000) (3)
- O35Factor H allele-specific quantification in Tyr402His heterozygotes reveals the existence of low-expression alleles associated with atypical haemolytic uraemic syndrome (2007) (3)
- Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030 (2021) (3)
- Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19 (2022) (3)
- C3aR is a marker of inflammation and gliosis in human neurodegenerative disorders (1998) (3)
- Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer’s Disease Pathology (2020) (3)
- Derivatization of soluble human CD59 with a myristoylated peptide creates a potent membrane-bound inhibitor of complement-mediated lysis (2000) (3)
- Manipulating immune pathways differentially impact emotionality: dissociable effects of complement C3 and C3aR on learned fear and innate anxiety (2019) (3)
- Knocking out mouse CD59 using a PCR derived gene targeting vector (2000) (3)
- Complement factor I deficiency (2020) (3)
- Signalling through neutrophil Fc gamma RIII, Fc gamma RII, and CD59 is not impaired in active rheumatoid arthritis. (1996) (3)
- Letter in response to A. Agrawal: 'CRP after 2004'. (2006) (2)
- Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene (2018) (2)
- Development of EndoScreen Chip, a Microfluidic Pre-Endoscopy Triage Test for Esophageal Adenocarcinoma (2021) (2)
- Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration (2020) (2)
- Affinity Purification of Human Factor H on Polypeptides Derived from Streptococcal M Protein: Enrichment of the Y402 Variant (2013) (2)
- Complement biomarkers in the management of peritoneal dialysis (2016) (2)
- Comparison of the suppressive effects of soluble CR1 and C5a receptor antagonist in acute synovitis induced by anti-rat CD59 antibody (1998) (2)
- 2-Chloroadenosine inhibits complement-induced reactive oxygen metabolite production and recovery of human polymorphonuclear leucocytes attacked by complement (1985) (2)
- A new strategy for protection of neurons from complement-mediated degeneration triggered by β-amyloid plaques (2008) (2)
- Characterisation of expression of complement receptor type 4 (CR4) by human glia (1998) (2)
- Tissue distribution of mouse CD59 analyzed using a novel rat anti-mouse CD59 monoclonal antibody (2000) (2)
- Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration (2019) (2)
- Retraction: Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms (2011) (2)
- Non-lethal effects of perforin on polymorphonuclear leukocytes. (1998) (2)
- Abi3 regulates microglial ramification and dynamic tissue surveillance in vivo (2021) (2)
- Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice (2022) (2)
- C3 Glomerulopathy and Related Disorders in Children Etiology-Phenotype Correlation and Outcomes (2021) (2)
- Novel C3 mutations associated with atypical haemolytic uraemic syndrome (2008) (2)
- THE MECHANISM OF ACTION OF PROTECTIN (CD59), A HOMOLOGOUS RESTRICTION FACTOR OF THE HUMAN-COMPLEMENT SYSTEM (1990) (2)
- The common C3F/S polymorphism, R102G, alters factor H regulation of the alternative pathway convertase and combines with other complement variants to influence complement activity in plasma (2010) (2)
- Effects of inhibition of complement activation using recombinant soluble CR1 on neutrophil CD1 1b/CD18 and L-selectin expression and release of IL8 and elastase in simulated cardiopulmonary bypass (1996) (2)
- Tumor Cell Lysis by Complement Antigen G250 Enhances C3 Deposition and Regulator CD55 and the Renal Tumor-Associated Against Both the Membrane-Bound Complement A Bispecific Monoclonal Antibody Directed (1998) (2)
- Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation (2017) (2)
- Professor Sir Peter J. Lachmann, FRS, FMedSci (1931–2020) (2021) (1)
- Targeting C/EBPβ sensitises tumours to killing via complement-dependent and complement-independent mechanisms (2011) (1)
- Tailoring anticomplement therapeutics (2002) (1)
- Tissue expression pattern of the mouse GPI-DAF and its potential role in a murine model of autoimmune disease (2000) (1)
- Bacterial expression and membrane-targeting of rat CD59 for use in anti-complement therapy (2002) (1)
- Effects of soluble complement receptor 1 (SCR1) on antibody-mediated demyelination in experimental allergic encephalomyelitis (EAE) (1993) (1)
- Complement component 5 deficiency (C5D) in South Africa (2011) (1)
- A novel monoclonal antibody specific for the 402His variant of complement factor H enables identification of the Tyr402His polymorphic status in serum samples (2007) (1)
- Complement biomarkers in Alzheimer's disease (2017) (1)
- Purification of S protein (vitronectin) by a one-step immunoaffinity chromatography procedure (1989) (1)
- Factor H Polymorphism in the diagnosis and therapy of inflammatory diseases such as macular degeneration age-related (2008) (1)
- The monoclonal antibody, 3E7, is a multi-functional inhibitor of the alternative pathway that blocks NeF-triggered activation (2010) (1)
- Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation (2013) (1)
- Signalling through neutrophil Fc-yRIII, FcyRII, and CD59 is not impaired in active rheumatoid arthritis (1)
- Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS (2014) (1)
- Lysis of U937, a nucleated mammalian cell line by complement in the absence of C9 (1985) (1)
- Expression of the terminal pathway of complement by human glial cells (1994) (1)
- The Role of Complement in EAE (2005) (1)
- Human C3 mutation associated with Dense Deposit Disease unravels distinct structural requirements for factor H, MCP and DAF regulation (2010) (1)
- Deletion of the gene encoding C3 decreases disease severity in a murine model of rheumatoid arthritis (2001) (1)
- Targeting sites of complement activation by engineering selective drug delivery (2009) (1)
- CONTRIBUTION OF ENDOGENOUS PIG COMPLEMENT REGULATORY MOLECULES (2000) (1)
- Assignment1 of MCP encoding the porcine membrane cofactor protein (MCP/CD46) to the long arm of pig chromosome 9 with somatic cell hybrids (1999) (1)
- Complement activation in multiple sclerosis plaques: an immunohistochemical analysis (2014) (1)
- Pigs express multiple forms of decay accelerating factor (CD55), all of which contain only three Short Consensus Repeats (SCR) (2000) (1)
- Role of the phagocytic C1qR (C1qRp) in the CNS: Identification of the signalling events following C1pRp crosslinking (2000) (1)
- Role and expression of endogenous CD59 and MCP on pig aortic endothelial cells (1998) (1)
- Local Anti-C5 Therapy Suppresses Experimental Choroidal Neovascularization Through Reduction Of Macrophage Infiltrate (2012) (1)
- Complement and neuronal damage in deep grey matter multiple sclerosis lesions (2011) (1)
- Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex. (2022) (1)
- Pig MCP is a better cofactor for human factor I in the degradation of human C3, than human MCP (1998) (1)
- Complement component C6 deficiency in the Western Cape, South Africa; segregation of four genetic defects (2007) (1)
- Response to Comment on “Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis” (2015) (1)
- Emre Ozkumur Sorting of Rare Circulating Tumor Cells Independent − Dependent and − Inertial Focusing for Tumor Antigen (2013) (1)
- Soluble complement receptor 1 (sCR1) protects the peripheral nerve from early axon loss after injury and facilitates regeneration (2007) (1)
- The ring-like classical complement lesion is not the functional pore of the membrane attack complex (1987) (1)
- A role for CD59a in the progression of atherosclerosis: The first direct evidence from an in vivo study (2007) (1)
- The role of the complement system in nerve damage in leprosy (2011) (1)
- Tissue factor: A link between inflammation and thrombosis in antiphospholipid antibody-induced pregnancy loss (2007) (1)
- Injury in Mice Neurologic Recovery after Traumatic Brain Secondary Neuroaxonal Loss and Promotes of the Complement System Reduces Inhibition of the Membrane Attack Complex (2014) (1)
- Functional differences between common factor B polymorphic variants: An explanation for association with AMD (2008) (1)
- DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN AND ALZHEIMER’S DISEASE PROGRESSION (2018) (1)
- Complement factor C 5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model (2019) (1)
- Complement UK--how and why it started. (2012) (1)
- The terminal pathway of complement in hepatic ischemia/reperfusion injury and regeneration (2010) (1)
- Chapter 34 – CD59 (2018) (1)
- Unresponsive to T-Dependent Antigens Human Complement Receptor Type 2 Are B Cells from Mice Prematurely Expressing (2005) (1)
- The yin and yang of the complement cascade in glaucoma – the importance of timing and location (2016) (1)
- nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis—protocol for a prospective multicohort study (2021) (1)
- Structural studies of human CD59 and its ligands (2007) (1)
- Complement is activated in progressive multiple sclerosis cortical grey matter lesions (2016) (1)
- Complement C6 deficiency delays degeneration and facilitates axonal regeneration and recovery in a model of peripheral nerve injury (2007) (1)
- The Complement System (2nd revised edn) (1999) (0)
- Decay accelerating factor (CD55): the structure of an intact human complement regulator. (2004) (0)
- Complex beauty complements membrane attack (2016) (0)
- Blood plasma biomarkers improve prediction accuracy over and above genetic predictors of Alzheimer’s disease (2022) (0)
- Measurement of factor H and the Y402H polymorphism in Alzheimer's disease (2008) (0)
- Tissue distribution of CD59 in the pig (1998) (0)
- The membrane attack complex (MAC) of complement causes severe demyelination in vivo. Evidence from C6 deficient rats (2000) (0)
- Role of Complement Regulatory Protein, CD59, in the Development of Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration (2007) (0)
- 258 Expression of cytotoxic innate immune molecules by human and rodent glial cells in culture and in demyelinating disorders (1998) (0)
- Characterisation of the high affinity interaction between the human complement regulator CD59 and the Staphylococcus intermedius toxin, intermedilysin (2007) (0)
- CD59 Deficiency Exacerbates Accelerated Nephrotoxic Nephritis (2003) (0)
- Use in Therapy in Rodent Models of Encoding Rat Complement Regulators for Development of Adenovirus Vectors (2013) (0)
- High levels of soluble CD59 in CSF compared to plasma suggests intrathecal source of soluble CD59 (2017) (0)
- RO7112689, a pH-switch anti-C5 mAb, for efficient cross-species C5 purification and inhibition of classical and reactive lysis (2018) (0)
- Effect of membrane anchor type on cell activation induced by cross-linking of CD59 (1998) (0)
- CD59b is expressed at low level on mouse erythrocytes and has a negligible protective role in the presence of CD59a (2004) (0)
- Retraction notice to “The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility” [Mol. Immunol. 45 (2008) 534–542] (2014) (0)
- Crystallisation and preliminary characterisation of crystals of complement component proteins (2004) (0)
- Complement Deposition Membrane-Attack Complex Protects Vascular Endothelial Cells Against Induction of Decay-Accelerating Factor by Cytokines or the (2013) (0)
- EndoScreen Chip: Serum Complement C9 Immunoassays Improve Risk Prediction and Early Diagnosis of Esophageal Adenocarcinoma (2021) (0)
- Structural analysis of the soluble C5b-9 complex using cryo-electron microscopy (2007) (0)
- Complement-Independent Manner Antiviral CD4+ T Cell Activity in a Cutting Edge: Murine CD59a Modulates (2013) (0)
- Therapeutic Agents for Hereditary Angioedema [Letter] (2011) (0)
- Mechanisms responsible for differential Neisseria meningitidis bactericidal activities of human and rabbit complement (2015) (0)
- CD59 blockade on human CD4+ T cells leads to marked enhancement of antigen-specific responses (2008) (0)
- Post-translational modification of complement anaphylatoxins during chronic neutrophilic inflammation (2017) (0)
- Comparison of expression profiles from wildtype and C6 deficient peripheral nerves after crush injury (2010) (0)
- Unravelling the Mechanism of Membrane Attack Complex Pore Closure (2017) (0)
- Functional Analyses Demonstrate that Common Polymorphisms in C3, Factor B and Factor H Collaborate to Determine Systemic Complement Activity and Risk for AMD (2011) (0)
- A role for the complement alternative pathway in the pathology of multiple sclerosis grey matter lesions (2014) (0)
- Complement factor H Ile62 polymorphism increases binding affinity for C3b and enhances cofactor activity (2009) (0)
- Neuroblastoma: Antibody-Based Immunotherapy (2012) (0)
- Kinetic analysis of the interaction between the complement regulators CD46 and CD55 and components of the alternative pathway of complement (2004) (0)
- Production of rat CD59 and chimeric CD59-CRRY as active soluble proteins in Pichia pastoris (1998) (0)
- Deficiency of the fifth component of complement in a young South African woman; three putative genetic defects (2007) (0)
- IgG subclasses of disease-specific antibodies and complement activation in-vitro in seronegative myasthenia gravis and neuromyelitis optica (2008) (0)
- Basic science232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function (2012) (0)
- Short communication Complement regulator CD59 deficiency fails to augment susceptibility to actively induced experimental autoimmune myasthenia gravis (2006) (0)
- The C9 risk variant P167S and age-related macular degeneration (2018) (0)
- 1 Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis (2017) (0)
- Critical role for the membrane attack complex in embryonic lethality in Crry knockout mice (2007) (0)
- Complement: new therapies and emergence of the complotype (2013) (0)
- Compromised expression of the complement membrane inhibitor CD59a propagates age-related joint degeneration in mice [Poster Abstract] (2011) (0)
- Complement inhibitory activity of decay accelerating factor (DAF; CD55) is not species restricted (2000) (0)
- Influenza-induced immunopathology in Cd59a−/− mice (2007) (0)
- Transience of membrane channels induced by perforin and by the membrane attack complex. (1990) (0)
- CD59b is abundantly expressed only in testis and plays a role in acrosome activation and spermatozoal motility (2007) (0)
- ROLE AND REGULATION OF PIG CD59 AND MEMBRANE COFACTOR PROTEIN/CD46 EXPRESSED ON PIG AORTIC ENDOTHELIAL CELLS1 (2000) (0)
- Serum Nephritis Glomerular Injury in Acute Nephrotoxic Factor and CD59 in Circumventing Respective Roles of Decay-Accelerating (2004) (0)
- Complement component C7 deficiency in four Irish families: the characterisation of a large genomic deletion within the C7 gene (2009) (0)
- Introduction to complement in health and disease: novel aspects and insights (2018) (0)
- Complement C3 and C3aR differentially impact on learned fear and innate anxiety (2019) (0)
- Improving decay-accelerating factor (DAF, CD55) by substituting a GPI-anchor with a membrane-targeting address (2001) (0)
- Effect of inhibitors of tyrosine kinase and phospholipase C on neutrophil response to perforin attack (1996) (0)
- Development and characterisation of a novel anti-C5 monoclonal antibody capable of inhibiting complement in multiple species (2018) (0)
- Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial (2015) (0)
- Complement components as biomarkers of disease in multiple sclerosis (2008) (0)
- Therapeutic inhibition of MAC by a C5-specific inhibitor (OmCI) engineered for extended half-life in vivo (2009) (0)
- Complement regulator factor H (fH) levels in CSF of mild cognitive impairment (MCI) cases depend on the Y402H polymorphism (2011) (0)
- Target for Cancer Immunotherapy? T Cell Responses in Humans: A New + CD4CD59 Blockade Enhances Antigen-Specific (2009) (0)
- Non-physiological osmolarity and pH in peritoneal dialysis fluid impair complement regulation in rat peritoneal mesothelial cells (2011) (0)
- Membrane complement regulators may protect against encapsular peritoneal sclerosis (EPS) in a chronic proliferative peritoneal inflammation model of zymosan peritonitis in the rat (2010) (0)
- Different complement immune pathways mediate innate and learned aversion (2020) (0)
- Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement (2012) (0)
- Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis (2018) (0)
- Molecular cloning and characterisation of the rat homologue of human membrane cofactor protein (1998) (0)
- P84Anti-C1q autoantibody in childhood mesangiocapillary glomerulonephritis (2007) (0)
- Terminal complement pathway activation drives synaptic loss in Alzheimer’s disease models (2022) (0)
- Generation of a transgenic mouse expressing a human gain-of-function factor B mutation associated with atypical Hemolytic Uremic Syndrome (2010) (0)
- Immunisation with CD46 generates a strong autoantibody response targeting the spermatozoal acrosome in rat (2007) (0)
- Comparison of CD59 expression on circulating cells of human, rat, mouse and pig (1998) (0)
- Correction (2009) (0)
- POI08 Serum C4a levels in multiple sclerosis correlate with disease activity (2010) (0)
- 238. Investigation of a Complement Polymorphism Associated with Rheumatoid Arthritis (2014) (0)
- Repeats Which Contain Only Three Short Consensus Decay-Accelerating Factor ( CD 55 ) , All of Pigs Express Multiple Forms of (2000) (0)
- Presence of a membrane attack complex inhibiting protein in biological fluids (1989) (0)
- Myasthenia gravis thymus: Complement attack on epithelial and myoid cells (2007) (0)
- Complement Regulation and the Host Response to Infection (2001) (0)
- Neuromyelitis optica IgG in the cerebrospinal fluid induces astrocytopathy in optic nerve (2015) (0)
- Global gene expression analysis of the effects of sublytic complement on CT26 colon carcinoma cells using microarray technology (2012) (0)
- Chapter 22 – C9 (2018) (0)
- Identification of blood-based complement biomarkers in Alzheimer's disease (2012) (0)
- In vitro and in vivo inhibition of anti-gal secreting cells. (2000) (0)
- The Disease-associated Glycosaminoglycan-binding (Y402H) Region Of Complement Factor H Mediates Host Recognition Of Human Bruch’S Membrane And Choroid: Implications Of Age-related Macular Degeneration (2012) (0)
- COMPLEMENT ACTIVATION IN MS: AN IMMUNOHISTOCHEMICAL ANALYSIS (2014) (0)
- Genomic disorders associated with aHUS (2009) (0)
- Terminal complement pathway therapy in experimental traumatic brain injury (2012) (0)
- CD59 an unexpected protective role in bone (2011) (0)
- Hunting for biomarkers: The complement system in Alzheimer's disease (2012) (0)
- Complement activation and cell activation in the Alzheimer brain (2012) (0)
- Crry deficiency exacerbates atherosclerosis in apoE deficient mice (2012) (0)
- Local and not systemic factor H production dictates risk of age-related macular degeneration in liver transplant recipients (2012) (0)
- Identification of plasma proteome signatures associated with ATN framework using SOMAscan (2020) (0)
- Complement inhibition is neuroprotective in a mouse model of leprosy (2012) (0)
- The role of SERPING1 in age related macular degeneration (2009) (0)
- Clinical and immunological correlates in myasthenia gravisassociated with musk antibodies [Abstract] (2008) (0)
- COMPLEMENT REGULATORY MOLECULES: AN OVERVIEW.: 282 (1997) (0)
- Complement factor H Y402H functional polymorphismin patients with ischemic stroke (2010) (0)
- cardiac function in postinfarcted rats Transplantation of embryonic stem cells improves (2015) (0)
- Antibody and complement-mediated glial response and demyelination (2015) (0)
- Members of the Special Advisory Commission on Mandated Health Insurance Benefits (2008) (0)
- Behavioral Health Care Subcommittee (2011) (0)
- Members in Attendance Senator George L. Barker Delegate Robert H. Brink (2008) (0)
- Members in Attendance Senator George L. Barker Delegate David L. Bulova Senator Linda T. Puller Delegate Robert H. Brink (2008) (0)
- Overview of Agenda and Letter from Virginia Disability Commission (2012) (0)
- Cancer Immunotherapy In Vitro via Multiple Sensitizes Tumor Cells to Antibody-Based Targeting Neural-Restrictive Silencer Factor (2010) (0)
- Healthy Living/Health Services Subcommittee Joint Commission on Health Care (2009) (0)
- Macular Degeneration Mouse Model of Wet-Type Age-Related Controls Choroidal Neovascularization in a CD 59 , a Complement Regulatory Protein , (2007) (0)
- Clinical and immunological correlates in myasthenia gravis associated with musk antibodies (2008) (0)
- Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23 angstrom resolution (2008) (0)
- Effects of freezer storage time on levels of complement biomarkers (2017) (0)
- Identification of mutations in rat CD59 that increase the complement regulatory activity. (2000) (0)
- Microglia changes in rat dorsal cochlear nucleus correlate to behavioural tinnitus evidence (2015) (0)
- Peptides derived from neuron-restrictive silencer factor modulate expression of CD59 and antibody-mediated complement cytotoxicity in neuroblastoma (2007) (0)
- Nephritic for Therapy of Renal Disease Associated with Alternative Pathway Convertase: Potential A Humanized Antibody That Regulates the (2014) (0)
- This information is current as Associated with Acute Axonal Injury Complement Causes Severe Demyelination The Membrane Attack Complex of Lassmann and (2001) (0)
- Competition with Cellular Receptors Affinities, Altered Particle Formation, and Soluble Forms of Its Receptors: Binding Inhibition of Coxsackie B Virus Infection by (2014) (0)
- Prognostic significance of membrane cofactor protein (CD46) on breast tumors. (2004) (0)
- Analysis of the domains in C6, C7, C8 and C9 by FT-IR spectroscopy, scattering and molecular graphics (1993) (0)
- USE OF POLYCLONAL AND MONOCLONAL ANTIBODIES IN STUDYING COMPLEMENT COMPONENT C9 AS A TRANS-MEMBRANE PROTEIN (1985) (0)
- Distribution of decay accelerating factor (DAF/CD55) on pig cells and tissues (2000) (0)
- The mechanism of C1q-mediated exacerbation of hypoxic-ischemic brain injury in neonatal mice (2007) (0)
- Molecular cloning and tissue expression of the phagocytic complement C1q receptor in rat (2000) (0)
- DAF deficiency is protective during atherosclerosis in apoE deficient mice (2010) (0)
- The Role of Complement in Experimental Autoimmune Uveoretinitis (2007) (0)
- Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease (2020) (0)
- CD59 an unexpected protective role in bone [Abstract] (2011) (0)
- The Central Nervous System (CNS) is an Extra-Hepatic Site for the Synthesis of all the Components of Complement (1994) (0)
- Exploring the effects of non-lethal complement membrane attack on CT26 Colon Carcinoma cells using network analysis of differentially expressed genes (2014) (0)
- Identification and functional characterisation of a relatively frequent CFH haplotype carrying two polymorphisms (S890I and V1007L) associated with aHUS (2008) (0)
- with Complement Activation Nervous System Inflammation Associated Chronic but Not Acute Autoimmune Central Expressed by Neurons in Response to Decay-Accelerating Factor (CD55) Is (2005) (0)
- Efficacy of an experimental gonococcal lipooligosaccharide mimitope vaccine requires terminal complement. (2021) (0)
- The crystal structure of rat complement receptor 1-related protein Y (CrrY) helps dissecting decay-acceleration and fI-cofactor activities (2008) (0)
- Complement Regulator Factor H is a Cofactor for Thrombin in both Pro- and Anticoagulant Roles (2021) (0)
- Novel monoclonal antibodies specific for the Y402 and H402 variants of complement factor H: Tools for risk prediction in AMD and for separation of alleles in other pathologies (2008) (0)
- A shRNA mediated knockdown approach to understand the role of CD59 in regulation of human CD4+ T cells (2007) (0)
- Antibody-independent classical pathway activation by CMV-infected fibroblasts (1998) (0)
- 1Complement activation and cerebral injury following ischemic stroke (2010) (0)
- Zymosan, but not LPS, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model initiated by mechanical scraping (2008) (0)
- Human Decay-Accelerating Factor (CD55) Characterization of the Rat Analogue of Molecular Cloning and Functional (1998) (0)
- Complement-Mediated Plasma-Membrane Damage: Effects on Cell Physiology, Prospects of Cell Recovery and Implications for Disease Mechanisms (1987) (0)
- Correction to: Complement in the pathogenesis of Alzheimer’s disease (2018) (0)
- Complement activity and regulation in preeclampsia (2016) (0)
- Complement as a Mediator of Inflammation (2018) (0)
- Echovirus and coxsackie B viruses that bind human CD55 are unable to use porcine CD55 as a receptor (2000) (0)
- Complement in the pathogenesis of Alzheimer’s disease (2017) (0)
- Complement evasion by Neisseria meningitidis (2011) (0)
- Complement system activation contributes to the ependymal damage induced by microbial neuraminidase (2016) (0)
- Enzymatic cleavable reagents for the specific targeting of disease herds (2002) (0)
- Activation of human synoviocytes by sub-lytic complement attack (1989) (0)
- Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99] (2013) (0)
- vasculature of healthy mice -dependent iNOS expression in the γ suppressing bacteria and IFN Circulating neutrophils maintain physiological blood pressure by (2013) (0)
- New reagents for the study of perforin synthesis storage and processing. (1998) (0)
- Regulation ofCD59expression on K562cells: effects ofphorbolmyristate acetate, cross-linking antibody andnon-lethal complementattack (1995) (0)
- Correction to: Role of complement and potential of complement inhibitors in myasthenia gravis and neuromyelitis optica spectrum disorders: a brief review (2021) (0)
- Cross-linking of the glycosyl phosphatidylinositol-anchored complement inhibitors CD59 and CD55 on neutrophils triggers cell activation via tyrosine kinase (1993) (0)
- In vivo characterisation and therapeutic efficacy of a C5-specific inhibitor [Abstract] (2007) (0)
- COMPLEMENT ACTIVATION IN MULTIPLE SCLEROSIS AND NMO SPECTRUM DISORDERS (2016) (0)
- MBL serum levels and MBL2 genotypes in South African patients with complete complement C6 deficiency (C6Q0) with or without a history of Neisseria meningitidis infections (2007) (0)
- Characterization invitro andinvivo ofthepiganalogue ofhumanCD59using new monoclonal antibodies (1998) (0)
- Bi-specific monoclonal antibodies directed against CD55 and a cell-surface antigen and their effect on human renal tumor cells (1997) (0)
- Complement system biomarkers in demyelinating disease (2016) (0)
- Transcriptional control of expression of complement regulators in tumour cells: Peptide inhibition of a transcription enhancer reduces expression of multiple regulators (2009) (0)
- Protection of hepatoma cells from complement attack mediated by cytokine upregulation of DAF and CD59 (1998) (0)
- Regulation of expression of CD59 via interplay between REST and nucleolin transcription factors; implications for cancer immunotherapy (2009) (0)
- Complement activation associated to ischaemia and reperfusion in clinical renal transplantation (2007) (0)
- Expression of recombinant human perforin in eukaryotic cells (1993) (0)
- IgG subclasses of disease-specific antibodies and complement activation in vitro in myasthenia gravis and neuromyelitis optica (2007) (0)
- Complement-Independent Manner T Cell Activity in a + Antiviral CD 4 Cutting Edge : Murine CD 59 a Modulates (2005) (0)
- Terminal complement pathway activation and neuroaxonal damage in a mouse model of traumatic brain injury (2011) (0)
- Relevance to Xenotransplantation Characterization of the Pig Analogue of CD 59 : Molecular Cloning and Functional (1998) (0)
- Cloning of rat DAF: Two forms on a single gene (1998) (0)
- Correction to: Role of complement and potential of complement inhibitors in myasthenia gravis and neuromyelitis optica spectrum disorders: a brief review (2019) (0)
- Mechanism of induction of haemolysis by Loxosceles intermedia spider venom (1998) (0)
- Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma (2016) (0)
- Cellular expression and organ distribution of the pig analog of membrane cofactor protein MCP (CD46) (1998) (0)
- Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation (2022) (0)
- CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers (2018) (0)
- Structure of the N-terminal four domains of the complement regulator Rat Crry (2011) (0)
- Complement mediated inflammation contributes to neuronal cell loss and gliosis in Huntington's disease (1998) (0)
- Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage (2019) (0)
- Chapter 10 Activation and control of the complement system (1996) (0)
- Generation of anti-complement prodrugs for specific delivery of active regulator to disease sites (2002) (0)
- Time Dependent Association of Exogenous GPI-Anchored CD59 into High Molecular Weight Kinase Containing Complexes in a CD59 Negative Cell Line (1994) (0)
- Absence of CD59a leads to exacerbated neuroinflammation and neuropathology after experimental closed head injury in mice (2007) (0)
- Production and functional characterisation of a soluble recombinant form of mouse CD59 (1998) (0)
- MouseAttack Complex Assembly in the CD59a Is the Primary Regulator of (2013) (0)
- Molecular and functional analysis of alternatively spliced forms of mouse decay accelerating factor (CD55) (1998) (0)
- Development of complement regulator expressing adenoviral vectors for use in gene therapy of experimental arthritis (1998) (0)
- Sensitive and specific assays for C3 nephritic factors permit dissection of mechanisms underlying complement dysregulation (2010) (0)
- The aHUS-associated BF mutations F286L and K323E stabilise the alternative pathway C3 convertase (2007) (0)
- C3-dependent microglial priming caused by deletion of the membrane complement regulator Crry (2010) (0)
- Phagocytosis of Apoptotic Neutrophils by Glucocorticoids Induce Protein S-Dependent (2009) (0)
- Surface plasmon resonance analysis of decay acceleration in the alternative pathway of complement (2007) (0)
- Complement dysregulation and Alzheimer's disease in Down syndrome (2022) (0)
- The choroid plexus as a depository for the innate and humoural adaptive immune systems (2014) (0)
- The CCP6-8 and CCP19-20 ‘heparin’-binding regions of complement factor H have different and tissue-specific glycosaminoglycan-binding properties (2011) (0)
- Complement receptor 1 is expressed on brain cells and in the human brain (2023) (0)
- Hexamerization-enhanced CD 20 antibody mediates complement-dependent cytotoxicity in serum genetically de fi cient in C 9 (2017) (0)
- Complement and multiple sclerosis (1988) (0)
- Local therapy with soluble complement receptor 1 (sCR1) suppresses inflammation in rat mono‐articular arthritis (1997) (0)
- Tissue distribution of complement regulatory proteins in rat gastrointestinal tracts (1995) (0)
- Activation in a Rat Peritonitis Model Injury Accompanied by Complement Triggers Severe and Progressive Peritoneal Zymosan, but Not Lipopolysaccharide, (2009) (0)
- Monoclonal antibodies and the structure of complement component C9 (1985) (0)
- Crry deficiency switches the resting microglial phenotype to the primedstate (2009) (0)
- Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and factor H-C3b complex (2020) (0)
- High resolution structure of human CD59 (2007) (0)
- CD59A - a novel regulator of bone turnover in mice (2010) (0)
- A role for complement in demyelination: A review of evidence from cells, experimental animals and patients (1994) (0)
- Selection of phage-displayed peptides to human CD55: therapeutic applications in the control of complement activation in disease (2002) (0)
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What Schools Are Affiliated With Bryan Paul Morgan?
Bryan Paul Morgan is affiliated with the following schools:
