Charles E. Samuel
#120,319
Most Influential Person Now
Charles E. Samuel's AcademicInfluence.com Rankings
Charles E. Samuelphilosophy Degrees
Philosophy
#5428
World Rank
#8222
Historical Rank
Logic
#2714
World Rank
#3744
Historical Rank
Charles E. Samuelbiology Degrees
Biology
#7254
World Rank
#10148
Historical Rank
Virology
#152
World Rank
#157
Historical Rank
Biochemistry
#989
World Rank
#1101
Historical Rank
Download Badge
Philosophy Biology
Charles E. Samuel's Degrees
- PhD Biochemistry Stanford University
- Doctorate Medicine Harvard University
Why Is Charles E. Samuel Influential?
(Suggest an Edit or Addition)Charles E. Samuel's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Antiviral Actions of Interferons (2001) (2708)
- Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. (1991) (608)
- Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase (1995) (480)
- Dynamic landscape and regulation of RNA editing in mammals (2017) (384)
- The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans. (1993) (373)
- Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase (1986) (327)
- The role of gamma interferon in antimicrobial immunity. (2001) (326)
- cDNA structures and regulation of two interferon-induced human Mx proteins (1989) (320)
- Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral. (2011) (276)
- Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible. (1999) (272)
- Mechanism of interferon action: phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase. (1979) (226)
- Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA‐dependent protein kinase PKR (1997) (224)
- A standardized nomenclature for adenosine deaminases that act on RNA. (1997) (220)
- Three-dimensional imaging of lipid gene-carriers: membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes. (2003) (203)
- RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis (2010) (169)
- Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase. (1992) (167)
- Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level. (2004) (166)
- Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. (2012) (164)
- Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons. (1995) (161)
- New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid–DNA complexes for gene delivery (2005) (159)
- HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR. (1995) (158)
- Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells. (1996) (156)
- Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA. (2007) (139)
- Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR (1993) (138)
- Functionally Distinct Double-stranded RNA-binding Domains Associated with Alternative Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase* (1997) (137)
- RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR* (2009) (131)
- Cationic liposome-nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA. (2010) (130)
- Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. (1985) (130)
- Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase. (1994) (124)
- A protein synthesizing system from interferon-treated cells that discriminates between cellular and viral messenger RNAs. (1974) (117)
- Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response. (2011) (115)
- Mechanism of interferon action: cDNA structure, expression, and regulation of the interferon-induced, RNA-dependent P1/eIF-2 alpha protein kinase from human cells. (1992) (111)
- Expression of Interferon-inducible RNA Adenosine Deaminase ADAR1 during Pathogen Infection and Mouse Embryo Development Involves Tissue-selective Promoter Utilization and Alternative Splicing* (2005) (110)
- The RNA-activated Protein Kinase Enhances the Induction of Interferon-β and Apoptosis Mediated by Cytoplasmic RNA Sensors* (2009) (103)
- Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. (1998) (103)
- Characterization of the 5'-flanking region of the human RNA-specific adenosine deaminase ADAR1 gene and identification of an interferon-inducible ADAR1 promoter. (1999) (101)
- Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses* (2016) (101)
- Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1 (2012) (101)
- Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase. (2006) (97)
- Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles (2019) (97)
- Adenosine deaminases acting on RNA, RNA editing, and interferon action. (2011) (96)
- Protein Kinase PKR Plays a Stimulus- and Virus-Dependent Role in Apoptotic Death and Virus Multiplication in Human Cells (2007) (94)
- Serotonin-2C Receptor Pre-mRNA Editing in Rat Brain andin Vitro by Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1* (1999) (93)
- The PKR protein kinase--an interferon-inducible regulator of cell growth and differentiation. (1997) (90)
- Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses (2019) (90)
- Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells. (1992) (90)
- Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5'-flanking region of human and mouse Pkr genes. (1997) (84)
- Mechanisms of the antiviral action of interferons. (1988) (82)
- Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis (2007) (81)
- ADARs: viruses and innate immunity. (2012) (80)
- Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus (2009) (79)
- Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoter. (2000) (78)
- RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment. (2010) (78)
- Mechanism of interferon action. Activation of the human P1/eIF-2 alpha protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA. (1989) (77)
- Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase (1996) (77)
- Mechanism of interferon action. Increased phosphorylation of protein synthesis initiation factor eIF-2 alpha in interferon-treated, reovirus-infected mouse L929 fibroblasts in vitro and in vivo. (1984) (77)
- Structure and Structure—Function Studies of Lipid/Plasmid DNA Complexes (2000) (75)
- Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity. (1994) (74)
- Proteolytic cleavage of the reovirus sigma 3 protein results in enhanced double-stranded RNA-binding activity: identification of a repeated basic amino acid motif within the C-terminal binding region (1992) (73)
- Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase (1995) (72)
- Mechanism of interferon action. Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts. (1985) (72)
- Editing of Glutamate Receptor Subunit B Pre-mRNA by Splice-site Variants of Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1* (1999) (71)
- Induction of Protein Kinase PKR-dependent Activation of Interferon Regulatory Factor 3 by Vaccinia Virus Occurs through Adapter IPS-1 Signaling* (2008) (71)
- Protein Kinase PKR Mediates the Apoptosis Induction and Growth Restriction Phenotypes of C Protein-Deficient Measles Virus (2008) (71)
- Measles Virus C Protein Impairs Production of Defective Copyback Double-Stranded Viral RNA and Activation of Protein Kinase R (2013) (69)
- Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity. (2001) (69)
- Protein Kinase PKR Amplification of Interferon β Induction Occurs through Initiation Factor eIF-2α-mediated Translational Control* (2012) (68)
- Measles Virus Defective Interfering RNAs Are Generated Frequently and Early in the Absence of C Protein and Can Be Destabilized by Adenosine Deaminase Acting on RNA-1-Like Hypermutations (2015) (68)
- An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1). (2014) (64)
- Mechanism of interferon action. Kinetics of interferon action in mouse L929 cells: translation inhibition, protein phosphorylation, and messenger RNA methylation and degradation. (1977) (63)
- Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications (2006) (63)
- Adenosine Deaminase Acting on RNA 1 (ADAR1) Suppresses the Induction of Interferon by Measles Virus (2012) (62)
- The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2. (1995) (60)
- Evidence against the folate-mediated formylation of formyl-accepting methionyl transfer ribonucleic acid in Streptococcus faecalis R. (1970) (60)
- Reoviruses and the interferon system. (1998) (57)
- Biosynthesis of reovirus-specified polypeptides: the reovirus s1 mRNA encodes two primary translation products. (1985) (57)
- Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR. (2000) (56)
- PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon. (1993) (55)
- Adenovirus VAI RNA antagonizes the RNA-editing activity of the ADAR adenosine deaminase. (1998) (54)
- Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5'-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon. (2008) (53)
- Activation of NF-kappaB-dependent gene expression by Salmonella flagellins FliC and FljB. (2007) (52)
- PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus. (2001) (51)
- Structural organization of the human gene (PKR) encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog. (1996) (49)
- Mechanism of Interferon Action: Identification of Essential Positions within the Novel 15-Base-Pair KCS Element Required for Transcriptional Activation of the RNA-Dependent Protein Kinasepkr Gene (1998) (48)
- Tissue Selectivity of Interferon-Stimulated Gene Expression in Mice Infected with Dam+ versus Dam−Salmonella enterica Serovar Typhimurium Strains (2002) (47)
