Charles David Stout
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Chemistry Biology
Charles David Stout's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Chemistry Stanford University
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(Suggest an Edit or Addition)Charles David Stout's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution* (2004) (647)
- X-Ray Structures of the Hexameric Building Block of the HIV Capsid (2009) (475)
- ACONITASE AS IRON-SULFUR PROTEIN, ENZYME, AND IRON-REGULATORY PROTEIN (1996) (472)
- The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Å Resolution* (2004) (414)
- Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2*♦ (2007) (414)
- Heterocyclic Peptide Backbone Modifications in an α-Helical Coiled Coil (2004) (367)
- Structure of Human Microsomal Cytochrome P450 2C8 (2004) (361)
- An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution (2003) (339)
- Structure of Mammalian Cytochrome P450 2B4 Complexed with 4-(4-Chlorophenyl)imidazole at 1.9-Å Resolution (2004) (287)
- Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen (2005) (284)
- Refined crystal structure of Cd, Zn metallothionein at 2.0Åresolution (1991) (267)
- A heterocyclic peptide nanotube. (2003) (260)
- Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: Functional implications (1991) (249)
- Crystal structure of Cd,Zn metallothionein. (1985) (237)
- A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant. (2008) (213)
- Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain. (2000) (203)
- Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2. (1992) (202)
- Structure of activated aconitase: formation of the [4Fe-4S] cluster in the crystal. (1990) (197)
- Crystal structures of aconitase with isocitrate and nitroisocitrate bound. (1993) (187)
- Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes. (2003) (186)
- Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding. (2003) (171)
- Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution. (1991) (166)
- Crystal structure of an 82-nucleotide RNA–DNA complex formed by the 10-23 DNA enzyme (1999) (154)
- Structure of Microsomal Cytochrome P450 2B4 Complexed with the Antifungal Drug Bifonazole (2006) (154)
- Determinants of Cytochrome P450 2C8 Substrate Binding (2008) (151)
- Crystal structure of Aplysia ADP ribosyl cyclase, a homologue of the bifunctional ectozyme CD38 (1996) (149)
- The structure of aconitase (1989) (145)
- Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. (2010) (139)
- Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases. (2005) (134)
- Structural Characterization of the Complex between α-Naphthoflavone and Human Cytochrome P450 1B1* (2010) (127)
- Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins (2013) (126)
- Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain (2008) (120)
- Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1* (2010) (117)
- Atomically defined mechanism for proton transfer to a buried redox centre in a protein (2000) (117)
- Atomic coordinates and molecular conformation of yeast phenylalanyl tRNA. An independent investigation. (1976) (108)
- High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment (2011) (108)
- The reaction of fluorocitrate with aconitase and the crystal structure of the enzyme-inhibitor complex. (1996) (108)
- Refinement of the 7 Fe ferredoxin from Azotobacter vinelandii at 1.9 A resolution. (1989) (101)
- Crystallographic studies of Xe and Kr binding within the large internal cavity of cytochrome ba3 from Thermus thermophilus: structural analysis and role of oxygen transport channels in the heme-Cu oxidases. (2008) (96)
- Structure of the Human Lung Cytochrome P450 2A13* (2007) (95)
- Structural Diversity of Eukaryotic Membrane Cytochrome P450s* (2013) (95)
- Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution (2010) (91)
- Conformational flexibility in the flap domains of ligand-free HIV protease. (2007) (91)
- The mechanism of aconitase: 1.8 Å resolution crystal structure of the S642A:citrate complex (1999) (83)
- Species-specific sequences of abalone lysin, the sperm protein that creates a hole in the egg envelope. (1990) (82)
- Structural Characterization of Human Cytochrome P450 2C19 (2012) (82)
- Automated docking in crystallography: Analysis of the substrates of aconitase (1993) (82)
- Crystal structures of aconitase with trans-aconitate and nitrocitrate bound. (1993) (82)
- High-resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: analysis and comparison. (2003) (82)
- Crystal and molecular structure of yeast phenylalanyl transfer RNA. Structure determination, difference Fourier refinement, molecular conformation, metal and solvent binding (1978) (81)
- Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound* (2012) (80)
- Abalone lysin: the dissolving and evolving sperm protein (2000) (78)
- Iron-sulfur clusters and protein structure of Azotobacter ferredoxin at 2.0 A resolution. (1982) (75)
- A Conserved Mechanism for Sulfonucleotide Reduction (2005) (74)
- Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding* (2015) (73)
- Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules. (2012) (72)
- Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution. (2006) (67)
- A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus. (2005) (67)
- CD38 signaling in B lymphocytes is controlled by its ectodomain but occurs independently of enzymatically generated ADP-ribose or cyclic ADP-ribose. (1999) (65)
- Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus (1996) (65)
- Iron-sulfur clusters in Azotobacter ferredoxin at 2.5 A resolution. (1980) (64)
- Structural Basis of Drug Binding to CYP46A1, an Enzyme That Controls Cholesterol Turnover in the Brain* (2010) (62)
- Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1 (2013) (61)
- Crystal structure of transhydrogenase domain III at 1.2 Å resolution (2000) (60)
- Site-directed mutagenesis of Azotobacter vinelandii ferredoxin I: [Fe-S] cluster-driven protein rearrangement (1989) (60)
- Structure of a 7Fe ferredoxin from Azotobacter vinelandii. (1981) (60)
- Azotobacter vinelandii ferredoxin I. Aspartate 15 facilitates proton transfer to the reduced [3Fe-4S] cluster. (1993) (58)
- Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. (2006) (57)
- Crystal structure of Azotobacter cytochrome c5 at 2.5 A resolution. (1985) (57)
- 7-Iron ferredoxin revisited. (1988) (56)
- The crystal structure of lysin, a fertilization protein. (1993) (55)
- Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel. (2011) (54)
- Heterocyclic peptide backbone modifications in an alpha-helical coiled coil. (2004) (52)
- Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography* (2010) (52)
- Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. (2007) (50)
- Structure of Azotobacter vinelandii 7Fe ferredoxin. Amino acid sequence and electron density maps of residues. (1983) (49)
- 3'-Phosphoadenosine-5'-phosphosulfate reductase in complex with thioredoxin: a structural snapshot in the catalytic cycle. (2007) (48)
- Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. (2004) (48)
- The crystal structure of NADPH: Ferredoxin reductase from azotobacter vinelandii (1998) (48)
- Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains (2011) (47)
- Combined microspectrophotometric and crystallographic examination of chemically reduced and X-ray radiation-reduced forms of cytochrome ba3 oxidase from Thermus thermophilus: structure of the reduced form of the enzyme. (2009) (47)
- Structure of Azotobacter vinelandii 7Fe ferredoxin at 1.35 A resolution and determination of the [Fe-S] bonds with 0.01 A accuracy. (1998) (44)
- Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4. (2007) (43)
- Steric and conformational features of the aconitase mechanism (1995) (43)
- Alternative conformations of a nucleic acid four-way junction. (2000) (42)
- Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . (2010) (42)
- Crystal structures of ferredoxin variants exhibiting large changes in [Fe–S] reduction potential (2002) (42)
- Azotobacter vinelandii ferredoxin I. Alteration of individual surface charges and the [4FE-4S]2+/+ cluster reduction potential. (1994) (41)
- Crystal structures of oxidized and reduced Azotobacter vinelandii ferredoxin at pH 8 and 6. (1993) (41)
- Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. (2009) (39)
- Oxidized and reduced Azotobacter vinelandii ferredoxin I at 1.4 A resolution: conformational change of surface residues without significant change in the [3Fe-4S]+/0 cluster. (1999) (38)
- Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. (2000) (37)
- Circular dichroism and magnetic circular dichroism of Azotobacter vinelandii ferredoxin I. (1991) (37)
- Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity. (2011) (36)
- Mechanisms of chain folding in nucleic acids. The (ω′,ω) plot and its correlation to the nucleotide geometry in yeast tRNAPhe1 (1976) (36)
- Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3 (2007) (36)
- Crystallographic Fragment‐Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease (2014) (36)
- Inherent protein structural flexibility at the RNA-binding interface of L30e. (2003) (36)
- Binding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1 (2013) (35)
- Structure of mammalian cytochrome P450 2B4 (2000) (35)
- Investigation by site‐directed mutagenesis of the role of cytochrome P450 2B4 non‐active‐site residues in protein–ligand interactions based on crystal structures of the ligand‐bound enzyme (2012) (35)
- Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6. (2013) (34)
- Magnetic resonance and mass spectrum of .pi.-cyclopentadienyl-.pi.-cycloheptatrienylvanadium. Mass spectral rearrangement to bis(benzene)vanadium (1970) (34)
- Aconitase as Ironminus signSulfur Protein, Enzyme, and Iron-Regulatory Protein. (1996) (34)
- The amino acid sequence of the dihaem cytochrome c4 from the bacterium Azotobacter vinelandii. (1984) (34)
- Structure-based engineering of internal cavities in coiled-coil peptides. (2005) (34)
- Halogen‐π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human P450 2B6 Substrate Selectivity. (2017) (34)
- Division of labor in transhydrogenase by alternating proton translocation and hydride transfer (2015) (34)
- Small molecule regulation of protein conformation by binding in the Flap of HIV protease. (2013) (33)
- Crystal structure and subunit dynamics of the abalone sperm lysin dimer: egg envelopes dissociate dimers, the monomer is the active species (1995) (33)
- In Silico and Intuitive Predictions of CYP46A1 Inhibition by Marketed Drugs with Subsequent Enzyme Crystallization in Complex with Fluvoxamine (2012) (32)
- Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. (2012) (32)
- Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: implications for allosteric modulation of cytochrome P450 catalysis. (2013) (32)
- X-ray structure of metallothionein. (1991) (32)
- Alteration of the Reduction Potential of the [4Fe-4S]2+/+ Cluster of Azotobacter vinelandii Ferredoxin I* (1999) (32)
- Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening. (2002) (31)
- Purification and crystallization of N-terminally truncated forms of microsomal cytochrome P450 2C5. (2002) (31)
- Redox protein electron-transfer mechanisms: electrostatic interactions as a determinant of reaction site in c-type cytochromes. (1989) (30)
- Crystal structures of transhydrogenase domain I with and without bound NADH. (2002) (29)
- X-ray absorption studies of the copper-beta domain of rat liver metallothionein. (1986) (29)
- Site-directed mutagenesis of Azotobacter vinelandii ferredoxin I: cysteine ligation of the [4Fe-4S] cluster with protein rearrangement is preferred over serine ligation. (1995) (27)
- Aconitase: An Iron—Sulfur Enzyme (1992) (27)
- Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains. (2005) (27)
- Single crystals of cadmium, zinc metallothionein. (1985) (26)
- Spectroscopic studies of ferricyanide oxidation of Azotobacter vinelandii ferredoxin I. (1984) (25)
- Complex Formation between Azotobacter vinelandiiFerredoxin I and Its Physiological Electron Donor NADPH-Ferredoxin Reductase* (1999) (25)
- Electron-transfer reactions between flavodoxin semiquinone and c-type cytochromes: comparisons between various flavodoxins. (1986) (25)
- Reconstitution of Azotobacter vinelandii ferredoxin I as a {2[4Fe‐4S]1+/2+} protein (1984) (25)
- [4Fe-4S]-cluster-depleted Azotobacter vinelandii ferredoxin I: a new 3Fe iron-sulfur protein. (1985) (24)
- Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I. (2003) (24)
- The species-specificity and structure of abalone sperm lysin (1994) (24)
- The crystal structure of a fusagenic sperm protein reveals extreme surface properties. (2001) (24)
- Structure of C42D Azotobacter vinelandii FdI (2000) (23)
- The high resolution crystal structure of green abalone sperm lysin: implications for species-specific binding of the egg receptor. (2000) (22)
- Crystallization of ADP‐ribosyl cyclase from Aplysia californica (1996) (22)
- Structural insights into the mechanisms of drug resistance in HIV-1 protease NL4-3. (2006) (22)
- Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1 (2008) (22)
- The Proton Channel of the Energy-transducing Nicotinamide Nucleotide Transhydrogenase of Escherichia coli * (2002) (21)
- Crystallization of the 10-23 DNA enzyme using a combinatorial screen of paired oligonucleotides. (1999) (21)
- AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery. (2013) (20)
- Iron-sulfur cluster in aconitase. Crystallographic evidence for a three-iron center. (1985) (20)
- 1.35 and 2.07 A resolution structures of the red abalone sperm lysin monomer and dimer reveal features involved in receptor binding. (2000) (19)
- Cytochrome p450 conformational diversity. (2004) (19)
- Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: a combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B). (2012) (18)
- Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. (2004) (18)
- Magnetic studies and the crystal and molecular structure of [enH2][V(hedta-H)]2.cntdot.2H2O: a novel di-.mu.-alcoxy-bridged dimer of seven-coordinate vanadium(III) (1981) (18)
- Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism (2016) (17)
- Selective oxidative destruction of iron‐sulfur clusters (1985) (17)
- The circumsphere as a tool to assess distortion in [4Fe-4S] atom clusters (2003) (17)
- A T14C Variant of Azotobacter vinelandii Ferredoxin I Undergoes Facile [3Fe-4S]0 to [4Fe-4S]2+Conversion in Vitro but Not in Vivo * (1998) (17)
- Conformational change in the NADP(H) binding domain of transhydrogenase defines four states. (2003) (17)
- Azotobacter vinelandii Ferredoxin I (2002) (16)
- Structure of the iron–sulphur clusters in Azotobacter ferredoxin at 4.0 Å resolution (1979) (16)
- A Structural Snapshot of CYP2B4 in Complex with Paroxetine Provides Insights into Ligand Binding and Clusters of Conformational States (2013) (15)
- Review and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channel (2015) (15)
- Crystallographic analysis of two site-directed mutants of Azotobacter vinelandii ferredoxin. (1990) (14)
- Ligand access to the active site in Thermus thermophilus ba(3) and bovine heart aa(3) cytochrome oxidases. (2013) (14)
- Essential Glycine in the Proton Channel of Escherichia coli Transhydrogenase* (2003) (14)
- Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison (2015) (13)
- Crystal Structure of Human Microsomal P450 3A4 (2004) (13)
- Crystal Structure of CYP 24 A 1 , a Mitochondrial Cytochrome P 450 Involved in Vitamin D Metabolism (2010) (12)
- Acrosomal Proteins of Abalone Spermatozoa (1999) (11)
- Critical Role of Water Molecules in Proton Translocation by the Membrane-Bound Transhydrogenase. (2017) (11)
- Site-directed mutagenesis of Azotobacter vinelandii ferredoxin I: [Fe-S] cluster-driven protein rearrangement. (1989) (11)
- Y13C Azotobacter vinelandii Ferredoxin I (1997) (10)
- Stereochemistry of nucleic acids and their constituents. XXI. The crystal and molecular structure of bis-(4-aminoimidazole-5-carboxamidoxime)copper(II) perchlorate, a degradation product of adenine N1-oxide (1972) (10)
- Human CYP 2 D 6 Structure 1 CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P 450 2 D 6 WITH PRINOMASTAT BOUND (2012) (10)
- X‐ray Crystal Structure of the Cytochrome P450 2B4 Active Site Mutant F297A in Complex with Clopidogrel: Insights into Compensatory Rearrangements of the Binding Pocket (2013) (10)
- Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. (2011) (9)
- Structure of mammalian cytochrome P450 2B4 with bound 4-(4-chlorophenyl)imidazole (2004) (9)
- Aconitase as Iron‐Sulfur Protein, Enzyme, and Iron‐Regulatory Protein (1997) (9)
- The novel purification and biochemical characterization of a reversible CYP24A1:adrenodoxin complex (2013) (9)
- Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. (2016) (9)
- Acid pH crystallization of the basic protein lysin from the spermatozoa of red abalone (Haliotis rufescens). (1994) (9)
- Conserved Glycine 232 in the Ligand Channel of ba3 Cytochrome Oxidase from Thermus thermophilus (2014) (8)
- Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations. (2016) (8)
- Combinatorial crystallization of an RNA-protein complex. (2003) (8)
- Towards novel therapeutics for HIV through fragment-based screening and drug design. (2014) (8)
- An unexpected outcome of surface engineering an integral membrane protein: improved crystallization of cytochrome ba(3) from Thermus thermophilus. (2007) (7)
- FERREDOXIN REDUCTASE FROM AZOTOBACTER VINELANDII (1998) (7)
- Structure of Human Microsomal Cytochrome P450 (CYP) 2C19 (2012) (7)
