C. Cliffton Ling
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Medical Physics
Why Is C. Cliffton Ling Influential?
(Suggest an Edit or Addition)C. Cliffton Ling's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality. (2000) (946)
- High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients. (2002) (831)
- High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancer. (2001) (726)
- Deep inspiration breath-hold technique for lung tumors: the potential value of target immobilization and reduced lung density in dose escalation. (1999) (622)
- DOSE ESCALATION WITH THREE-DIMENSIONAL CONFORMAL RADIATION THERAPY AFFECTS THE OUTCOME IN PROSTATE CANCER (1998) (616)
- Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer. (2000) (565)
- Radiation-induced apoptosis: relevance to radiotherapy. (1995) (499)
- Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy. (1998) (456)
- Effect of respiratory gating on quantifying PET images of lung cancer. (2002) (439)
- Respiration-correlated spiral CT: a method of measuring respiratory-induced anatomic motion for radiation treatment planning. (2002) (433)
- The deep inspiration breath-hold technique in the treatment of inoperable non-small-cell lung cancer. (2000) (403)
- Conformal radiation treatment of prostate cancer using inversely-planned intensity-modulated photon beams produced with dynamic multileaf collimation. (1996) (387)
- Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer. (1999) (379)
- Late rectal bleeding after conformal radiotherapy of prostate cancer. II. Volume effects and dose-volume histograms. (2001) (356)
- Late rectal toxicity after conformal radiotherapy of prostate cancer (I): multivariate analysis and dose-response. (2000) (328)
- Planning, delivery, and quality assurance of intensity-modulated radiotherapy using dynamic multileaf collimator: a strategy for large-scale implementation for the treatment of carcinoma of the prostate. (1997) (321)
- Number and orientations of beams in intensity-modulated radiation treatments. (1997) (317)
- Technical aspects of the deep inspiration breath-hold technique in the treatment of thoracic cancer. (2000) (311)
- Treatment planning and delivery of intensity-modulated radiation therapy for primary nasopharynx cancer. (2001) (304)
- Clinically relevant optimization of 3-D conformal treatments. (1992) (297)
- Effect of respiratory gating on reducing lung motion artifacts in PET imaging of lung cancer. (2002) (296)
- Dose-volume factors contributing to the incidence of radiation pneumonitis in non-small-cell lung cancer patients treated with three-dimensional conformal radiation therapy. (2002) (295)
- Commissioning and quality assurance of RapidArc radiotherapy delivery system. (2008) (294)
- Evaluation of respiratory movement during gated radiotherapy using film and electronic portal imaging. (2002) (286)
- Measurement of lung tumor motion using respiration-correlated CT. (2004) (271)
- Quantification and predictors of prostate position variability in 50 patients evaluated with multiple CT scans during conformal radiotherapy. (1999) (248)
- Fluoroscopic evaluation of diaphragmatic motion reduction with a respiratory gated radiotherapy system (2001) (247)
- Correlation of dosimetric factors and radiation pneumonitis for non-small-cell lung cancer patients in a recently completed dose escalation study. (2004) (245)
- Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. (1998) (242)
- Fluorine-18-labeled fluoromisonidazole positron emission and computed tomography-guided intensity-modulated radiotherapy for head and neck cancer: a feasibility study. (2008) (235)
- Reproducibility of intratumor distribution of (18)F-fluoromisonidazole in head and neck cancer. (2008) (226)
- Comparison of the 5-Year Outcome and Morbidity of Three-Dimensional Conformal Radiotherapy Versus Transperineal Permanent Iodine-125 Implantation for Early-Stage Prostatic Cancer (1999) (216)
- Comprehensive quality assurance for the delivery of intensity modulated radiotherapy with a multileaf collimator used in the dynamic mode. (2001) (215)
- AAPM code of practice for radiotherapy accelerators: report of AAPM Radiation Therapy Task Group No. 45. (1994) (209)
- Synergistic effect of the v-myc oncogene with H-ras on radioresistance. (1990) (194)
- Results of a phase I dose‐escalation study using three‐dimensional conformal radiotherapy in the treatment of inoperable nonsmall cell lung carcinoma (2005) (188)
- Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor mo (2005) (188)
- Dependence of FDG uptake on tumor microenvironment. (2005) (184)
- A patient-specific respiratory model of anatomical motion for radiation treatment planning. (2007) (176)
- The influence of changes in tumor hypoxia on dose-painting treatment plans based on 18F-FMISO positron emission tomography. (2008) (174)
- Hypoxia-Induced increase in FDG uptake in MCF7 cells. (2001) (160)
- The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest. (2000) (157)
- Permanent implants using Au-198, Pd-103 and I-125: radiobiological considerations based on the linear quadratic model. (1992) (157)
- Improved local control with higher doses of radiation in large-volume stage III non-small-cell lung cancer. (2004) (155)
- Intensity-modulated radiotherapy. (2002) (154)
- The role of the H-ras oncogene in radiation resistance and metastasis. (1990) (144)
- The biological basis for conformal three-dimensional radiation therapy. (1991) (143)
- Delivery of intensity-modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods. (2001) (139)
- Improved dose distributions for 3D conformal boost treatments in carcinoma of the nasopharynx. (1991) (132)
- CT-assisted assessment of bladder and rectum dose in gynecological implants. (1987) (128)