- Host genetic variability and West Nile virus susceptibility (2002) (47)
- Mechanism of interferon action: RNA-binding activity of full-length and R-domain forms of the RNA-dependent protein kinase PKR--determination of KD values for VAI and TAR RNAs. (1995) (46)
- Protein Kinase PKR-Dependent Activation of Mitogen-Activated Protein Kinases Occurs through Mitochondrial Adapter IPS-1 and Is Antagonized by Vaccinia Virus E3L (2009) (46)
- Biosynthesis of reovirus-specified polypeptides. Initiation of reovirus messenger RNA translation in vitro and identification of methionyl-x initiation peptides. (1977) (46)
- Detection of in vivo synthesis of polycistronic mRNAs of vesicular stomatitis virus. (1984) (44)
- NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR (2016) (42)
- Mechanism of interferon action: functional characterization of positive and negative regulatory domains that modulate transcriptional activation of the human RNA-dependent protein kinase Pkr promoter. (1999) (42)
- RNA Editing Minireview Series* (2003) (41)
- Two-dimensional packing of short DNA with nonpairing overhangs in cationic liposome-DNA complexes: from Onsager nematics to columnar nematics with finite-length columns. (2011) (41)
- Activation of the RNA-dependent Protein Kinase PKR Promoter in the Absence of Interferon Is Dependent Upon Sp Proteins* (2006) (41)
- The PKR kinase promoter binds both Sp1 and Sp3, but only Sp3 functions as part of the interferon-inducible complex with ISGF-3 proteins. (2003) (40)
- Mechanism of interferon action. Characterization of sites of phosphorylation in the interferon-induced phosphoprotein P1 from mouse fibroblasts: evidence for two forms of P1. (1982) (39)
- Mechanism of interferon action. Properties of an interferon-mediated ribonucleolytic activity from mouse L929 cells. (1978) (39)
- Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human leukocyte interferon. II. Effect on viral macromolecular synthesis. (1983) (38)
- Mechanism of interferon action. cDNA structure and regulation of a novel splice-site variant of the catalytic subunit of human protein kinase A from interferon-treated human cells. (1992) (37)
- Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2). (2002) (37)
- Adenosine deaminase ADAR1 increases gene expression at the translational level by decreasing protein kinase PKR-dependent eIF-2alpha phosphorylation. (2009) (37)
- Protein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection. (2012) (37)
- Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase. (1996) (36)
- Detection of subnanogram amounts of RNA in polyacrylamide gels in the presence and absence of protein by staining with silver. (1982) (36)
- Mechanism of interferon action. Species specificity of interferon and of the interferon-mediated inhibitor of translation from mouse, monkey, and human cells. (1977) (36)
- Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products. (2009) (36)
- Biosynthesis of reovirus-specified polypeptides. purification and characterization of the small-sized class mRNAs of reovirus type 3: coding assignments and translational efficiencies. (1980) (35)
- Mechanism of interferon action. The interferon-induced phosphoprotein P1 possesses a double-stranded RNA-dependent ATP-binding site. (1985) (35)
- Mechanism of interferon action: human leukocyte and immune interferons regulate the expression of different genes and induce different antiviral states in human amnion U cells. (1983) (34)
- Purification of double-stranded RNA-dependent protein kinase from mouse fibroblasts. (1986) (31)
- Mechanism of interferon action. Kinetics of interferon action in mouse L929 cells: phosphorylation of protein synthesis initiation factor elF-2 and ribosome-associated protein P1. (1979) (30)
- Biosynthesis of reovirus-specified polypeptides. Effect of methylation on the efficiency of reovirus genome expression in vitro. (1977) (29)
- Mechanism of interferon action: synthesis and activity of the interferon-mediated low-molecular-weight oligonucleotide from murine and human cells. (1979) (29)
- Mechanism of interferon action. Effect of double-stranded RNA and the 5'-O-monophosphate form of 2',5'-oligoadenylate on the inhibition of reovirus mRNA translation in vitro. (1983) (29)
- A comparison of transfer RNA from untreated and interferon-treated murine cells. (1976) (28)
- Biosynthesis of reovirus-specified polypeptides: expression of reovirus S1-encoded sigma 1NS protein in transfected and infected cells as measured with serotype specific polyclonal antibody. (1991) (28)
- Double-stranded RNA-specific adenosine deaminase: nucleic acid binding properties. (1998) (27)
- Knockdown by RNAi—proceed with caution (2004) (27)
- Biosynthesis of reovirus-specified polypeptides: ribosome pausing during the translation of reovirus S1 mRNA. (1992) (27)
- Mechanism of interferon action. Interferon-mediated inhibition of simian virus-40 early RNA accumulation. (1980) (27)
- Biosynthesis of reovirus-specified polypeptides. Multiplication rate but not yield of reovirus serotypes 1 and 3 correlates with the level of virus-mediated inhibition of cellular protein synthesis. (1984) (27)
- Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R. Biochemical and biophysical properties of methionine transfer ribonucleic acid. (1974) (26)
- Biosynthesis of reovirus-specified polypeptides. The s1 mRNA synthesized in vivo is structurally and functionally indistinguishable from in vitro-synthesized s1 mRNA and encodes two polypeptides, sigma 1a and sigma 1bNS. (1985) (26)
- Polycistronic Animal Virus mRNAs (1989) (26)
- Mechanism of interferon action. Interferon-mediated inhibition of reovirus mRNA translation in the absence of detectable mRNA degradation but in the presence of protein phosphorylation. (1980) (25)
- Mechanism of interferon action. Kinetics of decay of the antiviral state and protein phosphorylation in mouse fibroblasts treated with natural and cloned interferons. (1982) (25)
- Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1. (2014) (25)
- Biosynthesis of reovirus-specified polypeptides. Efficiency of expression of cDNAs of the reovirus S1 and S4 genes in transfected animal cells differs at the level of translation. (1987) (24)
- Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain bicistronic s1 mRNA which encodes the minor capsid polypeptide sigma 1a and the nonstructural polypeptide sigma 1bNS. (1986) (23)
- Biosynthesis of reovirus-specified polypeptides: effect of point mutation of the sequences flanking the 5'-proximal AUG initiator codons of the reovirus S1 and S4 genes on the efficiency of mRNA translation. (1988) (22)
- Procedures for measurement of phosphorylation of ribosome-associated proteins in interferon-treated cells. (1981) (22)
- DNA Damage-binding Proteins and Heterogeneous Nuclear Ribonucleoprotein A1 Function as Constitutive KCS Element Components of the Interferon-inducible RNA-dependent Protein Kinase Promoter* (2004) (21)
- Role of the RNA-dependent protein kinase in the regulated expression of genes in transfected cells. (1992) (21)
- forms of the deaminase . deaminase from human cells : evidence for two double-stranded-RNA-specific adenosine Expression and regulation by interferon of a (1995) (21)
- Bass, B. L. et al. A standardized nomenclature for adenosine deaminases that act on RNA. RNA 3, 947-949 (1997) (20)
- Mechanism of interferon action: cloned human leukocyte interferons induce protein kinase and inhibit vesicular stomatitis virus but not reovirus replication in human amnion cells. (1981) (20)
- Regulation of the interferon-inducible PKR kinase gene: the KCS element is a constitutive promoter element that functions in concert with the interferon-stimulated response element. (2002) (20)
- Host Response to Polyomavirus Infection Is Modulated by RNA Adenosine Deaminase ADAR1 but Not by ADAR2 (2011) (19)
- Biosynthesis of reovirus-specified polypeptides. 2-aminopurine increases the efficiency of translation of reovirus s1 mRNA but not s4 mRNA in transfected cells. (1990) (19)
- Methionine transfer ribonucleic acid from folate-sufficient and folate-deficient Streptococcus faecalis R. (1972) (19)
- Upon Infection, Cellular WD Repeat-Containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication (2017) (19)
- Adenosine Deaminases Acting on RNA (ADARs) and Viral Infections. (2021) (18)
- Alternative splice variants of the human PKR protein kinase possessing different 5'-untranslated regions: expression in untreated and interferon-treated cells and translational activity. (1999) (18)
- Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing (2012) (17)
- Translation of virus mRNA: comparison of reovirus and brome mosaic virus single-stranded RNAs in a wheat germ cell-free system. (1975) (17)
- Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor. (1994) (17)
- Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections (2021) (16)
- Interferons, Interferon Receptors, Signal Transducer and Transcriptional Activators, and Interferon Regulatory Factors* (2007) (16)
- Mechanism of interferon action. I. Characterization of a 54-kDa protein induced by gamma interferon with properties similar to a cytoskeletal component. (1987) (16)
- Protein-nucleic acid interactions and cellular responses to interferon. (1998) (16)
- Mechanism of interferon action. Studies on the mechanism of interferon-mediated inhibition of reovirus messenger RNA translation in cell-free protein synthesis systems from mouse ascites tumor cells. (1976) (15)
- Functional analysis of the KCS-like element of the interferon-inducible RNA-specific adenosine deaminase ADAR1 promoter. (2003) (15)
- Mechanism of interferon action. Expression of vesicular stomatitis virus G gene in transfected COS cells is inhibited by interferon at the level of protein synthesis. (1986) (15)
- Mechanism of interferon action. Partial purification and characterization of a low-molecular-weight interferon-mediated inhibitor of translation with nucleolytic activity. (1977) (15)
- MECHANISMS OF INTERFERON‐MEDIATED INHIBITION OF PROTEIN SYNTHESIS * (1980) (15)
- Comparison of Tissue-Selective Proinflammatory Gene Induction in Mice Infected with Wild-Type, DNA Adenine Methylase-Deficient, and Flagellin-Deficient Salmonella enterica (2007) (15)
- Innate Immunity Minireview Series: Making Biochemical Sense of Nucleic Acid Sensors That Trigger Antiviral Innate Immunity* (2007) (15)
- Mechanism of interferon action: ability of cloned human type-alpha interferons to induce protein phosphorylation and inhibit virus replication is specified by the host cell rather than the interferon subspecies. (1982) (14)
- STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1. (2015) (14)
- Mechanism of interferon action. Differential effect of interferon on the synthesis of simian virus 40 and reovirus polypeptides in monkey kidney cells. (1982) (14)
- Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain s2 mRNA which encodes the virion core polypeptide sigma 2. (1987) (13)
- Mechanism of interferon action. Inhibition of vesicular stomatitis virus in human amnion U cells by cloned human leukocyte interferon. (1984) (13)
- Mechanism of interferon action: alpha and gamma interferons differentially affect mRNA levels of the catalytic subunit of protein kinase A and protein Mx in human cells (1992) (13)
- Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5'-flanking region and functional identification of the minimal inducible promoter. (2000) (12)
- Innate interferon response in macrophage and epithelial cells infected with wild-type compared to DNA adenine methylase and flagellin mutant Salmonella enterica serovar Typhimurium. (2007) (12)
- Biosynthesis of reovirus-specified polypeptides: identification of regions of the bicistronic reovirus S1 mRNA that affect the efficiency of translation in animal cells. (1993) (12)
- Interaction of the human protein kinase PKR with the mouse PKR homolog occurs via the N-terminal region of PKR and does not inactivate autophosphorylation activity of mouse PKR. (1997) (12)
- RNA-dependent protein kinase PKR and the Z-DNA binding orthologue PKZ differ in their capacity to mediate initiation factor eIF2α-dependent inhibition of protein synthesis and virus-induced stress granule formation. (2013) (12)
- Virus-Host Interaction Minireview Series: Human Immunodeficiency Virus, Hepatitis C Virus, and Influenza Virus* (2006) (12)
- Biosynthesis of reovirus-specified polypeptides. Analysis of ribosome pausing during translation of reovirus S1 and S4 mRNAs in virus-infected and vector-transfected cells. (1993) (12)
- Assignment1 of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization (2000) (12)
- Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells (2019) (11)
- Initiation of Protein Synthesis by Folate-Sufficient and Folate-Deficient Streptococcus faecalis R: Partial Purification and Properties of Methionyl-Transfer Ribonucleic Acid Synthetase and Methionyl-Transfer Ribonucleic Acid Formyltransferase (1974) (11)
- The promoter-proximal KCS element of the PKR kinase gene enhances transcription irrespective of orientation and position relative to the ISRE element and is functionally distinct from the KCS-like element of the ADAR deaminase Promoter. (2002) (11)
- Sequence of the murine interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones. (1995) (11)
- Mechanism of interferon action: inhibition of pppA(2'p5'A)n-dependent ribonucleases activity in micrococcal nuclease-treated mouse L cell-free extracts. (1981) (11)
- Eucaryotic methionyl transfer ribonucleic acid. Effects of aminoacylation and of formylation on chromatographic behavior. (1973) (11)
- Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain s4 mRNA which encodes the major capsid surface polypeptide sigma 3. (1986) (10)
