Charles H. Williams

Charles H. Williams's AcademicInfluence.com Rankings

Charles H. Williams

Chemistry

#2635

World Rank

#3568

Historical Rank

Analytical Chemistry

#78

World Rank

#84

Historical Rank

chemistry Degrees

Download Badge

Chemistry

Charles H. Williams's Degrees

Bachelors Chemistry University of California, Berkeley
PhD Analytical Chemistry Stanford University

Why Is Charles H. Williams Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Charles H. Williams's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The determination of chromic oxide in faeces samples by atomic absorption spectrophotometry (1962) (1832)
Microsomal triphosphopyridine nucleotide-cytochrome c reductase of liver. (1962) (823)
On the reaction mechanism of yeast glutathione reductase. (1965) (386)
Thioredoxin reductase two modes of catalysis have evolved. (2000) (311)
Dietary supplement of neosugar alters the fecal flora and decreases activities of some reductive enzymes in human subjects. (1996) (299)
THE ACCUMULATION IN SOIL OF CADMIUM RESIDUES FROM PHOSPHATE FERTILIZERS AND THEIR EFFECT ON THE CADMIUM CONTENT OF PLANTS (1976) (249)
Twists in catalysis: alternating conformations of Escherichia coli thioredoxin reductase. (2000) (232)
The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli. (1997) (203)
Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis. (1994) (199)
STUDIES ON THE MECHANISM OF MICROSOMAL TRIPHOSPHOPYRIDINE NUCLEOTIDE-CYTOCHROME C REDUCTASE. (1965) (159)
Lipoamide dehydrogenase, glutathione reductase, thioredoxin reductase, and thioredoxin. (1967) (139)
Soil organic matter fractions as sources of plant-available sulphur (1975) (123)
High-performance liquid-chromatographic separation and fluorescence measurement of biogenic amines in plasma, urine, and tissue. (1978) (119)
Peptidases, Peptides, and the Mammalian Blood–Brain Barrier (1993) (111)
Acyl-coenzyme A dehydrogenase from pig kidney. Purification and properties. (1979) (108)
Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450LM. (1979) (98)
Use of a site-directed triple mutant to trap intermediates: demonstration that the flavin C(4a)-thiol adduct and reduced flavin are kinetically competent intermediates in mercuric ion reductase. (1990) (95)
Measurement of the oxidation-reduction potentials for two-electron and four-electron reduction of lipoamide dehydrogenase from pig heart. (1976) (86)
Evidence for the participation of Cys558 and Cys559 at the active site of mercuric reductase. (1989) (81)
A stable mixed disulfide between thioredoxin reductase and its substrate, thioredoxin: preparation and characterization. (1996) (78)
THE DETERMINATION OF CARBON BONDED SULFUR IN SOIL (1970) (76)
D-aspartate oxidase from beef kidney. Purification and properties. (1987) (75)
Organic sulphur fractions labelled by addition of 35S-sulphate to soil (1971) (74)
Glutathione reductase from yeast. Differential reactivity of the nascent thiols in two-electron reduced enzyme and properties of a monoalkylated derivative. (1981) (72)
Methodology employed for anaerobic spectrophotometric titrations and for computer-assisted data analysis. (1979) (72)
Teratogenic studies with 2,4,5-T and 2,4-D in the hamster (1971) (71)
The determination of phosphorus in Kjeldahl digests of plant material by automatic analysis (1971) (70)
The primary structure of D-amino acid oxidase from pig kidney. II. Isolation and sequence of overlap peptides and the complete sequence. (1982) (70)
Improved purification, amino acid analysis and molecular weight of homogenous D-amino acid oxidase from pig kidney. (1973) (68)
A method for titrating oxygen-sensitive organic redox systems with reducing agents in solution. (1969) (65)
Characterization of two active site mutations of thioredoxin reductase from Escherichia coli. (1989) (64)
Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. (2006) (63)
Extraction, chemical nature, and properties of soil organic sulphur (1969) (61)
An anaerobic titration assembly for spectrophotometric use. (1969) (60)
CARBON, NITROGEN, SULPHUR, AND PHOSPHORUS IN SOME SCOTTISH SOILS (1960) (59)
Role of active site tyrosine residues in catalysis by human glutathione reductase. (1998) (58)
Reductive and oxidative half-reactions of glutathione reductase from Escherichia coli. (1994) (57)
Reductive half-reaction of thioredoxin reductase from Escherichia coli. (1997) (54)
Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol. (1999) (53)
Differential reactivity of the two active site cysteine residues generated on reduction of pig heart lipoamide dehydrogenase. (1976) (53)
Monoamine oxidase. I. Specificity of some substrates and inhibitors. (1974) (52)
Spectral evidence for a flavin adduct in a monoalkylated derivative of pig heart lipoamide dehydrogenase. (1976) (49)
Amino acid sequence homology between pig heart lipoamide dehydrogenase and human erythrocyte glutathione reductase. (1982) (49)
Proton stoichiometry in the reduction of the FAD and disulfide of Escherichia coli thioredoxin reductase. Evidence for a base at the active site. (1983) (49)
L-lactate 2-monooxygenase from Mycobacterium smegmatis. Cloning, nucleotide sequence, and primary structure homology within an enzyme family. (1990) (48)
High-performance liquid chromatographic analysis of biogenic amines in biological materials as o-phthalaldehyde derivatives. (1979) (48)
Dietary shifts affect the gastrointestinal microflora of the giant panda (Ailuropoda melanoleuca). (2013) (46)
The presence of S degrees-containing impurities in commercial samples of oxidized glutathione and their catalytic effect on the reduction of cytochrome c. (1971) (45)
Mechanism of reduction of quinones by Trypanosoma congolense trypanothione reductase. (1994) (42)
The primary structure of D-amino acid oxidase from pig kidney. I. Isolation and sequence of the tryptic peptides. (1982) (42)
Redox potentials for yeast, Escherichia coli and human glutathione reductase relative to the NAD+/NADH redox couple: enzyme forms active in catalysis. (1998) (41)
Ion pair formation in pig heart lipoamide dehydrogenase: rationalization of pH profiles for reactivity of oxidized enzyme with dihydrolipoamide and 2-electron-reduced enzyme with lipoamide and iodoacetamide. (1977) (40)
Two-electron reduced mercuric reductase binds Hg(II) to the active site dithiol but does not catalyze Hg(II) reduction. (1986) (40)
Evidence for multiple electronic forms of two-electron-reduced lipoamide dehydrogenase from Escherichia coli. (1979) (37)
Lipoamide dehydrogenase from pig heart. Pyridine nucleotide induced changes in monoalkylated two-electron reduced enzyme. (1981) (36)
Conformational basis of energy transduction in membrane systems VIII. Configurational changes of mitochondria (1970) (36)
Reaction of both active site thiols of reduced thioredoxin reductase with N-ethylmaleimide. (1985) (35)
Some factors affecting the mineralization of organic sulphur in soils (1967) (35)
The use of lanthanum chloride to prevent interferences in the flame photometric determination of exchangeable calcium in soils (1960) (35)
Mixed disulfide with glutathione as an intermediate in the reaction catalyzed by glutathione reductase from yeast and as a major form of the enzyme in the cell. (2000) (34)
Communication between the active sites in dimeric mercuric ion reductase: an alternating sites hypothesis for catalysis. (1991) (34)
Lipoamide dehydrogenase from Escherichia coli. Steady-state kinetics of the physiological reaction. (1989) (33)
NADH inhibition and NAD activation of Escherichia coli lipoamide dehydrogenase catalyzing the NADH-lipoamide reaction. (1981) (32)
Characterization of the active center of thioredoxin reductase. (1967) (31)
A microsomal TPNH-neotetrazolium diaphorase. (1959) (31)
The effect of stage of growth on the copper, zinc, manganese, and molybdenum contents of Algerian oats grown of thirteen soils (1952) (31)
The isolation and primary structure of a paptide containing the oxidation-reduction active cystine of Escherichia coli lipoamide dehydrogenase. (1972) (31)
Beta-glucuronidase activity in the serum and liver of rats administered pesticides and hepatotoxic agents. (1969) (30)
Lactate monooxygenase. II. Site-directed mutagenesis of the postulated active site base histidine 290. (1994) (30)
Thioredoxin-thioredoxin reductase--a system that has come of age. (2000) (30)
Pre-column derivatization and high-performance liquid chromatography of biogenic amines in blood of normal and malignant hyperthermic pigs. (1982) (29)
Enzyme-monitored turnover of Escherichia coli thioredoxin reductase: insights for catalysis. (1996) (29)
Isolation, characterization and partial sequencing of cystine and thiol peptides of pig heart lipoamide dehydrogenase. (1974) (28)
The evaluation of plant-available sulphur in soils. II (1964) (28)
The sequence of amino acid residues around the oxidation-reduction active disulfide in yeast glutathione reductase. (1975) (27)
The isolation and primary structure of a peptide containing the oxidation-reduction active cystine of Escherichia coli thioredoxin reductase. (1972) (27)
Reactions of pig heart lipoamide dehydrogenase with pyridine nucleotides. Evidence for an effector role for bound oxidized pyridine nucleotide. (1979) (25)
Influence of photoirradiation on the oxidation-reduction state of thioredoxin reductase. (1968) (25)
The behaviour of leucine aminopeptidase towards thionopeptides. (1987) (25)
Lactate monooxygenase. I. Expression of the mycobacterial gene in Escherichia coli and site-directed mutagenesis of lysine 266. (1994) (24)
Direct expression of active spinach glycolate oxidase in Escherichia coli. (1992) (24)
Effect of pyridine nucleotide on the oxidative half-reaction of Escherichia coli thioredoxin reductase. (1995) (24)
The kinetic mechanism of beef kidney D-aspartate oxidase. (1988) (24)
Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme. (1993) (23)
Gas chromatographic headspace analysis of sevoflurane in blood. (1992) (23)
The evaluation of plant-available sulphur in soils (1962) (23)
Effect of pesticide administration upon esterase activities in serum and tissues of rats fed variable casein diets. (1969) (23)
Potential active-site base of thioredoxin reductase from Escherichia coli: examination of histidine245 and aspartate139 by site-directed mutagenesis. (1994) (23)
Biogeochemical interactions of carbon, nitrogen, sulfur and phosphorus in Australian agroecosystems. (1982) (23)
Lactate monooxygenase. III. Additive contributions of active site residues to catalytic efficiency and stabilization of an anionic transition state. (1994) (22)
Titration studies on the active sites of pig heart lipoamide dehydrogenase and yeast glutathione reductase as monitored by the charge transfer absorbance. (1989) (22)
Monoamine oxidase-III. Further studies of inhibition by propargylamines. (1975) (22)
Characterization of lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S. (1995) (21)
Reconstitution of Escherichia coli thioredoxin reductase with 1-deazaFAD. Evidence for 1-deazaFAD C-4a adduct formation linked to the ionization of an active site base. (1984) (21)
Chemical modification of D-amino acid oxidase. Amino acid sequence of the tryptic peptides containing tyrosine and lysine residues modified by fluorodinitrobenzene. (1982) (21)
Demonstration that bovine erythrocyte cytochrome b5 is the hydrophilic segment of liver microsomal cytochrome b5. (1982) (21)
Properties of lipoamide dehydrogenase altered by site-directed mutagenesis at a key residue (I184Y) in the pyridine nucleotide binding domain. (1991) (20)
The Gastrointestinal Bacteria of Mink (Mustela vison L): Influence of Age and Diet (1998) (20)
Studies of the ferredoxin from Thermus thermophilus. (1983) (20)
Microsomal TPNH-cytochrome c reductase. (1965) (20)
Chemical modifications of D-amino acid oxidase. Evidence for active site histidine, tyrosine, and arginine residues. (1980) (19)
Overexpression and mutagenesis of the lipoamide dehydrogenase of Escherichia coli. (1988) (19)
Lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S. Redox properties of the FAD and interactions with pyridine nucleotides. (1995) (18)
Selective inhibitors of monoamine oxidases A and B. (1984) (17)
The effect of 28-day pesticide feeding on serum and tissue enzyme activities of rats fed diets of varying casein content. (1971) (17)
Nutrient retention and processing in New Zealand streams: the influence of riparian vegetation (1986) (16)
Monoamine oxidase. II. Time-dependent inhibition by propargylamines. (1974) (16)
The isolation and characterization of the lamellar body of bovine lung. (1971) (16)
Inactivation-reactivation of two-electron reduced Escherichia coli glutathione reductase involving a dimer-monomer equilibrium. (1989) (15)
Identification of methionine-110 as the residue covalently modified in the electrophilic inactivation of D-amino-acid oxidase by O-(2,4-dinitrophenyl) hydroxylamine. (1987) (14)
Oxidation-reduction properties of Escherichia coli thioredoxin reductase altered at each active site cysteine residue. (1992) (14)
Modulation of the oxidation-reduction potential of the flavin in lipoamide dehydrogenase from Escherichia coli by alteration of a nearby charged residue, K53R. (1994) (14)
The determination of cadmium in soils, plants and fertilizers by dithizone extraction and atomic absorption spectroscopy (1972) (14)
Identification of the thiol residues involved in modifications of pig heart lipoamide dehydrogenase by cupric ion and by iodoacetamide. (1974) (14)
Amyloidosis in Alzheimer's disease. (1994) (14)
Methylation of the active center histidine 217 in D-amino acid oxidase by methyl-p-nitrobenzenesulfonate. (1984) (13)
Evaluation of Christmas Island C-grade phosphate as a fertilizer on some soils in southern New South Wales. (1970) (13)
Modification of pig heart lipoamide dehydrogenase by cupric ions. (1975) (13)
Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay. (1990) (13)
Identification of the histidine residue in D-amino acid oxidase that is covalently modified during inactivation by 5-dimethylaminonaphthalene-1-sulfonyl chloride. (1983) (12)
Evidence for direct interaction between cysteine 138 and the flavin in thioredoxin reductase. A study using flavin analogs. (1990) (12)
A comparison of two methods for the measurement of erythrocyte cholinesterase inhibition after carbamate administration to rats. (1969) (12)
A colorimetric method for the determination of molybdenum in soils (1955) (12)
The rapid determination of trace elements in soils and plants by x-ray fluorescence analysis. (1976) (12)
On the stereospecificity of monoamine oxidase (1982) (12)
Thioredoxin reductase-thioredoxin fusion enzyme from Mycobacterium leprae: comparison with the separately expressed thioredoxin reductase. (1998) (11)
Electrophilic amination of a single methionine residue located at the active site of D-amino acid oxidase by O-(2,4-dinitrophenyl)hydroxylamine. (1986) (11)
An improved spectrophotometric assay for leucine aminopeptidase. (1987) (11)
Evaluation of some fluorogenic substrates for continuous assay of aminopeptidase P. (1997) (10)
The detection of cholinesterase inhibition in erythrocytes of rats fed low levels of the carbamate Banol. (1967) (10)
REACTION OF ORGANIC SULFUR COMPOUNDS IN SOIL WITH TIN AND HYDROCHLORIC ACID (1971) (10)
Immunochemical characterisation of tachykinin immunoreactivity in the central nervous system of the snail, Helix aspersa (1991) (9)
A new specific inhibitor of monoamine oxidase A. (1982) (9)
A continuous fluorometric assay for leukotriene D4 hydrolase. (1999) (9)
Oxidation of 3-amino-1-phenylprop-1-enes by monoamine oxidase and their use in a continuous assay of the enzyme. (1988) (8)
Some aspects of mitochondrial structure (1971) (8)
An examination of Jeffries's magnesium ribbon – potassium oxalate method for the removal of free iron oxide in soils (1950) (8)
A new perspective on pyridoxal chemistry and its relevance to enzyme inhibition. (1986) (8)
Microestimation of tryptophan in plasma by a fluorometric procedure (1972) (8)
Beta-glucuronidase activity in the serum and liver of rats treated with parathion. (1970) (8)
Sequence around the Active Center Cystine of Lipoamide Dehydrogenase from Pig Heart, Comparison with the E. coli Enzyme (1972) (7)
Mechanism-based inhibition of monoamine oxidase by 3-aryl-Delta3-pyrrolines. (1998) (7)
Development of a continuous, fluorometric coupled enzyme assay for thyrotropin-releasing hormone-degrading ectoenzyme. (1999) (7)
Studies on lipoyl dehydrogenase from Escherichia coli. (1965) (7)
Effects of low concentrations of guanidine hydrochloride on pig heart lipoamide dehydrogenase. (1974) (7)
Inhibition and inactivation of monoamine oxidase by 3-amino-1-phenyl-prop-1-enes. (1992) (6)
Synthesis of ketomethylene amino pseudopeptide analogues via reductive amination of glyoxals derived from alpha-amino acids. (2000) (6)
The effect of pesticide administration on serum and tissue esterases of rats fed diets of varying casein, calcium, and magnesium content. (1969) (6)
Gly-(CSNH)-Phe resists hydrolysis by membrane dipeptidase. (1998) (6)
Nutrient removal by streambank vegetation (1984) (5)
Interactions of guanidinium chloride and pyridine nucleotides with oxidized and two-electron-reduced lipoamide dehydrogenase from Escherichia coli. (1979) (5)
L-lactate-2-monooxygenase. Sequence of peptides containing residues modified by 1-fluoro-2,4-dinitrobenzene. (1987) (5)
An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells. (1994) (4)
Zebrafish as a platform for in vivo drug discovery (2012) (4)
Purification and immunochemical studies of dipeptidyl peptidase IV from bovine kidney. (1992) (4)
Investigation on the use of a chelating resin for the extraction of sulphur from soil (1969) (4)
Mutagenic, teratogenic, and carcinogenic 6022 properties of pesticides. (1972) (4)
Pasture nitrogen in Australia. (1970) (4)
The build-up of available potassium under subterranean clover pastures on a podzolic soil (1960) (3)
400. Electrophilic substitution in benzothiazole. Part II. The bromination of the aminobenzothiazoles (1965) (3)
578. Organic complex-forming agents for metals. Part II. Preparation of 5-hydroxy- and 5 : 8-dihydroxy-quinoxalines and related compounds (1956) (3)
Biochemical and behavioural studies of monoamine oxidase inhibition (1978) (3)
The action of organo-lithium compounds on quinoxaline. Molecular compound formation involving the quinoxaline ring system (1954) (3)
The effects of several aminopeptidases towards thionopeptides. (1994) (3)
115. Organic complex-forming agents for metals. Part I. Preparation of 4-hydroxy- and 4 : 7-dihydroxy-benziminazoles and related compounds (1956) (3)
Bioassay of dieldrin for possible carcinogenicity. (1978) (3)
Endopeptidase 24:11 activity in cerebral microvessels. (1990) (3)
A tritiated photolabel specific for the active site of monoamine oxidase (1990) (2)
Synthesis of 14C-labeled inhibitors of monoamine oxidase (1981) (2)
A new route to N-substituted o-phenylenediamines (1955) (2)
Aminopeptidase activities present in tissues of Helix aspersa. (1991) (2)
Aggregation of Alzheimer's peptides. (1994) (2)
'Crystal-like structures' of boiled beef heart mitochondria. (1972) (2)
Graphical analysis of interactions between oxidation-reduction sites in two site oxidation-reduction proteins. (1984) (1)
STUDIES ON THE ASSOCIATION OF P-450 LM2 WITH NADPH-CYTOCHROME P-450 REDUCTASE AND WITH TRYPTIC PEPTIDES DERIVED FROM THE REDUCTASE (1980) (1)
Aspects of tyrosine metabolism in schizophrenia (1971) (1)
beta-Glucuronidase activity in the urine, serum, kidney and bladder of rats fed 2-chloro-4-nitrobenzamide, 3,5-dinitrobenzamide or 3,5-dinitro-o-toluamide. (1969) (1)
The behaviour of aryl pyrrolines with monoamine oxidase. (1999) (1)
Proton nuclear magnetic resonance investigation of the mechanism of flavin C-4a adduct formation induced by oxidized nicotinamide adenine dinucleotide binding to monoalkylated pig heart lipoamide dehydrogenase. (1983) (1)
The oxidative and reductive half reactions of subunit interface mutants of Escherichia coli glutathione reductase. (1996) (1)
Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of full length amyloid peptides (1994) (0)
Amine oxidases of cerebral microvessels (1992) (0)
Aminopeptidase activities in Helix aspersa. (1991) (0)
N-(4-azido benzoyl)FnLRFamide, a putative photoaffinity label for the FMRFamide receptor. (1994) (0)
beta-phenylethanolamine as a substrate for monoamine oxidase [proceedings]. (1977) (0)
Assay of neuropeptidases using fluorogenic substrates. (1997) (0)
The suppression of calcium interference in the flame photometric determination of exchangeable sodium in soils (1960) (0)
A new time-dependent reversible inhibitor of monoamine oxidase. (1996) (0)
Modern Problems of Pharmacopsychiatry. Vol. 19. Monoamine Oxidase and its Selective Inhibitors. Edited by Helmut Beckmann and Peter Riederer. Basel: S. Karger. 1983. Pp 350. SFr. 198, $118.75. (1984) (0)
An Anaerobic Titration Assembly for Spectrophotometric Use 1 (2003) (0)
Further studies on the action of aminopeptidases towards sulphur-containing substrates. (1995) (0)
Solid phase synthesis of N-carboxy alkyl-containing peptides derived from enantiopure alpha-keto-beta-aminoacids. (1998) (0)
Conformational studies on heptapeptide analogues of the invertebrate neuropeptide FMRFamide. (1993) (0)
Effects of the mutations Glu22 to Gln and Ala21 to Gly on zinc binding to the Aβ peptide (1994) (0)
Mechanism of cerebral amyloidogenesis in Alzheimer's disease (1994) (0)
Binding of some FMRFamide analogues to membranes from brain of Helix aspersa (1992) (0)
Conformational dynamics of E. coli thioredoxin reductase: identification of two catalytically important states by ultra-fast flavin fluorescence spectroscopy (2001) (0)
Brain Biochemistry and Brain Disorders. By Philip G. Strange. Oxford: Oxford University Press. 1992. 342 pp. £19.50. (1993) (0)
Some properties of high and low molecular weight aminopeptidase activities in tissues of helix aspersa (1990) (0)
Microestimation of tryptophan in palsma by a flourometric procedure. (1972) (0)
Purification and immunological studies on the peripheral type benzodiazepine acceptor. (1991) (0)
Mechanism-based proteinase inhibitors : a critical review (2009) (0)
13C-labelling of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (1989) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Charles H. Williams?

Charles H. Williams is affiliated with the following schools:

Queen's University Belfast
University of Michigan
Heidelberg University