- Bicalutamide-CYP 46 A 1 interactions 1 Binding of a Cyano-and Fluoro-Containing Drug Bicalutamide to Cytochrome P 450 46 A 1 : Unusual Features and Spectral Response * (2013) (7)
- Two crystal forms of Azotobacter ferredoxin. (1979) (7)
- The crystal structure of aconitase (1989) (6)
- Ferredoxins Containing Two Different Fe/S Centers of the Forms [4Fe–4S] and [3Fe–4S] (2006) (6)
- Diffraction quality crystals of lysin from spermatozoa of the red abalone (Haliotis rufescens). (1990) (6)
- Role of the Conserved Valine 236 in Access of Ligands to the Active Site of Thermus thermophilus ba3 Cytochrome Oxidase. (2017) (6)
- Crystallization and preliminary X-ray diffraction studies of a toxic crystal protein from a subspecies of Bacillus thuringiensis. (1988) (5)
- Single crystals of the iron-sulfur enzyme aconitase. (1982) (5)
- Preliminary crystallographic data for Azotobacter cytochrome c5. (1978) (5)
- Induced fit, drug design, and dUTPase. (2004) (4)
- STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA (2000) (4)
- X-ray absorption spectroscopy of 3-Fe clusters in FeS proteins (1983) (4)
- Diffraction quality crystals of protein X from Azotobacter vinelandii. (1994) (4)
- Expression, purification, crystallization and preliminary X-ray analysis of the olfactomedin domain from the sea urchin cell-adhesion protein amassin. (2006) (4)
- 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment (2011) (3)
- Crystal structures of ferricyanide-oxidized [Fe-S] clusters in (1998) (3)
- erratum: Atomically defined mechanism for proton transfer to a buried redox centre in a protein (2000) (3)
- Crystal structure of bis-(4-aminoimidazole-5-carboxamide oxime)copper(II) perchlorate. A degradation product of adenine N1-oxide (1971) (3)
- Crystal structures of ferricyanide-oxidized [Fe-S] clusters in Azotobacter vinelandii ferredoxin I (1998) (3)
- Mechanisms of chain folding in nucleic acids. The (omega, omega) plot and its correlation to the nucleotide geometry in yeast tRNAPhe1. (1976) (2)
- A Conserved Mechanism for Sulfonucleotide (2005) (1)
- Crystals of cadmium, zinc metallothionein. (1984) (1)
- Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone (2007) (1)
- Structure of Recombinant Cytochrome ba3 Oxidase from Thermus thermophilus (2005) (1)
- Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles (2004) (1)
- ADP-Ribose or Cyclic ADP-Ribose Independently of Enzymatically Generated Controlled by Its Ectodomain but Occurs CD 38 Signaling in B Lymphocytes Is (1999) (1)
- CRYSTAL STRUCTURE OF ACONITASE WITH ISOCITRATE (1998) (1)
- Competitive replacement of thioridazine by prinomastat in crystals of cytochrome P450 2D6 (2012) (1)
- Crystal structure of Cd,Zn metallothionein. (1987) (1)
- Human Cytochrome P450 (CYP) 2D6 - Prinomastat Complex (2012) (1)
- Crystallographic studies of aconitase (1994) (1)
- Crystal structure of FIV dUTP pyrophosphatase (1996) (1)
- Crystal structure of Cd,Zn metallothionein at 1.9 Å resolution (1987) (1)
- CRYSTAL STRUCTURE OF AZOTOBACTER CYTOCHROME C5 AT 2.5 ANGSTROMS RESOLUTION (1984) (1)
- The Crystal Structure of Human, Nicotine Metabolizing Cytochrome P450 2A6 (2005) (1)
- DIFFERENCE FOURIER REFINEMENT OF THE STRUCTURE OF MONOCLINIC YEAST tRNAPhe AT 2.5 Å RESOLUTION (1981) (1)
- Dispensable iron-sulfur clusters: the interconversion of aconitase with the RNA-binding protein, IRE-BP (1994) (1)
- FERRICYANIDE OXIDIZED FDI (1998) (0)
- An Anti-Parallel Four Helix Bundle Mutant pLI-E20C (2004) (0)
- Structure of CYP2B6 (Y226H/K262R) with additional mutation Y244W in complex with alpha-Pinene (2016) (0)
- Crystal Structure of 6s-98S FIV Protease with Darunavir bound (2011) (0)
- TL-3 inhibited Trp6Ala HIV Protease with 1-bromo-2-napthoic acid bound in exosite (2013) (0)
- Crystallographic Studies of Azotobacter Ferredoxin A Seven-Iron Protein (1982) (0)
- Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide) (2004) (0)
- CYP2C8dH complexed with montelukast (2007) (0)
- 7-FE FERREDOXIN FROM AZOTOBACTER VINELANDII AT PH 8.5, 100 K, 1.35 A (1998) (0)
- Crystal Structure of P4502C9 with Flurbiprofen bound (2004) (0)
- HIV-1 Protease NL4-3 3X mutant in complex with inhibitor, TL-3 (2006) (0)
- Crystal Structure of the P50A mutant of ferredoxin I at 1.65 A Resolution (2003) (0)
- APLYSIA ADP RIBOSYL CYCLASE (1997) (0)
- Structural Characterization of 3Fe Clusters in Fe-S Proteins by EXAFS (1984) (0)
- CRYSTAL STRUCTURE OF ACONITASE WITH TRANSACONITATE BOUND (1993) (0)
- HIV-1 Protease NL4-3 in complex with inhibitor, TL-3 (2006) (0)
- DEVELOPMENT OF AN INDEX OF REFRACTION SENSOR FOR ATMOSPHERIC SOUNDING. (1962) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus (2013) (0)
- Crystal Structure of P450 2B6 (Y226H/K262R) in complex with two molecules of Amlodipine (2012) (0)
- Apo HIV Protease (PR) dimer in closed form with fragment 1F1-N in the outside/top of flap (2013) (0)
- Performance Characteristics of a High-Temperature Servomechanism for Reactor Control Rods (1962) (0)
- Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole (2007) (0)
- Conformational plasticity of cytochrome P450 2B4: crystallographic and solution studies (2006) (0)
- Crystal structure of R. rubrum transhydrogenase domain III bound to NADPH (2003) (0)
- Structure of Cytochrome P450 2B4 with Bound Bifonazole (2005) (0)
- Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti-platelet Drug Clopidogrel (2013) (0)
- THE CRYSTAL STRUCTURE OF A FERTILIZATION PROTEIN (1993) (0)
- Crystal Structure Of Human Microsomal P450 2A6 with the inhibitor (5-(Pyridin-3-yl)furan-2-yl)methanamine bound (2006) (0)
- The Roles of the Highly Conserved Amino Acid Residues Val236 and Gly232 in the Ligand Channel of Ba3 Cytochrome C Oxidase from Thermus Thermophilus (2014) (0)
- E. Molecular Design of Metalloproteins (2009) (0)
- Aconitase mechanism from crystal structures of the enzyme complexed to substrates and inhibitors. (1993) (0)
- 7-FE FERREDOXIN FROM AZOTOBACTER VINELANDII, NA DITHIONITE REDUCED, PH 8.5, 1.4A RESOLUTION, 100 K (1998) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus (2013) (0)
- Voriconazole complex of Cytochrome P450 46A1 (2010) (0)
- HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER (2000) (0)
- CYP24A1 and the Metabolism of Vitamin D (2010) (0)
- Human Cytochrome P450 2D6 Ajmalicine Complex (2015) (0)
- COMPLEX WITH 4-HYDROXY-TRANS-ACONITATE (1996) (0)
- Crystal Structure of R. rubrum Transhydrogenase Domain I without Bound NAD(H) (2002) (0)
- Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol (2010) (0)
- An anti-parallel to parallel switch. (2004) (0)
- HIV protease (PR) dimer with acetate in exo site and peptide in active site (2012) (0)
- Microsomal P450 2A6 with the inhibitor Adrithiol bound (2006) (0)
- Structure of HIV Protease NL4-3 in an Unliganded State (2007) (0)
- HIV Protease (PR) dimer without inhibitor; acetate in exo site (2010) (0)
- Structure of Human Lung Cytochrome P450 2A13 with indole bound in two alternate conformations (2007) (0)
- Crystal structure of Azotobacter cytochrome c5 at 2.5 Ã (1984) (0)
- Structure of HIV protease 6X mutant in apo form (2007) (0)
- CRYSTAL STRUCTURE OF P47S MUTANT OF FERREDOXIN I (2000) (0)
- The structure of FIV 12S protease in complex with TL-3 (2007) (0)
- Atomiccoordinates andmolecular conformation ofyeastphenylalanyl tRNA. Anindependent investigation. (1976) (0)
- COMPLEX OF ACONITASE R644Q MUTANT WITH FLUOROCITRATE (1997) (0)
- COMPLEX OF ACONITASE S642A MUTANT WITH FLUOROCITRATE (1997) (0)
- Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate (2008) (0)
- Human cytochrome P450 2D6 with two thioridazines bound in active site (2012) (0)
- 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment (2011) (0)
- Crystal Structure of P450 2B4(H226Y) in complex with Amlodipine (2012) (0)
- COMPLEX OF ACONITASE S642A MUTANT WITH ISOCITRATE (1997) (0)
- Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5 (2009) (0)
- CRYSTAL STRUCTURE AND SUBUNIT DYNAMICS OF THE LYSIN DIMER: EGG ENVELOPES DISSOCIATE DIMERS, THE MONOMER IS THE ACTIVE SPECIES (1995) (0)
- Crystal Structure of Human Microsomal P450 2A6 N297Q (2007) (0)
- HIV Protease (PR) dimer with inhibitor TL-3 bound and fragment 2F4 in the outside/top of flap (2010) (0)
- pLI E20C is antiparallel (2006) (0)
- Refined structure of azotobacter ferredoxin (iron-sulfur protein III) at 2.0 Ã resolution (1981) (0)
- A high‐resolution crystal structure of ligand‐free cytochrome P450 2B4 (H226Y) in a closed conformation (2010) (0)
- Crystal structure of human cytochrome P450 46A1 (2008) (0)
- Strucutre of the oxidized Hipip from thermochromatium tepidum at 1.4 angstrom resolution (2006) (0)
- Crystal Structure of a Cytochrome P450 2b6 Genetic Variant in Complex With the Inhibitor 4-(4-Chlorophenyl)Imidazole at 2.0-Angstrom Resolution (2012) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus (2012) (0)
- Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex (2005) (0)
- CRYSTAL STRUCTURE OF GREEN ABALONE SP18 (2000) (0)
- An anti-parallel four helix bundle (acetimide modification). (2004) (0)
- Crystal Structure of Human Microsomal P450 2A6 with Coumarin Bound (2005) (0)
- Crystal structure of Thermus thermophilis transhydrogeanse domain II dimer SeMet derivative (2014) (0)
- Crystal Structure of Human CYP46A1 P450 with bicalutamide Bound (2013) (0)
- Crystal Structure Of Cytochrome P450 2B35 from Desert Woodrat Neotoma Lepida in complex with 4-(4-chlorophenyl)imidazole (2016) (0)
- HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite (2018) (0)
- Structure of HIV protease 6X mutant in complex with AB-2. (2007) (0)
- HIGH RESOLUTION STRUCTURE OF RED ABALONE LYSIN DIMER (2000) (0)
- The Structure of Human Cytochrome P450 2C19: Active site differences between P450s 2C19 and 2C9 (2008) (0)
- Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit in P2(1) (2014) (0)
- Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene (2013) (0)
- DEVELOPMENT OF AM OZONE SENSOR FOR ATMOSPHERIC SOUNDING. (1961) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus (2013) (0)
- I40N MUTANT OF AZOTOBACTER VINELANDII FDI (1997) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus (2013) (0)
- STRUCTURE AND PROPERTIES OF C20S FDI MUTANT (1994) (0)
- TL-3 inhibited Trp6Ala HIV Protease (2013) (0)
- An anti-parallel four helix bundle. (2004) (0)
- Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8 (2004) (0)
- Heterocyclic Peptide Backbone Modification in GCN4-pLI Based Coiled Coils: Replacement of E(22)L(23) (2004) (0)
- Transhydrogenase coupling proton translocation and hydride transfer (2014) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus (2012) (0)
- Crystal Structure of the Alpha1 dimer of Thermus thermophilus Transhydrogenase in P4(3) (2014) (0)
- Crystals ofCadmium, ZincMetalothionein (1984) (0)
- pLI mutant E20C L16G Y17H, antiparallel (2005) (0)
- Crystal Structure of Cytochrome P450 2B37 from Desert Woodrat in complex with 4-(4-chlorophenyl)imidazole (2016) (0)
- Crystal structure of Thermus thermophilis transhydrogeanse domain II dimer (2014) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus (2012) (0)
- Dual Ligand Complexes of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 with Amlodipine Reveal Substrate Access Channels into the Active Site (2012) (0)
- D15K/K84D MUTANT OF AZOTOBACTER VINELANDII FDI (1998) (0)
- ACONITASE R644Q:FLUOROCITRATE COMPLEX (1998) (0)
- Non-natural backbone modifications in peptide based supramolecular designs (2005) (0)
- Two Conformations of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism‐Based Inactivator tert‐Butylphenylacetylene (2011) (0)
- Crystal Structure of Human Microsomal P450 2A6 N297Q/I300V (2007) (0)
- CYP2C8dH complexed with 2 molecules of 9-cis retinoic acid (2007) (0)
- Crystal Structure of the Rieske protein from Thermus thermophilus (2003) (0)
- Progress report on the structure determination of Cd, Zn metallothionein (1984) (0)
- S642A:FLUOROCITRATE COMPLEX OF ACONITASE (1999) (0)
- Characterization of the malformed, recombinant cytochrome rC552 (2004) (0)
- Crystal structure of cytochrome 2B4 in complex with the anti-platelet drug clopidogrel (2010) (0)
- CRYSTAL STRUCTURE OF THE C42D MUTANT OF AZOTOBACTER VINELANDII 7FE FERREDOXIN (FDI) (2000) (0)
- REFINEMENT OF THE 7 FE FERREDOXIN FROM AZOTOBACTER AT 1.9 ANGSTROMS RESOLUTION (1988) (0)
- Antiparallel Configuration of pLI E20S (2006) (0)
- HIV Protease (PR) with inhibitor TL-3 and fragment hit 4D9 by soaking (2010) (0)
- Crystal Structure of Human Microsomal P450 2A6 L240C/N297Q (2007) (0)
- Structure-Function Analysis of Mammalian CYP 2 B Enzymes Using 7-Substituted Coumarin Derivatives as Probes : Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism s (2016) (0)
- Structure of CYP2B4 F244W in a ligand free conformation (2016) (0)
- Tranylcypromine complex of Cytochrome P450 46A1 (2010) (0)
- CRYSTAL STRUCTURE OF F25H FERREDOXIN 1 MUTANT FROM AZOTOBACTER VINELANDII AT 1.75 ANGSTROM RESOLUTION (2000) (0)
- Microsomal P450 2A6 with the inhibitor N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound (2006) (0)
- Thioperamide complex of Cytochrome P450 46A1 (2010) (0)
- Automated grid-based XFEL diffraction studies of single macromolecular crystals (2014) (0)
- Apo Wild-type HIV Protease in the open conformation (2007) (0)
- Clotrimazole complex of Cytochrome P450 46A1 (2010) (0)
- Single ligand occupancy crystal structure of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole (2009) (0)
- Azotobacter vinelandii ferredoxin I: Aspartate-15 facilitates proton transfer to the [3Fe4S]0 cluster (1993) (0)
- Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-4 DMPC Bicelle (2013) (0)
- Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min (2008) (0)
- Iron–sulfur cluster in aconitase at 3.0 Å resolution (1987) (0)
- Crystal structure of cytochrome P450-cam with a fluorescent probe D-4-AD (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-butyl-amide) (2004) (0)
- Structure of a 7 Fe Ferredoxin from Azotobacter uineZandii * (2001) (0)
- Iron-Sulfur Cluster in Aconitase (2001) (0)
- HIV Protease (PR) dimer with inhibitor TL-3 bound and fragment 1F1 in the outside/top of flap (2010) (0)
- Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS (2006) (0)
- HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment AK-2097 in the outside/top of flap (2013) (0)
- MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH DICLOFENAC (2003) (0)
- HIV Protease with fragment 4D9 bound (2010) (0)
- CYP2C8DH COMPLEXED WITH TROGLITAZONE (2008) (0)
- CRYSTAL STRUCTURE OF THE L44S MUTANT OF FERREDOXIN I (2000) (0)
- Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization (2012) (0)
- Human Cytochrome P450 2A13: Correlation between a 2.35 Å Structure and Ligand Binding (2006) (0)
- HIV Protease (PR) with inhibitor TL-3 bound, and DMSOs in exo site (2010) (0)
- CRYSTAL STRUCTURE OF A NUCLEIC ACID FOUR-WAY JUNCTION (2000) (0)
- Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. (2011) (0)
- A Structural Snapshot of Cytochrome P 450 2 B 4 in Complex with Paroxetine Provides Insights into Ligand Binding and Clusters of Conformational States (2013) (0)
- TL-3 inhibited Trp6Ala HIV Protease with 3-bromo-2,6-dimethoxybenzoic acid bound in flap site (2013) (0)
- Protein Tuning of Ligand Pathways and Metal Centers in Heme-Copper Oxidases (2013) (0)
- The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus (2012) (0)
- Crystal Structure of Cytochrome P450 2B6 (Y226H/K262R) in complex with alpha-Pinene. (2013) (0)
- Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound (2012) (0)
- FIV DUTP PYROPHOSPHATASE (1997) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus (2013) (0)
- Crystal structure of ADP-ribosyl cyclase (1996) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus (2013) (0)
- CYP2C8dH complexed with felodipine (2007) (0)
- HIV-1 Protease NL4-3 1X mutant (2006) (0)
- HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site (2018) (0)
- Crystal Structure of Human Cytochrome P450 CYP46A1 with Posaconazole Bound (2014) (0)
- Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole (2011) (0)
- Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-7 DMPC Bicelle (2013) (0)
- Structure of thereduced HiPIP from thermochromatium tepidum at 0.95 angstrom resolution (2006) (0)
- Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole (2003) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus (2014) (0)
- Aconitase: An Iron-Sulfur Enzyme (1993) (0)
- ABA does not affect topology of pLI. (2004) (0)
- 7-FE FERREDOXIN FROM AZOTOBACTER VINELANDII LOW TEMPERATURE, 1.35 A (1997) (0)
- Human Cytochrome P450 2D6 Quinidine Complex (2015) (0)
- Human Cytochrome P450 2D6 Thioridazine Complex (2015) (0)
- HIV-1 Protease NL4-3 6X mutant (2006) (0)
- Studies on aconitase by spectroscopy, crystallography and mutagenesis (1991) (0)
- Crystal structure of a cytochrome P450 2A6 in complex with a monoterpene - sabinene. (2015) (0)
- S642A:ISOCITRATE COMPLEX OF ACONITASE (1999) (0)
- Mechanism of transhydrogenase coupling proton translocation and hydride transfer (2014) (0)
- HIV Protease (PR) with TL-3 in active site and 4-methylbenzene-1,2-diamine in exosite (2018) (0)
- Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound (2005) (0)
- Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme (2004) (0)
- 7-FE FERREDOXIN FROM AZOTOBACTER VINELANDII AT 100K, NA DITHIONITE REDUCED AT PH 8.5, RESOLUTION 1.4 A (1998) (0)
- Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation (2010) (0)
- STRUCTURE OF GREEN ABALONE LYSIN DIMER (2000) (0)
- Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus (2012) (0)
- PAPS reductase in a covalent complex with thioredoxin C35A (2007) (0)
- Parallel Configuration of pLI E20S (2006) (0)
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