- The use of a multi-leaf collimator for conformal radiotherapy of carcinomas of the prostate and nasopharynx. (1993) (128)
- Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia. (2009) (127)
- Radioresistance induced by oncogenic transformation. (1989) (125)
- Optimization of intensity-modulated 3D conformal treatment plans based on biological indices. (1995) (123)
- Probability of radiation-induced complications in normal tissues with parallel architecture under conditions of uniform whole or partial organ irradiation. (1993) (123)
- The potential and limitations of the inverse radiotherapy technique. (1994) (120)
- Visualization of hypoxia in microscopic tumors by immunofluorescent microscopy. (2007) (120)
- Physical Aspects of Quality Assurance in Radiation Therapy (1984) (119)
- Prospective trial incorporating pre-/mid-treatment [18F]-misonidazole positron emission tomography for head-and-neck cancer patients undergoing concurrent chemoradiotherapy. (2009) (118)
- IMRT of large fields: whole-abdomen irradiation. (2001) (118)
- A CT-based evaluation method for permanent implants: application to prostate. (1993) (114)
- Dose-rate effects in external beam radiotherapy redux. (2010) (109)
- Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM. (2005) (107)
- The relative biological effectiveness of I-125 and Pd-103. (1995) (106)
- Thermal enhancement of melphalan and oxaliplatin cytotoxicity in vitro (2002) (105)
- Physical dosimetry of 125I seeds of a new design for interstitial implant. (1983) (101)
- Relative profile and dose verification of intensity-modulated radiation therapy. (2000) (98)
- Electrons as the cause of the observed dmax shift with field size in high energy photon beams. (1979) (97)
- Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning (2003) (96)
- The biological basis and clinical application of three-dimensional conformal external beam radiation therapy in carcinoma of the prostate. (1994) (96)
- Apoptosis in heat-induced cell killing: the protective role of hsp-70 and the sensitization effect of the c-myc gene. (1996) (95)
- Risk group dependence of dose-response for biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer. (2002) (94)
- Cone-beam CT with megavoltage beams and an amorphous silicon electronic portal imaging device: potential for verification of radiotherapy of lung cancer. (2002) (92)
- Intensity-modulated radiotherapy versus conventional three-dimensional conformal radiotherapy for boost or salvage treatment of nasopharyngeal carcinoma. (2002) (89)
- Fitting tumor control probability models to biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer: pitfalls in deducing radiobiologic parameters for tumors from clinical data. (2001) (88)
- From IMRT to IGRT: frontierland or neverland? (2006) (88)
- Technological advances in external-beam radiation therapy for the treatment of localized prostate cancer. (2003) (87)
- Using computerized video time lapse for quantifying cell death of X-irradiated rat embryo cells transfected with c-myc or c-Ha-ras. (1999) (86)
- Modeling the development of metastases from primary and locally recurrent tumors: comparison with a clinical data base for prostatic cancer. (1993) (82)
- Two-dimensional dose distribution of 125I seeds. (1985) (81)
- Predictors of improved outcome for patients with localized prostate cancer treated with neoadjuvant androgen ablation therapy and three-dimensional conformal radiotherapy. (1998) (80)
- Final report of the 70.2-Gy and 75.6-Gy dose levels of a phase I dose escalation study using three-dimensional conformal radiotherapy in the treatment of inoperable non-small cell lung cancer. (2000) (80)
- Oxygen depletion in cells irradiated at ultra-high dose-rates and at conventional dose-rates. (1974) (80)
- Smoothing intensity-modulated beam profiles to improve the efficiency of delivery. (2001) (79)
- The feasibility of dose escalation with three-dimensional conformal radiotherapy in patients with prostatic carcinoma. (1995) (79)
- Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo. (2003) (78)
- Reduction of organ motion in lung tumors with respiratory gating. (2006) (77)
- The variation of OER with dose rate. (1985) (75)
- Oxygen sensitization of CHO cells at ultrahigh dose rates: prelude to oxygen diffusion studies. (1978) (74)
- Computerized design of target margins for treatment uncertainties in conformal radiotherapy. (1999) (74)
- Comparison of tumor volumes as determined by pathologic examination and FDG-PET/CT images of non-small-cell lung cancer: a pilot study. (2009) (74)
- Locally advanced prostatic cancer: long-term toxicity outcome after three-dimensional conformal radiation therapy--a dose-escalation study. (1998) (74)
- Carcinoma of the cervix: patterns of care studies: review of 1978, 1983, and 1988-1989 surveys. (1995) (73)
- Evaluation of an automated deformable image matching method for quantifying lung motion in respiration-correlated CT images. (2006) (72)
- Comparison of intensity-modulated radiotherapy with three-dimensional conformal radiation therapy planning for glioblastoma multiforme. (2003) (70)
- Dose parameters of 125I and 192Ir seed sources. (1989) (69)
- Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry. (2008) (66)
- A stereotactic method for the three-dimensional registration of multi-modality biologic images in animals: NMR, PET, histology, and autoradiography. (2003) (65)
- Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. (2008) (65)
- Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. (1994) (63)
- Immunohistochemical detection of changes in tumor hypoxia. (2009) (62)
- Observation of interfractional variations in lung tumor position using respiratory gated and ungated megavoltage cone-beam computed tomography. (2007) (61)
- Developments in megavoltage cone beam CT with an amorphous silicon EPID: reduction of exposure and synchronization with respiratory gating. (2005) (61)
- CT-based optimized planning for transperineal prostate implant with customized template. (1991) (61)
- Oxygen sensitization of mammalian cells under different irradiation conditions. (1981) (60)
- Cell killing, radiosensitization and cell cycle redistribution induced by chronic hypoxia. (1984) (60)
- Quantifying the effect of dose inhomogeneity in brachytherapy: application to permanent prostatic implant with 125I seeds. (1994) (58)
- Using the frame averaging of aS500 EPID for IMRT verification (2003) (58)
- Dose inhomogeneity in interstitial implants using 125I seeds. (1979) (58)
- Radiation-induced apoptosis: effects of cell age and dose fractionation. (1995) (57)
- Computerized Video Time-Lapse Analysis of Apoptosis of REC:Myc Cells X-Irradiated in Different Phases of the Cell Cycle (2000) (57)
- In vivo19F Magnetic Resonance Spectroscopy and Chemical Shift Imaging of Tri-Fluoro-Nitroimidazole as a Potential Hypoxia Reporter in Solid Tumors (2007) (57)
- Specification of Brachytherapy Source Strength (1987) (56)
- Comparison of end normal inspiration and expiration for gated intensity modulated radiation therapy (IMRT) of lung cancer. (2005) (55)
- Apoptosis induced at different dose rates: implication for the shoulder region of cell survival curves. (1994) (54)
- Apoptosis induced by X-irradiation of rec-myc cells is postmitotic and not predicted by the time after irradiation or behavior of sister cells. (1996) (54)
- AAPM Code of Practice for Radiotherapy Accelerators (2000) (53)
- Evaluation of concave dose distributions created using an inverse planning system. (2002) (53)
- A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia (2004) (52)
- Integrating respiratory gating into a megavoltage cone-beam CT system. (2006) (49)
- Dosimetry, field shaping and other considerations for intra-operative electron therapy. (1981) (49)
- Acquisition of MV-scatter-free kilovoltage CBCT images during RapidArc™ or VMAT. (2011) (48)
- Improving the buildup and depth-dose characteristics of high energy photon beams by using electron filters. (1979) (47)
- An equation for the dose response of radiation-induced apoptosis: possible incorporation with the LQ model. (1994) (46)
- Comparison of the 5-year outcome and morbidity of three-dimensional conformal radiotherapy versus transperineal permanent iodine-125 implantation for early-stage prostatic cancer. (1999) (46)
- Dose distributions of model 6702 I-125 seeds in water. (1987) (46)
- Iodination of annexin V for imaging apoptosis. (2002) (45)
- Computerized tomography in radiation therapy (1983) (45)
- Magnetic analysis of the radiation components of a 10 MV photon beam. (1982) (44)
- Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts. (1999) (44)
- Optimization of conformal thoracic radiotherapy using cone-beam CT imaging for treatment verification. (2003) (43)
- Three-dimensional conformal treatment: a new frontier in radiation therapy. (1991) (43)
- An iterative EPID calibration procedure for dosimetric verification that considers the EPID scattering factor. (2001) (42)
- Development of a semi-automatic alignment tool for accelerated localization of the prostate. (2003) (42)
- Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors. (2006) (41)
- Measurements of Tumor Tissue Oxygen Tension Using a Time-Resolved Luminescence-Based Optical OxyLite Probe: Comparison with a Paired Survival Assay (2002) (41)
- Characterization of radiation-induced apoptosis in rodent cell lines. (1997) (41)
- A study of the effects of internal organ motion on dose escalation in conformal prostate treatments. (2003) (41)
- Analysis of biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer using dose-distribution variables and tumor control probability models. (2000) (40)
- Empowering Intensity Modulated Proton Therapy Through Physics and Technology: An Overview. (2017) (40)
- Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions. (2007) (40)
- Oxygen diffusion into mammalian cells following ultrahigh dose rate irradiation and lifetime estimates of oxygen-sensitive species. (1978) (39)
- Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole (2007) (38)
- High 18F-FDG Uptake in Microscopic Peritoneal Tumors Requires Physiologic Hypoxia (2010) (38)
- The effect of setup uncertainties on the radiobiological advantage of fractionation in stereotaxic radiotherapy. (1996) (37)
- On measuring hypoxia in individual tumors with radiolabeled agents. (2001) (37)
- Time trends in organ position and volume in patients receiving prostate three-dimensional conformal radiotherapy. (2002) (37)
- High-tech will improve radiotherapy of NSCLC: a hypothesis waiting to be validated. (2004) (37)
- Visualization of experimental lung and bone metastases in live nude mice by X-ray micro-computed tomography. (2006) (37)
- 18F-Fluromisonidazole PET Imaging as a Biomarker for the Response to 5,6-Dimethylxanthenone-4-Acetic Acid in Colorectal Xenograft Tumors (2011) (36)
- Imaging hypoxia in orthotopic rat liver tumors with iodine 124-labeled iodoazomycin galactopyranoside PET. (2008) (36)
- Air-generated electron contamination of 4 and 10 MV photon beams: a comparison of theory and experiment. (1985) (35)
- A framework for defining FLASH dose rate for pencil beam scanning (2020) (35)
- Auger electron contribution to bromodeoxyuridine cellular radiosensitization. (1989) (34)
- A new method of incorporating systematic uncertainties in intensity-modulated radiotherapy optimization. (2005) (33)
