Charles Michael Stein
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(Suggest an Edit or Addition)Charles Michael Stein's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Premature coronary-artery atherosclerosis in systemic lupus erythematosus. (2003) (886)
- Atypical antipsychotic drugs and the risk of sudden cardiac death. (2009) (873)
- Azithromycin and the risk of cardiovascular death. (2012) (745)
- Molecular basis of ethnic differences in drug disposition and response. (2001) (596)
- Genetic determinants of response to warfarin during initial anticoagulation. (2008) (581)
- COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease (2002) (526)
- ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA “Boxed Warning”: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association (2010) (515)
- A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. (2008) (455)
- Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]. (1999) (410)
- The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. (2001) (379)
- Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factors. (2005) (365)
- Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis. (2008) (356)
- Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process (2014) (346)
- Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update (2019) (331)
- CYP2C9 allelic variants: ethnic distribution and functional significance. (2002) (329)
- Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study (2002) (318)
- Antibiotics; adverse effects: Oral erythromycin and the risk of sudden death from cardiac causes (2004) (314)
- Genetic variability in CYP3A5 and its possible consequences. (2004) (313)
- Drugs That May Cause or Exacerbate Heart Failure: A Scientific Statement From the American Heart Association. (2016) (294)
- An automated database case definition for serious bleeding related to oral anticoagulant use (2011) (290)
- CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5′‐promoter region polymorphism (2000) (278)
- Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain. (2016) (274)
- Role of inflammation and oxidative stress in atrial fibrillation. (2009) (271)
- Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans. (2001) (267)
- Outcomes With Concurrent Use of Clopidogrel and Proton-Pump Inhibitors (2010) (249)
- Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing (2010) (223)
- Inflammation-associated insulin resistance: differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms. (2008) (221)
- Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis. (2009) (214)
- Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis. (2009) (209)
- Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world. (1999) (191)
- Antipsychotics and the risk of type 2 diabetes mellitus in children and youth. (2013) (190)
- Bradykinin stimulates tissue plasminogen activator release in human vasculature. (1999) (167)
- Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. (1996) (161)
- Pharmacogenomics: The Genetics of Variable Drug Responses (2011) (151)
- ADHD drugs and serious cardiovascular events in children and young adults. (2011) (147)
- Cardiovascular Risks of Nonsteroidal Antiinflammatory Drugs in Patients After Hospitalization for Serious Coronary Heart Disease (2009) (145)
- Obesity is an independent contributor to functional capacity and inflammation in systemic lupus erythematosus. (2005) (143)
- Increased Vascular Adrenergic Vasoconstriction and Decreased Vasodilation in Blacks: Additive Mechanisms Leading to Enhanced Vascular Reactivity (2000) (143)
- Assessment of Adherence to and Persistence on Disease-Modifying Antirheumatic Drugs (DMARDs) in Patients With Rheumatoid Arthritis (2007) (136)
- Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding (2018) (132)
- Increased concentration of proatherogenic inflammatory cytokines in systemic lupus erythematosus: relationship to cardiovascular risk factors. (2006) (131)
- Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study ☆ (2002) (128)
- Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals. (1999) (125)
- Attenuation of isoproterenol-mediated vasodilatation in blacks. (1995) (125)
- Reform of drug regulation--beyond an independent drug-safety board. (2006) (123)
- Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. (2009) (123)
- Novel cardiovascular risk factors in premature coronary atherosclerosis associated with systemic lupus erythematosus. (2008) (117)
- Making medicines safer--the need for an independent drug safety board. (1998) (114)
- Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis (2006) (110)
- Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. (2001) (105)
- Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study. (2002) (104)
- The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients (2012) (104)
- Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature. (1998) (103)
- Inhibition of stimulated interleukin-2 production in whole blood: a practical measure of cyclosporine effect. (1999) (99)
- Outpatient Opioid Prescriptions for Children and Opioid-Related Adverse Events (2018) (99)
- Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy. (2011) (95)
- Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension. (1995) (95)
- Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. (2007) (87)
- Clopidogrel and the Concept of High-Risk Pharmacokinetics (2009) (86)
- Increased oxidative stress in patients with depression and its relationship to treatment (2013) (85)
- Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy. (2009) (83)
- Why randomized controlled clinical trials do not depict accurately long-term outcomes in rheumatoid arthritis: some explanations and suggestions for future studies. (1997) (80)
- Serum osteoprotegerin is increased and independently associated with coronary-artery atherosclerosis in patients with rheumatoid arthritis. (2007) (79)
- A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade. (2003) (78)
- Drugs Used in the Treatment of Rheumatoid Arthritis: Relationship between Current Use and Cardiovascular Risk Factors (2009) (78)
- COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease☆ (2003) (77)
- Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus. (2006) (77)
- Clinical and Genetic Determinants of Warfarin Pharmacokinetics and Pharmacodynamics during Treatment Initiation (2011) (75)
- Changing patterns of medication use in patients with rheumatoid arthritis in a Medicaid population. (2008) (74)
- Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases (2018) (70)
- Atherosclerosis and inflammation: insights from rheumatoid arthritis (2007) (70)
- Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy (2011) (69)
- Association of Proton Pump Inhibitors With Reduced Risk of Warfarin-Related Serious Upper Gastrointestinal Bleeding. (2016) (69)
- Adipocytokines, insulin resistance, and coronary atherosclerosis in rheumatoid arthritis. (2010) (68)
- Out-of-hospital mortality among patients receiving methadone for noncancer pain. (2015) (68)
- Increased augmentation index in rheumatoid arthritis and its relationship to coronary artery atherosclerosis. (2007) (67)
- Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. (2002) (67)
- Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent. (1999) (66)
- Opioid Analgesics and the Risk of Serious Infections Among Patients With Rheumatoid Arthritis: A Self‐Controlled Case Series Study (2016) (66)
- β2-Adrenergic receptor genotype and preterm delivery ☆ ☆☆ (2002) (66)
- Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths (2019) (63)
- Placebo-controlled studies in rheumatoid arthritis: ethical issues (1999) (62)
- Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. (2020) (62)
- Effect of omega-three polyunsaturated fatty acids on inflammation, oxidative stress, and recurrence of atrial fibrillation. (2015) (60)
- Cardiovascular toxicity of valdecoxib. (2004) (58)
- LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins (2018) (58)
- No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia. (2004) (58)
- Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension. (1999) (57)
- Brief Report: The Ability of the 2013 American College of Cardiology/American Heart Association Cardiovascular Risk Score to Identify Rheumatoid Arthritis Patients With High Coronary Artery Calcification Scores (2015) (56)
- Effects of anti-tumor necrosis factor &agr; agents on bone (2012) (55)
- Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade (2008) (55)
- Genotype and risk of major bleeding during warfarin treatment. (2014) (54)
- Oxidative stress in fibromyalgia and its relationship to symptoms (2009) (52)
- ACR 20: clinical or statistical significance? (1999) (52)
- Utility of a novel inflammatory marker, GlycA, for assessment of rheumatoid arthritis disease activity and coronary atherosclerosis (2015) (52)
- Amino-terminal fragment of the prohormone brain-type natriuretic peptide in rheumatoid arthritis. (2008) (52)
- In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism. (2001) (52)
- A computer case definition for sudden cardiac death (2009) (51)
- Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis (2015) (51)
- A genetic risk score that includes common type 2 diabetes risk variants is associated with gestational diabetes (2017) (49)
- Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard. (1997) (49)
- Are Long-Term Very Low Doses of Prednisone for Patients with Rheumatoid Arthritis as Helpful as High Doses Are Harmful? (2002) (49)
- Validation of discharge diagnosis codes to identify serious infections among middle age and older adults (2018) (48)
- Non-steroidal antiinflammatory drugs and risk of serious coronary heart disease (2002) (47)
- The aprotinin story--is BART the final chapter? (2008) (47)
- Computerized definitions showed high positive predictive values for identifying hospitalizations for congestive heart failure and selected infections in Medicaid enrollees with rheumatoid arthritis (2008) (47)
- Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update (2022) (46)
- Lipoprotein Subclasses Determined by Nuclear Magnetic Resonance Spectroscopy and Coronary Atherosclerosis in Patients with Rheumatoid Arthritis (2010) (46)
- Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis (2011) (46)
- Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study. (2018) (45)
- Cyclosporine impairs vasodilation without increased sympathetic activity in humans. (1995) (44)
- Utility of Select Plasma MicroRNA for Disease and Cardiovascular Risk Assessment in Patients with Rheumatoid Arthritis (2015) (44)
- Initiation of Tumor Necrosis Factor α Antagonists and Risk of Fractures in Patients With Selected Rheumatic and Autoimmune Diseases (2013) (44)
- Interactive Effect of Ethnicity and ACE Insertion/Deletion Polymorphism on Vascular Reactivity (2001) (42)
- CYP2A6 genetic variation and dexmedetomidine disposition (2012) (42)
- What is the best source of useful data on the treatment of rheumatoid arthritis: clinical trials, clinical observations, or clinical protocols? (1995) (41)
- "No evidence of disease" in rheumatoid arthritis using methotrexate in combination with other drugs: a contemporary goal for rheumatology care? (1997) (41)
- Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses (2003) (39)
- Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo. (2004) (39)
- Time-trends in gastroprotection with NSAIDs (2010) (39)
- Ethnic and Genetic Determinants of Cardiovascular Response to the Selective &agr;2-Adrenoceptor Agonist Dexmedetomidine (2008) (38)
- Combination treatment of severe rheumatoid arthritis with cyclosporine and methotrexate for forty-eight weeks: an open-label extension study. The Methotrexate-Cyclosporine Combination Study Group. (1997) (38)
- Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine (1996) (38)
- Atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus. (2008) (38)
- Genetic and Clinical Risk Prediction Model for Postoperative Atrial Fibrillation (2015) (38)
- Beta2 adrenoceptor THR164ILE polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo (2003) (36)
- Inflammation and Hypertension in Rheumatoid Arthritis (2013) (36)
- Consortium ( CPIC ) guidelines for cytochrome P 450-2 C 19 ( CYP 2 C 19 ) genotype and clopidogrel therapy (2011) (35)
- Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks. (1997) (35)
- Inflammatory mechanisms affecting the lipid profile in patients with systemic lupus erythematosus. (2007) (35)
- Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race. (2001) (34)
- Peroxisome proliferator-activated receptor γ agonist effect on rheumatoid arthritis: a randomized controlled trial (2013) (34)
- Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection (2019) (34)
- Heart Failure Risk Associated With Rheumatoid Arthritis–Related Chronic Inflammation (2020) (32)
- The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population (2014) (32)
- beta2-Adrenergic receptor genotype and preterm delivery. (2002) (31)
- Meta-analysis of genome-wide association studies of HDL cholesterol response to statins (2016) (31)
- Population Pharmacokinetics of Fentanyl in the Critically Ill* (2016) (31)
- Epicardial adipose tissue is increased in patients with systemic lupus erythematosus. (2012) (30)
- Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers. (2003) (30)
- The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy (2016) (29)
- G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy. (2003) (29)
- High-Sensitivity Cardiac Troponin-I Is Elevated in Patients with Rheumatoid Arthritis, Independent of Cardiovascular Risk Factors and Inflammation (2012) (29)
- Association of Rivaroxaban vs Apixaban With Major Ischemic or Hemorrhagic Events in Patients With Atrial Fibrillation. (2021) (29)
- Aspirin therapy and thromboxane biosynthesis in systemic lupus erythematosus (2007) (28)
- Dietary sodium intake modulates vasodilation mediated by nitroprusside but not by methacholine in the human forearm. (1995) (26)
- Endothelial Function in Systemic Lupus Erythematosus: Relationship to Disease Activity, Cardiovascular Risk Factors, Corticosteroid Therapy, and Coronary Calcification (2005) (26)
- Development and Validation of a MicroRNA Panel to Differentiate Between Patients with Rheumatoid Arthritis or Systemic Lupus Erythematosus and Controls (2020) (26)
- Cardiovascular Effects of Noncardiovascular Drugs (2009) (25)
- Effect of the VKORC1 D36Y variant on warfarin dose requirement and pharmacogenetic dose prediction (2012) (25)
- Insulin Resistance is Associated with Increased Concentrations of NT-proBNP in Rheumatoid Arthritis: IL-6 as a Potential Mediator (2013) (25)
- N-terminal pro-brain natriuretic peptide in systemic lupus erythematosus: relationship with inflammation, augmentation index, and coronary calcification. (2008) (25)
- Desensitization of vascular response in vivo: contribution of genetic variation in the α2B-adrenergic receptor subtype (2010) (24)
- Variations in the alpha2A-adrenergic receptor gene and their functional effects. (2006) (24)
- Sympathoinhibitory response to clonidine is blunted in patients with heart failure. (1997) (24)
- Alpha2-Adrenergic Receptor–Induced Vascular Constriction in Blacks and Whites (2004) (24)
- Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans (2011) (24)
- Free fatty acids are associated with insulin resistance but not coronary artery atherosclerosis in rheumatoid arthritis. (2011) (24)
- High frequency of use of rofecoxib at greater than recommended doses: cause for concern (2004) (24)
- Genetic Variations in the &agr;2A-Adrenoreceptor Are Associated With Blood Pressure Response to the Agonist Dexmedetomidine (2011) (24)
- Exploring the Lipid Paradox Theory in Rheumatoid Arthritis: Associations of Low Circulating Low‐Density Lipoprotein Concentration With Subclinical Coronary Atherosclerosis (2019) (23)
- Lack of correlation between arterial and venous beta-adrenergic receptor sensitivity. (1997) (22)
- Neuropsychometric correlates of efavirenz pharmacokinetics and pharmacogenetics following a single oral dose. (2013) (21)
- GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans. (2009) (21)
- Cystatin C, Renal Function, and Atherosclerosis in Rheumatoid Arthritis (2011) (20)
- Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records (2018) (20)
- Association of foot ulcer with tibial artery calcification is independent of peripheral occlusive disease in type 2 diabetes. (2013) (20)
- Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases (2018) (19)
- The ethics of placebo in studies with fracture end points in osteoporosis. (2010) (19)
- Disproportionate Decrease in &agr;- Compared With &bgr;-Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation (2002) (19)
- A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR (2019) (19)
- Effect of SLCO1B1 Polymorphisms on High‐Dose Methotrexate Clearance in Children and Young Adults With Leukemia and Lymphoblastic Lymphoma (2020) (18)
- Changes in cotherapies after initiation of disease‐modifying antirheumatic drug therapy in patients with rheumatoid arthritis (2011) (18)
- Positive predictive value of a case definition for diabetes mellitus using automated administrative health data in children and youth exposed to antipsychotic drugs or control medications: a Tennessee Medicaid study (2012) (18)
- Plasma miRNAs improve the prediction of coronary atherosclerosis in patients with rheumatoid arthritis (2021) (17)
- Blacks Have a Greater Sensitivity to &agr;1-Adrenoceptor–Mediated Venoconstriction Compared With Whites (2013) (17)
- Effect of the α2C-adrenoreceptor deletion322–325 variant on sympathetic activity and cardiovascular measures in healthy subjects (2007) (17)
- The Gly389Arg β1‐adrenergic receptor polymorphism: A predictor of response to β‐blocker treatment? (2003) (16)
- A retrospective approach to evaluating potential adverse outcomes associated with delay of procedures for cardiovascular and cancer-related diagnoses in the context of COVID-19 (2020) (16)
- PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records (2020) (16)
- Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise (2012) (16)
- Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways. (2020) (15)
- Effects of C-reactive Protein and Homocysteine on Cytokine Production: Modulation by Pravastatin (2008) (15)
- Individual short‐acting opioids and the risk of opioid‐related adverse events in adolescents (2019) (15)
- Modeling drug exposure data in electronic medical records: an application to warfarin. (2011) (15)
- High-Dose Citalopram and Escitalopram and the Risk of Out-of-Hospital Death. (2017) (15)
- α2B Adrenergic receptor 301-303 deletion polymorphism and vascular α2 adrenergic receptor response (2005) (15)
- β2-Adrenoceptor Genotype and Function Affect Hemodynamic Profile Heterogeneity in Postural Tachycardia Syndrome (2006) (15)
- Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis. (2016) (15)
- High-density lipoprotein function in rheumatoid arthritis (2016) (15)
- Increased Incidence of Resistant Hypertension in Patients With Systemic Lupus Erythematosus: A Retrospective Cohort Study (2020) (15)
- Urinary Albumin Excretion Is Increased in Patients with Rheumatoid Arthritis and Associated with Arterial Stiffness (2015) (14)
- Alpha 1A-adrenergic receptor polymorphism and vascular response. (2004) (14)
- Effect of combination therapy with cyclosporine and methotrexate on liver function test results in rheumatoid arthritis. (1997) (14)
- Absence of Fibrosis and Inflammation by Cardiac Magnetic Resonance Imaging in Rheumatoid Arthritis Patients with Low to Moderate Disease Activity (2018) (14)
- A Mendelian Randomization Approach Using 3-HMG-Coenzyme-A Reductase Gene Variation to Evaluate the Association of Statin-Induced Low-Density Lipoprotein Cholesterol Lowering With Noncardiovascular Disease Phenotypes (2021) (13)
- Identifying genetically driven clinical phenotypes using linear mixed models (2016) (13)
- Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep. (1998) (13)
- Norepinephrine release in the human forearm: effects of epinephrine. (1997) (13)
- Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study (2019) (13)
- Combination treatment of rheumatoid arthritis with cyclosporine and methotrexate. (1999) (13)
- A Genetic Approach to the Association Between PCSK9 and Sepsis (2019) (13)
- Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo (2011) (13)
- A Variant in the Osteoprotegerin Gene Is Associated with Coronary Atherosclerosis in Patients with Rheumatoid Arthritis: Results from a Candidate Gene Study (2015) (12)
- Genetic variation in the β1-adrenergic receptor is associated with the risk of atrial fibrillation after cardiac surgery. (2014) (12)
- Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response. (2005) (12)
- Pharmacogenetics and Response to β‐adrenergic Receptor Antagonists in Heart Failure (2005) (12)
- Cyclosporine-induced alterations in renal function are not associated with lipid peroxidation. (1994) (11)
- A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers (2018) (11)
- The Endogenous Plasma Small RNAome of Rheumatoid Arthritis (2020) (11)
- Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol. (1995) (11)
- Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins (2014) (11)
- Validation of a computer case definition for sudden cardiac death in opioid users (2012) (11)
- Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment. (2016) (10)
- Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension (2022) (10)
- Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise. (2015) (10)
- Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population (2017) (10)
- Variation in the &agr;2A adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose (2013) (10)
- Suboptimal Inhibition of Platelet Cyclooxygenase 1 by Aspirin in Systemic Lupus Erythematosus: Association With Metabolic Syndrome (2014) (10)
- A unified framework identifies novel links between plasma lipids and diseases from electronic medical records across large-scale cohorts (2021) (9)
- GENETIC VARIATION IN THE α1A-ADRENERGIC RECEPTOR AND PHENYLEPHRINE-MEDIATED VENOCONSTRICTION (2014) (9)
- Co‐Prescription of Strong CYP1A2 Inhibitors and the Risk of Tizanidine‐Associated Hypotension: A Retrospective Cohort Study (2018) (9)
- Mortality and concurrent use of opioids and hypnotics in older patients: A retrospective cohort study (2021) (9)
- Comparative out‐of‐hospital mortality of long‐acting opioids prescribed for non‐cancer pain: A retrospective cohort study (2018) (9)
- A Bayesian hierarchical nonlinear mixture model in the presence of artifactual outliers in a population pharmacokinetic study (2011) (9)
- Drugs to Treat Systemic Lupus Erythematosus: Relationship between Current Use and Cardiovascular Risk Factors (2008) (9)
- GENETIC VARIATION IN THE ALPHA1B - ADRENERGIC RECEPTOR AND VASCULAR RESPONSE (2016) (9)
- Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients. (2021) (9)
- Replication and fine-mapping of genetic predictors of lipid traits in African-Americans (2017) (8)
- Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome‐Wide Association Study and Inverse Variance–Weighted Meta‐Analysis (2020) (8)
- Beta2-adrenoceptor genotype and function affect hemodynamic profile heterogeneity in postural tachycardia syndrome. (2006) (7)
- The polygenic architecture of left ventricular mass mirrors the clinical epidemiology (2020) (7)
- Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus (2022) (7)
- Alpha2A adrenergic receptor genetic variation contributes to hyperglycemia after myocardial infarction. (2016) (7)
- Circulating microbial small RNAs are altered in patients with rheumatoid arthritis (2020) (7)
- The Gly389Arg beta1-adrenergic receptor polymorphism: a predictor of response to beta-blocker treatment? (2003) (7)
- Vascular Alpha-1 Adrenergic Sensitivity is Enhanced in Chronic Kidney Disease. (2019) (7)
- Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis (2018) (6)
- Ambulatory blood pressure in patients with systemic lupus erythematosus: Association with markers of immune activation (2020) (6)
- Genetics Primer for the General Cardiologist Pharmacogenomics The Genetics of Variable Drug Responses (2011) (6)
- Pharmacogenetics and rheumatology: Molecular mechanisms contributing to variability in drug response. (2005) (6)
- Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women (2005) (6)
- DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions (2021) (6)
- Variants in BMI‐Associated Genes and Adrenergic Genes are not Associated with Gestational Weight Trajectory (2019) (6)
- Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting. (2014) (6)
- A polymorphism in the protein kinase C gene PRKCB is associated with &agr;2-adrenoceptor-mediated vasoconstriction (2013) (6)
- Basal and stimulated sympathetic responses after epinephrine: no evidence of augmented responses. (1998) (5)
- Increased Vascular Alpha-1 Adrenergic Receptor Sensitivity in Older Adults with Post-traumatic Stress Disorder. (2020) (5)
- Genetic determinants of variability in warfarin response after the dose-titration phase (2016) (5)
- Combining Clinical and Candidate Gene Data into a Risk Score for Azathioprine-Associated Leukopenia in Routine Clinical Practice (2020) (5)
- The effect of sildenafil on QT interval in healthy men (2001) (5)
- Change in mRNA Expression after Atenolol, a Beta-adrenergic Receptor Antagonist and Association with Pharmacological Response (2009) (4)
- Pharmacogenetics of Hypoglycemia Associated with Sulfonylurea Therapy in Usual Clinical Care (2020) (4)
- High-throughput framework for genetic analyses of adverse drug reactions using electronic health records (2021) (4)
- Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for thiopurine methyltransferase (TPMT) genotype and thiopurine dosing (2011) (4)
- Polygenic Risk Score to Identify Subclinical Coronary Heart Disease Risk in Young Adults (2021) (4)
- β-Adrenergic Receptors (2012) (4)
- Race, Genotype, and Azathioprine Discontinuation (2022) (4)
- Variation in the α2A-adrenergic receptor gene and risk of gestational diabetes. (2017) (3)
- Independent Regulation of Alpha 1 and Alpha 2 Adrenergic Receptor – Mediated Vasoconstriction in vivo (2010) (3)
- Alpha 2-Adrenergic Receptor – Induced Vascular Constriction in Blacks and Whites (2003) (3)
- WARFARIN DOSING ALGORITHM REFINEMENTS AFTER 7-9 DAYS OF THERAPY BASED ON PHARMACOGENETIC, PHARMACOKINETIC, CLINICAL, AND LABORATORY DATA (2010) (3)
- The α2C-adrenoceptor deletion322–325 variant and cold-induced vasoconstriction (2009) (3)
- Oxidative stress, microvascular dysfunction, and scleroderma: an association with potential therapeutic implications, a commentary on "Postocclusive reactive hyperemia inversely correlates with urinary 15-F2t-isoprostane levels in systemic sclerosis". (2006) (2)
- Identification and Functional Characterization of a New CYP 2 C 9 Variant ( CYP 2 C 9 * 51 ) Expressed among African Americans (2001) (2)
- G-protein β-3 subunit 825C/T polymorphism is associated with weight gain in pregnancy but not with preeclampsia (2001) (2)
- Principles of Pharmacogenetics and Pharmacogenomics: Pharmacogenetics and Pharmacogenomics of Cardiovascular Disease (2012) (2)
- Attenuation of Isoproterenol-Mediated Vasodilatation in Blacks: response from authors. (1995) (2)
- Amino-Terminal Fragment of the Prohormone Brain-type Natriuretic Peptide (NT-proBNP) in Rheumatoid Arthritis (2011) (2)
- Academic clinical research: Death by a thousand clicks (2015) (2)
- CYP2D6 GENOTYPE AND REDUCED CODEINE ANALGESIC EFFECT IN REAL-WORLD CLINICAL PRACTICE (2021) (2)
- Co‐Administration of Glyburide and Minoxidil, Drugs with Opposing Effects on Potassium Channels (1996) (1)
- Sympathetic activation in the elderly: is it due to impaired alpha adrenergic feedback sympathoinhibition? (1997) (1)
- Cyclosporine in the treatment of rheumatoid arthritis. (1995) (1)
- Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity (2022) (1)
- Immunodeficient states and associated rheumatic manifestations. (1996) (1)
- Genetic Variations in the . 2A-adrenoreceptor Are Associated with Blood (2017) (1)
- Validation of a computer case definition for sudden cardiac death in opioid users (2012) (1)
- Disproportionate Decrease in-Compared With -Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation (2002) (1)
- Oxidative stress in systemic lupus erythematous: comment on the article by Wang et al. (2010) (1)
- Opioid Analgesics and the Risk of Serious Infections among Older Adults (2015) (1)
- Abstract 15433: Lpa Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins Abstract (2017) (1)
- Placebo-Controlled Fracture Trials in Osteoporosis — Comment on the Article by Rosen and Khosla (2010) (1)
- Beta‐2 Adrenergic Receptor (BAR2) Poly‐morphism is Not Associated with Essential Hypertension (HT) in African‐Americans (AA) or Caucasian‐Americans (CA) (1999) (1)
- Is Visceral Fat the Missing Link in the Relationship Between Inflammation and Insulin Resistance in RA? (2014) (1)
- Archives of Drug Information—A New Approach to Publishing the Results of Drug Studies (2008) (0)
- Genetic susceptibility for autoimmune diseases and white blood cell count (2023) (0)
- Duloxetine, Gabapentin, and the Risk for Acute Myocardial Infarction, Stroke, and Out-of-Hospital Death in Medicare Beneficiaries With Non-Cancer Pain (2023) (0)
- Polymorphisms in VKORC1, CYP2C9, and CYP4F2 and Warfarin Dose in the Pediatric Population (2012) (0)
- Corrigendum to “Epicardial adipose tissue is increased in patients with systemic lupus erythematosus” [Atherosclerosis 223 (2) (2013) 389–393] (2013) (0)
- Differences in the frequency of Arg492⇒Cys polymorphism of the human α1A‐adrenergic receptor (α1A‐AR) in African‐Americans (AA) and Caucasians (CA) (1999) (0)
- Ethnicity And Systemic Effects Of Dexmedetomidine, A Specific Adrenergic α: Piii-8-receptor Agonist: Piii-8 (2006) (0)
- The effect of bosentan on endothelial function in patients with congestive heart failure (2005) (0)
- Interethnic Differences in Beta‐2 Adrenoceptor (BAR2) Polymorphisms in African‐American (AA), Caucasian (CA), and Chinese (CHN) Populations (1999) (0)
- Atherosclerosis and Tissue Injury in Systemic Lupus Erythematosus (2011) (0)
- Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosus (2019) (0)
- Abstract 490: Amitriptyline Activates Cardiac Ryanodine Receptors Independently of its Action on Cardiac Calsequestrin - Role for Amitriptyline Linked Sudden Cardiac Death (2007) (0)
- Phenome-Wide Association Study of UMOD Gene Variants and Differential Associations With Clinical Outcomes Across Populations in the Million Veteran Program a Multiethnic Biobank (2022) (0)
- A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR (2019) (0)
- The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach (2023) (0)
- Alpha‐2B adrenergic receptor (ADRA2B) 301‐303 deletion polymorphism and vascular desensitization in vivo (2004) (0)
- AB0417 Exercise is associated with decreased risk of metabolic syndrome in patients with sle (2013) (0)
- A High-Throughput Genetic Analysis of Common Drug Allergy Labels Using Data from a Large Biobank (2018) (0)
- Effect of alpha‐2C adrenergic receptor (ADRA2C) 322–325 deletion polymorphism on blood pressure response to dietary sodium in African‐Americans (AA) (2004) (0)
- Reply (2010) (0)
- Abstract 19814: Patients with Rheumatoid Arthritis Have Elevated High-Sensitivity Cardiac Troponin-I Concentrations Independent of Cardiovascular Risk Factors and Inflammation (2010) (0)
- Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice (2020) (0)
- Toxicity of combination therapies in rheumatoid arthritis: comment on the article by Willkens et al. (1996) (0)
- Reply to “commentary…” (2010) (0)
- Sequence analysis of the α2B‐ADRENERGIC receptor (ADRA2B) gene and in‐vivo functional effects of novel variants (2005) (0)
- Association Between Genetically Predicted Expression of TPMT and Azathioprine Adverse Events (2023) (0)
- ASSOCIATION OF THE G-PROTEIN β-3 SUBUNIT 825C/T POLYMORPHISM AND WEIGHT GAIN IN PREGNANCY A49 (Poster 39) (2001) (0)
- after cessation of prostacyclin infusion in sheep Angiotensin II mediates systemic rebound hypertension (2015) (0)
- Mechanisms Underlying Greater Propensity for Cardiovascular Disease in High Risk Populations Vascular 1-adrenergic sensitivity is enhanced in chronic kidney disease (2019) (0)
- Pharmacogenetics of hypoglycemia associated with sulfonylurea therapy in usual clinical care (2020) (0)
- The Journal of Rheumatology Volume 42 , no . 4 and Associated with Arterial Stiffness Urinary Albumin Excretion Is Increased in Patients with Rheumatoid Arthritis (2015) (0)
- Validating Data-Driven Clinical Fingerprints as an Input Feature Representation (2022) (0)
- Abstract 2378: Genetics of the Initial Anticoagulant Response to Warfarin - a Prospective Study (2006) (0)
- Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis (2021) (0)
- PI‐28 (2006) (0)
- Abstract 19370: Myocardial Extracellular Volume is Elevated in Human Duchenne Muscular Dystrophy (2014) (0)
- Rooted in risk ; genetic predisposition for LDL-c level associates with diminished LDL-c response to statin treatment (2016) (0)
- Reply (2004) (0)
- A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers (2018) (0)
- Abstract 16172: Association of Genetic Variation in the α2A-adrenergic Receptor Gene With Risk of Gestational Diabetes (2016) (0)
- Identifying Potential Therapeutic Applications and Diagnostic Harms of Increased Bilirubin Concentrations: A Clinical and Genetic Approach (2021) (0)
- Vascular Response To Isoproterenol In Pregnancy A33 (2000) (0)
- Insulin Resistance in RA ? Is Visceral Fat the Missing Link in the Relationship Between Inflammation and (2014) (0)
- Association between APOL1 risk variants and progression from infection to sepsis (2023) (0)
- Multi-system diseases and infections (2014) (0)
- Guidelines for CYP 2 C 9 and VKORC 1 Genotypes and Warfarin Dosing – ONLINE SUPPLEMENT (2011) (0)
- Abstract 415: HDL-small RNA Gene Regulatory Networks Alter T Cell Signalling (2018) (0)
- Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study (2019) (0)
- Response to Is Creatine Kinase the Intrinsic Factor of Smooth Muscle Enhancing Vascular Contractility in Subjects of African Ancestry (2013) (0)
- Alpha‐2C adrenergic receptor (ADRA2C) 322‐325 deletion polymorphism and in vivo vascular sensitivity (2004) (0)
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What Schools Are Affiliated With Charles Michael Stein?
Charles Michael Stein is affiliated with the following schools:
