Cameron J. Koch
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Biology
Cameron J. Koch's Degrees
- PhD Biomedical Sciences University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Cameron J. Koch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours (1996) (2431)
- Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998) (2183)
- Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998) (1998) (579)
- Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. (1997) (409)
- Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension (2006) (390)
- Candidate genes for the hypoxic tumor phenotype. (2000) (344)
- Hypoxia Is Important in the Biology and Aggression of Human Glial Brain Tumors (2004) (320)
- Prognostic significance of tumor oxygenation in humans. (2003) (255)
- Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. (1993) (250)
- Adaptation of chondrocytes to low oxygen tension: Relationship between hypoxia and cellular metabolism (1996) (223)
- Detection of hypoxia in human squamous cell carcinoma by EF5 binding. (2000) (217)
- Comparative Measurements of Hypoxia in Human Brain Tumors Using Needle Electrodes and EF5 Binding (2004) (212)
- Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity. (1995) (203)
- Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. (2002) (202)
- Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response (2008) (163)
- Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia. (1986) (162)
- Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. (1987) (156)
- Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy. (2006) (150)
- Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. (1995) (149)
- Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve. (1997) (148)
- Mechanism of copper-catalyzed oxidation of glutathione. (1998) (148)
- [18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure. (2001) (147)
- The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide. (1997) (141)
- Tumor vascular changes mediated by inhibition of oncogenic signaling. (2009) (139)
- Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5 (2003) (139)
- Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin. (1993) (138)
- Permanent Anatomic Closure of the Ductus Arteriosus in Newborn Baboons: The Roles of Postnatal Constriction, Hypoxia, and Gestation (1999) (134)
- Hypoxic Heterogeneity in Human Tumors: EF5 Binding, Vasculature, Necrosis, and Proliferation (2001) (130)
- Depletion of tumor oxygenation during photodynamic therapy: detection by the hypoxia marker EF3 [2-(2-nitroimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl)acetamide ]. (2000) (127)
- Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. (1995) (124)
- Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy (2009) (123)
- Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules. (1990) (116)
- Oxygen levels in normal and previously irradiated human skin as assessed by EF5 binding. (2006) (113)
- 2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors. (1996) (105)
- A thin-film culturing technique allowing rapid gas-liquid equilibration (6 sec) with no toxicity to mammalian cells. (1984) (102)
- Extravascular diffusion of tirapazamine: effect of metabolic consumption assessed using the multicellular layer model. (1998) (101)
- Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease. (1999) (99)
- Mechanism of copper-catalyzed autoxidation of cysteine. (1999) (97)
- Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles. (2003) (97)
- Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1. (2000) (96)
- p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment (2004) (96)
- Photodynamic therapy creates fluence rate-dependent gradients in the intratumoral spatial distribution of oxygen. (2002) (94)
- correction: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998) (94)
- Toxicity, radiation sensitivity modification, and metabolic effects of dehydroascorbate and ascorbate in mammalian cells , (1978) (90)
- The effect on the Km for radiosensitization at 0 degree C of thiol depletion by diethylmaleate pretreatment: quantitative differences found using the radiation sensitizing agent misonidazole or oxygen. (1984) (88)
- Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. (1995) (88)
- Combined Prostaglandin and Nitric Oxide Inhibition Produces Anatomic Remodeling and Closure of the Ductus Arteriosus in the Premature Newborn Baboon (2001) (84)
- Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells. (2004) (84)
- Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements (1999) (83)
- Interlaboratory variation in oxygen tension measurement by Eppendorf “Histograph” and comparison with hypoxic marker (1997) (82)
- The effect of extreme hypoxia on the repair of DNA single-strand breaks in mammalian cells. (1975) (81)
- Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12. (1999) (80)
- The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras. (2001) (76)
- Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors. (1996) (75)
- Oxygen dependence of binding of misonidazole to rodent and human tumors in vitro. (1987) (74)
- Metabolism induced binding of 14C-misonidazole to hypoxic cells: kinetic dependence on oxygen concentration and misonidazole concentration. (1984) (74)
- Detection of Reactive Oxygen Species via Endogenous Oxidative Pentose Phosphate Cycle Activity in Response to Oxygen Concentration (2007) (74)
- Plateau phase in growth induced by hypoxia. (1973) (73)
- Binding of misonidazole to hypoxic cells in monolayer and spheroid culture: evidence that a side-chain label is bound as efficiently as a ring label. (1985) (73)
- Variation in radiation response of mammalian cells as a function of oxygen tension. (1973) (72)
- Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles (2001) (72)
- Ascorbate anion potentiates cytotoxicity of nitro-aromatic compounds under hypoxic and anoxic conditions. (1979) (71)
- A novel technique for measuring human tissue pO2 at the cellular level. (1986) (69)
- Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts (1996) (67)
- Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and γ radiation (2005) (67)
- Factors that increase the contractile tone of the ductus arteriosus also regulate its anatomic remodeling. (2001) (65)
- Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. (1987) (65)
- VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus. (2002) (64)
- Hypoxia and VEGF mRNA expression in human tumors. (2001) (63)
- A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status (2008) (62)
- Mechanism of production of hydroxyl radicals in the copper-catalyzed oxidation of dithiothreitol. (1997) (61)
- Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: comparative measurements using EF5 binding and the Eppendorf needle electrode. (2000) (60)
- Vasa Vasorum Hypoperfusion Is Responsible for Medial Hypoxia and Anatomic Remodeling in the Newborn Lamb Ductus Arteriosus (2002) (60)
- Overview of radiosensitivity of human tumor cells to low-dose-rate irradiation. (2008) (60)
- Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1. (1999) (60)
- The effect of hypoxia on the generation time of mammalian cells. (1973) (59)
- Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome. (2007) (59)
- Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis (1977) (59)
- EF5 binding and clinical outcome in human soft tissue sarcomas. (2006) (58)
- Hypoxia and Photofrin Uptake in the Intraperitoneal Carcinomatosis and Sarcomatosis of Photodynamic Therapy Patients (2004) (58)
- Combined radiation-protective and radiation-sensitizing agents: II. Radiosensitivity of hypoxic or aerobic Chinese hamster fibroblasts in the presence of cysteamine and misonidazole: implications for the "oxygen effect" (with appendix on calculation of dose-modifying factors). (1981) (57)
- In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. (2011) (55)
- Mutation in the Glucose-6-phosphate Dehydrogenase Gene Leads to Inactivation of Ku DNA End Binding during Oxidative Stress* (2002) (54)
- p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia. (2005) (54)
- Biodistribution and dosimetry of 18F-EF5 in cancer patients with preliminary comparison of 18F-EF5 uptake versus EF5 binding in human glioblastoma (2010) (53)
- Imaging and Analytical Methods as Applied to the Evaluation of Vasculature and Hypoxia in Human Brain Tumors (2008) (53)
- The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. (2010) (51)
- Is misonidazole binding to mouse tissues a measure of cellular pO2? (1987) (51)
- Interleukin 2 expression by tumor cells alters both the immune response and the tumor microenvironment. (1998) (50)
- The effect of extreme hypoxia and glucose on the repair of potentially lethal and sublethal radiation damage by mammalian cells. (1977) (50)
- The effect of extreme hypoxia on recovery after radiation by synchronized mammalian cells. (1971) (48)
- Hypoxia in human intraperitoneal and extremity sarcomas. (2001) (46)
- Radiation-induced DNA damage in tumors and normal tissues. III. Oxygen dependence of the formation of strand breaks and DNA-protein crosslinks. (1995) (46)
- Alteration of tumour response to radiation by interleukin-2 gene transfer (2000) (46)
- In situ oxygen utilization in the rat intervertebral disc (2007) (45)
- Tumor hypoxia as a modifier of DNA strand break and cross-link repair. (2009) (44)
- THE OXIDATION OF ASCORBATE BY ELECTRON AFFINIC DRUGS AND CARCINOGENS (1978) (43)
- Early detection of radiation therapy response in non‐Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging (2010) (43)
- Binding of misonidazole to V79 spheroids and fragments of Dunning rat prostatic and human colon carcinomas in vitro: diffusion of oxygen and reactive metabolites. (1984) (42)
- Chondrocytes in the endochondral growth cartilage are not hypoxic. (1997) (40)
- In vivo colocalization of 2-nitroimidazole EF5 fluorescence intensity and electron paramagnetic resonance oximetry in mouse tumors. (2003) (40)
- The radiation response of hypoxic cells in EMT6 spheroids in suspension culture does model data from EMT6 tumors. (1983) (39)
- Optimizing hypoxia detection and treatment strategies. (2015) (39)
- Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies. (1996) (38)
- Importance of Antibody Concentration in the Assessment of Cellular Hypoxia by Flow Cytometry: EF51 and Pimonidazole (2008) (37)
- Binding of misonidazole to EMt6 and V79 spheroids. (1982) (37)
- Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients (2014) (37)
- Radiation Response of Cells during Altered Protein Thiol Redox (2003) (37)
- Effect of sub-optimal temperatures on survival of mammalian cells. (1971) (36)
- Studies of type IV collagenase regulation by hypoxia. (1998) (36)
- Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. (2004) (36)
- Synthesis of new hypoxia markers EF1 and [18F]-EF1. (1999) (36)
- Retinoic acid modulation of glutathione and cysteine metabolism in chondrocytes. (1996) (35)
- Evaluation of the concept of "hypoxic fraction" as a descriptor of tumor oxygenation status. (1997) (35)
- Initial evidence that blood-borne microvesicles are biomarkers for recurrence and survival in newly diagnosed glioblastoma patients (2016) (34)
- Radioprotection of DNA in isolated nuclei by naturally occurring thiols at intermediate oxygen tension. (1992) (34)
- Tissue hypoxia inhibits prostaglandin and nitric oxide production and prevents ductus arteriosus reopening. (2000) (34)
- The Km for Radiosensitization of Human Tumor Cells by Oxygen is Much Greater than 3 mmHg and is Further Increased by Elevated Levels of Cysteine (2001) (33)
- Tamoxifen induces hypoxia in MCF-7 xenografts. (1997) (33)
- Human tumor cells segregate into radiosensitivity groups that associate with ATM and TP53 status (2007) (32)
- The oxygen-enhancement ratio for reproductive death induced by 3H or 125I damage in mammalian cells. (1975) (32)
- Response of V79 cells to low doses of X-rays and negative pi-mesons: clonogenic survival and DNA strand breaks. (1996) (30)
- G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide. (2000) (30)
- The catalytic effect of the carcinogen "4-nitroquinoline-N-oxide" on the oxidation of vitamin C. (1976) (30)
- Low pO2 and β-Estradiol Induce VEGF in MCF-7 and MCF-7-5C Cells: Relationship to in vivo Hypoxia (2001) (29)