- Oxygen diffusion times in bacterial cells irradiated with high-intensity pulsed electrons: new upper limit to the lifetime of oxygen-sensitive species suspected to be induced at critical sites in bacterial cells. (1973) (32)
- Inactivation of DNA-PK by knockdown DNA-PKcs or NU7441 impairs non-homologous end-joining of radiation-induced double strand break repair (2018) (31)
- Oxygen radiosensitisation at low dose rate. (1985) (30)
- Over the next decade the success of radiation treatment planning will be judged by the immediate biological response of tumor cells rather than by surrogate measures such as dose maximization and uniformity. (2005) (30)
- Tumor hypoxia imaging in orthotopic liver tumors and peritoneal metastasis: a comparative study featuring dynamic 18F-MISO and 124I-IAZG PET in the same study cohort (2007) (29)
- Sensitization of low-dose-rate irradiation by nonlethal hyperthermia. (1991) (29)
- Computerized Video Time-Lapse (CVTL) Analysis of Cell Death Kinetics in Human Bladder Carcinoma Cells (EJ30) X-Irradiated in Different Phases of the Cell Cycle (2002) (29)
- Cellular and molecular repair of X-ray-induced damage: dependence on oxygen tension and nutritional status. (1985) (28)
- Irradiation of cells by single and double pulses of high intensity radiation: oxygen sensitization and diffusion kinetics. (1976) (28)
- Dose distribution of 125I sources in different tissues. (1990) (28)
- Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron. (1994) (28)
- Phase I dose escalation study using the deep inspiration breath hold technique to safely increase dose to 81 Gy in the treatment of inoperable non-small cell lung cancer (2000) (28)
- Moderate hyperthermia and low dose rate irradiation. (1988) (27)
- Using an onboard kilovoltage imager to measure setup deviation in intensity‐modulated radiation therapy for head‐and‐neck patients (2007) (27)
- Interaction of misonidazole and oxygen in the radiosensitization of mammalian cells. (1980) (27)
- When becometh less more? (1995) (27)
- A robotic system for 18F-FMISO PET-guided intratumoral pO2 measurements. (2009) (27)
- New wine in an old bottle? Dose escalation under dose-volume constraints: a model of conformal therapy of the prostate. (1996) (26)
- Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography (2010) (26)
- EUD but not QED. (2002) (25)
- Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies (2008) (25)
- Beam characteristics of a new generation 50 MeV racetrack microtron. (1995) (25)
- Evaluation of rapid dose map acquisition of a scanning liquid-filled ionization chamber electronic portal imaging device. (2003) (25)
- Results of a phase I dose escalation study in the treatment of inoperable non-small cell lung cancer (2003) (25)
- Repair of radiation induced damage--dependence on oxygen and energy status. (1988) (25)
- New radiotherapy technologies. (2003) (24)
- Comparison of Helzel and OxyLite Systems in the Measurements of Tumor Partial Oxygen Pressure (pO2) (2008) (24)
- Detection of S-phase overreplication following chronic hypoxia using a monoclonal anti-BrdUrd. (1985) (24)
- Modeling acute and chronic hypoxia using serial images of 18F-FMISO PET. (2009) (23)
- Experience in commissioning The Halcyon linac. (2019) (23)
- Measurement of dose distribution around Fletcher-Suit-Delcos colpostats using a Therados radiation field analyzer (RFA-3). (1984) (23)
- Preoperative irradiation, lymphadenectomy and 125iodine implant for patients with localized prostatic carcinoma: a correlation of implant dosimetry with clinical results. (1980) (22)
- Developments in nuclear magnetic resonance imaging and spectroscopy: application to radiation oncology. (2001) (21)
- Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks (2017) (21)
- Development of an image-guided robot for small animal research (2007) (21)
- In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression. (2009) (21)
- Stereotactic treatment of brain tumors with radioactive implants or external photon beams: radiobiophysical aspects. (1993) (20)
- The potential and limitations of the inverse radiotherapy technique (1995) (20)
- Perspectives of multidimensional conformal radiation treatment. (1993) (20)
- Measurements of Partial Oxygen Pressure (pO2) using the OxyLite System in R3327-AT Tumors under Isoflurane Anesthesia (2006) (19)
- 3-D conformal radiotherapy for carcinoma of the prostate. Clinical experience at the Memorial Sloan-Kettering Cancer Center. (1996) (19)
- Down-regulation of gadd153 by c-myc in rat fibroblasts and its effect on cell growth and radiation-induced apoptosis. (1996) (19)
- Modeling acute and chronic hypoxia using serial images of F18-FMISO PET. (2009) (19)
- Preclinical evaluation of the reliability of a 50 MeV racetrack microtron. (1994) (19)
- 3-D conformal radiation therapy for non-small cell lung carcinoma. Clinical experience at the Memorial Sloan-Kettering Cancer Center. (1996) (17)
- Expression of the bifunctional suicide gene CDUPRT increases radiosensitization and bystander effect of 5-FC in prostate cancer cells. (2009) (17)
- Dose-rate effect between 1 and 10 Gy/min in mammalian cell culture. (1984) (17)
- Treatment planning structure and process in the United States: a "Patterns of Care" study. (1995) (17)
- The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques1 (2001) (16)
- Respiration-phase-matched digital tomosynthesis imaging for moving target verification: a feasibility study. (2013) (16)
- Over the next decade the success of radiation treatment planning will be judged by the immediate biological response of tumor cells rather than by surrogate measures such as dose maximization and uniformity. (2005) (16)
- Contaminant electrons in the build-up region of a 4 MV photon beam. (1983) (16)
- Ten-year results of dose escalation with 3-dimensional conformal radiotherapy for patients with clinically localized prostate cancer (2003) (16)
- Hypoxia-targeted triple suicide gene therapy radiosensitizes human colorectal cancer cells (2014) (16)
- Technology assessment of multileaf collimation: a North American users survey. (1999) (16)
- 1008 Correlation of DVH and treatment planning variables with late rectal bleeding after 3D-CRT of prostate cancer: What is the best way to define the rectal length and volume? (1999) (15)
- Time scale of radiation-induced oxygen depletion and decay kinetics of oxygen-dependent damage in cells irradiated at ultrahigh dose rates. (1975) (15)
- A robotic system for F18-FMISO PET-guided intratumoral pO2 measurements. (2009) (15)
- Conformal radiation treatment: a critical appraisal. (1995) (14)
- Determining source strength and source distribution for a transperineal prostate implant (1996) (14)
- Glutathione depletion and cytotoxicity of buthionine sulphoximine and SR2508 in rodent and human cells. (1990) (14)
- Understanding radiation damage in late effect normal tissues: learning to negotiate the dose-volume-complication terrain or waiting for Godot? (1995) (14)
- Computer assisted treatment planning for 125I ophthalmic plaque radiotherapy. (1989) (14)
- Combined effects of misonidazole radiosensitization and hypoxic cell toxicity in mammalian cells. (1981) (14)
- 2211 Comparison of different respiratory levels in the treatment of lung cancer: Implications for gated treatment (1999) (13)
- Thermal response of oncogene-transfected rat cells. (1990) (13)
- Directional dependence of radiation fluence from 192Ir and 198Au sources. (1983) (13)
- Tumor control probability for permanent implants in prostate. (1993) (13)
- Pilot study of PET imaging of 124I-iodoazomycin galactopyranoside (IAZGP), a putative hypoxia imaging agent, in patients with colorectal cancer and head and neck cancer (2013) (13)
- Hyperthermia and gene therapy: Potential use of MicroPET imaging (2006) (12)
- Technologies of image guidance and the development of advanced linear accelerator systems for radiotherapy. (2011) (11)
- Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: the appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results. (2005) (11)
- Treatment planning for carcinoma of the cervix: a patterns of care study report. (1996) (11)
- High dose rate gynecological applications - radiobiological considerations based on the α-β model (1992) (11)
- Scylla and Charybdis: Longer Beam-on Time or Lesser Conformality—the Dilemma of Tomotherapy (2009) (11)
- Low-dose-rate irradiation of rat embryo cells containing the Ha-ras oncogene. (1993) (10)
- Changes in FDG Tumor Uptake during and after Fractionated Radiation Therapy in a Rodent Tumor Xenograft. (1999) (10)
- Respiratory gating of sliding window IMRT (2000) (10)
- Prolonged "ultra" low-dose-rate irradiation: effects on Chinese hamster cell population growth, survival, and radiation sensitivity. (1981) (10)
- Initial clinical evaluation of a respiratory gating radiotherapy system (2000) (9)
- Orbital tumor irradiation using non-coplanar beams. (1985) (9)
- Transfection of a human gene for the repair of X-ray- and EMS-induced DNA damage. (1986) (9)
- Radiosynthesis of [(131)I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker - is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker? (2009) (9)
- 112 The deep inspiration breath[ hold technique for the treatment of lung cancer: The first 200 treatments (1999) (9)
- Initial clinical experience with computer-controlled conformal radiotherapy using the MM50 microtron (1993) (9)
- Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells. (2003) (9)
- Final report of the 70.2 GY and 75.6 GY dose levels of a phase I dose escalation study using three dimensional conformal radiotherapy in the treatment of inoperable lung cancer (1998) (9)
- The effect of significant tumor reduction on the dose distribution in intensity modulated radiation therapy for head-and-neck cancer: a case study. (2009) (9)
- Image deconvolution in digital autoradiography: a preliminary study. (2008) (9)
- Presence of point mutations in the N-ras gene in radiation-transformed rat embryo cells. (1993) (8)
- Using measured dose distribution data of the Fletcher-Suit-Delclos colpostat in brachytherapy treatment planning. (1987) (8)
- Irradiation of Serratia marcescens by single and double pulses of high-intensity electrons: oxygen diffusion kinetics and lifetime of oxygen-sensitive species. (1975) (8)
- Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment (2015) (8)
- The effect of hypoxic cell sensitizers at different irradiation dose rates. (1987) (8)
- The number of beams in intensity-modulated treatments: In response to Drs. Söderström and Brahme (1996) (8)
- Rectal bleeding after conformal radiotherapy of prostate cancer and dose volume histograms (1998) (8)
- Design and Validation of an Image-Guided Robot for Small Animal Research (2006) (8)
- Beam characterization and monitoring of a high intensity pulsed electron source. (1973) (7)
- An equation for the dose response of radiation-induced apoptosis. (1995) (7)
- 78 The potential of optimized intensity modulation to escalate prostate dose to 86.4 GY (1996) (7)
- Computer automated diaphragm motion quantification in a fluoroscopic movie (2000) (7)
- Feasibility study of using low-energy intensity modulated radiation for the treatment of localized prostate carcinoma to high doses (2000) (7)
- Rat Embryo Cells Immortalized with Transfected Oncogenes Are Transformed by γ Irradiation (1992) (7)
- Interface dosimetry for I-125 sources. (1989) (6)
- Interaction of nitroimidazole sensitizers and oxygen in the radiosensitization of mammalian cells at ultrahigh dose rates. (1981) (6)
- Clinical implications of I-125 dosimetry of bone and bone-soft tissue interfaces. (1991) (6)
- Overlap detection and contour-tracking algorithms for critical organs--application to kidney. (1990) (6)
- Response to multiple radiation doses of human colorectal carcinoma cells infected with recombinant adenovirus containing dominant-negative Ku70 fragment. (2010) (6)
- Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model (2009) (6)
- Long-term outcome of high dose intensity modulated radiotherapy for clinically localized prostate cancer (2004) (5)
- Cone beam CT Acquisition of MV-scatter-free kilovoltage CBCT images during RapidArc TM or VMAT (5)
- Considering marker visibility during leaf sequencing for segmental intensity-modulated radiation therapy. (2009) (4)
- 46 Improved conformality and reduced toxicity with high-dose intensity modulated radiation therapy (IMRT) for patients with prostate cancer (1999) (4)
- Integrating respiratory gating into a megavoltage cone-beam CT (CBCT) system (2004) (4)
- Oxygen diffusion kinetics and reactive lifetimes in bacterial and mammalian cells irradiated with nanosecond pulses of high intensity electrons (1975) (4)
- The Lyman and a current parallel model: are they equivalent in predicting radiation induced lung toxicity (2000) (4)
- 29 Mixed modality intensity-modulated radiation therapy treatment planning for intracranial lesions (1997) (4)
- Molecular analysis of rat embryo cell transformants induced by α-particles (1993) (4)
- Activity uniformity of Ir-192 seeds. (1981) (4)
- Measurement of IMRT Head and Neck Setup Error Using an On-board Kilovoltage Imager (2005) (4)
- A triple suicide gene strategy that improves therapeutic effects and incorporates multi-modality molecular imaging for monitoring gene-functions (2013) (3)
- The treatment of large extraskeletal chondrosarcoma of the leg: comparison of IMRT and conformal radiotherapy techniques (2000) (3)
- Irradiation of bilateral orbital lymphoma: a non-coplanar technique with case reports. (1987) (3)
- NEUTRON--GAMMA COMPETITION FOLLOWING (d,d') REACTIONS. (1972) (3)
- Deep inspiration breath-hold technique and IMRT as methods to reduce volume of heart and liver in breast radiotherapy (2002) (3)
- Improved dose distribution with customized I-125 source loading in temporary interstitial implants. (1988) (3)
- Enhancement of SR 2508 (etanidazole) radiosensitization by buthionine sulphoximine at low-dose-rate irradiation. (1991) (3)
- Analysis of factors affecting the therapeutic gain in high dose rate gynecological implants relative to low dose rate implants. (1996) (3)
- 1043 Dose escalation for maxillary sinus cancer using intensity-modulated radiation therapy (IMRT) (1997) (3)
- WE-A-134-04: Comprehensive Evaluation of a Respiration-Phase-Matched Digital Tomosynthesis (DTS) Imaging Technique for Monitoring Moving Targets. (2013) (3)
- Response to multiple radiation doses of fibroblasts over-expressing dominant negative Ku70. (2008) (3)
- SU-DD-A3-05: Evaluation of Respiration-Correlated Digital Tomosynthesis for Soft Tissue Visualization (2006) (3)
- Delivery of intensity-modulated radiation therapy with a multileaf collimator: comparison of step-and-shoot and dynamic leaf motion methods (2000) (3)
- Abstract226: EUD and Dose-Volume Based Atlases of Complication Incidence: A Proposal for New Standards in Reporting Results of Treatment Protocols (2006) (2)
- The effect of DN (dominant-negative) Ku70 and reoxygenation on hypoxia cell-kill: Evidence of hypoxia-induced potentially lethal damage (2012) (2)
- Synergistic Effect of the \-myc Oncogene with H-ras on Radioresistance1 (2006) (2)
- WE‐D‐330A‐03: PO2 Measurements in Animal Tumors Using An Image‐Guided Robotic System (2006) (2)
- Iodine-125 implant and external beam irradiation in patients with localized pancreatic carcinoma. [Efficacy and complications] (1980) (2)
- Observation of interfractional variations in lung tumor position using respiratory gated and ungated megavoltage cone-beam CT (2008) (2)
- Neoplastic transformation dose response of oncogene-transfected rat embryo cells by gamma rays or 6 MeV alpha particles. (1994) (2)
- Evaluation of external-beam radiotherapy treatment plans incorporating treatment uncertainties: a new and essential method for dose-painting IMRT plans for prostate cancer (2002) (2)
- Hypoxia Imaging of Rodent Xenografts with 18F-Fluoromisonidazole: Comparison of Dynamic and Static PET Imaging (2012) (2)
- 2217 Volume effect on the radiation injury of rat kidney (1996) (2)
- Peritoneal Tumors Requires Physiologic Hypoxia (2010) (2)
- Analysis of geometric and dosimetric factors that correlate with late rectal bleeding after conformal radiotherapy of prostate cancer (1998) (2)
- Directional dependence of radiation fluence from /sup 192/Ir and /sup 198/Au sources (1983) (2)
- Dose parameters of /sup 125/I and /sup 192/Ir seed sources (1989) (2)
- MO-D-I-609-08: Validation of PET Hypoxia Tracers by Autoradiography and Fluorescent Microscopy (2005) (1)
- Computer-Controlled 3D Conformal Radiation Therapy (1995) (1)
- Quantifying the accuracy of affine transformations for modeling organ motion variabilities in external beam radiotherapy of prostate cancer (2000) (1)
- SU‐FF‐J‐49: Reducting of Motion Artifacts in Cone Beam CT Using a Patient Specific Respiratory Motion Model (2007) (1)
- The Effect of Proteasome Inhibitor Velcade on Tumor Microenvironment (2009) (1)
- Dosimetric consequence of three setup correction schemes for external-beam radiotherapy of prostate cancer (2002) (1)
- Coincidence sum peak assay of 125I activity using solid state detectors. (1980) (1)
- 32 Radiation-induced apoptosis: Cell cycle effects & dose fractionation (1995) (1)
- Dosimetry, field shaping and other considerations for intra-operative electron therapy using a clinac-35 (1979) (1)
- Preoperative radiation, lymphadenectomy and iodine-125 implant for selected patients with localized prostatic carcinoma: A correlation of implant dosimetry with clinical results (1979) (1)
- Using measured dose distribution data of the fletcher-Suit-Delclos colpostat in brachytherapy treatment planning (1988) (1)
- Optimization of conformal thoracic radiotherapy plans while using cone-beam CT imaging for treatment verification (2001) (1)
- Corrigendum to “Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia” [Neoplasia 11 (2009) 247-259] (2016) (1)
- RapidArc - Commissioning and QA Procedures (2008) (1)
- IMPROVED OUTCOME WITH HIGH DOSE 3-DIMENSIONAL CONFORMAL RADIOTHERAPY: RESULTS OF 1050 PATIENTS TREATED FOR LOCALIZED PROSTATE CANCER (1999) (1)
- CLINICAL UROLOGY: Letters to the EditorRE: HIGH DOSE RADIATION DELIVERED BY INTENSITY MODULATED CONFORMAL RADIOTHERAPY IMPROVES THE OUTCOME OF LOCALIZED CANCER (2001) (1)
- TU‐C‐332‐07: Accuracy and Reproducibility of Tumor Position During Prolonged and Multi‐Modality Animal Imaging Studies (2008) (1)
- Trifluoromisonidazole Detects Hypoxia-An In Vivo and In Vitro Multimodality Study (2010) (1)
- Design of an image-guided robot system for measurement, biopsy and injection in rodents (2004) (1)
- 10 – Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy (2010) (1)
- 124 Planning, delivery, and quality assurance of treatment with dynamic multileaf collimator for prostate: A strategy for large scale implementation (1996) (1)
- Noninvasive Multimodality Imaging of the Tumor Microenvironment : Registered Dynamic 1 H MRI and 18 F PET Studies of a Preclinical Model of Tumor Hypoxia (2008) (1)
- CT assisted assessment of bladder and rectum dose in gynecological implants (1988) (1)
- Plenary 5: Analyzing Serial Hypoxia Images From 18FMISO-PET: Modeling Transient and Chronic Hypoxia (2006) (1)
- Pitfalls in deducing radiobiological parameters for tumors from clinical data: a study of biopsy outcome after three-dimensional conformal radiation therapy (3D-CRT) of prostate cancer☆ (2000) (1)
- In Reply to Dahele et al. (2018) (1)
- Uptake of 18F-FDG in hypoxic micrometastases assessed by digital autoradiography (2008) (0)
- Response to ‘‘Comment on ‘Analysis of factors affecting the therapeutic gain in high dose rate gynecological implants relative to low dose rate implants’ ’’ [Med. Phys. 23, 419–425 (1996)] (1996) (0)
- 29 A new era in radiotherapy (1995) (0)
- Characterization of experimental lung metastases by contrast-enhanced microCT and F18-FDG microPET in nude mice (2007) (0)
- SU‐E‐I‐21: The Effects of MV Scatter on Image Quality of Cone Beam Scans Acquired Asynchronously during Rotational Delivery (2011) (0)
- Preliminary evaluation of cG250 and fragments for imaging hypoxia-regulated gene expression in solid tumors (2008) (0)
- [Activation of oncogenes by radon progeny x-ray]. Final technical report (1993) (0)
- Glucose metabolism in micrometastases by 18F-FDG autoradiography (DAR) (2009) (0)
- In response to Jones et al. (1996) (0)
- 325Conformal therapy of prostate cancer using intensity-modulated x-rays designed by the inverse technique and produced with dynamic multileaf collimation (1996) (0)
- The Treatment of Large Extraskeletal Comparison of IMRT and Conformal Radiotherapy Techniques (2000) (0)
- P04 25 SP – EFFECT OF RAS EXPRESSION ON THE COTRANSFORMING EFFICIENCY OF γ-IRRADIATION IN RAT EMBRYO CELLS (1991) (0)
- Studies on Mammalian Cells Exposed to Electrons at Ultrahigh Dose Rates from a 600 KV Field Emission Pulsed Source (1979) (0)
- of multidimensional conformal radiation treatment Perspectives (1993) (0)
- Smoothing intensity modulated beam profiles to facilitate delivery (2000) (0)
- Thermal Response of Oncogene-transfected Rat Cells1 (2006) (0)
- 2669 : Isoflurane Anesthesia Makes OxyLite More Useful in Oxygen Partial Tension Measurements (2006) (0)
- High dose rate gynecological applications--radiobiological considerations based on the alpha-beta model. (1992) (0)
- SU-FF-J-41: Monitoring of Intra-Fractional Patient Motion During High-Dose Extra-Cranial Paraspinal Radiosurgery (2005) (0)
- PO-0993: Evaluation of MV imaging dose for the first clinical Halcyon system (2018) (0)
- SU‐FF‐I‐95: The Use of Deformable Registration Model to Improve Visibility of the Lesion in Gated PET Images (2006) (0)
- 1048 Parotid gland sparing using inverse planning for radiotherapy of nasopharyngeal carcinomas (1997) (0)
- Treatment planning: Cervix - a patterns of care study report (1993) (0)
- Recent Advances in Cancer Imaging as Applied to Radiotherapy (2003) (0)
- Oxygen-dependent uptake of 2-nitroimidazole compounds - Comparison of in vitro uptake and tumor distribution (2007) (0)
- 128 Five year results for linac radiosurgery for arteriovenous malformations: Poor outcome for large AVMs (1997) (0)
- Isolation of hamster cell lines containing a human DNA repair gene (1985) (0)
- Triple Suicide Gene Therapy Radiosensitizes Prostate Cancer Cells (2008) (0)
- Abstract 2051: Hypoxia-induced triple suicide gene TK/CD/UPRT expression enhances cytotoxicity to GCV and 5-FC and radiosensitization in human colorectal cancer cells (2011) (0)
- P15 13 MP – PERMANENT IMPLANTS USING Au198, Pd103, & I125: RADIOBIOLOGICAL CONSIDERATIONS BASED ON THE LINEAR-QUADRATIC (α/β) MODEL (1991) (0)
- 2132 Analysis of biopsy outcome after three-dimensional radiation therapy of prostate cancer using dose distribution variables (1999) (0)
- Modeling the Development of Métastasesfrom Primary and Locally Recurrent l\imors: Comparison with a Clinical Data Base for Prostatic Cancer1 (2006) (0)
- 2771: Cone Beam CT Monitoring of IMRT Head and Neck Treatment (2006) (0)
- Preliminary clinical studies with the tumor hypoxia PET tracer 124I-IAZGP (2007) (0)
- RT3: Physics Acceptance and QA Procedures for IMRT (2001) (0)
- Using logical combinations of structures as a utility for inverse planning (1998) (0)
- Evaluation of tumor response to the antivascular agent DMXAA using 18F-FMISO PET (2009) (0)
- Comparison o f t he 5 -Year O utcome a nd M orbidity of T hree-Dimensiona l C onformal R adiotherapy Versus T ransperineal P ermanent I odine-125 I mplantation for E arly-Stage P rostatic C ancer (1999) (0)
- Intensity modulated radiation therapy (IMRT) verification using the frame averaging feature of Varian Mark II electronic portal imaging device (EPID) (2000) (0)
- SU‐FF‐J‐89: Intratumoral Pattern of FDG Uptake in Human Xenograft Models (2006) (0)
- Combination of Cytosine Deaminase With Uracil Phosphoribosyl Transferase With 5-fluorocytosine Radiosensitizes Rat Prostate Cancer Cells (2007) (0)
- Observation of Interfractional Variations in Lung Tumor Position Using Megavoltage Cone-Beam CT (2005) (0)
- Computer Assisted Treatment Planning for 125I Opthalmic Plaque Radiotherapy: International Journal of Radiation Oncology, Biology, Physics, Vol. 17, August 1989, pp. 405–410 (1990) (0)
- TU-C-332-09: Effects of Mild Temperature Hyperthermia On Rat HT29 Xenograft Hypoxia Measured with a Dual-Radiolabel Hypoxia Marker (2008) (0)
- MO‐D‐BRA‐01: Leibel Memorial Symposium: Advanced IMRT Planning and Delivery and Future Directions (2011) (0)
- Improved Dose Distribution With Customized I-125 Source Loading in Temporary Interstitial Implants (1989) (0)
- SU‐FF‐I‐109: Image Deconvolution in Autoradiography: A Preliminary Study (2007) (0)
- SU-E-J-64: Margins for Single-Fraction Treatments: Stereotactic Radiosurgery Brain Cases (2011) (0)
- TU‐D‐332‐08: Gd‐DTPA DCE‐MRI Assisted Image‐Guided PO2 Measurements in Rodent Tumor Xenografts (2008) (0)
- Proceedings of the 36th annual ASTRO meetingCarcinoma of the cervix patterns of care studies. Review of 1978,1983,1988-89 surveys (1994) (0)
- “Ultra” low dose-rate irradiation: Effects of prolonged exposures on population growth, survival and radiation sensitivity in cultured mammalian cells (1980) (0)
- 2630: A Preclinical Human Tumor Model for Non-Invasive Imaging of Hypoxia-Induced Gene Expression; Comparison of Endogenous and Exogenous Markers of Tumor Hypoxia (2006) (0)
- Abstract 1381: The effect of proteasome inhibitor velcade on tumor microenvironment (2010) (0)
- Activation of oncogenes by radon progeny and x-rays (1990) (0)
- Hypoxia-driven CDUPRT/5-FC Strategy Enhances the Radiosensitivity of Prostate Cancer Cells (2009) (0)
- TU‐D‐332‐01: Mapping of Viable Tumor Regions Using Gd‐DTPA DCE‐MRI (2008) (0)
- Imaging in three‐dimensional conformal radiation therapy (1995) (0)
- Non-invasive PET Imaging of Human Breast Xenografts: Influence of Tumor Hypoxia (2000) (0)
- Bortezomib Treatment Reduces Tumor Blood Flow and Perfusion as Measured by Dynamic Contrast-Enhanced 1 H MRI (2009) (0)
- A study of the effects of internal organ motion and setup error on dose escalation in conformal prostate treatments (1998) (0)
- 119 Use of radiobiological indices to guide dose escalation of the prostate cancer patients (1997) (0)
- Biophysical modelling: implications for conformation radiation treatment (1993) (0)
- EP-1738: Performance of a new EPID panel and opportunities for a fast MV-CBCT acquisition (2017) (0)
- Brachytherapy (1985) (0)
- 35: Development and Characterization of a Human Colorectal Tumor Cell Line Containing a Hypoxia-Inducible Dual-Modality Reporter Gene: Potential Use for Fluorescent and Nuclear Noninvasive Imaging of Tumor Hypoxia (2006) (0)
- Hypoxia in microscopic tumors detected by 131I-IAZGP digital autoradiography and immunofluorescent microscopy (2007) (0)
- Molecular analysis of rat embryo cell transformants induced by alpha-particles. (1993) (0)
- Chapter 6 – Three-Dimensional and Conformal Treatment Planning (2002) (0)
- In vivo Imaging of Tumor Hypoxia using 19 F MRS of Trifluoromisonidazole (2008) (0)
- In vivo 19 FMagnetic Resonance Spectroscopy and Chemical Shift Imaging of Tri-Fluoro-Nitroimidazole as a Potential Hypoxia Reporter in SolidTumors (2007) (0)
- Use of 18F-MISO PET Imaging to Monitor the Response of Colorectal Xenografts to DMXAA (2009) (0)
- 84 Heat shock improves viral vector distribution as evaluated by micropet imaging (2006) (0)
- A Dual-radiolabel Marker Quantifies Decrease in HT29 Xenograft Hypoxia Induced by Mild Temperature Hyperthermia (2012) (0)
- P04 26 SP – TRANSFORMATION OF RAT EMBRYO CELLS HARBORING A TRANSFECTED MYC ONCOGENE BY γ or α-RADIATION (1991) (0)
- Dedicating "Empowering Intensity Modulated Proton Therapy Through Physics and Technology: An Overview" to the Memory of Dr Michael Goitein. (2018) (0)
- 322Clinical implementation of dynamic multileaf-modulation for intensity-modulated treatments (1996) (0)
- P40 30 TP – RESPONSE OF MULTIDRUG RESISTANT CELLS TO HYPERTHERMIA (1991) (0)
- TH-E-330D-01: BIROW - Biomedical Imaging Research Opportunities Workshop: Intersociety Project to Accelerate Biomedical Imaging Discovery and Application - Part II (2006) (0)
- MO‐D‐BRC‐03: Concomitant RapidArc® and Acquisition of KV‐CBCT with Minimal MV Scatter (2011) (0)
- Rat embryo cells immortalized with transfected oncogenes are transformed by gamma irradiation. (1992) (0)
- High bone dose from i-125 may not contribute to necrosis — Physical considerations (1989) (0)
- COMMENT ON : LO ET AL. IJROBP 34(5) : 1113-1119 ; 1996. AUTHORS' REPLY (1996) (0)
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