Charles Russell Middaugh
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Chemistry Engineering
Charles Russell Middaugh's Degrees
- PhD Chemical Engineering Stanford University
- Masters Chemical Engineering Stanford University
- Bachelors Chemical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Charles Russell Middaugh's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality. (2009) (506)
- Nanotechnology in vaccine delivery☆ (2008) (487)
- Barriers to nonviral gene delivery. (2003) (484)
- Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins. (1992) (411)
- Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development. (2011) (391)
- Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies. (2014) (278)
- Silicone oil induced aggregation of proteins. (2005) (258)
- Biophysical characterization of PEI/DNA complexes. (2003) (251)
- Conformational Stability and Disassembly of Norwalk Virus-like Particles (2006) (231)
- Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. (2012) (216)
- Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles. (2005) (202)
- Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products. (2010) (192)
- Effects of Adsorption to Aluminum Salt Adjuvants on the Structure and Stability of Model Protein Antigens* (2005) (181)
- IpaD Localizes to the Tip of the Type III Secretion System Needle of Shigella flexneri (2006) (181)
- Nature of the interaction of heparin with acidic fibroblast growth factor. (1993) (180)
- Thermal stability of vaccines. (2003) (177)
- Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase. (1992) (160)
- Analysis of plasmid DNA from a pharmaceutical perspective. (1998) (156)
- Highly concentrated monoclonal antibody solutions: direct analysis of physical structure and thermal stability. (2007) (155)
- Nature of the interaction of growth factors with suramin. (1992) (147)
- Simultaneous monitoring of the environment of tryptophan, tyrosine, and phenylalanine residues in proteins by near-ultraviolet second-derivative spectroscopy. (1994) (144)
- Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: a bGCSF case study. (2003) (133)
- Insulin containing polyethylenimine-dextran sulfate nanoparticles. (2003) (121)
- The structure of DNA within cationic lipid/DNA complexes. (2003) (121)
- Physical stabilization of acidic fibroblast growth factor by polyanions. (1993) (120)
- High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability (2013) (111)
- Ultraviolet absorption spectroscopy. (1995) (111)
- The Potential Role of Proteoglycans in Cationic Lipid-mediated Gene Delivery (2001) (106)
- The complex inter-relationships between protein flexibility and stability. (2008) (105)
- Multidimensional methods for the formulation of biopharmaceuticals and vaccines. (2011) (105)
- Structural characterization of IgG1 mAb aggregates and particles generated under various stress conditions. (2014) (104)
- Investigation of protein/carbohydrate interactions in the dried state. 2. Diffuse reflectance FTIR studies. (2002) (101)
- Polyanions and the Proteome* (2004) (99)
- Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody. (2013) (94)
- Formulation Design of Acidic Fibroblast Growth Factor (1993) (92)
- Influence of aggregation on immunogenicity of recombinant human Factor VIII in hemophilia A mice. (2006) (90)
- Conformational origin of the aggregation of recombinant human factor VIII. (2001) (89)
- Anthrax vaccine powder formulations for nasal mucosal delivery. (2006) (88)
- Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry. (2013) (88)
- Structural stability of adenovirus type 5. (2003) (82)
- The effects of surface adsorption on the thermal stability of proteins (1992) (82)
- Compatibility, physical stability, and characterization of an IgG4 monoclonal antibody after dilution into different intravenous administration bags. (2012) (81)
- Molecular mechanism of spider silk elasticity. (1991) (80)
- Properties of synthetic spider silk fibers based on Argiope aurantia MaSp2. (2008) (79)
- Effect of pH and ionic strength on the physical stability of adenovirus type 5. (2006) (78)
- Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector. (1992) (76)
- Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations. (2007) (76)
- Determination of the apparent thermodynamic activities of saturated protein solutions. (1979) (76)
- Infrared Spectroscopic Characterization of the Interaction of Cationic Lipids with Plasmid DNA* (2001) (75)
- Formulation and characterization of DNA-polyethylenimine-dextran sulfate nanoparticles. (2003) (73)
- Solution structure of the cytoplasmic domain of phopholamban: phosphorylation leads to a local perturbation in secondary structure. (1995) (70)
- Effects of stabilizers on the destabilization of proteins upon adsorption to aluminum salt adjuvants. (2007) (70)
- Degradative covalent reactions important to protein stability (1997) (70)
- Formulation and characterization of amphotericin B-polyethylenimine-dextran sulfate nanoparticles. (2001) (67)
- Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity (2016) (67)
- Stabilization of measles virus for vaccine formulation (2008) (66)
- Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody (2015) (64)
- Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies. (2015) (62)
- Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life (2015) (61)
- The Structural Organization of Cationic Lipid-DNA Complexes* (2002) (61)
- Isothermal titration calorimetric analysis of the interaction between cationic lipids and plasmid DNA. (2001) (61)
- Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions. (2012) (61)
- Sucralfate and soluble sucrose octasulfate bind and stabilize acidic fibroblast growth factor. (1993) (60)
- Structure-Function Analysis of Invasion Plasmid Antigen C (IpaC) from Shigella flexneri * (2003) (60)
- Interaction of partially structured states of acidic fibroblast growth factor with phospholipid membranes. (1995) (59)
- Minimizing Carry-Over in an Online Pepsin Digestion System used for the H/D Exchange Mass Spectrometric Analysis of an IgG1 Monoclonal Antibody (2012) (58)
- Lyophilization and the Thermostability of Vaccines (2002) (57)
- Solution Behavior of IFN-β-1a: An Empirical Phase Diagram Based Approach (2005) (57)
- Excipients differentially influence the conformational stability and pretransition dynamics of two IgG1 monoclonal antibodies. (2012) (57)
- Stabilization of proteins by low molecular weight multi-ions. (2002) (57)
- Physical stabilization of Norwalk virus-like particles. (2008) (57)
- Analysis of the thermal and pH stability of human respiratory syncytial virus. (2005) (56)
- Comparison of high-throughput biophysical methods to identify stabilizing excipients for a model IgG2 monoclonal antibody: conformational stability and kinetic aggregation measurements. (2012) (56)
- Preparation and characterization of translocator/chaperone complexes and their component proteins from Shigella flexneri. (2007) (56)
- Effect of polyanions on the unfolding of acidic fibroblast growth factor. (1993) (55)
- Probing protein structure and dynamics by second‐derivative ultraviolet absorption analysis of cation–π interactions (2006) (54)
- A fluorescence study of the structure and accessibility of plasmid DNA condensed with cationic gene delivery vehicles. (2003) (53)
- A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine. (2006) (53)
- The adsorption of proteins to pharmaceutical container surfaces (1992) (53)
- A Formulation Development Approach to Identify and Select Stable Ultra-High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities. (2017) (52)
- A rapid, three-step process for the preformulation of a recombinant ricin toxin A-chain vaccine. (2007) (52)
- Improved data visualization techniques for analyzing macromolecule structural changes (2012) (50)
- Effects of pH and polyanions on the thermal stability of fibroblast growth factor 20. (2007) (50)
- Physical characterization and in vitro biological impact of highly aggregated antibodies separated into size-enriched populations by fluorescence-activated cell sorting. (2015) (50)
- Atypical glycosylation of an IgG monoclonal cryoimmunoglobulin. (1987) (49)
- Origin of the Isoelectric Heterogeneity of Monoclonal Immunoglobulin h1B4 (1993) (49)
- Size and conformational stability of the hepatitis A virus used to prepare VAQTA, a highly purified inactivated vaccine. (1997) (49)
- Conformational stability and differential structural analysis of LcrV, PcrV, BipD, and SipD from type III secretion systems (2007) (48)
- Partially structured self-associating states of acidic fibroblast growth factor. (1993) (48)
- Delta-sleep-inducing peptide: solution conformational studies of a membrane-permeable peptide. (1994) (48)
- Degradative covalent reactions important to protein stability. (1997) (48)
- Stability of helix-rich proteins at high concentrations. (2006) (47)
- High-throughput screening of stabilizers for Respiratory Syncytial Virus: Identification of stabilizers and their effects on the conformational thermostability of viral particles (2007) (47)
- Protein conformation and reversed-phase high-performance liquid chromatography. (1984) (47)
- A single amino acid substitution in an ectopic alpha subunit of a human carcinoma choriogonadotropin. (1986) (46)
- Ultraviolet spectroscopy as a tool in therapeutic protein development. (2011) (45)
- Native-like aggregates of factor VIII are immunogenic in von Willebrand factor deficient and hemophilia a mice. (2012) (45)
- Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles (2014) (45)
- Physical characterization of clostridium difficile toxins and toxoids: effect of the formaldehyde crosslinking on thermal stability. (2008) (44)
- Oligomeric states of the Shigella translocator protein IpaB provide structural insights into formation of the type III secretion translocon (2013) (44)
- Effect of polyanions on the refolding of human acidic fibroblast growth factor. (1991) (44)
- Differential scanning calorimetric studies of the thermal stability of plasmid DNA complexed with cationic lipids and polymers. (2002) (44)
- Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability. (2009) (43)
- Structure/function analysis of peptoid/lipitoid:DNA complexes. (2003) (43)
- Investigation of protein/carbohydrate interactions in the dried state. 1. Calorimetric studies. (2002) (43)
- Conformational Lability of Herpesvirus Protein VP22* (2000) (43)
- Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody. (2016) (42)
- Effects of solutes on empirical phase diagrams of human fibroblast growth factor 1. (2007) (42)
- Characterization of the physical stability of a lyophilized IgG1 mAb after accelerated shipping-like stress. (2015) (42)
- Preformulation studies--The next advance in aluminum adjuvant-containing vaccines. (2010) (41)
- Thermal stability of adenovirus type 2 as a function of pH. (2006) (41)
- Two-dimensional correlation spectroscopy reveals coupled immunoglobulin regions of differential flexibility that influence stability. (2007) (40)
- Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody. (2019) (40)
- A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants (2010) (39)
- An application of ultraviolet spectroscopy to study interactions in proteins solutions at high concentrations. (2012) (38)
- Preformulation studies as an essential guide to formulation development and manufacture of protein pharmaceuticals. (2002) (38)
- Effect of ionic strength and pH on the physical and chemical stability of a monoclonal antibody antigen-binding fragment. (2013) (38)
- Parenteral immunization with IpaB/IpaD protects mice against lethal pulmonary infection by Shigella. (2013) (38)
- Antigen levels and antibody titers after DNA vaccination. (2001) (37)
- Biochemical and Biophysical Comparison of Native and Chemically Synthesized Phospholamban and a Monomeric Phospholamban Analog (*) (1996) (37)
- Analysis of vaccine stability. (1996) (37)
- Compositional effects of cationic lipid/DNA delivery systems on transgene expression in cell culture. (2004) (37)
- Calculating the mass of subvisible protein particles with improved accuracy using microflow imaging data. (2015) (36)
- Effect of metal cations on the conformation and inactivation of recombinant human factor VIII. (2004) (36)
- Radar chart array analysis to visualize effects of formulation variables on IgG1 particle formation as measured by multiple analytical techniques. (2013) (35)
- Structural stability of vault particles. (2009) (35)
- High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation. (2013) (35)
- A biophysical characterization of the peptide drug pramlintide (AC137) using empirical phase diagrams. (2008) (35)
- Preformulation studies of Clostridium difficile toxoids A and B. (2008) (35)
- Examination of phenylalanine microenvironments in proteins by second-derivative absorption spectroscopy. (1991) (34)
- Role of conformational changes in the elution of proteins from reversed-phase HPLC columns. (1986) (34)
- An infrared spectroscopic study of the effect of hydration on cationic lipid/DNA complexes. (2003) (34)
- Biophysical characterization and stabilization of the recombinant albumin fusion protein sEphB4-HSA. (2012) (34)
- Effects of an extremely low frequency electromagnetic field on the cell division rate and plasma membrane of Paramecium tetraurelia. (1985) (34)
- A differential scanning calorimetric study of the bovine lens crystallins. (1989) (34)
- Physicochemical characterization of six monoclonal cryoimmunoglobulins: possible basis for cold-dependent insolubility. (1978) (33)
- Physical stability comparisons of IgG1-Fc variants: effects of N-glycosylation site occupancy and Asp/Gln residues at site Asn 297. (2014) (33)
- A simple experimental model for hydrophobic interactions in proteins. (1984) (33)
- Nonclassical transport proteins and peptides: an alternative to classical macromolecule delivery systems. (2003) (33)
- N-terminus of IpaB provides a potential anchor to the Shigella type III secretion system tip complex protein IpaD. (2013) (32)
- Structural characterization of bovine granulocyte colony stimulating factor: effect of temperature and pH. (2003) (32)
- A stopped-flow kinetic study of the assembly of nonviral gene delivery complexes. (2005) (32)
- Immunoglobulin dynamics, conformational fluctuations, and nonlinear elasticity and their effects on stability. (2008) (32)
- Bacteriophage T7 RNA polymerase and its active-site mutants. Kinetic, spectroscopic and calorimetric characterization. (1994) (32)
- The effects of substituted cyclodextrins on the colloidal and conformational stability of selected proteins. (2010) (31)
- Spectroscopic and calorimetric analyses of invasion plasmid antigen D (IpaD) from Shigella flexneri reveal the presence of two structural domains. (2006) (31)
- Presence of spectrin tetramer on the erythrocyte membrane. (1980) (31)
- Stability of lyophilized human growth hormone. (2008) (31)
- Molecular basis for the temperature-dependent insolubility of cryoglobulins--IV. Structural studies of the IgM monoclonal cryoglobulin McE. (1978) (31)
- Interaction of nucleotides with acidic fibroblast growth factor (FGF-1). (1994) (31)
- Preformulation characterization of an aluminum salt-adjuvanted trivalent recombinant protein-based vaccine candidate against Streptococcus pneumoniae. (2012) (30)
- Identification of properties important to protein aggregation using feature selection (2013) (30)
- Investigation of protein conformational stability employing a multimodal spectrometer. (2011) (30)
- Effect of polyanions on the structure and stability of repifermin (keratinocyte growth factor-2). (2007) (30)
- High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine (2017) (30)
- Production, Characterization, and Biological Evaluation of Well-Defined IgG1 Fc Glycoforms as a Model System for Biosimilarity Analysis. (2016) (29)
- The characterization, stabilization, and formulation of acidic fibroblast growth factor. (1996) (29)
- Conformational lability of two molecular chaperones Hsc70 and gp96: effects of pH and temperature. (2006) (29)
- Temperature dependent 2nd derivative absorbance spectroscopy of aromatic amino acids as a probe of protein dynamics (2009) (29)
- Effect of solutes on the cold-induced insolubility of monoclonal cryoimmunoglobulins. (1977) (28)
- Stability of the Clostridium botulinum type A neurotoxin complex: an empirical phase diagram based approach. (2007) (27)
- Hyaluronic acid nanoparticles titrate the viscoelastic properties of viscosupplements. (2013) (27)
- An empirical phase diagram approach to investigate conformational stability of “second‐generation” functional mutants of acidic fibroblast growth factor‐1 (2012) (26)
- Biophysical characterization and conformational stability of Ebola and Marburg virus-like particles. (2011) (26)
- Near-infrared photoacoustic spectroscopy of proteins. (1984) (26)
- Biophysical characterization of Chlamydia trachomatis CT584 supports its potential role as a type III secretion needle tip protein. (2009) (26)
- Noncovalent PEGylation by polyanion complexation as a means to stabilize keratinocyte growth factor-2 (KGF-2). (2011) (26)
- An Empirical Phase Diagram–High‐Throughput Screening Approach to the Characterization and Formulation of Biopharmaceuticals (2010) (26)
- Circular dichroism of peptides. (2014) (26)
- H1N1 influenza virus-like particles: physical degradation pathways and identification of stabilizers. (2011) (26)
- A Micro-Polyethylene Glycol Precipitation Assay as a Relative Solubility Screening Tool for Monoclonal Antibody Design and Formulation Development. (2016) (25)
- The Inhibitory Action of Phospholamban Involves Stabilization of α-Helices within the Ca-ATPase† (2002) (25)
- A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays* (2007) (25)
- Characterization of the interaction of single tryptophan containing mutants of IpaC from Shigella flexneri with phospholipid membranes. (2006) (25)
- Analysis of cationic-lipid-plasmid-DNA complexes. (2007) (24)
- High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin (2017) (24)
- An improved methodology for multidimensional high-throughput preformulation characterization of protein conformational stability. (2012) (24)
- Correlating the Impact of Well-Defined Oligosaccharide Structures on Physical Stability Profiles of IgG1-Fc Glycoforms. (2016) (24)
- Evaluation of the physical stability of the EC5 domain of E-cadherin: effects of pH, temperature, ionic strength, and disulfide bonds. (2009) (24)
- Detection of proteins and phenol in DNA samples with second-derivative absorption spectroscopy. (1992) (24)
- Analysis of protein association by partitioning in aqueous two-phase polymer systems: applications to the tetramer-dimer dissociation of hemoglobin. (1980) (24)
- Towards development of stable formulations of a live attenuated bacterial vaccine: A preformulation study facilitated by a biophysical approach (2009) (24)
- Physical characterization of MxiH and PrgI, the needle component of the type III secretion apparatus from Shigella and Salmonella (2006) (24)
- Biophysical characterization of polymeric and liposomal gene delivery systems using empirical phase diagrams. (2006) (23)
- Solution behavior of IFN-beta-1a: an empirical phase diagram based approach. (2005) (23)
- Development of a stable virus-like particle vaccine formulation against Chikungunya virus and investigation of the effects of polyanions. (2013) (23)
- High throughput prediction of the long-term stability of pharmaceutical macromolecules from short-term multi-instrument spectroscopic data. (2014) (23)
- Biophysical and stabilization studies of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein. (2009) (23)
- Comparison of proteins from thermophilic and nonthermophilic sources in terms of structural parameters inferred from amino acid composition. (2009) (23)
- Thermodynamic analysis of binding and protonation in DOTAP/DOPE (1:1): DNA complexes using isothermal titration calorimetry. (2003) (23)
- Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants. (2015) (23)
- Investigations of the molecular basis for the temperature-dependent insolubility of cryoglobulins. II. Spectroscopic studies of the IgM monoclonal cryoglobulin McE. (1977) (22)
- The solubility of bovine lens crystallins. (1981) (22)
- Reorientation Motion and Preferential Interactions of a Peptide in Denaturants and Osmolyte. (2016) (22)
- Physical characterization and formulation development of a recombinant pneumolysoid protein-based pneumococcal vaccine. (2013) (22)
- Correlating the Effects of Antimicrobial Preservatives on Conformational Stability, Aggregation Propensity, and Backbone Flexibility of an IgG1 mAb. (2017) (22)
- Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII). (2005) (22)
- Electrostatic changes in phosphorylase kinase induced by its obligatory allosteric activator Ca2+ (2007) (22)
- Local dynamics and their alteration by excipients modulate the global conformational stability of an lgG1 monoclonal antibody. (2012) (21)
- Structural stability of hepatitis C virus envelope glycoprotein E1: effect of pH and dissociative detergents. (2009) (21)
- The interaction of heparin/polyanions with bovine, porcine, and human growth hormone. (2008) (21)
- Aggregation kinetics of recombinant human FVIII (rFVIII). (2005) (21)
- pH sensitivity of type III secretion system tip proteins (2008) (21)
- The temperature-dependent stoichiometry of mixed cryoimmunoglobulins. (1986) (21)
- Thermodynamic basis for the abnormal solubility of monoclonal cryoimmunoglobulins. (1980) (20)
- Conformational flexibility, hydration and state parameter fluctuations of fibroblast growth factor-10: effects of ligand binding. (2006) (20)
- Characterization and Protective Efficacy of Type III Secretion Proteins as a Broadly Protective Subunit Vaccine against Salmonella enterica Serotypes (2018) (20)
- Fourier transform infrared spectroscopy of peptides. (2014) (20)
- Vaccines as physically and chemically well-defined pharmaceutical dosage forms (2010) (20)
- Inhibition of alpha-crystallin aggregation by gamma-crystallin. (1990) (19)
- Linking the solution viscosity of an IgG2 monoclonal antibody to its structure as a function of pH and temperature. (2013) (19)
- Monoclonal cryoglobulinemia with macroglobulinemia in a dog. (1977) (19)
- Understanding the relevance of local conformational stability and dynamics to the aggregation propensity of an IgG1 and IgG2 monoclonal antibodies (2013) (19)
- Complex effects of molecular chaperones on the aggregation and refolding of fibroblast growth factor-1. (2001) (19)
- Determining the Identity and Purity of Recombinant Proteins by UV Absorption Spectroscopy (1995) (19)
- Mechanistic aspects of chiral discrimination by surface-immobilized ?1-acid glycoprotein (1999) (19)
- Spa47 is an oligomerization‐activated type three secretion system (T3SS) ATPase from Shigella flexneri (2016) (19)
- Electrostatic properties of cryoimmunoglobulins. (1988) (19)
- Comparison of the structural stability and dynamic properties of recombinant anthrax protective antigen and its 2-fluorohistidine-labeled analogue. (2012) (19)
- Evolution and design of protein structure by folding nucleus symmetric expansion. (2014) (18)
- Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody. (2017) (18)
- Formulation development of a plant-derived h1n1 influenza vaccine containing purified recombinant hemagglutinin antigen (2012) (18)
- Role of bound water in biological membrane structure: fluorescence and infrared studies. (1979) (18)
- Parathyroid hormone is a heparin/polyanion binding protein: Binding energetics and structure modification (2007) (18)
- A photochemical crosslinking study of the subunit structure of membrane-associated spectrin. (1980) (18)
- Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis (2013) (17)
- Stabilization of proteins by recombinant human gelatins. (2007) (17)
- Impact of Detergent on Biophysical Properties and Immune Response of the IpaDB Fusion Protein, a Candidate Subunit Vaccine against Shigella Species (2014) (16)
- Quantitative analysis of protein mixtures by second derivative absorption spectroscopy. (1989) (16)
- Formulation and immunogenicity of a potential multivalent type III secretion system-based protein vaccine. (2010) (16)
- Preformulation study of highly purified inactivated polio vaccine, serotype 3. (2014) (16)
- Potential use of non-classical pathways for the transport of macromolecular drugs (2000) (16)
- Hv(1), a variable-region genetic marker of human immunoglobulin heavy chains. (1978) (16)
- Comparative signature diagrams to evaluate biophysical data for differences in protein structure across various formulations. (2013) (15)
- The physical stability of the recombinant tuberculosis fusion antigens h1 and h56. (2013) (15)
- A single aromatic core mutation converts a designed “primitive” protein from halophile to mesophile folding (2015) (15)
- Comparative spectroscopic studies of four crotoxin homologs and their subunits. (1989) (15)
- Kinetics of the precipitation of cryoimmunoglobulins. (1987) (15)
- Development of a candidate stabilizing formulation for bulk storage of a double mutant heat labile toxin (dmLT) protein based adjuvant (2017) (14)
- Does random collisional cross-linking occur? (1980) (14)
- Fine-Specificity Epitope Analysis Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies (2018) (14)
- The Atypical Response Regulator Protein ChxR Has Structural Characteristics and Dimer Interface Interactions That Are Unique within the OmpR/PhoB Subfamily* (2011) (14)
- Case Studies Applying Biophysical Techniques to Better Characterize Protein Aggregates and Particulates of Varying Size (2013) (14)
- The response of type three secretion system needle proteins MxiHΔ5, BsaLΔ5, and PrgIΔ5 to temperature and pH (2008) (14)
- Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study. (2016) (14)
- Probing structurally altered and aggregated states of therapeutically relevant proteins using GroEL coupled to bio‐layer interferometry (2014) (14)
- Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. (2016) (14)
- Characterization of an oncolytic herpes simplex virus drug candidate. (2015) (14)
- Spectroscopic methods for the physical characterization and formulation of nonviral gene delivery systems. (2008) (14)
- Effect of D2O on the temperature‐dependent solubility of cryoglobulin and noncryoglobulin IgM (1977) (13)
- Label-Free, Direct Measurement of Protein Concentrations in Turbid Solutions with a UV-Visible Integrating Cavity Absorbance Spectrometer. (2018) (13)
- Enhancements in gene expression by the choice of plasmid DNA formulations containing neutral polymeric excipients. (2002) (13)
- Mechanism of a decrease in potency for the recombinant influenza A virus hemagglutinin H3 antigen during storage. (2014) (13)
- Deamidation of polyanion-stabilized acidic fibroblast growth factor. (1995) (13)
- Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes. (2007) (13)
- Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies (2017) (13)
- Impact of Glycosylation on the Local Backbone Flexibility of Well-Defined IgG1-Fc Glycoforms Using Hydrogen Exchange-Mass Spectrometry. (2018) (12)
- Conformational stability of Cu,Zn-superoxide dismutase, the apoprotein, and its zinc-substituted derivatives: second-derivative spectroscopy of phenylalanine and tyrosine residues. (1991) (12)
- Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements. (2017) (12)
- Use of a folding model and in situ spectroscopic techniques for rational formulation development and stability testing of monoclonal antibody therapeutics. (2010) (12)
- Using spectroscopic and microscopic methods to probe the structural stability of human adenovirus type 4 (2010) (12)
- Fundamental Structures and Behaviors of Proteins (2010) (12)
- Epitope-labeled Soluble Human Interleukin-5 (IL-5) Receptors (1995) (12)
- The role of covalent dimerization on the physical and chemical stability of the EC1 domain of human E-cadherin. (2009) (12)
- Characterization of the Changes in Secondary Structure and Architecture of Elastin−Mimetic Triblock Polypeptides during Thermal Gelation (2006) (12)
- Adsorption of recombinant poxvirus L1-protein to aluminum hydroxide/CpG vaccine adjuvants enhances immune responses and protection of mice from vaccinia virus challenge. (2013) (12)
- A Network-based Analysis of Polyanion-binding Proteins Utilizing Yeast Protein Arrays*S (2006) (12)
- Applications of Ultraviolet Absorption Spectroscopy to the Analysis of Biopharmaceuticals (1997) (12)
- The structure, stability, and complex behavior of recombinant human gelatins. (2007) (12)
- Biosimilarity Assessments of Model IgG1-Fc Glycoforms Using a Machine Learning Approach. (2016) (12)
- The Botanical Drug Substance Crofelemer as a Model System for Comparative Characterization of Complex Mixture Drugs. (2017) (11)
- Detailed microscopic unfolding pathways of an α-helix and a β-hairpin: direct observation and molecular dynamics. (2014) (11)
- Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen (2013) (11)
- The Rationale for Targeting the NAD/NADH Cofactor Binding Site of Parasitic S-Adenosyl-L-Homocysteine Hydrolase for the Design of Anti-Parasitic Drugs (2009) (11)
- Advances in vaccines against neglected tropical diseases (2012) (11)
- A transforming growth factor-alpha-Pseudomonas exotoxin hybrid protein undergoes pH-dependent conformational changes conducive to membrane interaction. (1993) (11)
- Characterization and stabilization of recombinant human protein pentraxin (rhPTX-2). (2013) (11)
- Identifying stabilizers of plasmid DNA for pharmaceutical use. (2011) (10)
- Aggregation state of the gonadotropin receptor. (1985) (10)
- Structural Characterization and Physicochemical Stability Profile of a Double Mutant Heat Labile Toxin Protein Based Adjuvant (2017) (10)
- High-Throughput Biophysical Approaches to Therapeutic Protein Development (2013) (10)
- Probing the affinity of polyanions for acidic fibroblast growth factor by unfolding kinetics. (1994) (10)
- Investigations of the molecular basis for the temperature-dependent insolubility of cryoglobulins. VI. Quenching by acrylamide of the intrinsic tryptophan fluorescence of cryoglobulin and non-cryoglobulin IgM proteins. (1978) (10)
- BIOPHYSICAL APPROACHES TO THE PHARMACEUTICAL DEVELOPMENT OF PROTEINS (1990) (10)
- Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1. (2019) (10)
- Non-exponential kinetics and a complete folding pathway of an α-helical heteropeptide: direct observation and comprehensive molecular dynamics. (2014) (10)
- Soluble Antigen Arrays for Selective Desensitization of Insulin-Reactive B Cells. (2019) (10)
- Developing Biologics Tablets: The Effects of Compression on the Structure and Stability of Bovine Serum Albumin and Lysozyme. (2019) (10)
- Secondary structure of a dynamic type I’β-hairpin peptide (2004) (10)
- Novel Ricin Subunit Antigens With Enhanced Capacity to Elicit Toxin-Neutralizing Antibody Responses in Mice. (2016) (10)
- Formulation and immunogenicity studies of type III secretion system needle antigens as vaccine candidates. (2010) (9)
- Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability. (2008) (9)
- Deamidation of model β-turn cyclic peptides in the solid state (2005) (9)
- DNA complexed with TAT peptide and condensed using calcium possesses unique structural features compared to PEI polyplexes. (2014) (9)
- A Collection of Single-Domain Antibodies that Crowd Ricin Toxin’s Active Site (2018) (9)
- Biophysical characterization of the type III secretion tip proteins and the tip proteins attached to bacterium-like particles. (2015) (9)
- The interaction of γ-crystallins with model surfaces (1991) (9)
- Evaluation of lumazine synthase from Bacillus anthracis as a presentation platform for polyvalent antigen display (2017) (9)
- Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. (2012) (9)
- Stabilization of the FK506 binding protein by ligand binding. (1991) (9)
- Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody-containing formulation. (2019) (9)
- Spectroscopic analysis of highly concentrated suspensions of bovine somatotropin in sesame oil. (2005) (9)
- Evidence for an equilibrium intermediate in the folding-unfolding pathway of a transforming growth factor-alpha-Pseudomonas exotoxin hybrid protein. (1994) (9)
- Effect of 2 Emulsion-Based Adjuvants on the Structure and Thermal Stability of Staphylococcus aureus Alpha-Toxin. (2018) (8)
- Biophysical Signatures of Monoclonal Antibodies (2010) (8)
- Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine (2013) (8)
- Measuring protein spectra in the presence of light scattering. (1993) (8)
- Polyphasic linkage between protein solubility and ligand binding in the hemoglobin-polyethylene glycol system. (1980) (8)
- Analytical and biological characterization of supercoiled plasmids purified by various chromatographic techniques. (2005) (8)
- Effect of Phosphate Ion on the Structure of Lumazine Synthase, an Antigen Presentation System From Bacillus anthracis. (2017) (8)
- Prediction Machines: Applied Machine Learning for Therapeutic Protein Design and Development. (2020) (8)
- Chemical crosslinking of cell membranes (2004) (8)
- Ultraviolet absorption spectroscopy of peptides. (2014) (8)
- Studies of the conformational stability of invasion plasmid antigen B from Shigella (2013) (8)
- SOLUTION STRUCTURE OF THE CYTOPLASMIC DOMAIN OF PHOSPHOLAMBAN (1995) (8)
- A calorimetric examination of the effect of myotoxin a on the thermotropic phase behavior of model lipid membranes. (1987) (8)
- Challenges and opportunities of using liquid chromatography and mass spectrometry methods to develop complex vaccine antigens as pharmaceutical dosage forms. (2016) (8)
- Biomedical Applications of Lumazine Synthase. (2018) (8)
- Localization of a conformational anomaly to the Fabmu region of a monoclonal IgM cryoglobulin. (1978) (7)
- Spectroscopic characterization of tick anticoagulant peptide. (1995) (7)
- Separation and analysis of peptides and proteins. (1999) (7)
- DB-PABP: a database of polyanion-binding proteins (2007) (7)
- pH-Dependent Phase Behavior and Stability of Cationic Lipid-mRNA Nanoparticles. (2021) (7)
- Stabilization and Formulation of Vaccines (2014) (7)
- Biophysical Characterization of the Type III Secretion System Translocator Proteins and the Translocator Proteins Attached to Bacterium-Like Particles. (2015) (7)
- Optimization of RG1-VLP vaccine performance in mice with novel TLR4 agonists. (2020) (7)
- Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2. (2019) (6)
- Recent advances in our understanding of protein conformational stability from a pharmaceutical perspective. (1998) (6)
- Chemical Stability of the Botanical Drug Substance Crofelemer: A Model System for Comparative Characterization of Complex Mixture Drugs. (2017) (6)
- Effect of iron oxide nanoparticles on the oxidation and secondary structure of growth hormone. (2019) (6)
- The effect of temperature on ribose-5-phosphate isomerase from a mesophile, Thiobacillus thioparus, and a thermophile, Bacillus caldolyticus. (1976) (6)
- Self-Assembled Coacervates of Chitosan and an Insect Cuticle Protein Containing a Rebers-Riddiford Motif. (2018) (6)
- Biophysical characterization of rotavirus serotypes G1, G3, and G4 (2010) (6)
- The inhibitory action of phospholamban involves stabilization of alpha-helices within the Ca-ATPase. (2002) (6)
- Influence of the valine zipper region on the structure and aggregation of the basic leucine zipper (bZIP) domain of activating transcription factor 5 (ATF5). (2012) (5)
- Size exclusion HPLC method for the determination of acidic fibroblast growth factor in viscous formulations. (1997) (5)
- Comparative Characterization of Crofelemer Samples Using Data Mining and Machine Learning Approaches With Analytical Stability Data Sets. (2017) (5)
- Spectroscopic characterization of textilotoxin, a presynaptic neurotoxin from the venom of the Australian eastern brown snake (Pseudonaja t. textilis). (1989) (5)
- A formulation method to improve the physical stability of macromolecular-based drug products (2012) (5)
- The Use of a GroEL-BLI Biosensor to Rapidly Assess Preaggregate Populations for Antibody Solutions Exhibiting Different Stability Profiles. (2018) (5)
- Effects of glycan structure on the stability and receptor binding of an IgG4-Fc. (2019) (5)
- [97] Bacterial ribosephosphate isomerase (1982) (5)
- Vaccine Delivery: Current Routes of Administration and Novel Approaches (2016) (5)
- Probing Selection Mechanism of the Most Favorable Conformation of a Dipeptide in Chaotropic and Kosmotropic Solution. (2016) (5)
- Thermodynamics of monoclonal and mixed cryoimmunoglobin solubilization. (1987) (4)
- Improved Comparative Signature Diagrams to Evaluate Similarity of Storage Stability Profiles of Different IgG1 mAbs. (2016) (4)
- The interaction of cryoimmunoglobulins with a model surface. (1991) (4)
- Amino/Amido Conjugates Form to Nanoscale Cobalt Physiometacomposite (PMC) Materials Functionally Delivering Nucleic Acid Therapeutic to Nucleus Enhancing Anticancer Activity via Ras-Targeted Protein Interference. (2020) (4)
- Structural Characterization and Formulation Development of a Trivalent Equine Encephalitis Virus-Like Particle Vaccine Candidate. (2018) (4)
- Fluorescence spectroscopy of peptides. (2014) (4)
- Evaluation of NAD(H) Analogues as Selective Inhibitors for Trypanosoma Cruzi S-Adenosylhomocysteine Hydrolase (2009) (4)
- Preformulation Characterization, Stabilization, and Formulation Design for the Acrylodan-Labeled Glucose-Binding Protein SM4-AC. (2017) (4)
- Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus (2020) (4)
- The analysis of protein pharmaceuticals: Near future advances (2004) (4)
- The effect of interchain disulfide bond cleavage on the cold induced precipitation of cryoimmunoglobulins. (1986) (4)
- The cytoplasmic portion of the T3SS inner membrane ring components sort into distinct families based on biophysical properties. (2019) (4)
- In Silico Classification of Proteins from Acidic and Neutral Cytoplasms (2012) (4)
- Spectroscopy of Vaccines (2011) (4)
- Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2 (2021) (4)
- Molecular basis for the temperature-dependent insolubility of cryoglobulins--IX. Physicochemical characterization of an IgG1, kappa monoclonal cryoimmunoglobulin exhibiting marginal low temperature-dependent insolubility. (1980) (4)
- Origin of the Photosensitivity of a Monoclonal Immunoglobulin G. (2010) (3)
- Production of Well-Characterized Virus-like Particles in an Escherichia coli-Based Expression Platform for Preclinical Vaccine Assessments. (2016) (3)
- High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Non-Neutralizing Single Domain Antibodies on Ricin Toxin's Enzymatic and Binding Subunits (2017) (3)
- Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. Role of lysyl and tyrosyl residues of the C-terminal extension. (2010) (3)
- Structure of synthetic peptide analogues of an eggshell protein of Schistosoma mansoni (1993) (3)
- The Physical Analysis of Vaccines (2015) (3)
- Raman spectra and conformational structures of Fabμ and (Fc)5 μ fragments of cryoglobulin IgM-κ McE (1979) (3)
- Changes in structure of alpha 2-macroglobulin upon reaction with trypsin as assessed by light scattering and differential scanning calorimetry. (1993) (2)
- Probing Shear Thinning Behaviors of IgG Molecules at the Air-Water Interface via Rheological Methods. (2016) (2)
- Investigating the dynamics and polyanion binding sites of fibroblast growth factor‐1 using hydrogen‐deuterium exchange mass spectrometry (2018) (2)
- Correction to Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements. (2017) (2)
- Molecular basis for the temperature-dependent insolubility of cryoglobulins. XII. Anomalous mobility of monoclonal cryoimmunoglobulin heavy chains accompanying polyacrylamide gel electrophoresis in sodium dodecyl sulfate. (1981) (2)
- Novel lipid A mimetics, BECC438 and BECC470, act as potent adjuvants in bacterial and viral subunit vaccines (2020) (2)
- High Throughput Screening for Stabilizers of Vaccine Antigens (2013) (2)
- Formulation and delivery of biopharmaceuticals. (1996) (2)
- KINETIC BEHAVIOR OF A THERMOPHILIC ENZYME IN RESPONSE TO TEMPERATURE PERTURBATIONS (1976) (2)
- Native-like aggregates of Factor VIII (FVIII) are immunogenic von Willebrand Factor deficient and hemophilia A mice (2013) (2)
- Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity (2018) (2)
- Preformulation Characterization and the Effect of Ionic Excipients on the Stability of a Novel DB Fusion Protein (2020) (2)
- Synthetic Cationic Autoantigen Mimics Glatiramer Acetate Persistence at the Site of Injection and Is Efficacious Against Experimental Autoimmune Encephalomyelitis (2021) (2)
- An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. (2016) (2)
- Biophysical characterization and formulation of TP40: A chimeric protein that requires a pH-dependent conformational change for its biological activity. (1996) (2)
- Studies of the aggregation of RNase Sa. (2014) (1)
- Deamidation of model beta-turn cyclic peptides in the solid state. (2005) (1)
- Infrared spectroscopy. (1995) (1)
- Observing reorientation dynamics with Time-Resolved fluorescence and molecular dynamics in varying periodic boundary conditions (2021) (1)
- Proteins as Drugs: Analysis, Formulation and Delivery (1999) (1)
- Bacterial ribosephosphate isomerase. (1982) (1)
- Expediting Early Preformulation Studies (2012) (1)
- The interaction of gamma-crystallins with model surfaces. (1991) (1)
- Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. (2018) (1)
- Dissecting Multiple Pathways in the Relaxation Dynamics of Helix <==> Coil Transitions with Optimum Dimensionality Reduction (2021) (1)
- Probing the Internal Dynamics and Shape of Simple Peptides in Urea, Guanidinium Hydrochloride, and Proline Solutions with Time-Resolved Fluorescence Anisotropy and Atomistic Cosolvent Simulations. (2021) (1)
- Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to Photo-degradation of N-Acetyl-l-tryptophan Amide. (2021) (1)
- Formulation Studies During Preclinical Development of Influenza Hemagglutinin and Virus-Like Particle Vaccine Candidates. (2016) (1)
- Molten Globule-Lipid Bilayer Interactions and Their Implications for Protein Transport and Aggregation (2006) (1)
- Microsoft Word-yeast-4-10-06_BIND_Miller_fang_Seidel_Yassen#10_network-fo.. (2006) (0)
- Chapter 8: Biophysical Characterization and the Development of Therapeutic Proteins (2020) (0)
- CHAPTER 1 Fundamental Structures and Behaviors of Proteins (2010) (0)
- Intra-micellar and extra-micellar oxidation in phosphate and histidine buffers containing polysorbate 80. (2022) (0)
- BIOTECHNOLOGY Structural Stability of Vault Particles (2009) (0)
- Polycationic Peptides and Proteins in Drug Delivery: Focus on Nonclassical Transport (2005) (0)
- Publisher's Note: "Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study" [J. Chem. Phys. 144, 245103 (2016)]. (2016) (0)
- Chapter 7: An Empirical Phase Diagram: High-Throughput Screening Approach to the Characterization and Formulation of Biopharmaceuticals (2020) (0)
- Raman spectra and conformational structures of Fab mu and (Fc)5 mu fragments of cryoglobulin IgM-kappa McE. (1979) (0)
- Correlating the Impact of Well-Defined Oligosaccharide Structures on Physical Stability Profiles and Local Flexibility of IgG 1-Fc Glycoforms (2017) (0)
- Secondary structure characteristics of proenkephalin peptides E, B, and F (1990) (0)
- 2.1A resolution structure of the ChxR receiver domain containing I3C from Chlamydia trachomatis (2011) (0)
- Evidence for an equilibrium intermediate in the folding-unfolding pathway of a transforming growth factor-.alpha.-Pseudomonas exotoxin hybrid protein. [Erratum to document cited in CA120:156995] (1994) (0)
- Is the Tyrosine Rich Eggshell Protein of Schistosoma Mansoni an Electron Transport Chain (1992) (0)
- Overcoming formulation challenges for the next generation of vaccines (2016) (0)
- Tissue-directed gene delivery systems (2020) (0)
- Prediction of Polyanion Binding Potential in Proteins Using Random Forest (2007) (0)
- 561. Analytical Characterization of Supercoiled Plasmids|[ast]| (2005) (0)
- Title Conformational Lability of Herpes Virus Protein VP 22 Authors (2000) (0)
- The Thermal Stabilization of Vaccines Against Agents of Bioterrorism (2005) (0)
- PHASE DIAGRAMS and MACROMOLECULAR STABILITY (2006) (0)
- Entropic DNA. (1985) (0)
- Khasa H, Kramer R, Maddux N, Hamborg M, Joshi SB, Volkin DB, Middaugh, CR. 2013. Studies of the Aggregation of RNase Sa. J Pharm Sci 103:395-399. (2014) (0)
- Dielectric Behavior or Biological Molecules in Solution (Grant, E. H.; Sheppard R. J.; South G. P.) (1979) (0)
- High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability (2013) (0)
- Conformational Changes and Drivers of Monoclonal Antibody Liquid-Liquid Phase Separation. (2022) (0)
- Physical stability and mixed domain binding properties of the EC5 domain of e-cadherin (2006) (0)
- Effect of Two Emulsion-Based Adjuvants on the Structure and Thermal Stability of S. aureus Alpha-toxin (2018) (0)
- Characterization of the Shigella flexneri Type Three Secretion System (T3SS) ATPase Spa47 (2015) (0)
- Cooperative Equilibria in Physical Biochemistry. Monographs on Physical Biochemistry (Poland, D.) (1980) (0)
- Subunit-based vaccines (2022) (0)
- Low resolution structural determination of lipoprotein6.6: a membrane component of Borrelia burgdorferi (753.2) (2014) (0)
- Thermally gelling , thermally responsive elastin-mimetic triblock hydrogels (2004) (0)
- The structural basis of histone modifying enzyme specificity and promiscuity: Implications for metabolic regulation and drug design. (2022) (0)
- Impact of Detergent on the Biophysical Properties and Immune Response of the IpaDB Fusion Protein , a Candidate Subunit Vaccine against Shigella spp . (2018) (0)
- Secondary structure of a dynamic type I'beta-hairpin peptide. (2004) (0)
- 2.15A resolution structure (I41 Form) of the ChxR receiver domain from Chlamydia trachomatis (2011) (0)
- Phenol Oxidase Mediated Protein Cross-Linking (1989) (0)
- Unique within the OmpR/PhoB Subfamily Dimer Interface Interactions That Are ChxR Has Structural Characteristics and The Atypical Response Regulator Protein Protein Structure and Folding: (2013) (0)
- 1.6A resolution structure of the ChxR receiver domain from Chlamydia trachomatis (2011) (0)
- Identification of properties important to protein aggregation using feature selection (2013) (0)
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