Chi-yun Kung

Q: What Schools Are Affiliated With Chi-yun Kung

Chi-yun Kung is affiliated with the following schools: University of Maryland, College Park, University of California, Santa Barbara, University of Tokyo, University of California, Los Angeles, Princeton University, Drexel University, University of Wisconsin–Madison

Chi-yun Kung's AcademicInfluence.com Rankings

Chi-yun Kung

Physics

#6176

World Rank

#8085

Historical Rank

Biophysics

#249

World Rank

#260

Historical Rank

physics Degrees

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Physics

Chi-yun Kung's Degrees

PhD Biophysics Stanford University
Masters Physics Stanford University
Bachelors Physics National Taiwan University

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Chi-yun Kung's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A large-conductance mechanosensitive channel in E. coli encoded by mscL alone (1994) (699)
Pressure-sensitive ion channel in Escherichia coli. (1987) (629)
A possible unifying principle for mechanosensation (2005) (614)
Mechanosensitive ion channels of E. coli activated by amphipaths (1990) (452)
Energetic and Spatial Parameters for Gating of the Bacterial Large Conductance Mechanosensitive Channel, MscL (1999) (384)
A mechanosensitive ion channel in the yeast plasma membrane. (1988) (381)
Calmodulin as an ion channel subunit. (2002) (341)
Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution. (1993) (317)
Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities. (1997) (311)
Mechanosensitive channels in microbes. (2010) (270)
A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca2+-permeable channel in the yeast vacuolar membrane (2001) (240)
COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae (1992) (224)
Feeling the hidden mechanical forces in lipid bilayer is an original sense (2014) (219)
Modified reconstitution method used in patch-clamp studies of Escherichia coli ion channels. (1989) (216)
Design of allele-specific inhibitors to probe protein kinase signaling (1998) (211)
Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli. (1996) (209)
One face of a transmembrane helix is crucial in mechanosensitive channel gating. (1998) (196)
Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity. (1999) (194)
Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coli. (1996) (192)
Biochemical studies of the excitable membrane of Paramecium tetraurelia. III. Proteins of cilia and ciliary membranes (1980) (183)
A mechanosensitive channel in whole cells and in membrane patches of the fungus Uromyces (1991) (180)
Genetic dissection of behavior in paramecium (1975) (163)
The transient receptor potential channel on the yeast vacuole is mechanosensitive (2003) (155)
The physiological basis of taxes in Paramecium. (1982) (146)
Generation of Monospecific Nanomolar Tyrosine Kinase Inhibitors via a Chemical Genetic Approach (1999) (143)
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements (2014) (140)
Functional and structural conservation in the mechanosensitive channel MscL implicates elements crucial for mechanosensation (1998) (138)
Ion channels in yeast. (1986) (135)
Genic mutants with altered system of excitation in Paramecium aurelia. II. Mutagenesis, screening and genetic analysis of the mutants. (1971) (134)
Mechanosensitive channels of bacteria. (1999) (133)
Yeast K1 killer toxin forms ion channels in sensitive yeast spheroplasts and in artificial liposomes. (1990) (131)
Mutations in a Bacterial Mechanosensitive Channel Change the Cellular Response to Osmotic Stress* (1997) (130)
Mutations in paramecium calmodulin indicate functional differences between the C-terminal and N-terminal lobes in vivo (1990) (129)
Wild-type and Brachyolmia-causing Mutant TRPV4 Channels Respond Directly to Stretch Force* (2010) (129)
Rotation and twist of the central-pair microtubules in the cilia of Paramecium (1980) (129)
Yeast casein kinase I homologues: an essential gene pair. (1992) (127)
Separation of membrane currents using a Paramecium mutant (1977) (121)
The pair of central tubules rotates during ciliary beat in Paramecium (1979) (121)
Behavioral genetics of Paramecium. (1987) (110)
Prokaryotic K(+) channels: from crystal structures to diversity. (2005) (107)
Ion channels in microbes. (2008) (107)
Ion channels in microbes. (1999) (99)
YKC1 encodes the depolarization‐activated K+ channel in the plasma membrane of yeast (1995) (99)
Genetic modification of electric properties in an excitable membrane (paramecium-calcium conductance-electrophysiological measurements-membrane mutant). (1972) (95)
Chemically charging the pore constriction opens the mechanosensitive channel MscL. (2001) (89)
Ultrastructure of the proximal region of somatic cilia in Paramecium tetraurelia (1978) (88)
Restoration by calmodulin of a Ca2+-dependent K+ current missing in a mutant of Paramecium. (1986) (84)
Stiffened lipid platforms at molecular force foci (2013) (81)
Mutant analysis shows that the Ca2+-induced K+ current shuts off one type of excitation in Paramecium. (1983) (77)
Structure of Paramecium tetraurelia calmodulin at 1.8 Å resolution (1993) (73)
Ion channel activities in the Escherichia coli outer membrane. (1990) (72)
Calcium-Induced Ciliary Reversal in the Extracted Models of "Pawn," a Behavioral Mutant of Paramecium (1973) (68)
Ion channel regulation by calmodulin binding (1994) (68)
An anticalmodulin drug, W-7, inhibits the voltage-dependent calcium current in Paramecium caudatum. (1984) (68)
Random mutagenesis reveals a region important for gating of the yeast K+ channel Ykc1 (1997) (66)
Ca-induced K+-outward current in Paramecium tetraurelia. (1980) (65)
Voltage-dependent calcium channels from Paramecium cilia incorporated into planar lipid bilayers. (1984) (63)
Calmodulin mutants and Ca2(+)-dependent channels in Paramecium. (1991) (62)
In vivo Paramecium mutants show that calmodulin orchestrates membrane responses to stimuli. (1992) (61)
Voltage Sensitive Ca-Channels and the Transient Inward Current in Paramecium Tetraurelia (1979) (60)
Gating the bacterial mechanosensitive channel MscL in vivo (2002) (60)
A Ca-induced Na-current in Paramecium. (1980) (58)
Calcium current activated upon hyperpolarization of Paramecium tetraurelia (1992) (56)
Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria. (1996) (55)
Gain‐of‐function mutations indicate that Escherichia coli Kch forms a functional K+ conduit in vivo (2003) (53)
Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate (2007) (52)
Membrane‐derived oligosaccharides (MDO's) promote closing of an E. coli porin channel (1992) (52)
Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations (2011) (52)
Functional Reconstitution as an Assay for Biochemical Isolation of Channel Proteins: Application to the Molecular Identification of a Bacterial Mechanosensitive Channel (1994) (51)
Studies of the cell surface of Paramecium. Ciliary membrane proteins and immobilization antigens. (1975) (51)
L596–W733 bond between the start of the S4–S5 linker and the TRP box stabilizes the closed state of TRPV4 channel (2015) (50)
Potassium Uptake Through the TOK1 K+ Channel in the Budding Yeast (1999) (50)
Slow inactivation of the calcium current of Paramecium is dependent on voltage and not internal calcium. (1985) (49)
Genetic Dissection of Active Electrogenesis in Paramecium aurelia (1974) (49)
Channels in microbes: so many holes to fill (2004) (48)
A mechanosensitive ion channel in Schizosaccharomyces pombe. (1992) (48)
Are ions involved in the gating of calcium channels? (1982) (48)
Microinjection of cytoplasm as a test of complementation in Paramecium (1982) (48)
Expression of the green fluorescent protein in Paramecium tetraurelia. (2000) (46)
Characterization and purification of a soluble protein controlling Ca-channel activity in paramecium (1984) (46)
A mutant Paramecium with a defective calcium-dependent potassium conductance has an altered calmodulin: a nonlethal selective alteration in calmodulin regulation. (1987) (45)
Yeast gain-of-function mutations reveal structure–function relationships conserved among different subfamilies of transient receptor potential channels (2007) (45)
Membrane currents of pawn mutants of the pwA group in Paramecium tetraurelia. (1980) (44)
Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids (2009) (43)
Osmotaxis in Escherichia coli. (1988) (42)
Heterologously expressed fungal transient receptor potential channels retain mechanosensitivity in vitro and osmotic response in vivo (2005) (40)
Chapter 3 Ca2+ Channels of Paramecium: A Multidisciplinary Study (1985) (39)
Mechanical Force and Cytoplasmic Ca2+ Activate Yeast TRPY1 in Parallel (2009) (39)
The cloning and molecular analysis of pawn-B in Paramecium tetraurelia. (2000) (39)
Forward Genetic Analysis Reveals Multiple Gating Mechanisms of TRPV4* (2010) (39)
Mutational alteration of membrane phospholipid composition and voltage-sensitive ion channel function in paramecium. (1981) (38)
An extensive behavioural and genetic analysis of the pawn mutants in Paramecium aurelia. (1974) (38)
The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae (1993) (37)
Interactions between gene products involved in divalent cation transport in Saccharomyces cerevisiae (1994) (36)
Ion channels in Paramecium, yeast and Escherichia coli. (1988) (36)
The cloning by complementation of the pawn-A gene in Paramecium. (1998) (36)
Helicity, membrane incorporation, orientation and thermal stability of the large conductance mechanosensitive ion channel from E. coli. (1998) (35)
Mutants with altered Ca2+-channel properties in Paramecium tetraurelia: isolation, characterization and genetic analysis. (1984) (35)
Structure of the recombinant Paramecium tetraurelia calmodulin at 1.68 A resolution. (1994) (35)
Patch clamp studies of microbial ion channels. (1992) (35)
Mechanosensitive Ion Channels in Bacteria (1992) (34)
A 'TEA+-insensitive' mutant with increased potassium conductance in Paramecium aurelia. (1976) (34)
Genetic analyses of "paranoiac" mutants of Paramecium tetraurelia. (1977) (33)
A mutant of Paramecium with increased relative resting potassium permeability. (1976) (32)
The use of yeast to understand TRP-channel mechanosensitivity (2009) (32)
Intra- and interspecific complementation of membrane-inexcitable mutants of Paramecium (1983) (31)
Microbial K+ Channels (2005) (31)
Patch Clamp and Phenotypic Analyses of a Prokaryotic Cyclic Nucleotide-gated K+ Channel Using Escherichia coli as a Host* (2007) (30)
Genetic analysis of mutants with a reduced Ca2+-dependent K+ current in Paramecium tetraurelia. (1985) (29)
An exchanger-like protein underlies the large Mg2+ current in Paramecium (2002) (29)
Genie Mutants with altered system of excitation in Paramecium aurelia (1971) (29)
Microbial mechanosensation (2005) (28)
Toward cloning genes by complementation in Paramecium. (1996) (28)
Efficient transformation of cam2, a behavioral mutant of Paramecium tetraurelia, with the calmodulin gene. (1991) (28)
The effect of sodium on "paranoiac"- a membrane mutant of Paramecium. (1976) (27)
Ba2+ influx measures the duration of membrane excitation in Paramecium. (1980) (27)
Chapter 12 Mechano-Sensitive Ion Channels in Microbes and the Early Evolutionary Origin of Solvent Sensing (1990) (26)
A new multigene family encoding calcium-dependent calmodulin-binding membrane proteins of Paramecium tetraurelia. (1999) (26)
Mutants in paramecium tetraurelia defective in their axonemal response to calcium. (1984) (25)
PAK Paradox: Paramecium Appears To Have More K+-Channel Genes than Humans (2003) (25)
Calcium-dependent inactivation of the calcium current activated upon hyperpolarization of Paramecium tetraurelia (1992) (25)
Voltage-sensitive ion channel ofEscherichia coli (1989) (24)
Genetic analysis of axonemal mutants in Paramecium tetraurelia defective in their response to calcium (1984) (24)
Genetic Analyses of Heat-Sensitve Pawn Mutants of PARAMECIUM AURELIA. (1973) (24)
MscL: a mechanosensitive channel in Escherichia coli. (1996) (23)
The ionic basis of the depolarizing mechanoreceptor potential of Paramecium tetraurelia (1983) (23)
K-resistant mutants and "adaptation" in Paramecium. (1978) (22)
Defective ion regulation in a class of membrane-excitation mutants in Paramecium. (1976) (22)
Isolation and characterization of paramecium mutants defective in their response to magnesium. (1994) (22)
Membrane excitability: made temperature-dependent by mutations. (1974) (21)
Multiple Unbiased Prospective Screens Identify TRP Channels and Their Conserved Gating Elements (2008) (21)
New non-lethal calmodulin mutations in Paramecium. A structural and functional bipartition hypothesis. (1994) (21)
Efficient expression of the Paramecium calmodulin gene in Escherichia coli after four TAA-to-CAA changes through a series of polymerase chain reactions. (1991) (21)
Antibodies to the ciliary membrane of Paramecium tetraurelia alter membrane excitability (1983) (21)
A single gene mutation that affects a potassium conductance and resting membrane potential in Paramecium. (1985) (19)
Biochemical characterization of a genetically altered calmodulin in Paramecium. (1987) (19)
Ion channels in Paramecium, yeast, and Escherichia coli. (1988) (18)
A channelopathy mechanism revealed by direct calmodulin activation of TrpV4 (2015) (18)
A competing hydrophobic tug on L596 to the membrane core unlatches S4–S5 linker elbow from TRP helix and allows TRPV4 channel to open (2016) (18)
A single amino acid substitution alters conductance and gating of OmpC porin of Escherichia coli. (1991) (18)
Indole and other aromatic compounds activate the yeast TRPY1 channel (2008) (18)
A Comparison of Internal Eliminated Sequences in the Genes that Encode Two K+‐Channel Isoforms in Paramecium tetraurelia (1998) (18)
Selection and analysis of a mutant Paramecium tetraurelia lacking behavioural response to tetraethylammonium. (1976) (17)
The core domain as the force sensor of the yeast mechanosensitive TRP channel (2011) (17)
A potassium conductance activated by hyperpolarization in paramecium (1978) (17)
Physiological and mutational protein variations in the ciliary membrane of Paramecium. (1983) (17)
The Electron Transport System of Kappa Particles from Paramecium aurelia Stock 51 (1970) (16)
Ionic channels of Paramecium: from genetics and electrophysiology to biochemistry. (1981) (16)
Characterization of cytoplasmic factors which complement Ca2+ channel mutations in Paramecium tetraurelia. (1984) (16)
Microbial TRP Channels and Their Mechanosensitivity (2007) (15)
A heat-induced depolarization ofParamecium and its relationship to thermal avoidance behavior (1983) (14)
Evidence for two K+ currents activated upon hyperpolarization ofParamecium tetraurelia (1990) (14)
A genome‐wide survey suggests an osmoprotective role for vacuolar Ca2+ release in cell wall‐compromised yeast (2008) (13)
Two quantitative assays for chemotaxis inParamecium (1975) (13)
Calmodulin defects cause the loss of Ca2+-dependent K+ currents in two pantophobiac mutants ofParamecium tetraurelia (1990) (12)
Purification of a soluble protein controlling ca channel activity in paramecium. (1984) (12)
Ion Channels of Three Microbes: Paramecium, Yeast and Escherichia Coli (1988) (12)
Ion Channels of Unicellular Microbes (1989) (12)
Aerobic Respiration of Kappa Particles from Paramecium aurelia, Stock 51* (1971) (11)
Osmotaxis in Escherichia coli. (1988) (11)
Solute Sensing vs. Solvent Sensing, A Speculation (1995) (11)
Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4. (2013) (11)
Lipid perturbations sensitize osmotic down‐shock activated Ca2+ influx, a yeast “deletome” analysis (2007) (11)
Mechanosensitive channels of E. coli: a genetic and molecular dissection. (1997) (10)
A regenerative hyperpolarization inParamecium (2004) (10)
A mutation that increases a novel calcium-activated potassium conductance ofParamecium tetraurelia (2005) (9)
Inhibition of Mg2+ current by single-gene mutation in Paramecium (1994) (9)
Primary mutations in calmodulin prevent activation of the Ca+ +‐dependent Na+ channel in Paramecium (1992) (8)
Recent advances in the molecular genetics of Paramecium. (2000) (8)
A mechanosensitive channel protein and its gene in E. coli. (1997) (8)
Genetic analysis of ion channels of prokaryotes and lower eukaryotes. (1992) (8)
Functional reconstitution of ion channels from Paramecium cortex into artificial liposomes (1995) (7)
Ion channels of microbes. (1994) (7)
K(+)-channel transgenes reduce K(+) currents in Paramecium, probably by a post-translational mechanism. (2001) (7)
Microbial Senses and Ion Channels (2008) (7)
Mechanosensitive Ion Channels in Cardiovascular Physiology (2014) (7)
Mutants with reduced Ca activation inParamecium aurelia (1976) (7)
Recent Advances in the Molecular Genetics of Paramecium1 (2000) (6)
Mutations resulting in resistance to polyene antibiotics decrease voltage-sensitive calcium channel activity in Paramecium. (1986) (6)
The force-from-lipid principle and its origin, a ‘what is true for E. coli is true for the elephant’ refrain (2022) (6)
A Genetic Dissection of Ion-Channel Functions (1998) (6)
Saccharomyces cerevisiae mutants sensitive to the antimalarial and antiarrhythmic drug, quinidine. (1994) (5)
Activities of a Mechanosensitive Ion Channel in anE. Coli Mutant Lacking the Major Lipoprotein (1993) (4)
Human mutations highlight an intersubunit cation–π bond that stabilizes the closed but not open or inactivated states of TRPV channels (2019) (4)
Mutant analysis shows that the Ca 2-induced K + current shuts off one type of excitation in Paramecium ( membrane excitation / behavioral mutant / prolonged action potential ) (4)
MUTANTS WITH ALTERED CA*+-CHANNEL PROPERTIES IN PARAMECIUM TETRAURELIA: ISOLATION, (1984) (4)
CHAPTER 28 – Calmodulin-Sensitive Channels (1994) (4)
K+ Channels: a Survey and a Case Study of Kch of Escherichia coli (2005) (4)
A single amino acid substitution alters conductance and gating of OmpC porin ofEscherichia coli (1991) (3)
Possible reduction of surface charge by a mutation inParamecium tetraurelia (1981) (3)
Interactions between mutants with defects in two Ca2+-dependent K+ currents ofParamecium tetraurelia (1990) (3)
CHAPTER 29 – Microbial Channels (1994) (3)
Behavioral Mutants of Paramecium Aurelia (1973) (3)
A calcium-dependent potassium current is increased by a single-gene mutation inParamecium (2005) (2)
Chapter 1 Ion Channels of Paramecium, Yeast, and Escherichia coli (1988) (2)
Genetic dissection of the excitable membrane of Paramecium. (1975) (2)
Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria (2004) (2)
Membrane Excitability : Made Temperature-Dependent by Mutations ( paramecium / electrophysiology / temperature-sensitive mutant ) (1)
Dissecting the Molecular Mechanism of How Force Activates Yeast TRP Channel TRPY1 (2010) (1)
MembraneExcitability: MadeTemperature-Dependent byMutations (1974) (0)
Forthcoming papers (2007) (0)
Chapter 15 A Genetic Dissection of Ion-Channel Functions (1988) (0)
OF TAXES IN PARAMECIUM (1982) (0)
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements (2014) (0)
Rotationand Twistof the Central-PairMicrotubules inthe Ciliaof Paramecium (1980) (0)
A Lipid-Exposed Residue at the Start of S4-S5 Linker Controls TRPV4 Gating (2016) (0)
Reply from Saimi et al. (1989) (0)
TRP Channels and Cell Mechanosensitivity (2011) (0)
Bilirubin-Induced Modulation of Cerebral Protein Phosphorylation in Neonate Rabbits in vivo (2016) (0)
MscL and related mechanosensitive ion-channel proteins (1999) (0)
Brief Review Microbial K (cid:1) Channels (2005) (0)
The L596-W733 Bond between S4-S5 Linker and TRP Domain Maintains Basal Activity and Enables Inactivation of TRPV4 (2015) (0)
Genetic Modification of Electric Propertie (2016) (0)
Key work: single gene mutation - potassium conductance -resting membrane potential -Paramecium (1985) (0)

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What Schools Are Affiliated With Chi-yun Kung?

Chi-yun Kung is affiliated with the following schools: