Carl E. Frasch
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Carl E. Fraschbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Chemistry Biology
Carl E. Frasch's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)Carl E. Frasch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. (1982) (3053)
- Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes. (1985) (499)
- Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group (1997) (402)
- Intercontinental spread of a genetically distinctive complex of clones of Neisseria meningitidis causing epidemic disease. (1986) (328)
- Enzyme-Linked Immunosorbent Assay for Quantitation of Human Antibodies to Pneumococcal Polysaccharides (2003) (323)
- Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer (2005) (306)
- Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines (2010) (306)
- Pneumococcal Type 22F Polysaccharide Absorption Improves the Specificity of a Pneumococcal-Polysaccharide Enzyme-Linked Immunosorbent Assay (2001) (301)
- Standardization and a Multilaboratory Comparison ofNeisseria meningitidisSerogroup A and C Serum Bactericidal Assays (1997) (297)
- Description and Nomenclature of Neisseria meningitidis Capsule Locus (2013) (265)
- Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern (1987) (265)
- Use of Opsonophagocytosis for Serological Evaluation of Pneumococcal Vaccines (2006) (197)
- Immune response of Brazilian children to a Neisseria meningitidis serogroup B outer membrane protein vaccine: comparison with efficacy (1994) (192)
- Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease. (2009) (185)
- Five structural classes of major outer membrane proteins in Neisseria meningitidis (1981) (172)
- Multicenter comparison of Neisseria meningitidis serogroup C anti-capsular polysaccharide antibody levels measured by a standardized enzyme-linked immunosorbent assay (1994) (168)
- Vaccines for prevention of meningococcal disease (1989) (166)
- Development of natural immunity to Neisseria meningitidis. (2001) (159)
- Structural characterization of the lipid A component of pathogenic Neisseria meningitidis (1992) (153)
- Classification of Neisseria meningitidis Group B into Distinct Serotypes I. Serological Typing by a Microbactericidal Method (1972) (152)
- Level of maternal IgG anti-group B streptococcus type III antibody correlated with protection of neonates against early-onset disease caused by this pathogen. (2004) (138)
- Effect of O Acetylation of Neisseria meningitidis Serogroup A Capsular Polysaccharide on Development of Functional Immune Responses (2002) (124)
- Lipopolysaccharide (LPS) from Brucella abortus is less toxic than that from Escherichia coli, suggesting the possible use of B. abortus or LPS from B. abortus as a carrier in vaccines (1992) (122)
- AN OUTER MEMBRANE PROTEIN OF NEISSERIA MENINGITIDIS GROUP B RESPONSIBLE FOR SEROTYPE SPECIFICITY (1974) (120)
- Level of maternal antibody required to protect neonates against early-onset disease caused by group B Streptococcus type Ia: a multicenter, seroepidemiology study. (2001) (119)
- Development of a group A meningococcal conjugate vaccine, MenAfriVacTM (2012) (112)
- Preparation of bacterial polysaccharide-protein conjugates: analytical and manufacturing challenges. (2009) (105)
- Ongoing group B Neisseria meningitidis epidemic in São Paulo, Brazil, due to increased prevalence of a single clone of the ET-5 complex (1992) (101)
- Multicenter comparison of levels of antibody to the Neisseria meningitidis group A capsular polysaccharide measured by using an enzyme-linked immunosorbent assay (1992) (99)
- Adherence of isolates of Neisseria meningitidis from patients and carriers to human buccal epithelial cells. (1980) (94)
- High burden of invasive Streptococcus agalactiae disease in South African infants (2003) (92)
- Heterogeneity and variation among Neisseria meningitidis lipopolysaccharides (1983) (90)
- Proposed Standardization of Neisseria meningitidis PorA Variable-Region Typing Nomenclature (1998) (90)
- Protection against group B meningococcal disease. III. Immunogenicity of serotype 2 vaccines and specificity of protection in a guinea pig model (1978) (88)
- Protection against group B Neisseria meningitidis disease: preparation of soluble protein and protein-polysaccharide immunogens (1982) (84)
- Outer membrane protein vesicle vaccines for meningococcal disease. (2001) (80)
- Phylogenetic Lineages of Invasive and Colonizing Strains of Serotype III Group B Streptococci from Neonates: a Multicenter Prospective Study (2006) (79)
- Correlates of immunity for pneumococcal conjugate vaccines. (2003) (78)
- Classification of Neisseria meningitidis group B into distinct serotypes. 3. Application of a new bactericidal-inhibition technique to distribution of serotypes among cases and carriers. (1973) (77)
- Evaluation of Previously Assigned Antibody Concentrations in Pneumococcal Polysaccharide Reference Serum 89SF by the Method of Cross-Standardization (1998) (77)
- Expression of Neisseria meningitidis iron-regulated outer membrane proteins, including a 70-kilodalton transferrin receptor, and their potential for use as vaccines (1990) (76)
- Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines (2010) (75)
- Correlation between Serological and Sequencing Analyses of the PorB Outer Membrane Protein in the Neisseria meningitidis Serotyping System (1998) (74)
- Meningococcal Disease in the United States—1986 (1991) (74)
- Specificity of antibodies to O-acetyl-positive and O-acetyl-negative group C meningococcal polysaccharides in sera from vaccinees and carriers (1991) (74)
- Multilaboratory Evaluation of a Viability Assay for Measurement of Opsonophagocytic Antibodies Specific to the Capsular Polysaccharides of Streptococcus pneumoniae (2003) (71)
- Class-specific antibody response to group B Neisseria meningitidis capsular polysaccharide: use of polylysine precoating in an enzyme-linked immunosorbent assay (1982) (71)
- Serogroup identification of Neisseria meningitidis: comparison of an antiserum agar method with bacterial slide agglutination (1978) (71)
- Immunotype epitopes of Neisseria meningitidis lipooligosaccharide types 1 through 8 (1987) (70)
- Preparation and characterization of an immunogenic meningococcal group A conjugate vaccine for use in Africa. (2009) (67)
- Characterization of Antibodies to Capsular Polysaccharide Antigens of Haemophilus influenzae Type b and Streptococcus pneumoniae in Human Immune Globulin Intravenous Preparations (2004) (67)
- Evaluation of Pneumococcal Polysaccharide Immunoassays Using a 22F Adsorption Step with Serum Samples from Infants Vaccinated with Conjugate Vaccines (2009) (66)
- Pneumococcal Capsular Polysaccharide Preparations May Contain Non-C-Polysaccharide Contaminants That Are Immunogenic (1999) (65)
- Classification of Neisseria meningitidis Group B into Distinct Serotypes II. Extraction of Type-Specific Antigens for Serotyping by Precipitin Techniques (1972) (65)
- Heat-modifiable outer membrane proteins of Neisseria meningitidis and their organization within the membrane (1978) (62)
- Strain-specific variation in the protein and lipopolysaccharide composition of the group B meningococcal outer membrane (1976) (60)
- Protection against group B meningococcal disease. I. Comparison of group-specific and type-specific protection in the chick embryo model (1976) (59)
- Class-specific human bactericidal antibodies to capsular and noncapsular surface antigens of Neisseria meningitidis. (1984) (59)
- Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines (1997) (56)
- Antibody response of adults to an aluminum hydroxide-adsorbed Neisseria meningitidis serotype 2b protein-group B polysaccharide vaccine. (1988) (54)
- Prophylaxis against Neisseria meningitidis infections and antibody responses in patients with deficiency of the sixth component of complement. (1990) (53)
- Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage. (1989) (53)
- An analytical model applied to a multicenter pneumococcal enzyme-linked immunosorbent assay study. (2000) (52)
- Role of protein serotype antigens in protection against disease due to Neisseria meningitidis. (1977) (52)
- Genetic relationships and clonal population structure of serotype 2 strains of Neisseria meningitidis (1987) (48)
- Detection and quantitation of the glucuronoxylomannan-like polysaccharide antigen from clinical and nonclinical isolates of Trichosporon beigelii and implications for pathogenicity (1995) (46)
- Interlaboratory study evaluating quantitation of antibodies to Haemophilus influenzae type b polysaccharide by enzyme-linked immunosorbent assay (1996) (46)
- Meningococcal colonization and infection in children and their household contacts. (1979) (44)
- Protection against group B meningococcal disease: evaluation of serotype 2 protein vaccines in a mouse bacteremia model (1979) (43)
- Analysis of Neisseria meningitidis class 3 outer membrane protein gene variable regions and type identification using genetic techniques (1995) (43)
- Sodium dodecyl sulfate-polyacrylamide gel typing system for characterization of Neisseria meningitidis isolates (1982) (43)
- Development of a Neisseria meningitidis group B serotype 2b protein vaccine and evaluation in a mouse model (1984) (41)
- Chemical Analysis of Major Outer Membrane Proteins of Neisseria meningitidis: Comparison of Serotypes 2 and 11 (1980) (41)
- Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys (1997) (41)
- Amplification of rDNA loci to detect and type Neisseria meningitidis and other eubacteria. (1993) (40)
- Emergence of a new clone of serogroup C Neisseria meningitidis in São Paulo, Brazil (1992) (39)
- Capsular serotype of Staphylococcus aureus in the era of community-acquired MRSA. (2011) (39)
- An Analytical Model Applied to a Multicenter Pneumococcal Enzyme-Linked Immunosorbent Assay Study (2000) (37)
- Analysis of damage to human ciliated nasopharyngeal epithelium by Neisseria meningitidis (1986) (37)
- Diagnostic value of interactions between members of the family Neisseriaceae and lectins (1984) (37)
- A method for purification of bacterial R-type lipopolysaccharides (lipooligosaccharides). (1987) (36)
- Outer membrane proteins of Neisseria meningitidis: structure and importance in meningococcal disease. (1986) (36)
- Quantitation of human IgG subclass antibodies to Haemophilus influenzae type b capsular polysaccharide. Results of an international collaborative study using enzyme immunoassay methodology. (1992) (35)
- Role of lipopolysaccharide in wheat germ agglutinin-mediated agglutination of Neisseria meningitidis and Neisseria gonorrhoeae (1980) (35)
- Capsular polysaccharide-protein conjugate vaccines of carbotype 1 Vibrio vulnificus: construction, immunogenicity, and protective efficacy in a murine model (1995) (35)
- Risk factors for carriage of meningococcus in the Los Angeles County men's jail system. (1991) (34)
- Production and control of Neisseria meningitidis vaccines. (1990) (32)
- Rapid serogroup identification of Neisseria meningitidis by using antiserum agar: Prevalence of serotypes in a disease-free military population (1979) (31)
- Natural bactericidal activity of human serum against Neisseria meningitidis isolates of different serogroups and serotypes (1982) (30)
- Immunogenicity in mice of pneumococcal glycoconjugate vaccines using pneumococcal protein carriers. (2001) (30)
- The immunogenicity of Haemophilus influenzae type b conjugate vaccines in children born to human immunodeficiency virus-infected women. Women and Infants Transmission Study Group. (1998) (29)
- Protective Immunity of Pneumococcal Glycoconjugates (2003) (29)
- Human opsonins to meningococci after vaccination (1984) (29)
- Estimation of Group B Streptococcus Type III Polysaccharide-Specific Antibody Concentrations in Human Sera Is Antigen Dependent (1998) (27)
- Characterization and immunogenicity of meningococcal group C conjugate vaccine prepared using hydrazide-activated tetanus toxoid. (2007) (27)
- Inhibition Enzyme-Linked Immunosorbent Assay for Serotyping of Group B Streptococcal Isolates (1999) (27)
- Comparison of Neisseria meningitidis serogroup W135 polysaccharide-tetanus toxoid conjugate vaccines made by periodate activation of O-acetylated, non-O-acetylated and chemically de-O-acetylated polysaccharide. (2007) (27)
- Recent developments in Neisseria meningitidis group A conjugate vaccines (2005) (26)
- Meningococcal group B vaccine trial in Norway 1981--1982. Preliminary report of results available November 1982. (1983) (25)
- Protection against group B meningococcal disease. II. Infection and resulting immunity in a guinea pig model (1978) (24)
- Involvement of phospholipid end groups of group C Neisseria meningitidis and Haemophilus influenzae type b polysaccharides in association with isolated outer membranes and in immunoassays (1994) (24)
- Immunization against Neisseria meningitidis (1983) (23)
- SAFETY OF VACCINES CONTAINING MENINGOCOCCAL GROUP B POLYSACCHARIDE (1984) (22)
- Strains of Neisseria meningitidis isolated from patients and their close contacts (1982) (22)
- Meningococcal disease in the United States--1986. Meningococcal Disease Study Group. (1991) (22)
- Meningococcal disease caused by Neisseria meningitidis serogroup B serotype 4 in São Paulo, Brazil, 1990 to 1996. (1998) (21)
- Development and Evaluation of Pneumococcal Conjugate Vaccines: Clinical Trials and Control Tests (2002) (20)
- Intercontinental spread of Neisseria meningitidis clones of the ET-5 complex (2004) (20)
- Immunization with meningococcal outer-membrane protein vesicles containing lipooligosaccharide protects mice against lethal experimental group B Neisseria meningitidis infection and septic shock. (1999) (20)
- Protection against group B Neisseria meningitidis disease: effect of serogroup B polysaccharide and polymyxin B on immunogenicity of serotype protein preparations (1982) (19)
- Quantification of bacterial polysaccharides by the purpald assay: measurement of periodate-generated formaldehyde from glycol in the repeating unit. (2001) (18)
- An ELISA study of the antibody response after vaccination with a combined meningococcal group B polysaccharide and serotype 2 outer membrane protein vaccine. (1983) (18)
- Effect of a booster dose of serogroup B meningococcal vaccine on antibody response to Neisseria meningitidis in mice vaccinated with different immunization schedules. (2005) (18)
- Evaluation of the antiserum agar method for the serogroup identification of Neisseria meningitidis. (1979) (18)
- Morphological differences in Neisseria meningitidis pili (1988) (17)
- Lot-release criteria, postlicensure quality control, and the Haemophilus influenzae type b conjugate vaccines. (1995) (16)
- Classification of Neisseria meningitidis Group B into Distinct Serotypes IV. Preliminary Chemical Studies on the Nature of the Serotype Antigen (1972) (15)
- Outer membrane vesicles (OMVs) and detoxified lipooligosaccharide (dLOS) obtained from Brazilian prevalent N. meningitidis serogroup B strains protect mice against homologous and heterologous meningococcal infection and septic shock. (2004) (15)
- Immune response to native NadA from Neisseria meningitidis and its expression in clinical isolates in Brazil. (2003) (15)
- Status of a group B Neisseria meningitidis vaccine. (1985) (15)
- Specificity of Human Antibodies Reactive with Pneumococcal C Polysaccharide (2000) (15)
- Characterization of a stress protein from group B Neisseria meningitidis (1993) (14)
- Outer membrane antigens of Neisseria meningitidis group B serotype 2 studied by crossed immunoelectrophoresis (1979) (13)
- Monoclonal antibody to serotype 17 of Neisseria meningitidis and their prevalence in Brazilian states. (1995) (13)
- Serotypes and polyacrylamide gel electrophoresis types among disease-associated isolates of group B Neisseria meningitidis in Spain, 1976-1979. (1983) (13)
- Technical Development of a New Meningococcal Conjugate Vaccine (2015) (13)
- Spectrum of disease due to Haemophilus influenzae type b occurring in vaccinated children. (1988) (12)
- Prospects for the prevention of meningococcal disease: special reference to group B. (1987) (12)
- Clinical characteristics of a novel 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine candidate (PHiD-CV). Introduction. (2009) (11)
- Seroepidemiologic aspects of Neisseria meningitidis in homosexual men. (1982) (11)
- Lessons Learned and Future Challenges in the Design and Manufacture of Glycoconjugate Vaccines (2018) (11)
- Meningitis caused by a nonencapsulated strain of Neisseria meningitidis in twin infants with a C6 deficiency. (1987) (9)
- Human immune response to epitopes on the meningococcal outer membrane class 5 protein following natural infection. (1996) (8)
- Re-emergence of meningococcal carriage on three-year follow-up of a kibbutz population after whole-community chemoprophylaxis (1993) (8)
- Serogroup Identification ofNeisseria meningitidis: Comparison ofanAntiserum AgarMethodwithBacterial Slide Agglutination (1978) (7)
- Genetic and immunologic characterization of a novel serotype 4, 15 strain of Neisseria meningitidis. (2000) (7)
- Binding diversity of monoclonal antibodies to alpha(2-->8) polysialic acid conjugated to outer membrane vesicle via adipic acid dihydrazide. (1996) (7)
- Meningococcal disease in Alabama. (1978) (7)
- Serogroup and serotype classification of bacterial pathogens. (1994) (6)
- Haemophilus b disease after vaccination with Haemophilus b polysaccharide or conjugate vaccine. (1991) (6)
- Antibody Response to Meningococcal Infection in Late Complement Component Deficient Individuals (1991) (6)
- Induction of iron regulated proteins during normal growth of Neisseria meningitidis in a chemically defined medium. (1994) (6)
- Antibody response to infection in multiple myeloma. Implications for vaccination. (1979) (5)
- Immunogenic and protective properties of meningococcal serotype 2a protein in the hen-embryo model. (1983) (5)
- Antibody studies in mice of outer membrane antigens for use in an improved meningococcal B and C vaccine. (1996) (5)
- Appearance of new strains associated with group B meningococcal disease and their use for rapid vaccine development (2004) (4)
- Immune response to meningococcal serogroup B polysaccharide and serotype 2a outer membrane complex vaccines (1988) (4)
- Genetic Relationships andClonal Population Structure ofSerotype 2 Strains ofNeisseria meningitidis (1987) (3)
- The use of oligonucleotide probes for meningococcal serotype characterization. (1998) (3)
- Neisseria meningitidis Vaccines (2003) (3)
- Surface antigen analysis of group B Neisseria meningitidis outer membrane by monoclonal antibodies: Identification of bactericidal antibodies to class 5 protein (1995) (3)
- Development of a second generation group B meningococcal vaccine. (1991) (3)
- Immunologic and genetic characterization of lipooligosaccharide variants in a Neisseria meningitidis serogroup C strain. (2002) (3)
- A comparison of the serum agar grouping and slide agglutination methods for the identification of Neisseria meningitidis strains. (1977) (3)
- Serogroup identification of meningococci by a modified antiserum agar method (1979) (3)
- Invasive meningococcal disease: secondary spread in a day-care center. (1989) (2)
- Analysis and Characterization of Bacterial Endotoxins (Lipopolysaccharides) by SDS-Polyacrylamide Gel Electrophoresis Followed by Silver Stain (1986) (2)
- Human immune response to an aluminum hydroxide absorbedNeisseria meningitidis serotype 2b protein vaccine (1986) (2)
- Immunogenicity of lipopolysaccharide derived from Brucella abortus: potential as a carrier in development of vaccines for AIDS. (1991) (2)
- Immune Responses to Polysaccharide and Conjugate Vaccines (2006) (2)
- Chemoprophylactic Suppression of Endemic Carriage of Group B Serotype 4 Neisseria meningitidis in a Kibbutz Community (1991) (2)
- Identification of a disease-associated serotype common to meningococcus groups B, C, Y and 135 W. (1977) (2)
- Preliminary results from a clinical trail with a meningococcal vaccine containing serotype 2b and 15 antigens in complex with mixed A, C, Y and W135 polysaccharides (1986) (2)
- juvenile rhesus monkeys. polysaccharide-protein conjugate vaccines in meningitidis and Escherichia coli K92 capsular Preclinical evaluation of group B Neisseria (2013) (1)
- Meningitis caused by a nonencapsulated strain of neisseria meningitidis in twin infants with complement c 6 deficiency (1986) (1)
- Status of a group BNeisseria meningitidis vaccine (1985) (1)
- Induction of group 17 specific antibodies by pneumococcal type 17F and 17A polysaccharide vaccines. (2001) (1)
- MENINGOCOCCAL VACCINES AND DISEASE DUE TO OTHER SEROGROUPS (1978) (1)
- Characterization ofa Stress Protein fromGroupB Neisseria meningitidis (1993) (1)
- efficacy in a murine model . construction , immunogenicity , and protective vaccines of carbotype 1 Vibrio vulnificus : Capsular polysaccharide-protein conjugate (1995) (0)
- MENINGOCOCCAL LIPOPOLYSACCHARIDES fore , sugar composition analyses of LPS based on immunotypes (2003) (0)
- Development ofa Neisseria meningitidis GroupB Serotype 2b Protein Vaccine andEvaluation ina MouseModel (1984) (0)
- Structural Orientation and Antigenic Analysis of the Class 2 and Class 3 Outer Membrane Proteins of Neisseria meningitidis (1991) (0)
- Effect of a booster dose of serogroup B meningococcal vaccine on antibody response to Neisseria meningitidis in mice vaccinated with different immunization schedules (2005) (0)
- Procede de preparation de vaccins conjugues polyssacharide-proteine (2004) (0)
- polysaccharide-protein conjugate vaccines. Neisseria meningitidis capsular rhesus monkeys immunized with group B Bactericidal antibody responses of juvenile (2013) (0)
- Longitudinal studies of miningococcal carriage during a groupe B epidemic (1983) (0)
- The emerging epidemic of meningococcal disease in N. W. Europe, International Symposium, held in Amsterdam, May 1985 (1987) (0)
- Results of a Phase I/II Randomized Immunotherapy Trial Testing Adoptive Transfer of Co-Stimulated Autologous T Cells and Pneumococcal Conjugate Vaccine (PCV) Immunization after Autotransplantation for Myeloma (MM). (2004) (0)
- The conjugation method influences the immunogenicity of Streptococcus pneumoniae 19F conjugate vaccine (2010) (0)
- or LPS from B. abortus as a carrier in vaccines. coli, suggesting the possible use of B. abortus Escherichia abortus is less toxic than that from Lipopolysaccharide (LPS) from Brucella (2014) (0)
- Development ofNeisseria meningitidis serotype 15 protein/polysaccharide vaccine and evaluation in a mouse model (1986) (0)
- Analytical and Manufacturing Challenges in Preparation of Bacterial Polysaccharide Conjugates (2008) (0)
- Analysi so fGen eExpressio ni nth eRat Hippocampu sUsin gRea lTim ePC RReveals Hig hInter-Individua lVariatio ni nmRNA Expressio nLevels (2002) (0)
- Specificity of Antibody response to Group C meningococcal Polysaccharide among vaccinees and carriers (1991) (0)
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What Schools Are Affiliated With Carl E. Frasch?
Carl E. Frasch is affiliated with the following schools:
