Colin C. F. Blake
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Most Influential Person Now
Colin C. F. Blake's AcademicInfluence.com Rankings
Colin C. F. Blakephysics Degrees
Physics
#7018
World Rank
#9018
Historical Rank
Biophysics
#298
World Rank
#310
Historical Rank
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Chemistry Physics
Colin C. F. Blake's Degrees
- PhD Biophysics University of Oxford
- Bachelors Chemistry University of Oxford
Why Is Colin C. F. Blake Influential?
(Suggest an Edit or Addition)Colin C. F. Blake's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Common core structure of amyloid fibrils by synchrotron X-ray diffraction. (1997) (1567)
- Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis (1997) (984)
- The structure of amyloid fibrils by electron microscopy and X-ray diffraction. (1997) (726)
- Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A. (1977) (701)
- Human lysozyme gene mutations cause hereditary systemic amyloidosis (1993) (582)
- Crystallographic studies of the activity of hen egg-white lysozyme (1967) (539)
- From the globular to the fibrous state: protein structure and structural conversion in amyloid formation (1998) (398)
- Sequence, structure and activity of phosphoglycerate kinase: a possible hinge-bending enzyme (1979) (396)
- Crystallographic studies of the dynamic properties of lysozyme (1979) (375)
- On the conformation of the hen egg-white lysozyme molecule (1967) (337)
- Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix (1996) (336)
- Do genes-in-pieces imply proteins-in-pieces? (1978) (263)
- Strjcture of human plasma prealbumin at 2-5 A resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding. (1974) (249)
- Refinement of human lysozyme at 1.5 A resolution analysis of non-bonded and hydrogen-bond interactions. (1981) (239)
- Iron‐ and manganese‐containing superoxide dismutases can be distinguished by analysis of their primary structures (1988) (220)
- Protein–DNA and protein–hormone interactions in prealbumin: a model of the thyroid hormone nuclear receptor? (1977) (195)
- The refined structure of the quinoprotein methanol dehydrogenase from Methylobacterium extorquens at 1.94 A. (1995) (181)
- The molecular basis of amyloidosis (1997) (162)
- Amyloid Precursor Protein (2002) (157)
- X-ray studies of water in crystals of lysozyme. (1983) (153)
- Structure of horse muscle phosphoglycerate kinase. Some results on the chain conformation, substrate binding and evolution of the molecule from a 3 angstrom Fourier map. (1974) (151)
- Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution. (1965) (151)
- Molecular Structure of a Fibrillar Alzheimer's Aβ Fragment† (2000) (147)
- Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs. (1995) (143)
- Structurally specific binding of halogenated biphenyls to thyroxine transport protein. (1986) (137)
- The Structures of the Monoclinic and Orthorhombic Forms of Hen Egg-White Lysozyme at 6 Angstroms Resolution (1981) (125)
- Crystal structure of manganese superoxide dismutase from Bacillus stearothermophilus at 2.4 A resolution. (1988) (118)
- Molecular mechanics simulation of protein-ligand interactions: binding of thyroid hormone analogs to prealbumin (1982) (110)
- Molecular biology: Exons — present from the beginning? (1983) (108)
- Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain. (1985) (105)
- The structure and function of methanol dehydrogenase and related quinoproteins containing pyrrolo-quinoline quinone. (1994) (103)
- An x-ray study of the subunit structure of prealbumin. (1971) (102)
- Structure of Met30 variant of transthyretin and its amyloidogenic implications. (1993) (97)
- The active site of methanol dehydrogenase contains a disulphide bridge between adjacent cysteine residues (1994) (89)
- Exons encode protein functional units (1979) (82)
- Structure Of Lysozyme: A Fourier Map of the Electron Density at 6 Å Resolution obtained by X-ray Diffraction (1962) (79)
- Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin. (1985) (78)
- Computer graphics in drug design: molecular modeling of thyroid hormone-prealbumin interactions. (1982) (77)
- The crystal structure of benzamide (1972) (72)
- X-ray analysis of structure of human lysozyme at 6 A resolution. (1971) (66)
- Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous beta-sheet helix. (1996) (64)
- Exons and the evolution of proteins. (1985) (61)
- The crystal structure of transthyretin from chicken. (1996) (59)
- Molecular structure of a fibrillar Alzheimer's A beta fragment. (2000) (49)
- Structure of Horse-muscle Phosphoglycerate Kinase at 6 Å Resolution (1972) (48)
- Phosphoglycerate kinase. (1981) (48)
- Structural identity between the iron- and manganese-containing superoxide dismutases. (1987) (46)
- A molecular model of the amyloid fibril. (1996) (45)
- An x-ray study of the structure and binding properties of iodine-inactivated lysozyme. (1975) (44)
- The "edge strand" hypothesis: Prediction and test of a mutational "hot-spot" on the transthyretin molecule associated with FAP amyloidogenesis (1996) (40)
- The preparation of isomorphous derivatives. (1968) (38)
- Genes pieced together — exons delineate homologous structures of diverged lysozymes (1981) (37)
- The compact domain conformation of human Glu-plasminogen in solution. (1992) (37)
- Structure and binding properties of hen lysozyme modified at tryptophan 62. (1981) (34)
- Proteins, exons and molecular evolution. (1987) (32)
- S-S bridges of cathepsin B and H from bovine spleen: a basis for cathepsin B model building and possible functional implications for discrimination between exo- and endopeptidase activities among cathepsins B, H and L. (1991) (30)
- Crystallographic study of the interaction of urea with lysozyme (1974) (30)
- Exons--present from the beginning? (1983) (29)
- Exons and the structure, function and evolution of haemoglobin (1981) (29)
- A crystallographic study of the oxidation of lysozyme by iodine (1967) (26)
- Exons and the evolution of proteins (1983) (26)
- A "helix-scissors" mechanism for the hinge-bending conformational change in phosphoglycerate kinase. (2009) (24)
- X-ray analysis of thyroid hormone binding to prealbumin. (1978) (24)
- Comparison of the modelled thyroxine binding site in TBG with the experimentally determined site in transthyretin. (1992) (22)
- Deriving the generic structure of the fibronectin type II domain from the prothrombin Kringle 1 crystal structure. (1987) (21)
- Molecular mechanisms of fibrillogenesis and the protective role of amyloid P component: two possible avenues for therapy. (1996) (20)
- Structure and order of the protein and carbohydrate domains of prothrombin fragment 1 (1987) (19)
- Preliminary crystallographic data on human lysozyme. (1969) (18)
- Exon and domain evolution in the proenzymes of blood coagulation and fibrinolysis. (1987) (15)
- The crystal structure of tortoise egg-white lysozyme at 6 A resolution. (1980) (15)
- Preliminary X-ray investigation of enzyme substrate complexes of horse muscle phosphoglycerate kinase. (1984) (15)
- Review Lecture - Prealbumin and the thyroid hormone nuclear receptor (1981) (15)
- Phosphotransfer hinges in PGK (1997) (13)
- X-ray structure of PQQ-dependent methanol dehydrogenase. (1994) (13)
- Physical and chemical properties of lysozyme. (1977) (13)
- Tail-wagging antibodies? (1976) (12)
- 6 – The High Resolution X-Ray Study of Human Lysozyme: A Preliminary Analysis (1974) (11)
- The enzymes of glycolysis: structure, activity and evolution. (1981) (10)
- Crystallization and preliminary crystallographic study of cathepsin D inhibitor from potatoes. (1991) (9)
- X‐ray enzymology (1976) (8)
- How the structure of lysozyme was actually determined (2006) (8)
- Structure of lysozyme. A Fourier map of the electron density at 6 angstrom resolution obtained by x-ray diffraction. (1962) (7)
- Evolution of nucleotide-binding proteins (1974) (7)
- Prealbumin and the thyroid hormone nuclear receptor. (1981) (7)
- Crystallization and preliminary crystallographic investigation of methanol dehydrogenase from Methylobacterium extorquens AM1. (1992) (6)
- The trouble with kinase crystals (1978) (5)
- Comparison of X-ray data to estimated secondary structures from amino acid sequence and circular dichroism of human prealbumin (1976) (5)
- X-ray studies of crystalline proteins. (1972) (5)
- X-ray cryoenzymology (1976) (4)
- Antibody structure and antigen binding (1975) (4)
- The nucleotide-binding fold revisited (1977) (4)
- An explanation for the efficacy of attack by platinum blue drugs on biopolymers (1976) (3)
- Structure of horse-muscle phosphoglycerate kinase at 6 angstrom resolution. (1972) (3)
- Structure and control of phosphorylase (1979) (3)
- Predicting a membrane protein (1980) (3)
- Erratum: The active site of methanol dehydrogenase contains a disulphide bridge between adjacent cysteine residues (1994) (3)
- X-RAY CRYSTALLOGRAPHIC STUDIES OF THYROID HORMONE, ANALOGUE AND COMPETITOR BINDING INTERACTIONS WITH HUMAN SERUM PREALBUMIN (1982) (2)
- MOLECULAR INTERACTIONS OF TOXIC CHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS WITH THYROXINE BINDING PREALBUMIN (1985) (2)
- The crystal structure of manganese superoxide dismutase from Bacillus stearothermophilus (1987) (2)
- Crystalline cis-benzene glycol dehydrogenase from Pseudomonas putida. (1977) (2)
- Analysis of the structure at 2 Å resolution (2012) (1)
- Structure of a lectin: Crystallographic results (1975) (1)
- The Structure and Function of Lysozyme (1969) (1)
- Studies on the Molecular Arrangement in Transthyretin-Related Familial Amyloidotic Polyneuropathy Fibrils (1991) (1)
- Molecular Mechanisms of Amyloid Fibril Formation: The Lysozyme Model (1996) (1)
- Obituary: David Chilton Phillips (Lord Phillips of Ellesmere), 1924–1999 (1999) (1)
- X-ray analysis of protein dynamics (1979) (1)
- Multi-Domain Proteins: Towards Complete Structures (1989) (1)
- X-ray sequencing of proteins by refinement (1978) (1)
- A Laboratory Method for Studying the Kinetics of Bleach-Fixing in Colour Processes (1975) (1)
- The structure of benzamide (1959) (1)
- Interpreting protein electron density maps (1976) (0)
- Reviews Exons and the evolution of proteins (1983) (0)
- AMYLOIDOGENIC VARIANT (I56T) VARIANT OF HUMAN LYSOZYME (1997) (0)
- Methylobacterium extorquens methanol dehydrogenase (2001) (0)
- Book Review:Lysozyme. Elliott F. Osserman, Robert E. Canfield, Sherman Beychok (1976) (0)
- The fifteenth Douglas Lea lecture: X-ray studies of protein-DNA-hormone interactions. (1978) (0)
- All you need to know about proteins (1980) (0)
- Towards some enzyme mechanisms (1977) (0)
- Protein crystal chemistry (1969) (0)
- X-ray analysis of an unusual reaction in lysozyme. (1970) (0)
- The crystal structure of a bifunctional Kunitz type cysteine proteinase inhibitor at 1.9 Å resolution (1996) (0)
- Introducing cryobiochemistry (1977) (0)
- The High-Resolution Structure of Horse Phosphoglycerate Kinase (1974) (0)
- An x-ray study of the product of an unusual reaction in lysozyme. (1970) (0)
- The molecular structure of the FAP fibril (1996) (0)
- Macromolecules in 3D (1980) (0)
- AMYLOIDOGENIC VARIANT (ASP67HIS) OF HUMAN LYSOZYME (1997) (0)
- X-ray studies of glycolytic enzymes. (1975) (0)
- Chemical aspects of protein crystallography. (1975) (0)
- The first structure of an avian transthyretin : Similarities and differences shown by the human and chicken proteins (1996) (0)
- COMPUTER GRAPHICS IN DRUG DESIGN: MOLECULAR MODELING OF THYROID HORMONE-PREALBUMIN INTERACTIONS (1982) (0)
- THE USE OF PHASE COMBINATION IN THE REFINEMENT OF PHOSPHOGLYCERATE KINASE AT 2.5 ANGSTROMS RESOLUTION (1976) (0)
- Thyroid hormone interactions with prealbumin (1981) (0)
- Towards the design of non‐amyloidogenic proteins (2007) (0)
- Science and art of biomolecules (1995) (0)
- Immunoglobulin surprises (1975) (0)
- Part III: X-Ray analysis (1969) (0)
- TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN) (1996) (0)
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