- Interleukin-1 beta secretion is activated comparably by FliC and FljB flagellins but differentially by wild-type and DNA adenine methylase-deficient salmonella. (2008) (10)
- Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human gamma-interferon. I. Effect on early and late stages of the viral multiplication cycle. (1985) (10)
- Isolation and characterization of a molecular cDNA clone of a human mRNA from interferon-treated cells encoding nucleolar protein B23, numatrin. (1989) (10)
- Mechanism of interferon action sequence of the human interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones. (1996) (10)
- Effect of formylation on the chromatographic behavior of methionyl transfer ribonucleic acid. (1972) (9)
- Mechanism of interferon action. Translational control and the RNA-dependent protein kinase (PKR): antagonists of PKR enhance the translational activity of mRNAs that include a 161 nucleotide region from reovirus S1 mRNA. (1994) (9)
- Mechanism of interferon action. Kinetics of induction of the antiviral state and protein phosphorylation in mouse fibroblasts treated with natural and cloned interferons. (1982) (9)
- Mechanism of interferon action. Production and characterization of monoclonal and polyclonal antibodies to the interferon-induced phosphoprotein P1. (1985) (8)
- Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human gamma-interferon. II. Effect on viral macromolecular synthesis. (1985) (8)
- Lipid–DNA Interactions: Structure–Function Studies of Nanomaterials for Gene Delivery (2007) (8)
- Mechanism of interferon action: interferon inhibits the synthesis of viral proteins and induces protein P1 phosphorylation in both adenylate cyclase-deficient and cAMP-dependent protein kinase-deficient variants of mouse lymphoma cells. (1982) (8)
- Mechanism of interferon action: simian virus 40-specific early polypeptides synthesized in untreated and interferon-treated monkey kidney cells. (1980) (7)
- Biosynthesis of reovirus-specified polypeptides. System-dependent effect of reovirus mRNA methylation on translation in vitro catalyzed by ascites tumor and wheat embryo cell-free extracts. (1977) (7)
- Antiviral and antidifferentiative activities of interferon beta and gamma in relation to their induction of double-stranded RNA-dependent protein kinase activity in 3T3-L1 cells. (1988) (7)
- Mechanism of interferon action: studies on the activation of protein phosphorylation and the inhibition of translation in cell-free systems. (1988) (6)
- Molecular mechanisms of interferon action: interferon-mediated phosphorylation of ribosome-associated protein P1 and protein synthesis initiation factor eIF-2. (1981) (6)
- Thematic Minireview Series: Toward a Structural Basis for Understanding Influenza Virus-Host Cell Interactions* (2010) (5)
- Mechanism of interferon action: stability and translation of simian virus-40 early mRNA coding for T-antigen is comparable in untreated and interferon-treated monkey cells. (1981) (5)
- Interferon-induced proteins and their mechanisms of action. (1994) (5)
- Thematic Minireview Series: Elucidating Hepatitis C Virus-Host Interactions at the Biochemical Level* (2010) (4)
- Induction of interferons and interferon-induced genes (1996) (4)
- Mechanism of Interferon Action : Inhibition of Vesicular Stomatitis Virus Replication in Human Amnion U Cells by Cloned Human Leukocyte Interferon 11 (2001) (4)
- Mechanism of interferon action. II. Induction and decay kinetics of the antiviral state and protein P54 in human amnion U cells treated with gamma interferon. (1987) (4)
- Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human leukocyte interferon. I. Effect on early and late stages of the viral multiplication cycle. (1983) (4)
- Reply to Matthaei et al.: The p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 is required for embryogenesis (2011) (3)
- Poor growth of human adenovirus-12 compared to adenovirus-2 correlates with a failure to impair PKR activation during the late phase of infection. (2015) (3)
- A 3D columnar phase of stacked short DNA organized by coherent membrane undulations. (2019) (3)
- Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain s3 mRNA which encodes the nonstructural RNA-binding protein sigma NS. (1986) (3)
- Mechanism of interferon action: eIF-2 alpha phosphatase in interferon-treated mouse fibroblasts is double-stranded RNA independent. (1982) (3)
- Progress toward the understanding of the molecular mechanisms of interferon action. (1987) (3)
- Mechanism of interferon action. Expression of reovirus S3 gene in transfected COS cells and subsequent inhibition at the level of protein synthesis by type I but not by type II interferon. (1988) (3)
- Introduction to Thematic Minireview Series: Understanding Human Immunodeficiency Virus-Host Interactions at the Biochemical Level* (2012) (2)
- STAT 2-dependent induction of RNA adenosine deaminase ADAR 1 by type I interferon differs between mouse and human cells in the requirement for STAT 1 (2015) (2)
- Mechanism of interferon action. Interferon alpha inhibits vesicular stomatitis virus primary transcript accumulation in P1/eIF-2 alpha protein kinase-deficient human fibroblast cells. (1987) (2)
- NH2-Terminal Amino Acid Distribution and Amino Acid Composition of Streptococcus faecalis R Soluble and Ribosomal Proteins (1973) (2)
- I09 Adenosine deaminae (ADAR1) acting on double-stranded RNA and protein kinase PKR dependent on dsRNA as opposing modulators of antiviral innate immunity (2012) (1)
- Host 5′-3′ Exoribonuclease XRN1 Acts as a Proviral Factor for Measles Virus Replication by Downregulating the dsRNA-Activated Kinase PKR (2022) (1)
- Mechanism of interferon action : Autoregulation of RNA-dependent P 1 / eIF-2 a protein kinase ( PKR ) expression in transfected mammalian cells ( translational control / protein synthesis factor eIF-2 a / kinase phosphotransfer mutant / RNA-binding protein ) (2004) (1)
- Induction of interferons-induced genes. (1996) (1)
- ID: 32: Roles of A-to-I editing by RNA adenosine deaminase ADAR1 in innate immunity RNA sensing (2015) (1)
- 184. Novel Cationic Multivalent Lipids Show Improved Delivery of siRNA and DNA (2006) (1)
- Reply to Steinman and Wang: Involvement of the p150 isoform of the RNA editing enzyme ADAR1 in embryonic lethality (2011) (1)
- CS5-2 Tipping the balance: ADAR1 deaminase and PKR kinase can display opposing roles during viral infection (2010) (0)
- Molecular mechanisms of interferon action phosphorylation of protein p 1 and protein synthesis initiation factor eif 2 alpha in untreated and interferon treated cells (1985) (0)
- Effect of Nucleic Acid Length and Chemistry on Structure-Function Properties of Cationic Lipid-Nucleic Acid Complexes (2009) (0)
- Characterization of the interferon-induced double-stranded RNA-dependent protein kinase and its possible role in the antiviral action of interferon. (1985) (0)
- Mechanism of Interferon Action 11. INDUCTION AND DECAY KINETICS OF THE ANTIVIRAL STATE AND PROTEIN P54 IN HUMAN AMNION (2001) (0)
- Mechanism ofinterferon action: Simianvirus 40-specific early polypeptides synthesized inuntreated andinterferon-treat (1980) (0)
- Contents, Vol. 42, 1975 (1975) (0)
- Subject Index Vol. 89, 2000 (2000) (0)
- Protein Kinase PKR Mediates the Apoptosis Induction and Growth Restriction Phenotypes of C Protein-Deficient Measles Virus (cid:1) (2008) (0)
- Confocal Microscopy Studies of Cationic Lipid/dna Complexes Reveal Distinct Pathways of Gene Delivery in Cells as a Function of Structure (2000) (0)
- Professor A. Grumbach 1895-1975 (1975) (0)
- 771. Complexes of Nucleic Acids with Multivalent Cationic Lipids for the Study of Delivery Pathways and Mechanisms: From Plasmid DNA to siRNA (2005) (0)
- 84. RNA Silencing: Role of Interferon System Components in Non_Specific Effects Induced by Chemically Synthesized Small Interfering RNAs, Enzymatically Synthesized Small Interfering RNAs and Short Hairpin RNAs (2006) (0)
- Procedures for isolation and assay of translation-inhibitory ribosome-associated proteins. (1981) (0)
- S-22 : RNA adenosine deaminase ADAR1 and RNA-dependent protein kinase PKR: Opposing modulators of antiviral innate immunity (2014) (0)
- Contents Vol. 89, 2000 (2000) (0)
- The Effect of Air Traffic Control Experience Levels on Quality of Service. (1979) (0)
- CS03-7 Double-stranded RNA Adenosine Deaminase (ADAR) as a Modulator of Antiviral Innate Immunity (2011) (0)
- Bell Curve for Transfection by Lamellar Cationic Lipid--DNA Complexes (2004) (0)
- RNA Interference Induced by the Cationic Lipid Delivery of siRNA (2005) (0)
- [25] Protein RNA-binding activity measured by northwestern blot analysis: The interferon-inducible RNA-dependent protein kinase PKR (1995) (0)
- Mechanism ofinterferon action: Structure ofthemousePKR gene encoding theinterferon-induc ible (1994) (0)
- The In-Situ Structure of Cationic Lipid/DNA Complexes in Animal Cells: Applications to Gene Therapy (1997) (0)
- Cytokines in the Treatment of Human Disease: The Interferon System—from the Laboratory to the Clinic (1994) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Charles E. Samuel?
Charles E. Samuel is affiliated with the following schools:
