Christoph Richter
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Christoph Richterbiology Degrees
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Cell Biology
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Molecular Biology
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Biochemistry
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Chemistry Biology
Christoph Richter's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Chemistry Stanford University
- Bachelors Chemistry Stanford University
Why Is Christoph Richter Influential?
(Suggest an Edit or Addition)Christoph Richter's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Normal oxidative damage to mitochondrial and nuclear DNA is extensive. (1988) (1723)
- Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions (1998) (662)
- Superoxide radicals as precursors of mitochondrial hydrogen peroxide (1974) (613)
- Nitric oxide synthase activity in mitochondria (1997) (568)
- Oxidants in mitochondria: from physiology to diseases. (1995) (545)
- Control of apoptosis by the cellular ATP level (1996) (465)
- ADP-ribosylation of proteins. Enzymology and biological significance. (2012) (355)
- Oxidative damage to mitochondrial DNA and its relationship to ageing. (1995) (353)
- Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation. (1999) (332)
- Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. (1994) (322)
- The use of acetylated ferricytochrome c for the detection of superoxide radicals produced in biological membranes. (1975) (303)
- Oxidative stress in mitochondria: its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation. (1991) (295)
- Ceramide Induces Cytochrome c Release from Isolated Mitochondria (1999) (268)
- Age-related Macular Degeneration (2000) (266)
- Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells (1993) (261)
- Pro‐oxidants and mitochondrial Ca2+: their relationship to apoptosis and oncogenesis (1993) (250)
- Biophysical consequences of lipid peroxidation in membranes. (1987) (240)
- Reactive oxygen and DNA damage in mitochondria. (1992) (233)
- Do mitochondrial DNA fragments promote cancer and aging? (1988) (229)
- Mitochondrial Creatine Kinase Is a Prime Target of Peroxynitrite-induced Modification and Inactivation* (1998) (200)
- Hydroperoxide-induced loss of pyridine nucleotides and release of calcium from rat liver mitochondria. (1980) (187)
- Hydroperoxides can modulate the redox state of pyridine nucleotides and the calcium balance in rat liver mitochondria. (1979) (182)
- Ca2+ release from mitochondria induced by prooxidants. (1988) (157)
- Microsomal lipid peroxidation causes an increase in the order of the membrane lipid domain (1982) (146)
- Ceramide induces cytochrome c release from isolated mitochondria. (1999) (109)
- The early phase of glucose-stimulated insulin secretion requires nitric oxide (1998) (100)
- Reactive Oxygen and Nitrogen Species Regulate Mitochondrial Ca2+ Homeostasis and Respiration (1997) (98)
- Menadione- (2-methyl-1,4-naphthoquinone-) dependent enzymatic redox cycling and calcium release by mitochondria. (1986) (97)
- Rotation of cytochrome P-450. I. Investigations of protein-protein interactions of cytochrome P-450 in phospholipid vesicles and liver microsomes. (1982) (95)
- The energy-state of mitochondria during the transport of Ca2+. (1980) (95)
- Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells. (2000) (95)
- Nitric oxide kills hepatocytes by mobilizing mitochondrial calcium. (1994) (91)
- Mitochondrial calcium release induced by prooxidants. (1993) (91)
- Nitric oxide (nitrogen monoxide, NO) stimulates insulin secretion by inducing calcium release from mitochondria. (1995) (90)
- Mitochondrial Nitric Oxide Synthase, Oxidative Stress and Apoptosis (2001) (90)
- Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolites (1990) (88)
- Peroxynitrite formed by mitochondrial NO synthase promotes mitochondrial Ca2+ release. (2000) (84)
- Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro. (2002) (77)
- N‐Methyl‐4‐phenylpyridine (MMP+ together with 6‐hydroxydopamine or dopamine stimulates Ca2+ release from mitochondria (1986) (75)
- Reactivity of antiinflammatory and superoxide dismutase active Cu(II)-salicylates. (1978) (72)
- Rotation of cytochrome P-450. II. Specific interactions of cytochrome P-450 with NADPH-cytochrome P-450 reductase in phospholipid vesicles. (1982) (72)
- Inactivation of NADP(+)-dependent isocitrate dehydrogenase by nitric oxide. (2002) (71)
- Mitochondrial Nitric Oxide Synthase Regulates Mitochondrial Matrix pH (1999) (68)
- Mechanism of alloxan-induced calcium release from rat liver mitochondria. (1985) (66)
- ATP prevents both hydroperoxide-induced hydrolysis of pyridine nucleotides and release of calcium in rat liver mitochondria. (1981) (62)
- Rotation of cytochrome P-450. Complex formation of cytochrome P-450 with NADPH-cytochrome P-450 reductase in liposomes demonstrated by combining protein rotation with antibody-induced cross-linking. (1983) (61)
- 'Pore' formation is not required for the hydroperoxide-induced Ca2+ release from rat liver mitochondria. (1992) (60)
- ADP-ribosylation in inner membrane of rat liver mitochondria. (1983) (60)
- Peroxynitrite Stimulates the Pyridine Nucleotide-Linked Ca2+ Release from Intact Rat Liver Mitochondria† (1996) (59)
- The hydroperoxide‐induced release of mitochondrial calcium occurs via a distinct pathway and leaves mitochondria intact (1982) (57)
- Cyclosporine A inhibits mitochondrial pyridine nucleotide hydrolysis and calcium release. (1990) (57)
- Mono(ADP-ribosylation) in rat liver mitochondria. (1988) (54)
- Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown (2001) (53)
- Identification of the membrane anchor of microsomal rat liver cytochrome P-450. (1989) (52)
- Hepatic microsomal dealkylations. Inhibition by a tyrosine-copper (II) complex provided with superoxide dismutase activity. (1977) (51)
- Quantitative and mechanistic aspects of the hydroperoxide-induced release of Ca2+ from rat liver mitochondria. (1985) (50)
- No measurable increase in thymidine glycol or 8-hydroxydeoxyguanosine in liver DNA of rats treated with nafenopin or choline-devoid low-methionine diet. (1990) (48)
- Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2+ release to cyclosporine A and related compounds. (1993) (46)
- Oxidative stress, mitochondria, and apoptosis. (1998) (44)
- Lipid peroxidation decreases the rotational mobility of cytochrome P-450 in rat liver microsomes. (1985) (42)
- Mobilization of mitochondrial Ca2+ by hydroperoxy-eicosatetraenoic acid. (1987) (40)
- Phosphatidylglycerol potently protects human retinal pigment epithelial cells against apoptosis induced by A2E, a compound suspected to cause age-related macula degeneration. (2002) (40)
- Gliotoxin stimulates Ca2+ release from intact rat liver mitochondria. (1994) (40)
- Rotational diffusion of cytochrome P‐450 in rat liver microsomes (1979) (39)
- Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs. (1997) (37)
- Mitochondria, nitric oxide, and peroxynitrite. (1999) (36)
- Purification and properties of a mitochondrial NAD+ glycohydrolase. (1983) (31)
- Peroxynitrite stimulates the pyridine nucleotide-linked Ca2+ release from intact rat liver mitochondria. (1996) (31)
- Redox control of mitochondrial functions. (2001) (31)
- Cytochrome c oxidase inhibition by N-retinyl-N-retinylidene ethanolamine, a compound suspected to cause age-related macula degeneration. (2001) (29)
- Lens epithelial cell apoptosis and intracellular Ca2+ increase in the presence of xanthurenic acid (2002) (29)
- Oxidative Stress in Mitochondria (1997) (29)
- Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury (1993) (28)
- Increased fluorescence polarization of 1,6‐diphenyl‐1,3,5‐hexatriene in the phorbol myristate acetate‐stimulated plasma membrane of human neutrophils (1982) (28)
- Nitric oxide and its congeners in mitochondria: implications for apoptosis. (1998) (27)
- Mitochondrial Nitric-oxide Synthase Stimulation Causes Cytochromec Release from Isolated Mitochondria (1999) (27)
- The role of hydroperoxides as calcium release agents in rat brain mitochondria. (1984) (27)
- Direct observation of iron-induced conformational changes of mitochondrial DNA by high-resolution field-emission in-lens scanning electron microscopy. (1996) (27)
- Phenylarsine oxide stimulates pyridine nucleotide-linked Ca2+ release from rat liver mitochondria. (1994) (25)
- Photosensitization of isolated rat liver mitochondria by tetra(m-hydroxyphenyl)chlorin. (1997) (24)
- the frooxidant-induced and spontaneous mitochondrial calcium release: Inhibition by meta-iodo-benzylguanidine (mibg), a substrate for mono (adpribosylation) (1990) (24)
- Localization of the N-terminal methionine of rat liver cytochrome P-450 in the lumen of the endoplasmic reticulum. (1991) (24)
- Rotation and interaction with epoxide hydrase of cytochrome P-450 in proteoliposomes. (1991) (22)
- Rotation of Cytochrome P-450 (1982) (22)
- Decreased lipid order induced by microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in model membranes: fluorescence and electron spin resonance studies. (1985) (22)
- Nitric oxide and mitochondrial Ca2+. (1997) (22)
- Inhibition of pro-oxidant-induced mitochondrial pyridine nucleotide hydrolysis and calcium release by 4-hydroxynonenal. (1990) (21)
- 10 - Ca 2+ Movements Induced by Hydroperoxides in Mitochondria (1985) (20)
- Menadione induces a low conductance state of the mitochondrial inner membrane sensitive to bongkrekic acid. (2004) (19)
- Divicine induces calcium release from rat liver mitochondria. (1985) (19)
- Hydroperoxide effects on redox state of pyridine nucleotides and Ca2+ retention by mitochondria. (1984) (18)
- NADP+ phosphatase: a novel mitochondrial enzyme. (1987) (17)
- Inhibition by cyclosporine A of the prooxidant-induced but not of the sodium-induced calcium release from rat kidney mitochondria. (1991) (17)
- Age-related Macular Degeneration THE LIPOFUSCIN COMPONENT N-RETINYL-N-RETINYLIDENE ETHANOLAMINE DETACHES PROAPOPTOTIC PROTEINS FROM MITOCHONDRIA AND INDUCES APOPTOSIS IN MAMMALIAN RETINAL PIGMENT EPITHELIAL CELLS * (2009) (16)
- Stimulation of Ca2+ release from rat liver mitochondria by the dithiol reagent α-lipoic acid (1996) (15)
- Role of Mitochondrial DNA Modifications in Degenerative Diseases and Aging (1994) (15)
- Inhibition by superoxide dismutase of linoleic acid peroxidation induced by lipoxidase (1975) (15)
- Poly(ADP-Ribose) Biosynthesis (1987) (15)
- Prooxidant‐Induced Ca2+ Release from Liver Mitochondria (1992) (15)
- The effect of a tyrosine‐divalent copper complex on hepatic microsomal demethylation (1976) (13)
- A link between the antioxidant defense system and calcium: a proposal for the biochemical function of Bcl-2. (1995) (13)
- Effect of ebselen on Ca2+ transport in mitochondria (2000) (12)
- Control of the pyridine nucleotide-linked Ca2+ release from mitochondria by respiratory substrates. (1996) (11)
- Tyrosine · copper(II) inhibits lipid peroxidation in rat liver microsomes (1980) (11)
- Chapter 15 Mitochondrial calcium transport (1992) (10)
- Kinetics of carbon monoxide binding to phenobarbital-induced cytochrome P-450 from rat liver microsomes: a simple bimolecular process. (1985) (10)
- t-Butylhydroperoxide and gliotoxin stimulate Ca2+ release from rat skeletal muscle mitochondria. (1997) (9)
- Microsomal cytochrome P-450: substrate binding, membrane interactions, and topology. (1989) (9)
- Control of the pro-oxidant-dependent calcium release from intact liver mitochondria. (1996) (9)
- Isoelectric focusing of cytochrome P450: isolation of six phenobarbital-inducible rat liver microsomal isoenzymes. (1991) (8)
- Inhibition of the pyridine nucleotide-linked mitochondrial Ca(2+) release by 4-hydroxynonenal: the role of thiolate-disulfide conversion. (1996) (8)
- Overexpression of Bcl-2 enhances sensitivity of L929 cells to a lipophilic cationic photosensitiser (2001) (8)
- Calcium Transport and Mono(ADP-Ribosylation) in Mitochondria (1985) (7)
- Stimulation of Ca2+ release from rat liver mitochondria by the dithiol reagent alpha-lipoic acid. (1996) (6)
- Chemical modification of rat liver microsomal cytochrome P-450: study of enzymic properties and membrane topology. (1991) (6)
- Poly(ADP-Ribose): Structure, Properties and Quantification (1987) (5)
- Poly-ADP-Ribosylation in the Recovery of Mammalian Cells from DNA Damage (1987) (5)
- Poly(ADP-Ribose) Catabolism (1987) (5)
- THE LIPOFUSCIN COMPONENT N-RETINYL-N-RETINYLIDENE ETHANOLAMINE DETACHES PROAPOPTOTIC PROTEINS FROM MITOCHONDRIA AND INDUCES APOPTOSIS IN MAMMALIAN RETINAL PIGMENT EPITHELIAL CELLS* (2009) (5)
- Nuclear Acceptor Proteins for Poly(ADP-Ribose) and the Functional Consequences of Poly-ADP-Ribosylation on the Acceptor Species (1987) (4)
- Chemical modification of microsomal cytochrome P450: role of lysyl residues in hydroxylation activity (1983) (4)
- Peroxovanadate inhibits Ca2+ release from mitochondria (2002) (4)
- Insight into age-related macular degeneration: New vision in sight (2001) (4)
- MITOCHONDRIA, NO AND PEROXYNITRITE (1999) (4)
- Prooxidant-induced Ca2+ release from liver mitochondria. Specific versus nonspecific pathways. (1992) (3)
- Poly-ADP-Ribosylation and Chromatin Organization (1987) (2)
- The prooxidant-induced and spontaneous mitochondrial calcium release: inhibition by meta-iodo-benzylguanidine (MIBG), a substrate for mono (ADP-ribosylation). (1990) (2)
- Fluorescence Studies of Lipid Order in Proteoliposomes Containing Cytochrome P-490 and Its Reductase (1985) (2)
- Poly(ADP-Ribose) in Inherited Human Diseases and Experimental Disease Models (1987) (1)
- A2E INHIBITS MITOCHONDRIAL FUNCTION, CAUSES THE RELEASE OF PRO-APOPTOTIC PROTEINS AND INDUCES APOPTOSIS IN MAMMALIAN CELLS· (2001) (1)
- Poly(ADP-Ribose), Cellular Differentiation, and Gene Expression (1987) (1)
- Nitric Oxide Signaling Through Mitochondrial Calcium Release (1997) (1)
- Poly(ADP-Ribose), DNA Synthesis, and Cell Cycle Progression (1987) (1)
- Mitochondrial DNA Oxidation (1999) (0)
- DOES DIABETES MELLITUS CAUSE OXIDATIVE DAMAGE TO MITOCHONDRIAL DNA IN PANCREATIC ISLETS (1997) (0)
- Pathological apoptosis by xanthurenic acid, a tryptophan metabolite (2001) (0)
- Use of negatively charged phospholipids, as well as compositions comprising phospholipids for the treatment of the eye (2001) (0)
- R manufacture of a medicament for the treatment and / or prevention of macular degeneration (2002) (0)
- Normaloxidative damagetomitochondrial andnuclear DNA isextensive (8-hydroxydeoxyguanosine/aging/cancer/mutation) (1988) (0)
- Structure and dynamics of the liver microsomal monoxygenase system. (1988) (0)
- Reply to the comment of Dr H.I. Hadler (1989) (0)
- ATP PREVENTS HYDROPEROXIDE-INDUCED HYDROLYSIS OF PYRIDINE NUCLEOTIDES AND RELEASE OF CALCIUM IN RAT LIVER MITOCHONDRIA (1981) (0)
- NO, PEROXYNITRITE AND MITOCHONDRIAL CALCIUM (1997) (0)
- Role of mitochondria in neurodegeneration (2000) (0)
- Mono(ADP-Ribosyl)ation in Rat Liver Mitochondria (1989) (0)
- 8590 Monomolecular Complexes between Cytochrome P-450 and Its Reductase (2001) (0)
- Sarcoplasmic reticulum release channels from frog skeletal muscle display two types of calcium dependence (2001) (0)
- Introduction to serial reviews on nitric oxide in mitochondria. (2002) (0)
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Christoph Richter is affiliated with the following schools:
