Bryant Villeponteau
American scientist, entrepreneur, and longevity expert
Bryant Villeponteau's AcademicInfluence.com Rankings

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Biology
Bryant Villeponteau's Degrees
- PhD Molecular Biology Stanford University
- Masters Biochemistry University of California, Berkeley
Why Is Bryant Villeponteau Influential?
(Suggest an Edit or Addition)According to Wikipedia, Bryant Villeponteau is an American scientist, entrepreneur, and longevity expert who has worked in both academia and industry. His early work included the cloning of the RNA component of human telomerase when working at Geron Corporation, which led to his winning the 1997 Distinguished Inventor Award for cloning human telomerase along with three of his Geron teammates. In 2008, Villeponteau went on to serve as Vice President of Research of the aging genetics company Genescient, Inc., which uses machine learning technologies, biochemistry, and Drosophila genetics to develop therapeutics to help delay the aging process. He is also a cofounder of Centagen, Inc., which focuses on developing new technologies for extending human health and longevity by promoting adult stem cells.
Bryant Villeponteau's Published Works
Published Works
- Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. (1996) (461)
- Functional characterization and developmental regulation of mouse telomerase RNA (1995) (380)
- Telomeres and telomerase in aging and cancer. (1995) (291)
- Cataloging altered gene expression in young and senescent cells using enhanced differential display. (1995) (236)
- The heterochromatin loss model of aging (1997) (192)
- Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation (1998) (181)
- Torsional stress promotes the DNAase I sensitivity of active genes (1984) (113)
- Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells. (1997) (83)
- Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viability (1997) (76)
- Similar gene expression pattern in senescent and hyperoxic-treated fibroblasts. (1998) (72)
- Effect of replicative age on transcriptional silencing near telomeres in Saccharomyces cerevisiae. (1996) (71)
- Models of in vitro angiogenesis: endothelial cell differentiation on fibrin but not matrigel is transcriptionally dependent. (1995) (69)
- An altered repertoire of fos/jun (AP-1) at the onset of replicative senescence. (1992) (68)
- Suppression of PCR amplification by high levels of RNA. (1993) (62)
- A 5' beta-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription. (1994) (59)
- The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence. (1998) (43)
- Serum stimulation of the c-fos enhancer induces reversible changes in c-fos chromatin structure (1990) (40)
- Hemoglobin switching in chickens. Is the switch initiated post-transcriptionally? (1982) (39)
- Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of beta-globin gene chromatin in vivo (1987) (37)
- Cloning and expression of SAG: a novel marker of cellular senescence. (1992) (35)
- Heparin increases chromatin accessibility by binding the trypsin-sensitive basic residues in histones. (1992) (34)
- The polyomavirus enhancer activates chromatin accessibility on integration into the HPRT gene (1992) (28)
- High-resolution analysis of c-fos chromatin accessibility using a novel DNase I-PCR assay. (1992) (27)
- The chicken beta globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats. (1982) (25)
- Nutraceutical interventions may delay aging and the age-related diseases (2000) (25)
- Isolation and characterization of the complete chicken β-globin gene region: frequent deletion of the adult β-globin genes in λ (1981) (21)
- Novobiocin induces the in vivo cleavage of active gene sequences in intact cells. (1986) (21)
- Nucleosome spacing is compressed in active chromatin domains of chick erythroid cells. (1992) (19)
- Long-Term Functional Side-Effects of Stimulants and Sedatives in Drosophila melanogaster (2009) (19)
- Genome-wide analysis of long-term evolutionary domestication in Drosophila melanogaster (2015) (17)
- Active beta-globin gene transcription occurs in methylated, DNase I-resistant chromatin of nonerythroid chicken cells (1990) (15)
- Long-term growth of diploid human fibroblasts in low serum media (1990) (15)
- Herbal Supplement Extends Life Span Under Some Environmental Conditions and Boosts Stress Resistance (2015) (10)
- Incorporation of nuclear matrix attachment regions into the herpes simplex virus type 1 genome does not induce long-term expression of a foreign gene during latency. (1996) (7)
- Proliferative capacity of human fibroblasts when cultured in serum from young or old cows. (1989) (7)
- A phosphatase inhibitor enhances the DNase I sensitivity of active chromatin. (1991) (6)
- The RNA components of human and mouse telomerases (1996) (4)
- Decline in histone H5 phosphorylation during erythroid senescence in chick embryos (1991) (4)
- Isolation and characterization of the complete chicken beta-globin gene region: frequent deletion of the adult beta-globin genes in lambda. (1981) (4)
- Similar Gene Expression Patterns in Senescent and Hyperoxically Blocked Fibroblasts (1998) (2)
- Multipath Natural Product Supplement Suppresses Dementia Symptoms in Amyloid-β and Tau Transgenic Drosophila (2018) (1)
- Nutritional Approaches to Reducing Oxidative Stress (2002) (1)
- Telomere loss, telomerase, and cancer (1995) (1)
- Characterization of a topoisomerase-like activity at specific hypersensitive sites in the Drosophila histone gene cluster. (1989) (1)
- Treating multiple antiaging pathways improves health markers in open label clinical study (2017) (1)
- Dosages de regulateurs de l'expression d'une telomerase mammalienne (1997) (0)
- ThePolyomavirus Enhancer Activates Chromatin Accessibility onIntegration into theHPRT Gene (1992) (0)
- The RNA Component of Human Telomerase Author ( s ) : (2008) (0)
- United States Patent 19 Villeponteau et al . 54 ASSAYS FOR THE DNACOMPONENT OF HUMAN TELOMERASE 75 Inventors : (2017) (0)
- ltered Repertoire of fos / jun ( A of Replicative Senescent (0)
- Botanical Mixture Stabilizes Cognitive Function in Patients with Mild and Moderate Alzheimerâs Disease (2018) (0)
- Multipath Herbal Nutraceutical Improves Self-Reported Markers of Health and Life Expectancy in Clinical Study (2018) (0)
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