- Radiosensitization of hypoxic mammalian cells by diamide. I. Effects of experimental conditions on survival. (1975) (28)
- Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system. (1986) (28)
- Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. (2002) (28)
- Mechanisms of blood flow and hypoxia production in rat 9L-epigastric tumors. (2012) (27)
- The Reduction Activation of Nitroimidazoles; Modification by Oxygen and other Redox-Active Molecules in Cellular Systems (1990) (27)
- Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA (2015) (27)
- Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-L-cysteine or L-buthionine-S,R-sulfoximine. (1998) (27)
- Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia–ischemia (1999) (27)
- Single‐cell measurement of the uptake, intratumoral distribution and cell cycle effects of cisplatin using mass cytometry (2015) (27)
- Genotype-dependent radiosensitivity: Clonogenic survival, apoptosis and cell-cycle redistribution (2008) (26)
- Non‐invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F‐EF5 and positron emission tomography (2007) (26)
- Oxygen effects in radiobiology. (1982) (25)
- The Effect of Oxygen on the Repair of Radiation Damage by Cells and Tissues1 (1979) (25)
- Effects of ultra-high dose rate FLASH irradiation on the tumor microenvironment in Lewis lung carcinoma: role of myosin light chain. (2020) (25)
- The alkaline elution technique for measuring DNA single strand breaks: increased reliability and sensitivity. (1994) (24)
- The radiation response of cells from 9L gliosarcoma tumours is correlated with [F18]-EF5 uptake (2009) (23)
- Imaging hypoxia and blood flow in normal tissues. (1997) (23)
- Respiration of mammalian cells at low concentrations of oxygen: I. Effect of hypoxic-cell radiosensitizing drugs. (1978) (23)
- Hypoxia in the Androgen-Dependent Shionogi Model for Prostate Cancer at Three Stages1 (2004) (23)
- Measurements of very low oxygen tensions in unstirred liquids (1972) (22)
- A model of wound healing in chronically radiation-damaged rat skin. (1998) (22)
- Combined radiation-protective and radiation-sensitizing agents. III: Radiosensitization by misonidazole as a function of concentrations of endogenous glutathione or exogenous thiols. (1986) (22)
- Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: Mechanism and implication (2008) (21)
- The disaggregation, separation and identification of cells from irradiated and unirradiated EMT6 mouse tumors. (1980) (20)
- Role of scavenger-derived radicals in the induction of double-strand and single-strand breaks in irradiated DNA. (1995) (20)
- Quantitation of hypoxia in multicellular spheroids by video image analysis. (1989) (20)
- Intratumoral Hypoxia Reduces IFN-γ–Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model (2019) (20)
- Factors influencing the oxygen consumption and radiation response of cultured mammalian cells. (1983) (19)
- Radiosensitization of hypoxic mammalian cells by diamide. II. Studies of mechanism. (1977) (19)
- Oxygen supply to spheroids in spinner and liquid-overlay culture. (1984) (19)
- Distribution of misonidazole adducts in 9L gliosarcoma tumors and spheroids: implications for oxygen distribution. (1992) (19)
- Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients. (2012) (18)
- Role of Vicinal Protein Thiols in Radiation and Cytotoxic Responses (2006) (18)
- Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles. Implications for use as hypoxic cell markers. (1993) (18)
- PARP-1 Expression Quantified by [18F]FluorThanatrace: A Biomarker of Response to PARP Inhibition Adjuvant to Radiation Therapy. (2017) (17)
- Combined radiation-protective and radiation-sensitizing agents. IV: Measurement of intracellular protector concentrations. (1989) (17)
- Comparisons of cellular radiation response using absolute rather than relative parameters. (1992) (17)
- Effect of oxygen on radiation-induced DNA damage in isolated nuclei. (1999) (17)
- Oxidation of cellular thiols by hydroxyethyldisulphide inhibits DNA double-strand-break rejoining in G6PD deficient mammalian cells. (2000) (17)
- Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis. (2007) (16)
- Monoclonal antibodies differentially reactive with native and reductively modified Bowman-Birk protease inhibitor. (1995) (16)
- DNA strand breakage by bivalent metal ions and ionizing radiation (2007) (16)
- Imaging hypoxia in diseased tissues. (1997) (15)
- Oxygen dependence of product formation in irradiated adenosine 5'-monophosphate. (1988) (15)
- Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air. (1994) (15)
- Enhanced radiation-sensitivity by preincubation with nitroimidazoles: effect of glutathione depletion. (1994) (15)
- Modification of radiation-induced strand breaks by glutathione: comparison of single- and double-strand breaks in SV40 DNA. (1995) (15)
- Radiolytic reduction of protein and nonprotein disulfides in the presence of formate: a chain reaction. (1991) (15)
- Re: Differential impact of FLASH versus conventional dose rate irradiation: Spitz et al. (2019) (15)
- Molecular suicide studies of 125I and 3H disintegration in the DNA of Chinese hamster cells. (1978) (15)
- Cell survival in V79 multicell spheroids treated with dehydroascorbate, 5-thio-D-glucose and 2-deoxy-D-glucose. (1978) (14)
- Misonidazole: inter-related factors affecting cytotoxicity. (1982) (13)
- Novel Double-Hit Model of Radiation and Hyperoxia-Induced Oxidative Cell Damage Relevant to Space Travel (2016) (13)
- Metabolism and radiosensitization of 4,5-dimethylmisonidazole, a ring-substituted analog of misonidazole. (1992) (13)
- DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts. (2000) (12)
- Human Esophageal Cancer Is Distinguished from Adjacent Esophageal Tissue by Tissue Cysteine Concentrations (2002) (12)
- Synergistic chemical radiosensitization of hypoxic mammalian cells. (1976) (11)
- Radioresistance of anoxic cells and the effects of PNAP on the radiation response of an in vitro tumor model. (1973) (11)
- Analysis of tumor thiol concentrations: comparison of flow cytometric with chemical and biochemical techniques. (1997) (11)
- The release of oxygen from polystyrene Petri dishes. (1972) (10)
- The Farnesyltransferase Inhibitor L 744 , 832 Reduces Hypoxia in Tumors Expressing (2001) (10)
- pO(2)-dependent NO production determines OPPC activity in macrophages. (2010) (10)
- Catalysis of fluorine addition to double bond: an improvement of method for synthesis of (18)F PET agents. (2010) (10)
- In regard to Vordermark et al. (Int J Radiat Oncol Biol Phys 2004;58:1242-1250). (2004) (10)
- DNA damaging agents improve stable gene transfer efficiency in mammalian cells. (1998) (9)
- The boys in the island (1958) (9)
- The measurement of bioreductive capacity of tumor cells using methylene blue. (1998) (9)
- Simulation of the cellular oxygen effect with an SV40 DNA model system using DNA strand breaks as an end point. (1996) (9)
- AN EFFECTIVE SYNTHETIC ROUTE TO EF5 (1998) (9)
- Radiosensitization/radioprotection: methods of analysis. (1985) (8)
- Quantitative spatial analysis of hypoxia and vascular perfusion in tumor sections. (2003) (8)
- Enhancement of X-ray induced potentially lethal damage by low temperature storage of mammalian cells. (1977) (8)
- Recognition of platinum-induced DNA damage by nuclear proteins: screening for mechanisms. (1994) (8)
- Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia. (1998) (8)
- Effect of etanidazole on absolute sensitivity and increased radioresistance in hypoxic cells at low doses (1994) (7)
- Cyanide insensitive respiration in mammalian cells: an artifact of mycoplasmal contamination. (1983) (7)
- Tumor response to radiotherapy is dependent on genotype-associated mechanisms in vitro and in vivo (2010) (7)
- 4 – Chemical Modifiers of Radiation Response (2010) (7)
- Radiation response and other characteristics of the 9l rat glioma grown as an epigastric tissue isolate (1994) (6)
- Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts. (1998) (6)
- Pharmacokinetics and cytotoxicity of RSU-1069 in subcutaneous 9L tumours under oxic and hypoxic conditions. (1991) (6)
- Tissue oxygen sensing and the carotid body. (1998) (6)
- Effects of hyperglycemia on oxygenation, radiosensitivity and bioenergetic status of subcutaneous RIF-1 tumors. (2002) (6)
- Intracellular PO2 of the carotid body. (2000) (6)
- Buoyant density of EMT6 fibrosarcoma cells: I. Effect of hypoxic growth conditions in vitro. (1980) (5)
- Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells (2013) (5)
- Combined Prostaglandin (PG)-and-Nitric Oxide (NO) Inhibition Produces Permanent Closure of PDA in Preterm Baboons (1999) (5)
- 2070 : 18F EF5 PET Imaging With Immunohistochemical Validation in Patients With Brain Lesions (2006) (5)
- Hypoxic Heterogeneity in Human Tumors (2001) (5)
- Comment on the hypothesis that hyperthermia facilitates reoxygenation. (1995) (5)
- Sequentially-induced responses define tumour cell radiosensitivity (2011) (5)
- Buoyant density of EMT6 fibrosarcoma cells: time course of the density changes after growth in hypoxia. (1980) (4)
- A noveltechnique formeasuring humantissue pO2atthe cellular level (1986) (3)
- Non-Invasive Imaging of Hypoxia — Challenges and Opportunities (2012) (3)
- Candidate Genes for the Hypoxic Tumor Phenotype 1 (2000) (3)
- Do low doses of radiation induce a response modulating induction or repair of DNA single-strand breaks? (1994) (3)
- Preservation of functional and regulatory domains of expressed bcl-2 genes in non-Hodgkin's lymphoma. (1996) (3)
- A Two-Component Assay for Hypoxia Incorporating Long-Term Nitroreduction and Short-Term DNA-Damage Allows Differentiation of the Three Hypoxia Sub-types (2018) (3)
- Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding (2015) (3)
- Implications for Radiotherapy VEGF Expression and Increases Tumor Oxygenation : and α Nelfinavir Down-regulates Hypoxia-Inducible Factor 1 (2006) (3)
- Further investigations into the nature of the trigger of increased radioresistance: The effect of {sup 14}C and {sup 3}H thymidine on low-dose hypersensitivity (1995) (2)
- Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18 FEF 5 and positron emission tomography (2007) (2)
- Immunocytochemical labelling of aerobic and hypoxic mammalian cells using a platinated derivative of EF5. (1996) (2)
- Oxygen sensor design: analysis and correction of problems associated with zero current, stability and structure. (2003) (2)
- Targeting the PI3K/mTOR Pathway Reduces Tumor Hypoxia and Decreases Oxygen Consumption (2013) (2)
- 61 Simulation of the cellular oxygen effect with an in vitro model system using double strand DNA breaks as an endpoint (1995) (2)
- Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate (2014) (2)
- The Mechanisms of Radiation Protection by Non-Protein Sulfhydryls: Glutathione, Cysteine, and Cysteamine (2021) (2)
- Invited editorial for the paper by Silvoniemi et al. “Repeatability of tumor hypoxia imaging using [18F]EF5 PET/CT in head and neck cancer.” in this issue of EJNMMI (2018) (1)
- Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (Nature (1998) 394 (485-490)) (1998) (1)
- Impact of hypoxia on IFNγ-dependent responses: implications for radiotherapy and anti-tumor immunity (2016) (1)
- In regard to Brown et al. (Int J Radiat Oncol Biol Phys 2010;78:323-327). (2011) (1)
- 215 : Nelfinavir Downregulates HIF-1alpha and VEGF expression and Increases Tumor Oxygenation: Implications for Radiotherapy (2006) (1)
- A Pilot Study of F18 EF5 PET/CT Imaging in Patients With Carcinoma of the Cervix. (2013) (1)
- Electronic systems for a microspectrophotometer (1973) (1)
- Hypoxia initiates Ductus Arteriosus Remodeling. • 101 (1997) (1)
- Effects of hypothermia on the sodium pump, oxygen consumption, and survival in the V79 mammalian cell line☆ (1986) (1)
- Non-invasive assessment of tumor hypoxia with the 2-nitroimidazole 18F-EF1 and PET. (1999) (1)
- Letter to the Editor Re: Ogawa, Y. Cancers 2016, 8, 28 (2016) (1)
- Re: Devic et al. (Int J Radiat Oncol Biol Phys 2010;78:1555-1562). (2011) (1)
- Androgen Withdrawal Fails to Induce Detectable Tissue Hypoxia in the Prostate (2005) (0)
- Interaction of thiols and non-thiol {center_dot}OH scavengers in the modification of radiation-induced DNA damage (1995) (0)
- The radiation response of tumour cell subpopulations separated by unit gravity sedimentation. Abstr. (1978) (0)
- erratum Perinuclear localizationof chromatin facilitates transcriptional silencing (0)
- Abstract 1037: Agents that target the PI3K/mTOR pathway decrease oxygen consumption, reduce tumor hypoxia and improve radiation response in solid tumors. (2013) (0)
- Radiosensitization of anoxic cells and tumors with diamide. Abstr. (1974) (0)
- Comment on the Paper by Van Der Schans et al. (1986) (0)
- Cytotoxicity of SR-4233 in human lung carcinoma cells under both aerobic and hypoxic conditions (1993) (0)
- The Prognostic Role of Hypoxia in Head and Neck Squamous Cell Tumors, as Measured by EF5, is Influenced by EF5 Binding Patterns (2005) (0)
- Microenvironment and Immunology In Vivo Profiling of Hypoxic Gene Expression in Gliomas Using the Hypoxia Marker EF 5 and Laser-capture Microdissection (2011) (0)
- Re-oxygenation of tumors expressing activated H-ras after farnesyltransferase inhibitor L744, 832 treatment (2000) (0)
- Abstract 2272: Comparison of bioreductive metabolism of tirapazamine, its second generation analogue SN 30000 and hypoxia imaging agent EF5 in human tumor cell lines (2010) (0)
- Response to Letter of R. C. Richmond (1993) (0)
- Oxygen consumption of v79 and emt6 spheroids. Abstr. (1982) (0)
- 190 Microenvironment of brain tumors: Hypoxia, proliferation and vasculature (2006) (0)
- BI-08MICROVESICLES CAN DISTINGUISH BETWEEN TUMOR PROGRESSION AND TREATMENT EFFECT/PSEUDOPROGRESSION IN GLIOBLASTOMA PATIENTS TREATED WITH RADIATION AND TEMOZOLOMIDE. (2014) (0)
- The Role of Hypoxia in Ductus Closure and Reopening (1999) (0)
- Oxygen regulation of chondrocyte function: Reevaluation of the hypothesis that cells in the growth plate are hypoxic (1998) (0)
- Poster presentations (2007) (0)
- Abstract 2442: Detection of tissue hypoxia with EF5 (2018) (0)
- The repair of sublethal damage by emt6 cells in the exponential and plateau phases of growth. Abstr. (1977) (0)
- Abstract2628: Quantitative Image Analysis of Tumor Vasculature and Hypoxia in Human Glioblastoma Multiforme (GBM) (2006) (0)
- 2665 : Does Flow Cytometry of EF5 Binding Show a Correlation With Immunohistochemical Findings in Human Tumors? (2006) (0)
- , Sylvain Chemtob , Nahid Waleh , Cameron J . Koch production and prevents ductus arteriosus reopening Tissue hypoxia inhibits prostaglandin and nitric oxide (2000) (0)
- The preparation of compounds for the determination of hypoxia (2000) (0)
- Abstract SY34-04: Do we need to know what pO2 hypoxia is (2010) (0)
- Gefitinib (ZD1839) Decreases Vascular Endothelial Growth Factor (VEGF) Expression by Hypoxia-Inducible Factor (HIF)-1 Independent and Dependent Mechanisms and Increases Tumor Oxygenation (2005) (0)
- Effects of the EGFR Inhibitor Erlotinib on Tumor Microenvironment: Implications for Therapy (2008) (0)
- Intratumoral Hypoxia Reduces IFN- (2019) (0)
- The pO2 of Cycling Cells is an Independent Predictor of Recurrence and Survival in Human Glioblastomas (2008) (0)
- 2019 Preliminary results of a phase I trial of the 2-nitroimidazole, EF5, an agent for the detection of tumor hypxia (1999) (0)
- Detection of hypoxia with reagents containing 2-nitroimidazole compounds and methods of making such reagents (1997) (0)
- Elevated thiol levels in esophageal tumors: Cause of radiation and chemotherapy resistance? (2000) (0)
- The boys in the island / C.J. Koch (1986) (0)
- Hypoxia and cellular proliferation in human tumors (2001) (0)
- Association of in-vivo and ex-vivo measurements of tissue oxygenation and photosensitizer concentration in patients with intraperitoneal caracinomatosis (2006) (0)
- Buoyant density of EMT6 fibrosarcoma cells (1980) (0)
- Abstract 5004:In vivoprofiling of hypoxic mRNA and miRNA expression in gliomas and head and neck tumors (2011) (0)
- An Effective Synthetic Route to EF5. (1998) (0)
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What Schools Are Affiliated With Cameron J. Koch?
Cameron J. Koch is affiliated with the following schools:
