Charles S. Lieber
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Chemistry
Charles S. Lieber's Degrees
- PhD Chemistry Stanford University
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(Suggest an Edit or Addition)Charles S. Lieber's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. (1990) (1174)
- Cytochrome P-4502E1: its physiological and pathological role. (1997) (879)
- Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo. (1970) (755)
- The feeding of alcohol in liquid diets: two decades of applications and 1982 update. (1982) (683)
- Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. (2004) (624)
- Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet. (1967) (539)
- EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS. (1965) (533)
- Ethanol Oxidation by Hepatic Microsomes: Adaptive Increase after Ethanol Feeding (1968) (515)
- Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. (1989) (500)
- High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects. (1975) (493)
- Alcohol and the liver: 1994 update. (1994) (483)
- Gender differences in pharmacokinetics of alcohol. (2001) (469)
- Liquid diet technique of ethanol administration: 1989 update. (1989) (438)
- Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review. (1999) (435)
- Medical disorders of alcoholism. (1995) (431)
- Ethanol metabolism, cirrhosis and alcoholism. (1997) (429)
- Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. (1988) (427)
- Model of nonalcoholic steatohepatitis. (2004) (411)
- The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro. (1961) (365)
- Effects of ethanol on lipid metabolism. (1979) (349)
- Effect of alcohol (ethanol) administration on sex-hormone metabolism in normal men. (1976) (335)
- Hepatic Microsomal Enzymes in Man and Rat: Induction and Inhibition by Ethanol (1968) (328)
- Alcohol and the Liver (1992) (325)
- Alcohol-induced hepatic injury in nonalcoholic volunteers. (1968) (321)
- Relationships Between Nutrition, Alcohol Use, and Liver Disease (2003) (319)
- High blood alcohol levels in women. (2010) (318)
- Hepatic vitamin A depletion in alcoholic liver injury. (1982) (315)
- Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid. (1985) (309)
- S‐Adenosyl‐L‐methionine attenuates alcohol‐induced liver injury in the baboon (1990) (309)
- The intralobular distribution of ethanol‐inducible P450IIE1 in rat and human liver (1989) (304)
- Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. (1984) (301)
- Role of oxidative stress and antioxidant therapy in alcoholic and nonalcoholic liver diseases. (1997) (301)
- Pathogenesis of alcohol-induced accumulation of protein in the liver. (1977) (292)
- The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo. (1972) (290)
- Hepatic, metabolic and toxic effects of ethanol: 1991 update. (1991) (289)
- The ultrastructure of fatty liver induced by prolonged ethanol ingestion. (1966) (289)
- Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon. (1994) (286)
- ALCOHOL: its metabolism and interaction with nutrients. (2000) (286)
- Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. (1991) (280)
- Quantitative relationship between amount of dietary fat and severity of alcoholic fatty liver. (1970) (275)
- Interrelation of uric acid and ethanol metabolism in man. (1962) (275)
- Experimental methods of ethanol administration (1989) (269)
- Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. (1984) (263)
- Acetaldehyde selectively stimulates collagen production in cultured rat liver fat‐storing cells but not in hepatocytes (1990) (251)
- Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats. (1971) (246)
- Reconstitution of the microsomal ethanol-oxidizing system. Qualitative and quantitative changes of cytochrome P-450 after chronic ethanol consumption. (1977) (239)
- Alcoholic liver disease: new insights in pathogenesis lead to new treatments. (2000) (239)
- The Discovery of the Microsomal Ethanol Oxidizing System and Its Physiologic and Pathologic Role (2004) (238)
- Perivenular fibrosis in alcoholic liver injury: ultrastructure and histologic progression. (1982) (238)
- Ethanol Increases Hepatic Smooth Endoplasmic Reticulum and Drug-Metabolizing Enzymes (1968) (237)
- Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. (1999) (237)
- The feeding of ethanol in liquid diets. (1986) (235)
- Alcoholic hepatomegaly: accumulation of protein in the liver (1975) (234)
- Induction of cytochrome P‐4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA (1993) (229)
- Some metabolic effects of ethyl alcohol. (1962) (224)
- Histogenesis of alcoholic fibrosis and cirrhosis in the baboon. (1980) (211)
- Effects of fasting and chronic alcohol consumption on the first-pass metabolism of ethanol. (1987) (207)
- Alcohol-related diseases and carcinogenesis. (1979) (207)
- Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates. (1974) (204)
- Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism. (1970) (202)
- Effects of chronic ethanol treatment of mitochondrial functions damage to coupling site I. (1974) (196)
- Ultrastructural alterations in human hepatocytes following ingestion of ethanol with adequate diets. (1966) (194)
- Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat‐storing cells through a protein synthesis–dependent mechanism (1991) (189)
- Role of dietary, adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. (1966) (189)
- Lipid peroxidation and antioxidant defense systems in rat liver after chronic ethanol feeding (1989) (189)
- Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets. (1975) (187)
- The energy cost of the metabolism of drugs, including ethanol. (1972) (185)
- Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. (1990) (183)
- First pass metabolism of ethanol--a gastrointestinal barrier against the systemic toxicity of ethanol. (1985) (179)
- [58] Animal models of chronic ethanol toxicity (1994) (176)
- Lipocytes and transitional cells in alcoholic liver disease: A morphometric study (1988) (174)
- Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase. (2002) (174)
- Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. (1989) (174)
- Efcts of chronic ethanol feeding on serum lipoprotein metabolism in the rat. (1970) (173)
- Perspectives: do alcohol calories count? (1991) (167)
- Alcoholic fatty liver in man on a high protein and low fat diet. (1968) (167)
- Perivenular fibrosis as precursor lesion of cirrhosis. (1985) (167)
- Biochemical factors in alcoholic liver disease. (1993) (166)
- Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats. (1986) (166)
- Hepatic Fibrosis After Long‐Term Administration of Ethanol and Moderate Vitamin A Supplementation in the Rat (2007) (165)
- Hepatic vitamin A depletion after chronic ethanol consumption in baboons and rats. (1981) (165)
- Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man. (1968) (165)
- Effects of ethanol on liver microtubules and Golgi apparatus. Possible role in altered hepatic secretion of plasma proteins. (1979) (164)
- Effects of cimetidine on gastric alcohol dehydrogenase activity and blood ethanol levels. (1989) (163)
- Mechanism of ethanol induced hepatic injury. (1990) (161)
- Leptin Stimulates Tissue Inhibitor of Metalloproteinase-1 in Human Hepatic Stellate Cells (2004) (161)
- An Experimental Model of Alcohol Feeding and Liver Injury in the Baboon 1 (1974) (158)
- Metabolism of alcohol. (1998) (158)
- In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O6-methylguanine transferase. (1988) (157)
- Carbohydrate-deficient transferrin, a marker for chronic alcohol consumption in different ethnic populations. (1988) (154)
- Carbohydrate-deficient transferrin and gamma-glutamyltransferase for the detection and monitoring of alcohol use: results from a multisite study. (2002) (154)
- Silymarin Retards the Progression of Alcohol-Induced Hepatic Fibrosis in Baboons (2003) (154)
- Alcohol, protein metabolism, and liver injury. (1980) (154)
- CYP2E1: from ASH to NASH. (2004) (153)
- Early perivenular sclerosis in alcoholic fatty liver: an index of progressive liver injury. (1977) (153)
- Age of alcoholism onset. II. Relationship to susceptibility to serotonin precursor availability. (1989) (153)
- Metabolism and metabolic effects of alcohol. (1980) (152)
- Increased carbon tetrachloride hepatotoxicity, and its mechanism, after chronic ethanol consumption. (1974) (151)
- Retinoic acid metabolism by a system reconstituted with cytochrome P-450. (1984) (151)
- New pathway for retinol metabolism in liver microsomes. (1985) (150)
- Induction of cytochrome P450IIE1 in the obese overfed rat. (1991) (148)
- Enhancement of dimethylnitrosamine metabolism and activation to a mutagen following chronic ethanol consumption. (1981) (147)
- Increased hepatotoxicity of acetaminophen after chronic ethanol consumption in the rat (1981) (147)
- Attenuation of alcohol‐induced hepatic fibrosis by polyunsaturated lecithin (1990) (146)
- Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. (1966) (145)
- The influence of alcohol on nutritional status. (2009) (145)
- Alcohol and the Liver: 1984 Update (1984) (144)
- Difference in hepatic metabolism of long- and medium-chain fatty acids: the role of fatty acid chain length in the production of the alcoholic fatty liver. (1967) (144)
- STUDIES OF ALCOHOLIC HYPERLIPEMIA AND ITS MECHANISM. (1963) (144)
- Differential depletion of carotenoids and tocopherol in liver disease (1993) (143)
- Metabolic effects of acetaldehyde. (1988) (142)
- The effect of acetaldehyde on mitochondrial function (1974) (142)
- Hepatitis C and alcohol. (2003) (142)
- Hepatotoxicity of vitamin A and ethanol in the rat. (1982) (140)
- Acetaldehyde oxidation by hepatic mitochondria: decrease after chronic ethanol consumption. (1975) (140)
- Gastric origin of the first-pass metabolism of ethanol in humans: effect of gastrectomy. (1989) (139)
- Hematologic effects of alcohol in man in the absence of nutritional deficiency. (1969) (139)
- Human gastric alcohol dehydrogenase: its inhibition by H2-receptor antagonists, and its effect on the bioavailability of ethanol. (1990) (138)
- Effect of ethanol on the amount and enzyme activities of hepatic rough and smooth microsomal membranes. (1973) (138)
- Formation of acetaldehyde adducts with ethanol-inducible P450IIE1 in vivo. (1988) (137)
- Effects of pyrazole on hepatic function and structure. (1970) (135)
- Effects of ethanol on the biogenesis of mitochondrial membranes and associated mitochondrial functions. (1970) (135)
- Effect of ethanol on ketone metabolism. (1970) (132)
- S-adenosyl-L-methionine: its role in the treatment of liver disorders. (2002) (132)
- Early fine structural changes in the human liver induced by alcohol. (1967) (130)
- Binding of acetaldehyde to rat liver microsomes: enhancement after chronic alcohol consumption. (1981) (129)
- Hepatic microsomal ethanol-oxidizing system: solubilization, isolation, and characterization. (1974) (126)
- Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon. (1997) (125)
- Aspirin increases blood alcohol concentrations in humans after ingestion of ethanol. (1990) (124)
- Alcohol, liver, and nutrition. (1991) (124)
- Polyenylphosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosis. (1997) (123)
- First pass metabolism of ethanol: an important determinant of blood levels after alcohol consumption. (1985) (123)
- Hepatic microsomal alcohol-oxidizing system. Affinity for methanol, ethanol, propanol, and butanol. (1975) (122)
- Medical disorders of alcoholism. Pathogenesis and treatment. (1982) (121)
- Respective roles of human cytochrome P-4502E1, 1A2, and 3A4 in the hepatic microsomal ethanol oxidizing system. (1998) (121)
- Induction and inhibition of hepatic microsomal and mitochondrial enzymes by ethanol. (1970) (121)
- Effect of ethanol on cholesterol and bile acid metabolism. (1972) (119)
- The role of alcoholism and liver disease in the appearance of serum antibodies against acetaldehyde adducts (1988) (119)
- Acetaldehyde and lactate stimulate collagen synthesis of cultured baboon liver myofibroblasts (1984) (119)
- Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis. (1982) (118)
- Hepatic Collagen Metabolism: Effect of Alcohol Consumption in Rats and Baboons (1972) (118)
- Alcohol and Hepatitis C (2001) (117)
- Purification and characterization of human liver cytochrome P-450-ALC. (1987) (117)
- Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1alpha in rats. (2008) (116)
- Ultrastructural changes in the small intestine induced by ethanol. (1972) (116)
- Immunohistochemical localization of ethanol-inducible P450IIE1 in the rat alimentary tract. (1990) (115)
- II. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease. (2003) (115)
- Microsomal ethanol-oxidizing system (MEOS): purification and properties of a rat liver system free of catalase and alcohol dehydrogenase. (1972) (115)
- Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic. (1977) (114)
- Polyunsaturated lecithin prevents acetaldehyde‐mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes (1992) (113)
- Ammonia as a source of gastric hypoacidity in patients with uremia. (1959) (113)
- Hypothesis: energy wastage in alcoholism and drug abuse: possible role of hepatic microsomal enzymes. (1976) (113)
- Attenuation of the ethanol‐induced hepatic redox change after chronic alcohol consumption in baboons: Metabolic consequences in vivo and in vitro (1981) (111)
- Interaction of ethanol with β‐carotene: Delayed blood clearance and enhanced hepatotoxicity (1992) (111)
- Effect of ethanol on plasma free fatty acids in man. (1962) (111)
- Biochemical and Morphological Alterations of Baboon Hepatic Mitochondria After Chronic Ethanol Consumption (1984) (110)
- The effect of alcohol ingestion on hepatic aromatase activity and plasma steroid hormones in the rat. (1979) (108)
- Animal models of chronic ethanol toxicity. (1994) (107)
- Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease (1983) (107)
- Microsomal ethanol oxidizing system (MEOS): current status of its characterization and its role. (1977) (106)
- Decreased cytochrome oxidase activity in hepatic mitochondria after chronic ethanol consumption and the possible role of decreased cytochrome aa3 content and changes in phospholipids. (1984) (106)
- Muscle damage produced by chronic alcohol consumption. (1976) (106)
- Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. (1983) (105)
- Characteristics of acetaldehyde oxidation in rat liver mitochondria. (1976) (105)
- Effects of ranitidine on blood alcohol levels after ethanol ingestion. Comparison with other H2-receptor antagonists. (1992) (105)
- Effect of chronic feeding on the activities and submicrosomal distribution of reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase and the demethylases for aminopyrine and ethylmorphine. (1973) (104)
- Alcohol and lipids. (1998) (103)
- First-pass metabolism of ethanol is predominantly gastric. (1993) (102)
- Increased circulating products of lipid peroxidation in patients with alcoholic liver disease. (1998) (102)
- Alcoholism, alcohol, and drugs. (1971) (102)
- In vivo induction of hepatic P4502E1 by ethanol: role of increased enzyme synthesis. (1993) (102)
- Aspartate Aminotransferase to Platelet Ratio Index in Patients with Alcoholic Liver Fibrosis (2006) (102)
- Alcohol-induced gastric and duodenal lesions in man. (1978) (102)
- Alcohol and the liver: metabolism of alcohol and its role in hepatic and extrahepatic diseases. (2000) (102)
- Models of alcoholic liver disease in rodents: a critical evaluation. (2001) (101)
- Effect of concentration of ingested ethanol on blood alcohol levels. (1991) (101)
- Alcoholism is associated with hepatitis C but not hepatitis B in an urban population. (1996) (100)
- Plasma amino acid abnormalities in the alcoholic: respective role of alcohol, nutrition, and liver injury. (1978) (100)
- Ethnic differences in gastric sigma-alcohol dehydrogenase activity and ethanol first-pass metabolism. (1996) (99)
- Impaired oxygen utilization. A new mechanism for the hepatotoxicity of ethanol in sub-human primates. (1989) (99)
- Alcohol-induced Malabsorption of Vitamin B12 in Man (1969) (98)
- Mechanism for selective perivenular hepatotoxicity of ethanol. (1982) (98)
- S-Adenosylmethionine: molecular, biological, and clinical aspects--an introduction. (2002) (98)
- Prolonged ethanol consumption increases testosterone metabolism in the liver. (1976) (98)
- Ultrastructure of initial stages of perivenular fibrosis in alcohol-fed baboons. (1982) (97)
- Reduced Nicotinamide-adenine Dinucleotide Phosphate Oxidase: Activity Enhanced by Ethanol Consumption (1970) (96)
- Absorption of orally administered neomycin and kanamycin with special reference to patients with severe hepatic and renal disease. (1960) (96)
- Chronic ethanol consumption alters rat liver plasma membranes and potentiates release of alkaline phosphatase. (1985) (95)
- Animal models of ethanol dependence and liver injury in rats and baboons. (1976) (95)
- Ethanol and lipids. (1984) (94)
- Hepatic phosphatidylethanolamine methyltransferase activity is decreased by ethanol and increased by phosphatidylcholine. (1994) (94)
- The metabolism of alcohol. (1976) (93)
- THE EFFECT OF ETHANOL UPON SYSTEMIC AND HEPATIC BLOOD FLOW IN MAN. (1963) (92)
- Hepatotoxicity of ethanol. (1991) (91)
- Liver adaptation and injury in alcoholism. (1973) (91)
- Mechanisms of ethanol-drug-nutrition interactions. (1994) (91)
- Effect of hepatic vitamin A depletion on the liver in humans and rats. (1983) (89)
- Hepatic and metabolic effects of alcohol. (1966) (89)
- Metabolic derangement induced by alcohol. (1967) (89)
- Hepatic ethanol metabolism: respective roles of alcohol dehydrogenase, the microsomal ethanol-oxidizing system, and catulase. (1976) (87)
- Role of S-adenosyl-L-methionine in the treatment of liver diseases. (1999) (86)
- Hepatic and metabolic effects of alcohol (1966 to 1973). (1973) (86)
- Acute effects of ethanol on hepatic protein synthesis and secretion in the rat. (1980) (86)
- Effect of chronic ethanol ingestion on fatty acid oxidation by hepatic mitochondria. (1975) (85)
- Lack of alcohol dehydrogenase isoenzyme activities in the stomach of Japanese subjects. (1991) (85)
- Inflammation and Repair in Viral Hepatitis C (2008) (84)
- Serum carbohydrate‐deficient transferrin: Mechanism of increase after chronic alcohol intake (1995) (84)
- Lipid peroxidation as a mechanism of alcoholic liver injury: role of iron mobilization and microsomal induction. (1988) (83)
- Changes in carbohydrate-deficient transferrin levels after alcohol withdrawal. (1988) (83)
- Efficacy of a high and accelerated dose of hepatitis B vaccine in alcoholic patients: a randomized clinical trial. (1997) (83)
- Hepatic and other medical disorders of alcoholism: from pathogenesis to treatment. (1998) (83)
- Enhanced pulmonary and intestinal activation of procarcinogens and mutagens after chronic ethanol consumption in the rat (1981) (83)
- Contribution of oropharynx microflora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion. (1981) (82)
- Medical and Nutritional Complications of Alcoholism (1992) (82)
- Alterations in Endothelial Fenestrations in Liver Sinusoids of Baboons Fed Alcohol: A Scanning Electron Microscopic Study (1984) (81)
- Diagnostic value of serum procollagen peptide measurements in alcoholic liver disease. (1984) (80)
- Interactions between alcohol and beta-carotene in patients with alcoholic liver disease. (1994) (80)
- Ethanol consumption increases nitric oxide production in rats, and its peroxynitrite-mediated toxicity is attenuated by polyenylphosphatidylcholine. (2002) (80)
- Plasma alpha amino-n-butyric acid to leucine ratio: an empirical biochemical marker of alcoholism. (1976) (80)
- Hypervitaminosis a: A liver lover's lament (1988) (80)
- EFFECTS OF ETHANOL ON PLASMA LIPIDS IN MAN. (1963) (79)
- Hepatic redox state: attenuation of the acute effects of ethanol induced by chronic ethanol consumption. (1974) (78)
- Increased Hepatic Oxygenation following Ethanol Administration in the Baboon 1 (1977) (78)
- Hepatic microsomal ethanol oxidizing system (MEOS): differentiation from alcohol dehydrogenase and NADPH oxidase. (1970) (77)
- Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells. (2007) (75)
- Characterization of shuttle mechanisms for the transport of reducing equivalents into mitochondria. (1973) (74)
- Hepatic, Metabolic, and Nutritional Disorders of Alcoholism: From Pathogenesis to Therapy (2000) (74)
- Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes. (1982) (74)
- Pathogenesis of postprandial hyperlipemia in rats fed ethanol-containing diets. (1973) (74)
- EFFECTS OF CHRONIC ETHANOL ADMINISTRATION ON INTESTINAL ABSORPTION IN MAN IN THE ABSENCE OF NUTRITIONAL DEFICIENCY * (1975) (74)
- Metabolic Aspects of Alcoholism (1977) (74)
- Diagnostic utility of laboratory tests in alcoholic liver disease. (1994) (73)
- New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments (2004) (73)
- Fatty acid‐binding protein: A major contributor to the ethanol‐induced increase in liver cytosolic proteins in the rat (1987) (73)
- SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primates. (2003) (73)
- Choline fails to prevent liver fibrosis in ethanol‐fed baboons but causes toxicity (1985) (73)
- Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liver. (2003) (73)
- Mechanism of the preventive effect of ethanol on acetaminophen-induced hepatoxicity. (1981) (73)
- S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings. (2002) (72)
- Alcohol metabolism: role in toxicity and carcinogenesis. (2003) (72)
- Alcohol and the liver: metabolism of ethanol, metabolic effects and pathogenesis of injury. (2009) (72)
- Pathogenesis and early diagnosis of alcoholic liver injury. (1978) (72)
- Effects of ethanol and fat on the transport of reducing equivalents into rat liver mitochondria. (1973) (72)
- NAD+-dependent retinol dehydrogenase in liver microsomes. (1987) (71)
- Hepatic and metabolic effects of ethanol: pathogenesis and prevention. (1994) (71)
- Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in rats. (1997) (71)
- Acetaldehyde adducts and autoantibodies against VLDL and LDL in alcoholics. (1993) (71)
- Interaction of ethanol with drugs, hepatotoxic agents, carcinogens and vitamins. (1990) (71)
- Dilinoleoylphosphatidylcholine decreases LPS-induced TNF-α generation in Kupffer cells of ethanol-fed rats: respective roles of MAPKs and NF-κB (2002) (70)
- Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding. (1984) (70)
- Humoral immune response to acetaldehyde adducts in alcoholic patients. (1986) (70)
- Role of acetone, dietary fat and total energy intake in induction of hepatic microsomal ethanol oxidizing system. (1988) (70)
- DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells. (2002) (70)
- Ethanol binding to hepatic microsomes. Its increase by ethanol consumption. (1971) (70)
- Metabolic effects of ethanol and its interaction with other drugs, hepatotoxic agents, vitamins, and carcinogens: a 1988 update. (1988) (70)
- Polyenylphosphatidylcholine attenuates non-alcoholic hepatic fibrosis and accelerates its regression. (1996) (70)
- Ethnic and gender differences in ethanol metabolism. (2000) (69)
- Effect of chronic alcohol ingestion on the biosynthesis of steroids in rat testicular homogenate in vitro. (1980) (69)
- Metabolism of alcohol by human gastric cells: relation to first-pass metabolism. (1996) (69)
- Depression, suicide, and aggression in alcoholics and their relationship to plasma amino acids (1984) (68)
- Study of agents for the prevention of the fatty liver produced by prolonged alcohol intake. (1966) (68)
- Desmin distinguishes cultured fat-storing cells from myofibroblasts, smooth muscle cells and fibroblasts in the rat. (1988) (68)
- Tissue inhibitor of metalloproteinase is increased in the serum of precirrhotic and cirrhotic alcoholic patients and can serve as a marker of fibrosis (1994) (68)
- Leptin enhances α1(I) collagen gene expression in LX‐2 human hepatic stellate cells through JAK‐mediated H2O2‐dependent MAPK pathways (2006) (68)
- Alcohol alters hepatic FoxO1, p53, and mitochondrial SIRT5 deacetylation function. (2008) (68)
- Symptomatic intestinal disaccharidase deficiency in alcoholics. (1977) (67)
- NADPH-dependent oxidation of methanol, ethanol, propanol and butanol by hepatic microsomes. (1974) (67)
- The contribution of the stomach to ethanol oxidation in the rat. (1987) (67)
- Effect of chronic ethanol feeding on hepatic microsomal glycerophosphate acyltransferase activity. (1973) (67)
- Alcohol consumption enhances fatty acid ω‐oxidation, with a greater increase in male than in female rats (1993) (67)
- Fatty liver produced by dietary deficiencies: its pathogenesis and potentiation by ethanol. (1969) (67)
- I. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease: effects on drinking behavior by nurse/physician teams. (2003) (67)
- Acetaldehyde production and transfer by the perfused human placental cotyledon. (1988) (66)
- Effect of chronic ethanol consumption on activation of nitrosopyrrolidine to a mutagen by rat upper alimentary tract, lung, and hepatic tissue. (1985) (65)
- Herman Award Lecture, 1993: a personal perspective on alcohol, nutrition, and the liver. (1993) (65)
- Value of fibrosis markers for staging liver fibrosis in patients with precirrhotic alcoholic liver disease. (2008) (65)
- NH2-terminal sequence analyses of four rat hepatic microsomal cytochromes P-450. (1984) (65)
- Interaction of methadone and ethanol metabolism. (1978) (64)
- Isoelectric focusing/western blotting: a novel and practical method for quantitation of carbohydrate-deficient transferrin in alcoholics. (1991) (64)
- The effects of alcoholic liver disease and alcohol ingestion on sex hormone levels. (1978) (63)
- Prevention of acetaminophen-induced hepatotoxicity by acute ethanol administration in the rat: comparison with carbon tetrachloride-induced hepatoxicity. (1981) (63)
- To drink (moderately) or not to drink? (1984) (63)
- Induction of cytochrome P-4502E1 by ethanol in rat Kupffer cells. (1996) (63)
- Increased type I procollagen mRNA levels and in vitro protein synthesis in the baboon model of chronic alcoholic liver disease. (1985) (63)
- Spontaneous regression of hepatocellular carcinoma. (1982) (63)
- Increased vitamin A in esophagus and other extrahepatic tissues after chronic ethanol consumption in the rat. (1986) (62)
- Effect of chronic ethanol consumption on aldehyde dehydrogenase activity in the baboon. (1981) (61)
- Ethanol metabolism in vivo by the microsomal ethanol-oxidizing system in deermice lacking alcohol dehydrogenase (ADH). (1984) (61)
- Colchicine treatment of alcoholic cirrhosis: a randomized, placebo-controlled clinical trial of patient survival. (2005) (61)
- A method for the determination of "free" acetaldehyde in plasma. (1979) (61)
- Energy wastage in rats given drugs that induce microsomal enzymes. (1975) (61)
- Retinol forms retinoic acid via retinal. (1992) (61)
- Serum procollagen type III N-terminal peptides and laminin P1 peptide in alcoholic liver disease. (1987) (61)
- P3 in alcoholics with disordered regulation of aggression (1988) (61)
- Decreased hepatic vitamin A after drug administration in men and in rats. (1984) (60)
- Microsomal ethanol-oxidizing system. (1987) (59)
- Ethanol and lipid metabolism. (1999) (59)
- Comparison of blood alcohol concentrations after beer and whiskey. (1993) (59)
- Effect of chronic ethanol ingestion on intestinal metabolism and mutagenicity of benzo(α)pyrene (1978) (59)
- Analysis of risk factors for chronic hepatic encephalopathy: the role of Helicobacter pylori infection (1998) (58)
- Red blood cells: a new major modality for acetaldehyde transport from liver to other tissues. (1987) (58)
- Dilinoleoylphosphatidylcholine decreases acetaldehyde-induced TNF-alpha generation in Kupffer cells of ethanol-fed rats. (2002) (57)
- Pathogenesis of precirrhotic portal hypertension in alcohol-fed baboons. (1985) (57)
- Alcoholic liver injury: pathogenesis and therapy in 2001. (2001) (57)
- Molecular regulation of ethanol-inducible cytochrome P450-IIEI in hamsters. (1988) (56)
- Structural and functional effects of ethanol on hepatic mitochondria. (1972) (56)
- Effect of acetaldehyde on fatty acid oxidation and ketogenesis by hepatic mitochondria. (1975) (56)
- Interaction of ethanol and pyrazole with hepatic microsomes. (1971) (56)
- An experimental model of alcohol feeding and liver injury in the baboon. (2009) (56)
- Ranitidine increases the bioavailability of imbibed alcohol by accelerating gastric emptying. (1996) (56)
- Cytochrome P4502E1 primes macrophages to increase TNF-alpha production in response to lipopolysaccharide. (2005) (55)
- International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC Working Paper No. 15/2. Metabolism and metabolic effects of ethanol, including interaction with drugs, carcinogens and nutrition. (1987) (55)
- Measurement of carbohydrate-deficient transferrin by isoelectric focusing/western blotting and by micro anion-exchange chromatography/radioimmunoassay: comparison of diagnostic accuracy. (1992) (55)
- Demonstration of dissimilar acute haemodynamic effects of ethanol and acetaldehyde. (1979) (54)
- Oxidation of ethanol to acetaldehyde by bronchopulmonary washings: role of bacteria. (1986) (54)
- Adipose differentiation-related protein is a reliable lipid droplet marker in alcoholic fatty liver of rats. (2008) (54)
- Polyenylphosphatidylcholine opposes the increase of cytochrome P-4502E1 by ethanol and corrects its iron-induced decrease. (1999) (54)
- Metabolism of Ethanol (1992) (54)
- Concentration dependence of ethanol metabolism in vivo in rats and man. (1978) (54)
- Immunohistochemical detection of proliferating lipocytes in regenerating rat liver (1990) (53)
- Agonist: gastric first pass metabolism of alcohol. (1994) (53)
- Attenuation of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC). (2000) (52)
- Hepatic triacylglycerol synthesizing activity during progression of alcoholic liver injury in the baboon. (1984) (52)
- Effects of alcohol on hepatic transport of proteins. (1982) (52)
- Hepatitis C virus antibody in alcoholic patients. Association with the presence of portal and/or lobular hepatitis. (1993) (52)
- Changes in vitamin A status after acute ethanol administration in the rat. (1982) (52)
- Respective role of superoxide and hydroxyl radical in the activity of the reconstituted microsomal ethanol-oxidizing system. (1978) (51)
- Differences in hepatic and metabolic changes after acute and chronic alcohol consumption. (1975) (50)
- Acetaldehyde binding increases the catabolism of rat serum low-density lipoproteins. (1987) (50)
- Concentration dependency of ethanol elimination rates in baboons: effect of chronic alcohol consumption. (1980) (50)
- Direct measurement of neutral collagenase activity in homogenates from baboon and human liver. (1981) (50)
- Interaction of acute ethanol administration with acetaminophen metabolism and toxicity in rats fed alcohol chronically. (1984) (49)
- Effect of alcohol on growth, bone density and muscle magnesium in the rat. (1965) (49)
- Inhibitory effect of ethanol on canine exocrine pancreatic secretion. (1972) (49)
- Dilinoleoylphosphatidylcholine prevents transforming growth factor-beta1-mediated collagen accumulation in cultured rat hepatic stellate cells. (2002) (49)
- Metabolic Effects of Alcohol on the Liver (1977) (49)
- Utility of carbohydrate-deficient transferrin as a marker of relapse in alcoholic patients. (1995) (48)
- Experimental alcoholic hepatic injury in man: ultrastructural changes. (1967) (48)
- Acute and chronic effects of ethanol and its metabolites on vascular production of prostacyclin in rats. (1987) (48)
- Alcohol and cancer. (1990) (48)
- INTERFERENCE OF ETHANOL IN HEPATIC CELLULAR METABOLISM * (1975) (46)
- Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1. (2003) (46)
- Alcoholic fatty liver. (1969) (46)
- Liver fibrosis in alcoholics. Detection by Fab radioimmunoassay of serum procollagen III peptides. (1986) (46)
- Role of medium-chain triglycerides in the alcohol-mediated cytochrome P450 2E1 induction of mitochondria. (2007) (46)
- First pass metabolism of ethanol. (1994) (46)
- beta-Carotene beadlets potentiate hepatotoxicity of alcohol. (1997) (45)
- Significant increase of blood alcohol by cimetidine after repetitive drinking of small alcohol doses. (1995) (45)
- Effect of ethanol on fatty acid metabolism in liver slices (1959) (45)
- Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine. (2003) (44)
- Lack of correlation between hepatic mitochondrial membrane structure and functions in ethanol-fed rats. (1982) (44)
- Interaction of ethanol with vitamin A. (1983) (44)
- Interaction of ethanol with enflurane metabolism and toxicity: role of P450IIE1. (1990) (43)
- Effect of drug administration on the activity of the hepatic microsomal ethanol oxidizing system. (1970) (43)
- High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration (1989) (43)
- Prevention and treatment of liver fibrosis based on pathogenesis. (1999) (43)
- Ethanol impairs tryptophan transport into the brain and depresses serotonin. (1981) (43)
- Effect of ethanol administration on the metabolism of ethanol in baboons. (1983) (43)
- Hyperuricemia induced by alcohol. (1965) (42)
- Acarbose attenuates experimental non-alcoholic steatohepatitis. (2004) (42)
- Increased alcohol dehydrogenase independent ethanol oxidation at high ethanol concentrations in isolated rat hepatocytes: the effect of chronic ethanol feeding. (1981) (42)
- Carotenoids and tocopherols in various hepatobiliary conditions. (1995) (42)
- Purification of NADPH:cytochrome c (cytochrome P-450) reductase from hamster liver microsomes by detergent extraction and affinity chromatography. (1987) (41)
- Effects of chronic ethanol intake on mobilization and excretion of cholesterol in baboons. (1985) (41)
- Determinants of plasma free acetaldehyde levels during the oxidation of ethanol: effects of chronic ethanol feeding. (1981) (41)
- Pathogenesis and treatment of alcoholic liver disease: progress over the last 50 years. (2005) (41)
- Hepatic lipid in morbid obesity. Assessment at and subsequent to jejunoileal bypass. (1974) (41)
- Assessment of the role of non-ADH ethanol oxidation in vivo and in hepatocytes from deermice. (1986) (40)
- Dependence of ethanol-induced redox shift on hepatic oxygen tensions prevailing in vivo. (1985) (40)
- Potentiation of ethanol-induced hepatic vitamin A depletion by phenobarbital and butylated hydroxytoluene. (1987) (40)
- Ethanol, the liver, and the gastrointestinal tract. (1981) (40)
- Effects of alcohol consumption on eight circulating markers of liver fibrosis. (2002) (40)
- Ethanol oxidation by intestinal microsomes: increased activity after chronic ethanol administration. (1979) (40)
- Hepatic microsomal ethanol-oxidizing system (MEOS): dissociation from reduced nicotinamide adenine dinucleotide phosphate oxidase and possible role of form I of cytochrome P-450. (1975) (40)
- Alcohol and retinoids. (2001) (39)
- Increased hepatic production of alpha-amino-n-butyric acid after chronic alcohol consumption in rats and baboons. (1980) (39)
- Biochemical tests for the detection of alcoholism: comparison of plasma alpha-amino-n-butyric acid with other available tests. (1978) (39)
- [37] The Microsomal ethanol oxidizing systems (MEOS) (1978) (39)
- Detection of alcoholism relapse: comparative diagnostic value of MCV, GGTP, and AANB. (1979) (39)
- Ethanol-metabolizing pathways in deermice. Estimation of flux calculated from isotope effects. (1987) (39)
- Interaction of drugs and retinol. (1986) (39)
- Dilinoleoylphosphatidylcholine decreases hepatic stellate cell activation. (1999) (39)
- Ethanol increases glycosyl transferase activity in the hepatic Golgi apparatus. (1973) (39)
- Collagen‐acetaldehyde adducts in alcoholic and nonalcoholic liver diseases (1994) (38)
- Acute and chronic effects of ethanol on intestinal lipid metabolism. (1975) (38)
- Aetiology and pathogenesis of alcoholic liver disease. (1993) (38)
- Effect of ethanol and vitamin A deficiency on epithelial cell proliferation and structure in the rat esophagus. (1987) (38)
- Intestinal lymph formation and fat absorption: stimulation by acute ethanol administration and inhibition by chronic ethanol administration and inhibition by chronic ethanol feeding. (1975) (38)
- LIVER DISEASE AND ALCOHOL: FATTY LIVER, ALCOHOLIC HEPATITIS, CIRRHOSIS, AND THEIR INTERRELATIONSHIPS * (1975) (37)
- Collagen synthesis by liver stellate cells is released from its normal feedback regulation by acetaldehyde-induced modification of the carboxyl-terminal propeptide of procollagen. (1997) (37)
- Effects of Ethanol on Lipid, Uric Acid, Intermediary, and Drug Metabolism, Including the Pathogenesis of the Alcoholic Fatty Liver (1971) (37)
- Bioavailability of alcohol: role of gastric metabolism and its interaction with other drugs. (1994) (37)
- Interaction of ethanol with acetaminophen metabolism in the baboon. (1984) (37)
- Pharmacology and metabolism of alcohol, including its metabolic effects and interactions with other drugs. (1999) (36)
- Characterization of the increased binding of acetaldehyde to red blood cells in alcoholics. (1989) (36)
- Chlorzoxazone pharmacokinetics as a marker of hepatic cytochrome P4502E1 in humans (1998) (36)
- Ethanol oxidation by isolated hepatocytes from ethanol-treated and control rats; factors contributing to the metabolic adaptation after chronic ethanol consumption. (1978) (36)
- Experimental Alcoholic Hepalitis: A New Primate Model (1973) (36)
- Comparison of animal and vegetable protein sources in the dietary management of hepatic encephalopathy. (1983) (36)
- New pathway of ethanol metabolism in the liver. (1970) (36)
- Characterization of the cytochrome P-450 monooxygenase system of hamster liver microsomes. Effects of prior treatment with ethanol and other xenobiotics. (1987) (36)
- Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment. (2001) (35)
- Origin of breath acetaldehyde during ethanol oxidation. Effect of long-term cigarette smoking. (1982) (35)
- Dilinoleoylphosphatidylcholine protects human low density lipoproteins against oxidation. (2000) (35)
- The effect of chronic alcohol feeding on lipid peroxidation in microsomes: lack of relationship to hydroxyl radical generation. (1984) (35)
- Increased hepatic retinal dehydrogenase activity after phenobarbital and ethanol administration. (1989) (35)
- Effect of abstinence on the blood acetaldehyde response to a test dose of alcohol in alcoholics. (1987) (35)
- Alcoholism in Vietnam and Korea veterans: a long term follow-up. (1984) (34)
- Effect of chronic ethanol consumption and acetaldehyde on partial reactions of oxidative phosphorylation and CO2 production from citric acid cycle intermediates. (1976) (34)
- Increased microsomal oxidation of ethanol by cytochrome P-450 and hydroxyl radical-dependent pathways after chronic ethanol consumption. (1984) (34)
- Alcohol-induced pancreatic oxidative stress: protection by phospholipid repletion. (1999) (34)
- Chronic alcoholic gastritis. Roles of alcohol and Helicobacter pylori. (1991) (34)
- Upstream structure of human ADH7 gene and the organ distribution of its expression. (1995) (34)
- Non-uniformity of blood ethanol elimination: its exaggeration after chronic consumption. (1978) (34)
- Dilinoleoylphosphatidylcholine decreases LPS-induced TNF-alpha generation in Kupffer cells of ethanol-fed rats: respective roles of MAPKs and NF-kappaB. (2002) (33)
- The Microsomal Ethanol Oxidizing System and Its Interaction with Other Drugs, Carcinogens, and Vitamins (1987) (33)
- Alcohol and malnutrition in the pathogenesis of liver disease.. (1975) (33)
- Factors contributing to the adaptive increase in ethanol metabolism due to chronic consumption of ethanol. (1977) (32)
- Hypogonadism and feminization in the male: a triple effect of alcohol. (1979) (32)
- Alcoholic liver injury: experimental models in rats and baboons. (1975) (32)
- Carbohydrate deficient transferrin in alcoholic liver disease: mechanisms and clinical implications. (1999) (32)
- Effects of chronic alcohol feeding on thiamin status: biochemical and neurological correlates. (1981) (32)
- Effects of ethanol on prostanoid production by liver fat‐storing cells (1993) (31)
- Sex dependent effect of chronic ethanol consumption in rats on hepatic microsome mediated mutagenicity of benzo[a]pyrene. (1981) (31)
- The combined effects of protein deficiency and chronic ethanol administration on rat ethanol metabolism (1986) (31)
- Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism. (1992) (31)
- Medical and Nutritional Complications of Alcoholism: Mechanisms and Management (2012) (31)
- Gastric juice urease activity as a diagnostic test for Helicobacter pylori infection. (1997) (31)
- Dilinoleoylphosphatidylcholine selectively modulates lipopolysaccharide-induced Kupffer cell activation. (1999) (31)
- Ethanol dependence and tolerance: a nutritionally controlled experimental model in the rat. (1973) (31)
- Gender differences in medium-chain dicarboxylic aciduria in alcoholic men and women. (1999) (30)
- The microsomal ethanol oxidizing system: its role in ethanol and xenobiotic metabolism. (1988) (30)
- Human immunodeficiency virus and hepatitis B virus infections in a New York City alcoholic population. (1992) (30)
- Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1. (2001) (30)
- Serum carbohydrate-deficient transferrin: mechanism of increase after chronic alcohol intake. (1996) (30)
- Ultrastructural localization of type III procollagen in baboon liver. (1986) (30)
- The determination of cytochrome P450 2E1-dependent p-nitrophenol hydroxylation by high-performance liquid chromatography with electrochemical detection. (1996) (30)
- Improved methods for the measurement of acetaldehyde concentrations in plasma and red blood cells. (1986) (30)
- The significance and characterization of hepatic microsomal ethanol oxidation in the liver. (1973) (30)
- Metabolism of ethanol and alcoholism: racial and acquired factors. (1972) (30)
- Ethanoit—A Hepatotoxic Drug (1968) (30)
- Effect of ethanol on plasma glycerol in man. (1967) (30)
- Pathogenesis of the hypertriglyceridemia at early stages of alcoholic liver injury in the baboon. (1986) (30)
- F2-isoprostane and 4-hydroxynonenal excretion in human bile of patients with biliary tract and pancreatic disorders. (1997) (30)
- Metabolism and metabolic effects of ethanol. (1981) (29)
- Metabolism of ethanol and associated hepatotoxicity. (1991) (29)
- The Effects of Ethanol and Diet on Hepatic and Serum γ-Glutamyltranspeptidase Activities in Rats (1985) (29)
- Effect of chronic alcohol use on hepatic testosterone 5-alpha-A-ring reductase in the baboon and in the human being. (1979) (29)
- Chronic ethanol consumption inhibits repair of dimethylnitrosamine-induced DNA alkylation. (1988) (29)
- Zonal redox changes as a cause of selective perivenular hepatotoxicity of alcohol (1983) (29)
- Cytotoxicity of mononuclear cells and vulnerability of hepatocytes in alcoholic fatty liver of baboons. (2008) (29)
- Effects of ethanol on hepatic protein secretion and microtubules. Possible mediation by acetaldehyde. (1981) (29)
- Local Factors in Ascites Formation during Sodium Retention in Cirrhosis (1963) (29)
- Metabolic Consequences of Ethanol (1994) (28)
- Inducibility of cytochromes P-4502E1 and P-4501A1 in the rat pancreas. (1998) (28)
- Alcoholic liver disease: from pathophysiology to therapy. (2005) (28)
- Acetaldehyde-collagen adducts in CCl4-induced liver injury in rats. (1990) (28)
- Polyenylphosphatidylcholine decreases alcoholic hyperlipemia without affecting the alcohol-induced rise of HDL-cholesterol. (1997) (28)
- Microsomal acetaldehyde oxidation is negligible in the presence of ethanol. (1998) (28)
- HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM: ISOLATION AND RECONSTITUTION (1977) (27)
- An Overview of Current and Emerging Markers of Alcoholism (1992) (27)
- Dilinoleoylphosphatidylcholine is the active antioxidant of polyenylphosphatidylcholine. (1999) (27)
- Effects of chronic ethanol consumption on carcinogen activating and detoxifying systems in rat upper alimentary tract tissue. (1989) (27)
- Isolation and Culture of Myofibroblasts from Rat Liver (1985) (27)
- Oxidation of LDL in baboons is increased by alcohol and attenuated by polyenylphosphatidylcholine. (1999) (27)
- Respective roles of the microsomal ethanol oxidizing system and catalase in ethanol metabolism by deermice lacking alcohol dehydrogenase. (1987) (27)
- Effects of vitamin A and ethanol on liver plasma membrane fluidity (1988) (27)
- Gender Differences in the Response of Hepatic Fatty Acids and Cytosolic Fatty Acid-Binding Capacity to Alcohol Consumption in Rats (1991) (27)
- Severity ofHelicobacter-induced gastric injury correlates with gastric juice ammonia (1991) (26)
- Malnutrition and liver disease--an overemphasized relationship. (1968) (26)
- A trial of "standard" outpatient alcoholism treatment vs. a minimal treatment control. (2002) (26)
- Helicobacter pylori and nonulcer dyspepsia. (1999) (26)
- In vivo roles of alcohol dehydrogenase (ADH), catalase and the microsomal ethanol oxidizing system (MEOS) in deermice. (1985) (26)
- Susceptibility to alcohol-related liver injury. (1994) (26)
- Alcohol-nutrition interaction: 1984 update. (1984) (25)
- Hepatic microsomal alcohol-oxidizing system in normal and acatalasemic mice: its dissociation from the peroxidatic activity of catalase-H2O2. (1975) (25)
- The microsomal ethanol oxidizing system (MEOS). (1978) (25)
- Increases in skeletal calcium and femur cortex thickness produced by undernutrition. (1969) (25)
- Hepatotoxicity of acetaldehyde. (1980) (25)
- Molecular cloning and chromosomal localization of the ADH7 gene encoding human class IV (sigma) ADH. (1996) (25)
- Effect of chronic alcohol consumption on ethanol and acetaldehyde metabolism. (1975) (25)
- Effects of H2-receptor antagonists on gastric alcohol dehydrogenase activity (1991) (25)
- Relationship between changes in plasma amino acids and depression in alcoholic patients. (1984) (25)
- Acetaldehyde-collagen adducts in N-nitrosodimethylamine-induced liver cirrhosis in rats. (1993) (24)
- Mechanism of the aspirin-induced rise in blood alcohol levels. (1999) (24)
- Free fatty acid turnover and triglyceride metabolism after ethanol ingestion in man. (1965) (24)
- Molecular cloning of human class IV alcohol dehydrogenase cDNA. (1994) (24)
- Gastric ethanol metabolism and gastritis: interactions with other drugs, Helicobacter pylori, and antibiotic therapy (1957-1997)--a review. (1997) (24)
- Exaggerated acetaldehyde response after ethanol administration during pregnancy and lactation in rats. (1985) (24)
- Depression of biliary glutathione excretion by chronic ethanol feeding in the rat. (1984) (23)
- A public health strategy against alcoholism and its complications. (1978) (23)
- Toxicity of β-carotene and its exacerbation by acetaldehyde in HepG2 cells (2001) (23)
- Frequency of Hyperprolinemia in Alcoholic Liver Cirrhosis: Relationship to Blood Lactate (1984) (23)
- Plasma glutamate dehydrogenase: clinical application in patients with alcoholic liver disease. (1980) (23)
- Increase of microsomal glucose-6-phosphatase activity after chronic ethanol administration. (1973) (23)
- INTERACTIONS OF ALCOHOL AND NUTRITION Introduction to a Symposium (1983) (23)
- The effect of the prostaglandin analogue-misoprostol on rat liver mitochondria after chronic alcohol feeding. (1991) (22)
- Alcohol-nutrition interaction. (1979) (22)
- Cytogenetic damage of bone marrow cells produced by chronic alcohol consumption. (1981) (22)
- Increased hepatotoxicity of acetaminophen after chronic ethanol consumption in the rat. (1981) (22)
- Cytotoxicity of Lymphocytes in Experimental Alcoholic Liver Injury in the Baboon 1 (1976) (22)
- DLPC and SAMe combined prevent leptin‐stimulated TIMP‐1 production in LX‐2 human hepatic stellate cells by inhibiting H2O2‐mediated signal transduction (2006) (22)
- Association between low plasma tryptophan and blackouts in male alcoholic patients. (1985) (22)
- Reduction of gastric ammonia by ampicillin in normal and azotemic subjects. (1976) (22)
- Decrease of Ethanol-Induced Fatty Liver by Ethyl α-p-Chlorophenoxyisobutyrate.∗ (1966) (22)
- Dilinoleoylphosphatidylcholine is responsible for the beneficial effects of polyenylphosphatidylcholine on ethanol-induced mitochondrial injury in rats. (2002) (22)
- Interactive effects of dietary protein and ethanol on rat pancreas. Protein synthesis and enzyme secretion. (1990) (21)
- Acetaldehyde and lactate stimulate collagen synthesis of cultured baboon liver myofibroblasts. (1984) (21)
- Nutrition: Medical Problems of Alcoholism (1992) (21)
- Metabolism of ethanol in rat gastric cells and its inhibition by cimetidine. (1995) (21)
- New technique for the isolation of functional rat pancreatic mitochondria and its application to models of pancreatic injury. (1986) (20)
- Mediation by nitric oxide of the stimulatory effects of ethanol on blood flow. (2002) (20)
- Pathophysiology of alcoholic liver disease. (1988) (20)
- The microsomal ethanol oxidizing system mediates metabolic tolerance to ethanol in deermice lacking alcohol dehydrogenase. (1989) (19)
- Relation of alcoholic liver injury to cirrhosis. (1975) (19)
- Oxidation of ethanol by hepatic microsomes of acatalasemic mice. (1974) (19)
- Vitamin A treatment of sexual dysfunction in male alcoholics. (1988) (19)
- Increase in tryptophan oxygenase activity in alcoholic patients. (1988) (19)
- Nutrition in the alcoholic. (1979) (19)
- Pathogenesis and treatment of liver fibrosis in alcoholics: 1996 update. (1997) (19)
- Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1. (2003) (19)
- Polyenylphosphatidylcholine protects against alcohol but not iron-induced oxidative stress in the liver. (2000) (19)
- Immunohistochemical determination of hepatic cytochrome P-4502E1 in formalin-fixed, paraffin-embedded sections. (1997) (18)
- Effect of chronic ethanol ingestion on mitochondrial permeability and the transport of reducing equivalents. (1972) (18)
- DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1. (2005) (18)
- Enhanced stimulatory effect of high density lipoproteins (HDL) and other agonists on vascular prostacyclin production in rats fed alcohol-containing diets. (1989) (18)
- Alcohol, liver injury and protein metabolism (1980) (17)
- Transport of acetaldehyde in red blood cells. (1987) (17)
- Alcohol, other drugs, and the liver. (1968) (17)
- Metabolism of ethanol and some associated adverse effects on the liver and the stomach. (1998) (17)
- Microsomal ethanol oxidizing system (MEOS): Interaction with ethanol, drugs and carcinogens (1983) (17)
- Alcohol levels are increased in social drinkers receiving ranitidine (2000) (17)
- The combination of S-adenosylmethionine and dilinoleoylphosphatidylcholine attenuates nonalcoholic steatohepatitis produced by a high-fat diet in rats ☆ (2007) (17)
- Plasma amino acids in the alcoholic: nutritional aspects. (1983) (17)
- Potentiation by ethanol consumption of tracheal squamous metaplasia caused by vitamin A deficiency in rats. (1987) (16)
- Dilinoleoylphosphatidylcholine reproduces the antiapoptotic actions of polyenylphosphatidylcholine against ethanol-induced hepatocyte apoptosis. (2003) (16)
- Acceleration of Ethanol Metabolism by High Ethanol Concentrations and Chronic Ethanol Consumption: Role of the Microsomal Ethanol Oxidizing System (MEOS) (1977) (16)
- Alcohol dehydrogenase (ADH) independent ethanol metabolism in deermice lacking ADH (1983) (16)
- Ethanol Metabolism and Pathophysiology of Alcoholic Liver Disease (1985) (16)
- The effect of chronic alcohol administration on cerulein-induced pancreatitis (1995) (16)
- Definition of alcoholism. (1976) (16)
- Venous, arterial, and arterialized-venous blood ammonia levels and their relationship to hepatic encephalopathy after propranolol. (1988) (16)
- Beneficial effects versus toxicity of medium-chain triacylglycerols in rats with NASH. (2008) (16)
- Pathogenesis of alcoholic hypertriglyceridemia and hypercholesterolemia. (1983) (16)
- Combined effects of protein deficiency and chronic ethanol consumption on rat pancreas (1988) (16)
- Association between amino acid alterations and hallucinations in alcoholic patients (1985) (15)
- From alcohol toxicity to treatment. (2005) (15)
- Effect of β‐Carotene on Hepatic Cytochrome P‐450 in Ethanol‐Fed Rats (2001) (15)
- Altered biliary excretion of acetaminophen in rats fed ethanol chronically. (1984) (15)
- Activation of tryptophan pyrrolase after chronic alcohol administration. (1982) (15)
- Alcohol and nutrition; an overview (1989) (15)
- Effects of ethanol and hepatic vitamin A on the proliferation of lipocytes in regenerating rat liver. (1991) (15)
- Depressed oxidative metabolism in skeletal muscle after chronic alcohol consumption. (1982) (15)
- Effects of mineral and vitamin supplementation on the alcohol-induced fatty liver and microsomal induction. (1989) (15)
- A modified colchicine-binding assay for the measurement of total and microtubule-derived tubulin in rat liver. (1983) (15)
- Alcohol, Hormones, and Metabolism (1992) (15)
- Differential effects of retinoids and chronic ethanol consumption on membranes in rats. (1988) (15)
- The photochemical action spectrum of the microsomal ethanol oxidizing system. (1979) (14)
- Carotenoid, retinoid and vitamin E status of the oropharyngeal mucosa in the alcoholic. (1995) (14)
- First-pass metabolism of alcohol (1995) (14)
- Effects of ethanol upon lipid metabolism (1974) (14)
- Alcohol, vitamin A, and b -carotene: adverse interactions, including hepatotoxicity and carcinogenicity 1–3 (1999) (14)
- Alcohol and health: a drink a day won't keep the doctor away. (2003) (14)
- Metabolism of alcohol at high concentrations: role and biochemical nature of the hepatic microsomal ethanol oxidizing system. (1977) (14)
- Effects of ethanol consumption on bioactivation and hepatotoxicity of N-nitrosodimethylamine in rats. (1991) (14)
- Fatty liver, hyperlipemia, and erythrocyte alterations produced by ethanol feeding in the rat. (1969) (14)
- Mechanism of increased gamma glutamyl transpeptidase after chronic alcohol consumption: hepatic microsomal induction rather than dietary imbalance. (1980) (14)
- Ethanol and the liver: a decreasing "threshold" of toxicity. (1979) (13)
- Alcohol and fibrogenesis. (1991) (13)
- Cholecystokinin and Enkephalin levels following ethanol administration in rats (1981) (13)
- Role of peroxisomal fatty acid beta-oxidation in ethanol metabolism. (1989) (13)
- DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione. (2006) (13)
- Aniline hydroxylase microassay suitable for needle biopsy specimens: effects of phosphate and pyrophosphate on aniline hydroxylation. (1972) (13)
- Cytokeratin 7 staining of hepatocytes predicts progression to more severe fibrosis in alcohol-fed baboons. (2003) (13)
- Normal testicular structure and reproductive function in deermice lacking retinol and alcohol dehydrogenase activity. (1984) (13)
- Acute and Chronic Pancreatitis (1974) (13)
- Alcoholic liver injury (1992) (13)
- In vivo role of the microsomal ethanol-oxidizing system in ethanol metabolism by deermice lacking alcohol dehydrogenase. (1988) (12)
- Recommended amounts of nutrients do not abate the toxic effects of an alcohol dose that sustains significant blood levels of ethanol. (1989) (12)
- Stimulation of hepatic fatty acid synthesis by ethanol. (1961) (12)
- Metabolic effects produced by alcohol in the liver and other tissues. (1968) (12)
- Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria (1973) (12)
- Early fine structural changes in the human liver induced by alcohol. (1968) (12)
- Reevaluation of the effects of alcohol consumption on rat liver microtubules: effects of feeding status. (1984) (12)
- PRECURSOR LESIONS OF CIRRHOSIS (1983) (11)
- Re: Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. (1997) (11)
- Acetaldehyde and Acetate (1992) (11)
- Gastritis in the alcoholic: relationship to gastric alcohol metabolism and Helicobacter pylori (1998) (11)
- Role of vitamin A degradation in the control of hepatic levels in the rat. (1989) (11)
- Ethanol feeding can produce secondary alterations in aldehyde dehydrogenase isozymes. (1985) (11)
- Biological Markers of Alcoholism (1992) (11)
- Breath acetaldehyde: evidence of acetaldehyde production by oropharynx microflora and by lung microsomes. (1980) (11)
- Beta carotene, vitamin E, and lung cancer. (1994) (11)
- The unexpected outcomes of medical research: serendipity and the microsomal ethanol oxidizing system. (2004) (11)
- Complications resulting from renal failure in patients with liver disease. (1960) (11)
- Ethanol potentiates squamous metaplasia of the rat trachea caused by vitamin A deficiency. (1984) (11)
- Gastritis and Helicobacter pylori: forty years of antibiotic therapy. (1997) (10)
- Relationship of alcoholic hypertriglyceridemia to stage of liver disease and dietary lipid (2005) (10)
- Role of S-adenosylmethionine in hyperhomocysteinemia and in the treatment of alcoholic liver disease. (2000) (10)
- Alcohol Abuse: Carcinogenic Effects and Fetal Alcohol Syndrome (1992) (10)
- Bile acids in deermice lacking liver alcohol dehydrogenase. (1985) (10)
- Pathogenesis of Alcoholic Liver Disease: An Overview (1977) (10)
- Toxicity of ethanol and other components of alcoholic beverages. (1988) (10)
- Ethanol metabolism in alcohol dehydrogenase deficient deermice is mediated by the microsomal ethanol oxidizing system, not by catalase. (1987) (10)
- Amino Acids and Ethanol (1979) (10)
- Disulfiram treatment increases plasma and red blood cell acetaldehyde in abstinent alcoholics. (1993) (10)
- Liver Disease in Alcoholism (1974) (10)
- Effect of Ethanol on the Activity of Microsomal Enzymes (1971) (9)
- Activation of acetaminophen oxidation in rat liver microsomes by caffeine. (1986) (9)
- Biochemical mechanisms of alcohol-induced hepatic injury. (1991) (9)
- Effects of liver disease on red blood cell acetaldehyde in alcoholics and non-alcoholics. (1991) (9)
- The Combination of S-adenosylmethionine and Dilinoleoylphosphatidylcholine Attenuates Non-alcoholic Steatohepatitis Produced in Rats by a High-Fat Diet. (2007) (9)
- The Research Society on Alcoholism. (2002) (9)
- Model of nonalcoholic steatohepatitis 1 – 4 (2004) (9)
- Aldehyde content of collagen from alcoholic cirrhotic and noncirrhotic human livers. (1979) (9)
- Ethanol and Lipid Disorders, Including Fatty Liver, Hyperlipemia, and Atherosclerosis (1992) (9)
- Effects of butylated hydroxytoluene on the ultrastructure of rat hepatocytes. (1967) (9)
- Dietary Effects on Drug Metabolism (1995) (9)
- Alcoholism: a disease of internal medicine. (1990) (8)
- RECONSTITUTION OF THE HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) IN CONTROL RATS AND AFTER ETHANOL FEEDING (1977) (8)
- Toxicity of beta-carotene and its exacerbation by acetaldehyde in HepG2 cells. (2001) (8)
- Blood markers of alcoholic liver disease. (1988) (8)
- Contribution of gastric oxidation to ethanol first-pass metabolism in baboons. (2000) (8)
- Uridine diphosphoglucose restores lipocyte proliferation in the regenerating liver of ethanol-treated rats. (1992) (8)
- A public health approach for the control of the disease of alcoholism. (1982) (8)
- 2 - Alcohol Metabolism: General Aspects1 (2004) (8)
- Interaction of alcohol and nutritional factors with hepatic fibrosis. (1986) (7)
- Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4. (2001) (7)
- Ultrastructure of the initial stages of hepatic perivenular fibrosis after alcohol. (1981) (7)
- The isolation and properties of mitochondria from rat pancreas. (1984) (7)
- Effects of arachidonic acid on hepatic lipids in ethanol-fed rats. (1990) (7)
- [Effect of oxytetracycline on acidity, ammonia, and urea in gastric juice in normal and uremic subjects]. (1957) (7)
- [Serum lipoproteins and alcoholic diseases of the liver]. (1987) (7)
- Dr. Henry Baker Lecture Interaction of ethanol with drug toxicity. (1980) (7)
- Pathways of Ethanol Metabolism and Related Pathology (1991) (7)
- [Clinical biochemistry of alcohol and its metabolic and hepatic effects]. (1992) (7)
- Absorption of orally administered neomycin and kanamycin, with special reference to patients with severe hepatic and renal diseases. (1959) (7)
- Effect of beta-carotene on hepatic cytochrome P-450 in ethanol-fed rats. (2001) (7)
- Effects of chronic ethanol feeding and acetaldehyde metabolism on calcium transport by rat liver mitochondria. (1983) (7)
- Ethanol metabolism in the liver. (1972) (7)
- Interaction of Ethanol with Other Drugs (1992) (7)
- Role of hepatic microsomal ethanol metabolism. (1971) (7)
- Alcohol and the Digestive Tract (1992) (7)
- Effect of omeprazole on gastric first-pass metabolism of ethanol (1992) (7)
- Idiopathic familial cirrhosis and steatosis in adults (1979) (6)
- The metabolic basis of alcohol's toxicity. (1977) (6)
- Increased hepatic production of alpha amino-n-butyric acid (AANB) after chronic alcohol consumption (1978) (6)
- Prognostic value of perivenular sclerosis in the progression of alcoholic liver injury (1978) (6)
- [Gastroduodenal hemorrhage complicating acute anuria during treatment by artificial kidney]. (1957) (6)
- Alcohol, nutrition, and the liver. (1973) (6)
- Biphasic control of polymorphonuclear cell migration by Kupffer cells. Effect of exposure to metabolic products of ethanol. (1988) (6)
- Gastric metabolism of ethanol in Syrian golden hamster (1995) (6)
- Decreased activity of gastric class III (χ) ADH can explain increased bioavailability of alcohol in women (1998) (6)
- Protein deficiency alters rat pancreatic lipid composition. (1986) (6)
- Clinical Relevance of Alcohol-Drug Interactions (1982) (6)
- Effect of intravenous ethanol on pancreatic secretion in the conscious rat (1981) (6)
- Origin and Pathogenesis of Fatty Acid Accumulation in the Liver During Prolonged Ethanol Consumption (1971) (6)
- Alcohol and cancer (1986) (6)
- Blood Alcohol Levels after Prolonged Use of Histamine-2-Receptor Antagonists (1994) (6)
- Interaction between ethanol metabolism and mixed-function oxidation in alcohol dehydrogenase positive and negative deermice. (1986) (6)
- Effects of Ethanol on Amino Acid and Protein Metabolism (1992) (6)
- Chapter 12. Ethanol and Dyslipoproteinemias (1989) (6)
- Use of the triolein breath test in alcoholics with liver damage. (1987) (6)
- Interaction of Alcohol with Other Drugs and Nutrients (2012) (6)
- Effects of Ethanol on Nutritional Status (1979) (6)
- Attenuation of the ethanol induced hepatic redox change after chronic alcohol consumption: Mechanism and metabolic consequences (1978) (5)
- Nutritional support in chronic diseases of the gastrointestinal tract and the liver (2002) (5)
- Original ContributionsAnalysis of risk factors for chronic hepatic encephalopathy: the role of Helicobacter pylori infection (1998) (5)
- Comparison of the ADH7 gene structure in Caucasian and Japanese subjects. (1995) (5)
- American Medical Society on Alcoholism (AMSA): Recent Growth and Development (1977) (5)
- The role of helicobacter pylori in the pathogenesis and treatment of chronic hepatic encephalopathy (1995) (5)
- The spectrum of alcoholic liver disease. (1990) (5)
- ALCOHOLISM: MEDICAL COMPLICATIONS (1981) (5)
- Plasma glutamate dehydrogenase: A marker of alcoholic liver injury (1980) (5)
- Hepatic pathways of ethanol and acetaldehyde metabolism and their role in the pathogenesis of alcohol-induced liver injury. (1977) (5)
- Lymphocyte subpopulations in patients with alcoholic liver disease. (1986) (5)
- Alcohol research: an endangered species. (2008) (5)
- Ethanol oxidation by deermice mitochondria under physiologic conditions. (1990) (5)
- Metabolic effects of ethanol on the liver and other digestive organs. (1981) (4)
- Blood group antigen expression in the rat colon I. Age‐dependent and region‐related changes (2000) (4)
- Effect of chronic ethanol ingestion on intestinal metabolism and mutagenicity of benzo(alpha)pyrene. (1978) (4)
- Increased activity of intestinal microsomal enzymes after chronic ethanol feeding (1978) (4)
- Effects of chronic alcohol consumption on the metabolism of ethanol. (1987) (4)
- Ethanol and the liver: an example of injury and adaptation. (1971) (4)
- MILESTONES IN LIVER DISEASE The unexpected outcomes of medical research: serendipity and the microsomal ethanol oxidizing system Iseri OA, Lieber CS, Gottlieb LS. The ultrastructure of fatty liver induced by prolonged ethanol ingestion (Am J Pathol 1966;48:535-555) (2004) (4)
- Characteristics of butanol metabolism in alcohol dehydrogenase-deficient deermice. (1989) (4)
- Alcoholic liver disease (1994) (4)
- Possible Role of Microsomal Changes Induced by Ethanol Intake in the Development of Tolerance and Dependence (1973) (4)
- [Interaction of alcohol with the liver, nutrition, drugs and carcinogens]. (1985) (4)
- Effects of acute ethanol administration and chronic ethanol feeding on mixed function oxidation in deermice lacking ADH. (1985) (4)
- The effects of ethanol on the liver. (1972) (4)
- Chapter 11 – Alcohol and the Liver (1965) (4)
- S-Adenosyl-L-methionine: its role in the treatment of liver disorders1–4 (2002) (4)
- Portal fibroblasts and myofibroblasts in baboons after long-term alcohol consumption. (1986) (4)
- Acute and chronic effects of ethanol on biliary secretion of bilirubin and bile acids. (1984) (4)
- Partial characterization of hepatic aldehyde dehydrogenase from the baboon. (1982) (4)
- Alcohol and the terminal hepatic venule. (1982) (4)
- Some Direct Hepatic and Metabolic Effects of Alcohol. (1964) (4)
- NAD(+)-dependent retinol dehydrogenase in liver microsomes. (1990) (3)
- Alcohol, protein nutrition, and liver injury. (1983) (3)
- Lymphocyte subpopulation in patients with alcoholic liver disease (1986) (3)
- Metabolism and Metabolic Actions of Ethanol (1976) (3)
- [Effect of reserpine on gastric secretion in dog]. (1957) (3)
- Nutrition and alcoholism. (2002) (3)
- Hepatic microsomal alcohol oxidizing system adaptive increase in activity following chronic ethanol consumption by a catalase independent mechanism (1975) (3)
- Alcohol, malnutrition and liver disease. (1979) (3)
- Blood acetaldehyde response to ethanol ingestion during the reproductive cycle of the female rat. (1985) (3)
- Lycopene attenuates alcohol-induced apoptosis and oxidative stress in HepG2 cells overexpressing CYP2E1 (2003) (3)
- Dilinoleoylphosphatidylcholine (DLPC) protects against alcohol-induced oxidative stress in rats (2001) (3)
- The effect of chronic ethanol consumption on pathways of ethanol metabolism. (1980) (3)
- Perspectives : do alcohol calories count ? 13 (2005) (3)
- Polyunsaturated phosphatidylcholine (PC) incorporation into phospholipids is greater in pancreas than in liver and protects against alcohol-induced oxidative stress in both (1998) (3)
- PATHOGENESIS OF HEPATIC STEATOSIS. (1963) (3)
- Summary of Discussion (1971) (3)
- Chronic alcoholic hepatic injury in experimental animals and man: biochemical pathways and nutritional factors. (1967) (3)
- The effects of ethanol and diet on hepatic and serum gamma-glutamyltranspeptidase activities in rats. (1985) (3)
- Protection against alcohol-induced hepatocyte apoptosis by polyenylphosphatidylcholine(PPC) is mediated by its main component dilinoleoylphosphatidylcholine(DLPC) (2001) (3)
- Comparison of new methods for measuring carbohydrate-deficient transferrin (CDT): application to a public health approach for the prevention of alcoholic cirrhosis. (1993) (2)
- Metabolic consequences of chronic alcohol consumption: attenuation of hepatic redox changes despite enhanced capacity to eliminate ethanol. (1979) (2)
- Hepatotoxicity of Alcohol (1992) (2)
- Alcoholic fatty liver: its pathogenesis and precursor role for hepatitis and cirrhosis. (1976) (2)
- Dilinoleoylphosphatidylcholine (DLPC) decreases transforming growth factor-B1 (TGF-B1)-mediated collagen production by rat hepatic stellate cells (HSC) (2000) (2)
- Alcoholic liver disease: a public health issue in need of a public health approach. (1993) (2)
- Alcoholism and alcoholic liver injury: new diagnostic and prognostic tests. (1978) (2)
- Alcoholic liver injury, an emerging field. (1981) (2)
- A multidisciplinary approach to alcoholism. (1979) (2)
- Ethanol, protein metabolism and liver injury☆ (1980) (2)
- Metabolic Actions of Ethanol (1979) (2)
- Pathogenesis of Alcoholic Liver Disease (1982) (2)
- Liver disease of the alcoholic: pathogenesis and metabolic complications. (1975) (2)
- Alterations in synaptic membrane molecular order associated with alcoholization and protein deficiency in rats (2004) (2)
- Ethanol metabolism in deermice: role of extrahepatic alcohol dehydrogenase. (1993) (2)
- Interaction of ethanol with drugs and vitamin therapy. (1985) (2)
- EFFECT OF CHRONIC ETHANOL CONSUMPTION ON MICROSOMAL ENZYMES: POTENTIAL RELATIONSHIP TO CHEMICAL MUTAGENESIS AND CARCINOGENESIS (1980) (2)
- Increased vitamin A in esophagus and lungs after moderate ethanol consumption. (1988) (2)
- Hepatic Microsomal E thanol . oxidizing System (1970) (2)
- [Effect of reserpiline on gastric secretion and motility]. (1958) (2)
- The Elderly Alcoholic (1983) (2)
- Effect of ethanol intake on cellular regulation of testosterone-5 alpha-reductase in rat oral tissues. (1981) (2)
- Influence of alcohol on collagen synthesis. (1972) (2)
- Alcoholism and nutrition: a seminar. (1979) (2)
- Metabolism of ethanol and associated interactions with other drugs, carcinogens, and vitamins. (1986) (2)
- Alcohol, vitamin A, and zinc. (1987) (2)
- Alcohol increases hepatic nitric oxide production and its peroxynitrite-mediated toxicity, which are prevented by polyenylphosphatidylcholine (2000) (1)
- Human immunodeficiency virus and hepatitis B virus infections in alcoholics. (1990) (1)
- Effect of alcohol on liver. (1968) (1)
- 212 Leptin stimulates tissue inhibitor of metalloproteinase-(TIMP)-1 in human hepatic stellate cells: respective roles of the JAK-STAT and mitogen-activated protein kinase(MAPK) pathways (2003) (1)
- Methionine, choline and betaine in oral solution for the treatment of alcoholic fatty liver: results of a multicenter randomized double-blind clinical trial (1999) (1)
- H2 antagonists and blood alcohol levels (2005) (1)
- The Research Society on Alcoholism (RSA): 1976-2000. (2000) (1)
- Immunochemical evidence for an ethanol-inducible form of liver microsomal cytochrome P-450 in rodents and primates (1986) (1)
- Plasma glutamate dehydrogenase (GDH) as a marker of alcoholic liver injury (1980) (1)
- Part XI • Chapter 32 – Alcohol and oxidative stress (2000) (1)
- A Report from Your Editor and Editorial Board (1988) (1)
- S-Adenosylmethionine (SAMe): From Molecular Mechanism to Clinical Implication. Symposium (2002) (1)
- Moderator's comments (1979) (1)
- The Effect of Ethanol on Hepatic mRNA Regulation in Baboon and Man (1987) (1)
- Alcohol Metabolism and Its Interaction with Drugs, Liver and Hormones (1982) (1)
- Relationship between ethanol, HDL, and vascular prostacyclin production. (1987) (1)
- A Comparison of Anticholinergic Drugs on Gastric Secretion (1966) (1)
- Alcohol, Amino Acids, and Encephalopathy (1982) (1)
- PATHOGENESIS AND TREATMENT OF ALCOHOLIC LIVER DISEASE (1993) (1)
- Respective Roles of Ethanol and Protein Deficiency in the Pathogenesis of Alcoholic Hepatitis and Cirrhosis (1976) (1)
- Interactions of alcohol and nutrition. (1983) (1)
- Antioxidants and ischaemic heart disease (1997) (1)
- Alcohol-nutrition interaction. (1984) (1)
- Quantification of the Role of Liver Microsomes in Ethanol Metabolism after Chronic Alcohol Consumption and Associated Alterations in Drug and Lipid Metabolism (1973) (1)
- The Metabolism of Alcohol and Its Implications for the Pathogenesis of Disease (2017) (1)
- [Pathogenesis of fatty liver and cirrhosis. I. Biochemical approach]. (1969) (1)
- Combined effects of B-carotene and acetaldehyde on glutathione metabolism in HepG2 cells (2000) (1)
- [Preliminary note concerning the inhibitory effect of atropine and two synthetic parasympathicolytics on posthistaminic gastric secretion in man]. (1956) (1)
- Respective roles of gastric emptying and alcohol metabolism in the gender difference of ethanol’s first-pass metabolism (1998) (1)
- Blood group antigen expression in the rat colon II. Modulation by dietary ethanol consumption (2000) (1)
- [Alcoholic cirrhosis does not necessarily follow alcoholic hepatitis]. (1979) (1)
- Metabolic Adaptation to Alcohol in the Liver and Transition to Tissue Injury, Including Cirrhosis**This work was supported by U.S. Public Health Service grants numbers AA 00224, AM 12511, and VA Project number 5251–01. (1975) (1)
- Alcohol-nutrition interaction (1983). (1984) (1)
- Retinol 4-hydroxylase. (1990) (1)
- Idiopathic familial cirrhosis and steatosis in adults. (1979) (1)
- Cells of the hepatic sinusoid. Volume 2 (1990) (1)
- S-Adenosyl-L-methionine : its role in the treatment of liver disorders 1 – 4 (2002) (1)
- [From alcohol to cirrhosis]. (1986) (1)
- The use of the plasma alpha-amino-n-butyric acid: leucine ratio to identify alcoholics; an unsuccessful test. A comment and a response. (1982) (1)
- [59] NAD+-dependent retinol dehydrogenase in liver microsomes (1990) (1)
- Metabolism of ethanol and its effects upon the liver. (1971) (1)
- Metabolism and metabolic effects of alcohol. (1984) (1)
- [Comparative acute toxicity of atropine, L-hyoscyamine and three synthetic anticholinergic drugs]. (1957) (1)
- Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury. (1991) (1)
- Conversation with Charles S. Lieber. (2001) (0)
- [Comparative statistical study of the pharmacological effects of 2 synthetic anticholinergic drugs (propantheline & oxyphenonium) & atropine]. (1957) (0)
- The Use of the Plasma c-Amino-n-Butyric Acid' Leucine Ratio to Identify Alcoholics; (1982) (0)
- Alcohol-related cirrhosis (2020) (0)
- Treatment research : alcoholics anonymous, the family, serotonin and preference, clinical pharmacology (1989) (0)
- Metabolic tolerance to ethanol. Moderator's comments. (1979) (0)
- American Society of Clinical Nutrition: its state of health in 1976. (1976) (0)
- Answer 2 to Rao Et Al. (1988) (0)
- Fatty liver, cirrhosis, and metabolic effects related to problem drinking. (1968) (0)
- Acknowledgement to reviewers (2017) (0)
- [Comparative inhibitory effect of atropine and of two synthetic parasympathicolytics on posthistaminic gastric secretion in dog]. (1956) (0)
- DiagnosticUtilityof Laboratory Tests inAlcoholicLiverDisease (1994) (0)
- Roles of Alcohol and Helicobacter pylori (2017) (0)
- 885 – ABNORMAL ACETALDEHYDE METABOLISM IN ALCOHOLISM (1977) (0)
- Molecular regulation of an ethanol inducible cytochrome p 450 isozyme p 450 alc in hamsters (1987) (0)
- [Peptic ulcer at site of imperfect gastrectomy; clinical and radiological disappearance after medical therapy]. (1957) (0)
- A novel purification procedure for NADPH cytochrome 450-reductase (1985) (0)
- Hepatic aldehyde dehydrogenase activity in Peromyscus genetically deficient in alcohol dehydrogenase. (1982) (0)
- Histological and biochemical indices of progressive liver injury in patients with alcoholic fatty liver. (1977) (0)
- Characterization of hamster liver microsomal cytochrome P-450 dependent monooxygenases following treatment with xenobiotics (1985) (0)
- [Biochemical and morphological changes of the liver in chronic alcoholism]. (1978) (0)
- The Role of SAMe in the Treatment of Liver Disease (2012) (0)
- Alcohol-relatedDiseasesand Carcinogenesis ' (2006) (0)
- Stereospecificity (ST) of the microsomal ethanol oxidizing system (MEOS) (1987) (0)
- [Comparison of the inhibitory effects of atropine & 2 synthetic parasympatholytics of the postinsulin & basal gastric secretion in man]. (1956) (0)
- [Biochemical and pathophysiological aspects of alcohol metabolism (author's transl)]. (1978) (0)
- A Salute to the AGA Legacy Society (2016) (0)
- ALCOHOLIC LIVER DISEASE AND THE NUTRACEUTICAL REVOLUTION. (2004) (0)
- Alcohol, nutrition, and liver disease. (1980) (0)
- Alcohol Metabolism, Alcohol Intolerence and Alcoholism: Biochemical and Pharmacogenetic Approaches, D.P. Agarwal, H.W. Goedde. Springer Verlag, Berlin (1990), + 184 pages), ISBN: 3-540-51381-7 (1991) (0)
- HEPATIC EFFECTS OF ALCOHOL: INJURY AND ADAPTATION (2009) (0)
- Contents Vol. 12, 1994 (1994) (0)
- [Effects of reserpiline on gastric hypersecretion and hyperacidity after insulin administration]. (1958) (0)
- Alcoholic Liver Injury, Hepatic Manifestations of (2004) (0)
- Ethanol: a twenty year evolution from an "empty" calory engendering malnutrition to a toxic drug. (1977) (0)
- [Comparative study of the inhibiting action of atropine and two synthetic parasympathicolytics on gastric secretion]. (1957) (0)
- [Study of the morphological and metabolic effects of alcohol on liver]. (1971) (0)
- [Effect of 2-methyl-2n-propyl 1,3-propanediol bicarbonate (meprobamate) on gastric secretion following administration of insulin in dogs]. (1957) (0)
- Alcohol-Induced Hepatotoxicity (2020) (0)
- Liver Pathology and Alcohol.Ronald R. Watson (1993) (0)
- WORKSHOP 1: COORDINATION OF RESEARCH AND TEACHING (1971) (0)
- Home About Us Reports Ask the Docs FYI Health Wise (2011) (0)
- [Comparative inhibitory activity of atrophine and two synthetic parasympathicolytics on postinsulin gastric secretion of the dog]. (1956) (0)
- Cytotoxic effects of alcohol on the liver. (1977) (0)
- [Pathways of alcohol catabolism]. (1976) (0)
- Author lndex Vol. 12, 1994 (1994) (0)
- [Ulcerogenic action of oxytetracycline on the stomach of man]. (1957) (0)
- Hepatocellular cytokeratin 7 predicts progression of liver fmrosis in alcohol-fed baboons (2000) (0)
- [Microsomal ethanol oxidizing system in the hepatocyte: its nature and significance for ethanol oxidation (author's transl)]. (1976) (0)
- Alcoholism: A Medical Approach (1980) (0)
- Response ; Fibrogenic Effect of Alcohol in Rat Liver: Role of Diet (1973) (0)
- [Diagnostic value of the determination of various enzymes in the blood]. (1960) (0)
- ANTIOXIDANTS AND ISCHAEMIC HEART DISEASE. AUTHORS' REPLY (1997) (0)
- Alcohol and coronary heart disease. (2003) (0)
- Sequential Production of Fatty Liver, Hel Primates Fed Ethanol with Adequate Diet (alcoholism/fibrosis/microsomes/mitochondria/liquid die (2016) (0)
- [Effect of raumitorine on gastric secretion & motility]. (1958) (0)
- Professional training on alcoholism. Workshop 1: coordination of research and teaching. (1971) (0)
- Alcohol and the liver. Recent developments in preclinical and clinical research. Overview. (1984) (0)
- F3-10 Progress in the treatment of alcoholic liver disease (1995) (0)
- [Effects of penthienate bromide on gastric secretion after insulin administration in dogs]. (1957) (0)
- Henri Temianka Correspondence; (lieber) (1987) (0)
- Because of an expanding epidemic of hepatitis B and C in recent years and a large number of patients with alcoholic liver disease with evolving liver fibrosis and cirrhosis, the diagnosis of the stage of liver fibrosis (2002) (0)
- 598 – NADPH-DEPENDENT HEPATIC MIGROSOMAL ALCOHOL OXIDIZING SYSTEM (MAOSJ IN AGATALASEMIC MICE (1977) (0)
- [Effect of barbiturate derivatives on post-insulin and post-reserpine gastric hypersecretion in dogs]. (1957) (0)
- Acetaldehyde production and transfer by the isolated perfused human placental cotyledon (1986) (0)
- [Effect of khellin on gastric hypersecretion and hyperacidity after histamine administration to dogs]. (1956) (0)
- MECHANISM OF LIVER CELL DAMAGE (1981) (0)
- Hepatitis C: An Australian Perspective (2002) (0)
- Effects of Prolonged Ethanol Intake in Dietary, Adipose, and Endogenously Fatty Acids in the Pathogenesis Alcoholic Fatty Liver * Man: Role of Synthesized of the (2004) (0)
- [Effects on reserpine-free extracts of Rauwolfia vomitoria on gastric secretion in dogs]. (1957) (0)
- Interactions of ethanol, drug and lipid metabolism; adaptive changes after ethanol consumption. (1970) (0)
- Subject lndex Vol. 12, 1994 (1994) (0)
- [Pathogenesis of alcoholic liver injury (author's transl)]. (1979) (0)
- Comparative study of the inhibitory effects of parasympathicolytic substances on gastric secretion in rats. (1956) (0)
- The Effects of Chronic Ethanol Consumption and Acetaldehyde on Hepatic Mitochondria (1976) (0)
- [What relation exists between ethanol, atherosclerosis and high density lipoproteins]. (1987) (0)
- Baboon Model for Alcoholic Liver Disease: 1973–2003 (2009) (0)
- Future Directions in Biomedical Research on Alcoholism (1991) (0)
- Treatment of alcoholic liver injury. (1985) (0)
- Cells of the hepatic sinusoid. Volume 2: Edited by E. Wisse, D. L. Knook, and K. Decker. 508 pp., $100.00. The Kupffer Cell Foundation, Rijswijk, The Netherlands, 1989. ISBN: 90-800079-3-5 (1990) (0)
- For NASH prevention caloric restriction is more important than dietary composition (2003) (0)
- $96.50 (x + 184 pages) D.P. Agarwal H.W. Goedde (1991) (0)
- Chronic alcohol ingestion and nutrition (1991) (0)
- Reply to the Letter of Drs. Rao, Sankaran and Larkin (1988) (0)
- Acetaminophen Metabolism during Alcoholic Liver Injury (1984) (0)
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What Schools Are Affiliated With Charles S. Lieber?
Charles S. Lieber is affiliated with the following schools:
